Carboxyl terminus of heat-shock cognate 70-interacting protein degrades tau regardless its phosphorylation status without affecting the spatial memory of the rats

Journal of Neural Transmission

Volumn 115, Issue 3, 2008, Pages 483-491

  Zhang, Y J ^a   Xu, Y F ^a   Liu, X H ^a   Li, D ^a   Yin, J ^a   Liu, Y H ^a   Chen, X Q ^a   Wang, J Z ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Alzheimer's disease; Carboxyl terminus of heat shock cognate 70 interacting protein; Phosphorylation; Tau

Indexed keywords

2 [1 (3 DIMETHYLAMINOPROPYL) 3 INDOLYL] 3 (3 INDOLYL)MALEIMIDE; GLYCOGEN SYNTHASE KINASE 3; HEAT SHOCK COGNATE PROTEIN 70; MESSENGER RNA; TAU PROTEIN; WORTMANNIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; GENE OVEREXPRESSION; HIPPOCAMPUS; MALE; MEMORY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; SPATIAL MEMORY; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; HSC70 HEAT-SHOCK PROTEINS; MALE; MAZE LEARNING; MEMORY; PHOSPHORYLATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPATIAL BEHAVIOR; TAU PROTEINS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES;

EID: 49949152486     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0857-7     Document Type: Article

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