Novel aptamer-nanoparticle bioconjugates enhances delivery of anticancer drug to MUC1-positive cancer cells in vitro

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Yu, Chenchen ^a   Hu, Yan ^a   Duan, Jinhong ^a   Yuan, Wei ^b   Wang, Chen ^c   Xu, Haiyan ^a   Yang, Xian Da ^a,c  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

^b CANCER HOSPITAL   (China)

^c NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; MUCIN 1; NANOPARTICLE; PACLITAXEL; POLYGLACTIN; SPACER DNA; ANTINEOPLASTIC AGENT; DRUG CARRIER; MUC1 PROTEIN, HUMAN;

ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG TARGETING; DRUG UPTAKE; EVAPORATION; FLOW CYTOMETRY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR SIZE; NANOEMULSION; TARGET CELL; CELL STRAIN HEPG2; CHEMISTRY; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; DRUG CARRIERS; HEP G2 CELLS; HUMANS; MUCIN-1; NANOPARTICLES; PACLITAXEL;

EID: 80052349603     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024077     Document Type: Article

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