Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 33, 2011, Pages 13379-13386

  Lin, Wenchu ^a   Cao, Jian ^b   Liu, Jiayun ^a   Beshiri, Michael L ^c   Fujiwara, Yuko ^a   Francis, Joshua ^a   Cherniack, Andrew D ^d   Geisen, Christoph ^a,e   Blair, Lauren P ^b   Zou, Mike R ^b   Shen, Xiaohua ^a   Kawamori, Dan ^a   Liu, Zongzhi ^b   Grisanzio, Chiara ^a,f   Watanabe, Hideo ^a   Minamishima, Yoji Andrew ^a   Zhang, Qing ^a   Kulkarni, Rohit N ^a   Signoretti, Sabina ^a,f   Rodig, Scott J ^f   Bronson, Roderick T ^a   Orkin, Stuart H ^a,e,g   Tuck, David P ^b   Benevolenskaya, Elizaveta V ^c   Meyerson, Matthew ^a,d,h   Kaelin Jr , William G ^a,e   Yan, Qin ^b   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g HARVARD STEM CELL INSTITUTE   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

Chromatin modifier; Histone methyltransferase; Islet cell tumor; Mouse model; Neuroendocrine tumor

Indexed keywords

GENE PRODUCT; HISTONE; HISTONE DEMETHYLASE; HISTONE H3; LYSINE; PROTEIN MSI1; RETINOBLASTOMA BINDING PROTEIN 2; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR PAX3; TUBULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CARCINOGENESIS; CHROMATIN; CONTROLLED STUDY; DEMETHYLATION; EMBRYO; ENZYME ACTIVITY; EPIGENETICS; GENE; GENETIC TRANSCRIPTION; MEN1 GENE; METHYLATION; MOUSE; MULTIPLE ENDOCRINE NEOPLASIA; NONHUMAN; PRIORITY JOURNAL; RB1 GENE;

ANIMALS; ENZYME INHIBITORS; EPIGENOMICS; HISTONE DEMETHYLASES; HISTONES; METHYLATION; MICE; MICE, KNOCKOUT; NEOPLASMS; PROTO-ONCOGENE PROTEINS; RETINOBLASTOMA PROTEIN; RETINOL-BINDING PROTEINS, CELLULAR; SURVIVAL RATE;

MUS;

EID: 80051998696     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1110104108     Document Type: Article

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