Comprehensive review on the HSC70 functions, interactions with related molecules and involvement in clinical diseases and therapeutic potential

Pharmacology and Therapeutics

Volumn 136, Issue 3, 2012, Pages 354-374

  Liu, Tuoen ^a   Daniels, Christopher K ^b   Cao, Shousong ^c  

^a WASHINGTON UNIVERSITY   (United States)

^b IDAHO STATE UNIVERSITY   (United States)

^c ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

HSC70; HSP70; HSPa8; Molecular chaperone; Protein folding; Ubiquitination

Indexed keywords

DEATH RECEPTOR 3; GALACTOSAMINE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 70; KRUPPEL LIKE FACTOR 4; MESSENGER RNA; NATURAL PRODUCT; OXYMARINE; PROTEIN; PROTEIN DNAJ; RECEPTOR ASSOCIATING PROTEIN 46; THROMBOSPONDIN; TUMOR NECROSIS FACTOR RECEPTOR 1; UNCLASSIFIED DRUG;

BINDING SITE; CARCINOGENESIS; CARDIOVASCULAR DISEASE; CELL FUNCTION; CELL INTERACTION; CELL SURVIVAL; CELLULAR DISTRIBUTION; DRUG TARGETING; GENE CONTROL; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEPATITIS B; HUMAN; LIVER DISEASE; NEOPLASM; NEUROLOGIC DISEASE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; SOMATIC CELL GENETICS;

CARDIOVASCULAR DISEASES; GENE EXPRESSION REGULATION; HSC70 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIVER DISEASES; NEOPLASMS;

EID: 84867840534     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2012.08.014     Document Type: Review

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