Repressive domain of unliganded human estrogen receptor α associates with Hsc70

Genes to Cells

Volumn 10, Issue 12, 2005, Pages 1095-1102

  Ogawa, Satoko ^a   Oishi, Hajime ^a   Mezaki, Yoshihiro ^a   Kouzu Fujita, Madoka ^a   Matsuyama, Reiko ^a   Nakagomi, Madoka ^a   Mori, Eri ^a   Murayama, Emi ^b   Nagasawa, Hiromichi ^b   Kitagawa, Hirochika ^a   Yanagisawa, Junn ^a   Yano, Tetsu ^a   Kato, Shigeaki ^a,c  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; ESTROGEN RECEPTOR ALPHA; HEAT SHOCK COGNATE PROTEIN 70; LIGAND; PROTEIN P300;

AMINO TERMINAL SEQUENCE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; GENE CONTROL; GENE MAPPING; GENE TARGETING; HORMONE BINDING; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

CELLS, CULTURED; ESTROGEN RECEPTOR ALPHA; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HELA CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LIGANDS; MOLECULAR CHAPERONES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; REPRESSOR PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 29244464699     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2005.00904.x     Document Type: Article

References (37)

1. Alberti, S., Demand, J., Esser, C., Emmerich, N., Schild, H. & Hohfeld, J. (2002) Ubiquitylation of BAG-1 suggests a novel regulatory mechanism during the sorting of chaperone substrates to the proteasome. J. Biol. Chem. 277, 45920-45927.
2. Ballinger, C.A., Connell, P., Wu, Y., et al. (1999) Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions. Mol. Cell. Biol. 19, 4535-4545.
3. Belandia, B. & Parker, M.G. (2003) Nuclear receptors: a rendezvous for chromatin remodeling factors. Cell 114, 277-280.
4. Chen, H., Lin, R.J., Schiltz, R.L., et al. (1997) Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300. Cell 90, 569-580.
5. Ciana, P., Raviscioni, M., Mussi, P., et al. (2003) In vivo imaging of transcriptionally active estrogen receptors. Nature Med. 9, 82-86.
6. Couse, J.F. & Korach, K.S. (1999) Estrogen receptor null mice: what have we learned and where will they lead us? Endocr. Rev. 20, 358-417.
7. Endoh, H., Maruyama, K., Masuhiro, Y., et al. (1999) Purification and identification of p68 RNA helicase acting as a transcriptional coactivator specific for the activation function 1 of human estrogen receptor alpha. Mol. Cell. Biol. 19, 5363-5372.
8. Fondell, J.D., Ge, H. & Roeder, R.G. (1996) Ligand induction of a transcriptionally active thyroid hormone receptor coactivator complex. Proc. Natl. Acad. Sci. USA 93, 8329-8333.
9. Freedman, L.P. (1999) Increasing the complexity of coactivation in nuclear receptor signaling. Cell 97, 5-8.
10. Glass, C.K. & Rosenfeld, M.G. (2000) The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev. 14, 121-141.
11. Ito, S., Takeyama, K., Yamamoto, A., et al. (2004) In vivo potentiation of human oestrogen receptor alpha by Cdk7-mediated phosphorylation. Genes Cells 9, 983-992.
12. Jepsen, K., Hermanson, O., Onami, T.M., et al. (2000) Combinatorial roles of the nuclear receptor corepressor in transcription and development. Cell 102, 753-763.
13. Kamei, Y., Xu, L., Heinzel, T., et al. (1996) A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85, 403-414.
14. Kitagawa, H., Fujiki, R., Yoshimura, K., et al. (2003) The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell 113, 905-917.
15. Kobayashi, Y., Kitamoto, T., Masuhiro, Y., et al. (2000) p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains. J. Biol. Chem. 275, 15645-15651.
16. Kumar, V., Green, S., Stack, G., Berry, M., Jin, J.R. & Chambon, P. (1987) Functional domains of the human estrogen receptor. Cell 51, 941-951.
17. Kurokawa, R., Soderstrom, M., Horlein, A., et al. (1995) Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature 377, 451-454.
18. Mangelsdorf D.J., Thummel, C., Beato, M., et al. (1995) The nuclear receptor superfamily: the second decade. Cell 83, 835-839.
19. McKenna, N.J. & O'Malley, B.W. (2002) Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108, 465-474.
20. Metivier, R., Penot, G., Hubner, M.R., et al. (2003) Estrogen receptor-alpha directs ordered, cyclical, and combinatorial recruitment of cofactors on a natural target promoter. Cell 115, 751-763.
21. Naar, A.M., Beaurang, P.A., Zhou, S., Abraham, S., Solomon, W. & Tjian, R. (1999) Composite co-activator ARC mediates chromatin-directed transcriptional activation. Nature 398, 828-832.
22. Nagy, L., Kao, H.Y., Chakravarti, D., et al. (1997) Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase. Cell 89, 373-380.
23. Onate, S.A., Tsai, S.Y., Tsai, M.J. & O'Malley, B.W. (1995) Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270, 1354 -1357.
24. Picard, D., Khursheed, B., Garabedian, M.J., Fortin, M.G., Lindquist, S. & Yamamoto, K.R. (1990) Reduced levels of hsp90 compromise steroid receptor action in vivo. Nature 348, 166-168.
25. Rachez, C., Lemon, B.D., Suldan, Z., et al. (1999) Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex. Nature 398, 824-828.
26. Shiau, A.K., Barstad, D., Radek, J.T., et al. (2002) Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nature Struct. Biol. 9, 359-364.
27. Spencer, T.E., Jenster, G., Burcin, M.M., et al. (1997) Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 389, 194-198.
28. Takeyama, K., Masuhiro, Y., Fuse, H., et al. (1999) Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog. Mol. Cell. Biol. 19, 1049-1055.
29. Tateishi, Y., Kawabe, Y., Chiba, T., et al. (2004) Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor. EMBO J. 23, 4813-4823.
30. Tora, L., White, J., Brou, C., et al. (1989) The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59, 477-487.
31. Watanabe, M., Yanagisawa, J., Kitagawa, H., et al. (2001) A sub-family of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. EMBO J. 20, 1341-1352.
32. Wu, Y.L., Yang, X., Ren, Z., et al. (2005) Structural basis for an unexpected mode of SERM-mediated ER antagonism. Mol. Cell 18, 413-424.
33. Yamamoto, Y., Wada, O., Suzawa, M., et al. (2001) The tamoxifen-responsive estrogen receptor alpha mutant D351Y shows reduced tamoxifen-dependent interaction with corepressor complexes. J. Biol. Chem. 276, 42684-42691.
34. Yanagisawa, J., Kitagawa, H., Yanagida, M., et al. (2002) Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol. Cell 9, 553-562.
35. Yanagisawa, J., Yanagi, Y., Masuhiro, Y., et al. (1999) Convergence of transforming growth factor-beta and vitamin D signaling pathways on SMAD transcriptional coactivators. Science 283, 1317-1321.
36. Ylikomi, T., Bocquel, M.T., Berry, M., Gronemeyer, H. & Chambon, P. (1992) Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J. 11, 3681-3694.
37. Yuan, C.X., Ito, M., Fondell, J.D., Fu, Z.Y. & Roeder, R.G. (1998) The TRAP220 component of a thyroid hormone receptor-associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion. Proc. Natl. Acad. Sci. USA 95, 7939-7944.