2'-fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165): Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain

Journal of Biological Chemistry

Volumn 273, Issue 32, 1998, Pages 20556-20567

  Ruckman, Judy ^a   Green, Louis S ^a   Beeson, Jim ^a   Waugh, Sheela ^a   Gillette, Wendy L ^a   Henninger, Dwight D ^a   Claesson Welsh, Lena ^b   Janjić, Nebojša ^a  

^a GILEAD SCIENCES   (United States)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

AMINO ACID SUBSTITUTION; ANGIOGENESIS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BLOOD VESSEL PERMEABILITY; CONTROLLED STUDY; HORMONE RECEPTOR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; CAPILLARY PERMEABILITY; CELLS, CULTURED; CROSS-LINKING REAGENTS; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; FLUORINE COMPOUNDS; LIGANDS; LYMPHOKINES; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; NEOVASCULARIZATION, PHYSIOLOGIC; OLIGORIBONUCLEOTIDES; PROTEIN BINDING; PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTORS, GROWTH FACTOR; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT PROTEINS; RNA; RNA-BINDING PROTEINS; SWINE; TRANSFECTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

ANIMALIA; MURINAE; SUIDAE;

EID: 0032493654     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.32.20556     Document Type: Article

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