-
1
-
-
79955535643
-
Macrophages in the pathogenesis of atherosclerosis
-
Moore, K.J. & Tabas, I. Macrophages in the pathogenesis of atherosclerosis. Cell 145, 341-355 (2011).
-
(2011)
Cell
, vol.145
, pp. 341-355
-
-
Moore, K.J.1
Tabas, I.2
-
2
-
-
44649153859
-
Contribution of macromolecular structure to the retention of low-density lipoprotein at arterial branch points
-
DOI 10.1161/CIRCULATIONAHA.107.754614
-
Kwon, G.P., Schroeder, J.L., Amar, M.J., Remaley, A.T. & Balaban, R.S. Contribution of macromolecular structure to the retention of low-density lipoprotein at arterial branch points. Circulation 117, 2919-2927 (2008). (Pubitemid 351787076)
-
(2008)
Circulation
, vol.117
, Issue.22
, pp. 2919-2927
-
-
Kwon, G.P.1
Schroeder, J.L.2
Amar, M.J.3
Remaley, A.T.4
Balaban, R.S.5
-
3
-
-
79951669207
-
The immune system in atherosclerosis
-
Hansson, G.K. & Hermansson, A. The immune system in atherosclerosis. Nat. Immunol. 12, 204-212 (2011).
-
(2011)
Nat. Immunol.
, vol.12
, pp. 204-212
-
-
Hansson, G.K.1
Hermansson, A.2
-
4
-
-
79960048075
-
Stabilisation of atherosclerotic plaques. Position Paper of the European Society of Cardiology (ESC) Working Group of Atherosclerosis and Vascular Biology
-
Ylä-Herttuala, S. et al. Stabilisation of atherosclerotic plaques. Position Paper of the European Society of Cardiology (ESC) Working Group of Atherosclerosis and Vascular Biology. Thromb. Haemost. 106, 1-19 (2011).
-
(2011)
Thromb. Haemost.
, vol.106
, pp. 1-19
-
-
Ylä-Herttuala, S.1
-
5
-
-
52949118482
-
The multifaceted contributions of leukocyte subsets to atherosclerosis: Lessons from mouse models
-
Weber, C., Zernecke, A. & Libby, P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat. Rev. Immunol. 8, 802-815 (2008).
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 802-815
-
-
Weber, C.1
Zernecke, A.2
Libby, P.3
-
6
-
-
76449107634
-
Monocytes in atherosclerosis: Subsets and functions
-
Woollard, K.J. & Geissmann, F. Monocytes in atherosclerosis: subsets and functions. Nat. Rev. Cardiol. 7, 77-86 (2010).
-
(2010)
Nat. Rev. Cardiol.
, vol.7
, pp. 77-86
-
-
Woollard, K.J.1
Geissmann, F.2
-
7
-
-
75949126309
-
Therapeutic targeting of chemokine interactions in atherosclerosis
-
Koenen, R.R. & Weber, C. Therapeutic targeting of chemokine interactions in atherosclerosis. Nat. Rev. Drug Discov. 9, 141-153 (2010).
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 141-153
-
-
Koenen, R.R.1
Weber, C.2
-
8
-
-
33845970192
-
hi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata
-
DOI 10.1172/JCI29950
-
Swirski, F.K. et al. Ly-6Chi monocytes dominate hypercholesterolemia- associated monocytosis and give rise to macrophages in atheromata. J. Clin. Invest. 117, 195-205 (2007). (Pubitemid 46048466)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 195-205
-
-
Swirski, F.K.1
Libby, P.2
Aikawa, E.3
Alcaide, P.4
Luscinskas, F.W.5
Weissleder, R.6
Pittet, M.J.7
-
9
-
-
33845989083
-
Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques
-
DOI 10.1172/JCI28549
-
Tacke, F. et al. Monocyte subsets differentially employ CCR2, CCR5 and CX3CR1 to accumulate within atherosclerotic plaques. J. Clin. Invest. 117, 185-194 (2007). (Pubitemid 46048465)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 185-194
-
-
Tacke, F.1
Alvarez, D.2
Kaplan, T.J.3
Jakubzick, C.4
Spanbroek, R.5
Llodra, J.6
Garin, A.7
Liu, J.8
MacK, M.9
Van Rooijen, N.10
Lira, S.A.11
Habenicht, A.J.12
Randolph, G.J.13
-
10
-
-
41649100060
-
Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6Chi and Ly6Clo monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice
-
DOI 10.1161/CIRCULATIONAHA.107.745091
-
Combadière, C. et al. Combined inhibition of CCL2, CX3CR1, and CCR5 abrogates Ly6Chi and Ly6Clo monocytosis and almost abolishes atherosclerosis in hypercholesterolemic mice. Circulation 117, 1649-1657 (2008). (Pubitemid 351482605)
-
(2008)
Circulation
, vol.117
, Issue.13
, pp. 1649-1657
-
-
Combadiere, C.1
Potteaux, S.2
Rodero, M.3
Simon, T.4
Pezard, A.5
Esposito, B.6
Merval, R.7
Proudfoot, A.8
Tedgui, A.9
Mallat, Z.10
-
11
-
-
41649107036
-
Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: Evidence for independent chemokine functions in atherogenesis
-
DOI 10.1161/CIRCULATIONAHA.107.743872
-
Saederup, N., Chan, L., Lira, S.A. & Charo, I.F. Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in Ccr2-/-mice: evidence for independent chemokine functions in atherogenesis. Circulation 117, 1642-1648 (2008). (Pubitemid 351482604)
-
(2008)
Circulation
, vol.117
, Issue.13
, pp. 1642-1648
-
-
Saederup, N.1
Chan, L.2
Lira, S.A.3
Charo, I.F.4
-
12
-
-
77951694064
-
Chemokines in the vascular inflammatory response of atherosclerosis
-
Zernecke, A. & Weber, C. Chemokines in the vascular inflammatory response of atherosclerosis. Cardiovasc. Res. 86, 192-201 (2010).
-
(2010)
Cardiovasc. Res.
, vol.86
, pp. 192-201
-
-
Zernecke, A.1
Weber, C.2
-
13
-
-
23844437323
-
Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo
-
DOI 10.1161/CIRCULATIONAHA.104.520718
-
Veillard, N.R. et al. Differential influence of chemokine receptors CCR2 and CXCR3 in development of atherosclerosis in vivo. Circulation 112, 870-878 (2005). (Pubitemid 41170074)
-
(2005)
Circulation
, vol.112
, Issue.6
, pp. 870-878
-
-
Veillard, N.R.1
Steffens, S.2
Pelli, G.3
Lu, B.4
Kwak, B.R.5
Gerard, C.6
Charo, I.F.7
MacH, F.8
-
14
-
-
33744981802
-
Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells
-
DOI 10.1161/CIRCULATIONAHA.105.605121, PII 0000301720060516000010
-
Heller, E.A. et al. Chemokine CXCL10 promotes atherogenesis by modulating the local balance of effector and regulatory T cells. Circulation 113, 2301-2312 (2006). (Pubitemid 43947976)
-
(2006)
Circulation
, vol.113
, Issue.19
, pp. 2301-2312
-
-
Heller, E.A.1
Liu, E.2
Tager, A.M.3
Yuan, Q.4
Lin, A.Y.5
Ahluwalia, N.6
Jones, K.7
Koehn, S.L.8
Lok, V.M.9
Aikawa, E.10
Moore, K.J.11
Luster, A.D.12
Gerszten, R.E.13
-
15
-
-
38549146090
-
CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice
-
van Wanrooij, E.J. et al. CXCR3 antagonist NBI-74330 attenuates atherosclerotic plaque formation in LDL receptor-deficient mice. Arterioscler. Thromb. Vasc. Biol. 28, 251-257 (2008).
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 251-257
-
-
Van Wanrooij, E.J.1
-
16
-
-
33746855163
-
Role of bone marrow-derived CC-chemokine receptor 5 in the development of atherosclerosis of low-density lipoprotein receptor knockout mice
-
DOI 10.1161/01.ATV.0000231527.22762.71, PII 0004360520060800000026
-
Potteaux, S. et al. Role of bone marrow-derived CC-chemokine receptor 5 in the development of atherosclerosis of low-density lipoprotein receptor knockout mice. Arterioscler. Thromb. Vasc. Biol. 26, 1858-1863 (2006). (Pubitemid 44305341)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.8
, pp. 1858-1863
-
-
Potteaux, S.1
Combadiere, C.2
Esposito, B.3
Lecureuil, C.4
Ait-Oufella, H.5
Merval, R.6
Ardouin, P.7
Tedgui, A.8
Mallat, Z.9
-
17
-
-
33846404914
-
Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice
-
DOI 10.1161/01.ATV.0000253886.44609.ae, PII 0004360520070200000019
-
Braunersreuther, V. et al. Ccr5 but not Ccr1 deficiency reduces development of diet-induced atherosclerosis in mice. Arterioscler. Thromb. Vasc. Biol. 27, 373-379 (2007). (Pubitemid 46143054)
-
(2007)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.27
, Issue.2
, pp. 373-379
-
-
Braunersreuther, V.1
Zernecke, A.2
Arnaud, C.3
Liehn, E.A.4
Steffens, S.5
Shagdarsuren, E.6
Bidzhekov, K.7
Burger, F.8
Pelli, G.9
Luckow, B.10
MacH, F.11
Weber, C.12
-
18
-
-
0037231665
-
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein e
-
DOI 10.1038/nm810
-
Huo, Y. et al. Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E. Nat. Med. 9, 61-67 (2003). (Pubitemid 36098261)
-
(2003)
Nature Medicine
, vol.9
, Issue.1
, pp. 61-67
-
-
Huo, Y.1
Schober, A.2
Forlow, S.B.3
Smith, D.F.4
Hyman, M.C.5
Jung, S.6
Littman, D.R.7
Weber, C.8
Ley, K.9
-
19
-
-
21544460952
-
Platelet microparticles: A transcellular delivery system for RANTES promoting monocyte recruitment on endothelium
-
DOI 10.1161/01.ATV.0000170133.43608.37
-
Mause, S.F., von Hundelshausen, P., Zernecke, A., Koenen, R.R. & Weber, C. Platelet microparticles: a transcellular delivery system for RANTES promoting monocyte recruitment on endothelium. Arterioscler. Thromb. Vasc. Biol. 25, 1512-1518 (2005). (Pubitemid 40923377)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.7
, pp. 1512-1518
-
-
Mause, S.F.1
Von Hundelshausen, P.2
Zernecke, A.3
Koenen, R.R.4
Weber, C.5
-
20
-
-
1042291188
-
Antagonism of RANTES Receptors Reduces Atherosclerotic Plaque Formation in Mice
-
DOI 10.1161/01.RES.0000109793.17591.4E
-
Veillard, N.R. et al. Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice. Circ. Res. 94, 253-261 (2004). (Pubitemid 38197459)
-
(2004)
Circulation Research
, vol.94
, Issue.2
, pp. 253-261
-
-
Veillard, N.R.1
Kwak, B.2
Pelli, G.3
Mulhaupt, F.4
James, R.W.5
Proudfoot, A.E.I.6
MacH, F.7
-
21
-
-
36048981326
-
-/- mice
-
DOI 10.1160/TH07-04-0271
-
Sachais, B.S. et al. Elimination of platelet factor 4 (PF4) from platelets reduces atherosclerosis in C57BL/6 and Apoe-/-mice. Thromb. Haemost. 98, 1108-1113 (2007). (Pubitemid 350091140)
-
(2007)
Thrombosis and Haemostasis
, vol.98
, Issue.5
, pp. 1108-1113
-
-
Sachais, B.S.1
Turrentine, T.2
McKenna, J.M.D.3
Rux, A.H.4
Rader, D.5
Kowalska, M.A.6
-
22
-
-
12844273413
-
Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium
-
von Hundelshausen, P. et al. Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium. Blood 105, 924-930 (2005).
-
(2005)
Blood
, vol.105
, pp. 924-930
-
-
Von Hundelshausen, P.1
-
23
-
-
58149336758
-
Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice
-
Koenen, R.R. et al. Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice. Nat. Med. 15, 97-103 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 97-103
-
-
Koenen, R.R.1
-
24
-
-
59649092443
-
CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival
-
Landsman, L. et al. CX3CR1 is required for monocyte homeostasis and atherogenesis by promoting cell survival. Blood 113, 963-972 (2009).
-
(2009)
Blood
, vol.113
, pp. 963-972
-
-
Landsman, L.1
-
25
-
-
79960020852
-
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice
-
Weber, C. et al. CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice. J. Clin. Invest. 121, 2898-2910 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2898-2910
-
-
Weber, C.1
-
26
-
-
33644852050
-
Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice
-
DOI 10.1073/pnas.0511043103
-
Trogan, E. et al. Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. Proc. Natl. Acad. Sci. USA 103, 3781-3786 (2006). (Pubitemid 43376632)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.10
, pp. 3781-3786
-
-
Trogan, E.1
Feig, J.E.2
Dogan, S.3
Rothblat, G.H.4
Angeli, V.5
Tacke, F.6
Randolph, G.J.7
Fisher, E.A.8
-
27
-
-
79955503060
-
Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/-mice during disease regression
-
Potteaux, S. et al. Suppressed monocyte recruitment drives macrophage removal from atherosclerotic plaques of Apoe-/-mice during disease regression. J. Clin. Invest. 121, 2025-2036 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2025-2036
-
-
Potteaux, S.1
-
28
-
-
78649867645
-
LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression
-
Feig, J.E. et al. LXR promotes the maximal egress of monocyte-derived cells from mouse aortic plaques during atherosclerosis regression. J. Clin. Invest. 120, 4415-4424 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4415-4424
-
-
Feig, J.E.1
-
29
-
-
78049490016
-
Chemokine receptor 7 knockout attenuates atherosclerotic plaque development
-
Luchtefeld, M. et al. Chemokine receptor 7 knockout attenuates atherosclerotic plaque development. Circulation 122, 1621-1628 (2010).
-
(2010)
Circulation
, vol.122
, pp. 1621-1628
-
-
Luchtefeld, M.1
-
30
-
-
34249066942
-
MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment
-
DOI 10.1038/nm1567, PII NM1567
-
Bernhagen, J. et al. MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment. Nat. Med. 13, 587-596 (2007). (Pubitemid 46828480)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 587-596
-
-
Bernhagen, J.1
Krohn, R.2
Lue, H.3
Gregory, J.L.4
Zernecke, A.5
Koenen, R.R.6
Dewor, M.7
Georgiev, I.8
Schober, A.9
Leng, L.10
Kooistra, T.11
Fingerle-Rowson, G.12
Ghezzi, P.13
Kleemann, R.14
McColl, S.R.15
Bucala, R.16
Hickey, M.J.17
Weber, C.18
-
31
-
-
77952865796
-
Phagocyte partnership during the onset and resolution of inflammation
-
Soehnlein, O. & Lindbom, L. Phagocyte partnership during the onset and resolution of inflammation. Nat. Rev. Immunol. 10, 427-439 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 427-439
-
-
Soehnlein, O.1
Lindbom, L.2
-
32
-
-
66349115622
-
Emerging role of Toll-like receptors in atherosclerosis
-
Curtiss, L.K. & Tobias, P.S. Emerging role of Toll-like receptors in atherosclerosis. J. Lipid Res. 50 (suppl.), S340-S345 (2009).
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Curtiss, L.K.1
Tobias, P.S.2
-
33
-
-
77958532945
-
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress
-
Seimon, T.A. et al. Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stress. Cell Metab. 12, 467-482 (2010).
-
(2010)
Cell Metab.
, vol.12
, pp. 467-482
-
-
Seimon, T.A.1
-
34
-
-
79551472972
-
High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein E-deficient mice
-
Kanellakis, P. et al. High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol. 31, 313-319 (2011).
-
(2011)
Arterioscler. Thromb. Vasc. Biol.
, vol.31
, pp. 313-319
-
-
Kanellakis, P.1
-
35
-
-
41149085145
-
Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis
-
DOI 10.1161/CIRCRESAHA.107.160697
-
Zernecke, A. et al. Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis. Circ. Res. 102, 209-217 (2008). (Pubitemid 351651125)
-
(2008)
Circulation Research
, vol.102
, Issue.2
, pp. 209-217
-
-
Zernecke, A.1
Bot, I.2
Djalali-Talab, Y.3
Shagdarsuren, E.4
Bidzhekov, K.5
Meiler, S.6
Krohn, R.7
Schober, A.8
Sperandio, M.9
Soehnlein, O.10
Bornemann, J.11
Tacke, F.12
Biessen, E.A.13
Weber, C.14
-
36
-
-
77954583040
-
Distinct infiltration of neutrophils in lesion shoulders in Apoe-/-mice
-
Rotzius, P. et al. Distinct infiltration of neutrophils in lesion shoulders in Apoe-/-mice. Am. J. Pathol. 177, 493-500 (2010).
-
(2010)
Am. J. Pathol.
, vol.177
, pp. 493-500
-
-
Rotzius, P.1
-
37
-
-
78349304885
-
Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis
-
Drechsler, M., Megens, R.T., van Zandvoort, M., Weber, C. & Soehnlein, O. Hyperlipidemia-triggered neutrophilia promotes early atherosclerosis. Circulation 122, 1837-1845 (2010).
-
(2010)
Circulation
, vol.122
, pp. 1837-1845
-
-
Drechsler, M.1
Megens, R.T.2
Van Zandvoort, M.3
Weber, C.4
Soehnlein, O.5
-
38
-
-
56549109283
-
Increased inflammatory gene expression in ABC transporter-deficient macrophages: Free cholesterol accumulation, increased signaling via Toll-like receptors and neutrophil infiltration of atherosclerotic lesions
-
Yvan-Charvet, L. et al. Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via Toll-like receptors and neutrophil infiltration of atherosclerotic lesions. Circulation 118, 1837-1847 (2008).
-
(2008)
Circulation
, vol.118
, pp. 1837-1847
-
-
Yvan-Charvet, L.1
-
39
-
-
51649104412
-
Neutrophil secretion products pave the way for inflammatory monocytes
-
Soehnlein, O. et al. Neutrophil secretion products pave the way for inflammatory monocytes. Blood 112, 1461-1471 (2008).
-
(2008)
Blood
, vol.112
, pp. 1461-1471
-
-
Soehnlein, O.1
-
40
-
-
79952302535
-
Unexpected protective role for Toll-like receptor 3 in the arterial wall
-
Cole, J.E. et al. Unexpected protective role for Toll-like receptor 3 in the arterial wall. Proc. Natl. Acad. Sci. USA 108, 2372-2377 (2011).
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 2372-2377
-
-
Cole, J.E.1
-
41
-
-
72949116358
-
Macrophage death and defective inflammation resolution in atherosclerosis
-
Tabas, I. Macrophage death and defective inflammation resolution in atherosclerosis. Nat. Rev. Immunol. 10, 36-46 (2010).
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 36-46
-
-
Tabas, I.1
-
42
-
-
70350029796
-
NETs: A new strategy for using old weapons
-
Papayannopoulos, V. & Zychlinsky, A. NETs: a new strategy for using old weapons. Trends Immunol. 30, 513-521 (2009).
-
(2009)
Trends Immunol.
, vol.30
, pp. 513-521
-
-
Papayannopoulos, V.1
Zychlinsky, A.2
-
43
-
-
70449363613
-
Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils
-
Zhang, Z. et al. Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils. Eur. J. Immunol. 39, 3181-3194 (2009).
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 3181-3194
-
-
Zhang, Z.1
-
44
-
-
77955410626
-
Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases
-
Massberg, S. et al. Reciprocal coupling of coagulation and innate immunity via neutrophil serine proteases. Nat. Med. 16, 887-896 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 887-896
-
-
Massberg, S.1
-
45
-
-
0033749397
-
Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model
-
Ludewig, B. et al. Linking immune-mediated arterial inflammation and cholesterol-induced atherosclerosis in a transgenic mouse model. Proc. Natl. Acad. Sci. USA 97, 12752-12757 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12752-12757
-
-
Ludewig, B.1
-
46
-
-
13444250894
-
T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses
-
DOI 10.1073/pnas.0409015102
-
Buono, C. et al. T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses. Proc. Natl. Acad. Sci. USA 102, 1596-1601 (2005). (Pubitemid 40209213)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1596-1601
-
-
Buono, C.1
Binder, C.J.2
Stavrakis, G.3
Witztum, J.L.4
Glimcher, L.H.5
Lichtman, A.H.6
-
47
-
-
35148859786
-
Measles virus nucleoprotein induces a regulatory immune response and reduces atherosclerosis in mice
-
DOI 10.1161/CIRCULATIONAHA.107.699470
-
Ait-Oufella, H. et al. Measles virus nucleoprotein induces a regulatory immune response and reduces atherosclerosis in mice. Circulation 116, 1707-1713 (2007). (Pubitemid 47537845)
-
(2007)
Circulation
, vol.116
, Issue.15
, pp. 1707-1713
-
-
Ait-Oufella, H.1
Horvat, B.2
Kerdiles, Y.3
Herbin, O.4
Gourdy, P.5
Khallou-Laschet, J.6
Merval, R.7
Esposito, B.8
Tedgui, A.9
Mallat, Z.10
-
48
-
-
72449195338
-
Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice
-
Sasaki, N. et al. Oral anti-CD3 antibody treatment induces regulatory T cells and inhibits the development of atherosclerosis in mice. Circulation 120, 1996-2005 (2009).
-
(2009)
Circulation
, vol.120
, pp. 1996-2005
-
-
Sasaki, N.1
-
49
-
-
11144224296
-
Immunomodulation of atherosclerosis: Implications for vaccine development
-
DOI 10.1161/01.ATV.0000149142.42590.a2
-
Nilsson, J., Hansson, G.K. & Shah, P.K. Immunomodulation of atherosclerosis: implications for vaccine development. Arterioscler. Thromb. Vasc. Biol. 25, 18-28 (2005). (Pubitemid 40054250)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.1
, pp. 18-28
-
-
Nilsson, J.1
Hansson, G.K.2
Shah, P.K.3
-
50
-
-
77952308908
-
Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis
-
Hermansson, A. et al. Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis. J. Exp. Med. 207, 1081-1093 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1081-1093
-
-
Hermansson, A.1
-
51
-
-
4043152981
-
IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis
-
DOI 10.1172/JCI200420479
-
Binder, C.J. et al. IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J. Clin. Invest. 114, 427-437 (2004). (Pubitemid 39071615)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.3
, pp. 427-437
-
-
Binder, C.J.1
Hartvigsen, K.2
Chang, M.-K.3
Miller, M.4
Broide, D.5
Palinski, W.6
Curtiss, L.K.7
Corr, M.8
Witztum, J.L.9
-
52
-
-
33846859569
-
Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events
-
DOI 10.1194/jlr.M600361-JLR200
-
Tsimikas, S. et al. Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events. J. Lipid Res. 48, 425-433 (2007). (Pubitemid 46220609)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.2
, pp. 425-433
-
-
Tsimikas, S.1
Brilakis, E.S.2
Lennon, R.J.3
Miller, E.R.4
Witztum, J.L.5
McConnell, J.P.6
Kornman, K.S.7
Berger, P.B.8
-
53
-
-
36649010572
-
-/- Mice
-
DOI 10.1016/j.jacc.2007.07.081, PII S0735109707029762
-
Schiopu, A. et al. Recombinant antibodies to an oxidized low-density lipoprotein epitope induce rapid regression of atherosclerosis in apobec-1-/-/low-density lipoprotein receptor-/-mice. J. Am. Coll. Cardiol. 50, 2313-2318 (2007). (Pubitemid 350199611)
-
(2007)
Journal of the American College of Cardiology
, vol.50
, Issue.24
, pp. 2313-2318
-
-
Schiopu, A.1
Frendeus, B.2
Jansson, B.3
Soderberg, I.4
Ljungcrantz, I.5
Araya, Z.6
Shah, P.K.7
Carlsson, R.8
Nilsson, J.9
Fredrikson, G.N.10
-
54
-
-
77958125881
-
Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis
-
Kyaw, T. et al. Conventional B2 B cell depletion ameliorates whereas its adoptive transfer aggravates atherosclerosis. J. Immunol. 185, 4410-4419 (2010).
-
(2010)
J. Immunol.
, vol.185
, pp. 4410-4419
-
-
Kyaw, T.1
-
55
-
-
77954914191
-
B cell depletion reduces the development of atherosclerosis in mice
-
Ait-Oufella, H. et al. B cell depletion reduces the development of atherosclerosis in mice. J. Exp. Med. 207, 1579-1587 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1579-1587
-
-
Ait-Oufella, H.1
-
56
-
-
0035045314
-
Network of vascular-associated dendritic cells in intima of healthy young individuals
-
Millonig, G. et al. Network of vascular-associated dendritic cells in intima of healthy young individuals. Arterioscler. Thromb. Vasc. Biol. 21, 503-508 (2001). (Pubitemid 32323380)
-
(2001)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.21
, Issue.4
, pp. 503-508
-
-
Millonig, G.1
Niederegger, H.2
Rabl, W.3
Hochleitner, B.W.4
Hoefer, D.5
Romani, N.6
Wick, G.7
-
57
-
-
33748469407
-
Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis
-
DOI 10.1084/jem.20060245
-
Jongstra-Bilen, J. et al. Low-grade chronic inflammation in regions of the normal mouse arterial intima predisposed to atherosclerosis. J. Exp. Med. 203, 2073-2083 (2006). (Pubitemid 44352229)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.9
, pp. 2073-2083
-
-
Jongstra-Bilen, J.1
Haidari, M.2
Zhu, S.-N.3
Chen, M.4
Guha, D.5
Cybulsky, M.I.6
-
58
-
-
63449086433
-
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
-
Choi, J.H. et al. Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves. J. Exp. Med. 206, 497-505 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 497-505
-
-
Choi, J.H.1
-
59
-
-
33646692002
-
Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent
-
DOI 10.1084/jem.20052205
-
Galkina, E. et al. Lymphocyte recruitment into the aortic wall before and during development of atherosclerosis is partially L-selectin dependent. J. Exp. Med. 203, 1273-1282 (2006). (Pubitemid 43736596)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.5
, pp. 1273-1282
-
-
Galkina, E.1
Kadl, A.2
Sanders, J.3
Varughese, D.4
Sarembock, I.J.5
Ley, K.6
-
60
-
-
38549149964
-
CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden
-
DOI 10.1161/ATVBAHA.107.158675, PII 0004360520080200000007
-
Liu, P. et al. CX3CR1 deficiency impairs dendritic cell accumulation in arterial intima and reduces atherosclerotic burden. Arterioscler. Thromb. Vasc. Biol. 28, 243-250 (2008). (Pubitemid 351161195)
-
(2008)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.28
, Issue.2
, pp. 243-250
-
-
Liu, P.1
Yu, Y.-R.A.2
Spencer, J.A.3
Johnson, A.E.4
Vallanat, C.T.5
Fong, A.M.6
Patterson, C.7
Patel, D.D.8
-
61
-
-
67249131192
-
Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia
-
Wu, H. et al. Functional role of CD11c+ monocytes in atherogenesis associated with hypercholesterolemia. Circulation 119, 2708-2717 (2009).
-
(2009)
Circulation
, vol.119
, pp. 2708-2717
-
-
Wu, H.1
-
62
-
-
33847080411
-
Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions
-
Shaposhnik, Z., Wang, X., Weinstein, M., Bennett, B.J. & Lusis, A.J. Granulocyte macrophage colony-stimulating factor regulates dendritic cell content of atherosclerotic lesions. Arterioscler. Thromb. Vasc. Biol. 27, 621-627 (2007).
-
(2007)
Arterioscler. Thromb. Vasc. Biol.
, vol.27
, pp. 621-627
-
-
Shaposhnik, Z.1
Wang, X.2
Weinstein, M.3
Bennett, B.J.4
Lusis, A.J.5
-
63
-
-
70350455635
-
GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions
-
Zhu, S.N., Chen, M., Jongstra-Bilen, J. & Cybulsky, M.I. GM-CSF regulates intimal cell proliferation in nascent atherosclerotic lesions. J. Exp. Med. 206, 2141-2149 (2009).
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2141-2149
-
-
Zhu, S.N.1
Chen, M.2
Jongstra-Bilen, J.3
Cybulsky, M.I.4
-
64
-
-
76349096459
-
Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis
-
Paulson, K.E. et al. Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis. Circ. Res. 106, 383-390 (2010).
-
(2010)
Circ. Res.
, vol.106
, pp. 383-390
-
-
Paulson, K.E.1
-
65
-
-
5644273775
-
Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization
-
DOI 10.1016/j.immuni.2004.09.003, PII S1074761304002766
-
Angeli, V. et al. Dyslipidemia associated with atherosclerotic disease systemically alters dendritic cell mobilization. Immunity 21, 561-574 (2004). (Pubitemid 39370511)
-
(2004)
Immunity
, vol.21
, Issue.4
, pp. 561-574
-
-
Angeli, V.1
Llodra, J.2
Rong, J.X.3
Satoh, K.4
Ishii, S.5
Shimizu, T.6
Fisher, E.A.7
Randolph, G.J.8
-
66
-
-
66349115961
-
Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis
-
Gautier, E.L. et al. Conventional dendritic cells at the crossroads between immunity and cholesterol homeostasis in atherosclerosis. Circulation 119, 2367-2375 (2009).
-
(2009)
Circulation
, vol.119
, pp. 2367-2375
-
-
Gautier, E.L.1
-
67
-
-
40949138918
-
Vessel wall-embedded dendritic cells induce T-cell autoreactivity and initiate vascular inflammation
-
DOI 10.1161/CIRCRESAHA.107.161653
-
Han, J.W. et al. Vessel wall-embedded dendritic cells induce T cell autoreactivity and initiate vascular inflammation. Circ. Res. 102, 546-553 (2008). (Pubitemid 351416755)
-
(2008)
Circulation Research
, vol.102
, Issue.5
, pp. 546-553
-
-
Han, J.W.1
Shimada, K.2
Ma-Krupa, W.3
Johnson, T.L.4
Nerem, R.M.5
Goronzy, J.J.6
Weyand, C.M.7
-
68
-
-
35648992465
-
Synergistic proinflammatory effects of the antiviral cytokine interferon-α and toll-like receptor 4 ligands in the atherosclerotic plaque
-
DOI 10.1161/CIRCULATIONAHA.107.697789
-
Niessner, A. et al. Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaque. Circulation 116, 2043-2052 (2007). (Pubitemid 350023750)
-
(2007)
Circulation
, vol.116
, Issue.18
, pp. 2043-2052
-
-
Niessner, A.1
Shin, M.S.2
Pryshchep, O.3
Goronzy, J.J.4
Chaikof, E.L.5
Weyand, C.M.6
-
69
-
-
33845428041
-
Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T-cell function in the atherosclerotic plaque through interferon-α
-
DOI 10.1161/CIRCULATIONAHA.106.642801, PII 0000301720061205000011
-
Niessner, A. et al. Pathogen-sensing plasmacytoid dendritic cells stimulate cytotoxic T cell function in the atherosclerotic plaque through interferon-α. Circulation 114, 2482-2489 (2006). (Pubitemid 44901521)
-
(2006)
Circulation
, vol.114
, Issue.23
, pp. 2482-2489
-
-
Niessner, A.1
Sato, K.2
Chaikof, E.L.3
Colmegna, I.4
Goronzy, J.J.5
Weyand, C.M.6
-
70
-
-
77956180166
-
Myeloid type i interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions
-
Goossens, P. et al. Myeloid type I interferon signaling promotes atherosclerosis by stimulating macrophage recruitment to lesions. Cell Metab. 12, 142-153 (2010).
-
(2010)
Cell Metab.
, vol.12
, pp. 142-153
-
-
Goossens, P.1
-
71
-
-
68549099805
-
Macrophage migration inhibitory factor: A noncanonical chemokine important in atherosclerosis
-
Noels, H., Bernhagen, J. & Weber, C. Macrophage migration inhibitory factor: a noncanonical chemokine important in atherosclerosis. Trends Cardiovasc. Med. 19, 76-86 (2009).
-
(2009)
Trends Cardiovasc. Med.
, vol.19
, pp. 76-86
-
-
Noels, H.1
Bernhagen, J.2
Weber, C.3
-
72
-
-
58149345643
-
T cell costimulation and coinhibition in atherosclerosis
-
Gotsman, I., Sharpe, A.H. & Lichtman, A.H. T cell costimulation and coinhibition in atherosclerosis. Circ. Res. 103, 1220-1231 (2008).
-
(2008)
Circ. Res.
, vol.103
, pp. 1220-1231
-
-
Gotsman, I.1
Sharpe, A.H.2
Lichtman, A.H.3
-
73
-
-
70350447306
-
The multi-functionality of CD40L and its receptor CD40 in atherosclerosis
-
Lievens, D., Eijgelaar, W.J., Biessen, E.A., Daemen, M.J. & Lutgens, E. The multi-functionality of CD40L and its receptor CD40 in atherosclerosis. Thromb. Haemost. 102, 206-214 (2009).
-
(2009)
Thromb. Haemost.
, vol.102
, pp. 206-214
-
-
Lievens, D.1
Eijgelaar, W.J.2
Biessen, E.A.3
Daemen, M.J.4
Lutgens, E.5
-
74
-
-
78549272749
-
Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
-
Lievens, D. et al. Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis. Blood 116, 4317-4327 (2010).
-
(2010)
Blood
, vol.116
, pp. 4317-4327
-
-
Lievens, D.1
-
75
-
-
77149136451
-
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
-
Lutgens, E. et al. Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile. J. Exp. Med. 207, 391-404 (2010).
-
(2010)
J. Exp. Med.
, vol.207
, pp. 391-404
-
-
Lutgens, E.1
-
76
-
-
66349136862
-
The macrophage scavenger receptor at 30 years of age: Current knowledge and future challenges
-
Greaves, D.R. & Gordon, S. The macrophage scavenger receptor at 30 years of age: current knowledge and future challenges. J. Lipid Res. 50 (suppl.), S282-S286 (2009).
-
(2009)
J. Lipid Res.
, vol.50
, Issue.SUPPL.
-
-
Greaves, D.R.1
Gordon, S.2
-
77
-
-
58849161736
-
Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice
-
Manning-Tobin, J.J. et al. Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice. Arterioscler. Thromb. Vasc. Biol. 29, 19-26 (2009).
-
(2009)
Arterioscler. Thromb. Vasc. Biol.
, vol.29
, pp. 19-26
-
-
Manning-Tobin, J.J.1
-
78
-
-
75649087741
-
CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
-
Stewart, C.R. et al. CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer. Nat. Immunol. 11, 155-161 (2010).
-
(2010)
Nat. Immunol.
, vol.11
, pp. 155-161
-
-
Stewart, C.R.1
-
79
-
-
65349135431
-
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/-and Ldlr-/-mice lacking CHOP
-
Thorp, E. et al. Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/-and Ldlr-/-mice lacking CHOP. Cell Metab. 9, 474-481 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 474-481
-
-
Thorp, E.1
-
80
-
-
77950525966
-
Endoplasmic reticulum stress and atherosclerosis
-
Hotamisligil, G.S. Endoplasmic reticulum stress and atherosclerosis. Nat. Med. 16, 396-399 (2010).
-
(2010)
Nat. Med.
, vol.16
, pp. 396-399
-
-
Hotamisligil, G.S.1
-
81
-
-
71549152580
-
Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis
-
Erbay, E. et al. Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis. Nat. Med. 15, 1383-1391 (2009).
-
(2009)
Nat. Med.
, vol.15
, pp. 1383-1391
-
-
Erbay, E.1
-
82
-
-
36849011221
-
Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice
-
DOI 10.1172/JCI33372
-
Yvan-Charvet, L. et al. Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. J. Clin. Invest. 117, 3900-3908 (2007). (Pubitemid 350224099)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.12
, pp. 3900-3908
-
-
Yvan-Charvet, L.1
Ranalletta, M.2
Wang, N.3
Han, S.4
Terasaka, N.5
Li, R.6
Welch, C.7
Tall, A.R.8
-
83
-
-
77954039619
-
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation
-
Yvan-Charvet, L. et al. ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. Science 328, 1689-1693 (2010).
-
(2010)
Science
, vol.328
, pp. 1689-1693
-
-
Yvan-Charvet, L.1
-
84
-
-
78049422010
-
Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice
-
Wang, F. et al. Sphingosine-1-phosphate receptor-2 deficiency leads to inhibition of macrophage proinflammatory activities and atherosclerosis in apoE-deficient mice. J. Clin. Invest. 120, 3979-3995 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3979-3995
-
-
Wang, F.1
-
85
-
-
77951800951
-
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
-
Duewell, P. et al. NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature 464, 1357-1361 (2010).
-
(2010)
Nature
, vol.464
, pp. 1357-1361
-
-
Duewell, P.1
-
86
-
-
77955356552
-
Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: A novel link between cholesterol metabolism and inflammation
-
Rajamäki, K. et al. Cholesterol crystals activate the NLRP3 inflammasome in human macrophages: a novel link between cholesterol metabolism and inflammation. PLoS ONE 5, e11765 (2010).
-
(2010)
PLoS ONE
, vol.5
-
-
Rajamäki, K.1
-
87
-
-
79959999614
-
Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
-
Menu, P. et al. Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome. Cell Death Dis. 2, e137 (2011).
-
(2011)
Cell Death Dis.
, vol.2
-
-
Menu, P.1
-
88
-
-
78650194817
-
Lp-PLA-a novel risk factor for high-risk coronary and carotid artery disease
-
Epps, K.C. & Wilensky, R.L. Lp-PLA-a novel risk factor for high-risk coronary and carotid artery disease. J. Intern. Med. 269, 94-106 (2011).
-
(2011)
J. Intern. Med.
, vol.269
, pp. 94-106
-
-
Epps, K.C.1
Wilensky, R.L.2
-
89
-
-
53549093853
-
Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
-
Wilensky, R.L. et al. Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development. Nat. Med. 14, 1059-1066 (2008).
-
(2008)
Nat. Med.
, vol.14
, pp. 1059-1066
-
-
Wilensky, R.L.1
-
90
-
-
79952070468
-
Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/PAF acetylhydrolase
-
Liu, J. et al. Circulating platelet-activating factor is primarily cleared by transport, not intravascular hydrolysis by lipoprotein-associated phospholipase A2/PAF acetylhydrolase. Circ. Res. 108, 469-477 (2011).
-
(2011)
Circ. Res.
, vol.108
, pp. 469-477
-
-
Liu, J.1
-
91
-
-
0033536049
-
Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions
-
DOI 10.1073/pnas.96.12.6931
-
Siess, W. et al. Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions. Proc. Natl. Acad. Sci. USA 96, 6931-6936 (1999). (Pubitemid 29274987)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.12
, pp. 6931-6936
-
-
Siess, W.1
Zangl, K.J.2
Essler, M.3
Bauer, M.4
Brandl, R.5
Corrinth, C.6
Bittman, R.7
Tigyi, G.8
Aepfelbacher, M.9
-
92
-
-
79955596968
-
Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium
-
Zhou, Z. et al. Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium. Cell Metab. 13, 592-600 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 592-600
-
-
Zhou, Z.1
-
93
-
-
77955505564
-
Biological, clinical and population relevance of 95 loci for blood lipids
-
Teslovich, T.M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707-713 (2010).
-
(2010)
Nature
, vol.466
, pp. 707-713
-
-
Teslovich, T.M.1
-
94
-
-
78651323379
-
Genetics of myocardial infarction: A progress report
-
Schunkert, H., Erdmann, J. & Samani, N.J. Genetics of myocardial infarction: a progress report. Eur. Heart J. 31, 918-925 (2010).
-
(2010)
Eur. Heart J.
, vol.31
, pp. 918-925
-
-
Schunkert, H.1
Erdmann, J.2
Samani, N.J.3
-
95
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Kathiresan, S. et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat. Genet. 41, 334-341 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
-
96
-
-
78049314943
-
A multilocus genetic risk score for coronary heart disease: Case-control and prospective cohort analyses
-
Ripatti, S. et al. A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses. Lancet 376, 1393-1400 (2010).
-
(2010)
Lancet
, vol.376
, pp. 1393-1400
-
-
Ripatti, S.1
-
97
-
-
79953204259
-
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
-
Schunkert, H. et al. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat. Genet. 43, 333-338 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 333-338
-
-
Schunkert, H.1
-
98
-
-
79953221100
-
Genetics Consortium. A Genome-wide Association Study in Europeans and South Asians Identifies Five New Loci for Coronary Artery Disease
-
Coronary Artery Disease (C4D)
-
Coronary Artery Disease (C4D) Genetics Consortium. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nat. Genet. 43, 339-344 (2011).
-
(2011)
Nat. Genet.
, vol.43
, pp. 339-344
-
-
-
99
-
-
79951473520
-
9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response
-
Harismendy, O. et al. 9p21 DNA variants associated with coronary artery disease impair interferon-gamma signalling response. Nature 470, 264-268 (2011).
-
(2011)
Nature
, vol.470
, pp. 264-268
-
-
Harismendy, O.1
-
100
-
-
79954476985
-
The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels
-
Mehta, N.N. et al. The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels. Eur. Heart J. 32, 963-971 (2011).
-
(2011)
Eur. Heart J.
, vol.32
, pp. 963-971
-
-
Mehta, N.N.1
-
101
-
-
0036645577
-
Stromal cell-derived factor-1α in unstable angina potential antiinflammatory and matrix-stabilizing effects
-
DOI 10.1161/01.CIR.0000020001.09990.90
-
Damås, J.K. et al. Stromal cell-derived factor-1alpha in unstable angina: potential antiinflammatory and matrix-stabilizing effects. Circulation 106, 36-42 (2002). (Pubitemid 34747439)
-
(2002)
Circulation
, vol.106
, Issue.1
, pp. 36-42
-
-
Damas, J.K.1
Waehre, T.2
Yndestad, A.3
Ueland, T.4
Muller, F.5
Eiken, H.G.6
Holm, A.M.7
Halvorsen, B.8
Froland, S.S.9
Gullestad, L.10
Aukrust, P.11
-
102
-
-
78650419962
-
Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis
-
Kiechl, S. et al. Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 30, 2678-2683 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 2678-2683
-
-
Kiechl, S.1
-
103
-
-
77449127999
-
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection
-
Zernecke, A. et al. Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci. Signal. 2, ra81 (2009).
-
(2009)
Sci. Signal.
, vol.2
-
-
Zernecke, A.1
-
104
-
-
40349103409
-
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
-
DOI 10.1073/pnas.0707493105
-
Harris, T.A., Yamakuchi, M., Ferlito, M., Mendell, J.T. & Lowenstein, C.J. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc. Natl. Acad. Sci. USA 105, 1516-1521 (2008). (Pubitemid 351346546)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1516-1521
-
-
Harris, T.A.1
Yamakuchi, M.2
Ferlito, M.3
Mendell, J.T.4
Lowenstein, C.J.5
-
105
-
-
77957028990
-
Circulating microRNAs in patients with coronary artery disease
-
Fichtlscherer, S. et al. Circulating microRNAs in patients with coronary artery disease. Circ. Res. 107, 677-684 (2010).
-
(2010)
Circ. Res.
, vol.107
, pp. 677-684
-
-
Fichtlscherer, S.1
-
106
-
-
79953733693
-
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
-
Wang, Z. et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature 472, 57-63 (2011).
-
(2011)
Nature
, vol.472
, pp. 57-63
-
-
Wang, Z.1
-
107
-
-
19644362702
-
Effects of antibiotic therapy on outcomes of patients with coronary artery disease: A meta-analysis of randomized controlled trials
-
DOI 10.1001/jama.293.21.2641
-
Andraws, R., Berger, J.S. & Brown, D.L. Effects of antibiotic therapy on outcomes of patients with coronary artery disease: a meta-analysis of randomized controlled trials. J. Am. Med. Assoc. 293, 2641-2647 (2005). (Pubitemid 40741201)
-
(2005)
Journal of the American Medical Association
, vol.293
, Issue.21
, pp. 2641-2647
-
-
Andraws, R.1
Berger, J.S.2
Brown, D.L.3
-
108
-
-
26844564725
-
The potential relevance of the multiple lipid-independent (Pleiotropic) effects of statins in the management of acute coronary syndromes
-
DOI 10.1016/j.jacc.2005.05.086, PII S0735109705017730
-
Ray, K.K. & Cannon, C.P. The potential relevance of the multiple lipid-independent (pleiotropic) effects of statins in the management of acute coronary syndromes. J. Am. Coll. Cardiol. 46, 1425-1433 (2005). (Pubitemid 41446176)
-
(2005)
Journal of the American College of Cardiology
, vol.46
, Issue.8
, pp. 1425-1433
-
-
Ray, K.K.1
Cannon, C.P.2
-
109
-
-
23944443325
-
Effect of intensive lipid lowering on progression of coronary atherosclerosis: Evidence for an early benefit from the reversal of atherosclerosis with aggressive lipid lowering (REVERSAL) trial
-
DOI 10.1016/j.amjcard.2005.07.013, PII S0002914905011379
-
Nissen, S.E. Effect of intensive lipid lowering on progression of coronary atherosclerosis: evidence for an early benefit from the Reversal of Atherosclerosis with Aggressive Lipid Lowering (REVERSAL) trial. Am. J. Cardiol. 96, 61F-68F (2005). (Pubitemid 41207735)
-
(2005)
American Journal of Cardiology
, vol.96
, Issue.5 SUPPL.
-
-
Nissen, S.E.1
-
110
-
-
63649095045
-
Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: A prospective study of the JUPITER trial
-
Ridker, P.M. et al. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet 373, 1175-1182 (2009).
-
(2009)
Lancet
, vol.373
, pp. 1175-1182
-
-
Ridker, P.M.1
-
111
-
-
72049129430
-
Extended-release niacin or ezetimibe and carotid intima-media thickness
-
Taylor, A.J. et al. Extended-release niacin or ezetimibe and carotid intima-media thickness. N. Engl. J. Med. 361, 2113-2122 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2113-2122
-
-
Taylor, A.J.1
-
112
-
-
79952240405
-
Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells
-
Lukasova, M., Malaval, C., Gille, A., Kero, J. & Offermanns, S. Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. J. Clin. Invest. 121, 1163-1173 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1163-1173
-
-
Lukasova, M.1
Malaval, C.2
Gille, A.3
Kero, J.4
Offermanns, S.5
-
113
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin, L. et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N. Engl. J. Med. 361, 1045-1057 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1045-1057
-
-
Wallentin, L.1
-
114
-
-
33846118743
-
Platelets as immune cells: Bridging inflammation and cardiovascular disease
-
DOI 10.1161/01.RES.0000252802.25497.b7, PII 0000301220070105000007
-
von Hundelshausen, P. & Weber, C. Platelets as immune cells: bridging inflammation and cardiovascular disease. Circ. Res. 100, 27-40 (2007). (Pubitemid 46066771)
-
(2007)
Circulation Research
, vol.100
, Issue.1
, pp. 27-40
-
-
Von Hundelshausen, P.1
Weber, C.2
-
115
-
-
34447260981
-
β-blockers and progression of coronary atherosclerosis: Pooled analysis of 4 intravascular ultrasonography trials
-
Sipahi, I. et al. Beta-blockers and progression of coronary atherosclerosis: pooled analysis of 4 intravascular ultrasonography trials. Ann. Intern. Med. 147, 10-18 (2007). (Pubitemid 351664629)
-
(2007)
Annals of Internal Medicine
, vol.147
, Issue.1
, pp. 10-18
-
-
Sipahi, I.1
Tuzcu, E.M.2
Wolski, K.E.3
Nicholls, S.J.4
Schoenhagen, P.5
Hu, B.6
Balog, C.7
Shishehbor, M.8
Magyar, W.A.9
Crowe, T.D.10
Kapadia, S.11
Nissen, S.E.12
-
116
-
-
42049107348
-
Telmisartan, ramipril, or both in patients at high risk for vascular events
-
DOI 10.1056/NEJMoa0801317
-
Yusuf, S. et al. Telmisartan, ramipril, or both in patients at high risk for vascular events. N. Engl. J. Med. 358, 1547-1559 (2008). (Pubitemid 351522739)
-
(2008)
New England Journal of Medicine
, vol.358
, Issue.15
, pp. 1547-1559
-
-
Yusuf, S.1
Teo, K.K.2
Pogue, J.3
Dyal, L.4
Copland, I.5
Schumacher, H.6
Dagenais, G.7
Sleight, P.8
Anderson, C.9
-
117
-
-
0242577955
-
Effect of Recombinant ApoA-I Milano on Coronary Atherosclerosis in Patients with Acute Coronary Syndromes: A Randomized Controlled Trial
-
DOI 10.1001/jama.290.17.2292
-
Nissen, S.E. et al. Effect of recombinant ApoA-I Milano on coronary atherosclerosis in patients with acute coronary syndromes: a randomized controlled trial. J. Am. Med. Assoc. 290, 2292-2300 (2003). (Pubitemid 37430562)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.17
, pp. 2292-2300
-
-
Nissen, S.E.1
Tsunoda, T.2
Tuzcu, E.M.3
Schoenhagen, P.4
Cooper, C.J.5
Yasin, M.6
Eaton, G.M.7
Lauer, M.A.8
Sheldon, W.S.9
Grines, C.L.10
Halpern, S.11
Crowe, T.12
Blankenship, J.C.13
Kerensky, R.14
-
118
-
-
75149146582
-
Structure and function of HDL mimetics
-
Navab, M. et al. Structure and function of HDL mimetics. Arterioscler. Thromb. Vasc. Biol. 30, 164-168 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 164-168
-
-
Navab, M.1
-
119
-
-
54049152760
-
Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque
-
Serruys, P.W. et al. Effects of the direct lipoprotein-associated phospholipase A(2) inhibitor darapladib on human coronary atherosclerotic plaque. Circulation 118, 1172-1182 (2008).
-
(2008)
Circulation
, vol.118
, pp. 1172-1182
-
-
Serruys, P.W.1
-
120
-
-
58849141318
-
Direct antiatherosclerotic effects of PPAR agonists
-
Jandeleit-Dahm, K.A., Calkin, A., Tikellis, C. & Thomas, M. Direct antiatherosclerotic effects of PPAR agonists. Curr. Opin. Lipidol. 20, 24-29 (2009).
-
(2009)
Curr. Opin. Lipidol.
, vol.20
, pp. 24-29
-
-
Jandeleit-Dahm, K.A.1
Calkin, A.2
Tikellis, C.3
Thomas, M.4
-
121
-
-
67149146438
-
Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): A multicentre, randomised, open-label trial
-
Home, P.D. et al. Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial. Lancet 373, 2125-2135 (2009).
-
(2009)
Lancet
, vol.373
, pp. 2125-2135
-
-
Home, P.D.1
-
122
-
-
77955285732
-
Rosiglitazone revisited: An updated meta-analysis of risk for myocardial infarction and cardiovascular mortality
-
Nissen, S.E. & Wolski, K. Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality. Arch. Intern. Med. 170, 1191-1201 (2010).
-
(2010)
Arch. Intern. Med.
, vol.170
, pp. 1191-1201
-
-
Nissen, S.E.1
Wolski, K.2
-
123
-
-
34548590934
-
Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of randomized trials
-
DOI 10.1001/jama.298.10.1180
-
Lincoff, A.M., Wolski, K., Nicholls, S.J. & Nissen, S.E. Pioglitazone and risk of cardiovascular events in patients with type 2 diabetes mellitus: a meta-analysis of randomized trials. J. Am. Med. Assoc. 298, 1180-1188 (2007). (Pubitemid 47403104)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.10
, pp. 1180-1188
-
-
Lincoff, A.M.1
Wolski, K.2
Nicholls, S.J.3
Nissen, S.E.4
-
124
-
-
41649090426
-
Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: The STRADIVARIUS randomized controlled trial
-
DOI 10.1001/jama.299.13.1547
-
Nissen, S.E. et al. Effect of rimonabant on progression of atherosclerosis in patients with abdominal obesity and coronary artery disease: the STRADIVARIUS randomized controlled trial. J. Am. Med. Assoc. 299, 1547-1560 (2008). (Pubitemid 351482794)
-
(2008)
JAMA - Journal of the American Medical Association
, vol.299
, Issue.13
, pp. 1547-1560
-
-
Nissen, S.E.1
Nicholls, S.J.2
Wolski, K.3
Rodes-Cabau, J.4
Cannon, C.P.5
Deanfield, J.E.6
Despres, J.-P.7
Kastelein, J.J.P.8
Steinhubl, S.R.9
Kapadia, S.10
Yasin, M.11
Ruzyllo, W.12
Gaudin, C.13
Job, B.14
Hu, B.15
Bhatt, D.L.16
Lincoff, A.M.17
Tuzcu, E.M.18
-
125
-
-
58149386896
-
Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: Insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation)
-
Nicholls, S.J., Tuzcu, E.M., Brennan, D.M., Tardif, J.C. & Nissen, S.E. Cholesteryl ester transfer protein inhibition, high-density lipoprotein raising, and progression of coronary atherosclerosis: insights from ILLUSTRATE (Investigation of Lipid Level Management Using Coronary Ultrasound to Assess Reduction of Atherosclerosis by CETP Inhibition and HDL Elevation). Circulation 118, 2506-2514 (2008).
-
(2008)
Circulation
, vol.118
, pp. 2506-2514
-
-
Nicholls, S.J.1
Tuzcu, E.M.2
Brennan, D.M.3
Tardif, J.C.4
Nissen, S.E.5
-
126
-
-
71549121695
-
Treating inflammation in atherosclerotic cardiovascular disease: Emerging therapies
-
Klingenberg, R. & Hansson, G.K. Treating inflammation in atherosclerotic cardiovascular disease: emerging therapies. Eur. Heart J. 30, 2838-2844 (2009).
-
(2009)
Eur. Heart J.
, vol.30
, pp. 2838-2844
-
-
Klingenberg, R.1
Hansson, G.K.2
-
127
-
-
55849139457
-
Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment
-
Weber, C. et al. Structural determinants of MIF functions in CXCR2-mediated inflammatory and atherogenic leukocyte recruitment. Proc. Natl. Acad. Sci. USA 105, 16278-16283 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 16278-16283
-
-
Weber, C.1
-
128
-
-
79954573511
-
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism
-
Kraemer, S. et al. MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism. FASEB J. 25, 894-906 (2011).
-
(2011)
FASEB J.
, vol.25
, pp. 894-906
-
-
Kraemer, S.1
-
130
-
-
78449282952
-
A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice
-
Liehn, E.A. et al. A new monocyte chemotactic protein-1/chemokine CC motif ligand-2 competitor limiting neointima formation and myocardial ischemia/reperfusion injury in mice. J. Am. Coll. Cardiol. 56, 1847-1857 (2010).
-
(2010)
J. Am. Coll. Cardiol.
, vol.56
, pp. 1847-1857
-
-
Liehn, E.A.1
-
131
-
-
44849104301
-
A novel RANTES antagonist prevents progression of established atherosclerotic lesions in mice
-
Braunersreuther, V. et al. A novel RANTES antagonist prevents progression of established atherosclerotic lesions in mice. Arterioscler. Thromb. Vasc. Biol. 28, 1090-1096 (2008).
-
(2008)
Arterioscler. Thromb. Vasc. Biol.
, vol.28
, pp. 1090-1096
-
-
Braunersreuther, V.1
-
132
-
-
77950022563
-
Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe-/-mice
-
Hjerpe, C., Johansson, D., Hermansson, A., Hansson, G.K. & Zhou, X. Dendritic cells pulsed with malondialdehyde modified low density lipoprotein aggravate atherosclerosis in Apoe-/-mice. Atherosclerosis 209, 436-441 (2010).
-
(2010)
Atherosclerosis
, vol.209
, pp. 436-441
-
-
Hjerpe, C.1
Johansson, D.2
Hermansson, A.3
Hansson, G.K.4
Zhou, X.5
-
133
-
-
74249123382
-
Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice
-
Habets, K.L. et al. Vaccination using oxidized low-density lipoprotein-pulsed dendritic cells reduces atherosclerosis in LDL receptor-deficient mice. Cardiovasc. Res. 85, 622-630 (2010).
-
(2010)
Cardiovasc. Res.
, vol.85
, pp. 622-630
-
-
Habets, K.L.1
-
134
-
-
79953037006
-
Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice
-
Hermansson, A. et al. Immunotherapy with tolerogenic apolipoprotein B-100-loaded dendritic cells attenuates atherosclerosis in hypercholesterolemic mice. Circulation 123, 1083-1091 (2011).
-
(2011)
Circulation
, vol.123
, pp. 1083-1091
-
-
Hermansson, A.1
-
135
-
-
77951433369
-
Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis
-
Klingenberg, R. et al. Intranasal immunization with an apolipoprotein B-100 fusion protein induces antigen-specific regulatory T cells and reduces atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 30, 946-952 (2010).
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 946-952
-
-
Klingenberg, R.1
|