메뉴 건너뛰기




Volumn 2, Issue 12, 2000, Pages 893-898

Participation of ATM in insulin signalling through phosphorylation of elF-4E-binding protein 1

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; GENE PRODUCT; INITIATION FACTOR; INSULIN; PHOSPHOTRANSFERASE;

EID: 0033662156     PISSN: 14657392     EISSN: None     Source Type: Journal    
DOI: 10.1038/35046542     Document Type: Article
Times cited : (244)

References (50)
  • 4
    • 15844426692 scopus 로고    scopus 로고
    • Atm deficient mice: A paradigm of ataxia telangiectasia
    • (1996) Cell , vol.86 , pp. 159-171
    • Barlow, C.1
  • 5
    • 0018192112 scopus 로고
    • Extreme insulin resistance in ataxia telangiectasia: Defect in affinity of insulin receptors
    • (1978) N. Engl. J. Med. , vol.298 , pp. 1164-1171
    • Bar, R.S.1
  • 9
    • 0026496885 scopus 로고
    • A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
    • (1992) Cell , vol.71 , pp. 587-597
    • Kastan, M.B.1
  • 10
    • 0029821651 scopus 로고    scopus 로고
    • Dual roles of ATM in the cellular response to radiation and in cell growth control
    • (1996) Genes Dev. , vol.10 , pp. 2401-2410
    • Xu, Y.1    Baltimore, D.2
  • 11
    • 0021041684 scopus 로고
    • Abnormal response of ataxia-telangiectasia cells to agents that break the deoxyribose moiety of DNA via a targeted free radical mechanism
    • (1983) Carcinogenesis , vol.4 , pp. 1317-1322
    • Shiloh, Y.1    Tabor, E.2    Becker, Y.3
  • 15
    • 0029057336 scopus 로고
    • A single ataxia telangiectasia gene with a product similar to PI-3 kinase
    • (1995) Science , vol.268 , pp. 1749-1753
    • Savitsky, K.1
  • 16
    • 0032508608 scopus 로고    scopus 로고
    • Activation of the ATM kinase by ionizing radiation and phosphorylation of p53
    • (1998) Science , vol.281 , pp. 1677-1679
    • Canman, C.E.1
  • 17
    • 0032508504 scopus 로고    scopus 로고
    • Enhanced phosphorylation of p53 by ATM in response to DNA damage
    • (1998) Science , vol.281 , pp. 1674-1677
    • Banin, S.1
  • 19
    • 0034616329 scopus 로고    scopus 로고
    • 2/M DNA damage checkpoint by inhibiting ataxia-telangiectasia-mutated kinase activity
    • (2000) J. Biol. Chem. , vol.275 , pp. 10342-10348
    • Zhou, B.B.1
  • 20
    • 0034611728 scopus 로고    scopus 로고
    • ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
    • (2000) Nature , vol.404 , pp. 613-617
    • Lim, D.S.1
  • 21
    • 0032189483 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
    • (1998) Cancer Res. , vol.58 , pp. 4375-4382
    • Sarkaria, J.N.1
  • 22
    • 0034677786 scopus 로고    scopus 로고
    • Purification and characterization of ATM from human placenta. A manganese-dependent, wortmannin-sensitive serine/threonine protein kinase
    • (2000) J. Biol. Chem. , vol.275 , pp. 7803-7810
    • Chan, D.W.1
  • 23
    • 0033153166 scopus 로고    scopus 로고
    • Regulation of 4E-BP1 phosphorylation: A novel two-step mechanism
    • (1999) Genes Dev. , vol.13 , pp. 1422-1437
    • Gingras, A.C.1
  • 26
    • 0030716488 scopus 로고    scopus 로고
    • Regulation of elF-4E BP1 phosphorylation by mTOR
    • (1997) J. Biol. Chem. , vol.272 , pp. 26457-26463
    • Hara, K.1
  • 27
    • 0030881836 scopus 로고    scopus 로고
    • Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin
    • (1997) Science , vol.277 , pp. 99-101
    • Brunn, G.J.1
  • 28
    • 0028126506 scopus 로고
    • PHAS-1 as a link between mitogen-activated protein kinase and translation initiation
    • (1994) Science , vol.266 , pp. 653-656
    • Lin, T.A.1
  • 29
    • 0028034233 scopus 로고
    • Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function
    • (1994) Nature , vol.371 , pp. 762-767
    • Pause, A.1
  • 35
    • 0029103330 scopus 로고
    • Control of p70 s6 kinase by kinase activity of FRAP in vivo
    • (1995) Nature , vol.377 , pp. 441-446
    • Brown, E.J.1
  • 36
    • 0030013407 scopus 로고    scopus 로고
    • Both rapamycin-sensitive and -insensitive pathways are involved in the phosphorylation of the initiation factor-4E-binding protein (4E-BP1) in response to insulin in rat epididymal fat-cells
    • (1996) Biochem. J. , vol.316 , pp. 447-453
    • Diggle, T.A.1
  • 41
    • 0030941281 scopus 로고    scopus 로고
    • Genetic interactions between atm and p53 influence cellular proliferation and irradiation-induced cell cycle checkpoints
    • (1997) Cancer Res. , vol.57 , pp. 1664-1667
    • Westphal, C.H.1
  • 42
    • 0031047915 scopus 로고    scopus 로고
    • The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1840-1845
    • Brown, K.D.1
  • 43
    • 0030472725 scopus 로고    scopus 로고
    • Analysis of the ATM protein in wild-type and ataxia telangiectasia cells
    • (1996) Oncogene , vol.13 , pp. 2707-2716
    • Lakin, N.D.1
  • 45
    • 0033607810 scopus 로고    scopus 로고
    • Localization of a portion of extranuclear ATM to peroxisomes
    • (1999) J. Biol. Chem. , vol.274 , pp. 34277-34282
    • Watters, D.1
  • 47
    • 18244421978 scopus 로고    scopus 로고
    • ATM deficiency results in severe meiotic disruption as early as leptonema of prophase I
    • (1998) Development , vol.125 , pp. 4007-4017
    • Barlow, C.1
  • 48
    • 0032555458 scopus 로고    scopus 로고
    • Expression of the ataxia-telangiectasia gene (ATM) product in human cerebellar neurons during development
    • (1998) Neurosci. Lett. , vol.252 , pp. 195-198
    • Oka, A.1    Takashima, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.