Small molecular compounds that inhibit hepatitis C virus replication through destabilizing heat shock cognate 70 messenger RNA

Hepatology

Volumn 52, Issue 3, 2010, Pages 845-853

  Peng, Zong Gen ^a   Fan, Bo ^a   Du, Na Na ^a   Wang, Yu Ping ^a   Gao, Li Mei ^a   Li, Ying Hong ^a   Li, Yu Huan ^a   Liu, Fei ^a   You, Xue Fu ^a   Han, Yan Xing ^a   Zhao, Zhi Yun ^a   Cen, Shan ^a   Li, Jian Rui ^a   Song, Dan Qing ^a   Jiang, Jian Dong ^a  

^a INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

4 [2 (4 METHOXYBENZYL)PERHYDROPYRIDO[3,2,1-IJ][1,6] NAPHTHYRIDIN 1 YL]BUTANOIC ACID; ANTIVIRUS AGENT; HEAT SHOCK COGNATE PROTEIN 70; IMB DM 122; MESSENGER RNA; UNCLASSIFIED DRUG; 4-(2-(4-METHOXYBENZYL)PERHYDROPYRIDO(3,2,1-IJ)(1,6)NAPHTHYRIDIN-1-YL)BUTANOIC ACID; MOLECULAR LIBRARY; NAPHTHYRIDINE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG CYTOTOXICITY; DRUG MECHANISM; FEMALE; GENE EXPRESSION REGULATION; HALF LIFE TIME; HEPATITIS C; HEPATITIS C VIRUS; HOST; HUMAN; HUMAN CELL; KIDNEY FUNCTION; LIVER CELL; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; UNTRANSLATED REGION; VIRION; VIRUS REPLICATION; ANIMAL; CELL CULTURE; DRUG EFFECTS; GENETICS; HEPACIVIRUS; INBRED MOUSE STRAIN; LIVER; METABOLISM; MOLECULAR LIBRARY; PATHOLOGY; PHARMACOLOGY; PHYSIOLOGY; VIROLOGY;

ANIMALS; CELLS, CULTURED; DOWN-REGULATION; FEMALE; HEPACIVIRUS; HEPATOCYTES; HSC70 HEAT-SHOCK PROTEINS; HUMANS; LIVER; MALE; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; NAPHTHYRIDINES; RNA, MESSENGER; SMALL MOLECULE LIBRARIES; VIRUS REPLICATION;

EID: 77956641825     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.23766     Document Type: Article

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