메뉴 건너뛰기




Volumn 2, Issue 6, 2012, Pages 418-436

Aptamer-conjugated polymeric nanoparticles for targeted cancer therapy

Author keywords

Antibodies; Aptamers; Cancer therapy; Nanoparticles; Polymers; Targeted Drug delivery

Indexed keywords

A 30; AGATOLIMOD; ANTINEOPLASTIC AGENT; ARC 245; AS 1411; CLONE 5; D 4; D 60; IMO 2055; MUC 1 TR 1 4; NANOPARTICLE; ODN 2006; PACLITAXEL; PEGAPTANIB; PLATELET DERIVED GROWTH FACTOR BB; POLYMER; TTA 1; UNCLASSIFIED DRUG; VASCULOTROPIN; VITRONECTIN RECEPTOR; XPSM A10; XPSM A9;

EID: 84869021184     PISSN: 2190393X     EISSN: 21903948     Source Type: Journal    
DOI: 10.1007/s13346-012-0104-0     Document Type: Review
Times cited : (18)

References (180)
  • 2
    • 51849084844 scopus 로고    scopus 로고
    • Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform
    • Zhang L, Chan JM, Gu FX, et al. Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano. 2008; 2: 1696-702.
    • (2008) ACS Nano , vol.2 , pp. 1696-1702
    • Zhang, L.1    Chan, J.M.2    Gu, F.X.3
  • 3
    • 42349094203 scopus 로고    scopus 로고
    • Nanoparticles in medicine: therapeutic applications and developments
    • Zhang L, et al. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther. 2008; 83: 761-9.
    • (2008) Clin Pharmacol Ther , vol.83 , pp. 761-769
    • Zhang, L.1
  • 4
    • 77957837775 scopus 로고    scopus 로고
    • Emerging technologies of polymeric nanoparticles in cancer drug delivery
    • 2011. doi: 10. 1155/2011/408675
    • Brewer E, Coleman J and Lowman A. Emerging technologies of polymeric nanoparticles in cancer drug delivery. J. Nanomaterials. 2011; 2011. doi: 10. 1155/2011/408675.
    • (2011) J. Nanomaterials.
    • Brewer, E.1    Coleman, J.2    Lowman, A.3
  • 5
    • 0036707316 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug delivery and targeting
    • Hans ML, Lowman AM. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci. 2002; 6: 319-27.
    • (2002) Curr Opin Solid State Mater Sci , vol.6 , pp. 319-327
    • Hans, M.L.1    Lowman, A.M.2
  • 6
    • 0030125278 scopus 로고    scopus 로고
    • Biodegradable polymeric materials
    • Chiellini E, Solaro R. Biodegradable polymeric materials. Adv Mater. 1996; 8: 305-13.
    • (1996) Adv Mater , vol.8 , pp. 305-313
    • Chiellini, E.1    Solaro, R.2
  • 7
    • 0001855042 scopus 로고
    • Controlled release of bioactive agents from lactide/glycolide polymers
    • M. Chasin and R. Langer (Eds.), New York: Marcel Dekker
    • Lewis DH. Controlled release of bioactive agents from lactide/glycolide polymers. In: Chasin M, Langer R, editors. Biodegradable polymers as drug delivery devices. New York: Marcel Dekker; 1990. p. 1-41.
    • (1990) Biodegradable Polymers as Drug Delivery Devices , pp. 1-41
    • Lewis, D.H.1
  • 8
    • 0001319478 scopus 로고    scopus 로고
    • Biodegradable block copolymers as injectable drug-delivery systems
    • Jeong B, Bae YH, Lee DS, Kim SW. Biodegradable block copolymers as injectable drug-delivery systems. Nature. 1997; 388: 860-2.
    • (1997) Nature , vol.388 , pp. 860-862
    • Jeong, B.1    Bae, Y.H.2    Lee, D.S.3    Kim, S.W.4
  • 9
    • 0343191443 scopus 로고    scopus 로고
    • Steakth corona-core nanoparticles surface modified by polyethylene glycol (PEG): influence of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption
    • Gref R, Luck M, Quellec P, et al. Steakth corona-core nanoparticles surface modified by polyethylene glycol (PEG): influence of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf B. 2000; 18: 301-13.
    • (2000) Colloids Surf B , vol.18 , pp. 301-313
    • Gref, R.1    Luck, M.2    Quellec, P.3
  • 10
    • 0034036366 scopus 로고    scopus 로고
    • Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles
    • Dunne M, Corrigan OI, Ramtoola Z. Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles. Biomaterials. 2000; 21: 1659-68.
    • (2000) Biomaterials , vol.21 , pp. 1659-1668
    • Dunne, M.1    Corrigan, O.I.2    Ramtoola, Z.3
  • 11
    • 9644252904 scopus 로고    scopus 로고
    • Size and temperature effects on poly (lactic-co-glycolic acid) degradation and microreservoir device performance
    • Grayson ACR, Cima MJ, Langer R. Size and temperature effects on poly (lactic-co-glycolic acid) degradation and microreservoir device performance. Biomaterials. 2005; 26: 2137-45.
    • (2005) Biomaterials , vol.26 , pp. 2137-2145
    • Grayson, A.C.R.1    Cima, M.J.2    Langer, R.3
  • 12
    • 0019559521 scopus 로고
    • Biodegradable polymers for use in surgeryopoly(glycolic)/poly(lactic acid) homo and copolymers: 2. In vitro degradation
    • Reed AM, Gilding DK. Biodegradable polymers for use in surgeryopoly(glycolic)/poly(lactic acid) homo and copolymers: 2. In vitro degradation. Polymer. 1981; 22: 494-8.
    • (1981) Polymer , vol.22 , pp. 494-498
    • Reed, A.M.1    Gilding, D.K.2
  • 13
    • 29544448116 scopus 로고    scopus 로고
    • Polymer conjugates:nanosized medicines for treating cancer
    • Vincent MJ, Duncan R. Polymer conjugates: nanosized medicines for treating cancer. Trends Biotechnol. 2006; 24: 39-47.
    • (2006) Trends Biotechnol , vol.24 , pp. 39-47
    • Vincent, M.J.1    Duncan, R.2
  • 14
    • 77956876990 scopus 로고    scopus 로고
    • Targeting cancer cells with nucleic acid aptamers
    • Cerchia L, de Franciscis V. Targeting cancer cells with nucleic acid aptamers. Trends Biotechnol. 2010; 28: 517-25.
    • (2010) Trends Biotechnol , vol.28 , pp. 517-525
    • Cerchia, L.1    de Franciscis, V.2
  • 15
    • 33846914204 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: RNA aptamers
    • Que-Gewirth NS, Sullenger BA. Gene therapy progress and prospects: RNA aptamers. Gene Ther. 2007; 14: 283-91.
    • (2007) Gene Ther , vol.14 , pp. 283-291
    • Que-Gewirth, N.S.1    Sullenger, B.A.2
  • 16
    • 0033790673 scopus 로고    scopus 로고
    • Escort aptamers: a delivery service for diagnosis and therapy
    • Hicke BJ, Stephens AW. Escort aptamers: a delivery service for diagnosis and therapy. J Clin Invest. 2000; 106: 923-38.
    • (2000) J Clin Invest , vol.106 , pp. 923-938
    • Hicke, B.J.1    Stephens, A.W.2
  • 17
    • 0027537022 scopus 로고
    • A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA
    • Wang KY, et al. A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA. Biochemistry. 1993; 32: 1899-904.
    • (1993) Biochemistry , vol.32 , pp. 1899-1904
    • Wang, K.Y.1
  • 18
    • 75449119505 scopus 로고    scopus 로고
    • Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach
    • Fang X, Tan W. Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach. Acc Chem Res. 2010; 43: 48-57.
    • (2010) Acc Chem Res , vol.43 , pp. 48-57
    • Fang, X.1    Tan, W.2
  • 19
    • 0031102380 scopus 로고    scopus 로고
    • Nucleic acid selection and the challenge of combinatorial chemistry
    • Osborne SE, Ellington AD. Nucleic acid selection and the challenge of combinatorial chemistry. Chem Rev. 1997; 97: 349-70.
    • (1997) Chem Rev , vol.97 , pp. 349-370
    • Osborne, S.E.1    Ellington, A.D.2
  • 20
    • 0031152065 scopus 로고    scopus 로고
    • Aptamers as therapeutic and diagnostic reagents: problems and prospects
    • Osborne SE, Matsumura I, Ellington AD. Aptamers as therapeutic and diagnostic reagents: problems and prospects. Curr Opin Chem Biol. 1997; 1: 5-9.
    • (1997) Curr Opin Chem Biol , vol.1 , pp. 5-9
    • Osborne, S.E.1    Matsumura, I.2    Ellington, A.D.3
  • 21
    • 35148840942 scopus 로고    scopus 로고
    • Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
    • Famulok M, Hartig JS, Mayer G. Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem Rev. 2007; 107: 3715-43.
    • (2007) Chem Rev , vol.107 , pp. 3715-3743
    • Famulok, M.1    Hartig, J.S.2    Mayer, G.3
  • 22
    • 33744548059 scopus 로고    scopus 로고
    • Nucleic acid aptamers and enzymes as sensors
    • Navani NK, Li Y. Nucleic acid aptamers and enzymes as sensors. Curr Opin Chem Biol. 2006; 10: 272-81.
    • (2006) Curr Opin Chem Biol , vol.10 , pp. 272-281
    • Navani, N.K.1    Li, Y.2
  • 24
    • 84869074783 scopus 로고    scopus 로고
    • Aptamers and cancer nanotechnology
    • In: Amiji MM, editor, Boca Raton: Taylor & Francis Group
    • Farokhzad OC, Jon S, Langer R. Aptamers and cancer nanotechnology. In: Amiji MM, editor. Nanotechnology for cancer therapy. Boca Raton: Taylor & Francis Group; 2006. pp. 289-313.
    • (2006) Nanotechnology for cancer therapy , pp. 289-313
    • Farokhzad, O.C.1    Jon, S.2    Langer, R.3
  • 25
    • 0034466813 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitrous humor of rhesus monkeys
    • Drolet DW, Nelson J, Tucker CE, et al. Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitrous humor of rhesus monkeys. Pharm Res. 2000; 17: 1503-10.
    • (2000) Pharm Res , vol.17 , pp. 1503-1510
    • Drolet, D.W.1    Nelson, J.2    Tucker, C.E.3
  • 28
    • 0042925463 scopus 로고    scopus 로고
    • Crystal structure of NF-kB (p50)2 complexed to a high-affinity RNA aptamer
    • Huang DB, et al. Crystal structure of NF-kB (p50)2 complexed to a high-affinity RNA aptamer. Proc Natl Acad Sci USA. 2003; 100: 9268-73.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9268-9273
    • Huang, D.B.1
  • 29
    • 33748335746 scopus 로고    scopus 로고
    • AGRO100 inhibits activation of nuclear factor-kappaB (NF-kB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin
    • Girvan AC, et al. AGRO100 inhibits activation of nuclear factor-kappaB (NF-kB) by forming a complex with NF-kappaB essential modulator (NEMO) and nucleolin. Mol Cancer Ther. 2006; 5: 1790-9.
    • (2006) Mol Cancer Ther , vol.5 , pp. 1790-1799
    • Girvan, A.C.1
  • 30
    • 42349106952 scopus 로고    scopus 로고
    • Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates
    • Zhang L, Radovic-Moreno AF, Alexis F, et al. Co-delivery of hydrophobic and hydrophilic drugs from nanoparticle-aptamer bioconjugates. ChemMedChem. 2007; 2: 1268-71.
    • (2007) ChemMedChem , vol.2 , pp. 1268-1271
    • Zhang, L.1    Radovic-Moreno, A.F.2    Alexis, F.3
  • 31
    • 0031279943 scopus 로고    scopus 로고
    • In vivo imagining of inflammation using an aptamer inhibitor of human neutrophil elastase
    • Charlton J, Sennello J, Smith D. In vivo imagining of inflammation using an aptamer inhibitor of human neutrophil elastase. Chem Biol. 1997; 4: 809-16.
    • (1997) Chem Biol , vol.4 , pp. 809-816
    • Charlton, J.1    Sennello, J.2    Smith, D.3
  • 32
    • 24744466474 scopus 로고    scopus 로고
    • Aptamers against extracellular targets for in vivo applications
    • Pestourie C, Tavitian B, Duconge F. Aptamers against extracellular targets for in vivo applications. Biochimie. 2005; 87: 921-30.
    • (2005) Biochimie , vol.87 , pp. 921-930
    • Pestourie, C.1    Tavitian, B.2    Duconge, F.3
  • 33
    • 33646580369 scopus 로고    scopus 로고
    • Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells
    • Herr JK, et al. Aptamer-conjugated nanoparticles for selective collection and detection of cancer cells. Anal Chem. 2006; 78: 2918-24.
    • (2006) Anal Chem , vol.78 , pp. 2918-2924
    • Herr, J.K.1
  • 34
    • 30044436689 scopus 로고    scopus 로고
    • A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165
    • Lee JH, et al. A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF165. Proc Natl Acad Sci USA. 2005; 102: 18902-7.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 18902-18907
    • Lee, J.H.1
  • 35
    • 0029379767 scopus 로고
    • Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor
    • Green LS, et al. Nuclease-resistant nucleic acid ligands to vascular permeability factor/vascular endothelial growth factor. Chem Biol. 1995; 2: 683-95.
    • (1995) Chem Biol , vol.2 , pp. 683-695
    • Green, L.S.1
  • 36
    • 11144239923 scopus 로고    scopus 로고
    • Pegaptanib for neovascular age-related mascular degeneration
    • Gragoudas ES, Adamis AP, Cunningham ET, et al. Pegaptanib for neovascular age-related mascular degeneration. N Engl J Med. 2004; 351: 2805-16.
    • (2004) N Engl J Med , vol.351 , pp. 2805-2816
    • Gragoudas, E.S.1    Adamis, A.P.2    Cunningham, E.T.3
  • 37
    • 0345827805 scopus 로고    scopus 로고
    • Technology evalution pegaptanib. Eyetech/Pfizer
    • Vinores SA. Technology evalution pegaptanib. Eyetech/Pfizer. Curr Opin Mol Ther. 2003; 5: 673-9.
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 673-679
    • Vinores, S.A.1
  • 38
    • 22744446011 scopus 로고    scopus 로고
    • Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration
    • Doggrell SA. Pegaptanib: the first antiangiogenic agent approved for neovascular macular degeneration. Expert Opin Pharmacother. 2005; 6: 1421-3.
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 1421-1423
    • Doggrell, S.A.1
  • 39
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW. In vitro selection of RNA molecules that bind specific ligands. Nature. 1990; 346: 818-22.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 40
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science. 1990; 249: 505-10.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 41
    • 79551561775 scopus 로고    scopus 로고
    • Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes
    • Taghdisi SM, Lavaee P, Ramezani M, Abnous K. Reversible targeting and controlled release delivery of daunorubicin to cancer cells by aptamer-wrapped carbon nanotubes. Eur J Pharm Biopharm. 2011; 77: 200-6.
    • (2011) Eur J Pharm Biopharm , vol.77 , pp. 200-206
    • Taghdisi, S.M.1    Lavaee, P.2    Ramezani, M.3    Abnous, K.4
  • 44
    • 0037344674 scopus 로고    scopus 로고
    • Toward third-generation aptamers: Spiegelmers and their therapeutic prospects
    • Vater A, Klussmann S. Toward third-generation aptamers: Spiegelmers and their therapeutic prospects. Curr Opin Drug Discov Dev. 2003; 6: 253-61.
    • (2003) Curr Opin Drug Discov Dev , vol.6 , pp. 253-261
    • Vater, A.1    Klussmann, S.2
  • 45
    • 0142043453 scopus 로고    scopus 로고
    • Spiegelmers: biostable aptamers Chem
    • Eulberg D, Klussmann S. Spiegelmers: biostable aptamers Chem. Biochem. 2003; 4: 979-83.
    • (2003) Biochem , vol.4 , pp. 979-983
    • Eulberg, D.1    Klussmann, S.2
  • 46
    • 10244257661 scopus 로고    scopus 로고
    • Application of locked nucleic acids to improve aptamer in vivo stability and targeting function
    • Schmidt KS, Borkowski S, Kurreck J, et al. Application of locked nucleic acids to improve aptamer in vivo stability and targeting function. Nucleic Acids Res. 2004; 32: 5757-65.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5757-5765
    • Schmidt, K.S.1    Borkowski, S.2    Kurreck, J.3
  • 47
    • 0032876515 scopus 로고    scopus 로고
    • Detection and plasma pharmacokinetics of an anto-vascular endothelial growth factor oligonucleotides-aptamer (NX1838) in rhesus monkeys
    • Tucker CE, Chen LS, Judkins MB, et al. Detection and plasma pharmacokinetics of an anto-vascular endothelial growth factor oligonucleotides-aptamer (NX1838) in rhesus monkeys. J Chromatogr B: Biomed Sci Appl. 1999; 732: 203-12.
    • (1999) J Chromatogr B: Biomed Sci Appl , vol.732 , pp. 203-212
    • Tucker, C.E.1    Chen, L.S.2    Judkins, M.B.3
  • 48
    • 84869020953 scopus 로고    scopus 로고
    • Aptamer-nanoparticle bioconjugates for drug delivery
    • In: Hashim AA, editor, doi: 10. 5772/35188
    • Ozalp VO and Schafer J. Aptamer-nanoparticle bioconjugates for drug delivery. In: Hashim AA, editor. The delivery of nanoparticles. 2012; doi: 10. 5772/35188.
    • (2012) The delivery of nanoparticles
    • Ozalp, V.O.1    Schafer, J.2
  • 49
    • 0036554863 scopus 로고    scopus 로고
    • Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery
    • Park JW, Hong K, Kirpotin DB, et al. Anti-HER2 immunoliposomes: enhanced efficacy attributable to targeted delivery. Clin Cancer Res. 2002; 8: 1172-81.
    • (2002) Clin Cancer Res , vol.8 , pp. 1172-1181
    • Park, J.W.1    Hong, K.2    Kirpotin, D.B.3
  • 50
    • 0033452416 scopus 로고    scopus 로고
    • Anti-HER2 immunoliposomes for targeted drug delivery
    • Hong K, Kirpotin DB, Park JW, et al. Anti-HER2 immunoliposomes for targeted drug delivery. Ann NY Acad Sci. 1999; 886: 293-6.
    • (1999) Ann NY Acad Sci , vol.886 , pp. 293-296
    • Hong, K.1    Kirpotin, D.B.2    Park, J.W.3
  • 51
    • 0034214039 scopus 로고    scopus 로고
    • Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo
    • de Menezes DE L, Pilarski LM, Belch AR, Allen TM. Selective targeting of immunoliposomal doxorubicin against human multiple myeloma in vitro and ex vivo. Biochim Biophys Acta. 2000; 1466: 205-20.
    • (2000) Biochim Biophys Acta , vol.1466 , pp. 205-220
    • de Menezes, D.E.L.1    Pilarski, L.M.2    Belch, A.R.3    Allen, T.M.4
  • 52
    • 0001160175 scopus 로고    scopus 로고
    • In vitro and in vivo targeting of immunoliposomal doxorubicin to human B cell Lymphoma
    • de Menezes DE L, Pilarski LM, Allen TM. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B cell Lymphoma. Cancer Res. 1998; 58: 3320-30.
    • (1998) Cancer Res , vol.58 , pp. 3320-3330
    • de Menezes, D.E.L.1    Pilarski, L.M.2    Allen, T.M.3
  • 53
    • 22644445076 scopus 로고    scopus 로고
    • Fahmy TM, Fong PM, Goyal A, Saltzman WM. Mater Today
    • Fahmy TM, Fong PM, Goyal A, Saltzman WM. Targeted for drug delivery. Mater Today. 2005; 5: 18-26.
    • (2005) Targeted for drug delivery , vol.5 , pp. 18-26
  • 54
    • 1642523582 scopus 로고    scopus 로고
    • Controlled drug release from hydrogel nanoparticle networks
    • Huang G, Gao J, Hu Z. Controlled drug release from hydrogel nanoparticle networks. J Control Release. 2004; 94: 303-11.
    • (2004) J Control Release , vol.94 , pp. 303-311
    • Huang, G.1    Gao, J.2    Hu, Z.3
  • 55
    • 0031989440 scopus 로고    scopus 로고
    • Surface modification of polyanhydride microspheres
    • Gao J, Niklason L, Zhao XM, Langer R. Surface modification of polyanhydride microspheres. J Pharm Sci. 1998; 87: 246-8.
    • (1998) J Pharm Sci , vol.87 , pp. 246-248
    • Gao, J.1    Niklason, L.2    Zhao, X.M.3    Langer, R.4
  • 56
    • 0033982176 scopus 로고    scopus 로고
    • Long term stability of PBCA nanoparticle suspensions
    • Sommerfeld P, Sabel BA, Schroeder U. Long term stability of PBCA nanoparticle suspensions. J Microencapsul. 2000; 17: 69-79.
    • (2000) J Microencapsul , vol.17 , pp. 69-79
    • Sommerfeld, P.1    Sabel, B.A.2    Schroeder, U.3
  • 57
    • 0032850436 scopus 로고    scopus 로고
    • A polycapro-lactone nanoparticle formulation of cyclosporine-A improves the prediction of area under the curve using a limited sampling strategy
    • Molpeceres J, Chacon M, Guzman M, et al. A polycapro-lactone nanoparticle formulation of cyclosporine-A improves the prediction of area under the curve using a limited sampling strategy. Int J Pharm. 1999; 187: 101-13.
    • (1999) Int J Pharm , vol.187 , pp. 101-113
    • Molpeceres, J.1    Chacon, M.2    Guzman, M.3
  • 58
    • 0028205133 scopus 로고
    • Biodegradable microspheres as controlled-release tetanus toxoid delivery systems
    • Alonso MJ, Gupta RK, Min C, et al. Biodegradable microspheres as controlled-release tetanus toxoid delivery systems. Vaccine. 1994; 12: 299-306.
    • (1994) Vaccine , vol.12 , pp. 299-306
    • Alonso, M.J.1    Gupta, R.K.2    Min, C.3
  • 59
    • 0037148662 scopus 로고    scopus 로고
    • Characterization of nanoparticle uptake by endothelial cells
    • Davda J, Labhasetwar V. Characterization of nanoparticle uptake by endothelial cells. Int J Pharm. 2002; 233: 51-9.
    • (2002) Int J Pharm , vol.233 , pp. 51-59
    • Davda, J.1    Labhasetwar, V.2
  • 60
    • 0037235331 scopus 로고    scopus 로고
    • In vitro characterization of poly orthoester microparticles containing bupivacaine
    • Deng JS, Li L, Tian Y, et al. In vitro characterization of poly orthoester microparticles containing bupivacaine. Pharm Dev Technol. 2003; 8: 31-8.
    • (2003) Pharm Dev Technol , vol.8 , pp. 31-38
    • Deng, J.S.1    Li, L.2    Tian, Y.3
  • 61
    • 0343247711 scopus 로고    scopus 로고
    • Biodegradation and biocompatibility of PLA and PLGA microspheres
    • Shive MS, Anderson JM. Biodegradation and biocompatibility of PLA and PLGA microspheres. Adv Drug Deliv Rev. 1997; 28: 5-24.
    • (1997) Adv Drug Deliv Rev , vol.28 , pp. 5-24
    • Shive, M.S.1    Anderson, J.M.2
  • 62
    • 0029120601 scopus 로고
    • Tissue reaction of bioabsorbable ultra high strength poly(L-lactide)rod. A long term study in rabbits
    • Matsusue Y, Hanafusa S, Yamamuro T, et al. Tissue reaction of bioabsorbable ultra high strength poly(L-lactide)rod. A long term study in rabbits. Clin Orthop Relat Res. 1995; 317: 246-53.
    • (1995) Clin Orthop Relat Res , vol.317 , pp. 246-253
    • Matsusue, Y.1    Hanafusa, S.2    Yamamuro, T.3
  • 63
    • 10044225776 scopus 로고    scopus 로고
    • Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs
    • Win KY, Feng SS. Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials. 2005; 26: 2713-22.
    • (2005) Biomaterials , vol.26 , pp. 2713-2722
    • Win, K.Y.1    Feng, S.S.2
  • 64
    • 79251579955 scopus 로고    scopus 로고
    • Surface functionalization of PLGA nanoparticles by non-covalent insertion of a homo-bifunctional spacer for active targeting in cancer therapy
    • Thamake SI, Raut SL, Ranjan AP, et al. Surface functionalization of PLGA nanoparticles by non-covalent insertion of a homo-bifunctional spacer for active targeting in cancer therapy. Nanotechnology. 2011; 22: 035101.
    • (2011) Nanotechnology , vol.22 , pp. 035101
    • Thamake, S.I.1    Raut, S.L.2    Ranjan, A.P.3
  • 65
    • 76749138904 scopus 로고    scopus 로고
    • The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells
    • Tong R, Yala L, Fan TM, Cheng J. The formulation of aptamer-coated paclitaxel-polylactide nanoconjugates and their targeting to cancer cells. Biomaterials. 2010; 31: 3043-53.
    • (2010) Biomaterials , vol.31 , pp. 3043-3053
    • Tong, R.1    Yala, L.2    Fan, T.M.3    Cheng, J.4
  • 67
    • 0032516078 scopus 로고    scopus 로고
    • Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment
    • Hobbs SK, Monsky WL, Yuan F, et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc Natl Acad Sci USA. 1998; 95: 4607-12.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 4607-4612
    • Hobbs, S.K.1    Monsky, W.L.2    Yuan, F.3
  • 68
    • 0033567094 scopus 로고    scopus 로고
    • Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor
    • Monsky WL, Fukumura D, Gohongi T, et al. Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor. Cancer Res. 1999; 59: 4129-35.
    • (1999) Cancer Res , vol.59 , pp. 4129-4135
    • Monsky, W.L.1    Fukumura, D.2    Gohongi, T.3
  • 69
    • 0029150245 scopus 로고
    • Vascular permeability in a human tumor xenograft: molecular size-dependence and cut-off size
    • Yuan F, Dellian M, Fukumura D, et al. Vascular permeability in a human tumor xenograft: molecular size-dependence and cut-off size. Cancer Res. 1995; 55: 3752-6.
    • (1995) Cancer Res , vol.55 , pp. 3752-3756
    • Yuan, F.1    Dellian, M.2    Fukumura, D.3
  • 70
    • 0041346051 scopus 로고    scopus 로고
    • Exploiting the hallmarks of cancer: the future conquest of breast cancer
    • Sledge Jr GW, Miller KD. Exploiting the hallmarks of cancer: the future conquest of breast cancer. Eur J Cancer. 2003; 39: 1668-75.
    • (2003) Eur J Cancer , vol.39 , pp. 1668-1675
    • Sledge Jr., G.W.1    Miller, K.D.2
  • 71
    • 0034176467 scopus 로고    scopus 로고
    • Molecular targets and cancer therapeutics: discovery, development and clinical validation
    • Teicher BA. Molecular targets and cancer therapeutics: discovery, development and clinical validation. Drug Resist Updat. 2000; 3: 67-73.
    • (2000) Drug Resist Updat , vol.3 , pp. 67-73
    • Teicher, B.A.1
  • 72
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
    • Maeda H, Wu J, Sawa T, et al. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J Control Release. 2000; 65: 271-84.
    • (2000) J Control Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3
  • 73
    • 0029379535 scopus 로고
    • Mechanisms of splenic clearance of blood cells and particles: towards development of new splenotropic agents
    • Moghimi SM. Mechanisms of splenic clearance of blood cells and particles: towards development of new splenotropic agents. Adv Drug Deliv Rev. 1995; 17: 103-15.
    • (1995) Adv Drug Deliv Rev , vol.17 , pp. 103-115
    • Moghimi, S.M.1
  • 74
    • 0026567096 scopus 로고
    • Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes
    • Liu D, Mori A, Huang L. Role of liposome size and RES blockade in controlling biodistribution and tumor uptake of GM1-containing liposomes. Biochim Biophys Acta. 1992; 1104: 95-101.
    • (1992) Biochim Biophys Acta , vol.1104 , pp. 95-101
    • Liu, D.1    Mori, A.2    Huang, L.3
  • 75
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrinand caveolae-mediated endocytosis
    • Rejman J, Oberle V, Zuhorn IS, et al. Size-dependent internalization of particles via the pathways of clathrinand caveolae-mediated endocytosis. Biochem J. 2004; 377: 159-69.
    • (2004) Biochem J , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3
  • 76
    • 0031815720 scopus 로고    scopus 로고
    • Size of IgG-opsonized particles determines macrophage response during internalization
    • Koval M, Prieter K, Adles C, et al. Size of IgG-opsonized particles determines macrophage response during internalization. Exp Cell Res. 1998; 242: 265-73.
    • (1998) Exp Cell Res , vol.242 , pp. 265-273
    • Koval, M.1    Prieter, K.2    Adles, C.3
  • 78
    • 33646582037 scopus 로고    scopus 로고
    • Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
    • Farokhzad OC, Cheng J, Teply BA, et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci USA. 2006; 103: 6315-20.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6315-6320
    • Farokhzad, O.C.1    Cheng, J.2    Teply, B.A.3
  • 79
    • 7444223607 scopus 로고    scopus 로고
    • Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells
    • Farokhzad OC, Jon S, Khademhosseini A, et al. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 2004; 64: 7668-72.
    • (2004) Cancer Res , vol.64 , pp. 7668-7672
    • Farokhzad, O.C.1    Jon, S.2    Khademhosseini, A.3
  • 80
    • 4444289982 scopus 로고    scopus 로고
    • Layer-by-layer surface modification and patterned electrodeposition of quantum dots
    • Jaffar S, Nam KT, Khademhosseini A, et al. Layer-by-layer surface modification and patterned electrodeposition of quantum dots. Nano Lett. 2004; 4: 1421-5.
    • (2004) Nano Lett , vol.4 , pp. 1421-1425
    • Jaffar, S.1    Nam, K.T.2    Khademhosseini, A.3
  • 81
    • 0036897324 scopus 로고    scopus 로고
    • Cationic charge determines the distribution of liposomes between the vascular and extra vascular compartments of tumors
    • Campbell RB, Fukumura D, Brown EB, et al. Cationic charge determines the distribution of liposomes between the vascular and extra vascular compartments of tumors. Cancer Res. 2002; 62: 6831-6.
    • (2002) Cancer Res , vol.62 , pp. 6831-6836
    • Campbell, R.B.1    Fukumura, D.2    Brown, E.B.3
  • 82
    • 0017317645 scopus 로고
    • Polymers for the sustained release of proteins and other macromolecules
    • Langer R, Folkman J. Polymers for the sustained release of proteins and other macromolecules. Nature. 1976; 263: 797-800.
    • (1976) Nature , vol.263 , pp. 797-800
    • Langer, R.1    Folkman, J.2
  • 83
    • 0030629959 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration, Pharm
    • Gref R, Minamitake Y, Peracchia MT, et al. Poly(ethylene glycol)-coated nanospheres: potential carriers for intravenous drug administration, Pharm. Biotechnol. 1997; 10: 167-98.
    • (1997) Biotechnol , vol.10 , pp. 167-198
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 85
    • 24044454384 scopus 로고    scopus 로고
    • Influence of polysaccharide coating on the interactions of nanoparticles with biological systems
    • Lemarchand C, Gref R, Passirani C, et al. Influence of polysaccharide coating on the interactions of nanoparticles with biological systems. Biomaterials. 2006; 27: 108-18.
    • (2006) Biomaterials , vol.27 , pp. 108-118
    • Lemarchand, C.1    Gref, R.2    Passirani, C.3
  • 86
    • 27944496941 scopus 로고    scopus 로고
    • Cell-specific targeting of nanoparticles by multivalent attachment of small molecules
    • Weissleder R, Kelly K, Sun EY, et al. Cell-specific targeting of nanoparticles by multivalent attachment of small molecules. Nat Biotechnol. 2005; 23: 1418-23.
    • (2005) Nat Biotechnol , vol.23 , pp. 1418-1423
    • Weissleder, R.1    Kelly, K.2    Sun, E.Y.3
  • 87
    • 0037681850 scopus 로고    scopus 로고
    • Pharmacokinetics of pegylated liposomal doxorubicin. Review of animal and human studies
    • Gabizon A, Shmeeda H, Barenholz Y. Pharmacokinetics of pegylated liposomal doxorubicin. Review of animal and human studies. Clin Pharmacokinet. 2003; 42: 419-36.
    • (2003) Clin Pharmacokinet , vol.42 , pp. 419-436
    • Gabizon, A.1    Shmeeda, H.2    Barenholz, Y.3
  • 88
    • 0034781649 scopus 로고    scopus 로고
    • Biodistribution of long-circulating PEG-grafted nanocapsules in mice:effects of PEG chain length and density
    • Mosqueira VC, Legrand P, Morgat JL, et al. Biodistribution of long-circulating PEG-grafted nanocapsules in mice: effects of PEG chain length and density. Pharm Res. 2001; 18: 1411-9.
    • (2001) Pharm Res , vol.18 , pp. 1411-1419
    • Mosqueira, V.C.1    Legrand, P.2    Morgat, J.L.3
  • 89
    • 23444444512 scopus 로고
    • Biodegradable long-circulating polymeric nanospheres
    • Gref R, Minamitake Y, Peracchia MT, et al. Biodegradable long-circulating polymeric nanospheres. Science. 1994; 263: 1600-3.
    • (1994) Science , vol.263 , pp. 1600-1603
    • Gref, R.1    Minamitake, Y.2    Peracchia, M.T.3
  • 90
    • 33750503424 scopus 로고    scopus 로고
    • Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
    • Cheng J, Teply BA, Sherifi I, et al. Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials. 2007; 28: 869-76.
    • (2007) Biomaterials , vol.28 , pp. 869-876
    • Cheng, J.1    Teply, B.A.2    Sherifi, I.3
  • 91
    • 0028281399 scopus 로고
    • A method for the high efficiency of water-soluble carbodiimide-mediated amidation
    • Sehgal D, Vijay IK. A method for the high efficiency of water-soluble carbodiimide-mediated amidation. Anal Biochem. 1994; 218: 87-91.
    • (1994) Anal Biochem , vol.218 , pp. 87-91
    • Sehgal, D.1    Vijay, I.K.2
  • 92
    • 84862980867 scopus 로고    scopus 로고
    • Aptamer-labeled PLGA nanoparticles for targeting cancer cells
    • doi 10. 1007/s12645-011-0024-6
    • Aravind A, Varghese SH, Veeranarayanan S, et al. Aptamer-labeled PLGA nanoparticles for targeting cancer cells. Cancer Nano. 2012. doi 10. 1007/s12645-011-0024-6.
    • (2012) Cancer Nano
    • Aravind, A.1    Varghese, S.H.2    Veeranarayanan, S.3
  • 93
    • 77958542009 scopus 로고    scopus 로고
    • Aptamer conjugated magnetic nanoparticles as nanosurgeons
    • Nair BG, Nagaoka Y, Morimoto H, et al. Aptamer conjugated magnetic nanoparticles as nanosurgeons. Nanotechnology. 2010; 21: 455102-10.
    • (2010) Nanotechnology , vol.21 , pp. 455102-455110
    • Nair, B.G.1    Nagaoka, Y.2    Morimoto, H.3
  • 94
    • 66449095059 scopus 로고    scopus 로고
    • Current advances in research and clinical applications of PLGA-based nanotechnology
    • Lü J, Wang X, Marin-Muller C, Wang H, Lin PH, Yao Q, et al. Current advances in research and clinical applications of PLGA-based nanotechnology. Expert Rev Mol Diagn. 2009; 9: 325-41.
    • (2009) Expert Rev Mol Diagn , vol.9 , pp. 325-341
    • Lü, J.1    Wang, X.2    Marin-Muller, C.3    Wang, H.4    Lin, P.H.5    Yao, Q.6
  • 95
    • 85047696587 scopus 로고    scopus 로고
    • A simple synthetic route to the formation of a block copolymer of poly (lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applications
    • Lavik EB, Hrkach JS, Lotan N, et al. A simple synthetic route to the formation of a block copolymer of poly (lactic-co-glycolic acid) and polylysine for the fabrication of functionalized, degradable structures for biomedical applications. J Biomed Mater Res. 2001; 58: 291-4.
    • (2001) J Biomed Mater Res , vol.58 , pp. 291-294
    • Lavik, E.B.1    Hrkach, J.S.2    Lotan, N.3
  • 96
    • 0032957322 scopus 로고    scopus 로고
    • Microparticles of novel branched copolymers of lactic acid and amino acids: preparation and characterization
    • Caponetti G, Hrkach JS, Kriwet B, et al. Microparticles of novel branched copolymers of lactic acid and amino acids: preparation and characterization. J Pharm Sci. 1999; 88: 136-41.
    • (1999) J Pharm Sci , vol.88 , pp. 136-141
    • Caponetti, G.1    Hrkach, J.S.2    Kriwet, B.3
  • 97
    • 0037331755 scopus 로고    scopus 로고
    • Ligand-specific targeting of microspheres to phagocytes by surface modification withpoly(L-lysine)-grafted poly(ethylene glycol) conjugate
    • Faraasen S, Voros J, Csucs G, et al. Ligand-specific targeting of microspheres to phagocytes by surface modification withpoly(L-lysine)-grafted poly(ethylene glycol) conjugate. Pharm Res. 2003; 20: 237-46.
    • (2003) Pharm Res , vol.20 , pp. 237-246
    • Faraasen, S.1    Voros, J.2    Csucs, G.3
  • 98
    • 0033166980 scopus 로고    scopus 로고
    • Production of microspheres with surface amino groups from blends of poly(lactide-co-glycolide) and poly(epsilon-CBZ-L-lysine) and use for encapsulation
    • Zheng J, Hornsby PJ. Production of microspheres with surface amino groups from blends of poly(lactide-co-glycolide) and poly(epsilon-CBZ-L-lysine) and use for encapsulation. Biotechnol Program. 1999; 15: 763-7.
    • (1999) Biotechnol Program , vol.15 , pp. 763-767
    • Zheng, J.1    Hornsby, P.J.2
  • 99
    • 11444269911 scopus 로고    scopus 로고
    • Biodegradable microspheres with enhanced capacity for covalently bound surface ligands
    • Keegan ME, Falcone JL, Leung TC, et al. Biodegradable microspheres with enhanced capacity for covalently bound surface ligands. Macromolecules. 2004; 37: 9779-984.
    • (2004) Macromolecules , vol.37 , pp. 9779-9984
    • Keegan, M.E.1    Falcone, J.L.2    Leung, T.C.3
  • 100
  • 101
    • 0031984289 scopus 로고    scopus 로고
    • Integration of surface modification and 3D fabrication techniques to prepare patterned poly (l-lactide) substrates allowing regionally selective cell adhesion
    • Park A, Wu B, Griffith LG. Integration of surface modification and 3D fabrication techniques to prepare patterned poly (l-lactide) substrates allowing regionally selective cell adhesion. J Biomater Sci Polym Ed. 1998; 9: 89-110.
    • (1998) J Biomater Sci Polym Ed , vol.9 , pp. 89-110
    • Park, A.1    Wu, B.2    Griffith, L.G.3
  • 102
    • 1642566537 scopus 로고    scopus 로고
    • Controllable surface modification of poly(lactic-co-glycolic acid) (PLGA) by hydrolysis or aminolysis I: physical, chemical, and theoretical aspects
    • Croll TI, O'Connor AJ, Stevens GW, et al. Controllable surface modification of poly(lactic-co-glycolic acid) (PLGA) by hydrolysis or aminolysis I: physical, chemical, and theoretical aspects. Biomacromolecules. 2004; 5: 463-73.
    • (2004) Biomacromolecules , vol.5 , pp. 463-473
    • Croll, T.I.1    O'Connor, A.J.2    Stevens, G.W.3
  • 103
    • 1542399116 scopus 로고    scopus 로고
    • Production and surface modification of polylactide-based polymeric scaffolds for soft-tissue engineering
    • Cao Y, Croll TI, Cooper-White J, et al. Production and surface modification of polylactide-based polymeric scaffolds for soft-tissue engineering. Methods Mol Biol. 2004; 238: 87-112.
    • (2004) Methods Mol Biol , vol.238 , pp. 87-112
    • Cao, Y.1    Croll, T.I.2    Cooper-White, J.3
  • 104
    • 0348014771 scopus 로고    scopus 로고
    • Plasma-treated, collagen anchored polylactone: its cell affinity evaluation under shear or shear-free conditions J
    • Yang J, Wan Y, Yang J, et al. Plasma-treated, collagen anchored polylactone: its cell affinity evaluation under shear or shear-free conditions J. Biomed Mater Res. 2003; 67A: 1139-47.
    • (2003) Biomed Mater Res , vol.67 A , pp. 1139-1147
    • Yang, J.1    Wan, Y.2    Yang, J.3
  • 105
    • 2342433916 scopus 로고    scopus 로고
    • Characterization of surface property of poly(lactide-co-glycolide) after oxygen plasma treatment
    • Wan YQ, Qu X, Bei JZ, et al. Characterization of surface property of poly(lactide-co-glycolide) after oxygen plasma treatment. Biomaterials. 2004; 25: 4777-83.
    • (2004) Biomaterials , vol.25 , pp. 4777-4783
    • Wan, Y.Q.1    Qu, X.2    Bei, J.Z.3
  • 106
    • 77958152852 scopus 로고    scopus 로고
    • Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals
    • Orava EW, Cicmil N, Gariépy J. Delivering cargoes into cancer cells using DNA aptamers targeting internalized surface portals. Biochim Biophys Acta. 2010; 1798: 2190-200.
    • (2010) Biochim Biophys Acta , vol.1798 , pp. 2190-2200
    • Orava, E.W.1    Cicmil, N.2    Gariépy, J.3
  • 107
    • 33845723241 scopus 로고    scopus 로고
    • An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform
    • Bagalkot V, Farokhzad OC, Langer R, Jon S. An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem. 2006; 45: 8149-52.
    • (2006) Angew Chem , vol.45 , pp. 8149-8152
    • Bagalkot, V.1    Farokhzad, O.C.2    Langer, R.3    Jon, S.4
  • 108
    • 63349112005 scopus 로고    scopus 로고
    • Phototoxic aptamers selectively enter and kill epithelial cancer cells
    • Ferreira CS, Cheung MC, Missailidis S, et al. Phototoxic aptamers selectively enter and kill epithelial cancer cells. Nucleic Acids Res. 2009; 37: 866-76.
    • (2009) Nucleic Acids Res , vol.37 , pp. 866-876
    • Ferreira, C.S.1    Cheung, M.C.2    Missailidis, S.3
  • 109
    • 65549102827 scopus 로고    scopus 로고
    • Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells
    • Huang YF, Shangguan D, Liu H, et al. Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells. Chembiochem. 2009; 10: 862-8.
    • (2009) Chembiochem , vol.10 , pp. 862-868
    • Huang, Y.F.1    Shangguan, D.2    Liu, H.3
  • 110
    • 0027134326 scopus 로고
    • (6-Maleimidocaproyl)hydrazone of doxorubicin-a new derivative for the preparation of immunoconjugates of doxorubicin
    • Willner D, Trail PA, Hofstead SJ, et al. (6-Maleimidocaproyl)hydrazone of doxorubicin-a new derivative for the preparation of immunoconjugates of doxorubicin. Bioconjug Chem. 1993; 4: 521-7.
    • (1993) Bioconjug Chem , vol.4 , pp. 521-527
    • Willner, D.1    Trail, P.A.2    Hofstead, S.J.3
  • 111
    • 33745714275 scopus 로고    scopus 로고
    • Aptamer: toxin conjugates that specifically target prostate tumor cells
    • Chu TC, Marks III JW, Lavery LA, et al. Aptamer: toxin conjugates that specifically target prostate tumor cells. Cancer Res. 2006; 66: 5989-92.
    • (2006) Cancer Res , vol.66 , pp. 5989-5992
    • Chu, T.C.1    Marks, J.W.2    Lavery, L.A.3
  • 112
    • 0038167143 scopus 로고    scopus 로고
    • Aptamer-based biosensor arrays for detection and quantification of biological macromolecules
    • McCauley TG, Hamaguchi N, Stanton M. Aptamer-based biosensor arrays for detection and quantification of biological macromolecules. Anal Biochem. 2003; 319: 244-50.
    • (2003) Anal Biochem , vol.319 , pp. 244-250
    • McCauley, T.G.1    Hamaguchi, N.2    Stanton, M.3
  • 114
    • 77954362096 scopus 로고    scopus 로고
    • Aptamer-targeted cell-specific RNA interference
    • Zhou J, Rossi JJ. Aptamer-targeted cell-specific RNA interference. Silence. 2010; 1: 4.
    • (2010) Silence , vol.1 , pp. 4
    • Zhou, J.1    Rossi, J.J.2
  • 115
    • 33645238918 scopus 로고    scopus 로고
    • Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates
    • Chu TC, et al. Labeling tumor cells with fluorescent nanocrystal-aptamer bioconjugates. Biosens Bioelectron. 2006; 21: 1859-66.
    • (2006) Biosens Bioelectron , vol.21 , pp. 1859-1866
    • Chu, T.C.1
  • 116
    • 33747031960 scopus 로고    scopus 로고
    • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
    • McNamara JO, et al. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat Biotechnol. 2006; 24: 1005-15.
    • (2006) Nat Biotechnol , vol.24 , pp. 1005-1015
    • McNamara, J.O.1
  • 117
    • 24644523302 scopus 로고    scopus 로고
    • Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors
    • Huang CC, et al. Aptamer-modified gold nanoparticles for colorimetric determination of platelet-derived growth factors and their receptors. Anal Chem. 2005; 77: 5735-41.
    • (2005) Anal Chem , vol.77 , pp. 5735-5741
    • Huang, C.C.1
  • 118
    • 80054972865 scopus 로고    scopus 로고
    • Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging
    • Chen T, Shukoor MI, Wang R, Zhao Z, Yuan Q, Bamrungsap S, et al. Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging. ACS Nano. 2011; 5(10): 7866-73.
    • (2011) ACS Nano , vol.5 , Issue.10 , pp. 7866-7873
    • Chen, T.1    Shukoor, M.I.2    Wang, R.3    Zhao, Z.4    Yuan, Q.5    Bamrungsap, S.6
  • 119
    • 0032170107 scopus 로고    scopus 로고
    • Liposome-anchored vascular endothelial growth factor aptamers
    • Willis MC, et al. Liposome-anchored vascular endothelial growth factor aptamers. Bioconjug Chem. 1998; 9: 573-82.
    • (1998) Bioconjug Chem , vol.9 , pp. 573-582
    • Willis, M.C.1
  • 122
    • 36248973801 scopus 로고    scopus 로고
    • Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer
    • Bagalkot V, et al. Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett. 2007; 7: 3065-70.
    • (2007) Nano Lett , vol.7 , pp. 3065-3070
    • Bagalkot, V.1
  • 123
    • 33846185936 scopus 로고    scopus 로고
    • Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors
    • Maehashi K, et al. Label-free protein biosensor based on aptamer-modified carbon nanotube field-effect transistors. Anal Chem. 2007; 79: 782-7.
    • (2007) Anal Chem , vol.79 , pp. 782-787
    • Maehashi, K.1
  • 124
    • 84857704148 scopus 로고    scopus 로고
    • Multifunctional plasmonic shell-magnetic core nanoparticles for targeted diagnostics, isolation, and photothermal destruction of tumor cells
    • doi: 10. 1021/nn2045246
    • Fan Z, Shelton M, Singh AK, et al. Multifunctional plasmonic shell-magnetic core nanoparticles for targeted diagnostics, isolation, and photothermal destruction of tumor cells. ACS Nano. 2012; 6: 1065-73. doi: 10. 1021/nn2045246.
    • (2012) ACS Nano , vol.6 , pp. 1065-1073
    • Fan, Z.1    Shelton, M.2    Singh, A.K.3
  • 125
    • 70349917999 scopus 로고    scopus 로고
    • Peptide- and aptamer- functionalized nanovectors for targeted delivery of therapeutics
    • Pangburn TO, Petersen MA, Waybrant B, et al. Peptide- and aptamer- functionalized nanovectors for targeted delivery of therapeutics. J Biomech Eng. 2009; 131: 0740051-07400520.
    • (2009) J Biomech Eng , vol.131 , pp. 0740051-07400520
    • Pangburn, T.O.1    Petersen, M.A.2    Waybrant, B.3
  • 127
    • 0032400798 scopus 로고    scopus 로고
    • Current evaluation of the tissue localization and diagnostic utility of prostate specific membrane antigen
    • Murphy GP, Elgamal AA, Su SL, et al. Current evaluation of the tissue localization and diagnostic utility of prostate specific membrane antigen. Cancer. 1998; 83: 2259-69.
    • (1998) Cancer , vol.83 , pp. 2259-2269
    • Murphy, G.P.1    Elgamal, A.A.2    Su, S.L.3
  • 128
    • 24644502180 scopus 로고    scopus 로고
    • Microfluidic system for studying the interaction of nanoparticles and microparticles with cells
    • Farokhzad OC, Khademhosseini A, Jon S, et al. Microfluidic system for studying the interaction of nanoparticles and microparticles with cells. Anal Chem. 2005; 77: 5453-9.
    • (2005) Anal Chem , vol.77 , pp. 5453-5459
    • Farokhzad, O.C.1    Khademhosseini, A.2    Jon, S.3
  • 129
    • 77956926324 scopus 로고    scopus 로고
    • Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications
    • Tong R, Coyle VJ, Tang L, et al. Polylactide nanoparticles containing stably incorporated cyanine dyes for in vitro and in vivo imaging applications. Micro Res Technol. 2010; 73: 901-9.
    • (2010) Micro Res Technol , vol.73 , pp. 901-909
    • Tong, R.1    Coyle, V.J.2    Tang, L.3
  • 130
    • 3042773832 scopus 로고    scopus 로고
    • Combination of local, nonviral IL12 gene therapy and systemic paclitaxel treatment in a metastatic breast cancer model
    • Janat-Amsbury MM, Yockman JW, Lee M, Kern S, Furgeson DY, Bikram M, et al. Combination of local, nonviral IL12 gene therapy and systemic paclitaxel treatment in a metastatic breast cancer model. Mol Ther. 2004; 9: 829-36.
    • (2004) Mol Ther , vol.9 , pp. 829-836
    • Janat-Amsbury, M.M.1    Yockman, J.W.2    Lee, M.3    Kern, S.4    Furgeson, D.Y.5    Bikram, M.6
  • 132
    • 67649764432 scopus 로고    scopus 로고
    • siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells
    • Dong X, Liu A, Zer C, Feng J, Zhen Z, Yang M, et al. siRNA inhibition of telomerase enhances the anti-cancer effect of doxorubicin in breast cancer cells. BMC Cancer. 2009; 9: 133-42.
    • (2009) BMC Cancer , vol.9 , pp. 133-142
    • Dong, X.1    Liu, A.2    Zer, C.3    Feng, J.4    Zhen, Z.5    Yang, M.6
  • 133
    • 77950051368 scopus 로고    scopus 로고
    • Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex
    • Kim E, Jung Y, Choi H, et al. Prostate cancer cell death produced by the co-delivery of Bcl-xL shRNA and doxorubicin using an aptamer-conjugated polyplex. Biomaterials. 2010; 31: 4592-9.
    • (2010) Biomaterials , vol.31 , pp. 4592-4599
    • Kim, E.1    Jung, Y.2    Choi, H.3
  • 134
    • 56249097260 scopus 로고    scopus 로고
    • Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles
    • Dhar S, Gu FX, Langer R, et al. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc Natl Acad Sci USA. 2008; 105: 17356-61.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 17356-17361
    • Dhar, S.1    Gu, F.X.2    Langer, R.3
  • 135
    • 79952165883 scopus 로고    scopus 로고
    • Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo
    • doi: 10. 1073/pnas. 1011379108
    • Dhar S, Kolishetti N, Lippard SJ and Farokhzad OC. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc Natl Acad Sci USA 2012. doi: 10. 1073/pnas. 1011379108.
    • (2012) Proc Natl Acad Sci USA
    • Dhar, S.1    Kolishetti, N.2    Lippard, S.J.3    Farokhzad, O.C.4
  • 136
    • 80054741757 scopus 로고    scopus 로고
    • Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation
    • Shi J, Xiao Z, Kamaly N, Farokhzad OC. Self-assembled targeted nanoparticles: evolution of technologies and bench to bedside translation. Acc Chem Res. 2011; 44: 1123-34.
    • (2011) Acc Chem Res , vol.44 , pp. 1123-1134
    • Shi, J.1    Xiao, Z.2    Kamaly, N.3    Farokhzad, O.C.4
  • 137
    • 79952485687 scopus 로고    scopus 로고
    • Nanotechnology-based cancer therapeutics-promise and challenge-lessons learned through the NCI alliance for nanotechnology in cancer
    • Farrell D, Ptak K, Nicholas J, et al. Nanotechnology-based cancer therapeutics-promise and challenge-lessons learned through the NCI alliance for nanotechnology in cancer. Pharm Res. 2011; 28: 273-8.
    • (2011) Pharm Res , vol.28 , pp. 273-278
    • Farrell, D.1    Ptak, K.2    Nicholas, J.3
  • 138
    • 40649105534 scopus 로고    scopus 로고
    • Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers
    • Gu F, Zhang L, Teply BA, et al. Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci USA. 2008; 105: 2586-91.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 2586-2591
    • Gu, F.1    Zhang, L.2    Teply, B.A.3
  • 139
    • 0038064320 scopus 로고    scopus 로고
    • Cisplatin incorporated in microspheres: development and fundamental studies for its clinical application
    • Fujiyama J, Nakase Y, Osaki K, et al. Cisplatin incorporated in microspheres: development and fundamental studies for its clinical application. J Control Release. 2003; 89: 397-408.
    • (2003) J Control Release , vol.89 , pp. 397-408
    • Fujiyama, J.1    Nakase, Y.2    Osaki, K.3
  • 140
    • 0037133087 scopus 로고    scopus 로고
    • PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties
    • Avgoustakis K, Beletsi A, Panagi Z, et al. PLGA-mPEG nanoparticles of cisplatin: in vitro nanoparticle degradation, in vitro drug release and in vivo drug residence in blood properties. J Control Release. 2002; 79: 123-35.
    • (2002) J Control Release , vol.79 , pp. 123-135
    • Avgoustakis, K.1    Beletsi, A.2    Panagi, Z.3
  • 141
    • 0038699633 scopus 로고    scopus 로고
    • Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles
    • Avgoustakis K, Beletsi A, Panagi Z, et al. Effect of copolymer composition on the physicochemical characteristics, in vitro stability, and biodistribution of PLGA-mPEG nanoparticles. Int J Pharm. 2003; 259: 115-27.
    • (2003) Int J Pharm , vol.259 , pp. 115-127
    • Avgoustakis, K.1    Beletsi, A.2    Panagi, Z.3
  • 142
    • 0035187843 scopus 로고    scopus 로고
    • Polylactide-poly(ethylene glycol) micellar-like particles as potential drug carriers: production, colloidal properties and biological performance
    • Stolnik S, et al. Polylactide-poly(ethylene glycol) micellar-like particles as potential drug carriers: production, colloidal properties and biological performance. J Drug Target. 2001; 9: 361-78.
    • (2001) J Drug Target , vol.9 , pp. 361-378
    • Stolnik, S.1
  • 143
    • 39849111660 scopus 로고    scopus 로고
    • Characterization of cisplatin cytotoxicity delivered from PLGA-systems
    • Moreno D, et al. Characterization of cisplatin cytotoxicity delivered from PLGA-systems. Eur J Pharm Biopharm. 2008; 68: 503-12.
    • (2008) Eur J Pharm Biopharm , vol.68 , pp. 503-512
    • Moreno, D.1
  • 145
    • 78149260773 scopus 로고    scopus 로고
    • Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy
    • Kolishetti N, Dhar S, Valencia PM, et al. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci USA. 2010; 107: 17939-44.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 17939-17944
    • Kolishetti, N.1    Dhar, S.2    Valencia, P.M.3
  • 146
    • 80051817418 scopus 로고    scopus 로고
    • Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery
    • Guo J, Gao X, Su L, et al. Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug delivery. Biomaterials. 2011; 32: 8010-20.
    • (2011) Biomaterials , vol.32 , pp. 8010-8020
    • Guo, J.1    Gao, X.2    Su, L.3
  • 147
    • 58249086971 scopus 로고    scopus 로고
    • PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery
    • Chan JM, Zhang L, Yuet KP, et al. PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery. Biomaterials. 2009; 30: 1627-34.
    • (2009) Biomaterials , vol.30 , pp. 1627-1634
    • Chan, J.M.1    Zhang, L.2    Yuet, K.P.3
  • 148
    • 77951223396 scopus 로고    scopus 로고
    • ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation
    • Wang AZ, Yuet K, Zhang LF, et al. ChemoRad nanoparticles: a novel multifunctional nanoparticle platform for targeted delivery of concurrent chemoradiation. Nanomedicine. 2010; 5: 361-8.
    • (2010) Nanomedicine , vol.5 , pp. 361-368
    • Wang, A.Z.1    Yuet, K.2    Zhang, L.F.3
  • 149
    • 84856153806 scopus 로고    scopus 로고
    • Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection
    • Xiao Z, Levy-Nissenbaum E, Alexis F, et al. Engineering of targeted nanoparticles for cancer therapy using internalizing aptamers isolated by cell-uptake selection. ACS Nano. 2012; 6: 696-704.
    • (2012) ACS Nano , vol.6 , pp. 696-704
    • Xiao, Z.1    Levy-Nissenbaum, E.2    Alexis, F.3
  • 150
    • 33750445311 scopus 로고    scopus 로고
    • DNA aptamers that bind to MUC1 tumour marker: design and characterization of MUC1-binding single-stranded DNA aptamers
    • Ferreira CS, et al. DNA aptamers that bind to MUC1 tumour marker: design and characterization of MUC1-binding single-stranded DNA aptamers. Tumour Biol. 2006; 27: 289-301.
    • (2006) Tumour Biol , vol.27 , pp. 289-301
    • Ferreira, C.S.1
  • 151
    • 80052349603 scopus 로고    scopus 로고
    • Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro
    • Yu C, Hu Y, Duan J, et al. Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro. PLoS One. 2011; 6: e24077.
    • (2011) PLoS One , vol.6
    • Yu, C.1    Hu, Y.2    Duan, J.3
  • 152
    • 0026747885 scopus 로고
    • Early intervention in cancer using monoclonal antibodies and other biological ligands: micropharmacology and the binding site barrier
    • Weinstein JN, van Osdol W. Early intervention in cancer using monoclonal antibodies and other biological ligands: micropharmacology and the "binding site barrier". Cancer Res. 1992; 52: 2747-51.
    • (1992) Cancer Res , vol.52 , pp. 2747-2751
    • Weinstein, J.N.1    van Osdol, W.2
  • 153
    • 0035816177 scopus 로고    scopus 로고
    • Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function
    • Jain RK. Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. J Control Release. 2001; 74: 7-25.
    • (2001) J Control Release , vol.74 , pp. 7-25
    • Jain, R.K.1
  • 154
    • 0034648765 scopus 로고    scopus 로고
    • Angiogenesis in cancer and other diseases
    • Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature. 2000; 407: 249-57.
    • (2000) Nature , vol.407 , pp. 249-257
    • Carmeliet, P.1    Jain, R.K.2
  • 155
    • 0026089377 scopus 로고
    • Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions
    • Less JR, Skalak TC, Sevick EMC, Jain RK. Microvascular architecture in a mammary carcinoma: branching patterns and vessel dimensions. Cancer Res. 1991; 51: 265-73.
    • (1991) Cancer Res , vol.51 , pp. 265-273
    • Less, J.R.1    Skalak, T.C.2    Sevick, E.M.C.3    Jain, R.K.4
  • 156
    • 0029986979 scopus 로고    scopus 로고
    • Intussusceptive microvascular growth in solid tumors: a novel mechanism of tumorangiogenesis
    • Patan S, Munn LL, Jain RK. Intussusceptive microvascular growth in solid tumors: a novel mechanism of tumorangiogenesis. Microvasc Res. 1996; 51: 260-72.
    • (1996) Microvasc Res , vol.51 , pp. 260-272
    • Patan, S.1    Munn, L.L.2    Jain, R.K.3
  • 157
    • 0001123485 scopus 로고    scopus 로고
    • Tumor angiogenesis
    • 5th edn., J. F. Holland, E. FreiIII, R. C. BastJr, D. W. Kufe, R. E. Pollock, and R. R. Weichselbaum (Eds.), Ontario: Decker
    • Folkman J. Tumor angiogenesis. In: Holland JF, Frei III E, Bast Jr RC, Kufe DW, Pollock RE, Weichselbaum RR, editors. Cancer medicine. 5th ed. Ontario: Decker; 2000. p. 132-52.
    • (2000) Cancer Medicine , pp. 132-152
    • Folkman, J.1
  • 159
    • 0023909330 scopus 로고
    • Determinants of tumor blood flow: a review
    • Jain RK. Determinants of tumor blood flow: a review. Cancer Res. 1988; 48: 2641-58.
    • (1988) Cancer Res , vol.48 , pp. 2641-2658
    • Jain, R.K.1
  • 160
    • 0023219734 scopus 로고
    • Transport of molecules in the tumor interstitium: a review
    • Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res. 1987; 47: 3039-51.
    • (1987) Cancer Res , vol.47 , pp. 3039-3051
    • Jain, R.K.1
  • 161
    • 0033799839 scopus 로고    scopus 로고
    • Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs
    • Krishna R, Mayer LD. Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci. 2000; 11: 265-83.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 265-283
    • Krishna, R.1    Mayer, L.D.2
  • 162
    • 27744539110 scopus 로고    scopus 로고
    • Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival
    • Mi J, Zhang X, Giangrande PH, et al. Targeted inhibition of alphavbeta3 integrin with an RNA aptamer impairs endothelial cell growth and survival. Biochem Biophys Res Commun. 2005; 338: 956-63.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 956-963
    • Mi, J.1    Zhang, X.2    Giangrande, P.H.3
  • 163
    • 0041923790 scopus 로고    scopus 로고
    • Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3
    • Chen CH, Chernis GA, Hoang VQ, Landgraf R. Inhibition of heregulin signaling by an aptamer that preferentially binds to the oligomeric form of human epidermal growth factor receptor-3. Proc Natl Acad Sci USA. 2003; 100: 9226-31.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9226-9231
    • Chen, C.H.1    Chernis, G.A.2    Hoang, V.Q.3    Landgraf, R.4
  • 164
    • 0037099536 scopus 로고    scopus 로고
    • Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
    • Lupold SE, et al. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. 2002; 62: 4029-33.
    • (2002) Cancer Res , vol.62 , pp. 4029-4033
    • Lupold, S.E.1
  • 165
    • 0038476179 scopus 로고    scopus 로고
    • Biophysical and biological properties of quadruplex oligonucleotides
    • Dapic V, Abdomerovic V, Marrington R, et al. Biophysical and biological properties of quadruplex oligonucleotides. Nucleic Acids Res. 2003; 31: 2097-107.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2097-2107
    • Dapic, V.1    Abdomerovic, V.2    Marrington, R.3
  • 168
    • 0034814741 scopus 로고    scopus 로고
    • In vitro selection of the RNA aptamer against Sialyl Lewis X and its inhibition of the cell adhesion
    • Jeong S, Eom T, Kim S, et al. In vitro selection of the RNA aptamer against Sialyl Lewis X and its inhibition of the cell adhesion. Biochem Biophys Res Commun. 2001; 281: 237-43.
    • (2001) Biochem Biophys Res Commun , vol.281 , pp. 237-243
    • Jeong, S.1    Eom, T.2    Kim, S.3
  • 169
    • 0242610799 scopus 로고    scopus 로고
    • Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity
    • Santulli-Marotto S, Nair SK, Rusconi C, et al. Multivalent RNA aptamers that inhibit CTLA-4 and enhance tumor immunity. Cancer Res. 2003; 63: 7483-9.
    • (2003) Cancer Res , vol.63 , pp. 7483-7489
    • Santulli-Marotto, S.1    Nair, S.K.2    Rusconi, C.3
  • 170
    • 33747053632 scopus 로고    scopus 로고
    • Aptamers evolved from live cells as effective molecular probes for cancer study
    • Shangguan D, et al. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci USA. 2006; 103: 11838-43.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11838-11843
    • Shangguan, D.1
  • 171
    • 46049108242 scopus 로고    scopus 로고
    • Cell-specific internalization study of an aptamer from whole cell selection
    • Xiao Z, et al. Cell-specific internalization study of an aptamer from whole cell selection. Chemistry. 2008; 14: 1769-75.
    • (2008) Chemistry , vol.14 , pp. 1769-1775
    • Xiao, Z.1
  • 172
    • 0347364648 scopus 로고    scopus 로고
    • A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment
    • Daniels DA, et al. A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc Natl Acad Sci USA. 2003; 100: 15416-21.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 15416-15421
    • Daniels, D.A.1
  • 173
    • 0035966106 scopus 로고    scopus 로고
    • Tenascin-C aptamers are generated using tumor cells and purified protein
    • Hicke BJ, Marion C, Chang YF, et al. Tenascin-C aptamers are generated using tumor cells and purified protein. J Biol Chem. 2001; 276: 48644-54.
    • (2001) J Biol Chem , vol.276 , pp. 48644-48654
    • Hicke, B.J.1    Marion, C.2    Chang, Y.F.3
  • 174
    • 0035844150 scopus 로고    scopus 로고
    • Systemic evolution of a DNA aptamer binding to rat brain tumor microvessels, selective targeting of endothelial regulatory protein pigpen
    • Blank M, Weinschenk T, Priemer M, et al. Systemic evolution of a DNA aptamer binding to rat brain tumor microvessels, selective targeting of endothelial regulatory protein pigpen. J Biol Chem. 2001; 276: 16464-8.
    • (2001) J Biol Chem , vol.276 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3
  • 175
    • 0029806701 scopus 로고    scopus 로고
    • Inhibitory DNA ligands to platelet-derived growth factor B-chain
    • Green LS, et al. Inhibitory DNA ligands to platelet-derived growth factor B-chain. Biochemistry. 1996; 35: 14413-24.
    • (1996) Biochemistry , vol.35 , pp. 14413-14424
    • Green, L.S.1
  • 176
    • 33644676039 scopus 로고    scopus 로고
    • Detection of oncoprotein platelet-derived growth factor using a fluorescent signaling complex of an aptamer and TOTO
    • Zhou C, et al. Detection of oncoprotein platelet-derived growth factor using a fluorescent signaling complex of an aptamer and TOTO. Anal Bioanal Chem. 2006; 384: 1175-80.
    • (2006) Anal Bioanal Chem , vol.384 , pp. 1175-1180
    • Zhou, C.1
  • 177
    • 19944428130 scopus 로고    scopus 로고
    • Direct in vitro selection of a 2′-O-methyl aptamer to VEGF
    • Burmeister P, et al. Direct in vitro selection of a 2′-O-methyl aptamer to VEGF. Chem Biol. 2005; 12: 25-33.
    • (2005) Chem Biol , vol.12 , pp. 25-33
    • Burmeister, P.1
  • 178
    • 0032493654 scopus 로고    scopus 로고
    • 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
    • Ruckman J, et al. 2′-Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J Biol Chem. 1998; 273: 20556-67.
    • (1998) J Biol Chem , vol.273 , pp. 20556-20567
    • Ruckman, J.1
  • 179
    • 18344375927 scopus 로고    scopus 로고
    • Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase
    • Cerchia L, et al. Neutralizing aptamers from whole-cell SELEX inhibit the RET receptor tyrosine kinase. PLoS Biol. 2005; 3: e123.
    • (2005) PLoS Biol , vol.3
    • Cerchia, L.1
  • 180
    • 34247389227 scopus 로고    scopus 로고
    • Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma
    • Pashenkov M, et al. Phase II trial of a toll-like receptor 9-activating oligonucleotide in patients with metastatic melanoma. J Clin Oncol. 2006; 24: 5716-24.
    • (2006) J Clin Oncol , vol.24 , pp. 5716-5724
    • Pashenkov, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.