Senescent cells: A novel therapeutic target for aging and age-related diseases

Clinical Pharmacology and Therapeutics

Volumn 93, Issue 1, 2013, Pages 105-116

  Naylor, R M ^a   Baker, D J ^a   Van Deursen, J M ^a,b  

^a MAYO GRADUATE SCHOOL   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; CYCLIN DEPENDENT KINASE INHIBITOR 2A; INTERLEUKIN 6; INTERLEUKIN 8; PROTEIN P53; REACTIVE OXYGEN METABOLITE;

ACUTE CORONARY SYNDROME; ADIPOSE TISSUE; ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; ATHEROSCLEROSIS; BIOACCUMULATION; CANCER CHEMOTHERAPY; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CATARACT; CD8+ T LYMPHOCYTE; CELL AGING; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL THERAPY; CHROMOSOME SEGREGATION; CHRONIC DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; DISEASE ASSOCIATION; DNA DAMAGE; EXTRACELLULAR MATRIX; FIBROBLAST; FIBROSING ALVEOLITIS; GENOTOXICITY; GLAUCOMA; HEALTH CARE COST; HYPERTENSION; IMMUNOCOMPETENT CELL; INHIBITION KINETICS; METASTASIS; MICROENVIRONMENT; MUSCLE ATROPHY; NEUROFIBRILLARY TANGLE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OSTEOARTHRITIS; OXIDATIVE STRESS; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUALITY OF LIFE; RETINA MACULA DEGENERATION; SENESCENCE; SIGNAL TRANSDUCTION; SKIN CANCER; SUBSTANTIA NIGRA PARS COMPACTA; TARGET CELL; TARGET CELL DESTRUCTION; TRANSCRIPTION INITIATION; WOUND HEALING;

AGING; ANIMALS; CARDIOVASCULAR DISEASES; CELL AGING; CHRONIC DISEASE; DIABETES MELLITUS; GENE TARGETING; HUMANS; NEOPLASMS;

EID: 84871302192     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.193     Document Type: Article

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