Ligand-specific targeting of microspheres to phagocytes by surface modification with poly(L-lysine)-grafted poly(ethylene glycol) conjugate

Pharmaceutical Research

Volumn 20, Issue 2, 2003, Pages 237-246

  Faraasen, Sofia ^a,b   Vörös, János ^b   Csúcs, Gábor ^b   Textor, Marcus ^b   Merkle, Hans P ^b   Walter, Elke ^b  

^a LINKÖPING UNIVERSITY   (Sweden)

^b ETH ZURICH   (Switzerland)

Author keywords

Phagocytosis; Poly(D,L, lactide co glycolide) (PLGA) microspheres; Poly(L lysine) grafted poly(ethylene glycol) (PLL g PEG); RGD peptide; Surface modification

Indexed keywords

DRUG RECEPTOR; GLASS; LIGAND; MACROGOL; MICROSPHERE; POLYGLACTIN; POLYLYSINE; POLYMER; POLYSTYRENE;

ADSORPTION; ARTICLE; CELL ADHESION; CELL SPREADING; CONTROLLED STUDY; DENDRITIC CELL; DRUG CONJUGATION; DRUG INHIBITION; ELECTRICITY; HUMAN; HUMAN CELL; MACROPHAGE; MATERIAL COATING; MODEL; MOLECULAR RECOGNITION; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; PRIORITY JOURNAL; SERUM; TARGET CELL;

CELLS, CULTURED; DRUG DELIVERY SYSTEMS; HUMANS; LIGANDS; MICROSPHERES; PHAGOCYTES; POLYETHYLENE GLYCOLS; POLYLYSINE; SURFACE PROPERTIES;

EID: 0037331755     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022366921298     Document Type: Article

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