An analog of a dipeptide-like structure of FK506 increases glial cell line-derived neurotrophic factor expression through cAMP response element-binding Protein activated by heat shock protein 90/Akt signaling pathway

Journal of Neuroscience

Volumn 26, Issue 12, 2006, Pages 3335-3344

  Cen, Xiaobo ^a,b   Nitta, Atsumi ^a   Ohya, Shin ^a   Zhao, Yinglan ^a   Ozawa, Naoya ^a   Mouri, Akihiro ^a   Ibi, Daisuke ^a,f   Wang, Li ^b   Suzuki, Makiko ^c   Saito, Kuniaki ^c   Ito, Yasutomo ^a   Kawagoe, Tetsuya ^d   Noda, Yukihiro ^a,e   Ito, Yoshihisa ^a,f   Furukawa, Shoei ^g   Nabeshima, Toshitaka ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b SICHUAN UNIVERSITY   (China)

^c GIFU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Initium ^*  (Japan)

^e MEIJO UNIVERSITY   (Japan)

^f NIHON UNIVERSITY   (Japan)

^g GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

CREB; Dipeptide; FK506; GDNF; Hsc70; Hsp90

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BINDING PROTEIN; CYCLIC AMP; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DIPEPTIDE; FLUORESCEIN ISOTHIOCYANATE; GELDANAMYCIN; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 90; PROTEIN KINASE B; SILICON DIOXIDE; TSUKUBAENOLIDE;

ANIMAL TISSUE; ARTICLE; BINDING SITE; CRYSTAL; DRUG ACTIVITY; DRUG INHIBITION; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOLECULAR MODEL; MOUSE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT;

ANIMALS; BINDING SITES; CELL MEMBRANE; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DIPEPTIDES; ENZYME INHIBITORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HIPPOCAMPUS; HSC70 HEAT-SHOCK PROTEINS; HSP90 HEAT-SHOCK PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TACROLIMUS; UP-REGULATION;

EID: 33645231485     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5010-05.2006     Document Type: Article

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