Characterization of Regulatory Elements on the Promoter Region of p16 INK4a That Contribute to Overexpression of p16 in Senescent Fibroblasts

Journal of Biological Chemistry

Volumn 276, Issue 52, 2001, Pages 48655-48661

  Wang, Wei ^a   Wu, Junfeng ^a   Zhang, Zongyu ^a   Tong, Tanjun ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES;

SENESCENCE;

BIOCHEMISTRY;

CYCLIN DEPENDENT KINASE INHIBITOR; DEOXYRIBONUCLEASE I; GREEN FLUORESCENT PROTEIN; HELIX LOOP HELIX PROTEIN; MESSENGER RNA; NUCLEAR FACTOR; PHOSPHORUS 32; PROTEIN P16; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS 2; DYES, REAGENTS, INDICATORS, MARKERS AND BUFFERS; PHOTOPROTEIN;

ANIMAL CELL; ARTICLE; CELL AGING; DELETION MUTANT; DNA SEQUENCE; FIBROBLAST; GENE OVEREXPRESSION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETIC TRANSDUCTION; INK4A TRANSCRIPTION SILENCE ELEMENT; ISOTOPE LABELING; MONOLAYER CULTURE; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA INTERACTION; RETROVIRUS; SENESCENCE; SITE DIRECTED MUTAGENESIS; SOUTHWESTERN BLOTTING; TRANSCRIPTION REGULATION; TRANSCRIPTION REGULATORY ELEMENT; CELL LINE; CYTOLOGY; DNA FOOTPRINTING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LUNG; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REPORTER GENE;

ANIMALIA; UNIDENTIFIED RETROVIRUS;

BASE SEQUENCE; CELL AGING; CELL LINE; DNA FOOTPRINTING; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMAN; INDICATORS AND REAGENTS; LUMINESCENT PROTEINS; LUNG; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); PROTEIN P16; SUPPORT, NON-U.S. GOV'T;

EID: 0035966101     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M108278200     Document Type: Article

References (38)

1. Hayflick, L., and Moorhead, P. S. (1965) Exp. Cell Res. 25, 585-621
2. Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., and Barrett, J. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 13742-13747
3. Hara, E., Smith, R., Parry, D., Tahara, H., Stone, S., and Peters, G. (1996) Mol. Cell. Biol. 16, 859-867
4. Serrano, M., Hannon, G. J., and Beach, D. (1993) Nature 366, 704-707
5. Adrian, G. S., Seto, E., Fischbach, K. S., Rivera, E. V., Adrian, E. K., Herbert, D. C., Walter, C. A., Weaker, F. J., and Bowman, B. H. (1996) J. Gerontol. A Biol. Sci. Med. Sci. 51, B66-B75
6. Zindy, F., Quelle, D. E., Roussel, M. F., and Sherr, C. J. (1997) Oncogene 15, 203-211
7. Huschtscha, L. I., and Reddel, R. R. (1999) Carcinogenesis 20, 921-926
8. Jarrard, D. F., Sarker, S., Shi, Y., Yeager, T. R., Magrane, G., Kinoshita, H., Nassif, N., Meisner, L., Newton, M. A., Waldman, F. M., and Reznikoff, C. A. (1999) Cancer Res. 59, 2957-2964
9. Chen, P. L., Tong, T. J., and Zhang, Z. Y. (2001) Chin. J. Geriatr. 20, 44-46
10. Liu, P. H., Tong, T. J., Zhang Z. Y. (2001) Chin. J. Geriatr. 20, 128-131
11. Nielsen, G. P., Stemmer-Rachamimov, A. O., Shaw, J., Roy, J. E., Koh, J., and Louis, D. N. (1999) Lab. Invest. 79, 1137-1143
12. Serrano, M. (1997) Exp. Cell. Res. 237, 7-13
13. Kiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., and Klingelhutz, A. J. (1998) Nature 396, 84-88
14. Dickson, M. A., Hahn, W. C., Ino, Y., Ronfard, V., Wu, J. Y., Weinberg, R. A., Louis, D. N., Li, F. P., and Rheinwald, J. G. (2000) Mol. Cell. Biol. 20, 1436-1447
15. Jansen-Dürr, P. (1996) Trends Genet. 12, 270-275
16. Yeager, T. R., and Reddel, R. (1999) Curr. Opin. Biotech. 10, 465-469
17. Tang, Z., Zhang, Z., Zheng, Y., Corbley M. J., and Tong T. (1994) Mech. Aging Dev. 73, 57-67
18. Ausubel, F. M., Brent, R., Kingston R. E., Moore, D. D., Seidman, J. G., Smith, J. A., Struhl, K. (1992) Short Protocols in Molecular Biology, 2nd Ed., pp. 12-13-12-15, John Wiley & Sons, Inc., New York
19. Schnell, T., Foley, P., Wirth, M., Munch, J., and Uberla, K. (2000) Hum. Gene Ther. 11, 439-447
20. Stein, C. H., Drullinger, L. F., Soulard, A., and Dulic, V. (1999) Mol., Cell. Biol. 19, 2109-2117
21. Massari, M. E., and Murre, C. (2000) Mol. Cell. Biol. 20, 429-440
22. Lyden, D., Young, A. Z., Zagzag, D., Yan, W., Gerald, W., O'Reilly, R., Bader, B. L., Hynes, R. O., Zhuang, Y., Manova, K., and Benezra, R. (1999) Nature 401, 670-677
23. Ohtani, N., Zebedee, Z., Huot, T. H., Stinson, J. A., Sugimoto, M., Ohashi, Y., Sharrocks, A. D., Peters, G., and Hara, E. (2001) Nature 409, 1067-1070
24. Takai, N., Miyazaki, T., Fujisawa, K., Nasu, K., and Miyakawa, I. (2001) Cancer Lett. 165, 185-193
25. Courey, A. J., and Tjian, R. (1998) Cell 55, 887-898
26. Suske, G. (1999) Gene (Amst.) 238, 291-300
27. Courey, A. J., and Tjian, R. (1989) Cell 594, 827-836
28. Pavletich, N. P., and Pabo, C. O. (1991) Science 252, 809-817
29. Fairall, L., Schwabe, J. W., Chapman, L., Finch, J. T., and Rhodes, D. (1993) Nature 366, 483-487
30. Kingsley, C., and Winoto, A. (1992) Mol. Cell. Biol. 12, 4251-4261
31. Supp, D. M., Witte, D. P., Branford, W. W., Smith, E. P., and Potter, S. S. (1996) Dev. Biol. 176, 284-299
32. Zhao, L., and Chang, L. S. (1997) J. Biol. Chem. 272, 4869-4882
33. Ihn, H., and Trojanowska, M. (1997) Nucleic Acids Res. 25, 3712-3717
34. Kumar, A. P., and Butler, A. P. (1997) Nucleic Acids Res. 25, 2012-2019
35. Dennig, J., Beato, M., and Suske, G. (1996) EMBO J. 15, 5659-5667
36. Prowse, D. M., Bolgan, L., Molnar, A., and Dotto, G. P. (1997) J. Biol. Chem. 272, 1308-1314
37. Yamabe, Y., Shimamoto, A., Goto, M., Yokota, J., Sugawara, M., and Furuichi, Y. (1998) Mol. Cell. Biol. 18, 6191-6200
38. Fukami-Kobayashi, J., and Mitsui, Y. (1998) Exp. Cell Res. 241, 435-444