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Volumn 93, Issue 12, 1999, Pages 4059-4070

DNA methylation

Author keywords

[No Author keywords available]

Indexed keywords

CAENORHABDITIS ELEGANS; CONFORMATIONAL TRANSITION; DNA DETERMINATION; DNA METHYLATION; DROSOPHILA MELANOGASTER; GENE EXPRESSION REGULATION; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; REVIEW; SACCHAROMYCES CEREVISIAE;

EID: 0033564902     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v93.12.4059     Document Type: Review
Times cited : (437)

References (140)
  • 1
    • 0027353343 scopus 로고
    • A chronicle of DNA methylation(1948-1975)
    • Weissbach A: A chronicle of DNA methylation(1948-1975). EXS 64:1, 1993
    • (1993) EXS , vol.64 , pp. 1
    • Weissbach, A.1
  • 2
    • 0020476276 scopus 로고
    • The absence of detectable methylated bases in Drosophila melanogaster DNA
    • Urieli-Shoval S, Gruenbaum Y, Sedat J, Razin A: The absence of detectable methylated bases in Drosophila melanogaster DNA. FEBS Lett 146:148, 1982
    • (1982) FEBS Lett , vol.146 , pp. 148
    • Urieli-Shoval, S.1    Gruenbaum, Y.2    Sedat, J.3    Razin, A.4
  • 3
    • 0021132637 scopus 로고
    • 5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA
    • Proffitt JH, Davie JR, Swinton D, Hattman S: 5-Methylcytosine is not detectable in Saccharomyces cerevisiae DNA. Mol Cell Biol 4:985, 1984
    • (1984) Mol Cell Biol , vol.4 , pp. 985
    • Proffitt, J.H.1    Davie, J.R.2    Swinton, D.3    Hattman, S.4
  • 4
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li E, Bestor TH, Jaenisch R: Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69:915, 1992
    • (1992) Cell , vol.69 , pp. 915
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 5
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder JA, Walsh CP, Bestor TH: Cytosine methylation and the ecology of intragenomic parasites. Trends Genet 13:335, 1997
    • (1997) Trends Genet , vol.13 , pp. 335
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 7
  • 8
    • 0031467130 scopus 로고    scopus 로고
    • X-chromosome inactivation in mammals
    • Heard E, Clerc P, Avner P: X-chromosome inactivation in mammals. Annu Rev Genet 31:571, 1997
    • (1997) Annu Rev Genet , vol.31 , pp. 571
    • Heard, E.1    Clerc, P.2    Avner, P.3
  • 9
    • 0022540321 scopus 로고
    • CpG-rich islands and the function of DNA methylation
    • Bird AP: CpG-rich islands and the function of DNA methylation. Nature 321:209, 1986
    • (1986) Nature , vol.321 , pp. 209
    • Bird, A.P.1
  • 10
    • 0027141519 scopus 로고
    • Number of CpG islands and genes in human and mouse
    • Antequera F, Bird A: Number of CpG islands and genes in human and mouse. Proc Natl Acad Sci USA 90:11995, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 11995
    • Antequera, F.1    Bird, A.2
  • 11
    • 0027342643 scopus 로고
    • CpG islands
    • Antequera F, Bird A: CpG islands. EXS 64:169, 1993
    • (1993) EXS , vol.64 , pp. 169
    • Antequera, F.1    Bird, A.2
  • 12
    • 0028940587 scopus 로고
    • Gene number, noise reduction and biological complexity
    • Bird AP: Gene number, noise reduction and biological complexity. Trends Genet 11:94, 1995
    • (1995) Trends Genet , vol.11 , pp. 94
    • Bird, A.P.1
  • 13
    • 0025266610 scopus 로고
    • Alternative chromatin structure at CpG islands
    • Tazi J, Bird A: Alternative chromatin structure at CpG islands. Cell 60:909, 1990
    • (1990) Cell , vol.60 , pp. 909
    • Tazi, J.1    Bird, A.2
  • 15
    • 0030846298 scopus 로고    scopus 로고
    • Tying it all together: Epigenetics, genetics, cell cycle, and cancer
    • Baylin SB: Tying it all together: Epigenetics, genetics, cell cycle, and cancer. Science 277:1948, 1997
    • (1997) Science , vol.277 , pp. 1948
    • Baylin, S.B.1
  • 16
    • 0026653420 scopus 로고
    • The essentials of DNA methylation
    • Bird A: The essentials of DNA methylation. Cell 70:5, 1992
    • (1992) Cell , vol.70 , pp. 5
    • Bird, A.1
  • 17
    • 0024281345 scopus 로고
    • DNA methylation and gene activity
    • Cedar H: DNA methylation and gene activity. Cell 53:3, 1988
    • (1988) Cell , vol.53 , pp. 3
    • Cedar, H.1
  • 19
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor T, Laudano A, Mattaliano R, Ingram V: Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 203:971, 1988
    • (1988) J Mol Biol , vol.203 , pp. 971
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 21
    • 0029049872 scopus 로고
    • Methylation of slipped duplexes, snap-backs and cruciforms by human DNA(cytosine-5)methyltransferase
    • Laayoun A, Smith SS: Methylation of slipped duplexes, snap-backs and cruciforms by human DNA(cytosine-5)methyltransferase. Nucleic Acids Res 23:1584, 1995
    • (1995) Nucleic Acids Res , vol.23 , pp. 1584
    • Laayoun, A.1    Smith, S.S.2
  • 22
    • 0029127302 scopus 로고
    • 5-Methyl-2′-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation
    • Christman JK, Sheikhnejad G, Marasco CJ, Sufrin JR: 5-Methyl-2′-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. Proc the Natl Acad Sci USA 92:7347, 1995
    • (1995) Proc the Natl Acad Sci USA , vol.92 , pp. 7347
    • Christman, J.K.1    Sheikhnejad, G.2    Marasco, C.J.3    Sufrin, J.R.4
  • 23
    • 0031580212 scopus 로고    scopus 로고
    • Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase
    • Tollefsbol TO, Hutchison CA 3rd: Control of methylation spreading in synthetic DNA sequences by the murine DNA methyltransferase. J Mol Biol 269:494, 1997
    • (1997) J Mol Biol , vol.269 , pp. 494
    • Tollefsbol, T.O.1    Hutchison C.A. III2
  • 24
    • 0029962499 scopus 로고    scopus 로고
    • New 5′ regions of the murine and human genes for DNA (cytosine-5)-methyltransferase
    • Yoder JA, Yen RWC, Vertino PM, Bester TH, Baylin SB: New 5′ regions of the murine and human genes for DNA (cytosine-5)-methyltransferase. J Biol Chem 271:31092, 1996
    • (1996) J Biol Chem , vol.271 , pp. 31092
    • Yoder, J.A.1    Yen, R.W.C.2    Vertino, P.M.3    Bester, T.H.4    Baylin, S.B.5
  • 27
    • 0032102949 scopus 로고    scopus 로고
    • Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells
    • Okano M, Xie S, Li E: Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells. Nucleic Acids Res 26:2536, 1998
    • (1998) Nucleic Acids Res , vol.26 , pp. 2536
    • Okano, M.1    Xie, S.2    Li, E.3
  • 28
    • 0031964577 scopus 로고    scopus 로고
    • A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast
    • Yoder JA, Bestor TH: A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. Hum Mol Genet 7:279, 1998
    • (1998) Hum Mol Genet , vol.7 , pp. 279
    • Yoder, J.A.1    Bestor, T.H.2
  • 29
    • 0017841507 scopus 로고
    • Use of restriction enzymes to study eukaryotic DNA methylation: 1. The methylation pattern in ribosomal DNA from Xenopus laevis
    • Bird AP, Southern EM: Use of restriction enzymes to study eukaryotic DNA methylation: 1. The methylation pattern in ribosomal DNA from Xenopus laevis. J Mol Biol 118:27, 1978
    • (1978) J Mol Biol , vol.118 , pp. 27
    • Bird, A.P.1    Southern, E.M.2
  • 30
    • 0018171799 scopus 로고
    • MspI, an isoschizomer of hpaII which cleaves both unmethylated and methylated hpaII sites
    • Waalwijk C, Flavell RA: MspI, an isoschizomer of hpaII which cleaves both unmethylated and methylated hpaII sites. Nucleic Acids Res 5:3231, 1978
    • (1978) Nucleic Acids Res , vol.5 , pp. 3231
    • Waalwijk, C.1    Flavell, R.A.2
  • 31
    • 0018774697 scopus 로고
    • Specific DNA methylation sites in the vicinity of the chicken beta-globin genes
    • McGhee JD, Ginder GD: Specific DNA methylation sites in the vicinity of the chicken beta-globin genes. Nature 280:419, 1979
    • (1979) Nature , vol.280 , pp. 419
    • McGhee, J.D.1    Ginder, G.D.2
  • 32
    • 0025031568 scopus 로고
    • Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation
    • Singer-Sam J, Grant M, LeBon JM, Okuyama K, Chapman V, Monk M, Riggs AD: Use of a HpaII-polymerase chain reaction assay to study DNA methylation in the Pgk-1 CpG island of mouse embryos at the time of X-chromosome inactivation. Mol Cell Biol 10:4987, 1990
    • (1990) Mol Cell Biol , vol.10 , pp. 4987
    • Singer-Sam, J.1    Grant, M.2    LeBon, J.M.3    Okuyama, K.4    Chapman, V.5    Monk, M.6    Riggs, A.D.7
  • 35
    • 0018846636 scopus 로고
    • Sequencing end-labeled DNA with base-specific chemical cleavages
    • Maxam AM, Gilbert W: Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol 65:499, 1980
    • (1980) Methods Enzymol , vol.65 , pp. 499
    • Maxam, A.M.1    Gilbert, W.2
  • 38
    • 0030738231 scopus 로고    scopus 로고
    • Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE)
    • Gonzalgo ML, Jones PA: Rapid quantitation of methylation differences at specific sites using methylation-sensitive single nucleotide primer extension (Ms-SNuPE). Nucleic Acids Res 25:2529, 1997
    • (1997) Nucleic Acids Res , vol.25 , pp. 2529
    • Gonzalgo, M.L.1    Jones, P.A.2
  • 39
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: A sensitive and quantitative DNA methylation assay
    • Xiong Z, Laird PW: COBRA: A sensitive and quantitative DNA methylation assay. Nucleic Acids Res 25:2532, 1997
    • (1997) Nucleic Acids Res , vol.25 , pp. 2532
    • Xiong, Z.1    Laird, P.W.2
  • 40
    • 0016692220 scopus 로고
    • X inactivation, differentiation, and DNA methylation
    • Riggs AD: X inactivation, differentiation, and DNA methylation. Cytogenet Cell Genet 14:9, 1975
    • (1975) Cytogenet Cell Genet , vol.14 , pp. 9
    • Riggs, A.D.1
  • 41
    • 0016439429 scopus 로고
    • DNA modification mechanisms and gene activity during development
    • Holliday R, Pugh JE: DNA modification mechanisms and gene activity during development. Science 187:226, 1975
    • (1975) Science , vol.187 , pp. 226
    • Holliday, R.1    Pugh, J.E.2
  • 43
    • 0019194794 scopus 로고
    • Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes
    • Shen CK, Maniatis T: Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes. Proc Natl Acad Sci USA 77:6634, 1980
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 6634
    • Shen, C.K.1    Maniatis, T.2
  • 44
    • 0018905582 scopus 로고
    • DNA methylation in the human gamma delta beta-globin locus in erythroid and nonerythroid tissues
    • van der Ploeg LH, Flavell RA: DNA methylation in the human gamma delta beta-globin locus in erythroid and nonerythroid tissues. Cell 19:947, 1980
    • (1980) Cell , vol.19 , pp. 947
    • Van Der Ploeg, L.H.1    Flavell, R.A.2
  • 45
    • 0019318994 scopus 로고
    • DNA methylation and gene function
    • Razin A, Riggs AD: DNA methylation and gene function. Science 210:604, 1980
    • (1980) Science , vol.210 , pp. 604
    • Razin, A.1    Riggs, A.D.2
  • 46
    • 0025945632 scopus 로고
    • DNA methylation and gene expression
    • Razin A, Cedar H: DNA methylation and gene expression. Microbiol Rev 55:451, 1991
    • (1991) Microbiol Rev , vol.55 , pp. 451
    • Razin, A.1    Cedar, H.2
  • 47
    • 0027535235 scopus 로고
    • Effects of DNA methylation on DNA-binding proteins and gene expression
    • Tate PH, Bird AP: Effects of DNA methylation on DNA-binding proteins and gene expression. Curr Opin Genet Dev 3:226, 1993
    • (1993) Curr Opin Genet Dev , vol.3 , pp. 226
    • Tate, P.H.1    Bird, A.P.2
  • 48
    • 0030885667 scopus 로고    scopus 로고
    • DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa
    • Rountree MR, Selker EU: DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa. Genes Dev 11:2383, 1997
    • (1997) Genes Dev , vol.11 , pp. 2383
    • Rountree, M.R.1    Selker, E.U.2
  • 49
    • 0024342686 scopus 로고
    • Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs
    • Meehan RR, Lewis JD, McKay S, Kleiner EL, Bird AP: Identification of a mammalian protein that binds specifically to DNA containing methylated CpGs. Cell 58:499, 1989
    • (1989) Cell , vol.58 , pp. 499
    • Meehan, R.R.1    Lewis, J.D.2    McKay, S.3    Kleiner, E.L.4    Bird, A.P.5
  • 50
    • 0025975985 scopus 로고
    • DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein
    • Boyes J, Bird A: DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein. Cell 64:1123, 1991
    • (1991) Cell , vol.64 , pp. 1123
    • Boyes, J.1    Bird, A.2
  • 51
    • 0026583975 scopus 로고
    • Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein
    • Boyes J, Bird A: Repression of genes by DNA methylation depends on CpG density and promoter strength: Evidence for involvement of a methyl-CpG binding protein. EMBO J 11:327, 1992
    • (1992) EMBO J , vol.11 , pp. 327
    • Boyes, J.1    Bird, A.2
  • 52
    • 0031459894 scopus 로고    scopus 로고
    • Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells
    • Singal R, Ferris R, Little JA, Wang SZ, Cinder GD: Methylation of the minimal promoter of an embryonic globin gene silences transcription in primary erythroid cells. Proc Natl Acad Sci USA 94:13724, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 13724
    • Singal, R.1    Ferris, R.2    Little, J.A.3    Wang, S.Z.4    Cinder, G.D.5
  • 53
    • 0021203873 scopus 로고
    • Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate
    • Ginder GD, Whitters MJ, Pohlman JK: Activation of a chicken embryonic globin gene in adult erythroid cells by 5-azacytidine and sodium butyrate. Proc Natl Acad Sci USA 81:3954, 1984
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3954
    • Ginder, G.D.1    Whitters, M.J.2    Pohlman, J.K.3
  • 54
    • 0023709306 scopus 로고
    • Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells
    • Burns LJ, Glauber JG, Ginder GD: Butyrate induces selective transcriptional activation of a hypomethylated embryonic globin gene in adult erythroid cells. Blood 72:1536, 1988
    • (1988) Blood , vol.72 , pp. 1536
    • Burns, L.J.1    Glauber, J.G.2    Ginder, G.D.3
  • 55
    • 0028091804 scopus 로고
    • 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene
    • Zeleznik-Le NJ, Harden AM, Rowley JD: 11q23 translocations split the "AT-hook" cruciform DNA-binding region and the transcriptional repression domain from the activation domain of the mixed-lineage leukemia (MLL) gene. Proc Natl Acad Sci USA 91:10610, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10610
    • Zeleznik-Le, N.J.1    Harden, A.M.2    Rowley, J.D.3
  • 57
    • 0030977310 scopus 로고    scopus 로고
    • A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins
    • Cross SH, Meehan RR, Nan X, Bird A: A component of the transcriptional repressor MeCP1 shares a motif with DNA methyltransferase and HRX proteins. Nat Genet 16:256, 1997
    • (1997) Nat Genet , vol.16 , pp. 256
    • Cross, S.H.1    Meehan, R.R.2    Nan, X.3    Bird, A.4
  • 59
    • 0030071685 scopus 로고    scopus 로고
    • The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse
    • Tate P, Skarnes W, Bird A: The methyl-CpG binding protein MeCP2 is essential for embryonic development in the mouse. Nat Genet 12:205, 1996
    • (1996) Nat Genet , vol.12 , pp. 205
    • Tate, P.1    Skarnes, W.2    Bird, A.3
  • 60
    • 0342437491 scopus 로고    scopus 로고
    • MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin
    • Nan X, Campoy FJ, Bird A: MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin. Cell 88:471, 1997
    • (1997) Cell , vol.88 , pp. 471
    • Nan, X.1    Campoy, F.J.2    Bird, A.3
  • 61
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-Cpg-binding protein Mecp2 involves a histone deacetylase complex
    • Nan XS, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A: Transcriptional repression by the methyl-Cpg-binding protein Mecp2 involves a histone deacetylase complex. Nature 393:386, 1998
    • (1998) Nature , vol.393 , pp. 386
    • Nan, X.S.1    Ng, H.H.2    Johnson, C.A.3    Laherty, C.D.4    Turner, B.M.5    Eisenman, R.N.6    Bird, A.7
  • 63
    • 0030710153 scopus 로고    scopus 로고
    • How does DNA methylation repress transcription?
    • Kass SU, Pruss D, Wolffe AP: How does DNA methylation repress transcription? Trends Genet 13:444, 1997
    • (1997) Trends Genet , vol.13 , pp. 444
    • Kass, S.U.1    Pruss, D.2    Wolffe, A.P.3
  • 64
    • 0022545498 scopus 로고
    • DNA methylation affects the formation of active chromatin
    • Keshet I, Lieman-Hurwitz J, Cedar H: DNA methylation affects the formation of active chromatin. Cell 44:535, 1986
    • (1986) Cell , vol.44 , pp. 535
    • Keshet, I.1    Lieman-Hurwitz, J.2    Cedar, H.3
  • 65
    • 0031104930 scopus 로고    scopus 로고
    • DNA methylation directs a time-dependent repression of transcription initiation
    • Kass SU, Landsberger N, Wolffe AP: DNA methylation directs a time-dependent repression of transcription initiation. Curr Biol 7:157, 1997
    • (1997) Curr Biol , vol.7 , pp. 157
    • Kass, S.U.1    Landsberger, N.2    Wolffe, A.P.3
  • 66
    • 0031149162 scopus 로고    scopus 로고
    • DNA methylation: A molecular lock
    • Siegfried Z, Cedar H: DNA methylation: A molecular lock. Curr Biol 7:R305, 1997
    • (1997) Curr Biol , vol.7
    • Siegfried, Z.1    Cedar, H.2
  • 68
    • 0024316405 scopus 로고
    • Developmental regulation of hypomethylation of delta-crystallin genes in chicken embryo lens cells
    • Sullivan CH, Norman JT, Borras T, Grainger RM: Developmental regulation of hypomethylation of delta-crystallin genes in chicken embryo lens cells. Mol Cell Biol 9:3132, 1989
    • (1989) Mol Cell Biol , vol.9 , pp. 3132
    • Sullivan, C.H.1    Norman, J.T.2    Borras, T.3    Grainger, R.M.4
  • 69
    • 0023119242 scopus 로고
    • Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development
    • Monk M, Boubelik M, Lehnert S: Temporal and regional changes in DNA methylation in the embryonic, extraembryonic and germ cell lineages during mouse embryo development. Development 99:371, 1987
    • (1987) Development , vol.99 , pp. 371
    • Monk, M.1    Boubelik, M.2    Lehnert, S.3
  • 72
    • 0029946249 scopus 로고    scopus 로고
    • The DNA methylation machinery as a target for anticancer therapy
    • Szyf M: The DNA methylation machinery as a target for anticancer therapy. Pharmacol Therapeutics 70:1, 1996
    • (1996) Pharmacol Therapeutics , vol.70 , pp. 1
    • Szyf, M.1
  • 73
    • 0025637814 scopus 로고
    • Dynamics of demethylation and activation of the alpha-actin gene in myoblasts
    • Paroush Z, Keshet I, Yisraeli J, Cedar H: Dynamics of demethylation and activation of the alpha-actin gene in myoblasts. Cell 63:1229, 1990
    • (1990) Cell , vol.63 , pp. 1229
    • Paroush, Z.1    Keshet, I.2    Yisraeli, J.3    Cedar, H.4
  • 74
    • 0029055763 scopus 로고
    • Ras induces a general DNA demethylation activity in mouse embryonal P19 cells
    • Szyf M, Theberge J, Bozovic V: Ras induces a general DNA demethylation activity in mouse embryonal P19 cells. J Biol Chem 270:12690, 1995
    • (1995) J Biol Chem , vol.270 , pp. 12690
    • Szyf, M.1    Theberge, J.2    Bozovic, V.3
  • 75
    • 0028328632 scopus 로고
    • B cell-specific demethylation: A novel role for the intronic kappa chain enhancer sequence
    • Lichtenstein M, Keini G, Cedar H, Bergman Y: B cell-specific demethylation: A novel role for the intronic kappa chain enhancer sequence. Cell 76:913, 1994
    • (1994) Cell , vol.76 , pp. 913
    • Lichtenstein, M.1    Keini, G.2    Cedar, H.3    Bergman, Y.4
  • 77
    • 0027310491 scopus 로고
    • Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine
    • Jost JP: Nuclear extracts of chicken embryos promote an active demethylation of DNA by excision repair of 5-methyldeoxycytidine. Proc Natl Acad Sci USA 90:4684, 1993
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4684
    • Jost, J.P.1
  • 78
    • 0028934977 scopus 로고
    • Mechanisms of DNA demethylation in chicken embryos. Purification and properties of a 5-methylcytosine-DNA glycosylase
    • Jost JP, Siegmann M, Sun L, Leung R: Mechanisms of DNA demethylation in chicken embryos. Purification and properties of a 5-methylcytosine-DNA glycosylase. J Biol Chem 270:9734, 1995
    • (1995) J Biol Chem , vol.270 , pp. 9734
    • Jost, J.P.1    Siegmann, M.2    Sun, L.3    Leung, R.4
  • 79
    • 0030572637 scopus 로고    scopus 로고
    • DNA demethylation in vitro: Involvement of RNA
    • Weiss A, Keshet I, Razin A, Cedar H: DNA demethylation in vitro: involvement of RNA. Cell 86:709, 1996
    • (1996) Cell , vol.86 , pp. 709
    • Weiss, A.1    Keshet, I.2    Razin, A.3    Cedar, H.4
  • 80
    • 0032534635 scopus 로고    scopus 로고
    • Analysis of putative RNase sensitivity and protease insensitivity of demethylation activity in extracts from rat myoblasts
    • Swisher JF, Rand E, Cedar H, Marie Pyle A: Analysis of putative RNase sensitivity and protease insensitivity of demethylation activity in extracts from rat myoblasts. Nucleic Acids Res 26:5573, 1998
    • (1998) Nucleic Acids Res , vol.26 , pp. 5573
    • Swisher, J.F.1    Rand, E.2    Cedar, H.3    Marie Pyle, A.4
  • 81
    • 0033580326 scopus 로고    scopus 로고
    • A mammalian protein with specific demethylase activity for mCpG DNA
    • Bhattacharya SK, Ramchandani S, Cervoni N, Szyf M: A mammalian protein with specific demethylase activity for mCpG DNA. Nature 397:579, 1999
    • (1999) Nature , vol.397 , pp. 579
    • Bhattacharya, S.K.1    Ramchandani, S.2    Cervoni, N.3    Szyf, M.4
  • 82
    • 0031196156 scopus 로고    scopus 로고
    • The role of DNA demethylation during development
    • Weiss A, Cedar H: The role of DNA demethylation during development. Genes Cells 2:481, 1997
    • (1997) Genes Cells , vol.2 , pp. 481
    • Weiss, A.1    Cedar, H.2
  • 83
    • 0022971594 scopus 로고
    • DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture
    • Kautiainen TL, Jones PA: DNA methyltransferase levels in tumorigenic and nontumorigenic cells in culture. J Biol Chem 261: 1594, 1986
    • (1986) J Biol Chem , vol.261 , pp. 1594
    • Kautiainen, T.L.1    Jones, P.A.2
  • 87
    • 0030459140 scopus 로고    scopus 로고
    • The role of DNA methylation in cancer genetic and epigenetics
    • Laird PW, Jaenisch R: The role of DNA methylation in cancer genetic and epigenetics. Annu Rev Genet 30:441, 1996
    • (1996) Annu Rev Genet , vol.30 , pp. 441
    • Laird, P.W.1    Jaenisch, R.2
  • 88
    • 0018185292 scopus 로고
    • Molecular basis of base substitution hotspots in Escherichia coli
    • Coulondre C, Miller JH, Farabaugh PJ, Gilbert W: Molecular basis of base substitution hotspots in Escherichia coli. Nature 274:775, 1978
    • (1978) Nature , vol.274 , pp. 775
    • Coulondre, C.1    Miller, J.H.2    Farabaugh, P.J.3    Gilbert, W.4
  • 89
    • 0031050736 scopus 로고    scopus 로고
    • Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR
    • Gonzalgo ML, Liang G, Spruck CHr, Zingg JM, Rideout WMr, Jones PA: Identification and characterization of differentially methylated regions of genomic DNA by methylation-sensitive arbitrarily primed PCR. Cancer Res 57:594, 1997
    • (1997) Cancer Res , vol.57 , pp. 594
    • Gonzalgo, M.L.1    Liang, G.2    Spruck, C.Hr.3    Zingg, J.M.4    Rideout, W.Mr.5    Jones, P.A.6
  • 91
    • 0028071555 scopus 로고
    • Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
    • Greenblatt MS, Bennett WP, Hollstein M, Harris CC: Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855, 1994
    • (1994) Cancer Res , vol.54 , pp. 4855
    • Greenblatt, M.S.1    Bennett, W.P.2    Hollstein, M.3    Harris, C.C.4
  • 92
    • 0028333951 scopus 로고
    • Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer
    • Magewu AN, Jones PA: Ubiquitous and tenacious methylation of the CpG site in codon 248 of the p53 gene may explain its frequent appearance as a mutational hot spot in human cancer. Mol Cell Biol 14:4225, 1994
    • (1994) Mol Cell Biol , vol.14 , pp. 4225
    • Magewu, A.N.1    Jones, P.A.2
  • 94
    • 0027256637 scopus 로고
    • Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency
    • Christman JK, Sheikhnejad G, Dizik M, Abileah S, Wainfan E: Reversibility of changes in nucleic acid methylation and gene expression induced in rat liver by severe dietary methyl deficiency. Carcinogenesis 14:551, 1993
    • (1993) Carcinogenesis , vol.14 , pp. 551
    • Christman, J.K.1    Sheikhnejad, G.2    Dizik, M.3    Abileah, S.4    Wainfan, E.5
  • 95
    • 0031149098 scopus 로고    scopus 로고
    • Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat
    • Pogribny IP, Miller BJ, James SJ: Alterations in hepatic p53 gene methylation patterns during tumor progression with folate/methyl deficiency in the rat. Cancer Lett 115:31, 1997
    • (1997) Cancer Lett , vol.115 , pp. 31
    • Pogribny, I.P.1    Miller, B.J.2    James, S.J.3
  • 96
    • 0027239823 scopus 로고
    • bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia
    • Hanada M, Delia D, Aiello A, Stadtmauer E, Reed JC: bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia. Blood 82:1820, 1993
    • (1993) Blood , vol.82 , pp. 1820
    • Hanada, M.1    Delia, D.2    Aiello, A.3    Stadtmauer, E.4    Reed, J.C.5
  • 97
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg AP, Vogelstein B: Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 301:89, 1983
    • (1983) Nature , vol.301 , pp. 89
    • Feinberg, A.P.1    Vogelstein, B.2
  • 100
    • 0027537296 scopus 로고
    • CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene
    • Ohtani-Fujita N, Fujita T, Aoike A, Osifchin NE, Robbins PD, Sakai T: CpG methylation inactivates the promoter activity of the human retinoblastoma tumor-suppressor gene. Oncogene 8:1063, 1993
    • (1993) Oncogene , vol.8 , pp. 1063
    • Ohtani-Fujita, N.1    Fujita, T.2    Aoike, A.3    Osifchin, N.E.4    Robbins, P.D.5    Sakai, T.6
  • 103
    • 0344301900 scopus 로고    scopus 로고
    • Role of the p16 tumor suppressor gene in cancer
    • Liggett WH Jr, Sidransky D: Role of the p16 tumor suppressor gene in cancer. J Clin Oncol 16:1197, 1998
    • (1998) J Clin Oncol , vol.16 , pp. 1197
    • Liggett W.H., Jr.1    Sidransky, D.2
  • 104
    • 0029011539 scopus 로고
    • 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
    • Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, Baylin SB, Sidransky D: 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1:686, 1995
    • (1995) Nat Med , vol.1 , pp. 686
    • Merlo, A.1    Herman, J.G.2    Mao, L.3    Lee, D.J.4    Gabrielson, E.5    Burger, P.C.6    Baylin, S.B.7    Sidransky, D.8
  • 105
    • 0028845142 scopus 로고
    • Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
    • Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, Sidransky D, Baylin SB: Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 55:4525, 1995
    • (1995) Cancer Res , vol.55 , pp. 4525
    • Herman, J.G.1    Merlo, A.2    Mao, L.3    Lapidus, R.G.4    Issa, J.P.5    Davidson, N.E.6    Sidransky, D.7    Baylin, S.B.8
  • 107
    • 0028168242 scopus 로고
    • p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
    • Hannon GJ, Beach D: p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature 371:257, 1994
    • (1994) Nature , vol.371 , pp. 257
    • Hannon, G.J.1    Beach, D.2
  • 110
    • 0030983076 scopus 로고    scopus 로고
    • DNA methylation and genetic instability in colorectal cancer cells
    • Lengauer C, Kinzler KW, Vogelstein B: DNA methylation and genetic instability in colorectal cancer cells. Proc Natl Acad Sci USA 94:2545, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2545
    • Lengauer, C.1    Kinzler, K.W.2    Vogelstein, B.3
  • 111
    • 0030909592 scopus 로고    scopus 로고
    • Altered DNA methylation and genome instability: A new pathway to cancer?
    • Jones PA, Gonzalgo ML: Altered DNA methylation and genome instability: A new pathway to cancer? Proc Natl Acad Sci USA 94:2103, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 2103
    • Jones, P.A.1    Gonzalgo, M.L.2
  • 113
    • 0023848637 scopus 로고
    • Reduced genomic 5-methylcytosine content in human colonic neoplasia
    • Feinberg AP, Gehrke CW, Kuo KC, Ehrlich M: Reduced genomic 5-methylcytosine content in human colonic neoplasia. Cancer Res 48:1159, 1988
    • (1988) Cancer Res , vol.48 , pp. 1159
    • Feinberg, A.P.1    Gehrke, C.W.2    Kuo, K.C.3    Ehrlich, M.4
  • 114
    • 0009673698 scopus 로고    scopus 로고
    • Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid
    • Oneill RJW, Oneill MJ, Graves JAM: Undermethylation associated with retroelement activation and chromosome remodelling in an interspecific mammalian hybrid. Nature 393:68, 1998
    • (1998) Nature , vol.393 , pp. 68
    • Oneill, R.J.W.1    Oneill, M.J.2    Graves, J.A.M.3
  • 115
    • 0029046134 scopus 로고
    • Regulation of DNA methylation by the Ras signaling pathway
    • MacLeod AR, Rouleau J, Szyf M: Regulation of DNA methylation by the Ras signaling pathway. J Biol Chem 270:11327, 1995
    • (1995) J Biol Chem , vol.270 , pp. 11327
    • MacLeod, A.R.1    Rouleau, J.2    Szyf, M.3
  • 116
    • 0029847223 scopus 로고    scopus 로고
    • Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene
    • Tucker KL, Talbot D, Lee MA, Leonhardt H, Jaenisch R: Complementation of methylation deficiency in embryonic stem cells by a DNA methyltransferase minigene. Proc Natl Acad Sci USA 93:12920, 1996
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12920
    • Tucker, K.L.1    Talbot, D.2    Lee, M.A.3    Leonhardt, H.4    Jaenisch, R.5
  • 117
    • 0033555953 scopus 로고    scopus 로고
    • Role of DNA 5-methylcytosine transferase in cell transformation by fos
    • Bakin AV, Curran T: Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science 283:387, 1999
    • (1999) Science , vol.283 , pp. 387
    • Bakin, A.V.1    Curran, T.2
  • 118
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang LS, Ian HI, Koh TW, Ng HH, Xu G, Li BF: Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277:1996, 1997
    • (1997) Science , vol.277 , pp. 1996
    • Chuang, L.S.1    Ian, H.I.2    Koh, T.W.3    Ng, H.H.4    Xu, G.5    Li, B.F.6
  • 119
    • 0020624202 scopus 로고
    • DNA methylation and the regulation of globin gene expression
    • Busslinger M, Hurst J, Flavell RA: DNA methylation and the regulation of globin gene expression. Cell 34:197, 1983
    • (1983) Cell , vol.34 , pp. 197
    • Busslinger, M.1    Hurst, J.2    Flavell, R.A.3
  • 120
    • 0000206049 scopus 로고
    • 5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons
    • DeSimone J, Heller P, Hall L, Zwiers D: 5-Azacytidine stimulates fetal hemoglobin synthesis in anemic baboons. Proc Natl Acad Sci USA 79:4428, 1982
    • (1982) Proc Natl Acad Sci USA , vol.79 , pp. 4428
    • DeSimone, J.1    Heller, P.2    Hall, L.3    Zwiers, D.4
  • 122
    • 0004959517 scopus 로고
    • Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex
    • Charache S, Dover G, Smith K, Talbot CC Jr, Moyer M, Boyer S: Treatment of sickle cell anemia with 5-azacytidine results in increased fetal hemoglobin production and is associated with nonrandom hypomethylation of DNA around the gamma-delta-beta-globin gene complex. Proc Natl Acad Sci USA 80:4842, 1983
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 4842
    • Charache, S.1    Dover, G.2    Smith, K.3    Talbot C.C., Jr.4    Moyer, M.5    Boyer, S.6
  • 124
    • 0021362464 scopus 로고
    • Arabinosylcytosine induces fetal hemoglobin in baboons by perturbing erythroid cell differentiation kinetics
    • Papayannopoulou T, Torrealba de Ron A, Veith R, Knitter G, Stamatoyannopoulos G: Arabinosylcytosine induces fetal hemoglobin in baboons by perturbing erythroid cell differentiation kinetics. Science 224:617, 1984
    • (1984) Science , vol.224 , pp. 617
    • Papayannopoulou, T.1    Torrealba De Ron, A.2    Veith, R.3    Knitter, G.4    Stamatoyannopoulos, G.5
  • 128
    • 0027193132 scopus 로고
    • Preliminary results with 5-aza-2′-deoxycytidine (DAC)-containing chemotherapy in patients with relapsed or refractory acute leukemia
    • The EORTC Leukemia Cooperative Group
    • Willemze R, Archimbaud E, Muus P: Preliminary results with 5-aza-2′-deoxycytidine (DAC)-containing chemotherapy in patients with relapsed or refractory acute leukemia. The EORTC Leukemia Cooperative Group. Leukemia 7:49, 1993 (suppl 1)
    • (1993) Leukemia , vol.7 , Issue.SUPPL. 1 , pp. 49
    • Willemze, R.1    Archimbaud, E.2    Muus, P.3
  • 129
    • 0031025621 scopus 로고    scopus 로고
    • Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide
    • Ramchandani S, MacLeod AR, Pinard M, von Hofe E, Szyf M: Inhibition of tumorigenesis by a cytosine-DNA, methyltransferase, antisense oligodeoxynucleotide. Proc Natl Acad Sci USA 94:684, 1997
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 684
    • Ramchandani, S.1    MacLeod, A.R.2    Pinard, M.3    Von Hofe, E.4    Szyf, M.5
  • 130
    • 0029685023 scopus 로고    scopus 로고
    • Alu: Structure, origin, evolution, significance and function of one-tenth of human DNA
    • Schmid CW: Alu: Structure, origin, evolution, significance and function of one-tenth of human DNA. Prog Nucleic Acid Res Mol Biol 53:283, 1996
    • (1996) Prog Nucleic Acid Res Mol Biol , vol.53 , pp. 283
    • Schmid, C.W.1
  • 133
    • 0019786495 scopus 로고
    • DNA methylation and gene expression: Endogenous retroviral genome becomes infectious after molecular cloning
    • Harbers K, Schnieke A, Stuhlmann H, Jahner D, Jaenisch R: DNA methylation and gene expression: Endogenous retroviral genome becomes infectious after molecular cloning. Proc Natl Acad Sci USA 78:7609, 1981
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 7609
    • Harbers, K.1    Schnieke, A.2    Stuhlmann, H.3    Jahner, D.4    Jaenisch, R.5
  • 134
    • 0021861476 scopus 로고
    • Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity
    • Jahner D, Jaenisch R: Retrovirus-induced de novo methylation of flanking host sequences correlates with gene inactivity. Nature 315:594, 1985
    • (1985) Nature , vol.315 , pp. 594
    • Jahner, D.1    Jaenisch, R.2
  • 135
    • 0025739324 scopus 로고
    • Spreading of DNA methylation across integrated foreign (adenovirus type 12) genomes in mammalian cells
    • Orend G, Kuhlmann I, Doerfler W: Spreading of DNA methylation across integrated foreign (adenovirus type 12) genomes in mammalian cells. J Virol 65:4301, 1991
    • (1991) J Virol , vol.65 , pp. 4301
    • Orend, G.1    Kuhlmann, I.2    Doerfler, W.3
  • 136
    • 0021087175 scopus 로고
    • Expression of the chloramphenicol acetyltransferase gene in mammalian cells under the control of adenovirus type 12 promoters: Effect of promoter methylation on gene expression
    • Kruczek I, Doerfler W: Expression of the chloramphenicol acetyltransferase gene in mammalian cells under the control of adenovirus type 12 promoters: Effect of promoter methylation on gene expression. Proc Natl Acad Sci USA 80:7586, 1983
    • (1983) Proc Natl Acad Sci USA , vol.80 , pp. 7586
    • Kruczek, I.1    Doerfler, W.2
  • 137
    • 0026573988 scopus 로고
    • Methylation of HSV-1 DNA as a mechanism of viral inhibition: Studies of an analogue of methyldeoxycytidine: Trifluoromethyldeoxycytidine(F3mdCyd)
    • Barletta J, Greer SB: Methylation of HSV-1 DNA as a mechanism of viral inhibition: Studies of an analogue of methyldeoxycytidine: Trifluoromethyldeoxycytidine(F3mdCyd). Antiviral Res 18:1, 1992
    • (1992) Antiviral Res , vol.18 , pp. 1
    • Barletta, J.1    Greer, S.B.2
  • 138
    • 0030689030 scopus 로고    scopus 로고
    • Methylation of the Epstein-Barr virus genome in normal lymphocytes
    • Robertson KD, Ambinder RF: Methylation of the Epstein-Barr virus genome in normal lymphocytes. Blood 90:4480, 1997
    • (1997) Blood , vol.90 , pp. 4480
    • Robertson, K.D.1    Ambinder, R.F.2
  • 139
    • 0028230779 scopus 로고
    • Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo
    • Challita PM, Kohn DB: Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivo. Proc Natl Acad Sci USA 91:2567, 1994
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2567
    • Challita, P.M.1    Kohn, D.B.2
  • 140
    • 85069121393 scopus 로고    scopus 로고
    • Ameliorazation of retroviral vector silencing in locus control region β-globin transgenic mice and trasduced F9 embryonic cells
    • in press
    • Osborne C, Pasceri P, Singal R, Ginder GR: Ameliorazation of retroviral vector silencing in locus control region β-globin transgenic mice and trasduced F9 embryonic cells. J Virol (in press)
    • J Virol
    • Osborne, C.1    Pasceri, P.2    Singal, R.3    Ginder, G.R.4


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