-
1
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik W. (2007) Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447:425-432.
-
(2007)
Nature
, vol.447
, pp. 425-432
-
-
Reik, W.1
-
2
-
-
64249157351
-
Epigenetic reprogramming and induced pluripotency
-
Hochedlinger K., Plath K. (2009) Epigenetic reprogramming and induced pluripotency. Development 136:509-523.
-
(2009)
Development
, vol.136
, pp. 509-523
-
-
Hochedlinger, K.1
Plath, K.2
-
4
-
-
78149316177
-
Epigenetic control of embryonic stem cell fate
-
Christophersen N.S., Helin K. (2010) Epigenetic control of embryonic stem cell fate. J Exp Med 207:2287-2295.
-
(2010)
J Exp Med
, vol.207
, pp. 2287-2295
-
-
Christophersen, N.S.1
Helin, K.2
-
5
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein B.E., et al. (2006) A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125:315-326.
-
(2006)
Cell
, vol.125
, pp. 315-326
-
-
Bernstein, B.E.1
-
6
-
-
33646872978
-
Chromatin signatures of pluripotent cell lines
-
Azuara V., et al. (2006) Chromatin signatures of pluripotent cell lines. Nat Cell Biol 8: 532-538.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 532-538
-
-
Azuara, V.1
-
7
-
-
39149130361
-
Stem Cells, the Molecular Circuitry of Pluripotency and Nuclear Reprogramming
-
DOI 10.1016/j.cell.2008.01.015, PII S0092867408001153
-
Jaenisch R., Young R. (2008) Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132:567-582. (Pubitemid 351253686)
-
(2008)
Cell
, vol.132
, Issue.4
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
8
-
-
0023663417
-
Nucleosomes inhibit the initiation of transcription but allowchain elongation with the displacement of histones
-
Lorch Y., LaPointe J.W., Kornberg R.D. (1987) Nucleosomes inhibit the initiation of transcription but allowchain elongation with the displacement of histones. Cell 49:203-210.
-
(1987)
Cell
, vol.49
, pp. 203-210
-
-
Lorch, Y.1
LaPointe, J.W.2
Kornberg, R.D.3
-
9
-
-
22544432870
-
The dynamics of chromatinremodeling at promoters
-
Mellor J. (2005) The dynamics of chromatinremodeling at promoters.Mol Cell 19:147-157.
-
(2005)
Mol Cell
, vol.19
, pp. 147-157
-
-
Mellor, J.1
-
10
-
-
39749145198
-
Dynamic Regulation of Nucleosome Positioning in the Human Genome
-
DOI 10.1016/j.cell.2008.02.022, PII S0092867408002705
-
Schones D.E., et al. (2008) Dynamic regulation of nucleosome positioning in the human genome. Cell 132:887-898. (Pubitemid 351312809)
-
(2008)
Cell
, vol.132
, Issue.5
, pp. 887-898
-
-
Schones, D.E.1
Cui, K.2
Cuddapah, S.3
Roh, T.-Y.4
Barski, A.5
Wang, Z.6
Wei, G.7
Zhao, K.8
-
11
-
-
33847334699
-
Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome
-
DOI 10.1038/ng1966, PII NG1966
-
Heintzman N.D., et al. (2007) Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome. Nat Genet 39:311-318. (Pubitemid 46328487)
-
(2007)
Nature Genetics
, vol.39
, Issue.3
, pp. 311-318
-
-
Heintzman, N.D.1
Stuart, R.K.2
Hon, G.3
Fu, Y.4
Ching, C.W.5
Hawkins, R.D.6
Barrera, L.O.7
Van Calcar, S.8
Qu, C.9
Ching, K.A.10
Wang, W.11
Weng, Z.12
Green, R.D.13
Crawford, G.E.14
Ren, B.15
-
12
-
-
60349089645
-
Nucleosome positioning and gene regulation:Advances through genomics
-
Jiang C., Pugh B.F. (2009) Nucleosome positioning and gene regulation:Advances through genomics. Nat Rev Genet 10:161-172.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 161-172
-
-
Jiang, C.1
Pugh, B.F.2
-
13
-
-
68149150830
-
H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions
-
Jin C., et al. (2009) H3.3/H2A.Z double variant-containing nucleosomes mark 'nucleosome-free regions' of active promoters and other regulatory regions. Nat Genet 41: 941-945.
-
(2009)
Nat Genet
, vol.41
, pp. 941-945
-
-
Jin, C.1
-
14
-
-
77950262538
-
Nucleosome dynamics define transcriptional enhancers
-
He H.H., et al. (2010) Nucleosome dynamics define transcriptional enhancers. Nat Genet 42:343-347.
-
(2010)
Nat Genet
, vol.42
, pp. 343-347
-
-
He, H.H.1
-
15
-
-
68349125112
-
What controls nucleosome positions?
-
Segal E., Widom J. (2009) What controls nucleosome positions? Trends Genet 25:335-343.
-
(2009)
Trends Genet
, vol.25
, pp. 335-343
-
-
Segal, E.1
Widom, J.2
-
16
-
-
77957883572
-
Gene regulation by nucleosome positioning
-
Bai L., Morozov A.V. (2010) Gene regulation by nucleosome positioning. Trends Genet 26:476-483.
-
(2010)
Trends Genet
, vol.26
, pp. 476-483
-
-
Bai, L.1
Morozov, A.V.2
-
17
-
-
77952414230
-
Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer
-
Wolff E.M., et al. (2010) Hypomethylation of a LINE-1 promoter activates an alternate transcript of the MET oncogene in bladders with cancer. PLoS Genet 6:e1000917.
-
(2010)
PLoS Genet
, vol.6
-
-
Wolff, E.M.1
-
18
-
-
77956931047
-
H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes
-
Kelly T.K., et al. (2010) H2A.Z maintenance during mitosis reveals nucleosome shifting on mitotically silenced genes. Mol Cell 39:901-911.
-
(2010)
Mol Cell
, vol.39
, pp. 901-911
-
-
Kelly, T.K.1
-
19
-
-
0027453115
-
Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT
-
Damjanov I., Horvat B., Gibas Z. (1993) Retinoic acid-induced differentiation of the developmentally pluripotent human germ cell tumor-derived cell line, NCCIT. Lab Invest 68:220-232. (Pubitemid 23084295)
-
(1993)
Laboratory Investigation
, vol.68
, Issue.2
, pp. 220-232
-
-
Damjanov, I.1
Horvat, B.2
Gibas, Z.3
-
20
-
-
67651003097
-
Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells:Involvement of Nanog suppression
-
You J.S., et al. (2009) Depletion of embryonic stem cell signature by histone deacetylase inhibitor in NCCIT cells:Involvement of Nanog suppression. Cancer Res 69:5716-5725.
-
(2009)
Cancer Res
, vol.69
, pp. 5716-5725
-
-
You, J.S.1
-
21
-
-
33748998743
-
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival
-
DOI 10.1073/pnas.0604602103
-
Egger G., et al. (2006) Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci USA 103:14080-14085. (Pubitemid 44452983)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.38
, pp. 14080-14085
-
-
Egger, G.1
Jeong, S.2
Escobar, S.G.3
Cortez, C.C.4
Li, T.W.H.5
Saito, Y.6
Yoo, C.B.7
Jones, P.A.8
Liang, G.9
-
22
-
-
18344390653
-
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
-
DOI 10.1038/416552a
-
Rhee I., et al. (2002) DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. Nature 416:552-556. (Pubitemid 34288859)
-
(2002)
Nature
, vol.416
, Issue.6880
, pp. 552-556
-
-
Rhee, I.1
Bachman, K.E.2
Park, B.H.3
Jair, K.-W.4
Yen, R.-W.C.5
Schuebel, K.E.6
Cui, H.7
Feinberg, A.P.8
Lengauer, C.9
Kinzler, K.W.10
Baylin, S.B.11
Vogelstein, B.12
-
23
-
-
34248141152
-
Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract
-
DOI 10.1091/mbc.E07-01-0029
-
Freberg C.T., Dahl J.A., Timoskainen S., Collas P. (2007) Epigenetic reprogramming of OCT4 and NANOG regulatory regions by embryonal carcinoma cell extract. Mol Biol Cell 18:1543-1553. (Pubitemid 46717539)
-
(2007)
Molecular Biology of the Cell
, vol.18
, Issue.5
, pp. 1543-1553
-
-
Freberg, C.T.1
Dahl, J.A.2
Timoskainen, S.3
Collas, P.4
-
24
-
-
70349865017
-
KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells
-
Chan K.K., et al. (2009) KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells. Stem Cells 27:2114-2125.
-
(2009)
Stem Cells
, vol.27
, pp. 2114-2125
-
-
Chan, K.K.1
-
25
-
-
21744444920
-
Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells
-
Chew J.L., et al. (2005) Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol 25:6031-6046.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 6031-6046
-
-
Chew, J.L.1
-
26
-
-
14844359620
-
Octamer and sox elements are required for transcriptional cis regulation of Nanog gene expression
-
DOI 10.1128/MCB.25.6.2475-2485.2005
-
Kuroda T., et al. (2005) Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol Cell Biol 25:2475-2485. (Pubitemid 40354640)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.6
, pp. 2475-2485
-
-
Kuroda, T.1
Tada, M.2
Kubota, H.3
Kimura, H.4
Hatano, S.-Y.5
Suemori, H.6
Nakatsuji, N.7
Tada, T.8
-
27
-
-
77949900026
-
An Oct4-centered protein interaction network in embryonic stem cells
-
Van den Berg D.L., et al. (2010) An Oct4-centered protein interaction network in embryonic stem cells. Cell Stem Cell 6:369-381.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 369-381
-
-
Van Den Berg, D.L.1
-
28
-
-
77949881949
-
An expanded Oct4 interaction network:Implications for stem cell biology, development, and disease
-
Pardo M., et al. (2010) An expanded Oct4 interaction network:Implications for stem cell biology, development, and disease. Cell Stem Cell 6:382-395.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 382-395
-
-
Pardo, M.1
-
29
-
-
75749101495
-
Chromatin remodelling during development
-
Ho L., Crabtree G.R. (2010) Chromatin remodelling during development. Nature 463: 474-484.
-
(2010)
Nature
, vol.463
, pp. 474-484
-
-
Ho, L.1
Crabtree, G.R.2
-
30
-
-
77249178763
-
DNA methylation increases nucleosome compaction and rigidity
-
Choy J.S., et al. (2010) DNA methylation increases nucleosome compaction and rigidity. J Am Chem Soc 132:1782-1783.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 1782-1783
-
-
Choy, J.S.1
-
31
-
-
77953566957
-
Concise review:Isoforms of OCT4 contribute to the confusing diversity in stem cell biology
-
Wang X., Dai J. (2010) Concise review:Isoforms of OCT4 contribute to the confusing diversity in stem cell biology. Stem Cells 28:885-893.
-
(2010)
Stem Cells
, vol.28
, pp. 885-893
-
-
Wang, X.1
Dai, J.2
-
32
-
-
77953305748
-
A structural perspective on the where, how, why, and what of nucleosome positioning
-
Arya G., Maitra A., Grigoryev S.A. (2010) A structural perspective on the where, how, why, and what of nucleosome positioning. J Biomol Struct Dyn 27:803-820.
-
(2010)
J Biomol Struct Dyn
, vol.27
, pp. 803-820
-
-
Arya, G.1
Maitra, A.2
Grigoryev, S.A.3
-
33
-
-
70249121045
-
The logic of chromatin architecture and remodelling at promoters
-
Cairns B.R. (2009) The logic of chromatin architecture and remodelling at promoters. Nature 461:193-198.
-
(2009)
Nature
, vol.461
, pp. 193-198
-
-
Cairns, B.R.1
-
34
-
-
56149093048
-
Transcriptional and epigenetic regulations of embryonic stem cells
-
Ng J.H., Heng J.C., Loh Y.H., Ng H.H. (2008) Transcriptional and epigenetic regulations of embryonic stem cells. Mutat Res 647:52-58.
-
(2008)
Mutat Res
, vol.647
, pp. 52-58
-
-
Ng, J.H.1
Heng, J.C.2
Loh, Y.H.3
Ng, H.H.4
-
35
-
-
78149465975
-
A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity
-
Chia N.Y., et al. (2010) A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature 468:316-320.
-
(2010)
Nature
, vol.468
, pp. 316-320
-
-
Chia, N.Y.1
-
36
-
-
79956316470
-
A packing mechanism for nucleosome organization reconstituted across a eukaryotic genome
-
Zhang Z., et al. (2011) A packing mechanism for nucleosome organization reconstituted across a eukaryotic genome. Science 332:977-980.
-
(2011)
Science
, vol.332
, pp. 977-980
-
-
Zhang, Z.1
-
37
-
-
0023657424
-
Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
-
Lock L.F., Takagi N., Martin G.R. (1987) Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation. Cell 48:39-46.
-
(1987)
Cell
, vol.48
, pp. 39-46
-
-
Lock, L.F.1
Takagi, N.2
Martin, G.R.3
-
38
-
-
33645132331
-
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
-
Feldman N., et al. (2006) G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat Cell Biol 8:188-194.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 188-194
-
-
Feldman, N.1
-
39
-
-
18144415066
-
Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter
-
DOI 10.1128/MCB.25.10.3923-3933.2005
-
Strunnikova M., et al. (2005) Chromatin inactivation precedes de novo DNA methylation during the progressive epigenetic silencing of the RASSF1A promoter. Mol Cell Biol 25:3923-3933. (Pubitemid 40617644)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.10
, pp. 3923-3933
-
-
Strunnikova, M.1
Schagdarsurengin, U.2
Kehlen, A.3
Garbe, J.C.4
Stampfer, M.R.5
Dammann, R.6
-
40
-
-
0842307061
-
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9
-
DOI 10.1038/sj.emboj.7600013
-
Mutskov V., Felsenfeld G. (2004) Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9. EMBO J 23:138-149. (Pubitemid 38165754)
-
(2004)
EMBO Journal
, vol.23
, Issue.1
, pp. 138-149
-
-
Mutskov, V.1
Felsenfeld, G.2
-
41
-
-
55549145072
-
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
-
Epsztejn-Litman S., et al. (2008) De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes. Nat Struct Mol Biol 15:1176-1183.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 1176-1183
-
-
Epsztejn-Litman, S.1
-
42
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
DOI 10.1038/nature05987, PII NATURE05987
-
Ooi S.K.T., et al. (2007) DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448:714-717. (Pubitemid 47236857)
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 714-717
-
-
Ooi, S.K.T.1
Qiu, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
Erdjument-Bromage, H.7
Tempst, P.8
Lin, S.-P.9
Allis, C.D.10
Cheng, X.11
Bestor, T.H.12
-
43
-
-
70349322609
-
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
-
Jeong S., et al. (2009) Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol 29:5366-5376.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5366-5376
-
-
Jeong, S.1
-
44
-
-
79952258043
-
Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance
-
Sharma S., De Carvalho D.D., Jeong S., Jones P.A., Liang G. (2011) Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance. PLoS Genet 7:e1001286.
-
(2011)
PLoS Genet
, vol.7
-
-
Sharma, S.1
De Carvalho, D.D.2
Jeong, S.3
Jones, P.A.4
Liang, G.5
-
45
-
-
70350046301
-
Rethinking how DNA methylation patterns are maintained
-
Jones P.A., Liang G. (2009) Rethinking how DNA methylation patterns are maintained. Nat Rev Genet 10:805-811.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 805-811
-
-
Jones, P.A.1
Liang, G.2
-
47
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A., et al. (2008) Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454:766-770.
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
|