Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs

Biomaterials

Volumn 26, Issue 15, 2005, Pages 2713-2722

  Yin Win, Khin ^a   Feng, Si Shen ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Chemotherapy; Confocal laser scanning microscopy (CLSM); Cryo SEM; Drug delivery; Poly(lactic co glycolic acid) (PLGA); Transmission electron microscopy (TEM)

Indexed keywords

ANTICANCER DRUGS; SURFACE CHARGE; SURFACE COATING;

DRUG PRODUCTS; EVAPORATION; MORPHOLOGY; NANOSTRUCTURED MATERIALS; PARTICLE SIZE ANALYSIS; POLYSTYRENES; POLYVINYL ALCOHOLS; SCANNING ELECTRON MICROSCOPY; SURFACE TREATMENT;

TUMORS;

ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; COUMARIN; NANOPARTICLE; POLYGLACTIN; POLYMER; POLYSTYRENE; POLYVINYL ALCOHOL;

ARTICLE; BIODEGRADABILITY; CANCER CELL CULTURE; CHEMOTHERAPY; COLON ADENOCARCINOMA; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EVAPORATION; HUMAN; HUMAN CELL; LASER MICROSCOPY; LIGHT SCATTERING; MORPHOLOGY; PARTICLE SIZE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCANNING ELECTRON MICROSCOPY; SOLVENT EXTRACTION; SPECTROFLUOROMETRY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

ADMINISTRATION, ORAL; ANTINEOPLASTIC AGENTS; CACO-2 CELLS; COATED MATERIALS, BIOCOMPATIBLE; DIFFUSION; ENDOCYTOSIS; HUMANS; LACTIC ACID; MATERIALS TESTING; NANOTUBES; PARTICLE SIZE; POLYGLYCOLIC ACID; POLYMERS; VITAMIN E;

POTATO VIRUS A;

EID: 10044225776     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2004.07.050     Document Type: Article

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