Lysosomal degradation of α-synuclein in vivo

Journal of Biological Chemistry

Volumn 285, Issue 18, 2010, Pages 13621-13629

  Mak, Sally K ^a   McCormack, Alison L ^b   Manning Bog, Amy B ^b   Cuervo, Ana Maria ^c   Di Monte, Donato A ^b  

^a PARKINSON S INSTITUTE   (United States)

^b SRI INTERNATIONAL   (United States)

^c ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; CHAPERONE-MEDIATED AUTOPHAGY; DOPAMINERGIC NEURONS; ESSENTIAL COMPONENT; HEAT-SHOCK; HERBICIDE PARAQUAT; IMMUNOFLUORESCENCE MICROSCOPY; IN-VITRO; IN-VIVO; LYSOSOMAL DEGRADATION; MEMBRANE PROTEINS; MIDBRAIN; NEURODEGENERATIVE; NEURODEGENERATIVE DISEASE; NORMAL CONDITION; OVER-EXPRESSION; PROTEIN DEGRADATION; SYNUCLEIN; TRANSGENICS;

ANIMALS; BIOLOGICAL MEMBRANES; DEGRADATION; HERBICIDES; NEURONS;

PROTEINS;

ALPHA SYNUCLEIN; CHAPERONE; HEAT SHOCK COGNATE PROTEIN 70; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; PARAQUAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CLEARANCE; DOPAMINERGIC NERVE CELL; IMMUNOFLUORESCENCE MICROSCOPY; IN VIVO STUDY; INTOXICATION; LYSOSOME; MALE; MESENCEPHALON; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; DISEASE MODELS, ANIMAL; HERBICIDES; HSC70 HEAT-SHOCK PROTEINS; HUMANS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOMES; MALE; MESENCEPHALON; MICE; MICE, TRANSGENIC; NEURONS; PARAQUAT; PARKINSON DISEASE;

ANIMALIA; MUS;

EID: 77951541740     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.074617     Document Type: Article

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