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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 16, 2011, Pages 4732-4735

Synthesis, structure-activity relationship and biological evaluation of novel N-substituted matrinic acid derivatives as host heat-stress cognate 70 (Hsc70) down-regulators

(10) Du, Na Na a Li, Xin a Wang, Yu Ping a Liu, Fei a Liu, Yan Xin a Li, Chun Xin a Peng, Zong Gen a Gao, Li Mei a Jiang, Jian Dong a Song, Dan Qing a

a INSTITUTE OF MEDICINAL BIOTECHNOLOGY (China)

Author keywords

Anti HBV activity; Down regulators; Heat stress cognate 70 (Hsc70); Mechanism; N Substituted matrinic acid; Structure activity relationship

Indexed keywords

ALKALOID DERIVATIVE; ANTIVIRUS AGENT; CARBOXYL GROUP; HEAT SHOCK COGNATE PROTEIN 70; MATRINIC ACID DERIVATIVE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG SYNTHESIS; GENE EXPRESSION; HEPATITIS B VIRUS; NONHUMAN; PROTEIN EXPRESSION; STRUCTURE ACTIVITY RELATION;

ANTI-BACTERIAL AGENTS; BUTYRIC ACIDS; DOWN-REGULATION; HEPACIVIRUS; HEPATITIS B VIRUS; HSC70 HEAT-SHOCK PROTEINS; MOLECULAR CONFORMATION; QUINOLIZINES; RNA, MESSENGER; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS B VIRUS;

EID: 79960926258 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.06.071 Document Type: Article

Times cited : (54)

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