-
1
-
-
0034681176
-
A method for detecting abasic sites in living cells: Agedependent changes in base excision repair
-
Atamna H, Cheung I, Ames BN. A method for detecting abasic sites in living cells: agedependent changes in base excision repair. Proc Natl Acad Sci USA. 2000;97(2):686-91.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, Issue.2
, pp. 686-691
-
-
Atamna, H.1
Cheung, I.2
Ames, B.N.3
-
2
-
-
77950338981
-
DNA repair in premature aging disorders and neurodegeneration
-
Coppede F, Migliore L. DNA repair in premature aging disorders and neurodegeneration. Curr Aging Sci. 2010;3(1):3-19.
-
(2010)
Curr Aging Sci.
, vol.3
, Issue.1
, pp. 3-19
-
-
Coppede, F.1
Migliore, L.2
-
3
-
-
84862015595
-
Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains
-
Wang S, Okun MS, Suslov O, Zheng T, Mc-Farland NR, Vedam-Mai V, et al. Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains. Brain Res. 2012;1464:61-72.
-
(2012)
Brain Res.
, vol.1464
, pp. 61-72
-
-
Wang, S.1
Okun, M.S.2
Suslov, O.3
Zheng, T.4
Mc-Farland, N.R.5
Vedam-Mai, V.6
-
4
-
-
44949085340
-
The role of the DNA damage response in neuronal development, organization and maintenance
-
Barzilai A, Biton S, Shiloh Y. The role of the DNA damage response in neuronal development, organization and maintenance. DNA Repair (Amst). 2008;7(7):1010-27.
-
(2008)
DNA Repair (Amst).
, vol.7
, Issue.7
, pp. 1010-1027
-
-
Barzilai, A.1
Biton, S.2
Shiloh, Y.3
-
5
-
-
34250195047
-
DNA damage-induced signalling in ataxia-telangiectasia and related syndromes
-
Lavin MF, Kozlov S. DNA damage-induced signalling in ataxia-telangiectasia and related syndromes. Radiother Oncol. 2007;83(3):231-7.
-
(2007)
Radiother Oncol.
, vol.83
, Issue.3
, pp. 231-237
-
-
Lavin, M.F.1
Kozlov, S.2
-
6
-
-
0942268166
-
DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy
-
Lehmann AR. DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy. Biochimie. 2003;85(11):1101-11.
-
(2003)
Biochimie.
, vol.85
, Issue.11
, pp. 1101-1111
-
-
Lehmann, A.R.1
-
7
-
-
0032076190
-
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
-
Varon R, Vissinga C, Platzer M, Cerosaletti KM, Chrzanowska KH, Saar K, et al. Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell. 1998;93(3):467-76.
-
(1998)
Cell.
, vol.93
, Issue.3
, pp. 467-476
-
-
Varon, R.1
Vissinga, C.2
Platzer, M.3
Cerosaletti, K.M.4
Chrzanowska, K.H.5
Saar, K.6
-
8
-
-
0022308073
-
Sequence of cellular events in cerebellar ontogeny relevant to expression of neuronal abnormalities in ataxia-telangiectasia
-
Vinters HV, Gatti RA, Rakic P. Sequence of cellular events in cerebellar ontogeny relevant to expression of neuronal abnormalities in ataxia-telangiectasia. Kroc Found Ser. 1985;19:233-55.
-
(1985)
Kroc Found Ser.
, vol.19
, pp. 233-255
-
-
Vinters, H.V.1
Gatti, R.A.2
Rakic, P.3
-
9
-
-
0032427628
-
The role of ATM in DNA damage responses and cancer
-
Canman CE, Lim DS. The role of ATM in DNA damage responses and cancer. Oncogene. 1998;17(25):3301-8.
-
(1998)
Oncogene.
, vol.17
, Issue.25
, pp. 3301-3308
-
-
Canman, C.E.1
Lim, D.S.2
-
10
-
-
67649859655
-
Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain
-
Iourov IY, Vorsanova SG, Liehr T, Kolotii AD, Yurov YB. Increased chromosome instability dramatically disrupts neural genome integrity and mediates cerebellar degeneration in the ataxia-telangiectasia brain. Hum Mol Genet. 2009;18(14):2656-69.
-
(2009)
Hum Mol Genet.
, vol.18
, Issue.14
, pp. 2656-2669
-
-
Iourov, I.Y.1
Vorsanova, S.G.2
Liehr, T.3
Kolotii, A.D.4
Yurov, Y.B.5
-
11
-
-
0033212125
-
ATM: The protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia
-
Lavin MF, Khanna KK. ATM: the protein encoded by the gene mutated in the radiosensitive syndrome ataxia-telangiectasia. Int J Radiat Biol. 1999;75(10):1201-14.
-
(1999)
Int J Radiat Biol.
, vol.75
, Issue.10
, pp. 1201-1214
-
-
Lavin, M.F.1
Khanna, K.K.2
-
12
-
-
59649128916
-
Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death
-
Tian B, Yang Q, Mao Z. Phosphorylation of ATM by Cdk5 mediates DNA damage signalling and regulates neuronal death. Nat Cell Biol. 2009;11(2):211-8.
-
(2009)
Nat Cell Biol.
, vol.11
, Issue.2
, pp. 211-218
-
-
Tian, B.1
Yang, Q.2
Mao, Z.3
-
13
-
-
0024205754
-
Localization of an ataxia-telangiectasia gene to chromosome 11q22-23
-
Gatti RA, Berkel I, Boder E, Braedt G, Charmley P, Concannon P, et al. Localization of an ataxia-telangiectasia gene to chromosome 11q22-23. Nature. 1988;336(6199):577-80.
-
(1988)
Nature.
, vol.336
, Issue.6199
, pp. 577-580
-
-
Gatti, R.A.1
Berkel, I.2
Boder, E.3
Braedt, G.4
Charmley, P.5
Concannon, P.6
-
14
-
-
0034966837
-
Ataxia telangiectasia: New neurons and ATM
-
McKinnon PJ. Ataxia telangiectasia: new neurons and ATM. Trends Mol Med. 2001;7(6):233-4.
-
(2001)
Trends Mol Med.
, vol.7
, Issue.6
, pp. 233-234
-
-
McKinnon, P.J.1
-
15
-
-
0038799736
-
Oxidative DNA damage: Mechanisms, mutation, and disease
-
Cooke MS, Evans MD, Dizdaroglu M, Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. Faseb J. 2003;17(10):1195-214.
-
(2003)
Faseb J.
, vol.17
, Issue.10
, pp. 1195-1214
-
-
Cooke, M.S.1
Evans, M.D.2
Dizdaroglu, M.3
Lunec, J.4
-
16
-
-
0022992181
-
The incidence and gene frequency of ataxia-telangiectasia in the United States
-
Swift M, Morrell D, Cromartie E, Chamberlin AR, Skolnick MH, Bishop DT. The incidence and gene frequency of ataxia-telangiectasia in the United States. Am J Hum Genet. 1986;39(5):573-83.
-
(1986)
Am J Hum Genet.
, vol.39
, Issue.5
, pp. 573-583
-
-
Swift, M.1
Morrell, D.2
Cromartie, E.3
Chamberlin, A.R.4
Skolnick, M.H.5
Bishop, D.T.6
-
17
-
-
0028827312
-
The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species
-
Savitsky K, Sfez S, Tagle DA, Ziv Y, Sartiel A, Collins FS, et al. The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species. Hum Mol Genet. 1995;4(11):2025-32.
-
(1995)
Hum Mol Genet.
, vol.4
, Issue.11
, pp. 2025-2032
-
-
Savitsky, K.1
Sfez, S.2
Tagle, D.A.3
Ziv, Y.4
Sartiel, A.5
Collins, F.S.6
-
18
-
-
84857062467
-
Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: A genotype-phenotype study
-
Verhagen MM, Last JI, Hogervorst FB, Smeets DF, Roeleveld N, Verheijen F, et al. Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: a genotype-phenotype study. Hum Mutat. 2012;33(3):561-71.
-
(2012)
Hum Mutat.
, vol.33
, Issue.3
, pp. 561-571
-
-
Verhagen, M.M.1
Last, J.I.2
Hogervorst, F.B.3
Smeets, D.F.4
Roeleveld, N.5
Verheijen, F.6
-
19
-
-
84857189416
-
Underexpression and abnormal localization of ATM products in ataxia telangiectasia patients bearing ATM missense mutations
-
Jacquemin V, Rieunier G, Jacob S, Bellanger D, d'Enghien CD, Lauge A, et al. Underexpression and abnormal localization of ATM products in ataxia telangiectasia patients bearing ATM missense mutations. Eur J Hum Genet. 2012;20(3):305-12.
-
(2012)
Eur J Hum Genet.
, vol.20
, Issue.3
, pp. 305-312
-
-
Jacquemin, V.1
Rieunier, G.2
Jacob, S.3
Bellanger, D.4
d'Enghien, C.D.5
Lauge, A.6
-
20
-
-
0033617368
-
Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl
-
Chen G, Yuan SS, Liu W, Xu Y, Trujillo K, Song B, et al. Radiation-induced assembly of Rad51 and Rad52 recombination complex requires ATM and c-Abl. J Biol Chem. 1999;274(18):12748-52.
-
(1999)
J Biol Chem.
, vol.274
, Issue.18
, pp. 12748-12752
-
-
Chen, G.1
Yuan, S.S.2
Liu, W.3
Xu, Y.4
Trujillo, K.5
Song, B.6
-
21
-
-
0034665121
-
Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage
-
Chen J. Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage. Cancer Res. 2000;60(18):5037-9.
-
(2000)
Cancer Res.
, vol.60
, Issue.18
, pp. 5037-5039
-
-
Chen, J.1
-
22
-
-
0035844130
-
ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation
-
Chen MJ, Lin YT, Lieberman HB, Chen G, Lee EY. ATM-dependent phosphorylation of human Rad9 is required for ionizing radiation-induced checkpoint activation. J Biol Chem. 2001;276(19):16580-6.
-
(2001)
J Biol Chem.
, vol.276
, Issue.19
, pp. 16580-16586
-
-
Chen, M.J.1
Lin, Y.T.2
Lieberman, H.B.3
Chen, G.4
Lee, E.Y.5
-
23
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to doublestrand breaks
-
Cortez D, Wang Y, Qin J, Elledge SJ. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to doublestrand breaks. Science. 1999;286(5442):1162-6.
-
(1999)
Science.
, vol.286
, Issue.5442
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
24
-
-
0034576494
-
The many substrates and functions of ATM
-
Kastan MB, Lim DS. The many substrates and functions of ATM. Nat Rev Mol Cell Biol. 2000;1(3):179-86.
-
(2000)
Nat Rev Mol Cell Biol.
, vol.1
, Issue.3
, pp. 179-186
-
-
Kastan, M.B.1
Lim, D.S.2
-
25
-
-
0033615547
-
Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase
-
Kim GD, Choi YH, Dimtchev A, Jeong SJ, Dritschilo A, Jung M. Sensing of ionizing radiation-induced DNA damage by ATM through interaction with histone deacetylase. J Biol Chem. 1999;274(44):31127-30.
-
(1999)
J Biol Chem.
, vol.274
, Issue.44
, pp. 31127-31130
-
-
Kim, G.D.1
Choi, Y.H.2
Dimtchev, A.3
Jeong, S.J.4
Dritschilo, A.5
Jung, M.6
-
26
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim ST, Lim DS, Canman CE, Kastan MB. Substrate specificities and identification of putative substrates of ATM kinase family members. J Biol Chem. 1999;274(53):37538-43.
-
(1999)
J Biol Chem.
, vol.274
, Issue.53
, pp. 37538-37543
-
-
Kim, S.T.1
Lim, D.S.2
Canman, C.E.3
Kastan, M.B.4
-
27
-
-
0034644220
-
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
-
Li S, Ting NS, Zheng L, Chen PL, Ziv Y, Shiloh Y, et al. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature. 2000;406(6792):210-5.
-
(2000)
Nature.
, vol.406
, Issue.6792
, pp. 210-215
-
-
Li, S.1
Ting, N.S.2
Zheng, L.3
Chen, P.L.4
Ziv, Y.5
Shiloh, Y.6
-
28
-
-
0034641724
-
Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro
-
Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci USA. 2000;97(19):10389-94.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, Issue.19
, pp. 10389-10394
-
-
Matsuoka, S.1
Rotman, G.2
Ogawa, A.3
Shiloh, Y.4
Tamai, K.5
Elledge, S.J.6
-
29
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem. 1998;273(10):5858-68.
-
(1998)
J Biol Chem.
, vol.273
, Issue.10
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
30
-
-
0030992749
-
Interaction between ATM protein and c-Abl in response to DNA damage
-
Shafman T, Khanna KK, Kedar P, Spring K, Kozlov S, Yen T, et al. Interaction between ATM protein and c-Abl in response to DNA damage. Nature. 1997;387(6632):520-3.
-
(1997)
Nature.
, vol.387
, Issue.6632
, pp. 520-523
-
-
Shafman, T.1
Khanna, K.K.2
Kedar, P.3
Spring, K.4
Kozlov, S.5
Yen, T.6
-
31
-
-
0033520432
-
Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation
-
Suzuki K, Kodama S, Watanabe M. Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. J Biol Chem. 1999;274(36):25571-5.
-
(1999)
J Biol Chem.
, vol.274
, Issue.36
, pp. 25571-25575
-
-
Suzuki, K.1
Kodama, S.2
Watanabe, M.3
-
32
-
-
0030941281
-
Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints
-
Westphal CH, Schmaltz C, Rowan S, Elson A, Fisher DE, Leder P. Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints. Cancer Res. 1997;57(9):1664-7.
-
(1997)
Cancer Res.
, vol.57
, Issue.9
, pp. 1664-1667
-
-
Westphal, C.H.1
Schmaltz, C.2
Rowan, S.3
Elson, A.4
Fisher, D.E.5
Leder, P.6
-
33
-
-
0034713466
-
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
-
Wu X, Ranganathan V, Weisman DS, Heine WF, Ciccone DN, O'Neill TB, et al. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature. 2000;405(6785):477-82.
-
(2000)
Nature.
, vol.405
, Issue.6785
, pp. 477-482
-
-
Wu, X.1
Ranganathan, V.2
Weisman, D.S.3
Heine, W.F.4
Ciccone, D.N.5
O'Neill, T.B.6
-
34
-
-
0034713393
-
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
-
Zhao S, Weng YC, Yuan SS, Lin YT, Hsu HC, Lin SC, et al. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature. 2000;405(6785):473-7.
-
(2000)
Nature.
, vol.405
, Issue.6785
, pp. 473-477
-
-
Zhao, S.1
Weng, Y.C.2
Yuan, S.S.3
Lin, Y.T.4
Hsu, H.C.5
Lin, S.C.6
-
35
-
-
0034142034
-
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites
-
Shieh SY, Ahn J, Tamai K, Taya Y, Prives C. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites. Genes Dev. 2000;14(3):289-300.
-
(2000)
Genes Dev.
, vol.14
, Issue.3
, pp. 289-300
-
-
Shieh, S.Y.1
Ahn, J.2
Tamai, K.3
Taya, Y.4
Prives, C.5
-
36
-
-
0000303499
-
ATM associates with and phosphorylates p53: Mapping the region of interaction
-
Khanna KK, Keating KE, Kozlov S, Scott S, Gatei M, Hobson K, et al. ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet. 1998;20(4):398-400.
-
(1998)
Nat Genet.
, vol.20
, Issue.4
, pp. 398-400
-
-
Khanna, K.K.1
Keating, K.E.2
Kozlov, S.3
Scott, S.4
Gatei, M.5
Hobson, K.6
-
37
-
-
0026549535
-
Heterogeneity in ataxia-telangiectasia: Classical phenotype associated with intermediate cellular radiosensitivity
-
Chessa L, Petrinelli P, Antonelli A, Fiorilli M, Elli R, Marcucci L, et al. Heterogeneity in ataxia-telangiectasia: classical phenotype associated with intermediate cellular radiosensitivity. Am J Med Genet. 1992;42(5):741-6.
-
(1992)
Am J Med Genet.
, vol.42
, Issue.5
, pp. 741-746
-
-
Chessa, L.1
Petrinelli, P.2
Antonelli, A.3
Fiorilli, M.4
Elli, R.5
Marcucci, L.6
-
38
-
-
0022489591
-
Chronic T cell leukemia with unusual cellular characteristics in ataxia telangiectasia
-
Duhrsen U, Uppenkamp M, Uppenkamp I, Becher R, Engelhard M, Konig E, et al. Chronic T cell leukemia with unusual cellular characteristics in ataxia telangiectasia. Blood. 1986;68(2):577-85.
-
(1986)
Blood.
, vol.68
, Issue.2
, pp. 577-585
-
-
Duhrsen, U.1
Uppenkamp, M.2
Uppenkamp, I.3
Becher, R.4
Engelhard, M.5
Konig, E.6
-
39
-
-
0024503816
-
Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line
-
Ziv Y, Jaspers NG, Etkin S, Danieli T, Trakhtenbrot L, Amiel A, et al. Cellular and molecular characteristics of an immortalized ataxia-telangiectasia (group AB) cell line. Cancer Res. 1989;49(9):2495-501.
-
(1989)
Cancer Res.
, vol.49
, Issue.9
, pp. 2495-2501
-
-
Ziv, Y.1
Jaspers, N.G.2
Etkin, S.3
Danieli, T.4
Trakhtenbrot, L.5
Amiel, A.6
-
40
-
-
84862755924
-
Neurodegeneration in ataxia telangiectasia: What is new? What is evident?
-
Hoche F, Seidel K, Theis M, Vlaho S, Schubert R, Zielen S, et al. Neurodegeneration in ataxia telangiectasia: what is new? What is evident? Neuropediatrics. 2012;43(3):119-29.
-
(2012)
Neuropediatrics.
, vol.43
, Issue.3
, pp. 119-129
-
-
Hoche, F.1
Seidel, K.2
Theis, M.3
Vlaho, S.4
Schubert, R.5
Zielen, S.6
-
41
-
-
84860692938
-
Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia
-
Li J, Chen J, Ricupero CL, Hart RP, Schwartz MS, Kusnecov A, et al. Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia. Nat Med. 2012;18(5):783-90.
-
(2012)
Nat Med.
, vol.18
, Issue.5
, pp. 783-790
-
-
Li, J.1
Chen, J.2
Ricupero, C.L.3
Hart, R.P.4
Schwartz, M.S.5
Kusnecov, A.6
-
42
-
-
70449701563
-
Neurodegeneration mediated by chromosome instability suggests changes in strategy for therapy development in ataxia-telangiectasia
-
Yurov YB, Iourov IY, Vorsanova SG. Neurodegeneration mediated by chromosome instability suggests changes in strategy for therapy development in ataxia-telangiectasia. Med Hypotheses. 2009;73(6):1075-6.
-
(2009)
Med Hypotheses.
, vol.73
, Issue.6
, pp. 1075-1076
-
-
Yurov, Y.B.1
Iourov, I.Y.2
Vorsanova, S.G.3
-
43
-
-
0029097511
-
The ataxia-telangiectasia gene: A link between checkpoint controls, neurodegeneration and cancer
-
Lehmann AR, Carr AM. The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer. Trends Genet. 1995;11(10):375-7.
-
(1995)
Trends Genet.
, vol.11
, Issue.10
, pp. 375-377
-
-
Lehmann, A.R.1
Carr, A.M.2
-
44
-
-
0029820057
-
Ataxia-telangiectasia and the ATM gene: Linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints
-
Shiloh Y, Rotman G. Ataxia-telangiectasia and the ATM gene: linking neurodegeneration, immunodeficiency, and cancer to cell cycle checkpoints. J Clin Immunol. 1996;16(5):254-60.
-
(1996)
J Clin Immunol.
, vol.16
, Issue.5
, pp. 254-260
-
-
Shiloh, Y.1
Rotman, G.2
-
45
-
-
44949238447
-
The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
-
Biton S, Barzilai A, Shiloh Y. The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle. DNA Repair (Amst). 2008;7(7):1028-38.
-
(2008)
DNA Repair (Amst).
, vol.7
, Issue.7
, pp. 1028-1038
-
-
Biton, S.1
Barzilai, A.2
Shiloh, Y.3
-
46
-
-
5744246254
-
MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder
-
Delia D, Piane M, Buscemi G, Savio C, Palmeri S, Lulli P, et al. MRE11 mutations and impaired ATM-dependent responses in an Italian family with ataxia-telangiectasia-like disorder. Hum Mol Genet. 2004;13(18):2155-63.
-
(2004)
Hum Mol Genet.
, vol.13
, Issue.18
, pp. 2155-2163
-
-
Delia, D.1
Piane, M.2
Buscemi, G.3
Savio, C.4
Palmeri, S.5
Lulli, P.6
-
47
-
-
3242889151
-
Ataxiatelangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis
-
Taylor AM, Groom A, Byrd PJ. Ataxiatelangiectasia-like disorder (ATLD)-its clinical presentation and molecular basis. DNA Repair (Amst). 2004;3(8-9):1219-25.
-
(2004)
DNA Repair (Amst).
, vol.3
, Issue.8-9
, pp. 1219-1225
-
-
Taylor, A.M.1
Groom, A.2
Byrd, P.J.3
-
48
-
-
0033008552
-
Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts
-
Kraakman-van der Zwet M, Overkamp WJ, Friedl AA, Klein B, Verhaegh GW, Jaspers NG, et al. Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts. Mutat Res. 1999;434(1):17-27.
-
(1999)
Mutat Res.
, vol.434
, Issue.1
, pp. 17-27
-
-
Kraakman-van der Zwet, M.1
Overkamp, W.J.2
Friedl, A.A.3
Klein, B.4
Verhaegh, G.W.5
Jaspers, N.G.6
-
49
-
-
17344372572
-
Positional cloning of the gene for Nijmegen breakage syndrome
-
Matsuura S, Tauchi H, Nakamura A, Kondo N, Sakamoto S, Endo S, et al. Positional cloning of the gene for Nijmegen breakage syndrome. Nat Genet. 1998;19(2):179-81.
-
(1998)
Nat Genet.
, vol.19
, Issue.2
, pp. 179-181
-
-
Matsuura, S.1
Tauchi, H.2
Nakamura, A.3
Kondo, N.4
Sakamoto, S.5
Endo, S.6
-
50
-
-
16944366639
-
The gene for the ataxia-telangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21
-
Saar K, Chrzanowska KH, Stumm M, Jung M, Nurnberg G, Wienker TF, et al. The gene for the ataxia-telangiectasia variant, Nijmegen breakage syndrome, maps to a 1-cM interval on chromosome 8q21. Am J Hum Genet. 1997;60(3):605-10.
-
(1997)
Am J Hum Genet.
, vol.60
, Issue.3
, pp. 605-610
-
-
Saar, K.1
Chrzanowska, K.H.2
Stumm, M.3
Jung, M.4
Nurnberg, G.5
Wienker, T.F.6
-
51
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel T, Lerenthal Y, Moyal L, Andegeko Y, Mittelman L, Shiloh Y. Requirement of the MRN complex for ATM activation by DNA damage. Embo J. 2003;22(20):5612-21.
-
(2003)
Embo J.
, vol.22
, Issue.20
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
52
-
-
78650000995
-
Selective neuronal vulnerability to oxidative stress in the brain
-
Wang X, Michaelis EK. Selective neuronal vulnerability to oxidative stress in the brain. Front Aging Neurosci. 2010;2:12.
-
(2010)
Front Aging Neurosci.
, vol.2
, pp. 12
-
-
Wang, X.1
Michaelis, E.K.2
-
53
-
-
64549158079
-
Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress
-
Wang X, Zaidi A, Pal R, Garrett AS, Braceras R, Chen XW, et al. Genomic and biochemical approaches in the discovery of mechanisms for selective neuronal vulnerability to oxidative stress. BMC Neurosci. 2009;10:12.
-
(2009)
BMC Neurosci.
, vol.10
, pp. 12
-
-
Wang, X.1
Zaidi, A.2
Pal, R.3
Garrett, A.S.4
Braceras, R.5
Chen, X.W.6
-
54
-
-
13444304203
-
Pharmacological manipulation of ataxia-telangiectasia kinase activity as a treatment for Parkinson's disease
-
Edwin Shackelford R, Manuszak RP, Heard SC, Link CJ, Wang S. Pharmacological manipulation of ataxia-telangiectasia kinase activity as a treatment for Parkinson's disease. Med Hypotheses. 2005;64(4):736-41.
-
(2005)
Med Hypotheses.
, vol.64
, Issue.4
, pp. 736-741
-
-
Edwin Shackelford, R.1
Manuszak, R.P.2
Heard, S.C.3
Link, C.J.4
Wang, S.5
-
55
-
-
1242292303
-
Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans
-
Mawrin C, Kirches E, Krause G, Schneider-Stock R, Bogerts B, Vorwerk CK, et al. Region-specific analysis of mitochondrial DNA deletions in neurodegenerative disorders in humans. Neurosci Lett. 2004;357(2):111-4.
-
(2004)
Neurosci Lett.
, vol.357
, Issue.2
, pp. 111-114
-
-
Mawrin, C.1
Kirches, E.2
Krause, G.3
Schneider-Stock, R.4
Bogerts, B.5
Vorwerk, C.K.6
-
56
-
-
78650033889
-
DNA damage, neuronal and glial cell death and neurodegeneration
-
Barzilai A. DNA damage, neuronal and glial cell death and neurodegeneration. Apoptosis. 2010;15(11):1371-81.
-
(2010)
Apoptosis.
, vol.15
, Issue.11
, pp. 1371-1381
-
-
Barzilai, A.1
-
57
-
-
0042734979
-
Low thymic output and reduced heterogeneity of alpha/beta, but not gamma/delta, T lymphocytes in infants with ataxia-telangiectasia
-
Micheli R, Pirovano S, Calandra G, Valotti M, Plebani A, Albertini A, et al. Low thymic output and reduced heterogeneity of alpha/beta, but not gamma/delta, T lymphocytes in infants with ataxia-telangiectasia. Neuropediatrics. 2003;34(3):165-7.
-
(2003)
Neuropediatrics.
, vol.34
, Issue.3
, pp. 165-167
-
-
Micheli, R.1
Pirovano, S.2
Calandra, G.3
Valotti, M.4
Plebani, A.5
Albertini, A.6
-
58
-
-
0036891869
-
Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia
-
Giovannetti A, Mazzetta F, Caprini E, Aiuti A, Marziali M, Pierdominici M, et al. Skewed T-cell receptor repertoire, decreased thymic output, and predominance of terminally differentiated T cells in ataxia telangiectasia. Blood. 2002;100(12):4082-9.
-
(2002)
Blood.
, vol.100
, Issue.12
, pp. 4082-4089
-
-
Giovannetti, A.1
Mazzetta, F.2
Caprini, E.3
Aiuti, A.4
Marziali, M.5
Pierdominici, M.6
-
59
-
-
0037273702
-
Diversity of the cadherin-related neuronal receptor/protocadherin family and possible DNA rearrangement in the brain
-
Yagi T. Diversity of the cadherin-related neuronal receptor/protocadherin family and possible DNA rearrangement in the brain. Genes Cells. 2003;8(1):1-8.
-
(2003)
Genes Cells.
, vol.8
, Issue.1
, pp. 1-8
-
-
Yagi, T.1
-
60
-
-
0034769473
-
The cadherin-related neuronal receptor family: A novel diversified cadherin family at the synapse
-
Hamada S, Yagi T. The cadherin-related neuronal receptor family: a novel diversified cadherin family at the synapse. Neurosci Res. 2001;41(3):207-15.
-
(2001)
Neurosci Res.
, vol.41
, Issue.3
, pp. 207-215
-
-
Hamada, S.1
Yagi, T.2
-
61
-
-
0035065823
-
Somatic mutations of synaptic cadherin (CNR family) transcripts in the nervous system
-
Hirayama T, Sugino H, Yagi T. Somatic mutations of synaptic cadherin (CNR family) transcripts in the nervous system. Genes Cells. 2001;6(2):151-64.
-
(2001)
Genes Cells.
, vol.6
, Issue.2
, pp. 151-164
-
-
Hirayama, T.1
Sugino, H.2
Yagi, T.3
-
62
-
-
0032585526
-
Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
-
Barnes DE, Stamp G, Rosewell I, Denzel A, Lindahl T. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr Biol. 1998;8(25):1395-8.
-
(1998)
Curr Biol.
, vol.8
, Issue.25
, pp. 1395-1398
-
-
Barnes, D.E.1
Stamp, G.2
Rosewell, I.3
Denzel, A.4
Lindahl, T.5
-
63
-
-
0032511976
-
Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
-
Frank KM, Sekiguchi JM, Seidl KJ, Swat W, Rathbun GA, Cheng HL, et al. Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV. Nature. 1998;396(6707):173-7.
-
(1998)
Nature.
, vol.396
, Issue.6707
, pp. 173-177
-
-
Frank, K.M.1
Sekiguchi, J.M.2
Seidl, K.J.3
Swat, W.4
Rathbun, G.A.5
Cheng, H.L.6
-
64
-
-
0033634973
-
DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway
-
Frank KM, Sharpless NE, Gao Y, Sekiguchi JM, Ferguson DO, Zhu C, et al. DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway. Mol Cell. 2000;5(6):993-1002.
-
(2000)
Mol Cell.
, vol.5
, Issue.6
, pp. 993-1002
-
-
Frank, K.M.1
Sharpless, N.E.2
Gao, Y.3
Sekiguchi, J.M.4
Ferguson, D.O.5
Zhu, C.6
-
65
-
-
79953721149
-
Cytoplasmic ATM protein kinase: An emerging therapeutic target for diabetes, cancer and neuronal degeneration
-
Yang DQ, Halaby MJ, Li Y, Hibma JC, Burn P. Cytoplasmic ATM protein kinase: an emerging therapeutic target for diabetes, cancer and neuronal degeneration. Drug Discov Today. 2011;16(7-8):332-8.
-
(2011)
Drug Discov Today.
, vol.16
, Issue.7-8
, pp. 332-338
-
-
Yang, D.Q.1
Halaby, M.J.2
Li, Y.3
Hibma, J.C.4
Burn, P.5
-
66
-
-
77957333810
-
A cytoplasmic ATMTRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NFkappaB activation
-
Hinz M, Stilmann M, Arslan SC, Khanna KK, Dittmar G, Scheidereit C. A cytoplasmic ATMTRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NFkappaB activation. Mol Cell. 2010;40(1):63-74.
-
(2010)
Mol Cell.
, vol.40
, Issue.1
, pp. 63-74
-
-
Hinz, M.1
Stilmann, M.2
Arslan, S.C.3
Khanna, K.K.4
Dittmar, G.5
Scheidereit, C.6
-
67
-
-
72449147303
-
Cytoplasmic ATM in neurons modulates synaptic function
-
Li J, Han YR, Plummer MR, Herrup K. Cytoplasmic ATM in neurons modulates synaptic function. Curr Biol. 2009;19(24):2091-6.
-
(2009)
Curr Biol.
, vol.19
, Issue.24
, pp. 2091-2096
-
-
Li, J.1
Han, Y.R.2
Plummer, M.R.3
Herrup, K.4
-
68
-
-
33845742491
-
Constitutive expression and cytoplasmic compartmentalization of ATM protein in differentiated human neuron-like SH-SY5Y cells
-
Boehrs JK, He J, Halaby MJ, Yang DQ. Constitutive expression and cytoplasmic compartmentalization of ATM protein in differentiated human neuron-like SH-SY5Y cells. J Neurochem. 2007;100(2):337-45.
-
(2007)
J Neurochem.
, vol.100
, Issue.2
, pp. 337-345
-
-
Boehrs, J.K.1
He, J.2
Halaby, M.J.3
Yang, D.Q.4
-
69
-
-
12944316603
-
ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation
-
Barlow C, Ribaut-Barassin C, Zwingman TA, Pope AJ, Brown KD, Owens JW, et al. ATM is a cytoplasmic protein in mouse brain required to prevent lysosomal accumulation. Proc Natl Acad Sci USA. 2000;97(2):871-6.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, Issue.2
, pp. 871-876
-
-
Barlow, C.1
Ribaut-Barassin, C.2
Zwingman, T.A.3
Pope, A.J.4
Brown, K.D.5
Owens, J.W.6
-
70
-
-
0032544038
-
ATM binds to betaadaptin in cytoplasmic vesicles
-
Lim DS, Kirsch DG, Canman CE, Ahn JH, Ziv Y, Newman LS, et al. ATM binds to betaadaptin in cytoplasmic vesicles. Proc Natl Acad Sci USA. 1998;95(17):10146-51.
-
(1998)
Proc Natl Acad Sci USA.
, vol.95
, Issue.17
, pp. 10146-10151
-
-
Lim, D.S.1
Kirsch, D.G.2
Canman, C.E.3
Ahn, J.H.4
Ziv, Y.5
Newman, L.S.6
-
71
-
-
44349184864
-
Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation
-
Fu X, Wan S, Lyu YL, Liu LF, Qi H. Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation. PLoS One. 2008;3(4):e2009.
-
(2008)
PLoS One.
, vol.3
, Issue.4
-
-
Fu, X.1
Wan, S.2
Lyu, Y.L.3
Liu, L.F.4
Qi, H.5
-
72
-
-
84865183979
-
Functional switching of ATM: Sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells
-
Li Y, Xiong H, Yang DQ. Functional switching of ATM: sensor of DNA damage in proliferating cells and mediator of Akt survival signal in post-mitotic human neuron-like cells. Chin J Cancer. 2012;31(3):364-72.
-
(2012)
Chin J Cancer.
, vol.31
, Issue.3
, pp. 364-372
-
-
Li, Y.1
Xiong, H.2
Yang, D.Q.3
-
73
-
-
78649262870
-
The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress
-
Kim TS, Kawaguchi M, Suzuki M, Jung CG, Asai K, Shibamoto Y, et al. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Dis Model Mech. 2010;3(11-12):752-62.
-
(2010)
Dis Model Mech.
, vol.3
, Issue.11-12
, pp. 752-762
-
-
Kim, T.S.1
Kawaguchi, M.2
Suzuki, M.3
Jung, C.G.4
Asai, K.5
Shibamoto, Y.6
-
74
-
-
13244249527
-
Why do neurons enter the cell cycle?
-
Kruman II. Why do neurons enter the cell cycle? Cell Cycle. 2004;3(6):769-73.
-
(2004)
Cell Cycle.
, vol.3
, Issue.6
, pp. 769-773
-
-
Kruman, I.I.1
-
75
-
-
1342333775
-
Cell cycle activation linked to neuronal cell death initiated by DNA damage
-
Kruman II, Wersto RP, Cardozo-Pelaez F, Smilenov L, Chan SL, Chrest FJ, et al. Cell cycle activation linked to neuronal cell death initiated by DNA damage. Neuron. 2004;41(4):549-61.
-
(2004)
Neuron.
, vol.41
, Issue.4
, pp. 549-561
-
-
Kruman, I.I.1
Wersto, R.P.2
Cardozo-Pelaez, F.3
Smilenov, L.4
Chan, S.L.5
Chrest, F.J.6
-
76
-
-
0031992159
-
E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2
-
Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ. 1998;9(2):113-8.
-
(1998)
Cell Growth Differ.
, vol.9
, Issue.2
, pp. 113-118
-
-
Kowalik, T.F.1
DeGregori, J.2
Leone, G.3
Jakoi, L.4
Nevins, J.R.5
-
77
-
-
0028960617
-
E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
-
Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol. 1995;69(4):2491-500.
-
(1995)
J Virol.
, vol.69
, Issue.4
, pp. 2491-2500
-
-
Kowalik, T.F.1
DeGregori, J.2
Schwarz, J.K.3
Nevins, J.R.4
-
79
-
-
73849112948
-
From birth till death: Neurogenesis, cell cycle, and neurodegeneration
-
Demir O, Singh S, Klimaschewski L, Kurnaz IA. From birth till death: neurogenesis, cell cycle, and neurodegeneration. Anat Rec (Hoboken). 2009;292(12):1953-61.
-
(2009)
Anat Rec (Hoboken).
, vol.292
, Issue.12
, pp. 1953-1961
-
-
Demir, O.1
Singh, S.2
Klimaschewski, L.3
Kurnaz, I.A.4
-
80
-
-
77951685246
-
Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain
-
Soriano SG, Liu Q, Li J, Liu JR, Han XH, Kanter JL, et al. Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brain. Anesthesiology. 2010;112(5):1155-63.
-
(2010)
Anesthesiology.
, vol.112
, Issue.5
, pp. 1155-1163
-
-
Soriano, S.G.1
Liu, Q.2
Li, J.3
Liu, J.R.4
Han, X.H.5
Kanter, J.L.6
-
81
-
-
35848936298
-
Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the Atm/p53/E2F-1 path in cerebellar granule neurons
-
Alvira D, Yeste-Velasco M, Folch J, Casadesus G, Smith MA, Pallas M, et al. Neuroprotective effects of caffeine against complex I inhibition-induced apoptosis are mediated by inhibition of the Atm/p53/E2F-1 path in cerebellar granule neurons. J Neurosci Res. 2007;85(14):3079-88.
-
(2007)
J Neurosci Res.
, vol.85
, Issue.14
, pp. 3079-3088
-
-
Alvira, D.1
Yeste-Velasco, M.2
Folch, J.3
Casadesus, G.4
Smith, M.A.5
Pallas, M.6
-
82
-
-
15844426692
-
Atm-deficient mice: A paradigm of ataxia telangiectasia
-
Barlow C, Hirotsune S, Paylor R, Liyanage M, Eckhaus M, Collins F, et al. Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell. 1996;86(1):159-71.
-
(1996)
Cell.
, vol.86
, Issue.1
, pp. 159-171
-
-
Barlow, C.1
Hirotsune, S.2
Paylor, R.3
Liyanage, M.4
Eckhaus, M.5
Collins, F.6
-
83
-
-
0029848286
-
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
-
Elson A, Wang Y, Daugherty CJ, Morton CC, Zhou F, Campos-Torres J, et al. Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci USA. 1996;93(23):13084-9.
-
(1996)
Proc Natl Acad Sci USA.
, vol.93
, Issue.23
, pp. 13084-13089
-
-
Elson, A.1
Wang, Y.2
Daugherty, C.J.3
Morton, C.C.4
Zhou, F.5
Campos-Torres, J.6
-
84
-
-
0029844048
-
Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma
-
Xu Y, Ashley T, Brainerd EE, Bronson RT, Meyn MS, Baltimore D. Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev. 1996;10(19):2411-22.
-
(1996)
Genes Dev.
, vol.10
, Issue.19
, pp. 2411-2422
-
-
Xu, Y.1
Ashley, T.2
Brainerd, E.E.3
Bronson, R.T.4
Meyn, M.S.5
Baltimore, D.6
-
85
-
-
0029821651
-
Dual roles of ATM in the cellular response to radiation and in cell growth control
-
Xu Y, Baltimore D. Dual roles of ATM in the cellular response to radiation and in cell growth control. Genes Dev. 1996;10(19):2401-10.
-
(1996)
Genes Dev.
, vol.10
, Issue.19
, pp. 2401-2410
-
-
Xu, Y.1
Baltimore, D.2
-
86
-
-
0033578411
-
Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs
-
Barlow C, Dennery PA, Shigenaga MK, Smith MA, Morrow JD, Roberts LJ 2nd, et al. Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci USA. 1999;96(17):9915-9.
-
(1999)
Proc Natl Acad Sci USA.
, vol.96
, Issue.17
, pp. 9915-9919
-
-
Barlow, C.1
Dennery, P.A.2
Shigenaga, M.K.3
Smith, M.A.4
Morrow, J.D.5
Roberts II, L.J.6
-
87
-
-
12944328742
-
Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice
-
Borghesani PR, Alt FW, Bottaro A, Davidson L, Aksoy S, Rathbun GA, et al. Abnormal development of Purkinje cells and lymphocytes in Atm mutant mice. Proc Natl Acad Sci USA. 2000;97(7):3336-41.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, Issue.7
, pp. 3336-3341
-
-
Borghesani, P.R.1
Alt, F.W.2
Bottaro, A.3
Davidson, L.4
Aksoy, S.5
Rathbun, G.A.6
-
88
-
-
0037016764
-
Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice
-
Stern N, Hochman A, Zemach N, Weizman N, Hammel I, Shiloh Y, et al. Accumulation of DNA damage and reduced levels of nicotine adenine dinucleotide in the brains of Atm-deficient mice. J Biol Chem. 2002;277(1):602-8.
-
(2002)
J Biol Chem.
, vol.277
, Issue.1
, pp. 602-608
-
-
Stern, N.1
Hochman, A.2
Zemach, N.3
Weizman, N.4
Hammel, I.5
Shiloh, Y.6
-
89
-
-
84856673305
-
Activation of AMP-activated protein kinase in cerebella of Atm-/-mice is attributable to accumulation of reactive oxygen species
-
Kuang X, Yan M, Ajmo JM, Scofield VL, Stoica G, Wong PK. Activation of AMP-activated protein kinase in cerebella of Atm-/-mice is attributable to accumulation of reactive oxygen species. Biochem Biophys Res Commun. 2012;418(2):267-72.
-
(2012)
Biochem Biophys Res Commun.
, vol.418
, Issue.2
, pp. 267-272
-
-
Kuang, X.1
Yan, M.2
Ajmo, J.M.3
Scofield, V.L.4
Stoica, G.5
Wong, P.K.6
-
90
-
-
0035281565
-
Ataxia telangiectasia mutated is essential during adult neurogenesis
-
Allen DM, van Praag H, Ray J, Weaver Z, Winrow CJ, Carter TA, et al. Ataxia telangiectasia mutated is essential during adult neurogenesis. Genes Dev. 2001;15(5):554-66.
-
(2001)
Genes Dev.
, vol.15
, Issue.5
, pp. 554-566
-
-
Allen, D.M.1
van Praag, H.2
Ray, J.3
Weaver, Z.4
Winrow, C.J.5
Carter, T.A.6
-
91
-
-
0035282711
-
Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia
-
Hande MP, Balajee AS, Tchirkov A, Wynshaw-Boris A, Lansdorp PM. Extra-chromosomal telomeric DNA in cells from Atm(-/-) mice and patients with ataxia-telangiectasia. Hum Mol Genet. 2001;10(5):519-28.
-
(2001)
Hum Mol Genet.
, vol.10
, Issue.5
, pp. 519-528
-
-
Hande, M.P.1
Balajee, A.S.2
Tchirkov, A.3
Wynshaw-Boris, A.4
Lansdorp, P.M.5
-
92
-
-
0037421896
-
Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing
-
Wong KK, Maser RS, Bachoo RM, Menon J, Carrasco DR, Gu Y, et al. Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing. Nature. 2003;421(6923):643-8.
-
(2003)
Nature.
, vol.421
, Issue.6923
, pp. 643-648
-
-
Wong, K.K.1
Maser, R.S.2
Bachoo, R.M.3
Menon, J.4
Carrasco, D.R.5
Gu, Y.6
-
93
-
-
0034013797
-
The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast
-
Ritchie KB, Petes TD. The Mre11p/Rad50p/Xrs2p complex and the Tel1p function in a single pathway for telomere maintenance in yeast. Genetics. 2000;155(1):475-9.
-
(2000)
Genetics.
, vol.155
, Issue.1
, pp. 475-479
-
-
Ritchie, K.B.1
Petes, T.D.2
-
94
-
-
4143123447
-
ATM is required for telomere maintenance and chromosome stability during Drosophila development
-
Silva E, Tiong S, Pedersen M, Homola E, Royou A, Fasulo B, et al. ATM is required for telomere maintenance and chromosome stability during Drosophila development. Curr Biol. 2004;14(15):1341-7.
-
(2004)
Curr Biol.
, vol.14
, Issue.15
, pp. 1341-1347
-
-
Silva, E.1
Tiong, S.2
Pedersen, M.3
Homola, E.4
Royou, A.5
Fasulo, B.6
-
95
-
-
0035036503
-
A mutation that causes telomere fusion and severe genome rearrangements in Drosophila melanogaster
-
Queiroz-Machado J, Perdigao J, Simoes-Carvalho P, Herrmann S, Sunkel CE. tef: a mutation that causes telomere fusion and severe genome rearrangements in Drosophila melanogaster. Chromosoma. 2001;110(1):10-23.
-
(2001)
Chromosoma.
, vol.110
, Issue.1
, pp. 10-23
-
-
Queiroz-Machado, J.1
Perdigao, J.2
Simoes-Carvalho, P.3
Herrmann, S.4
Sunkel, C.E.5
-
96
-
-
84858264276
-
ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila
-
Petersen AJ, Rimkus SA, Wassarman DA. ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila. Proc Natl Acad Sci USA. 2012;109(11):E656-64.
-
(2012)
Proc Natl Acad Sci USA.
, vol.109
, Issue.11
-
-
Petersen, A.J.1
Rimkus, S.A.2
Wassarman, D.A.3
-
97
-
-
41549152936
-
Zebrafish as a model system to screen radiation modifiers
-
Hwang M, Yong C, Moretti L, Lu B. Zebrafish as a model system to screen radiation modifiers. Curr Genomics. 2007;8(6):360-9.
-
(2007)
Curr Genomics.
, vol.8
, Issue.6
, pp. 360-369
-
-
Hwang, M.1
Yong, C.2
Moretti, L.3
Lu, B.4
-
98
-
-
14644416590
-
Molecular cloning and functional characterization of zebrafish ATM
-
Imamura S, Kishi S. Molecular cloning and functional characterization of zebrafish ATM. Int J Biochem Cell Biol. 2005;37(5):1105-16.
-
(2005)
Int J Biochem Cell Biol.
, vol.37
, Issue.5
, pp. 1105-1116
-
-
Imamura, S.1
Kishi, S.2
-
99
-
-
80054907496
-
Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model
-
Galron R, Gruber R, Lifshitz V, Lu H, Kirshner M, Ziv N, et al. Astrocyte dysfunction associated with cerebellar attrition in a Nijmegen breakage syndrome animal model. J Mol Neurosci. 2011;45(2):202-11.
-
(2011)
J Mol Neurosci.
, vol.45
, Issue.2
, pp. 202-211
-
-
Galron, R.1
Gruber, R.2
Lifshitz, V.3
Lu, H.4
Kirshner, M.5
Ziv, N.6
-
100
-
-
67349181294
-
Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system
-
Baranes K, Raz-Prag D, Nitzan A, Galron R, Ashery-Padan R, Rotenstreich Y, et al. Conditional inactivation of the NBS1 gene in the mouse central nervous system leads to neurodegeneration and disorganization of the visual system. Exp Neurol. 2009;218(1):24-32.
-
(2009)
Exp Neurol.
, vol.218
, Issue.1
, pp. 24-32
-
-
Baranes, K.1
Raz-Prag, D.2
Nitzan, A.3
Galron, R.4
Ashery-Padan, R.5
Rotenstreich, Y.6
-
101
-
-
0142123580
-
Late degeneration of nigro-striatal neurons in ATM-/-mice
-
Eilam R, Peter Y, Groner Y, Segal M. Late degeneration of nigro-striatal neurons in ATM-/-mice. Neuroscience. 2003;121(1):83-98.
-
(2003)
Neuroscience.
, vol.121
, Issue.1
, pp. 83-98
-
-
Eilam, R.1
Peter, Y.2
Groner, Y.3
Segal, M.4
-
102
-
-
84866459934
-
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice
-
Yamamoto K, Wang Y, Jiang W, Liu X, Dubois RL, Lin CS, et al. Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. J Cell Biol. 2012;198(3):305-13.
-
(2012)
J Cell Biol.
, vol.198
, Issue.3
, pp. 305-313
-
-
Yamamoto, K.1
Wang, Y.2
Jiang, W.3
Liu, X.4
Dubois, R.L.5
Lin, C.S.6
-
103
-
-
84866445314
-
Loss of ATM kinase activity leads to embryonic lethality in mice
-
Daniel JA, Pellegrini M, Lee BS, Guo Z, Filsuf D, Belkina NV, et al. Loss of ATM kinase activity leads to embryonic lethality in mice. J Cell Biol. 2012;198(3):295-304.
-
(2012)
J Cell Biol.
, vol.198
, Issue.3
, pp. 295-304
-
-
Daniel, J.A.1
Pellegrini, M.2
Lee, B.S.3
Guo, Z.4
Filsuf, D.5
Belkina, N.V.6
-
104
-
-
0033662156
-
Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1
-
Yang DQ, Kastan MB. Participation of ATM in insulin signalling through phosphorylation of eIF-4E-binding protein 1. Nat Cell Biol. 2000;2(12):893-8.
-
(2000)
Nat Cell Biol.
, vol.2
, Issue.12
, pp. 893-898
-
-
Yang, D.Q.1
Kastan, M.B.2
-
105
-
-
0034681136
-
Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system
-
Chong MJ, Murray MR, Gosink EC, Russell HR, Srinivasan A, Kapsetaki M, et al. Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system. Proc Natl Acad Sci USA. 2000;97(2):889-94.
-
(2000)
Proc Natl Acad Sci USA.
, vol.97
, Issue.2
, pp. 889-894
-
-
Chong, M.J.1
Murray, M.R.2
Gosink, E.C.3
Russell, H.R.4
Srinivasan, A.5
Kapsetaki, M.6
-
106
-
-
0030730292
-
Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia-telangiectasia
-
Kuljis RO, Xu Y, Aguila MC, Baltimore D. Degeneration of neurons, synapses, and neuropil and glial activation in a murine Atm knockout model of ataxia-telangiectasia. Proc Natl Acad Sci USA. 1997;94(23):12688-93.
-
(1997)
Proc Natl Acad Sci USA.
, vol.94
, Issue.23
, pp. 12688-12693
-
-
Kuljis, R.O.1
Xu, Y.2
Aguila, M.C.3
Baltimore, D.4
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