-
1
-
-
34147182401
-
Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging
-
Adams PD. 2007. Remodeling of chromatin structure in senescent cells and its potential impact on tumor suppression and aging. Gene 397:84-93.
-
(2007)
Gene
, vol.397
, pp. 84-93
-
-
Adams, P.D.1
-
2
-
-
0026001046
-
CpG islands: Features and distribution in the genomes of vertebrates
-
Aïssani B, Bernardi G. 1991. CpG islands: Features and distribution in the genomes of vertebrates. Gene 106:173-183.
-
(1991)
Gene
, vol.106
, pp. 173-183
-
-
Aïssani, B.1
Bernardi, G.2
-
3
-
-
39049158763
-
Epigenetic gene regulation in cancer
-
Ballestar E, Esteller M. 2008. Epigenetic gene regulation in cancer. Adv Genet 61:247-267.
-
(2008)
Adv Genet
, vol.61
, pp. 247-267
-
-
Ballestar, E.1
Esteller, M.2
-
4
-
-
0035169663
-
Methyl-CpG-binding proteins. Targeting specific gene repression
-
Ballestar E, Wolffe AP. 2001. Methyl-CpG-binding proteins. Targeting specific gene repression. Eur J Biochem 268:1-6.
-
(2001)
Eur J Biochem
, vol.268
, pp. 1-6
-
-
Ballestar, E.1
Wolffe, A.P.2
-
5
-
-
0035282458
-
Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain
-
Bannister AJ, Zegerman P, Partridge JF, Miska EA, Thomas JO, Allshire RC, Kouzarides T. 2001. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain. Nature 410:120-124.
-
(2001)
Nature
, vol.410
, pp. 120-124
-
-
Bannister, A.J.1
Zegerman, P.2
Partridge, J.F.3
Miska, E.A.4
Thomas, J.O.5
Allshire, R.C.6
Kouzarides, T.7
-
6
-
-
79955090200
-
BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest
-
Bartlett C, Orvis TJ, Rosson GS, Weissman BE. 2011. BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest. J Cell Physiol 226:1989-1997.
-
(2011)
J Cell Physiol
, vol.226
, pp. 1989-1997
-
-
Bartlett, C.1
Orvis, T.J.2
Rosson, G.S.3
Weissman, B.E.4
-
7
-
-
33644846509
-
Epigenetic gene silencing in cancer--A mechanism for early oncogenic pathway addiction
-
Baylin SB, Ohm JE. 2006. Epigenetic gene silencing in cancer--A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6:107-116.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 107-116
-
-
Baylin, S.B.1
Ohm, J.E.2
-
8
-
-
33846590977
-
Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres
-
Benetti R, García-Cao M, Blasco MA. 2007a. Telomere length regulates the epigenetic status of mammalian telomeres and subtelomeres. Nat Genet 39:243-250.
-
(2007)
Nat Genet
, vol.39
, pp. 243-250
-
-
Benetti, R.1
García-Cao, M.2
Blasco, M.A.3
-
9
-
-
34548827379
-
Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination
-
Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, Blasco MA. 2007b. Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol 178:925-936.
-
(2007)
J Cell Biol
, vol.178
, pp. 925-936
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Schotta, G.4
Klatt, P.5
Jenuwein, T.6
Blasco, M.A.7
-
10
-
-
40949100837
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
-
Benetti R, Gonzalo S, Jaco I, Muñoz P, Gonzalez S, Schoeftner S, Murchison E, Andl T, Chen T, Klatt P, Li E, Serrano M, Millar S, Hannon G, Blasco MA. 2008. A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat Struct Mol Biol 15:268-279.
-
(2008)
Nat Struct Mol Biol
, vol.15
, pp. 268-279
-
-
Benetti, R.1
Gonzalo, S.2
Jaco, I.3
Muñoz, P.4
Gonzalez, S.5
Schoeftner, S.6
Murchison, E.7
Andl, T.8
Chen, T.9
Klatt, P.10
Li, E.11
Serrano, M.12
Millar, S.13
Hannon, G.14
Blasco, M.A.15
-
11
-
-
20444429760
-
Binding of pRB to the PHD Protein RBP2 Promotes Cellular Differentiation
-
Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG, Jr. 2005. Binding of pRB to the PHD Protein RBP2 Promotes Cellular Differentiation. Mol Cell 18:623-635.
-
(2005)
Mol Cell
, vol.18
, pp. 623-635
-
-
Benevolenskaya, E.V.1
Murray, H.L.2
Branton, P.3
Young, R.A.4
Kaelin Jr., W.G.5
-
12
-
-
34249299791
-
The complex language of chromatin regulation during transcription
-
Berger SL. 2007. The complex language of chromatin regulation during transcription. Nature 447:407-412.
-
(2007)
Nature
, vol.447
, pp. 407-412
-
-
Berger, S.L.1
-
13
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird AP. 1986. CpG-rich islands and the function of DNA methylation. Nature 321:209-213.
-
(1986)
Nature
, vol.321
, pp. 209-213
-
-
Bird, A.P.1
-
14
-
-
0033601073
-
Methylation-induced repression--Belts, braces, and chromatin
-
Bird AP, Wolffe AP. 1999. Methylation-induced repression--Belts, braces, and chromatin. Cell 99:451-454.
-
(1999)
Cell
, vol.99
, pp. 451-454
-
-
Bird, A.P.1
Wolffe, A.P.2
-
15
-
-
0034597794
-
Telomere states and cell fates
-
Blackburn EH. 2000. Telomere states and cell fates. Nature 408:53-56.
-
(2000)
Nature
, vol.408
, pp. 53-56
-
-
Blackburn, E.H.1
-
16
-
-
3242766201
-
Carcinogenesis Young Investigator Award. Telomere epigenetics: A higher-order control of telomere length in mammalian cells
-
Blasco MA. 2004. Carcinogenesis Young Investigator Award. Telomere epigenetics: A higher-order control of telomere length in mammalian cells. Carcinogenesis 25:1083-1087.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1083-1087
-
-
Blasco, M.A.1
-
17
-
-
0030931491
-
Telomere shortening and tumor formation by mouse cells lacking telomerase RNA
-
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW. 1997. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell 91:25-34.
-
(1997)
Cell
, vol.91
, pp. 25-34
-
-
Blasco, M.A.1
Lee, H.W.2
Hande, M.P.3
Samper, E.4
Lansdorp, P.M.5
DePinho, R.A.6
Greider, C.W.7
-
18
-
-
0032484989
-
Retinoblastoma protein recruits histone deacetylase to repress transcription
-
Brehm A, Miska EA, McCance DJ, Reid JL, Bannister AJ, Kouzarides T. 1998. Retinoblastoma protein recruits histone deacetylase to repress transcription. Nature 391:597-601.
-
(1998)
Nature
, vol.391
, pp. 597-601
-
-
Brehm, A.1
Miska, E.A.2
McCance, D.J.3
Reid, J.L.4
Bannister, A.J.5
Kouzarides, T.6
-
19
-
-
27744547290
-
Maintenance and regulation of DNA methylation patterns in mammals
-
Chen Z-X, Riggs AD. 2005. Maintenance and regulation of DNA methylation patterns in mammals. Biochem Cell Biol 83:438-448.
-
(2005)
Biochem Cell Biol
, vol.83
, pp. 438-448
-
-
Chen, Z.-X.1
Riggs, A.D.2
-
20
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b
-
Chen T, Ueda Y, Dodge JE, Wang Z, Li E. 2003. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol Cell Biol 23:5594-5605.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
21
-
-
0141992114
-
Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase
-
Clements A, Poux AN, Lo W-S, Pillus L, Berger SL, Marmorstein R. 2003. Structural basis for histone and phosphohistone binding by the GCN5 histone acetyltransferase. Mol Cell 12:461-473.
-
(2003)
Mol Cell
, vol.12
, pp. 461-473
-
-
Clements, A.1
Poux, A.N.2
Lo, W.-S.3
Pillus, L.4
Berger, S.L.5
Marmorstein, R.6
-
22
-
-
0037459109
-
Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling
-
Cleveland DW, Mao Y, Sullivan KF. 2003. Centromeres and kinetochores: From epigenetics to mitotic checkpoint signaling. Cell 112:407-421.
-
(2003)
Cell
, vol.112
, pp. 407-421
-
-
Cleveland, D.W.1
Mao, Y.2
Sullivan, K.F.3
-
23
-
-
73249140326
-
DNA methylation programming and reprogramming in primate embryonic stem cells
-
Cohen N, Dighe V, Landan G, Reynisdóttir S, Palsson A, Mitalipov S, Tanay A. 2009. DNA methylation programming and reprogramming in primate embryonic stem cells. Genome Res 19:2193-2201.
-
(2009)
Genome Res
, vol.19
, pp. 2193-2201
-
-
Cohen, N.1
Dighe, V.2
Landan, G.3
Reynisdóttir, S.4
Palsson, A.5
Mitalipov, S.6
Tanay, A.7
-
24
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino S, Xu J, Sannai M, Moore R, Caretti E, Cigliano A, Le Coz M, Devarajan K, Wesseks A, Soprano D, Abramowitz LK. 2011. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146:67-79.
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
Xu, J.2
Sannai, M.3
Moore, R.4
Caretti, E.5
Cigliano, A.6
Le Coz, M.7
Devarajan, K.8
Wesseks, A.9
Soprano, D.10
Abramowitz, L.K.11
-
25
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello JF, Frühwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomaki P, Lag JC, Schuller LY, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Huang HS, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C. 2000. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24:132-138.
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Frühwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lag, J.C.10
Schuller, L.Y.11
Bloomfield, C.D.12
Caligiuri, M.A.13
Yates, A.14
Nishikawa, R.15
Huang, H.S.16
Petrelli, N.J.17
Zhang, X.18
O'Dorisio, M.S.19
Held, W.A.20
Cavenee, W.K.21
Plass, C.22
more..
-
26
-
-
4444372638
-
Histone deimination antagonizes arginine methylation
-
Cuthbert GL, Daujat S, Snowden AW, Erdjument-Bromage H, Hagiwara T, Yamada M, Schneider R, Gregory PD, Tempst P, Bannister AJ, Kouzarides T. 2004. Histone deimination antagonizes arginine methylation. Cell 118:545-553.
-
(2004)
Cell
, vol.118
, pp. 545-553
-
-
Cuthbert, G.L.1
Daujat, S.2
Snowden, A.W.3
Erdjument-Bromage, H.4
Hagiwara, T.5
Yamada, M.6
Schneider, R.7
Gregory, P.D.8
Tempst, P.9
Bannister, A.J.10
Kouzarides, T.11
-
27
-
-
13844252061
-
The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment
-
Dai J, Sultan S, Taylor SS, Higgins JMG. 2005. The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes Dev 19:472-488.
-
(2005)
Genes Dev
, vol.19
, pp. 472-488
-
-
Dai, J.1
Sultan, S.2
Taylor, S.S.3
Higgins, J.M.G.4
-
28
-
-
0037324703
-
Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer
-
Dean W, Santos F, Reik W. 2003. Epigenetic reprogramming in early mammalian development and following somatic nuclear transfer. Semin Cell Dev Biol 14:93-100.
-
(2003)
Semin Cell Dev Biol
, vol.14
, pp. 93-100
-
-
Dean, W.1
Santos, F.2
Reik, W.3
-
29
-
-
0028060515
-
The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest
-
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. 1994. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell 79:119-130.
-
(1994)
Cell
, vol.79
, pp. 119-130
-
-
Dunaief, J.L.1
Strober, B.E.2
Guha, S.3
Khavari, P.A.4
Alin, K.5
Luban, J.6
Begemann, M.7
Crabtree, G.R.8
Goff, S.P.9
-
30
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger G, Liang G, Aparicio A, Jones PA. 2004. Epigenetics in human disease and prospects for epigenetic therapy. Nature 429:457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
Liang, G.2
Aparicio, A.3
Jones, P.A.4
-
31
-
-
33748998743
-
Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival
-
Egger G, Jeong S, Escobar SG, Cortez CC, Li TWH, Saito Y, Yoo CB, Jones PA, Liang G. 2006. Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival. Proc Natl Acad Sci USA 103:14080-14085.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 14080-14085
-
-
Egger, G.1
Jeong, S.2
Escobar, S.G.3
Cortez, C.C.4
Li, T.W.H.5
Saito, Y.6
Yoo, C.B.7
Jones, P.A.8
Liang, G.9
-
32
-
-
42449129744
-
Cytosine methylation profiling of cancer cell lines
-
Ehrich M, Turner J, Gibbs P, Lipton L, Giovanneti M, Cantor C, van den Boom D. 2008. Cytosine methylation profiling of cancer cell lines. Proc Natl Acad Sci USA 105:4844-4849.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 4844-4849
-
-
Ehrich, M.1
Turner, J.2
Gibbs, P.3
Lipton, L.4
Giovanneti, M.5
Cantor, C.6
van den Boom, D.7
-
33
-
-
33947315736
-
Cancer epigenomics: DNA methylomes and histone-modification maps
-
Esteller M. 2007. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat Rev Genet 8:286-298.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 286-298
-
-
Esteller, M.1
-
35
-
-
0033842950
-
Genetic and epigenetic changes in human epithelial cells immortalized by telomerase
-
Farwell DG, Shera KA, Koop JI, Bonnet GA, Matthews CP, Reuther GW, Coltrera MD, McDougall JK, Klingelhutz AJ. 2000. Genetic and epigenetic changes in human epithelial cells immortalized by telomerase. Am J Pathol 156:1537-1547.
-
(2000)
Am J Pathol
, vol.156
, pp. 1537-1547
-
-
Farwell, D.G.1
Shera, K.A.2
Koop, J.I.3
Bonnet, G.A.4
Matthews, C.P.5
Reuther, G.W.6
Coltrera, M.D.7
McDougall, J.K.8
Klingelhutz, A.J.9
-
36
-
-
40949093544
-
Epigenetics at the epicenter of modern medicine
-
Feinberg AP. 2008. Epigenetics at the epicenter of modern medicine. JAMA 299:1345-1350.
-
(2008)
JAMA
, vol.299
, pp. 1345-1350
-
-
Feinberg, A.P.1
-
37
-
-
1042278765
-
The history of cancer epigenetics
-
Feinberg AP, Tycko B. 2004. The history of cancer epigenetics. Nat Rev Cancer 4:143-153.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 143-153
-
-
Feinberg, A.P.1
Tycko, B.2
-
39
-
-
0026599021
-
Chromatin as an essential part of the transcriptional mechanism
-
Felsenfeld G. 1992. Chromatin as an essential part of the transcriptional mechanism. Nature 355:219-224.
-
(1992)
Nature
, vol.355
, pp. 219-224
-
-
Felsenfeld, G.1
-
40
-
-
50149109481
-
Epigenetic reprogramming by adenovirus e1a
-
Ferrari R, Pellegrini M, Horwitz GA, Xie W, Berk AJ, Kurdistani SK. 2008. Epigenetic reprogramming by adenovirus e1a. Science 321:1086-1088.
-
(2008)
Science
, vol.321
, pp. 1086-1088
-
-
Ferrari, R.1
Pellegrini, M.2
Horwitz, G.A.3
Xie, W.4
Berk, A.J.5
Kurdistani, S.K.6
-
41
-
-
0032168984
-
The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase
-
Ferreira R, Magnaghi-Jaulin L, Robin P, Harel-Bellan A, Trouche D. 1998. The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase. Proc Natl Acad Sci USA 95:10493-10498.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 10493-10498
-
-
Ferreira, R.1
Magnaghi-Jaulin, L.2
Robin, P.3
Harel-Bellan, A.4
Trouche, D.5
-
42
-
-
0034740556
-
Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter
-
Ferreira R, Naguibneva I, Mathieu M, Ait-Si-Ali S, Robin P, Pritchard LL, Harel-Bellan A. 2001. Cell cycle-dependent recruitment of HDAC-1 correlates with deacetylation of histone H4 on an Rb-E2F target promoter. EMBO Rep 2:794-799.
-
(2001)
EMBO Rep
, vol.2
, pp. 794-799
-
-
Ferreira, R.1
Naguibneva, I.2
Mathieu, M.3
Ait-Si-Ali, S.4
Robin, P.5
Pritchard, L.L.6
Harel-Bellan, A.7
-
43
-
-
33645218438
-
A family of human zinc finger proteins that bind methylated DNA and repress transcription
-
Filion GJP, Zhenilo S, Salozhin S, Yamada D, Prokhortchouk E, Defossez P-A. 2006. A family of human zinc finger proteins that bind methylated DNA and repress transcription. Mol Cell Biol 26:169-181.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 169-181
-
-
Filion, G.J.P.1
Zhenilo, S.2
Salozhin, S.3
Yamada, D.4
Prokhortchouk, E.5
Defossez, P.-A.6
-
45
-
-
28844477653
-
Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation
-
Fischle W, Tseng BS, Dormann HL, Ueberheide BM, Garcia BA, Shabanowitz J, Hunt DF, Funabiki H, Allis CD. 2005. Regulation of HP1-chromatin binding by histone H3 methylation and phosphorylation. Nature 438:1116-1122.
-
(2005)
Nature
, vol.438
, pp. 1116-1122
-
-
Fischle, W.1
Tseng, B.S.2
Dormann, H.L.3
Ueberheide, B.M.4
Garcia, B.A.5
Shabanowitz, J.6
Hunt, D.F.7
Funabiki, H.8
Allis, C.D.9
-
46
-
-
78449273419
-
Transcriptional activation by pRB and its coordination with SWI/SNF recruitment
-
Flowers S, Beck GR, Moran E. 2010. Transcriptional activation by pRB and its coordination with SWI/SNF recruitment. Cancer Res 70:8282-8287.
-
(2010)
Cancer Res
, vol.70
, pp. 8282-8287
-
-
Flowers, S.1
Beck, G.R.2
Moran, E.3
-
47
-
-
26444573127
-
Towards the human cancer epigenome: A first draft of histone modifications
-
Fraga MF, Esteller M. 2005. Towards the human cancer epigenome: A first draft of histone modifications. Cell Cycle 4:1377-1381.
-
(2005)
Cell Cycle
, vol.4
, pp. 1377-1381
-
-
Fraga, M.F.1
Esteller, M.2
-
48
-
-
0033615636
-
A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin
-
Francastel C, Walters MC, Groudine M, Martin DI. 1999. A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin. Cell 99:259-269.
-
(1999)
Cell
, vol.99
, pp. 259-269
-
-
Francastel, C.1
Walters, M.C.2
Groudine, M.3
Martin, D.I.4
-
49
-
-
0038412822
-
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
-
Fuks F, Hurd PJ, Deplus R, Kouzarides T. 2003a. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 31:2305-2312.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
50
-
-
0037423186
-
The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation
-
Fuks F, Hurd PJ, Wolf D, Nan X, Bird AP, Kouzarides T. 2003b. The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation. J Biol Chem 278:4035-4040.
-
(2003)
J Biol Chem
, vol.278
, pp. 4035-4040
-
-
Fuks, F.1
Hurd, P.J.2
Wolf, D.3
Nan, X.4
Bird, A.P.5
Kouzarides, T.6
-
51
-
-
34648816970
-
Cellular senescence and chromatin structure
-
Funayama R, Ishikawa F. 2007. Cellular senescence and chromatin structure. Chromosoma 116:431-440.
-
(2007)
Chromosoma
, vol.116
, pp. 431-440
-
-
Funayama, R.1
Ishikawa, F.2
-
52
-
-
0036613432
-
Role for DNA methylation in the control of cell type-specific maspin expression
-
Futscher BW, Oshiro MM, Wozniak RJ, Holtan N, Hanigan CL, Duan H, Domann FE. 2002. Role for DNA methylation in the control of cell type-specific maspin expression. Nat Genet 31:175-179.
-
(2002)
Nat Genet
, vol.31
, pp. 175-179
-
-
Futscher, B.W.1
Oshiro, M.M.2
Wozniak, R.J.3
Holtan, N.4
Hanigan, C.L.5
Duan, H.6
Domann, F.E.7
-
53
-
-
0036843088
-
A role for the Rb family of proteins in controlling telomere length
-
García-Cao M, Gonzalo S, Dean D, Blasco MA. 2002. A role for the Rb family of proteins in controlling telomere length. Nat Genet 32:415-419.
-
(2002)
Nat Genet
, vol.32
, pp. 415-419
-
-
García-Cao, M.1
Gonzalo, S.2
Dean, D.3
Blasco, M.A.4
-
54
-
-
0347988045
-
Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases
-
García-Cao M, O'Sullivan R, Peters AHFM, Jenuwein T, Blasco MA. 2004. Epigenetic regulation of telomere length in mammalian cells by the Suv39h1 and Suv39h2 histone methyltransferases. Nat Genet 36:94-99.
-
(2004)
Nat Genet
, vol.36
, pp. 94-99
-
-
García-Cao, M.1
O'Sullivan, R.2
Peters, A.H.F.M.3
Jenuwein, T.4
Blasco, M.A.5
-
55
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M. 1987. CpG islands in vertebrate genomes. J Mol Biol 196:261-282.
-
(1987)
J Mol Biol
, vol.196
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
56
-
-
0034717045
-
A sense of the end
-
Gasser SM. 2000. A sense of the end. Science 288:1377-1379.
-
(2000)
Science
, vol.288
, pp. 1377-1379
-
-
Gasser, S.M.1
-
57
-
-
0242584449
-
Induction of tumors in mice by genomic hypomethylation
-
Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R. 2003. Induction of tumors in mice by genomic hypomethylation. Science 300:489-492.
-
(2003)
Science
, vol.300
, pp. 489-492
-
-
Gaudet, F.1
Hodgson, J.G.2
Eden, A.3
Jackson-Grusby, L.4
Dausman, J.5
Gray, J.W.6
Leonhardt, H.7
Jaenisch, R.8
-
58
-
-
33847047461
-
Epigenetics: A landscape takes shape
-
Goldberg AD, Allis CD, Bernstein E. 2007. Epigenetics: A landscape takes shape. Cell 128:635-638.
-
(2007)
Cell
, vol.128
, pp. 635-638
-
-
Goldberg, A.D.1
Allis, C.D.2
Bernstein, E.3
-
59
-
-
84863277661
-
Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1
-
Gong W, Zhou T, Mo J, Perrett S, Wang J, Feng Y. 2012. Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1. J Biol Chem 287:8531-8540.
-
(2012)
J Biol Chem
, vol.287
, pp. 8531-8540
-
-
Gong, W.1
Zhou, T.2
Mo, J.3
Perrett, S.4
Wang, J.5
Feng, Y.6
-
60
-
-
25144491542
-
Role of Rb family in the epigenetic definition of chromatin
-
Gonzalo S, Blasco MA. 2005. Role of Rb family in the epigenetic definition of chromatin. Cell Cycle 4:752-755.
-
(2005)
Cell Cycle
, vol.4
, pp. 752-755
-
-
Gonzalo, S.1
Blasco, M.A.2
-
61
-
-
20244376464
-
Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin
-
Gonzalo S, García-Cao M, Fraga MF, Schotta G, Peters AHFM, Cotter SE, Eguia R, Dean DC, Esteller M, Jenuwein T, Blasco MA. 2005. Role of the RB1 family in stabilizing histone methylation at constitutive heterochromatin. Nat Cell Biol 7:420-428.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 420-428
-
-
Gonzalo, S.1
García-Cao, M.2
Fraga, M.F.3
Schotta, G.4
Peters, A.H.F.M.5
Cotter, S.E.6
Eguia, R.7
Dean, D.C.8
Esteller, M.9
Jenuwein, T.10
Blasco, M.A.11
-
62
-
-
33645702660
-
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
-
Gonzalo S, Jaco I, Fraga MF, Chen T, Li E, Esteller M, Blasco MA. 2006. DNA methyltransferases control telomere length and telomere recombination in mammalian cells. Nat Cell Biol 8:416-424.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 416-424
-
-
Gonzalo, S.1
Jaco, I.2
Fraga, M.F.3
Chen, T.4
Li, E.5
Esteller, M.6
Blasco, M.A.7
-
63
-
-
0025201982
-
Position effect at S. Cerevisiae telomeres: Reversible repression of Pol II transcription
-
Gottschling DE, Aparicio OM, Billington BL, Zakian VA. 1990. Position effect at S. Cerevisiae telomeres: Reversible repression of Pol II transcription. Cell 63:751-762.
-
(1990)
Cell
, vol.63
, pp. 751-762
-
-
Gottschling, D.E.1
Aparicio, O.M.2
Billington, B.L.3
Zakian, V.A.4
-
64
-
-
0344193100
-
Life with nucleosomes: Chromatin remodelling in gene regulation
-
Gregory PD, Hörz W. 1998. Life with nucleosomes: Chromatin remodelling in gene regulation. Curr Opin Cell Biol 10:339-345.
-
(1998)
Curr Opin Cell Biol
, vol.10
, pp. 339-345
-
-
Gregory, P.D.1
Hörz, W.2
-
65
-
-
33847076248
-
Chromatin challenges during DNA replication and repair
-
Groth A, Rocha W, Verreault A, Almouzni G. 2007. Chromatin challenges during DNA replication and repair. Cell 128:721-733.
-
(2007)
Cell
, vol.128
, pp. 721-733
-
-
Groth, A.1
Rocha, W.2
Verreault, A.3
Almouzni, G.4
-
67
-
-
33749260519
-
Nuclear ADP-ribosylation reactions in mammalian cells: Where are we today and where are we going
-
Hassa PO, Haenni SS, Elser M, Hottiger MO. 2006. Nuclear ADP-ribosylation reactions in mammalian cells: Where are we today and where are we going? Microbiol Mol Biol Rev 70:789-829.
-
(2006)
Microbiol Mol Biol Rev
, vol.70
, pp. 789-829
-
-
Hassa, P.O.1
Haenni, S.S.2
Elser, M.3
Hottiger, M.O.4
-
68
-
-
0035861875
-
Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation
-
Heard E, Rougeulle C, Arnaud D, Avner P, Allis CD, Spector DL. 2001. Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell 107:727-738.
-
(2001)
Cell
, vol.107
, pp. 727-738
-
-
Heard, E.1
Rougeulle, C.2
Arnaud, D.3
Avner, P.4
Allis, C.D.5
Spector, D.L.6
-
69
-
-
68049097008
-
Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal
-
Hemberger M, Dean W, Reik W. 2009. Epigenetic dynamics of stem cells and cell lineage commitment: Digging Waddington's canal. Nat Rev Mol Cell Biol 10:526-537.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 526-537
-
-
Hemberger, M.1
Dean, W.2
Reik, W.3
-
70
-
-
0031792779
-
Identification and characterization of a family of mammalian methyl-CpG binding proteins
-
Hendrich B, Bird A. 1998. Identification and characterization of a family of mammalian methyl-CpG binding proteins. Mol Cell Biol 18:6538-6547.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 6538-6547
-
-
Hendrich, B.1
Bird, A.2
-
71
-
-
0035839066
-
The centromere paradox: Stable inheritance with rapidly evolving DNA
-
Henikoff S, Ahmad K, Malik HS. 2001. The centromere paradox: Stable inheritance with rapidly evolving DNA. Science 293:1098-1102.
-
(2001)
Science
, vol.293
, pp. 1098-1102
-
-
Henikoff, S.1
Ahmad, K.2
Malik, H.S.3
-
72
-
-
9144256125
-
The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
-
Hermann A, Goyal R, Jeltsch A. 2004. The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites. J Biol Chem 279:48350-48359.
-
(2004)
J Biol Chem
, vol.279
, pp. 48350-48359
-
-
Hermann, A.1
Goyal, R.2
Jeltsch, A.3
-
73
-
-
31544467813
-
De novo CpG island methylation in human cancer cells
-
Jair K-W, Bachman KE, Suzuki H, Ting AH, Rhee I, Yen R-WC, Baylin SB, Schebel KE. 2006. De novo CpG island methylation in human cancer cells. Cancer Res 66:682-692.
-
(2006)
Cancer Res
, vol.66
, pp. 682-692
-
-
Jair, K.-W.1
Bachman, K.E.2
Suzuki, H.3
Ting, A.H.4
Rhee, I.5
Yen, R.-W.6
Baylin, S.B.7
Schebel, K.E.8
-
74
-
-
29644436321
-
Molecular enzymology of mammalian DNA methyltransferases
-
Jeltsch A. 2006. Molecular enzymology of mammalian DNA methyltransferases. Curr Top Microbiol Immunol 301:203-225.
-
(2006)
Curr Top Microbiol Immunol
, vol.301
, pp. 203-225
-
-
Jeltsch, A.1
-
75
-
-
0035839136
-
Translating the histone code
-
Jenuwein T, Allis CD. 2001. Translating the histone code. Science 293:1074-1080.
-
(2001)
Science
, vol.293
, pp. 1074-1080
-
-
Jenuwein, T.1
Allis, C.D.2
-
76
-
-
70349322609
-
Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA
-
Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA. 2009. Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA. Mol Cell Biol 29:5366-5376.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5366-5376
-
-
Jeong, S.1
Liang, G.2
Sharma, S.3
Lin, J.C.4
Choi, S.H.5
Han, H.6
Yoo, C.B.7
Egger, G.8
Yang, A.S.9
Jones, P.A.10
-
77
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. 2007. The epigenomics of cancer. Cell 128:683-692.
-
(2007)
Cell
, vol.128
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
78
-
-
0032488855
-
Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines
-
Kadonaga JT. 1998. Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines. Cell 92:307-313.
-
(1998)
Cell
, vol.92
, pp. 307-313
-
-
Kadonaga, J.T.1
-
79
-
-
40449104358
-
Transient cyclical methylation of promoter DNA
-
Kangaspeska S, Stride B, Métivier R, Polycarpou-Schwarz M, Ibberson D, Carmouche RP, Benes V, Gannon F, Reid G. 2008. Transient cyclical methylation of promoter DNA. Nature 452:112-115.
-
(2008)
Nature
, vol.452
, pp. 112-115
-
-
Kangaspeska, S.1
Stride, B.2
Métivier, R.3
Polycarpou-Schwarz, M.4
Ibberson, D.5
Carmouche, R.P.6
Benes, V.7
Gannon, F.8
Reid, G.9
-
80
-
-
0022545498
-
DNA methylation affects the formation of active chromatin
-
Keshet I, Lieman-Hurwitz J, Cedar H. 1986. DNA methylation affects the formation of active chromatin. Cell 44:535-543.
-
(1986)
Cell
, vol.44
, pp. 535-543
-
-
Keshet, I.1
Lieman-Hurwitz, J.2
Cedar, H.3
-
81
-
-
0036683055
-
Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
-
Kim G-D, Ni J, Kelesoglu N, Roberts RJ, Pradhan S. 2002. Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases. EMBO J 21:4183-4195.
-
(2002)
EMBO J
, vol.21
, pp. 4183-4195
-
-
Kim, G.-D.1
Ni, J.2
Kelesoglu, N.3
Roberts, R.J.4
Pradhan, S.5
-
82
-
-
70350044885
-
DNA demethylation in hormone-induced transcriptional derepression
-
Kim M-S, Kondo T, Takada I, Youn M-Y, Yamamoto Y, Takahashi S, Matsumoto T, Fujiyama S, Shirode Y, Yamaoka I, Kitagawa H, Takeyama K-I, Shibuya H, Ohtake F, Kato S. 2009. DNA demethylation in hormone-induced transcriptional derepression. Nature 461:1007-1012.
-
(2009)
Nature
, vol.461
, pp. 1007-1012
-
-
Kim, M.-S.1
Kondo, T.2
Takada, I.3
Youn, M.-Y.4
Yamamoto, Y.5
Takahashi, S.6
Matsumoto, T.7
Fujiyama, S.8
Shirode, Y.9
Yamaoka, I.10
Kitagawa, H.11
Takeyama, K.-I.12
Shibuya, H.13
Ohtake, F.14
Kato, S.15
-
83
-
-
0037148342
-
Telomeres, aging and cancer: In search of a happy ending
-
Kim Sh S-H, Kaminker P, Campisi J. 2002. Telomeres, aging and cancer: In search of a happy ending. Oncogene 21:503-511.
-
(2002)
Oncogene
, vol.21
, pp. 503-511
-
-
Kim Sh, S.-H.1
Kaminker, P.2
Campisi, J.3
-
84
-
-
0033568312
-
ATP-dependent remodeling and acetylation as regulators of chromatin fluidity
-
Kingston RE, Narlikar GJ. 1999. ATP-dependent remodeling and acetylation as regulators of chromatin fluidity. Genes Dev 13:2339-2352.
-
(1999)
Genes Dev
, vol.13
, pp. 2339-2352
-
-
Kingston, R.E.1
Narlikar, G.J.2
-
85
-
-
12344289259
-
Kinetochore-spindle microtubule interactions during mitosis
-
Kline-Smith SL, Sandall S, Desai A. 2005. Kinetochore-spindle microtubule interactions during mitosis. Curr Opin Cell Biol 17:35-46.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 35-46
-
-
Kline-Smith, S.L.1
Sandall, S.2
Desai, A.3
-
86
-
-
33846148370
-
pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene
-
Kotake Y, Cao R, Viatour P, Sage J, Zhang Y, Xiong Y. 2007. pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene. Genes Dev 21:49-54.
-
(2007)
Genes Dev
, vol.21
, pp. 49-54
-
-
Kotake, Y.1
Cao, R.2
Viatour, P.3
Sage, J.4
Zhang, Y.5
Xiong, Y.6
-
87
-
-
3042858906
-
Heterochromatin and tri-methylated lysine 20 of histone H4 in animals
-
Kourmouli N, Jeppesen P, Mahadevhaiah S, Burgoyne P, Wu R, Gilbert DM, Bongiorni S, Prantera G, Fanti L, Pimpinelli S, Shi W, Fundele R, Singh PB. 2004. Heterochromatin and tri-methylated lysine 20 of histone H4 in animals. J Cell Sci 117:2491-2501.
-
(2004)
J Cell Sci
, vol.117
, pp. 2491-2501
-
-
Kourmouli, N.1
Jeppesen, P.2
Mahadevhaiah, S.3
Burgoyne, P.4
Wu, R.5
Gilbert, D.M.6
Bongiorni, S.7
Prantera, G.8
Fanti, L.9
Pimpinelli, S.10
Shi, W.11
Fundele, R.12
Singh, P.B.13
-
88
-
-
33847076849
-
Chromatin modifications and their function
-
Kouzarides T. 2007. Chromatin modifications and their function. Cell 128:693-705.
-
(2007)
Cell
, vol.128
, pp. 693-705
-
-
Kouzarides, T.1
-
89
-
-
0035282573
-
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins
-
Lachner M, O'Carroll D, Rea S, Mechtler K, Jenuwein T. 2001. Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins. Nature 410:116-120.
-
(2001)
Nature
, vol.410
, pp. 116-120
-
-
Lachner, M.1
O'Carroll, D.2
Rea, S.3
Mechtler, K.4
Jenuwein, T.5
-
90
-
-
0037672689
-
An epigenetic road map for histone lysine methylation
-
Lachner M, O'Sullivan RJ, Jenuwein T. 2003. An epigenetic road map for histone lysine methylation. J Cell Sci 116:2117-2124.
-
(2003)
J Cell Sci
, vol.116
, pp. 2117-2124
-
-
Lachner, M.1
O'Sullivan, R.J.2
Jenuwein, T.3
-
91
-
-
10744230544
-
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
Lehnertz B, Ueda Y, Derijck AAHA, Braunschweig U, Perez-Burgos L, Kubicek S, Chen T, Li E, Jenuwein T, Peters AHFM. 2003. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 13:1192-1200.
-
(2003)
Curr Biol
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.H.A.3
Braunschweig, U.4
Perez-Burgos, L.5
Kubicek, S.6
Chen, T.7
Li, E.8
Jenuwein, T.9
Peters, A.H.F.M.10
-
92
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt H, Page AW, Weier HU, Bestor TH. 1992. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71:865-873.
-
(1992)
Cell
, vol.71
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
93
-
-
0036135014
-
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
-
Liang G, Chan MF, Tomigahara Y, Tsai YC, Gonzales FA, Li E, Laird PW, Jones PA. 2002. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol Cell Biol 22:480-491.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 480-491
-
-
Liang, G.1
Chan, M.F.2
Tomigahara, Y.3
Tsai, Y.C.4
Gonzales, F.A.5
Li, E.6
Laird, P.W.7
Jones, P.A.8
-
94
-
-
80051998696
-
Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1
-
Lin W, Cao J, Liu J, Beshiri ML, Fujiwara Y, Francis J, Cherniack AD, Geisen C, Blair LP, Zou MR, Shen X, Kawamori D, Liu Z, Grisanzio C, Watanabe H, Minamishima YA, Zhang Q, Kulkarni RN, Signoretti S, Rodig SJ, Bronson R, Orkin SH, Tuck DP, Benevolenskaya EV, Meyerson M, Kaelin WG, Yan Q. 2011. Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1. Proc Natl Acad Sci USA 108:13379-13386.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 13379-13386
-
-
Lin, W.1
Cao, J.2
Liu, J.3
Beshiri, M.L.4
Fujiwara, Y.5
Francis, J.6
Cherniack, A.D.7
Geisen, C.8
Blair, L.P.9
Zou, M.R.10
Shen, X.11
Kawamori, D.12
Liu, Z.13
Grisanzio, C.14
Watanabe, H.15
Minamishima, Y.A.16
Zhang, Q.17
Kulkarni, R.N.18
Signoretti, S.19
Rodig, S.J.20
Bronson, R.21
Orkin, S.H.22
Tuck, D.P.23
Benevolenskaya, E.V.24
Meyerson, M.25
Kaelin, W.G.26
Yan, Q.27
more..
-
95
-
-
0035341465
-
Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci
-
Litt MD, Simpson M, Recillas-Targa F, Prioleau MN, Felsenfeld G. 2001. Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci. EMBO J 20:2224-2235.
-
(2001)
EMBO J
, vol.20
, pp. 2224-2235
-
-
Litt, M.D.1
Simpson, M.2
Recillas-Targa, F.3
Prioleau, M.N.4
Felsenfeld, G.5
-
96
-
-
15444379011
-
Regulation of neuron survival and death by p130 and associated chromatin modifiers
-
Liu DX, Nath N, Chellappan SP, Greene LA. 2005. Regulation of neuron survival and death by p130 and associated chromatin modifiers. Genes Dev 19:719-732.
-
(2005)
Genes Dev
, vol.19
, pp. 719-732
-
-
Liu, D.X.1
Nath, N.2
Chellappan, S.P.3
Greene, L.A.4
-
97
-
-
18744405062
-
Corepressor-dependent silencing of chromosomal regions encoding neuronal genes
-
Lunyak VV, Burgess R, Prefontaine GG, Nelson C, Sze S-H, Chenoweth J, Schwartz P, Pevzner PA, Glass C, Mandel G, Rosenfeld MG. 2002. Corepressor-dependent silencing of chromosomal regions encoding neuronal genes. Science 298:1747-1752.
-
(2002)
Science
, vol.298
, pp. 1747-1752
-
-
Lunyak, V.V.1
Burgess, R.2
Prefontaine, G.G.3
Nelson, C.4
Sze, S.-H.5
Chenoweth, J.6
Schwartz, P.7
Pevzner, P.A.8
Glass, C.9
Mandel, G.10
Rosenfeld, M.G.11
-
98
-
-
0032549001
-
Rb interacts with histone deacetylase to repress transcription
-
Luo RX, Postigo AA, Dean DC. 1998. Rb interacts with histone deacetylase to repress transcription. Cell 92:463-473.
-
(1998)
Cell
, vol.92
, pp. 463-473
-
-
Luo, R.X.1
Postigo, A.A.2
Dean, D.C.3
-
99
-
-
0038304456
-
pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer
-
Macaluso M, Cinti C, Russo G, Russo A, Giordano A. 2003. pRb2/p130-E2F4/5-HDAC1-SUV39H1-p300 and pRb2/p130-E2F4/5-HDAC1-SUV39H1-DNMT1 multimolecular complexes mediate the transcription of estrogen receptor-alpha in breast cancer. Oncogene 22:3511-3517.
-
(2003)
Oncogene
, vol.22
, pp. 3511-3517
-
-
Macaluso, M.1
Cinti, C.2
Russo, G.3
Russo, A.4
Giordano, A.5
-
100
-
-
0032484904
-
Retinoblastoma protein represses transcription by recruiting a histone deacetylase
-
Magnaghi-Jaulin L, Groisman R, Naguibneva I, Robin P, Lorain S, Le Villain JP, Troalen F, Trouche D, Harel-Bellan A. 1998. Retinoblastoma protein represses transcription by recruiting a histone deacetylase. Nature 391:601-605.
-
(1998)
Nature
, vol.391
, pp. 601-605
-
-
Magnaghi-Jaulin, L.1
Groisman, R.2
Naguibneva, I.3
Robin, P.4
Lorain, S.5
Le Villain, J.P.6
Troalen, F.7
Trouche, D.8
Harel-Bellan, A.9
-
101
-
-
0029746494
-
Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer-mediated repression
-
Maillet L, Boscheron C, Gotta M, Marcand S, Gilson E, Gasser SM. 1996. Evidence for silencing compartments within the yeast nucleus: A role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev 10:1796-1811.
-
(1996)
Genes Dev
, vol.10
, pp. 1796-1811
-
-
Maillet, L.1
Boscheron, C.2
Gotta, M.3
Marcand, S.4
Gilson, E.5
Gasser, S.M.6
-
103
-
-
0036712390
-
Evidence that Swi/Snf directly represses transcription in S. Cerevisiae
-
Martens JA, Winston F. 2002. Evidence that Swi/Snf directly represses transcription in S. Cerevisiae. Genes Dev 16:2231-2236.
-
(2002)
Genes Dev
, vol.16
, pp. 2231-2236
-
-
Martens, J.A.1
Winston, F.2
-
104
-
-
0037380161
-
Recent advances in understanding chromatin remodeling by Swi/Snf complexes
-
Martens JA, Winston F. 2003. Recent advances in understanding chromatin remodeling by Swi/Snf complexes. Curr Opin Genet Dev 13:136-142.
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 136-142
-
-
Martens, J.A.1
Winston, F.2
-
105
-
-
33645804789
-
Methylation of histone H3 mediates the association of the NuA3 histone acetyltransferase with chromatin
-
Martin DGE, Grimes DE, Baetz K, Howe L. 2006. Methylation of histone H3 mediates the association of the NuA3 histone acetyltransferase with chromatin. Mol Cell Biol 26:3018-3028.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3018-3028
-
-
Martin, D.G.E.1
Grimes, D.E.2
Baetz, K.3
Howe, L.4
-
106
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer W, Niveleau A, Walter J, Fundele R, Haaf T. 2000. Demethylation of the zygotic paternal genome. Nature 403:501-502.
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
Niveleau, A.2
Walter, J.3
Fundele, R.4
Haaf, T.5
-
107
-
-
18144419362
-
Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway
-
McCabe MT, Davis JN, Day ML. 2005. Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway. Cancer Res 65:3624-3632.
-
(2005)
Cancer Res
, vol.65
, pp. 3624-3632
-
-
McCabe, M.T.1
Davis, J.N.2
Day, M.L.3
-
108
-
-
0034056777
-
Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression
-
Melcher M, Schmid M, Aagaard L, Selenko P, Laible G, Jenuwein T. 2000. Structure-function analysis of SUV39H1 reveals a dominant role in heterochromatin organization, chromosome segregation, and mitotic progression. Mol Cell Biol 20:3728-3741.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3728-3741
-
-
Melcher, M.1
Schmid, M.2
Aagaard, L.3
Selenko, P.4
Laible, G.5
Jenuwein, T.6
-
109
-
-
40449123137
-
Cyclical DNA methylation of a transcriptionally active promoter
-
Métivier R, Gallais R, Tiffoche C, Le Péron C, Jurkowska RZ, Carmouche RP, Ibberson D, Barath P, Demay F. 2008. Cyclical DNA methylation of a transcriptionally active promoter. Nature 452:45-50.
-
(2008)
Nature
, vol.452
, pp. 45-50
-
-
Métivier, R.1
Gallais, R.2
Tiffoche, C.3
Le Péron, C.4
Jurkowska, R.Z.5
Carmouche, R.P.6
Ibberson, D.7
Barath, P.8
Demay, F.9
-
110
-
-
34247116336
-
Connections between epigenetic gene silencing and human disease
-
Moss TJ, Wallrath LL. 2007. Connections between epigenetic gene silencing and human disease. Mutat Res 618:163-174.
-
(2007)
Mutat Res
, vol.618
, pp. 163-174
-
-
Moss, T.J.1
Wallrath, L.L.2
-
111
-
-
55349095456
-
Cellular senescence: Molecular mechanisms, in vivo significance, and redox considerations
-
Muller M. 2009. Cellular senescence: Molecular mechanisms, in vivo significance, and redox considerations. Antioxid Redox Signal 11:59-98.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 59-98
-
-
Muller, M.1
-
112
-
-
0035815360
-
Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly
-
Nakayama J, Rice JC, Strahl BD, Allis CD, Grewal SI. 2001. Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly. Science 292:110-113.
-
(2001)
Science
, vol.292
, pp. 110-113
-
-
Nakayama, J.1
Rice, J.C.2
Strahl, B.D.3
Allis, C.D.4
Grewal, S.I.5
-
113
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nũnez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW. 2003. Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 113:703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nũnez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
114
-
-
33645879818
-
Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
-
Nathan D, Ingvarsdottir K, Sterner DE, Bylebyl GR, Dokmanovic M, Dorsey JA, Whelan KA, Krsmanovic M, Lane WS, Meluh PB, Johnson ES, Berger SL. 2006. Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications. Genes Dev 20:966-976.
-
(2006)
Genes Dev
, vol.20
, pp. 966-976
-
-
Nathan, D.1
Ingvarsdottir, K.2
Sterner, D.E.3
Bylebyl, G.R.4
Dokmanovic, M.5
Dorsey, J.A.6
Whelan, K.A.7
Krsmanovic, M.8
Lane, W.S.9
Meluh, P.B.10
Johnson, E.S.11
Berger, S.L.12
-
115
-
-
33748163064
-
Proline isomerization of histone H3 regulates lysine methylation and gene expression
-
Nelson CJ, Santos-Rosa H, Kouzarides T. 2006. Proline isomerization of histone H3 regulates lysine methylation and gene expression. Cell 126:905-916.
-
(2006)
Cell
, vol.126
, pp. 905-916
-
-
Nelson, C.J.1
Santos-Rosa, H.2
Kouzarides, T.3
-
116
-
-
0033119780
-
DNA methylation and chromatin modification
-
Ng HH, Bird A. 1999. DNA methylation and chromatin modification. Curr Opin Genet Dev 9:158-163.
-
(1999)
Curr Opin Genet Dev
, vol.9
, pp. 158-163
-
-
Ng, H.H.1
Bird, A.2
-
117
-
-
0037371661
-
Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter
-
Nicolas E, Roumillac C, Trouche D. 2003. Balance between acetylation and methylation of histone H3 lysine 9 on the E2F-responsive dihydrofolate reductase promoter. Mol Cell Biol 23:1614-1622.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 1614-1622
-
-
Nicolas, E.1
Roumillac, C.2
Trouche, D.3
-
118
-
-
0033571206
-
Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family
-
Nielsen AL, Ortiz JA, You J, Oulad-Abdelghani M, Khechumian R, Gansmuller A, Chambon P, Losson R. 1999. Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J 18:6385-6395.
-
(1999)
EMBO J
, vol.18
, pp. 6385-6395
-
-
Nielsen, A.L.1
Ortiz, J.A.2
You, J.3
Oulad-Abdelghani, M.4
Khechumian, R.5
Gansmuller, A.6
Chambon, P.7
Losson, R.8
-
119
-
-
0035797384
-
Rb targets histone H3 methylation and HP1 to promoters
-
Nielsen SJ, Schneider R, Bauer UM, Bannister AJ, Morrison A, O'Carroll D, Firestein R, Cleary M, Jenuwein T, Herrera RE, Kouzarides T. 2001. Rb targets histone H3 methylation and HP1 to promoters. Nature 412:561-565.
-
(2001)
Nature
, vol.412
, pp. 561-565
-
-
Nielsen, S.J.1
Schneider, R.2
Bauer, U.M.3
Bannister, A.J.4
Morrison, A.5
O'Carroll, D.6
Firestein, R.7
Cleary, M.8
Jenuwein, T.9
Herrera, R.E.10
Kouzarides, T.11
-
120
-
-
80053203114
-
The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence
-
Nijwening JH, Geutjes E-J, Bernards R, Beijersbergen RL. 2011. The histone demethylase Jarid1b (Kdm5b) is a novel component of the Rb pathway and associates with E2f-target genes in MEFs during senescence. PLoS ONE 6:e25235.
-
(2011)
PLoS ONE
, vol.6
-
-
Nijwening, J.H.1
Geutjes, E.-J.2
Bernards, R.3
Beijersbergen, R.L.4
-
121
-
-
1642326716
-
Phosphorylation of histone H3: A balancing act between chromosome condensation and transcriptional activation
-
Nowak SJ, Corces VG. 2004. Phosphorylation of histone H3: A balancing act between chromosome condensation and transcriptional activation. Trends Genet 20:214-220.
-
(2004)
Trends Genet
, vol.20
, pp. 214-220
-
-
Nowak, S.J.1
Corces, V.G.2
-
122
-
-
0034461595
-
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression
-
O'Carroll D, Scherthan H, Peters AH, Opravil S, Haynes AR, Laible G, Lebersorger A, Jerratsch M, Sattler L, Mattei MG, Denny P, Brown SD, Schweizer D, Jenuwein T. 2000. Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. Mol Cell Biol 20:9423-9433.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 9423-9433
-
-
O'Carroll, D.1
Scherthan, H.2
Peters, A.H.3
Opravil, S.4
Haynes, A.R.5
Laible, G.6
Lebersorger, A.7
Jerratsch, M.8
Sattler, L.9
Mattei, M.G.10
Denny, P.11
Brown, S.D.12
Schweizer, D.13
Jenuwein, T.14
-
123
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257.
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
124
-
-
78649506206
-
Regulation of the chlamydomonas cell cycle by a stable, chromatin-associated retinoblastoma tumor suppressor complex
-
Olson BJSC, Oberholzer M, Li Y, Zones JM, Kohli HS, Bisova K, Fang SC, Meisenhelder J, Hunter T, Umen JG. 2010. Regulation of the chlamydomonas cell cycle by a stable, chromatin-associated retinoblastoma tumor suppressor complex. Plant Cell Online 22:3331-3347.
-
(2010)
Plant Cell Online
, vol.22
, pp. 3331-3347
-
-
Olson, B.J.S.C.1
Oberholzer, M.2
Li, Y.3
Zones, J.M.4
Kohli, H.S.5
Bisova, K.6
Fang, S.C.7
Meisenhelder, J.8
Hunter, T.9
Umen, J.G.10
-
125
-
-
45449114804
-
The colorful history of active DNA demethylation
-
Ooi SKT, Bestor TH. 2008. The colorful history of active DNA demethylation. Cell 133:1145-1148.
-
(2008)
Cell
, vol.133
, pp. 1145-1148
-
-
Ooi, S.K.T.1
Bestor, T.H.2
-
126
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald J, Engemann S, Lane N, Mayer W, Olek A, Fundele R, Dean W, Reik W, Walter J. 2000. Active demethylation of the paternal genome in the mouse zygote. Curr Biol 10:475-478.
-
(2000)
Curr Biol
, vol.10
, pp. 475-478
-
-
Oswald, J.1
Engemann, S.2
Lane, N.3
Mayer, W.4
Olek, A.5
Fundele, R.6
Dean, W.7
Reik, W.8
Walter, J.9
-
127
-
-
46149100720
-
The global histone modification pattern correlates with cancer recurrence and overall survival in gastric adenocarcinoma
-
Park YS, Jin MY, Kim YJ, Yook JH, Kim BS, Jang SJ. 2008. The global histone modification pattern correlates with cancer recurrence and overall survival in gastric adenocarcinoma. Ann Surg Oncol 15:1968-1976.
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 1968-1976
-
-
Park, Y.S.1
Jin, M.Y.2
Kim, Y.J.3
Yook, J.H.4
Kim, B.S.5
Jang, S.J.6
-
128
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schöfer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A, Opravil S, Doyle M, Sibilia M, Jenuwein T. 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107:323-337.
-
(2001)
Cell
, vol.107
, pp. 323-337
-
-
Peters, A.H.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
Sauer, S.5
Schöfer, C.6
Weipoltshammer, K.7
Pagani, M.8
Lachner, M.9
Kohlmaier, A.10
Opravil, S.11
Doyle, M.12
Sibilia, M.13
Jenuwein, T.14
-
129
-
-
0036338205
-
Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin
-
Peters AHFM, Mermoud JE, O'Carroll D, Pagani M, Schweizer D, Brockdorff N, Jenuwein T. 2002. Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin. Nat Genet 30:77-80.
-
(2002)
Nat Genet
, vol.30
, pp. 77-80
-
-
Peters, A.H.F.M.1
Mermoud, J.E.2
O'Carroll, D.3
Pagani, M.4
Schweizer, D.5
Brockdorff, N.6
Jenuwein, T.7
-
130
-
-
0029586756
-
The centromere: Hub of chromosomal activities
-
Pluta AF, Mackay AM, Ainsztein AM, Goldberg IG, Earnshaw WC. 1995. The centromere: Hub of chromosomal activities. Science 270:1591-1594.
-
(1995)
Science
, vol.270
, pp. 1591-1594
-
-
Pluta, A.F.1
Mackay, A.M.2
Ainsztein, A.M.3
Goldberg, I.G.4
Earnshaw, W.C.5
-
131
-
-
0028791330
-
Mechanism of protein access to specific DNA sequences in chromatin: A dynamic equilibrium model for gene regulation
-
Polach KJ, Widom J. 1995. Mechanism of protein access to specific DNA sequences in chromatin: A dynamic equilibrium model for gene regulation. J Mol Biol 254:130-149.
-
(1995)
J Mol Biol
, vol.254
, pp. 130-149
-
-
Polach, K.J.1
Widom, J.2
-
132
-
-
0032722062
-
Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation
-
Pradhan S, Bacolla A, Wells RD, Roberts RJ. 1999. Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem 274:33002-33010.
-
(1999)
J Biol Chem
, vol.274
, pp. 33002-33010
-
-
Pradhan, S.1
Bacolla, A.2
Wells, R.D.3
Roberts, R.J.4
-
133
-
-
38149019842
-
Pericentric heterochromatin: Dynamic organization during early development in mammals
-
Probst AV, Almouzni G. 2008. Pericentric heterochromatin: Dynamic organization during early development in mammals. Differentiation 76:15-23.
-
(2008)
Differentiation
, vol.76
, pp. 15-23
-
-
Probst, A.V.1
Almouzni, G.2
-
135
-
-
57649196594
-
DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45
-
Rai K, Huggins IJ, James SR, Karpf AR, Jones DA, Cairns BR. 2008. DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45. Cell 135:1201-1212.
-
(2008)
Cell
, vol.135
, pp. 1201-1212
-
-
Rai, K.1
Huggins, I.J.2
James, S.R.3
Karpf, A.R.4
Jones, D.A.5
Cairns, B.R.6
-
136
-
-
0032168678
-
CpG methylation, chromatin structure and gene silencing-a three-way connection
-
Razin A. 1998. CpG methylation, chromatin structure and gene silencing-a three-way connection. EMBO J 17:4905-4908.
-
(1998)
EMBO J
, vol.17
, pp. 4905-4908
-
-
Razin, A.1
-
137
-
-
34249279527
-
Stability and flexibility of epigenetic gene regulation in mammalian development
-
Reik W. 2007. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447:425-432.
-
(2007)
Nature
, vol.447
, pp. 425-432
-
-
Reik, W.1
-
138
-
-
17744391429
-
Co-evolution of X-chromosome inactivation and imprinting in mammals
-
Reik W, Lewis A. 2005. Co-evolution of X-chromosome inactivation and imprinting in mammals. Nat Rev Genet 6:403-410.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 403-410
-
-
Reik, W.1
Lewis, A.2
-
139
-
-
0023196308
-
Genomic imprinting determines methylation of parental alleles in transgenic mice
-
Reik W, Collick A, Norris ML, Barton SC, Surani MA. 1987. Genomic imprinting determines methylation of parental alleles in transgenic mice. Nature 328:248-251.
-
(1987)
Nature
, vol.328
, pp. 248-251
-
-
Reik, W.1
Collick, A.2
Norris, M.L.3
Barton, S.C.4
Surani, M.A.5
-
141
-
-
0033919595
-
DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters
-
Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP. 2000. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters. Nat Genet 25:338-342.
-
(2000)
Nat Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
Ait-Si-Ali, S.2
Yokochi, T.3
Wade, P.A.4
Jones, P.L.5
Wolffe, A.P.6
-
142
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos F. 2002. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev Biol 241:172-182.
-
(2002)
Dev Biol
, vol.241
, pp. 172-182
-
-
Santos, F.1
-
143
-
-
38349100549
-
Epigenetic events in mammalian germ-cell development: Reprogramming and beyond
-
Sasaki H, Matsui Y. 2008. Epigenetic events in mammalian germ-cell development: Reprogramming and beyond. Nat Rev Genet 9:129-140.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 129-140
-
-
Sasaki, H.1
Matsui, Y.2
-
144
-
-
27144535374
-
Trapped in action: Direct visualization of DNA methyltransferase activity in living cells
-
Schermelleh L, Spada F, Easwaran HP, Zolghadr K, Margot JB, Cardoso MC, Leonhardt H. 2005. Trapped in action: Direct visualization of DNA methyltransferase activity in living cells. Nat Methods 2:751-756.
-
(2005)
Nat Methods
, vol.2
, pp. 751-756
-
-
Schermelleh, L.1
Spada, F.2
Easwaran, H.P.3
Zolghadr, K.4
Margot, J.B.5
Cardoso, M.C.6
Leonhardt, H.7
-
145
-
-
34547842515
-
Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation
-
Schermelleh L, Haemmer A, Spada F, Rösing N, Meilinger D, Rothbauer U, Cardoso C, Leonhardt H. 2007. Dynamics of Dnmt1 interaction with the replication machinery and its role in postreplicative maintenance of DNA methylation. Nucleic Acids Res 35:4301-4312.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 4301-4312
-
-
Schermelleh, L.1
Haemmer, A.2
Spada, F.3
Rösing, N.4
Meilinger, D.5
Rothbauer, U.6
Cardoso, C.7
Leonhardt, H.8
-
146
-
-
2642542643
-
A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin
-
Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R, Reuter G, Reinberg D, Jenuwein T. 2004. A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18:1251-1262.
-
(2004)
Genes Dev
, vol.18
, pp. 1251-1262
-
-
Schotta, G.1
Lachner, M.2
Sarma, K.3
Ebert, A.4
Sengupta, R.5
Reuter, G.6
Reinberg, D.7
Jenuwein, T.8
-
147
-
-
80052586181
-
Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
-
Sdek P, Zhao P, Wang Y, Huang CJ, Ko CY, Butler PC, Weiss JN, MacLellan WR. 2011. Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes. J Cell Biol 194:407-423.
-
(2011)
J Cell Biol
, vol.194
, pp. 407-423
-
-
Sdek, P.1
Zhao, P.2
Wang, Y.3
Huang, C.J.4
Ko, C.Y.5
Butler, P.C.6
Weiss, J.N.7
MacLellan, W.R.8
-
148
-
-
21744457108
-
Global histone modification patterns predict risk of prostate cancer recurrence
-
Seligson DB, Horvath S, Shi T, Yu H, Tze S, Grunstein M, Kurdistani SK. 2005. Global histone modification patterns predict risk of prostate cancer recurrence. Nature 435:1262-1266.
-
(2005)
Nature
, vol.435
, pp. 1262-1266
-
-
Seligson, D.B.1
Horvath, S.2
Shi, T.3
Yu, H.4
Tze, S.5
Grunstein, M.6
Kurdistani, S.K.7
-
149
-
-
84857767977
-
Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases
-
Selvakumar T, Gjidoda A, Hovde SL, Henry RW. 2012. Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases. J Biol Chem 287:7039-7050.
-
(2012)
J Biol Chem
, vol.287
, pp. 7039-7050
-
-
Selvakumar, T.1
Gjidoda, A.2
Hovde, S.L.3
Henry, R.W.4
-
150
-
-
33846025127
-
Dynamic regulation of histone lysine methylation by demethylases
-
Shi Y, Whetstine JR. 2007. Dynamic regulation of histone lysine methylation by demethylases. Mol Cell 25:1-14.
-
(2007)
Mol Cell
, vol.25
, pp. 1-14
-
-
Shi, Y.1
Whetstine, J.R.2
-
151
-
-
33746324216
-
Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
-
Shilatifard A. 2006. Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression. Annu Rev Biochem 75:243-269.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 243-269
-
-
Shilatifard, A.1
-
152
-
-
32444434989
-
Histone H4-K16 acetylation controls chromatin structure and protein interactions
-
Shogren-Knaak M, Ishii H, Sun J-M, Pazin MJ, Davie JR, Peterson CL. 2006. Histone H4-K16 acetylation controls chromatin structure and protein interactions. Science 311:844-847.
-
(2006)
Science
, vol.311
, pp. 844-847
-
-
Shogren-Knaak, M.1
Ishii, H.2
Sun, J.-M.3
Pazin, M.J.4
Davie, J.R.5
Peterson, C.L.6
-
153
-
-
0030857774
-
Telomerase and telomere-binding proteins: Controlling the endgame
-
Shore D. 1997. Telomerase and telomere-binding proteins: Controlling the endgame. Trends Biochem Sci 22:233-235.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 233-235
-
-
Shore, D.1
-
154
-
-
0033564902
-
DNA methylation
-
Singal R, Ginder GD. 1999. DNA methylation. Blood 93:4059-4070.
-
(1999)
Blood
, vol.93
, pp. 4059-4070
-
-
Singal, R.1
Ginder, G.D.2
-
155
-
-
0034051227
-
Acetylation of histones and transcription-related factors
-
Sterner DE, Berger SL. 2000. Acetylation of histones and transcription-related factors. Microbiol Mol Biol Rev 64:435-459.
-
(2000)
Microbiol Mol Biol Rev
, vol.64
, pp. 435-459
-
-
Sterner, D.E.1
Berger, S.L.2
-
156
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl BD, Allis CD. 2000. The language of covalent histone modifications. Nature 403:41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
157
-
-
1542346419
-
Chromatin remodeling by RNA polymerases
-
Studitsky VM, Walter W, Kireeva M, Kashlev M, Felsenfeld G. 2004. Chromatin remodeling by RNA polymerases. Trends Biochem Sci 29:127-135.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 127-135
-
-
Studitsky, V.M.1
Walter, W.2
Kireeva, M.3
Kashlev, M.4
Felsenfeld, G.5
-
158
-
-
33847076246
-
Genetic and epigenetic regulators of pluripotency
-
Surani MA, Hayashi K, Hajkova P. 2007. Genetic and epigenetic regulators of pluripotency. Cell 128:747-762.
-
(2007)
Cell
, vol.128
, pp. 747-762
-
-
Surani, M.A.1
Hayashi, K.2
Hajkova, P.3
-
159
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai D, Jones PA. 2002. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci USA 99:3740-3745.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
160
-
-
67449091253
-
Chromosome segregation machinery and cancer
-
Tanaka K, Hirota T. 2009. Chromosome segregation machinery and cancer. Cancer Sci 100:1158-1165.
-
(2009)
Cancer Sci
, vol.100
, pp. 1158-1165
-
-
Tanaka, K.1
Hirota, T.2
-
161
-
-
3042848975
-
Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A
-
Tonini T, Bagella L, D'Andrilli G, Claudio PP, Giordano A. 2004. Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A. Oncogene 23:4930-4937.
-
(2004)
Oncogene
, vol.23
, pp. 4930-4937
-
-
Tonini, T.1
Bagella, L.2
D'Andrilli, G.3
Claudio, P.P.4
Giordano, A.5
-
162
-
-
0030867899
-
RB and hbrm cooperate to repress the activation functions of E2F1
-
Trouche D, Le Chalony C, Muchardt C, Yaniv M, Kouzarides T. 1997. RB and hbrm cooperate to repress the activation functions of E2F1. Proc Natl Acad Sci USA 94:11268-11273.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 11268-11273
-
-
Trouche, D.1
Le Chalony, C.2
Muchardt, C.3
Yaniv, M.4
Kouzarides, T.5
-
163
-
-
58149329023
-
Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer
-
van den Broeck A, Brambilla E, Moro-Sibilot D, Lantuejoul S, Brambilla C, Eymin B, Khochbin S, Gazzeri S. 2008. Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin Cancer Res 14:7237-7245.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7237-7245
-
-
van den Broeck, A.1
Brambilla, E.2
Moro-Sibilot, D.3
Lantuejoul, S.4
Brambilla, C.5
Eymin, B.6
Khochbin, S.7
Gazzeri, S.8
-
164
-
-
0036965325
-
From epigenesis to epigenetics: The case of C.H. Waddington
-
van Speybroeck L. 2002. From epigenesis to epigenetics: The case of C.H. Waddington. Ann N Y Acad Sci 981:61-81.
-
(2002)
Ann N Y Acad Sci
, vol.981
, pp. 61-81
-
-
van Speybroeck, L.1
-
165
-
-
0034811677
-
Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase
-
Vandel L, Nicolas E, Vaute O, Ferreira R, Ait-Si-Ali S, Trouche D. 2001. Transcriptional repression by the retinoblastoma protein through the recruitment of a histone methyltransferase. Mol Cell Biol 21:6484-6494.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6484-6494
-
-
Vandel, L.1
Nicolas, E.2
Vaute, O.3
Ferreira, R.4
Ait-Si-Ali, S.5
Trouche, D.6
-
166
-
-
33646550204
-
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
-
Vaquero A, Scher MB, Lee DH, Sutton A, Cheng H-L, Alt FW, Serrano L, Sternglanz R, Reinberg D. 2006. SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev 20:1256-1261.
-
(2006)
Genes Dev
, vol.20
, pp. 1256-1261
-
-
Vaquero, A.1
Scher, M.B.2
Lee, D.H.3
Sutton, A.4
Cheng, H.-L.5
Alt, F.W.6
Serrano, L.7
Sternglanz, R.8
Reinberg, D.9
-
167
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
Walsh CP, Chaillet JR, Bestor TH. 1998. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet 20:116-117.
-
(1998)
Nat Genet
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
168
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang H, Wang L, Erdjument-Bromage H, Vidal M, Tempst P, Jones RS, Zhang Y. 2004. Role of histone H2A ubiquitination in Polycomb silencing. Nature 431:873-878.
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
Wang, L.2
Erdjument-Bromage, H.3
Vidal, M.4
Tempst, P.5
Jones, R.S.6
Zhang, Y.7
-
169
-
-
33744781568
-
Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage
-
Wang H, Zhai L, Xu J, Joo H-Y, Jackson S, Erdjument-Bromage H, Tempst P, Xiong Y, Zhang Y. 2006. Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol Cell 22:383-394.
-
(2006)
Mol Cell
, vol.22
, pp. 383-394
-
-
Wang, H.1
Zhai, L.2
Xu, J.3
Joo, H.-Y.4
Jackson, S.5
Erdjument-Bromage, H.6
Tempst, P.7
Xiong, Y.8
Zhang, Y.9
-
170
-
-
0020068934
-
Studies of X chromosome DNA methylation in normal human cells
-
Wolf SF, Migeon BR. 1982. Studies of X chromosome DNA methylation in normal human cells. Nature 295:667-671.
-
(1982)
Nature
, vol.295
, pp. 667-671
-
-
Wolf, S.F.1
Migeon, B.R.2
-
171
-
-
0029997378
-
Targeting chromatin disruption: Transcription regulators that acetylate histones
-
Wolffe AP, Pruss D. 1996. Targeting chromatin disruption: Transcription regulators that acetylate histones. Cell 84:817-819.
-
(1996)
Cell
, vol.84
, pp. 817-819
-
-
Wolffe, A.P.1
Pruss, D.2
-
172
-
-
0023176797
-
Kinetic and catalytic mechanism of HhaI methyltransferase
-
Wu JC, Santi DV. 1987. Kinetic and catalytic mechanism of HhaI methyltransferase. J Biol Chem 262:4778-4786.
-
(1987)
J Biol Chem
, vol.262
, pp. 4778-4786
-
-
Wu, J.C.1
Santi, D.V.2
-
173
-
-
33745839365
-
A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling
-
Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait B, Badenhorst P, Wu C, Allis CD. 2006. A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling. Nature 442:86-90.
-
(2006)
Nature
, vol.442
, pp. 86-90
-
-
Wysocka, J.1
Swigut, T.2
Xiao, H.3
Milne, T.A.4
Kwon, S.Y.5
Landry, J.6
Kauer, M.7
Tackett, A.J.8
Chait, B.9
Badenhorst, P.10
Wu, C.11
Allis, C.D.12
-
174
-
-
0030840954
-
Cytosine methylation and the ecology of intragenomic parasites
-
Yoder JA, Walsh CP, Bestor TH. 1997. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet 13:335-340.
-
(1997)
Trends Genet
, vol.13
, pp. 335-340
-
-
Yoder, J.A.1
Walsh, C.P.2
Bestor, T.H.3
-
175
-
-
0035883954
-
Transcription regulation by histone methylation: Interplay between different covalent modifications of the core histone tails
-
Zhang Y, Reinberg D. 2001. Transcription regulation by histone methylation: Interplay between different covalent modifications of the core histone tails. Genes Dev 15:2343-2360.
-
(2001)
Genes Dev
, vol.15
, pp. 2343-2360
-
-
Zhang, Y.1
Reinberg, D.2
|