The methyl-CpG-binding protein MeCP2 links DNA methylation to histone methylation

Journal of Biological Chemistry

Volumn 278, Issue 6, 2003, Pages 4035-4040

  Fuks, François ^a,c   Hurd, Paul J ^a   Wolf, Daniel ^a   Nan, Xinsheng ^b   Bird, Adrian P ^b   Kouzarides, Tony ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c FREE UNIVERSITY OF BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENES; GENETIC ENGINEERING;

BINDING PROTEINS;

PROTEINS;

DINUCLEOTIDE; DNA; HISTONE DEACETYLASE; HISTONE H3; LYSINE; METHYL CPG BINDING PROTEIN 2; PROTEIN METHYLTRANSFERASE; DNA BINDING PROTEIN; HISTONE; MECP2 PROTEIN, HUMAN; MECP2 PROTEIN, MOUSE; NONHISTONE PROTEIN; RECOMBINANT PROTEIN; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CHROMATIN STRUCTURE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; DNA MODIFICATION; ENZYME ACTIVITY; GENE CONTROL; GENE EXPRESSION REGULATION; GENE LOCATION; GENE SILENCING; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOSOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; REPRESSOR GENE; TRANSCRIPTION REGULATION; ANIMAL; CELL LINE; METABOLISM; METHYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERODIAGNOSIS;

ANIMALIA; MAMMALIA;

ANIMALS; CELL LINE; CHROMOSOMAL PROTEINS, NON-HISTONE; DNA METHYLATION; DNA-BINDING PROTEINS; HISTONE DEACETYLASES; HISTONES; HUMANS; METHYL-CPG-BINDING PROTEIN 2; METHYLATION; MICE; PRECIPITIN TESTS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 0037423186     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M210256200     Document Type: Article

References (24)

1. Bird, A. (2002) Genes Dev. 16, 6-21
2. Lewis, J. D., Meehan, R. R., Henzel, W. J., Maurer-Fogy, I., Jeppesen, P., Klein, F., and Bird, A. (1992) Cell 69, 905-914
3. Nan, X., Campoy, F. J., and Bird, A. (1997) Cell 88, 471-481
4. Nan, X., Ng, H. H., Johnson, C. A., Laherty, C. D., Turner, B. M., Eisenman, R. N., and Bird, A. (1998) Nature 393, 386-389
5. Jones, P. L., Veenstra, G. J., Wade, P. A., Vermaak, D., Kass, S. U., Landsberger, N., Strouboulis, J., and Wolffe, A. P. (1998) Nat. Genet. 19, 187-191
6. Kouzarides, T. (2002) Curr. Opin. Genet. Dev. (2002) 12, 198-209
7. Nielsen, S. J., Schneider, R., Bauer, U. M., Bannister, A. J., Morrison, A., O'Carroll, D., Firestein, R., Cleary, M., Jenuwein, T., Herrera, R. E., and Kouzarides, T. (2001) Nature 412, 561-565
8. Nan, X., Meehan, R. R., and Bird, A. (1993) Nucleic Acids Res. 21, 4886-4892
9. Guy, J., Hendrich, B., Holmes, M., Martin, J. E., and Bird, A. (2001) Nat. Genet. 27, 322-326
10. Bannister, A. J., and Kouzarides, T. (1996) Nature 384, 641-643
11. Fuks, F., Burgers, W. A., Brehm, A., Hughes-Davies, L., and Kouzarides, T. (2000) Nat. Genet. 24, 88-91
12. Dedon, P. C., Soults, J. A., Allis, C. D., and Gorovsky, M. A. (1991) Anal. Biochem. 197, 83-90
13. Orlando, V., Strutt, H., and Paro, R. (1997) Methods 11, 205-214
14. Lachner, M., O'Carroll, D., Rea, S., Mechtler, K., and Jenuwein, T. (2001) Nature 410, 116-120
15. O'Carroll, D., Scherthan, H., Peters, A. H., Opravil, S., Haynes, A. R., Laible, G., Rea, S., Schmid, M., Lebersorger, A., Jerratsch, M., Sattler, L., Mattei, M. G., Denny, P., Brown, S. D., Schweizer, D., and Jenuwein, T. (2000) Mol. Cell. Biol. 20, 9423-9433
16. Tachibana, M., Sugimoto, K., Fukushima, T., and Shinkai, Y. (2001) J. Biol. Chem. 276, 25309-25317
17. Yang, L., Xia, L., Wu, D. Y., Wang, H., Chansky, H. A., Schubach, W. H., Hickstein, D. D., and Zhang, Y. (2002) Oncogene 21, 148-152
18. Ogawa, H., Ishiguro, K., Gaubatz, S., Livingston, D. M., and Nakatani, Y. (2002) Science 296, 1132-1136
19. Tremblay, K. D., Duran, K. L., and Bartolomei, M. S. (1997) Mol. Cell. Biol. 17, 4322-4329
20. Drewell, R. A., Goddard, C. J., Thomas, J. O., and Surani, M. A. (2002) Nucleic Acids Res. 30, 1139-1144
21. Rea, S., Eisenhaber, F., O'Carroll, D., Strahl, B. D., Sun, Z. W., Schmid, M., Opravil, S., Mechtler, K., Ponting, C. P., Allis, C. D., and Jenuwein, T. (2000) Nature 406, 593-599
22. Bannister, A. J., Zegerman, P., Partridge, J. F., Miska, E. A., Thomas, J. O., Allshire, R. C., and Kouzarides, T. (2001) Nature 410, 120-124
23. Tamaru, H., and Selker, E. U. (2001) Nature 414, 277-283
24. Jackson, J. P., Lindroth, A. M., Cao, X., and Jacobsen, S. E. (2002) Nature 416, 556-560