Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 7, 2008, Pages 2586-2591

  Gu, Frank ^a,b   Zhang, Liangfang ^a   Teply, Benjamin A ^a,c   Mann, Nina ^a   Wang, Andrew ^b,c   Radovic Moreno, Aleksandar F ^a,b   Langer, Robert ^a,b   Farokhzad, Omid C ^a,c  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Aptamer; Chemotherapy; Combinatorial screening; Controlled release

Indexed keywords

AMPHOPHILE; APTAMER; COPOLYMER; MACROGOL; NANOPARTICLE; POLYGLACTIN; PROSTATE SPECIFIC MEMBRANE ANTIGEN; 3 PHENYLACETAMIDO 2,6 PIPERIDINEDIONE; BENZENEACETAMIDE DERIVATIVE; GLYCOLIC ACID DERIVATIVE; LIGAND; MACROGOL DERIVATIVE; PIPERIDONE DERIVATIVE; POLY (LACTIC CO GLYCOLIC ACID); POLY (LACTIC-CO-GLYCOLIC ACID); PROSTATE SPECIFIC ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOENGINEERING; CANCER CELL; CELL SPECIFICITY; CONTROLLED DRUG RELEASE; ENCAPSULATION; KINETICS; MALE; MOUSE; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; SCREENING; ANIMAL; BAGG ALBINO MOUSE; BIOPHYSICS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG SCREENING; ENDOCYTOSIS; HUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUDE MOUSE; SURFACE PROPERTY; TUMOR CELL LINE;

ANIMALS; BENZENEACETAMIDES; BIOPHYSICS; CELL LINE, TUMOR; CHEMISTRY, PHYSICAL; ENDOCYTOSIS; GLYCOLATES; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; MICE, NUDE; MOLECULAR STRUCTURE; NANOPARTICLES; PIPERIDONES; POLYETHYLENE GLYCOLS; PROSTATE-SPECIFIC ANTIGEN; SURFACE PROPERTIES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 40649105534     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0711714105     Document Type: Article

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