An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform

Angewandte Chemie - International Edition

Volumn 45, Issue 48, 2006, Pages 8149-8152

  Bagalkot, Vaishali ^a,b   Farokhzad, Omid C ^b   Langer, Robert ^c   Jon, Sangyong ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

Antitumor agents; Aptamers; Conjugation; Drug delivery; Targeted therapy

Indexed keywords

ANTIGENS; BIOLOGICAL MEMBRANES; CELLS; CONTROLLED DRUG DELIVERY; RNA; TUMORS;

ANTITUMOR AGENTS; APTAMERS; TARGETED THERAPY;

ORGANIC POLYMERS;

ANTINEOPLASTIC AGENT; APTAMER; DOXORUBICIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CONFOCAL MICROSCOPY; DRUG DELIVERY SYSTEM; HUMAN; METABOLISM; METHODOLOGY; PLASMA CELL LEUKEMIA;

ANTINEOPLASTIC AGENTS; APTAMERS, NUCLEOTIDE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; HUMANS; LEUKEMIA, PLASMACYTIC; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE;

EID: 33845723241     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200602251     Document Type: Article

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