Functional switching of ATM: Sensor of DNA damage in proliferating cells and mediator of Akt survival signal post-mitotic human neuron-like cells

Chinese Journal of Cancer

Volumn 31, Issue 8, 2012, Pages 364-372

  Li, Yan ^a   Xiong, Hua ^a   Yang, Da Qing ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Akt; ATM; DNA damage; Neuronal degeneration; Neuronal differentiation

Indexed keywords

ATM PROTEIN; CAMPTOTHECIN; DNA; ETOPOSIDE; HISTONE H2AX; PROTEIN KINASE B; PROTEIN P53;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; ATAXIA TELANGIECTASIA; CELL PROLIFERATION; CELL SPECIFICITY; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; MITOSIS; NERVE CELL DIFFERENTIATION; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NEUROPROTECTION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; ATAXIA TELANGIECTASIA; CAMPTOTHECIN; CELL CYCLE PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; ETOPOSIDE; HISTONES; HUMANS; MORPHOLINES; NEUROBLASTOMA; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PYRONES; SIGNAL TRANSDUCTION; TOPOISOMERASE INHIBITORS; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 84865183979     PISSN: 1000467X     EISSN: 1944446X     Source Type: Journal    
DOI: 10.5732/cjc.012.10086     Document Type: Article

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