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Volumn 108, Issue 35, 2011, Pages 14497-14502

OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR NANOG;

EID: 80052284848     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1111309108     Document Type: Article
Times cited : (105)

References (47)
  • 1
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik W. (2007) Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447:425-432.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 2
    • 64249157351 scopus 로고    scopus 로고
    • Epigenetic reprogramming and induced pluripotency
    • Hochedlinger K., Plath K. (2009) Epigenetic reprogramming and induced pluripotency. Development 136:509-523.
    • (2009) Development , vol.136 , pp. 509-523
    • Hochedlinger, K.1    Plath, K.2
  • 4
    • 78149316177 scopus 로고    scopus 로고
    • Epigenetic control of embryonic stem cell fate
    • Christophersen N.S., Helin K. (2010) Epigenetic control of embryonic stem cell fate. J Exp Med 207:2287-2295.
    • (2010) J Exp Med , vol.207 , pp. 2287-2295
    • Christophersen, N.S.1    Helin, K.2
  • 5
    • 33646070846 scopus 로고    scopus 로고
    • A bivalent chromatin structure marks key developmental genes in embryonic stem cells
    • Bernstein B.E., et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125:315-326.
    • (2006) Cell , vol.125 , pp. 315-326
    • Bernstein, B.E.1
  • 6
    • 33646872978 scopus 로고    scopus 로고
    • Chromatin signatures of pluripotent cell lines
    • Azuara V., et al. (2006) Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8: 532-538.
    • (2006) Nat Cell Biol , vol.8 , pp. 532-538
    • Azuara, V.1
  • 7
    • 39149130361 scopus 로고    scopus 로고
    • Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
    • DOI 10.1016/j.cell.2008.01.015, PII S0092867408001153
    • Jaenisch R., Young R. (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132:567-582. (Pubitemid 351253686)
    • (2008) Cell , vol.132 , Issue.4 , pp. 567-582
    • Jaenisch, R.1    Young, R.2
  • 8
    • 0023663417 scopus 로고
    • Nucleosomes inhibit the initiation of transcription but allowchain elongation with the displacement of histones
    • Lorch Y., LaPointe J.W., Kornberg R.D. (1987) Nucleosomes inhibit the initiation of transcription but allowchain elongation with the displacement of histones. Cell 49:203-210.
    • (1987) Cell , vol.49 , pp. 203-210
    • Lorch, Y.1    LaPointe, J.W.2    Kornberg, R.D.3
  • 9
    • 22544432870 scopus 로고    scopus 로고
    • The dynamics of chromatinremodeling at promoters
    • Mellor J. (2005) The dynamics of chromatinremodeling at promoters.Mol Cell 19:147-157.
    • (2005) Mol Cell , vol.19 , pp. 147-157
    • Mellor, J.1
  • 10
  • 12
    • 60349089645 scopus 로고    scopus 로고
    • Nucleosome positioning and gene regulation:Advances through genomics
    • Jiang C., Pugh B.F. (2009) Nucleosome positioning and gene regulation:Advances through genomics. Nat Rev Genet 10:161-172.
    • (2009) Nat Rev Genet , vol.10 , pp. 161-172
    • Jiang, C.1    Pugh, B.F.2
  • 13
    • 68149150830 scopus 로고    scopus 로고
    • H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions
    • Jin C., et al. (2009) H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions. Nat Genet 41: 941-945.
    • (2009) Nat Genet , vol.41 , pp. 941-945
    • Jin, C.1
  • 14
    • 77950262538 scopus 로고    scopus 로고
    • Nucleosome dynamics define transcriptional enhancers
    • He H.H., et al. (2010) Nucleosome dynamics define transcriptional enhancers. Nat Genet 42:343-347.
    • (2010) Nat Genet , vol.42 , pp. 343-347
    • He, H.H.1
  • 15
    • 68349125112 scopus 로고    scopus 로고
    • What controls nucleosome positions?
    • Segal E., Widom J. (2009) What controls nucleosome positions? Trends Genet 25:335-343.
    • (2009) Trends Genet , vol.25 , pp. 335-343
    • Segal, E.1    Widom, J.2
  • 16
    • 77957883572 scopus 로고    scopus 로고
    • Gene regulation by nucleosome positioning
    • Bai L., Morozov A.V. (2010) Gene regulation by nucleosome positioning. Trends Genet 26:476-483.
    • (2010) Trends Genet , vol.26 , pp. 476-483
    • Bai, L.1    Morozov, A.V.2
  • 17
    • 77952414230 scopus 로고    scopus 로고
    • Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer
    • Wolff E.M., et al. (2010) Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. PLoS Genet 6:e1000917.
    • (2010) PLoS Genet , vol.6
    • Wolff, E.M.1
  • 18
    • 77956931047 scopus 로고    scopus 로고
    • H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes
    • Kelly T.K., et al. (2010) H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol Cell 39:901-911.
    • (2010) Mol Cell , vol.39 , pp. 901-911
    • Kelly, T.K.1
  • 19
    • 0027453115 scopus 로고
    • Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT
    • Damjanov I., Horvat B., Gibas Z. (1993) Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT. Lab Invest 68:220-232. (Pubitemid 23084295)
    • (1993) Laboratory Investigation , vol.68 , Issue.2 , pp. 220-232
    • Damjanov, I.1    Horvat, B.2    Gibas, Z.3
  • 20
    • 67651003097 scopus 로고    scopus 로고
    • Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells:Involvement of Nanog suppression
    • You J.S., et al. (2009) Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells:Involvement of Nanog suppression. Cancer Res 69:5716-5725.
    • (2009) Cancer Res , vol.69 , pp. 5716-5725
    • You, J.S.1
  • 23
    • 34248141152 scopus 로고    scopus 로고
    • Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract
    • DOI 10.1091/mbc.E07-01-0029
    • Freberg C.T., Dahl J.A., Timoskainen S., Collas P. (2007) Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract. Mol Biol Cell 18:1543-1553. (Pubitemid 46717539)
    • (2007) Molecular Biology of the Cell , vol.18 , Issue.5 , pp. 1543-1553
    • Freberg, C.T.1    Dahl, J.A.2    Timoskainen, S.3    Collas, P.4
  • 24
    • 70349865017 scopus 로고    scopus 로고
    • KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells
    • Chan K.K., et al. (2009) KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells. Stem Cells 27:2114-2125.
    • (2009) Stem Cells , vol.27 , pp. 2114-2125
    • Chan, K.K.1
  • 25
    • 21744444920 scopus 로고    scopus 로고
    • Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells
    • Chew J.L., et al. (2005) Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 25:6031-6046.
    • (2005) Mol Cell Biol , vol.25 , pp. 6031-6046
    • Chew, J.L.1
  • 27
    • 77949900026 scopus 로고    scopus 로고
    • An Oct4-centered protein interaction network in embryonic stem cells
    • Van den Berg D.L., et al. (2010) An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 6:369-381.
    • (2010) Cell Stem Cell , vol.6 , pp. 369-381
    • Van Den Berg, D.L.1
  • 28
    • 77949881949 scopus 로고    scopus 로고
    • An expanded Oct4 interaction network:Implications for stem cell biology, development, and disease
    • Pardo M., et al. (2010) An expanded Oct4 interaction network:Implications for stem cell biology, development, and disease. Cell Stem Cell 6:382-395.
    • (2010) Cell Stem Cell , vol.6 , pp. 382-395
    • Pardo, M.1
  • 29
    • 75749101495 scopus 로고    scopus 로고
    • Chromatin remodelling during development
    • Ho L., Crabtree G.R. (2010) Chromatin remodelling during development. Nature 463: 474-484.
    • (2010) Nature , vol.463 , pp. 474-484
    • Ho, L.1    Crabtree, G.R.2
  • 30
    • 77249178763 scopus 로고    scopus 로고
    • DNA methylation increases nucleosome compaction and rigidity
    • Choy J.S., et al. (2010) DNA methylation increases nucleosome compaction and rigidity. J Am Chem Soc 132:1782-1783.
    • (2010) J Am Chem Soc , vol.132 , pp. 1782-1783
    • Choy, J.S.1
  • 31
    • 77953566957 scopus 로고    scopus 로고
    • Concise review:Isoforms of OCT4 contribute to the confusing diversity in stem cell biology
    • Wang X., Dai J. (2010) Concise review:Isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells 28:885-893.
    • (2010) Stem Cells , vol.28 , pp. 885-893
    • Wang, X.1    Dai, J.2
  • 32
    • 77953305748 scopus 로고    scopus 로고
    • A structural perspective on the where, how, why, and what of nucleosome positioning
    • Arya G., Maitra A., Grigoryev S.A. (2010) A structural perspective on the where, how, why, and what of nucleosome positioning. J Biomol Struct Dyn 27:803-820.
    • (2010) J Biomol Struct Dyn , vol.27 , pp. 803-820
    • Arya, G.1    Maitra, A.2    Grigoryev, S.A.3
  • 33
    • 70249121045 scopus 로고    scopus 로고
    • The logic of chromatin architecture and remodelling at promoters
    • Cairns B.R. (2009) The logic of chromatin architecture and remodelling at promoters. Nature 461:193-198.
    • (2009) Nature , vol.461 , pp. 193-198
    • Cairns, B.R.1
  • 34
    • 56149093048 scopus 로고    scopus 로고
    • Transcriptional and epigenetic regulations of embryonic stem cells
    • Ng J.H., Heng J.C., Loh Y.H., Ng H.H. (2008) Transcriptional and epigenetic regulations of embryonic stem cells. Mutat Res 647:52-58.
    • (2008) Mutat Res , vol.647 , pp. 52-58
    • Ng, J.H.1    Heng, J.C.2    Loh, Y.H.3    Ng, H.H.4
  • 35
    • 78149465975 scopus 로고    scopus 로고
    • A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
    • Chia N.Y., et al. (2010) A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468:316-320.
    • (2010) Nature , vol.468 , pp. 316-320
    • Chia, N.Y.1
  • 36
    • 79956316470 scopus 로고    scopus 로고
    • A packing mechanism for nucleosome organization reconstituted across a eukaryotic genome
    • Zhang Z., et al. (2011) A packing mechanism for nucleosome organization reconstituted across a eukaryotic genome. Science 332:977-980.
    • (2011) Science , vol.332 , pp. 977-980
    • Zhang, Z.1
  • 37
    • 0023657424 scopus 로고
    • Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
    • Lock L.F., Takagi N., Martin G.R. (1987) Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation. Cell 48:39-46.
    • (1987) Cell , vol.48 , pp. 39-46
    • Lock, L.F.1    Takagi, N.2    Martin, G.R.3
  • 38
    • 33645132331 scopus 로고    scopus 로고
    • G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
    • Feldman N., et al. (2006) G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol 8:188-194.
    • (2006) Nat Cell Biol , vol.8 , pp. 188-194
    • Feldman, N.1
  • 40
    • 0842307061 scopus 로고    scopus 로고
    • Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9
    • DOI 10.1038/sj.emboj.7600013
    • Mutskov V., Felsenfeld G. (2004) Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J 23:138-149. (Pubitemid 38165754)
    • (2004) EMBO Journal , vol.23 , Issue.1 , pp. 138-149
    • Mutskov, V.1    Felsenfeld, G.2
  • 41
    • 55549145072 scopus 로고    scopus 로고
    • De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
    • Epsztejn-Litman S., et al. (2008) De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nat Struct Mol Biol 15:1176-1183.
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 1176-1183
    • Epsztejn-Litman, S.1
  • 43
    • 70349322609 scopus 로고    scopus 로고
    • Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
    • Jeong S., et al. (2009) Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol 29:5366-5376.
    • (2009) Mol Cell Biol , vol.29 , pp. 5366-5376
    • Jeong, S.1
  • 44
    • 79952258043 scopus 로고    scopus 로고
    • Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance
    • Sharma S., De Carvalho D.D., Jeong S., Jones P.A., Liang G. (2011) Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet 7:e1001286.
    • (2011) PLoS Genet , vol.7
    • Sharma, S.1    De Carvalho, D.D.2    Jeong, S.3    Jones, P.A.4    Liang, G.5
  • 45
    • 70350046301 scopus 로고    scopus 로고
    • Rethinking how DNA methylation patterns are maintained
    • Jones P.A., Liang G. (2009) Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 10:805-811.
    • (2009) Nat Rev Genet , vol.10 , pp. 805-811
    • Jones, P.A.1    Liang, G.2
  • 47
    • 49649125042 scopus 로고    scopus 로고
    • Genome-scale DNA methylation maps of pluripotent and differentiated cells
    • Meissner A., et al. (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454:766-770.
    • (2008) Nature , vol.454 , pp. 766-770
    • Meissner, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.