Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cells

ChemBioChem

Volumn 10, Issue 5, 2009, Pages 862-868

  Huang, Yu Fen ^a   Shangguan, Dihua ^a   Liu, Haipeng ^a   Phillips, Joseph A ^a   Zhang, Xiaoling ^a,b   Chen, Yan ^a   Tan, Weihong ^a  

^a UNIVERSITY OF FLORIDA   (United States)

^b BEIJING INSTITUTE OF TECHNOLOGY   (China)

Author keywords

Anticancer agents; Antitumor agents; Aptamers; Doxorubicin; Drug delivery

Indexed keywords

APTAMER; DOXORUBICIN;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CELL VIABILITY; CONJUGATION; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DOSAGE FORM COMPARISON; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG SPECIFICITY; DRUG TARGETING; DRUG UPTAKE; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; T CELL LEUKEMIA;

ANIMALS; ANTINEOPLASTIC AGENTS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE, TUMOR; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; HUMANS; IMMUNOCONJUGATES; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NEOPLASMS; SELEX APTAMER TECHNIQUE;

EID: 65549102827     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800805     Document Type: Article

References (26)

1. P. J. Carter, P. D. Senter, Cancer J. 2008, 14, 154-169.
2. R. V. J. Chari, Acc. Chem. Res. 2008, 41, 98-107.
3. T. C. Chu, J. W. Marks, L. A. Lavery, S. Faulkner, M. G. Rosenblum, A. D. Ellington, M. Levy, Cancer Res. 2006, 66, 5989-5992.
4. V. Bagalkot, O. C. Farokhzad, R. Langer, S. Jon, Angew. Chem. 2006, 118, 8329-8332;
5. V. Bagalkot, O. C. Farokhzad, R. Langer, S. Jon, Angew. Chem. Int. Ed. 2006, 45, 8149-8152.
6. O. C. Farokhzad, J. M. Karp, R. Langer, Expert Opin. Drug Delivery 2006, 3, 311-324.
7. J. O. McNamara, E. R. Andrechek, Y. Wang, K. D Viles, R. E. Rempel, E. Gilboa, B. A. Sullenger, P. H. Giangrande, Nat. Biotechnol. 2006, 24, 1005-1015.
8. A. D. Ellington, J. W. Szostak, Nature 1990, 346, 818-822.
9. C. Tuerk, L. Gold, Science 1990, 249, 505-510.
10. M. Blank, T. Weinschenk, M. Priemer, H. Schluesener, J. Biol. Chem. 2001, 276, 16464-16468.
11. D. A. Daniels, H. Chen, B. J. Hicke, K. M. Swiderek, L. Gold, Proc. Natl. Acad. Sci. USA 2003, 100, 15416-15421.
12. D. Shangguan, Y. Li, Z. Tang, Z. C. Cao, H. W. Chen, P. Mallikaratchy, K. Sefah, C. J. Yang, W. Tan, Proc. Natl. Acad. Sci. USA 2006, 103, 11838-11843.
13. H. W. Chen, C. D. Medley, K. Sefah, D. Shangguan, Z. W. Tang, L. Meng, J. E. Smith, W. H. Tan, ChemMedChem 2008, 3, 991-1001.
14. D. Shangguan, L. Meng, Z. C. Cao, Z. Xiao, X. Fang, Y. Li, D. Cardona, R. P. Witek, C. Liu, W. Tan, Anal. Chem. 2008, 80, 721-728.
15. D. Shangguan, Z. Cao, L. Meng, P. Mallikaratchy, K. Sefah, H. Wang, Y. Li, W. Tan, J. Proteome Res. 2008, 7, 2133-2139.
16. D. Shangguan, Z. W. Tang, P. Mallikaratchy, Z. Y. Xiao, W. H. Tan, ChemBioChem 2007, 8, 603-606.
17. D. H. Shangguan, Z. H. C. Cao, Y. Li, W. H. Tan, Clin. Chem. 2007, 53, 1153-1155.
18. Z. Y. Xiao, D. H. Shangguan, Z. H. Cao, X. H. Fang, W. H. Tan, Chem. Eur. J. 2008, 14, 1769-1775.
19. R. B. Weiss, G. Sarosy, K. Clagett-Carr, M. Russo, B. Leyland-Jones, Cancer Chemother. Pharmacol. 1986, 18, 185-197.
20. P. H. Wiernik, Current Status and New Developments, Academic Press, New York, 1980.
21. A. Lau, G. Bérubé, C. H. J. Ford, M. Gallant, Bioorg. Med. Chem. 1995, 3, 1305-1312.
22. D. Willner, P. A. Trail, S. J. Hofstead, H. D. King, S. J. Lasch, G. R. Braslawsky, R. S. Greenfield, T. Kaneko, R. A. Firestone, Bioconjugate Chem. 1993, 4, 521-527.
23. Y. Lee, S. Y. Park, H. Mok, T. G. Park, Bioconjugate Chem. 2008, 19, 525-531.
24. Y. Chen, R. J. Walsh, E. A. Arriaga, Anal. Chem. 2005, 77, 2281-2287.
25. A. Dautry-Varsat, C. A, F. L. H, Proc. Natl. Acad. Sci. USA 1983, 80, 2258-2262.
26. G. Payne, Cancer Cell 2003, 3, 207-212.