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Volumn 3, Issue 6, 2004, Pages 767-771

Why do neurons enter the cell cycle?

Author keywords

Apoptosis; Cell cycle; DNA damage; DNA repair

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTIOXIDANT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; ATM PROTEIN; ATR PROTEIN; CASPASE; CELL NUCLEUS DNA; CHECKPOINT KINASE 2; CYCLIN D; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); MITOCHONDRIAL DNA; OXYGEN RADICAL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN MDM2; PROTEIN P107; PROTEIN P130; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR E2F1;

EID: 13244249527     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.3.6.901     Document Type: Review
Times cited : (87)

References (96)
  • 1
    • 0027278557 scopus 로고
    • Instability and decay of the primary structure of DNA
    • Lindahl T. Instability and decay of the primary structure of DNA. Nature 1993; 362:709-15.
    • (1993) Nature , vol.362 , pp. 709-715
    • Lindahl, T.1
  • 2
    • 0037829284 scopus 로고    scopus 로고
    • Checkpoint signaling: Epigenetic events sound the DNA strand-breaks alarm to the ATM protein kinase
    • Abraham RT. Checkpoint signaling: Epigenetic events sound the DNA strand-breaks alarm to the ATM protein kinase. Bioessays 2003; 25:627-30.
    • (2003) Bioessays , vol.25 , pp. 627-630
    • Abraham, R.T.1
  • 3
    • 0344585940 scopus 로고    scopus 로고
    • The interacting pathways for prevention and repair of oxidative DNA damage
    • Slupphaug G, Kavli B, Krokan HE. The interacting pathways for prevention and repair of oxidative DNA damage. Mutat Res 2003; 531:231-51.
    • (2003) Mutat Res , vol.531 , pp. 231-251
    • Slupphaug, G.1    Kavli, B.2    Krokan, H.E.3
  • 4
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15:2177-96.
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 5
    • 0036270993 scopus 로고    scopus 로고
    • DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis
    • Bernstein C, Bernstein H, Payne CM, Garewal H. DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: Fail-safe protection against carcinogenesis. Mutat Res 2002; 511:145-78.
    • (2002) Mutat Res , vol.511 , pp. 145-178
    • Bernstein, C.1    Bernstein, H.2    Payne, C.M.3    Garewal, H.4
  • 6
    • 0034600975 scopus 로고    scopus 로고
    • Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells
    • Johnson RD, Jasin M. Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells. EMBO J 2000; 19:3398-407.
    • (2000) EMBO J , vol.19 , pp. 3398-3407
    • Johnson, R.D.1    Jasin, M.2
  • 9
    • 0037150731 scopus 로고    scopus 로고
    • The genetics of the E2F family of transcription factors: Shared functions and unique roles
    • DeGregori J. The genetics of the E2F family of transcription factors:Shared functions and unique roles. Biochim Biophys Acta 2002; 1602:131-50.
    • (2002) Biochim Biophys Acta , vol.1602 , pp. 131-150
    • DeGregori, J.1
  • 10
    • 0034636583 scopus 로고    scopus 로고
    • Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb
    • O'Connor DJ, Lu X. Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb. Oncogene 2000; 19:2369-76.
    • (2000) Oncogene , vol.19 , pp. 2369-2376
    • O'Connor, D.J.1    Lu, X.2
  • 11
    • 0032939925 scopus 로고    scopus 로고
    • Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53
    • Blattner C, Sparks A, Lane D. Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol Cell Biol 1999; 19:3704-13.
    • (1999) Mol Cell Biol , vol.19 , pp. 3704-3713
    • Blattner, C.1    Sparks, A.2    Lane, D.3
  • 12
    • 0345299171 scopus 로고    scopus 로고
    • Increased levels of E2F-1-dependent DNA binding activity after UV- Or gamma-irradiation
    • Hofferer M, Wirbelauer C, Humar B, Krek W. Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res 1999; 27:491-5.
    • (1999) Nucleic Acids Res , vol.27 , pp. 491-495
    • Hofferer, M.1    Wirbelauer, C.2    Humar, B.3    Krek, W.4
  • 13
    • 0032622050 scopus 로고    scopus 로고
    • p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin
    • Meng RD, Phillips P, El-Deiry WS. p53-independent increase in E2F-1 expression enhances the cytotoxic effects of etoposide and of adriamycin. Int J Oncol 1999; 14:5-14.
    • (1999) Int J Oncol , vol.14 , pp. 5-14
    • Meng, R.D.1    Phillips, P.2    El-Deiry, W.S.3
  • 14
    • 0034306996 scopus 로고    scopus 로고
    • The Rb/E2F pathway: Expanding roles and emerging paradigms
    • Harbour JW, Dean DC. The Rb/E2F pathway:Expanding roles and emerging paradigms. Genes Dev 2000; 14:2393-409.
    • (2000) Genes Dev , vol.14 , pp. 2393-2409
    • Harbour, J.W.1    Dean, D.C.2
  • 15
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 1995; 81:323-30.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 16
    • 0035829650 scopus 로고    scopus 로고
    • Regulation of neuronal survival and death by E2F-dependent gene repression and derepression
    • Liu DX, Greene LA. Regulation of neuronal survival and death by E2F-dependent gene repression and derepression. Neuron 2001; 32:425-38.
    • (2001) Neuron , vol.32 , pp. 425-438
    • Liu, D.X.1    Greene, L.A.2
  • 18
    • 0034949169 scopus 로고    scopus 로고
    • Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis
    • Ishida S, Huang E, Zuzan H, Spang R, Leone G, West M, et al. Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis Mol Cell Biol 2001; 21:4684-99.
    • (2001) Mol Cell Biol , vol.21 , pp. 4684-4699
    • Ishida, S.1    Huang, E.2    Zuzan, H.3    Spang, R.4    Leone, G.5    West, M.6
  • 19
    • 85047699837 scopus 로고    scopus 로고
    • E2Fs up-regulate expression of genes Involved in DNA replication, DNA repair and mitosis
    • Polager S, Kalma Y, Berkovich E, Ginsberg D. E2Fs up-regulate expression of genes Involved in DNA replication, DNA repair and mitosis. Oncogene 2002; 21:437-46.
    • (2002) Oncogene , vol.21 , pp. 437-446
    • Polager, S.1    Kalma, Y.2    Berkovich, E.3    Ginsberg, D.4
  • 21
    • 0037448689 scopus 로고    scopus 로고
    • ATM is a target for positive regulation by E2F-1
    • Berkovich E, Ginsberg D. ATM is a target for positive regulation by E2F-1. Oncogene 2003; 22:161-7.
    • (2003) Oncogene , vol.22 , pp. 161-167
    • Berkovich, E.1    Ginsberg, D.2
  • 22
    • 2342640317 scopus 로고    scopus 로고
    • A new role for E2F-1 in checkpoint control
    • Stevens C, LaThangue NB. A new role for E2F-1 in checkpoint control. Cell Cycle 2003; 2:435-7.
    • (2003) Cell Cycle , vol.2 , pp. 435-437
    • Stevens, C.1    Lathangue, N.B.2
  • 23
    • 0037080674 scopus 로고    scopus 로고
    • Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis
    • Weinmann AS, Yan PS, Oberley MJ, Huang TH, Farnham PJ. Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis. Genes Dev 2002; 16:235-44.
    • (2002) Genes Dev , vol.16 , pp. 235-244
    • Weinmann, A.S.1    Yan, P.S.2    Oberley, M.J.3    Huang, T.H.4    Farnham, P.J.5
  • 24
    • 0029011805 scopus 로고
    • Cell cycle and apoptosis: Common pathways to life and death
    • King KL, Cidlowski JA. Cell cycle and apoptosis:Common pathways to life and death. J Cell Biochem 1995; 58:175-80.
    • (1995) J Cell Biochem , vol.58 , pp. 175-180
    • King, K.L.1    Cidlowski, J.A.2
  • 25
    • 0036897835 scopus 로고    scopus 로고
    • A revised picture of the E2F transcriptional network and RB function
    • Stevaux O, Dyson NJ. A revised picture of the E2F transcriptional network and RB function. Curr Opin Cell Biol 2002; 14:684-91.
    • (2002) Curr Opin Cell Biol , vol.14 , pp. 684-691
    • Stevaux, O.1    Dyson, N.J.2
  • 27
    • 0034818446 scopus 로고    scopus 로고
    • Post-translational modifications and activation of p53 by genotoxic stresses
    • Appella E, Anderson CW. Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem 2001; 268:2764-72.
    • (2001) Eur J Biochem , vol.268 , pp. 2764-2772
    • Appella, E.1    Anderson, C.W.2
  • 28
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases:Safeguarding genome integrity. Nat Rev Cancer 2003; 3:155-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 30
  • 31
    • 0028960617 scopus 로고
    • E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis
    • Kowalik TF, DeGregori J, Schwarz JK, Nevins JR. E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis. J Virol 1995; 69:2491-500.
    • (1995) J Virol , vol.69 , pp. 2491-2500
    • Kowalik, T.F.1    DeGregori, J.2    Schwarz, J.K.3    Nevins, J.R.4
  • 32
    • 0742281300 scopus 로고    scopus 로고
    • E2F1 and c-Myc in cell growth and death
    • Matsumura I, Tanaka H, Kanakura Y. E2F1 and c-Myc in cell growth and death. Cell Cycle 2003; 2:333-8.
    • (2003) Cell Cycle , vol.2 , pp. 333-338
    • Matsumura, I.1    Tanaka, H.2    Kanakura, Y.3
  • 35
    • 0842278331 scopus 로고    scopus 로고
    • Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis
    • Chipuk JE, Kuwana T, Bouchier-Hayes L, Droin NM, Newmeyer DD, Schuler M, et al. Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science 2004; 303:1010-4.
    • (2004) Science , vol.303 , pp. 1010-1014
    • Chipuk, J.E.1    Kuwana, T.2    Bouchier-Hayes, L.3    Droin, N.M.4    Newmeyer, D.D.5    Schuler, M.6
  • 38
    • 0034283878 scopus 로고    scopus 로고
    • Linking DNA damage and neurodegeneration
    • Rolig RL, McKinnon PJ. Linking DNA damage and neurodegeneration. Trends Neuroscie 2000; 23:417-24.
    • (2000) Trends Neuroscie , vol.23 , pp. 417-424
    • Rolig, R.L.1    McKinnon, P.J.2
  • 39
    • 0034335375 scopus 로고    scopus 로고
    • Brain atrophy and neuronal loss in alcoholism: A role for DNA damage?
    • Brooks PJ. Brain atrophy and neuronal loss in alcoholism: A role for DNA damage? Neurochem Int 2000; 37:403-12.
    • (2000) Neurochem Int , vol.37 , pp. 403-412
    • Brooks, P.J.1
  • 40
    • 0031975026 scopus 로고    scopus 로고
    • Response of postmitotic neurons to X-irradiation: Implications for the role of DNA damage in neuronal apoptosis
    • Gobbel GT, Bellinzona M, Vogt AR, Gupta N, Fike JR, Chan PH. Response of postmitotic neurons to X-irradiation:Implications for the role of DNA damage in neuronal apoptosis. J Neurosci 1998; 18:147-55.
    • (1998) J Neurosci , vol.18 , pp. 147-155
    • Gobbel, G.T.1    Bellinzona, M.2    Vogt, A.R.3    Gupta, N.4    Fike, J.R.5    Chan, P.H.6
  • 41
    • 0029738086 scopus 로고    scopus 로고
    • Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I: Evidence for cell cycle-independent toxicity
    • Morris EJ, Geller HM. Induction of neuronal apoptosis by camptothecin, an inhibitor of DNA topoisomerase-I:Evidence for cell cycle-independent toxicity. J Cell Biol 1996; 134, 757-70.
    • (1996) J Cell Biol , vol.134 , pp. 757-770
    • Morris, E.J.1    Geller, H.M.2
  • 42
    • 0030633568 scopus 로고    scopus 로고
    • RecA protein: Structure, function, and role in recombinational DNA repair
    • Roca AI, Cox MM. RecA protein:Structure, function, and role in recombinational DNA repair. Prog Nucleic Acid Res Mol Biol 1997; 56:129-223.
    • (1997) Prog Nucleic Acid Res Mol Biol , vol.56 , pp. 129-223
    • Roca, A.I.1    Cox, M.M.2
  • 43
    • 0033961277 scopus 로고    scopus 로고
    • Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression
    • Nouspikel T, Hanawalt PC. Terminally differentiated human neurons repair transcribed genes but display attenuated global DNA repair and modulation of repair gene expression. Mol Cell Biol 2000; 20:1562-70.
    • (2000) Mol Cell Biol , vol.20 , pp. 1562-1570
    • Nouspikel, T.1    Hanawalt, P.C.2
  • 44
    • 0025827017 scopus 로고
    • Gene-specific DNA repair in terminally differentiating rat myoblasts
    • Ho L, Hanawalt PC. Gene-specific DNA repair in terminally differentiating rat myoblasts. Mutat Res 1991; 255:123-41.
    • (1991) Mutat Res , vol.255 , pp. 123-141
    • Ho, L.1    Hanawalt, P.C.2
  • 45
    • 0021905437 scopus 로고
    • DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall
    • Bohr VA, Smith CA, Okumoto DS, Hanawalt PC. DNA repair in an active gene:Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall. Cell 1985; 40:359-69.
    • (1985) Cell , vol.40 , pp. 359-369
    • Bohr, V.A.1    Smith, C.A.2    Okumoto, D.S.3    Hanawalt, P.C.4
  • 46
    • 0023663101 scopus 로고
    • Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene
    • Mellon I, Spivak G, Hanawalt PC. Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene. Cell 1987; 51:241-9.
    • (1987) Cell , vol.51 , pp. 241-249
    • Mellon, I.1    Spivak, G.2    Hanawalt, P.C.3
  • 47
    • 0036712428 scopus 로고    scopus 로고
    • When machines get stuck-obstructed RNA polymerase II: Displacement, degradation or suicide
    • van den Boom V, Jaspers NG, Vermeulen W. When machines get stuck-obstructed RNA polymerase II:Displacement, degradation or suicide. Bioessays. 2002; 24:780-4.
    • (2002) Bioessays , vol.24 , pp. 780-784
    • Van Den Boom, V.1    Jaspers, N.G.2    Vermeulen, W.3
  • 48
    • 0036012794 scopus 로고    scopus 로고
    • DNA repair in terminally differentiated cells
    • Nouspikel T, Hanawalt PC. DNA repair in terminally differentiated cells. DNA Repair (Amst) 2002; 1:59-75.
    • (2002) DNA Repair (Amst) , vol.1 , pp. 59-75
    • Nouspikel, T.1    Hanawalt, P.C.2
  • 49
    • 0033590624 scopus 로고    scopus 로고
    • Inhibition of RNA polymerase II as a trigger for the p53 response
    • Ljungman M, Zhang F, Chen F, Rainbow AJ, McKay BC. Inhibition of RNA polymerase II as a trigger for the p53 response. Oncogene 1999; 18:583-92.
    • (1999) Oncogene , vol.18 , pp. 583-592
    • Ljungman, M.1    Zhang, F.2    Chen, F.3    Rainbow, A.J.4    McKay, B.C.5
  • 50
    • 0034329742 scopus 로고    scopus 로고
    • Apoptosis in neurodegenerative disorders
    • Mattson MP. Apoptosis in neurodegenerative disorders. Nat Rev Mol Cell Biol 2000; 1:120-9.
    • (2000) Nat Rev Mol Cell Biol , vol.1 , pp. 120-129
    • Mattson, M.P.1
  • 51
    • 0037417220 scopus 로고    scopus 로고
    • Apoptosis and caspases in neurodegenerative diseases
    • Friedlander RM. Apoptosis and caspases in neurodegenerative diseases. N Engl J Med 2003; 348:1365-75.
    • (2003) N Engl J Med , vol.348 , pp. 1365-1375
    • Friedlander, R.M.1
  • 52
    • 0037366104 scopus 로고    scopus 로고
    • Oxidative stress, cell cycle, and neurodegeneration
    • Klein JA, Ackerman SL. Oxidative stress, cell cycle, and neurodegeneration. J Clin Invest 2003; 111:785-93.
    • (2003) J Clin Invest , vol.111 , pp. 785-793
    • Klein, J.A.1    Ackerman, S.L.2
  • 53
    • 0035003439 scopus 로고    scopus 로고
    • Chemistry and biochemistry of oxidative stress in neurodegenerative disease
    • Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem 2001; 8:721-38.
    • (2001) Curr Med Chem , vol.8 , pp. 721-738
    • Sayre, L.M.1    Smith, M.A.2    Perry, G.3
  • 54
    • 0028180518 scopus 로고
    • A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
    • Hensley K, Carney JM, Mattson MP, Aksenova M, Harris M, Wu JF, et al. A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease. Proc Natl Acad Sci USA 1994; 91:3270-4.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3270-3274
    • Hensley, K.1    Carney, J.M.2    Mattson, M.P.3    Aksenova, M.4    Harris, M.5    Wu, J.F.6
  • 55
    • 0035370304 scopus 로고    scopus 로고
    • New insights into progressive supranuclear palsy
    • Albers DS, Augood SJ. New insights into progressive supranuclear palsy. Trends Neurosci 2001; 24:347-53.
    • (2001) Trends Neurosci , vol.24 , pp. 347-353
    • Albers, D.S.1    Augood, S.J.2
  • 56
    • 0029751104 scopus 로고    scopus 로고
    • Oxidative stress and the pathogenesis of Parkinson's disease
    • Jenner P, Olanow CW. Oxidative stress and the pathogenesis of Parkinson's disease. Neurology 1996; 47:S161-70.
    • (1996) Neurology , vol.47
    • Jenner, P.1    Olanow, C.W.2
  • 58
    • 0031754202 scopus 로고    scopus 로고
    • Increased nuclear DNA oxidation in the brain in Alzheimer's disease
    • Gabbita SP, Lovell MA, Markesbery WR. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. J Neurochem 1998; 71:2034-40.
    • (1998) J Neurochem , vol.71 , pp. 2034-2040
    • Gabbita, S.P.1    Lovell, M.A.2    Markesbery, W.R.3
  • 59
    • 0036733355 scopus 로고    scopus 로고
    • The therapeutic potential of poly(ADP-ribose) polymerase inhibitors
    • Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev 2002; 54:375-429.
    • (2002) Pharmacol Rev , vol.54 , pp. 375-429
    • Virag, L.1    Szabo, C.2
  • 60
    • 0025973703 scopus 로고
    • Chemical determination of free radical-induced damage to DNA
    • Dizdaroglu M. Chemical determination of free radical-induced damage to DNA. Free Radic Biol Med 1991; 10:225-42.
    • (1991) Free Radic Biol Med , vol.10 , pp. 225-242
    • Dizdaroglu, M.1
  • 62
    • 0030806869 scopus 로고    scopus 로고
    • DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology
    • Lucassen PJ, Chung WC, Kamphorst W, Swaab DF. DNA damage distribution in the human brain as shown by in situ end labeling; area-specific differences in aging and Alzheimer disease in the absence of apoptotic morphology. J Neuropathol Exp Neurol. 1997; 56:887-900.
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 887-900
    • Lucassen, P.J.1    Chung, W.C.2    Kamphorst, W.3    Swaab, D.F.4
  • 63
    • 0032734510 scopus 로고    scopus 로고
    • DNA strand breaks in Alzheimer's disease
    • Adamec E, Vonsattel JP, Nixon RA. DNA strand breaks in Alzheimer's disease. Brain Res 1999; 849:67-77.
    • (1999) Brain Res , vol.849 , pp. 67-77
    • Adamec, E.1    Vonsattel, J.P.2    Nixon, R.A.3
  • 65
    • 0036942993 scopus 로고    scopus 로고
    • Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain
    • Iida T, Furuta A, Nishioka K, Nakabeppu Y, Iwaki T. Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain. Acta Neuropathol (Berl) 2002; 103:20-5.
    • (2002) Acta Neuropathol (Berl) , vol.103 , pp. 20-25
    • Iida, T.1    Furuta, A.2    Nishioka, K.3    Nakabeppu, Y.4    Iwaki, T.5
  • 66
    • 0032462852 scopus 로고    scopus 로고
    • Can oxidative DNA damage be used as a biomarker of cancer risk in humans. Problems, resolutions and preliminary results from nutritional supplementation studies
    • Halliwell B. Can oxidative DNA damage be used as a biomarker of cancer risk in humans. Problems, resolutions and preliminary results from nutritional supplementation studies. Free Radic Res 1998; 29:469-86.
    • (1998) Free Radic Res , vol.29 , pp. 469-486
    • Halliwell, B.1
  • 67
    • 0036469268 scopus 로고    scopus 로고
    • N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons
    • Wartiovaara K, Barnabe-Heider F, Miller FD, Kaplan DR. N-myc promotes survival and induces S-phase entry of postmitotic sympathetic neurons. J Neurosci 2002; 22:815-24.
    • (2002) J Neurosci , vol.22 , pp. 815-824
    • Wartiovaara, K.1    Barnabe-Heider, F.2    Miller, F.D.3    Kaplan, D.R.4
  • 68
    • 0033635551 scopus 로고    scopus 로고
    • Mitotic activation: A convergent mechanism for a cohort of neurodegenerative diseases
    • Husseman JW, Nochlin D, Vincent I. Mitotic activation:A convergent mechanism for a cohort of neurodegenerative diseases. Neurobiol Aging 2000; 21:815-28.
    • (2000) Neurobiol Aging , vol.21 , pp. 815-828
    • Husseman, J.W.1    Nochlin, D.2    Vincent, I.3
  • 69
    • 0027178335 scopus 로고
    • Cell death and the cell cycle: A relationship between transformation and neurodegeneration?
    • Heintz N. Cell death and the cell cycle:A relationship between transformation and neurodegeneration? Trends Biochem Sci 1993; 18:157-9.
    • (1993) Trends Biochem Sci , vol.18 , pp. 157-159
    • Heintz, N.1
  • 71
    • 0029078677 scopus 로고
    • The induction of multiple cell cycle events precedes target-related neuronal death
    • Herrup K, Busser JC. The induction of multiple cell cycle events precedes target-related neuronal death. Development 1995; 121:2385-95.
    • (1995) Development , vol.121 , pp. 2385-2395
    • Herrup, K.1    Busser, J.C.2
  • 73
    • 0035871660 scopus 로고    scopus 로고
    • DNA replication precedes neuronal cell death in Alzheimer's disease
    • Yang Y, Geldmacher DS, Herrup K. DNA replication precedes neuronal cell death in Alzheimer's disease. J Neurosci 2001; 21:2661-8.
    • (2001) J Neurosci , vol.21 , pp. 2661-2668
    • Yang, Y.1    Geldmacher, D.S.2    Herrup, K.3
  • 74
    • 0036282745 scopus 로고    scopus 로고
    • Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery
    • Konishi Y, Lehtinen M, Donovan N, Bonni A. Cdc2 phosphorylation of BAD links the cell cycle to the cell death machinery. Mol Cell 2002; 9:1005-16.
    • (2002) Mol Cell , vol.9 , pp. 1005-1016
    • Konishi, Y.1    Lehtinen, M.2    Donovan, N.3    Bonni, A.4
  • 76
    • 0035990906 scopus 로고    scopus 로고
    • Cyclin-dependent kinases as potential targets to improve stroke outcome
    • O'Hare M, Wang F, Park DS. Cyclin-dependent kinases as potential targets to improve stroke outcome. Pharmacol Ther 2002; 93:135-43.
    • (2002) Pharmacol Ther , vol.93 , pp. 135-143
    • O'Hare, M.1    Wang, F.2    Park, D.S.3
  • 77
    • 0037442820 scopus 로고    scopus 로고
    • Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition
    • Rideout HJ, Wang Q, Park DS, Stefanis L. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition. J Neurosci 2003; 23:1237-45.
    • (2003) J Neurosci , vol.23 , pp. 1237-1245
    • Rideout, H.J.1    Wang, Q.2    Park, D.S.3    Stefanis, L.4
  • 78
    • 0742281300 scopus 로고    scopus 로고
    • E2F1 and c-Myc in cell growth and death
    • Matsumura I, Tanaka H, Kanakura Y. E2F1 and c-Myc in cell growth and death. Cell Cycle 2003; 2:333-8.
    • (2003) Cell Cycle , vol.2 , pp. 333-338
    • Matsumura, I.1    Tanaka, H.2    Kanakura, Y.3
  • 79
    • 0037224933 scopus 로고    scopus 로고
    • Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta
    • El-Khodor BF, Oo TF, Kholodilov N, Burke RE. Ectopic expression of cell cycle markers in models of induced programmed cell death in dopamine neurons of the rat substantia nigra pars compacta. Exp Neurol 2003; 179:17-27.
    • (2003) Exp Neurol , vol.179 , pp. 17-27
    • El-Khodor, B.F.1    Oo, T.F.2    Kholodilov, N.3    Burke, R.E.4
  • 80
    • 0035879076 scopus 로고    scopus 로고
    • Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death
    • Katchanov J, Harms C, Gertz K, Hauck L, Waeber C, Hirt L, et al. Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death. J Neurosci 2001; 21:5045-53.
    • (2001) J Neurosci , vol.21 , pp. 5045-5053
    • Katchanov, J.1    Harms, C.2    Gertz, K.3    Hauck, L.4    Waeber, C.5    Hirt, L.6
  • 81
    • 0037444453 scopus 로고    scopus 로고
    • Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1
    • Nguyen MD, Boudreau M, Kriz J, Couillard-Despres S, Kaplan DR, Julien JP. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. J Neurosci 2003; 23:2131-40.
    • (2003) J Neurosci , vol.23 , pp. 2131-2140
    • Nguyen, M.D.1    Boudreau, M.2    Kriz, J.3    Couillard-Despres, S.4    Kaplan, D.R.5    Julien, J.P.6
  • 82
    • 0032585817 scopus 로고    scopus 로고
    • Mechanisms of neuronal death in Down's syndrome
    • Nagy Z. Mechanisms of neuronal death in Down's syndrome. J Neural Transm Suppl 1999; 57:233-45.
    • (1999) J Neural Transm Suppl , vol.57 , pp. 233-245
    • Nagy, Z.1
  • 84
    • 0036968946 scopus 로고    scopus 로고
    • Niemann-Pick disease type C yields possible due for why cerebellar neurons do not form neurofibrillary tangles
    • Bu B, Klunemann H, Suzuki K, Li J, Bird T, Jin LW, et al. Niemann-Pick disease type C yields possible due for why cerebellar neurons do not form neurofibrillary tangles. Neurobiol Dis 2002; 11:285-97.
    • (2002) Neurobiol Dis , vol.11 , pp. 285-297
    • Bu, B.1    Klunemann, H.2    Suzuki, K.3    Li, J.4    Bird, T.5    Jin, L.W.6
  • 85
    • 1542381057 scopus 로고    scopus 로고
    • Cell cycle regulation of neuronal apoptosis in development and disease
    • Becker EB, Bonni A. Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 2004; 72:1-25.
    • (2004) Prog Neurobiol , vol.72 , pp. 1-25
    • Becker, E.B.1    Bonni, A.2
  • 86
    • 0030996226 scopus 로고    scopus 로고
    • A sequence in the N- Terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein a
    • Nagelhus TA, Haug T, Singh KK, Keshav KF, Skorpen F, Occerlei M, et al. A sequence in the N- terminal region of human uracil-DNA glycosylase with homology to XPA interacts with the C-terminal part of the 34-kDa subunit of replication protein A. J Biol Chem 1997; 272:6561-6.
    • (1997) J Biol Chem , vol.272 , pp. 6561-6566
    • Nagelhus, T.A.1    Haug, T.2    Singh, K.K.3    Keshav, K.F.4    Skorpen, F.5    Occerlei, M.6
  • 87
    • 0028986617 scopus 로고
    • E2F-1 and a cyclin-like DNA repair enzyme, uracil-DNA glycosylase, provide evidence for an autoregulatory mechanism for transcription
    • Walsh MJ, Shue G, Spidoni K, Kapoor A. E2F-1 and a cyclin-like DNA repair enzyme, uracil-DNA glycosylase, provide evidence for an autoregulatory mechanism for transcription. J. Biol. Chem 1995; 270:5289-98.
    • (1995) J Biol Chem , vol.270 , pp. 5289-5298
    • Walsh, M.J.1    Shue, G.2    Spidoni, K.3    Kapoor, A.4
  • 89
    • 0034655373 scopus 로고    scopus 로고
    • Apoptosis or senescence-like growth arrest: Influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts
    • Chen QM, Liu J, Merrett JB. Apoptosis or senescence-like growth arrest:Influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts. Biochem J 2000; 347:543-51.
    • (2000) Biochem J , vol.347 , pp. 543-551
    • Chen, Q.M.1    Liu, J.2    Merrett, J.B.3
  • 90
    • 85078513502 scopus 로고    scopus 로고
    • DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis
    • Huang X, Traganos F, Darzynkiewicz Z. DNA damage induced by DNA topoisomerase I- and topoisomerase II-inhibitors detected by histone H2AX phosphorylation in relation to the cell cycle phase and apoptosis. Cell Cycle 2003; 2:614-9.
    • (2003) Cell Cycle , vol.2 , pp. 614-619
    • Huang, X.1    Traganos, F.2    Darzynkiewicz, Z.3
  • 91
    • 0036900066 scopus 로고    scopus 로고
    • Genetic and environmental factors in cancer and neurodegenerative diseases
    • Migliore L, Coppede F. Genetic and environmental factors in cancer and neurodegenerative diseases. Mutat Res 2002; 512:135-53.
    • (2002) Mutat Res , vol.512 , pp. 135-153
    • Migliore, L.1    Coppede, F.2
  • 92
    • 0031663617 scopus 로고    scopus 로고
    • ATM: From gene to function
    • Rotman G, Shiloh Y. ATM:From gene to function. Hum Mol Genet 1998; 7:1555-63.
    • (1998) Hum Mol Genet , vol.7 , pp. 1555-1563
    • Rotman, G.1    Shiloh, Y.2
  • 93
    • 0033516991 scopus 로고    scopus 로고
    • Targeting in double-strand breaks to replicating DNA identifies a subpathway of DSB repair that is defective ataxia-telangiectasia cells
    • Johnson RT, Gotoh E, Mullinger AM, Ryan AJ, Shiloh Y, Ziv Y, et al. Targeting in double-strand breaks to replicating DNA identifies a subpathway of DSB repair that is defective ataxia-telangiectasia cells. Biochem Biophys Res Commun 1999; 261:317-25.
    • (1999) Biochem Biophys Res Commun , vol.261 , pp. 317-325
    • Johnson, R.T.1    Gotoh, E.2    Mullinger, A.M.3    Ryan, A.J.4    Shiloh, Y.5    Ziv, Y.6
  • 94
    • 0032524070 scopus 로고    scopus 로고
    • Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system
    • Herzog KH, Chong MJ, Kapsetaki M, Morgan JI, McKinnon PJ. Requirement for Atm in ionizing radiation-induced cell death in the developing central nervous system. Science 1998; 280:1089-91.
    • (1998) Science , vol.280 , pp. 1089-1091
    • Herzog, K.H.1    Chong, M.J.2    Kapsetaki, M.3    Morgan, J.I.4    McKinnon, P.J.5
  • 96
    • 0037428712 scopus 로고    scopus 로고
    • Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein
    • Macleod MR, Ramage L, McGregor A, Seekl JR. Reduced NMDA-induced apoptosis in neurons lacking ataxia telangiectasia mutated protein. Neuroreport 2003; 14:215-7.
    • (2003) Neuroreport , vol.14 , pp. 215-217
    • Macleod, M.R.1    Ramage, L.2    McGregor, A.3    Seekl, J.R.4


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