Upregulation of dihydropyrimidinase-related protein 2, spectrin α II chain, heat shock cognate protein 70 pseudogene 1 and tropomodulin 2 after focal cerebral ischemia in rats-A proteomics approach

Neurochemistry International

Volumn 50, Issue 7-8, 2007, Pages 1078-1086

  Chen, A ^a   Liao, W P ^a   Lu, Q ^a   Wong, W S F ^a   Wong, P T H ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Cerebral ischemia; Protein expression; Proteome; Stroke

Indexed keywords

COLLAPSIN RESPONSE MEDIATOR PROTEIN; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; FODRIN; HEAT SHOCK COGNATE PROTEIN 70; MESSENGER RNA; TROPOMODULIN; TROPOMODULIN 2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL GROWTH; CELL MATURATION; CONTROLLED STUDY; DISEASE MODEL; GENE EXPRESSION; MALE; MASS SPECTROMETRY; NERVE CELL PLASTICITY; NERVE FIBER; NEURITE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PHOSPHORYLATION; PROTEOMICS; PSEUDOGENE; RAT; TWO DIMENSIONAL GEL ELECTROPHORESIS; UPREGULATION;

ANIMALS; BRAIN; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HSP70 HEAT-SHOCK PROTEINS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NERVE TISSUE PROTEINS; PROTEOMICS; PSEUDOGENES; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTRIN;

ANURA; RATTUS;

EID: 34250750650     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2006.11.008     Document Type: Article

References (55)

1. Ahn S.G., Kim S.A., Yoon J.H., and Vacratsis P. Heat-shock cognate 70 is required for the activation of heat-shock factor 1 in mammalian cells. Biochem. J. 392 (2005) 145-152
2. Aikman J., O'steen B., Silver X., Torres R., Boslaugh S., Blackband S., Padgett K., Wang K.K., Hayes R., and Pineda J. Alpha-II-spectrin after controlled cortical impact in the immature rat brain. Dev. Neurosci. 28 (2006) 457-465
3. Amano M., Fukata Y., and Kaibuchi K. Regulation and functions of Rho-associated kinase. Exp. Cell Res. 261 (2000) 44-51
4. Arimura N., Inagaki N., Chihara K., Menager C., Nakamura N., Amano M., Iwamatsu A., Goshima Y., and Kaibuchi K. Phosphorylation of collapsin response mediator protein-2 by Rho-kinase: evidence for two separate signaling pathways for growth cone collapse. J. Biol. Chem. 275 (2000) 23973-23980
5. Arimura N., Menager C., Kawano Y., Yoshimura T., Kawabata S., Hattori A., Fukata Y., Amano M., Goshima Y., Inagaki M., Morone N., Usukura J., and Kaibuchi K. Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol. Cell Biol. 25 (2005) 9973-9984
6. Bartus R.T., Elliott P.J., Hayward N.J., Dean R.J., Harbeson S., Straub J.A., Li Z., and Powers J.C. Calpain as a novel target for treating acute neurodegenerative disorders. Neurol. Res. 17 (1995) 249-258
7. Bémeur C., Ste-Marie L., Desjardins P., Hazell A.S., Vachon L., Butterworth R., and Montgomery J. Decreased β-actin mRNA expression in hyperglycemic focal cerebral ischemia in the rat. Neurosci. Lett. 357 (2004) 211-214
8. Boyd-Kimball D., Castegna A., Sultana R., Poon H.F., Petroze R., Lynn B.C., Klein J.B., and Butterfield D.A. Proteomic identification of proteins oxidized by Aβ (1-42) in synaptosomes: implications for Alzheimer's disease. Brain Res. 1044 (2005) 206-215
9. Castegna A., Aksenov M., Thongboonkerd V., Klein J.B., Pierce W.M., Booze R., Markesbery W.R., and Butterfield D.A. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part II. Dihydropyrimidinase-related protein 2, alpha-enolase and heat shock cognate 71. J. Neurochem. 82 (2002) 1524-1532
10. Chimon G.N., and Wong P.T.H. Ischemic tolerance and lipid peroxidation in the brain. Neuroreport 9 (1998) 2269-2272
11. Cole A.R., Causeret F., Yadirgi G., Hastie C.J., McLauchlan H., McManus E.J., Hernandez F., Eickholt B.J., Nikolic M., and Sutherland C. Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo. J. Biol. Chem. 281 (2006) 16591-16598
12. Cole A.R., Knebel A., Morrice N.A., Robertson L.A., et al. GSK-3 phosphorylation of the Alzheimer epitope within collapsin response mediator proteins regulates axon elongation in primary neurons. J. Biol. Chem. 279 (2004) 50176-50180
13. Cox P.R., Fowler V., Xu B., Sweatt J.D., Paylor R., and Zoghbi H.Y. Mice lacking tropomodulin-2 show enhanced long-term potentiation, hyperactivity, and deficits in learning and memory. Mol. Cell. Neurosci. 23 (2003) 1-12
14. Currie R.W., Ellison J.A., White R.F., Feuerstein G.Z., Wang X., and Barone F.C. Benign focal ischemic preconditioning induces neuronal Hsp70 and prolonged astrogliosis with expression of Hsp27. Brain Res. 863 (2000) 169-181
15. Dutta S., Chiu Y.C., Probert A.W., and Wang K.K. Selective release of calpain produced α II-spectrin (α-Fodrin) breakdown products by acute neuronal cell death. Biol. Chem. 383 (2002) 785-791
16. Engidawork E., Gulesserian T., Fountoulakis M., and Lubec G. Aberrant protein expression in cerebral cortex of fetus with Down syndrome. Neuroscience 122 (2003) 145-154
17. Farkas O., Polgar B., Szekeres-Bartho J., Doczi T., Povlishock J.T., and Buki A. Spectrin breakdown products in the cerebrospinal fluid in severe head injury-preliminary observations. Acta Neurochir. 147 (2005) 855-861
18. Franklin T.B., Krueger-Naug A.M., Clarke D.B., Arrigo A.P., and Currie R.W. The role of heat shock proteins Hsp70 and Hsp27 in cellular protection of the central nervous system. Int. J. Hyperther. 21 (2005) 379-392
19. Franzen B., Yang Y., Sunnemark D., Wickman M., Ottervald J., Oppermann M., and Sandberg K. Dihydropyrimidinase related protein-2 as a biomarker for temperature and time dependent post mortem changes in the mouse brain proteome. Proteomics 3 (2003) 1920-1929
20. Fukata Y., Itoh T.J., Kimura T., Menager C., Nishimura T., Shiromizu T., Watanabe H., Inagaki N., Iwamatsu A., Hotani H., and Kaibuchi K. CRMP-2 binds to tubulin heterodimers to promote microtubule assembly. Nat. Cell Biol. 4 (2002) 583-591
21. Gu Y., Hamajima N., and Ihara Y. Neurofibrillary tangle-associated collapsin response mediator protein-2 (CRMP-2) is highly phosphorylated on Thr-509, Ser-518, and Ser-522. Biochemistry 39 (2000) 4267-4275
22. Guzhova I.V., Arnholdt A.C., Darieva Z.A., Kinev A.V., Lasunskaia E.B., Nilsson K., Bozhkov V.M., Voronin A.P., and Margulis B.A. Effects of exogenous stress protein 70 on the functional properties of human promonocytes through binding to cell surface and internalization. Cell Stress Chaperones 3 (1998) 67-77
23. Hirotsune S., Yoshida N., Chen A., Garrett L., Sugiyama F., Takahashi S., Yagami K., Wynshaw-Boris A., and Yoshiki A. An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene. Nature 423 (2003) 91-96
24. Houenou L.J., Li L., Lei M., Kent C.R., and Tytell M. Exogenous heat shock cognate protein Hsc70 prevents axotomy-induced death of spinal sensory neurons. Cell Stress Chaperones 1 (1996) 161-166
25. Johnston-Wilson N.L., Sims C.D., Hofmann J.P., Anderson L., Shore A.D., Torrey E.F., and Yolken R.H. Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley Neuropathology Consortium. Mol. Psychiatr. 5 (2000) 142-149
26. Jope R.S., and Johnson G.V. The glamour and gloom of glycogen synthase kinase-3. Trends Biochem. Sci. 29 (2004) 95-102
27. Kaibuchi K., Kuroda S., and Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Ann. Rev. Biochem. 68 (1999) 459-486
28. Kermer P., Digicaylioglu M.H., Kaul M., Zapata J.M., Krajewska M., Stenner-Liewen F., Takayama S., Krajewski S., Lipton S.A., and Reed J.C. BAG1 over-expression in brain protects against stroke. Brain Pathol. 13 (2003) 495-506
29. Kobeissy F.H., Ottens A.K., Zhang Z., Liu M.C., Denslow N.D., Dave J.R., Tortella F.C., Hayes R.L., and Wang K.K. Novel differential neuroproteomics analysis of traumatic brain injury in rats. Mol. Cell. Proteomics 5 (2006) 1887-1898
30. Kong K.Y., and Kedes L. Leucine 135 of tropomodulin-1 regulates its association with tropomyosin, its cellular localization, and the integrity of sarcomeres. J. Biol. Chem. 281 (2006) 9589-9599
31. Kostyukova A.S., Rapp B.A., Choy A., Greenfield N.J., and Hitchcock-DeGregori S.E. Structural requirements of tropomodulin for tropomyosin binding and actin filament capping. Biochemistry 44 (2005) 4905-4910
32. Li W., Herman R.K., and Sham J.E. Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33. Genetics 132 (1992) 675-689
33. Lubec G., Nonaka M., Krapfenbauer K., Gratzer M., Cairns N., and Fountoulakis M. Expression of the dihydropyrimidinase related protein-2 (DRP-2) in Down syndrome and Alzheimer's disease brain is downregulated at the mRNA and dysregulated at the protein level. J. Neural Transm. Suppl. 57 (1999) 161-177
34. Maurer M.H., Berger C., Wolf M., Futterer C.D., Feldmann Jr. R.E., Schwab S., and Kuschinsky W. The proteome of human brain microdialysate. Proteome Sci. 1 (2003) 7
35. Minger S.L., Geddes J.W., Holtz M.L., Craddock S.D., Whiteheart S.W., Siman R.G., and Pettigrew L.C. Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia. Brain Res. 810 (1998) 181-199
36. Morano K.A., and Thiele D.J. Heat shock factor function and regulation in response to cellular stress, growth, and differentiation signals. Gene Expr. 7 (1999) 271-282
37. Planas A.M., Soriano M.A., Estrada A., Sanz O., Martin F., and Ferrer I. The heat shock protein stress response after brain lesions: induction of 72 kDa heat shock protein (cell types involved, axonal transport, transcriptional regulation) and protein synthesis inhibition. Prog. Neurobiol. 51 (1997) 607-636
38. Poon H.F., Vaishnav R.A., Getchell T.V., Getchell M.L., and Butterfield D.A. Quantitative proteomics analysis of differential protein expression and oxidative modification of specific proteins in the brains of old mice. Neurobiol. Aging 27 (2006) 1010-1019
39. Quinn C.C., Gray G.E., and Hockfield S. A family of proteins implicated in axon guidance and outgrowth. J. Neurobiol. 41 (1999) 158-164
40. Represa A., Tremblay E., and Ben-Ari Y. Sprouting of mossy fibers in the hippocampus of epileptic human and rat. Adv. Exp. Med. Biol. 268 (1990) 419-424
41. Sasara T., Cizkova D., Mestril R., Galik J., Sugahara K., and Marsala M. Spinal heat shock protein (70) expression: effect of spinal ischemia, hyperthermia (42_C)/hypothermia (27_C), NMDA receptor activation and potassium evoked depolarization on the induction. Neurochem. Int. 44 (2004) 53-64
42. Schonberger S.J., Edgar P.F., Kydd R., Faull R.L., and Cooper G.J. Proteomic analysis of the brain in Alzheimer's disease: molecular phenotype of a complex disease process. Proteomics 1 (2001) 1519-1528
43. Shuaib A., Yang Y., Nakada M.T., Li Q., and Yang T. Glycoprotein IIb/IIIa antagonist, murine 7E3 F(ab') 2, and tissue plasminogen activator in focal ischemia: evaluation of efficacy and risk of hemorrhage with combination therapy. J. Cereb. Blood Flow Metab. 22 (2002) 215-222
44. Sultana R., Boyd-Kimball D., Poon H.F., Cai J., Pierce W.M., Klein J.B., Merchant M., Markesbery W.R., and Butterfield D.A. Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD. Neurobiol. Aging 27 (2006) 1564-1576
45. Sussman M.A., Sakhi S., Tocco G., Najm I., Baudry M., Kedes L., and Schreiber S.S. Neural tropomodulin: developmental expression and effect of seizure activity. Brain Res. Dev. Brain Res. 80 (1994) 45-53
46. Suzuki Y., Nakagomi S., Namikawa K., Kiryu-Seo S., Inagaki N., Kaibuchi K., Aizawa H., Kikuchi K., and Kiyama H. Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat. J. Neurochem. 86 (2003) 1042-1050
47. Tahimic C.G., Tomimatsu N., Nishigaki R., Fukuhara A., Toda T., Kaibuchi K., Shiota G., Oshimura M., and Kurimasa A. Evidence for a role of collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells. Biochem. Biophys. Res. Commun. 340 (2006) 1244-1250
48. Takayama S., Bimston D.N., Matsuzawa S., Freeman B.C., Aime-Sempe C., Xie Z., Morimoto R.I., and Reed J.C. BAG-1 modulates the chaperone activity of Hsp70/Hsc70. EMBO J. 16 (1997) 4887-4896
49. Veyrac A., Giannetti N., Charrier E., Reymond-Marron I., Aguera M., Rogemond V., Honnorat J., and Jourdan F. Expression of collapsin response mediator proteins 1, 2 and 5 is differentially regulated in newly generated and mature neurons of the adult olfactory system. Eur. J. Neurosci. 21 (2005) 2635-2648
50. Weitzdoerfer R., Fountoulakis M., and Lubec G. Aberrant expression of dihydropyrimidinase related protein-2, -3, and -4 in fetal Down syndrome brain. J. Neural Transm. Suppl. 61 (2001) 95-107
51. Winkelmann J.C., and Forget B.G. Erythroid and nonerythroid spectrins. Blood 81 (1993) 3173-3185
52. Yoshida H., Watanabe A., and Ihara Y. Collapsin response mediator protein-2 is associated with neurofibrillary tangles in Alzheimer's disease. J. Biol. Chem. 273 (1998) 9761-9768
53. Yoshimura T., Kawano Y., Arimura N., Kawabata S., Kikuchi A., and Kaibuchi K. GSK-3β regulates phosphorylation of CRMP-2 and neuronal polarity. Cell 120 (2005) 137-149
54. Zabel C., Chamrad D.C., Priller J., Woodman B., Meyer H.E., Bates G.P., and Klose J. Alterations in the mouse and human proteome caused by Huntington's disease. Mol. Cell. Proteomics 1 (2002) 366-375
55. Zhao J., Zhu H., Wong C.H., Leung K.Y., and Wong W.S.F. Increased lungkine and chitinase levels in allergic airway inflammation: a proteomics approach. Proteomics 5 (2005) 2799-2807