Transgenic expression of Hsc70 in pancreatic islets enhances autoimmune diabetes in response to β cell damage

Journal of Immunology

Volumn 183, Issue 9, 2009, Pages 5728-5737

  Alam, Masih Ul ^a   Harken, Julie A ^a   Knorn, Anna Maria ^a   Elford, Alisha R ^b   Wigmore, Kip ^b   Ohashi, Pamela S ^b   Millar, Douglas G ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; HEAT SHOCK COGNATE PROTEIN 70;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; APOPTOSIS; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNITY; CELL DAMAGE; CELL DEATH; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC SUSCEPTIBILITY; INFLAMMATION; LYMPH NODE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEADY STATE; STREPTOZOCIN DIABETES; T LYMPHOCYTE; TRANSGENIC MOUSE; TRANSGENICS;

ANIMALS; AUTOIMMUNE DISEASES; CATTLE; CD8-POSITIVE T-LYMPHOCYTES; CELL DEATH; CELL MOVEMENT; CYTOSOL; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; HSC70 HEAT-SHOCK PROTEINS; INCIDENCE; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, TRANSGENIC; RATS;

EID: 77954155091     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0901288     Document Type: Article

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