-
1
-
-
55749089875
-
Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes
-
Aasen, T., Raya, A., Barrero, M. J., Gar-reta, E., Consiglio, A., Gonzalez, F., Vassena, R., Bilic, J., Pekarik, V., Tis-cornia, G., Edel, M., Boue, S., and Belmonte, J. C. I. (2008). Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes. Nat. Biotechnol. 26, 1276-1284.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1276-1284
-
-
Aasen, T.1
Raya, A.2
Barrero, M.J.3
Gar-reta, E.4
Consiglio, A.5
Gonzalez, F.6
Vassena, R.7
Bilic, J.8
Pekarik, V.9
Tis-cornia, G.10
Edel, M.11
Boue, S.12
Belmonte, J.C.I.13
-
2
-
-
53049105819
-
ALS drug development: reflections from the past and a way forward
-
Aggarwal, S., and Cudkowicz, M. (2008). ALS drug development: reflections from the past and a way forward. Neurotherapeutics 5, 516-527.
-
(2008)
Neurotherapeutics
, vol.5
, pp. 516-527
-
-
Aggarwal, S.1
Cudkowicz, M.2
-
3
-
-
83255189758
-
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
-
Amps, K. A. P., Anyfantis, G., Armstrong, L., Avery, S., Baharvand, H., Baker, J., Baker, D., Munoz, M. S., Beil, S., Benvenisty, N., Ben-Yosef, D., Biancotti, J. C., Bosman, A., Brena, R. M., Brison, D., Caisander, G., Cama-rasa, M. V., Chen, J., Chiao, E., Choi, Y. M., Choo, A. B., Collins, D., Col-man, A., Crook, J. M., Daley, G. Q., Dalton, A., De Sousa, P. A., Denning, C., Downie, J., Dvorak, P., Montgomery, K. D., Feki, A., Ford, A., Fox, V., Fraga, A. M., Frumkin, T., Ge, L., Gokhale, P. J., Golan-Lev, T., Gourabi, H., Gropp, M., Lu, G., Hampl, A., Harron, K., Healy, L., Herath, W., Holm, F., Hovatta, O., Hyllner, J., Inamdar, M. S., Irwanto, A. K., Ishii, T., Jaconi, M., Jin, Y., Kimber, S., Kiselev, S., Knowles, B. B., Kopper, O., Kukharenko, V., Kuliev, A., Lagarkova, M. A., Laird, P. W., Lako, M., Laslett, A. L., Lavon, N., Lee, D. R., Lee, J. E., Li, C., Lim, L. S., Ludwig, T. E., Ma, Y., Maltby, E., Mateizel, I., Mayshar, Y., Mileikovsky, M., Minger, S. L., Miyazaki, T., Moon, S. Y., Moore, H., Mummery, C., Nagy, A., Nakat-suji, N., Narwani, K., Oh, S. K., Oh, S. K., Olson, C., Otonkoski, T., Pan, F., Park, I. H., Pells, S., Pera, M. F., Pereira, L. V., Qi, O., Raj, G. S., Reubinoff, B., Robins, A., Rob-son, P., Rossant, J., Salekdeh, G. H., Schulz, T. C., Sermon, K., Sheik Mohamed, J., Shen, H., Sherrer, E., Sidhu, K., Sivarajah, S., Skottman, H., Spits, C., Stacey, G. N., Strehl, R., Strelchenko, N., Suemori, H., Sun, B., Suuronen, R., Takahashi, K., Tuuri, T., Venu, P., Verlinsky,Y., Ward-Van Oostwaard, D., Weisen-berger, D. J., Wu, Y., Yamanaka, S., Young, L., and Zhou, Q. (2011). Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat. Biotechnol. 29, 1132-1144.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 1132-1144
-
-
Amps, K.A.P.1
Anyfantis, G.2
Armstrong, L.3
Avery, S.4
Baharvand, H.5
Baker, J.6
Baker, D.7
Munoz, M.S.8
Beil, S.9
Benvenisty, N.10
Ben-Yosef, D.11
Biancotti, J.C.12
Bosman, A.13
Brena, R.M.14
Brison, D.15
Caisander, G.16
Cama-rasa, M.V.17
Chen, J.18
Chiao, E.19
Choi, Y.M.20
Choo, A.B.21
Collins, D.22
Col-man, A.23
Crook, J.M.24
Daley, G.Q.25
Dalton, A.26
De Sousa, P.A.27
Denning, C.28
Downie, J.29
Dvorak, P.30
Montgomery, K.D.31
Feki, A.32
Ford, A.33
Fox, V.34
Fraga, A.M.35
Frumkin, T.36
Ge, L.37
Gokhale, P.J.38
Golan-Lev, T.39
Gourabi, H.40
Gropp, M.41
Lu, G.42
Hampl, A.43
Harron, K.44
Healy, L.45
Herath, W.46
Holm, F.47
Hovatta, O.48
Hyllner, J.49
Inamdar, M.S.50
Irwanto, A.K.51
Ishii, T.52
Jaconi, M.53
Jin, Y.54
Kimber, S.55
Kiselev, S.56
Knowles, B.B.57
Kopper, O.58
Kukharenko, V.59
Kuliev, A.60
Lagarkova, M.A.61
Laird, P.W.62
Lako, M.63
Laslett, A.L.64
Lavon, N.65
Lee, D.R.66
Lee, J.E.67
Li, C.68
Lim, L.S.69
Ludwig, T.E.70
Ma, Y.71
Maltby, E.72
Mateizel, I.73
Mayshar, Y.74
Mileikovsky, M.75
Minger, S.L.76
Miyazaki, T.77
Moon, S.Y.78
Moore, H.79
Mummery, C.80
Nagy, A.81
Nakat-suji, N.82
Narwani, K.83
Oh, S.K.84
Oh, S.K.85
Olson, C.86
Otonkoski, T.87
Pan, F.88
Park, I.H.89
Pells, S.90
Pera, M.F.91
Pereira, L.V.92
Qi, O.93
Raj, G.S.94
Reubinoff, B.95
Robins, A.96
Rob-son, P.97
Rossant, J.98
Salekdeh, G.H.99
Schulz, T.C.100
Sermon, K.101
Sheik Mohamed, J.102
Shen, H.103
Sherrer, E.104
Sidhu, K.105
Sivarajah, S.106
Skottman, H.107
Spits, C.108
Stacey, G.N.109
Strehl, R.110
Strelchenko, N.111
Suemori, H.112
Sun, B.113
Suuronen, R.114
Takahashi, K.115
Tuuri, T.116
Venu, P.117
Verlinsky, Y.118
Ward-Van Oostwaard, D.119
Weisen-berger, D.J.120
Wu, Y.121
Yamanaka, S.122
Young, L.123
Zhou, Q.124
more..
-
4
-
-
80053143413
-
Iso-genic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model
-
doi:10.1371/journal.pone.0025255
-
Ananiev, G., Williams, E. C., Li, H., and Chang, Q. (2011). Iso-genic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS ONE 6, e25255. doi:10.1371/journal.pone.0025255
-
(2011)
PLoS ONE
, vol.6
-
-
Ananiev, G.1
Williams, E.C.2
Li, H.3
Chang, Q.4
-
5
-
-
33947691631
-
Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo
-
Anderson, L., Burnstein, R. M., He, X., Luce, R., Furlong, R., Foltynie, T., Sykacek, P., Menon, D. K., and Cald-well, M. A. (2007). Gene expression changes in long term expanded human neural progenitor cells passaged by chopping lead to loss of neurogenic potential in vivo. Exp. Neurol. 204, 512-524.
-
(2007)
Exp. Neurol.
, vol.204
, pp. 512-524
-
-
Anderson, L.1
Burnstein, R.M.2
He, X.3
Luce, R.4
Furlong, R.5
Foltynie, T.6
Sykacek, P.7
Menon, D.K.8
Cald-well, M.A.9
-
6
-
-
79953881831
-
Highly efficient miRNA-mediated reprogram-ming of mouse and human somatic cells to pluripotency
-
Anokye-Danso, F., Trivedi, C. M., Chin-may, M., Juhr, D., Gupta, M., Cui, Z., Tian, Y., Zhang, Y., Yang, W., Gruber, P. J., Epstein, J. A., and Morrisey, E. E. (2011). Highly efficient miRNA-mediated reprogram-ming of mouse and human somatic cells to pluripotency. CellStem Cell 8, 376-388.
-
(2011)
CellStem Cell
, vol.8
, pp. 376-388
-
-
Anokye-Danso, F.1
Trivedi, C.M.2
Chin-may, M.3
Juhr, D.4
Gupta, M.5
Cui, Z.6
Tian, Y.7
Zhang, Y.8
Yang, W.9
Gruber, P.J.10
Epstein, J.A.11
Morrisey, E.E.12
-
7
-
-
5044234361
-
Chromosome 21 and Down syndrome: from genomics to pathophysiology
-
Antonarakis, S. E., Lyle, R., Dermitza-kis, E. T., Reymond, A., and Deutsch, S. (2004). Chromosome 21 and Down syndrome: from genomics to pathophysiology. Nat. Rev. Genet. 5, 725-738.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 725-738
-
-
Antonarakis, S.E.1
Lyle, R.2
Dermitza-kis, E.T.3
Reymond, A.4
Deutsch, S.5
-
8
-
-
41949134533
-
Generation of pluripotent stem cells from adult mouse liver and stomach cells
-
Aoi, T., Yae, K., Nakagawa, M., Ichisaka, T., Okita, K., Takahashi, K., Chiba, T., and Yamanaka, S. (2008). Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321, 699-702.
-
(2008)
Science
, vol.321
, pp. 699-702
-
-
Aoi, T.1
Yae, K.2
Nakagawa, M.3
Ichisaka, T.4
Okita, K.5
Takahashi, K.6
Chiba, T.7
Yamanaka, S.8
-
9
-
-
31144472414
-
Mutant huntingtin alters MAPK signaling pathways in PC12 and stri-atal cells: ERK1/2 protects against mutant huntingtin-associated toxicity
-
Apostol, B. L., Illes, K., Pallos, J., Bodai, L., Wu, J., Strand, A., Schweitzer, E. S., Olson, J. M., Kazantsev, A., Marsh, J. L., and Thompson, L. M. (2006). Mutant huntingtin alters MAPK signaling pathways in PC12 and stri-atal cells: ERK1/2 protects against mutant huntingtin-associated toxicity. Hum. Mol. Genet. 15, 273-285.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 273-285
-
-
Apostol, B.L.1
Illes, K.2
Pallos, J.3
Bodai, L.4
Wu, J.5
Strand, A.6
Schweitzer, E.S.7
Olson, J.M.8
Kazantsev, A.9
Marsh, J.L.10
Thompson, L.M.11
-
10
-
-
0037176537
-
Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study
-
Bahn, S., Mimmack, M., Ryan, M., Caldwell, M., Jauniaux, E., Starkey, M., Svendsen, C., and Emson, P. (2002). Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. Lancet 359, 310-315.
-
(2002)
Lancet
, vol.359
, pp. 310-315
-
-
Bahn, S.1
Mimmack, M.2
Ryan, M.3
Caldwell, M.4
Jauniaux, E.5
Starkey, M.6
Svendsen, C.7
Emson, P.8
-
11
-
-
33846879559
-
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo
-
Baker, D. E. C., Harrison, N. J., Maltby, E., Smith, K., Moore, H. D., Shaw, P. J., Heath, P. R., Holden, H., and Andrews, P. W (2007). Adaptation to culture of human embryonic stem cells and oncogenesis in vivo. Nat. Biotechnol. 25, 207-215.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 207-215
-
-
Baker, D.E.C.1
Harrison, N.J.2
Maltby, E.3
Smith, K.4
Moore, H.D.5
Shaw, P.J.6
Heath, P.R.7
Holden, H.8
Andrews, P.W.9
-
12
-
-
79960063073
-
Animal models: inside the minds of mice and men
-
Baker, M. (2011). Animal models: inside the minds of mice and men. Nature 475, 123-128.
-
(2011)
Nature
, vol.475
, pp. 123-128
-
-
Baker, M.1
-
13
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
-
Bar-Nur, O., Russ, H. A., Efrat, S., and Benvenisty, N. (2011). Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 9, 17-23.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
14
-
-
39149095271
-
PGD-derived human embryonic stem cell lines as a powerful tool for the study of human genetic disorders
-
Ben-Yosef, D., Malcov, M., and Eiges, R. (2008). PGD-derived human embryonic stem cell lines as a powerful tool for the study of human genetic disorders. Mol. Cell. Endocrinol. 282, 153-158.
-
(2008)
Mol. Cell. Endocrinol.
, vol.282
, pp. 153-158
-
-
Ben-Yosef, D.1
Malcov, M.2
Eiges, R.3
-
15
-
-
70450237623
-
A critical period in cortical interneuron neurogenesis in Down syndrome revealed by human neural progenitor cells
-
Bhattacharyya, A., Mcmillan, E., Chen, S. I., Wallace, K., and Svendsen, C. N. (2009). A critical period in cortical interneuron neurogenesis in Down syndrome revealed by human neural progenitor cells. Dev. Neurosci. 31, 497-510.
-
(2009)
Dev. Neurosci.
, vol.31
, pp. 497-510
-
-
Bhattacharyya, A.1
Mcmillan, E.2
Chen, S.I.3
Wallace, K.4
Svendsen, C.N.5
-
16
-
-
77958138433
-
Human embryonic stem cells as models for aneuploid chromosomal syndromes
-
Biancotti, J. C., Narwani, K., Buehler, N., Mandefro, B., Golan-Lev, T., Yanuka, O., Clark, A., Hill, D., Benvenisty, N., and Lavon, N. (2010). Human embryonic stem cells as models for aneuploid chromosomal syndromes. Stem Cells 28, 1530-1540.
-
(2010)
Stem Cells
, vol.28
, pp. 1530-1540
-
-
Biancotti, J.C.1
Narwani, K.2
Buehler, N.3
Mandefro, B.4
Golan-Lev, T.5
Yanuka, O.6
Clark, A.7
Hill, D.8
Benvenisty, N.9
Lavon, N.10
-
17
-
-
9444265273
-
Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants
-
Bieberich, E., Silva, J., Wang, G., Krishnamurthy, K., and Condie, B. G. (2004). Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J. CellBiol. 167, 723-734.
-
(2004)
J. CellBiol.
, vol.167
, pp. 723-734
-
-
Bieberich, E.1
Silva, J.2
Wang, G.3
Krishnamurthy, K.4
Condie, B.G.5
-
18
-
-
74849135201
-
The tumorigenicity of diploid and aneuploid human pluripotent stem cells
-
Blum, B., and Benvenisty, N. (2009). The tumorigenicity of diploid and aneuploid human pluripotent stem cells. Cell Cycle 8, 3822-3830.
-
(2009)
Cell Cycle
, vol.8
, pp. 3822-3830
-
-
Blum, B.1
Benvenisty, N.2
-
19
-
-
79952120621
-
Derivation of Huntington's disease-affected human embryonic stem cell lines
-
Bradley, C. K., Scott, H. A., Chami, O., Peura, T. T., Dumevska, B., Schmidt, U., and Stojanov, T. (2011). Derivation of Huntington's disease-affected human embryonic stem cell lines. Stem Cells Dev. 20, 495-502.
-
(2011)
Stem Cells Dev
, vol.20
, pp. 495-502
-
-
Bradley, C.K.1
Scott, H.A.2
Chami, O.3
Peura, T.T.4
Dumevska, B.5
Schmidt, U.6
Stojanov, T.7
-
20
-
-
79955884485
-
Modelling schizophrenia using human induced pluripotent stem cells
-
Brennand, K. J., Simone, A., Jou, J., Gelboin-Burkhart, C., Tran, N., San-gar, S., Li, Y., Mu, Y., Chen, G., Yu, D., Mccarthy, S., Sebat, J., and Gage, F. H. (2011). Modelling schizophrenia using human induced pluripotent stem cells. Nature 473, 221-225.
-
(2011)
Nature
, vol.473
, pp. 221-225
-
-
Brennand, K.J.1
Simone, A.2
Jou, J.3
Gelboin-Burkhart, C.4
Tran, N.5
San-gar, S.6
Li, Y.7
Mu, Y.8
Chen, G.9
Yu, D.10
Mccarthy, S.11
Sebat, J.12
Gage, F.H.13
-
21
-
-
70350223975
-
Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells
-
Buchholz, D. E., Hikita, S. T., Rowland, T. J., Friedrich, A. M., Hinman, C. R., Johnson, L. V., and Clegg, D. O. (2009). Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells 27, 2427-2434.
-
(2009)
Stem Cells
, vol.27
, pp. 2427-2434
-
-
Buchholz, D.E.1
Hikita, S.T.2
Rowland, T.J.3
Friedrich, A.M.4
Hinman, C.R.5
Johnson, L.V.6
Clegg, D.O.7
-
22
-
-
1842477467
-
Kary-otype of human ES cells during extended culture
-
Buzzard, J. J., Gough, N. M., Crook, J. M., and Colman, A. (2004). Kary-otype of human ES cells during extended culture. Nat. Biotechnol. 22, 381-382.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 381-382
-
-
Buzzard, J.J.1
Gough, N.M.2
Crook, J.M.3
Colman, A.4
-
23
-
-
84863230167
-
The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity
-
Camnasio, S., Carri, A. D., Lombardo, A., Grad, I., Mariotti, C., Castucci, A., Rozell, B., Riso, P. L., Cas-tiglioni, V., Zuccato, C., Rochon, C., Takashima, Y., Diaferia, G., Biunno, I., Gellera, C., Jaconi, M., Smith, A., Hovatta, O., Naldini, L., Di Donato, S., Feki, A., and Cattaneo, E. (2012). The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity. Neurobiol. Dis. 46, 41-51.
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 41-51
-
-
Camnasio, S.1
Carri, A.D.2
Lombardo, A.3
Grad, I.4
Mariotti, C.5
Castucci, A.6
Rozell, B.7
Riso, P.L.8
Cas-tiglioni, V.9
Zuccato, C.10
Rochon, C.11
Takashima, Y.12
Diaferia, G.13
Biunno, I.14
Gellera, C.15
Jaconi, M.16
Smith, A.17
Hovatta, O.18
Naldini, L.19
Di Donato, S.20
Feki, A.21
Cattaneo, E.22
more..
-
24
-
-
0032837298
-
In vitro expansion of a multipo-tent population of human neural progenitor cells
-
Carpenter, M. K., Cui, X., Hu, Z. Y., Jackson, J., Sherman, S., Seiger, A., and Wahlberg, L. U. (1999). In vitro expansion of a multipo-tent population of human neural progenitor cells. Exp. Neurol. 158, 265-278.
-
(1999)
Exp. Neurol.
, vol.158
, pp. 265-278
-
-
Carpenter, M.K.1
Cui, X.2
Hu, Z.Y.3
Jackson, J.4
Sherman, S.5
Seiger, A.6
Wahlberg, L.U.7
-
25
-
-
78049303170
-
Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes
-
Chamberlain, S. J., Chen, P. F., Ng, K. Y., Bourgois-Rocha, F., Lemtiri-Chlieh, E, Levine, E. S., and Lalande, M. (2010). Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader-Willi syndromes. Proc. Natl. Acad. Sci. U.S.A. 107, 17668-17673.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 17668-17673
-
-
Chamberlain, S.J.1
Chen, P.F.2
Ng, K.Y.3
Bourgois-Rocha, F.4
Lemtiri-Chlieh, E.5
Levine, E.S.6
Lalande, M.7
-
26
-
-
62149125434
-
Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
-
Chambers, S. M., Fasano, C. A., Papapetrou, E. P., Tomishima, M., Sadelain, M., and Studer, L. (2009). Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nat. Biotechnol. 27, 275-280.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 275-280
-
-
Chambers, S.M.1
Fasano, C.A.2
Papapetrou, E.P.3
Tomishima, M.4
Sadelain, M.5
Studer, L.6
-
27
-
-
81855206164
-
Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient
-
Chang, T., Zheng, W., Tsark, W., Bates, S., Huang, H., Lin, R. J., and Yee, J. K. (2011). Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient. Stem Cells 29, 2090-2093.
-
(2011)
Stem Cells
, vol.29
, pp. 2090-2093
-
-
Chang, T.1
Zheng, W.2
Tsark, W.3
Bates, S.4
Huang, H.5
Lin, R.J.6
Yee, J.K.7
-
28
-
-
81255210997
-
Modelling of Parkinson's disease in mice
-
Chesselet, M. F., and Richter, E (2011). Modelling of Parkinson's disease in mice. LancetNeurol. 10, 1108-1118.
-
(2011)
LancetNeurol
, vol.10
, pp. 1108-1118
-
-
Chesselet, M.F.1
Richter, E.2
-
29
-
-
79955602167
-
Isolation of MECP2-null Rett syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
-
Cheung, A. Y., Horvath, L. M., Grafo-datskaya, D., Pasceri, P., Weksberg, R., Hotta, A., Carrel, L., and Ellis, J. (2011). Isolation of MECP2-null Rett syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum. Mol. Genet. 20, 2103-2115.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2103-2115
-
-
Cheung, A.Y.1
Horvath, L.M.2
Grafo-datskaya, D.3
Pasceri, P.4
Weksberg, R.5
Hotta, A.6
Carrel, L.7
Ellis, J.8
-
30
-
-
79953048441
-
Integration-free induced pluripo-tent stem cells derived from schizo-phreniapatientswithaDISC1 mutation
-
Chiang, C. H., Su, Y., Wen, Z., Yorit-omo, N., Ross, C. A., Margolis, R. L., Song, H., and Ming, G. L. (2011). Integration-free induced pluripo-tent stem cells derived from schizo-phreniapatientswithaDISC1 mutation. Mol. Psychiatry 16, 358-360.
-
(2011)
Mol. Psychiatry
, vol.16
, pp. 358-360
-
-
Chiang, C.H.1
Su, Y.2
Wen, Z.3
Yorit-omo, N.4
Ross, C.A.5
Margolis, R.L.6
Song, H.7
Ming, G.L.8
-
31
-
-
70349485394
-
Motoneu-ron transplantation rescues the phe-notype of SMARD1 (spinal muscular atrophy with respiratory distress type 1)
-
Corti, S., Nizzardo, M., Nardini, M., Donadoni, C., Salani, S., Del Bo, R., Papadimitriou, D., Locatelli, F., Mezzina, N., Gianni, F., Bresolin, N., and Comi, G. P. (2009). Motoneu-ron transplantation rescues the phe-notype of SMARD1 (spinal muscular atrophy with respiratory distress type 1). J. Neurosci. 29, 11761-11771.
-
(2009)
J. Neurosci.
, vol.29
, pp. 11761-11771
-
-
Corti, S.1
Nizzardo, M.2
Nardini, M.3
Donadoni, C.4
Salani, S.5
Del Bo, R.6
Papadimitriou, D.7
Locatelli, F.8
Mezzina, N.9
Gianni, F.10
Bresolin, N.11
Comi, G.P.12
-
32
-
-
77249088647
-
Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice
-
Corti, S., Nizzardo, M., Nardini, M., Donadoni, C., Salani, S., Ronchi, D., Simone, C., Falcone, M., Papadimitriou, D., Locatelli, F., Mezzina, N., Gianni, F., Bresolin, N., and Comi, G. P. (2010). Embryonic stem cell-derived neural stem cells improve spinal muscular atrophy phenotype in mice. Brain 133, 465-481.
-
(2010)
Brain
, vol.133
, pp. 465-481
-
-
Corti, S.1
Nizzardo, M.2
Nardini, M.3
Donadoni, C.4
Salani, S.5
Ronchi, D.6
Simone, C.7
Falcone, M.8
Papadimitriou, D.9
Locatelli, F.10
Mezzina, N.11
Gianni, F.12
Bresolin, N.13
Comi, G.P.14
-
33
-
-
84860660444
-
Toward understanding Machado-Joseph disease
-
Costa, M. D. C., and Paulson, H. L. (2012). Toward understanding Machado-Joseph disease. Prog. Neu-robiol. 97, 239-257.
-
(2012)
Prog. Neu-robiol.
, vol.97
, pp. 239-257
-
-
Costa, M.D.C.1
Paulson, H.L.2
-
34
-
-
79954606776
-
Differentiation of induced pluripotent stem cells into functional oligodendrocytes
-
Czepiel, M., Balasubramaniyan, V., Schaafsma, W., Stancic, M., Mikkers, H., Huisman, C., Boddeke, E., and Copray, S. (2011). Differentiation of induced pluripotent stem cells into functional oligodendrocytes. Glia 59, 882-892.
-
(2011)
Glia
, vol.59
, pp. 882-892
-
-
Czepiel, M.1
Balasubramaniyan, V.2
Schaafsma, W.3
Stancic, M.4
Mikkers, H.5
Huisman, C.6
Boddeke, E.7
Copray, S.8
-
35
-
-
0242363670
-
Molecular pathways of neu-rodegeneration in Parkinson's disease
-
Dawson, T. M., and Dawson, V. L. (2003). Molecular pathways of neu-rodegeneration in Parkinson's disease. Science 302, 819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
36
-
-
81855175305
-
How to cross immunogenetic hurdles to human embryonic stem cell transplantation
-
De Rham, C., and Villard, J. (2011). How to cross immunogenetic hurdles to human embryonic stem cell transplantation. Semin. Immunopathol. 33, 525-534.
-
(2011)
Semin. Immunopathol.
, vol.33
, pp. 525-534
-
-
De Rham, C.1
Villard, J.2
-
37
-
-
44349152907
-
High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells
-
Desbordes, S. C., Placantonakis, D. G., Ciro, A., Socci, N. D., Lee, G., Djaballah, H., and Studer, L. (2008). High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells. Cell Stem Cell 2, 602-612.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 602-612
-
-
Desbordes, S.C.1
Placantonakis, D.G.2
Ciro, A.3
Socci, N.D.4
Lee, G.5
Djaballah, H.6
Studer, L.7
-
38
-
-
33745686121
-
Recovery from paral ysis in adult rats using embryonic stem cells
-
Deshpande, D. M., Kim, Y. S., Martinez, T., Carmen, J., Dike, S., Shats, I., Rubin, L. L., Drummond, J., Krish-nan, C., Hoke, A., Maragakis, N., Shefner, J., Rothstein, J. D., and Kerr, D. A. (2006). Recovery from paral ysis in adult rats using embryonic stem cells. Ann. Neurol. 60, 32-44.
-
(2006)
Ann. Neurol.
, vol.60
, pp. 32-44
-
-
Deshpande, D.M.1
Kim, Y.S.2
Martinez, T.3
Carmen, J.4
Dike, S.5
Shats, I.6
Rubin, L.L.7
Drummond, J.8
Krish-nan, C.9
Hoke, A.10
Maragakis, N.11
Shefner, J.12
Rothstein, J.D.13
Kerr, D.A.14
-
39
-
-
0035007860
-
A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis ALS riluzole-tocopherol Study Group
-
Desnuelle, C., Dib, M., Garrel, C., and Favier, A. (2001). A double-blind, placebo-controlled randomized clinical trial of alpha-tocopherol (vitamin E) in the treatment of amyotrophic lateral sclerosis. ALS riluzole-tocopherol Study Group. Amyotroph. Lateral Scler. Other Motor Neuron Disord. 2, 9-18.
-
(2001)
Amyotroph. Lateral Scler. Other Motor Neuron Disord.
, vol.2
, pp. 9-18
-
-
Desnuelle, C.1
Dib, M.2
Garrel, C.3
Favier, A.4
-
40
-
-
80052419902
-
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
-
Devine, M. J., Ryten, M., Vodicka, P., Thomson, A. J., Burdon, T., Houlden, H., Cavaleri, F., Nagano, M., Drummond, N. J., Taanman, J. W., Schapira, A. H., Gwinn, K., Hardy, J., Lewis, P. A., and Kunath, T. (2011). Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nat. Commun. 2, 440.
-
(2011)
Nat. Commun.
, vol.2
, pp. 440
-
-
Devine, M.J.1
Ryten, M.2
Vodicka, P.3
Thomson, A.J.4
Burdon, T.5
Houlden, H.6
Cavaleri, F.7
Nagano, M.8
Drummond, N.J.9
Taanman, J.W.10
Schapira, A.H.11
Gwinn, K.12
Hardy, J.13
Lewis, P.A.14
Kunath, T.15
-
41
-
-
56549096129
-
Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation
-
Di Giorgio, E P., Boulting, G. L., Bobrowicz, S., and Eggan, K. C. (2008). Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation. Cell Stem Cell 3, 637-648.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 637-648
-
-
Di Giorgio, E.P.1
Boulting, G.L.2
Bobrowicz, S.3
Eggan, K.C.4
-
42
-
-
33751119892
-
Translating preclinical insights into effective human trials in ALS
-
Dibernardo, A. B., and Cudkowicz, M. E. (2006). Translating preclinical insights into effective human trials in ALS. Biochim. Biophys. Acta 1762, 1139-1149.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1139-1149
-
-
Dibernardo, A.B.1
Cudkowicz, M.E.2
-
43
-
-
50149098605
-
Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
-
Dimos, J. T., Rodolfa, K. T., Niakan, K. K., Weisenthal, L. M., Mitsumoto, H., Chung, W., Croft, G. F., Saphier, G., Leibel, R., Go land, R., Wichterle, H., Henderson, C. E., and Eggan, K. (2008). Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 321, 1218-1221.
-
(2008)
Science
, vol.321
, pp. 1218-1221
-
-
Dimos, J.T.1
Rodolfa, K.T.2
Niakan, K.K.3
Weisenthal, L.M.4
Mitsumoto, H.5
Chung, W.6
Croft, G.F.7
Saphier, G.8
Leibel, R.9
Go land, R.10
Wichterle, H.11
Henderson, C.E.12
Eggan, K.13
-
44
-
-
0348103716
-
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells
-
Draper, J. S., Smith, K., Gokhale, P., Moore, H. D., Maltby, E., Johnson, J., Meisner, L., Zwaka, T. P., Thomson, J.A., and Andrews, P.W. (2004). Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells. Nat. Biotechnol. 22, 53-54.
-
(2004)
Nat. Biotechnol.
, vol.22
, pp. 53-54
-
-
Draper, J.S.1
Smith, K.2
Gokhale, P.3
Moore, H.D.4
Maltby, E.5
Johnson, J.6
Meisner, L.7
Zwaka, T.P.8
Thomson, J.A.9
Andrews, P.W.10
-
45
-
-
34748866686
-
Signaling pathways in cancer and embryonic stem cells
-
Dreesen, O., and Brivanlou, A. H. (2007). Signaling pathways in cancer and embryonic stem cells. Stem Cell Rev. 3, 7-17.
-
(2007)
Stem Cell Rev
, vol.3
, pp. 7-17
-
-
Dreesen, O.1
Brivanlou, A.H.2
-
46
-
-
58249110796
-
Induced pluripotent stem cells from a spinal muscular atrophy patient
-
Ebert, A. D., Yu, J., Rose, E E, Mat-tis, V. B., Lorson, C. L., Thomson, J. A., and Svendsen, C. N. (2009). Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277-280.
-
(2009)
Nature
, vol.457
, pp. 277-280
-
-
Ebert, A.D.1
Yu, J.2
Rose, E.E.3
Mat-tis, V.B.4
Lorson, C.L.5
Thomson, J.A.6
Svendsen, C.N.7
-
47
-
-
35848937244
-
Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplanta-tion genetically diagnosed embryos
-
Eiges, R., Urbach, A., Malcov, M., Frumkin, T., Schwartz, T., Amit, A., Yaron, Y., Eden, A., Yanuka, O., Ben-venisty,N.,andBen-Yosef, D. (2007). Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplanta-tion genetically diagnosed embryos. Cell Stem Cell 1, 568-577.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 568-577
-
-
Eiges, R.1
Urbach, A.2
Malcov, M.3
Frumkin, T.4
Schwartz, T.5
Amit, A.6
Yaron, Y.7
Eden, A.8
Yanuka, O.9
Ben-venisty, N.10
Ben-Yosef, D.11
-
48
-
-
54949102049
-
Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals
-
Eiraku, M., Watanabe, K., Matsuo-Takasaki, M., Kawada, M., Yone-mura, S., Matsumura, M.,Wataya, T., Nishiyama, A., Muguruma, K., and Sasai, Y. (2008). Self-organized formation of polarized cortical tissues from ESCs and its active manipulation by extrinsic signals. Cell Stem Cell 3, 519-532.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 519-532
-
-
Eiraku, M.1
Watanabe, K.2
Matsuo-Takasaki, M.3
Kawada, M.4
Yone-mura, S.5
Matsumura, M.6
Wataya, T.7
Nishiyama, A.8
Muguruma, K.9
Sasai, Y.10
-
49
-
-
0035878561
-
Chromosome 1 loci in Finnish schizophrenia families
-
Ekelund, J., Hovatta, I., Parker, A., Pau-nio, T., Varilo, T., Martin, R., Suho-nen, J., Ellonen, P., Chan, G., Sin-sheimer, J. S., Sobel, E., Juvonen, H., Arajärvi, R., Partonen, T., Suvisaari, J., Lönnqvist, J., Meyer, J., and Pelto-nen, L. (2001). Chromosome 1 loci in Finnish schizophrenia families. Hum. Mol. Genet. 10, 1611-1617.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1611-1617
-
-
Ekelund, J.1
Hovatta, I.2
Parker, A.3
Pau-nio, T.4
Varilo, T.5
Martin, R.6
Suho-nen, J.7
Ellonen, P.8
Chan, G.9
Sin-sheimer, J.S.10
Sobel, E.11
Juvonen, H.12
Arajärvi, R.13
Partonen, T.14
Suvisaari, J.15
Lönnqvist, J.16
Meyer, J.17
Pelto-nen, L.18
-
50
-
-
0019826665
-
Establishment in culture of pluripotential cells from mouse embryos
-
Evans, M. J., and Kaufman, M. H. (1981). Establishment in culture of pluripotential cells from mouse embryos. Nature 292, 154-156.
-
(1981)
Nature
, vol.292
, pp. 154-156
-
-
Evans, M.J.1
Kaufman, M.H.2
-
51
-
-
47549096256
-
Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells
-
Evans, P. M., and Liu, C. (2008). Roles of Krüppel-like factor 4 in normal homeostasis, cancer and stem cells. Acta Biochim. Biophys. Sin. (Shanghai) 40, 554-564.
-
(2008)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.40
, pp. 554-564
-
-
Evans, P.M.1
Liu, C.2
-
52
-
-
62949220231
-
Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells
-
Feng, B., Ng, J. H., Heng, J. C. D., and Ng, H. H. (2009). Molecules that promote or enhance reprogramming of somatic cells to induced pluripotent stem cells. Cell Stem Cell 4, 301-312.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 301-312
-
-
Feng, B.1
Ng, J.H.2
Heng, J.C.D.3
Ng, H.H.4
-
53
-
-
80755163102
-
Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis
-
Ferraiuolo, L., Kirby, J., Grierson, A. J., Sendtner, M., and Shaw, P. J. (2011). Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis. Nat. Rev. Neurol. 7, 616-630.
-
(2011)
Nat. Rev. Neurol.
, vol.7
, pp. 616-630
-
-
Ferraiuolo, L.1
Kirby, J.2
Grierson, A.J.3
Sendtner, M.4
Shaw, P.J.5
-
54
-
-
79959955179
-
Retinitis pig-mentosa: genes and disease mechanisms
-
Ferrari, S., Di Iorio, E., Barbaro, V., Ponzin, D., Sorrentino, E S., and Parmeggiani, F. (2011). Retinitis pig-mentosa: genes and disease mechanisms. Curr. Genomics 12, 238-249.
-
(2011)
Curr. Genomics
, vol.12
, pp. 238-249
-
-
Ferrari, S.1
Di Iorio, E.2
Barbaro, V.3
Ponzin, D.4
Sorrentino, E.S.5
Parmeggiani, F.6
-
55
-
-
77953216242
-
General aspects and neuropathology of X-linked adrenoleukodystrophy
-
Ferrer, I., Aubourg, P., and Pujol, A. (2010). General aspects and neuropathology of X-linked adrenoleukodystrophy. Brain Pathol. 20, 817-830.
-
(2010)
Brain Pathol
, vol.20
, pp. 817-830
-
-
Ferrer, I.1
Aubourg, P.2
Pujol, A.3
-
56
-
-
67649995736
-
Subretinal transplantation of fore-brain progenitor cells in nonhuman primates: survival and intact retinal function
-
Francis, P. J., Wang, S., Zhang, Y., Brown, A., Hwang, T., Mcfarland, T. J., Jeffrey, B. G., Lu, B., Wright, L., Appukuttan, B., Wilson, D. J., Stout, J. T., Neuringer, M., Gamm, D. M., and Lund, R. D. (2009). Subretinal transplantation of fore-brain progenitor cells in nonhuman primates: survival and intact retinal function. Invest. Ophthalmol. Vis. Sci. 50, 3425-3431.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 3425-3431
-
-
Francis, P.J.1
Wang, S.2
Zhang, Y.3
Brown, A.4
Hwang, T.5
Mcfarland, T.J.6
Jeffrey, B.G.7
Lu, B.8
Wright, L.9
Appukuttan, B.10
Wilson, D.J.11
Stout, J.T.12
Neuringer, M.13
Gamm, D.M.14
Lund, R.D.15
-
57
-
-
77952094754
-
Human embryonic stem cells carrying mutations for severe genetic disorders
-
Frumkin, T., Malcov, M., Telias, M., Gold, V., Schwartz, T., Azem, F., Amit, A., Yaron, Y., and Ben-Yosef, D. (2010). Human embryonic stem cells carrying mutations for severe genetic disorders. In vitro Cell. Dev. Biol. Anim. 46, 327-336.
-
(2010)
In vitro Cell. Dev. Biol. Anim.
, vol.46
, pp. 327-336
-
-
Frumkin, T.1
Malcov, M.2
Telias, M.3
Gold, V.4
Schwartz, T.5
Azem, F.6
Amit, A.7
Yaron, Y.8
Ben-Yosef, D.9
-
58
-
-
33745001244
-
Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation
-
Fukuda, H., Takahashi, J., Watanabe, K., Hayashi, H., Morizane, A., Koy-anagi, M., Sasai, Y., and Hashimoto, N. (2006). Fluorescence-activated cell sorting-based purification of embryonic stem cell-derived neural precursors averts tumor formation after transplantation. Stem Cells 24, 763-771.
-
(2006)
Stem Cells
, vol.24
, pp. 763-771
-
-
Fukuda, H.1
Takahashi, J.2
Watanabe, K.3
Hayashi, H.4
Morizane, A.5
Koy-anagi, M.6
Sasai, Y.7
Hashimoto, N.8
-
59
-
-
84860859564
-
Modeling human neurodegenerative diseases in trans-genic systems
-
Gama Sosa, M., De Gasperi, R., and Elder, G. (2012). Modeling human neurodegenerative diseases in trans-genic systems. Hum. Genet. 131, 535-563.
-
(2012)
Hum. Genet.
, vol.131
, pp. 535-563
-
-
Gama Sosa, M.1
De Gasperi, R.2
Elder, G.3
-
60
-
-
36148963069
-
Protection of visual functions by human neural progenitors in a rat model of retinal disease
-
doi:10.1371/journal.pone.0000338
-
Gamm, D. M., Wang, S., Lu, B., Gir-man, S., Holmes, T., Bischoff, N., Shearer, R. L., Sauvé, Y., Capowski, E., Svendsen, C. N., and Lund, R. D. (2007). Protection of visual functions by human neural progenitors in a rat model of retinal disease. PLoS ONE 2, e338. doi:10.1371/journal.pone.0000338
-
(2007)
PLoS ONE
, vol.2
-
-
Gamm, D.M.1
Wang, S.2
Lu, B.3
Gir-man, S.4
Holmes, T.5
Bischoff, N.6
Shearer, R.L.7
Sauvé, Y.8
Capowski, E.9
Svendsen, C.N.10
Lund, R.D.11
-
61
-
-
52149102948
-
An intrinsic mechanism of corticogenesis from embryonic stem cells
-
Gaspard, N., Bouschet, T., Hourez, R., Dimidschstein, J., Naeije, G., Van Den Ameele, J., Espuny-Camacho, I., Herpoel, A., Passante, L., Schiff-mann, S. N., Gaillard, A., and Van-derhaeghen, P. (2008). An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature 455, 351-357.
-
(2008)
Nature
, vol.455
, pp. 351-357
-
-
Gaspard, N.1
Bouschet, T.2
Hourez, R.3
Dimidschstein, J.4
Naeije, G.5
Van Den Ameele, J.6
Espuny-Camacho, I.7
Herpoel, A.8
Passante, L.9
Schiff-mann, S.N.10
Gaillard, A.11
Van-derhaeghen, P.12
-
62
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass, C. K., Saijo, K., Winner, B., Mar-chetto, M. C., and Gage, E H. (2010). Mechanisms underlying inflammation in neurodegeneration. Cell 140, 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Mar-chetto, M.C.4
Gage, E.H.5
-
63
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore, A., Li, Z., Fung, H. L., Young, J. E.,Agarwal,S.,Antosiewicz-Bourget, J., Canto, I., Giorgetti, A., Israel, M. A., Kiskinis, E., Lee, J. H., Loh, Y. H., Manos, P. D., Montserrat, N., Panopoulos, A. D., Ruiz, S., Wilbert, M. L., Yu, J., Kirkness, E. F., Bel-monte, J. C. I., Rossi, D. J., Thomson, J. A., Eggan, K., Daley, G. Q., Goldstein, L. S. B., and Zhang, K. (2011). Somatic coding mutations in human induced pluripotent stem cells. Nature 471, 63-67.
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.L.3
Young, J.E.4
Agarwal, S.5
Antosiewicz-Bourget, J.6
Canto, I.7
Giorgetti, A.8
Israel, M.A.9
Kiskinis, E.10
Lee, J.H.11
Loh, Y.H.12
Manos, P.D.13
Montserrat, N.14
Panopoulos, A.D.15
Ruiz, S.16
Wilbert, M.L.17
Yu, J.18
Kirkness, E.F.19
Bel-monte, J.C.I.20
Rossi, D.J.21
Thomson, J.A.22
Eggan, K.23
Daley, G.Q.24
Goldstein, L.S.B.25
Zhang, K.26
more..
-
64
-
-
84857130181
-
NANOG priming before full reprogramming may generate germ cell tumors
-
Grad, I., Hibaoui, Y., Jaconi, M., Chicha, L., Bergström-Tengzelius, R., Sailani, M. R., Pelte, M. F., Dahoun, S., Mit-siadis, T. A., Töhönen, V., Bouil-laguet, S., Antonarakis, S. E., Kere, J., Zucchelli, M., Hovatta, O., and Feki, A. (2011). NANOG priming before full reprogramming may generate germ cell tumors. Eur. Cell Mater. 22, 258-274.
-
(2011)
Eur. Cell Mater.
, vol.22
, pp. 258-274
-
-
Grad, I.1
Hibaoui, Y.2
Jaconi, M.3
Chicha, L.4
Bergström-Tengzelius, R.5
Sailani, M.R.6
Pelte, M.F.7
Dahoun, S.8
Mit-siadis, T.A.9
Töhönen, V.10
Bouil-laguet, S.11
Antonarakis, S.E.12
Kere, J.13
Zucchelli, M.14
Hovatta, O.15
Feki, A.16
-
65
-
-
80052783545
-
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
-
Haidet-Phillips, A. M., Hester, M. E., Miranda, C. J., Meyer, K., Braun, L., Frakes, A., Song, S., Likhite, S., Murtha, M. J., Foust, K. D., Rao, M., Eagle, A., Kammesheidt, A., Christensen, A., Mendell, J. R., Burghes, A. H. M., and Kaspar, B. K. (2011). Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat. Biotechnol. 29, 824-828.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 824-828
-
-
Haidet-Phillips, A.M.1
Hester, M.E.2
Miranda, C.J.3
Meyer, K.4
Braun, L.5
Frakes, A.6
Song, S.7
Likhite, S.8
Murtha, M.J.9
Foust, K.D.10
Rao, M.11
Eagle, A.12
Kammesheidt, A.13
Christensen, A.14
Mendell, J.R.15
Burghes, A.H.M.16
Kaspar, B.K.17
-
66
-
-
71449109765
-
Direct cell repro-gramming is a stochastic process amenable to acceleration
-
Hanna, J., Saha, K., Pando, B., Van Zon, J., Lengner, C. J., Creyghton, M. P., Van Oudenaarden, A., and Jaenisch, R. (2009). Direct cell repro-gramming is a stochastic process amenable to acceleration. Nature 462, 595-601.
-
(2009)
Nature
, vol.462
, pp. 595-601
-
-
Hanna, J.1
Saha, K.2
Pando, B.3
Van Zon, J.4
Lengner, C.J.5
Creyghton, M.P.6
Van Oudenaarden, A.7
Jaenisch, R.8
-
67
-
-
78149487692
-
Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues
-
Hanna, J. H., Saha, K., and Jaenisch, R. (2010). Pluripotency and cellular reprogramming: facts, hypotheses, unresolved issues. Cell 143, 508-525.
-
(2010)
Cell
, vol.143
, pp. 508-525
-
-
Hanna, J.H.1
Saha, K.2
Jaenisch, R.3
-
68
-
-
77957905690
-
Genetic analysis of pathways to Parkinson disease
-
Hardy, J. (2010). Genetic analysis of pathways to Parkinson disease. Neuron 68, 201-206.
-
(2010)
Neuron
, vol.68
, pp. 201-206
-
-
Hardy, J.1
-
69
-
-
77957670482
-
Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
-
Hargus, G., Cooper, O., Deleidi, M., Levy, A., Lee, K., Marlow, E., Yow, A., Soldner, F., Hockemeyer, D., Hallett, P. J., Osborn, T., Jaenisch, R., and Isacson, O. (2010). Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc. Natl. Acad. Sci. U.S.A. 107, 15921-15926.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 15921-15926
-
-
Hargus, G.1
Cooper, O.2
Deleidi, M.3
Levy, A.4
Lee, K.5
Marlow, E.6
Yow, A.7
Soldner, F.8
Hockemeyer, D.9
Hallett, P.J.10
Osborn, T.11
Jaenisch, R.12
Isacson, O.13
-
70
-
-
2342472526
-
Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats
-
Harper, J. M., Krishnan, C., Darman, J. S., Deshpande, D. M., Peck, S., Shats, I., Backovic, S., Rothstein, J. D., and Kerr, D. A. (2004). Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats. Proc. Natl. Acad. Sci. U.S.A. 101, 7123-7128.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7123-7128
-
-
Harper, J.M.1
Krishnan, C.2
Darman, J.S.3
Deshpande, D.M.4
Peck, S.5
Shats, I.6
Backovic, S.7
Rothstein, J.D.8
Kerr, D.A.9
-
71
-
-
34247188473
-
Telomere and telomerase in stem cells
-
Hiyama, E., and Hiyama, K. (2007). Telomere and telomerase in stem cells. Br. J. Cancer 96, 1020-1024.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 1020-1024
-
-
Hiyama, E.1
Hiyama, K.2
-
72
-
-
18844392836
-
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues
-
Hochedlinger, K., Yamada, Y., Beard, C., and Jaenisch, R. (2005). Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues. Cell 121, 465-477.
-
(2005)
Cell
, vol.121
, pp. 465-477
-
-
Hochedlinger, K.1
Yamada, Y.2
Beard, C.3
Jaenisch, R.4
-
73
-
-
70249114821
-
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases
-
Hockemeyer, D., Soldner, F., Beard, C., Gao, Q., Mitalipova, M., Dekelver, R. C., Katibah, G. E., Amora, R., Boydston, E. A., Zeitler, B., Meng, X., Miller, J. C., Zhang, L., Rebar, E. J., Gregory, P. D., Urnov, F. D., and Jaenisch, R. (2009). Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases. Nat. Biotechnol. 27, 851-857.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 851-857
-
-
Hockemeyer, D.1
Soldner, F.2
Beard, C.3
Gao, Q.4
Mitalipova, M.5
Dekelver, R.C.6
Katibah, G.E.7
Amora, R.8
Boydston, E.A.9
Zeitler, B.10
Meng, X.11
Miller, J.C.12
Zhang, L.13
Rebar, E.J.14
Gregory, P.D.15
Urnov, F.D.16
Jaenisch, R.17
-
74
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer, D., Wang, H., Kiani, S., Lai, C. S., Gao, Q., Cassady, J. P., Cost, G. J., Zhang, L., Santiago, Y., Miller, J. C., Zeitler, B., Cherone, J. M., Meng, X., Hinkley, S. J., Rebar, E. J., Gregory, P. D., Urnov, F. D., and Jaenisch, R. (2011). Genetic engineering of human pluripotent cells using TALE nucleases. Nat. Biotechnol. 29, 731-734.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
Cost, G.J.7
Zhang, L.8
Santiago, Y.9
Miller, J.C.10
Zeitler, B.11
Cherone, J.M.12
Meng, X.13
Hinkley, S.J.14
Rebar, E.J.15
Gregory, P.D.16
Urnov, F.D.17
Jaenisch, R.18
-
75
-
-
77956520627
-
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes
-
doi:10.1371/journal.pone.0010263
-
Hovatta, O., Jaconi, M., Töhönen, V, Bena, F., Gimelli, S., Bosman, A., Holm, F., Wyder, S., Zdob-nov, E. M., Irion, O., Andrews, P. W., Antonarakis, S. E., Zuc-chelli, M., Kere, J., and Feki, A. (2010). A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes. PLoS ONE 5, e10263. doi:10.1371/journal.pone.0010263
-
(2010)
PLoS ONE
, vol.5
-
-
Hovatta, O.1
Jaconi, M.2
Töhönen, V.3
Bena, F.4
Gimelli, S.5
Bosman, A.6
Holm, F.7
Wyder, S.8
Zdob-nov, E.M.9
Irion, O.10
Andrews, P.W.11
Antonarakis, S.E.12
Zuc-chelli, M.13
Kere, J.14
Feki, A.15
-
76
-
-
73949130191
-
Differentiation of human oligodendrocytes from pluripotent stem cells
-
Hu, B. Y., Du, Z. W., and Zhang, S. C. (2009). Differentiation of human oligodendrocytes from pluripotent stem cells. Nat. Protoc. 4, 1614-1622.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1614-1622
-
-
Hu, B.Y.1
Du, Z.W.2
Zhang, S.C.3
-
77
-
-
77749279749
-
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
-
Hu, B. Y., Weick, J. P., Yu, J., Ma, L. X., Zhang, X. Q., Thomson, J. A., and Zhang, S. C. (2010). Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency. Proc. Natl. Acad. Sci. U.S.A. 107, 4335-4340.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 4335-4340
-
-
Hu, B.Y.1
Weick, J.P.2
Yu, J.3
Ma, L.X.4
Zhang, X.Q.5
Thomson, J.A.6
Zhang, S.C.7
-
78
-
-
70249133666
-
Differentiation of spinal motor neurons from pluripotent human stem cells
-
Hu, B. Y., and Zhang, S. C. (2009). Differentiation of spinal motor neurons from pluripotent human stem cells. Nat. Protoc. 4, 1295-1304.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1295-1304
-
-
Hu, B.Y.1
Zhang, S.C.2
-
79
-
-
77953089981
-
Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs
-
Hu, B. Y., and Zhang, S. C. (2010). Directed differentiation of neural-stem cells and subtype-specific neurons from hESCs. MethodsMol. Biol. 636, 123-137.
-
(2010)
MethodsMol. Biol.
, vol.636
, pp. 123-137
-
-
Hu, B.Y.1
Zhang, S.C.2
-
80
-
-
55749104227
-
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
-
Huangfu, D., Osafune, K., Maehr, R., Guo, W., Eijkelenboom, A., Chen, S., Muhlestein, W., and Melton, D.A. (2008). Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2. Nat. Biotech. 26, 1269-1275.
-
(2008)
Nat. Biotech.
, vol.26
, pp. 1269-1275
-
-
Huangfu, D.1
Osafune, K.2
Maehr, R.3
Guo, W.4
Eijkelenboom, A.5
Chen, S.6
Muhlestein, W.7
Melton, D.A.8
-
81
-
-
79952126043
-
Copy number variation and selection during reprogramming to pluripotency
-
Hussein, S. M., Batada, N. N., Vuoristo, S., Ching, R. W., Autio, R., Narva, E., Ng, S., Sourour, M., Hamalainen, R., Olsson, C., Lundin, K., Mikkola, M., Trokovic, R., Peitz, M., Brustle, O., Bazett-Jones, D. P., Alitalo, K., Lah-esmaa, R., Nagy, A., and Otonkoski, T. (2011). Copy number variation and selection during reprogramming to pluripotency. Nature 471, 58-62.
-
(2011)
Nature
, vol.471
, pp. 58-62
-
-
Hussein, S.M.1
Batada, N.N.2
Vuoristo, S.3
Ching, R.W.4
Autio, R.5
Narva, E.6
Ng, S.7
Sourour, M.8
Hamalainen, R.9
Olsson, C.10
Lundin, K.11
Mikkola, M.12
Trokovic, R.13
Peitz, M.14
Brustle, O.15
Bazett-Jones, D.P.16
Alitalo, K.17
Lah-esmaa, R.18
Nagy, A.19
Otonkoski, T.20
more..
-
82
-
-
79955464098
-
The use of induced pluripotent stem cells in drug development
-
Inoue, H., and Yamanaka, S. (2011). The use of induced pluripotent stem cells in drug development. Clin. Pharmacol. Ther. 89, 655-661.
-
(2011)
Clin. Pharmacol. Ther.
, vol.89
, pp. 655-661
-
-
Inoue, H.1
Yamanaka, S.2
-
83
-
-
79960884465
-
Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges
-
Israel, M., and Goldstein, L. S. (2011). Capturing Alzheimer's disease genomes with induced pluripotent stem cells: prospects and challenges. Genome Med. 3, 49.
-
(2011)
Genome Med
, vol.3
, pp. 49
-
-
Israel, M.1
Goldstein, L.S.2
-
84
-
-
84856956771
-
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells
-
Israel, M. A., Yuan, S. H., Bardy, C., Reyna, S. M., Mu, Y., Herrera, C., Hefferan, M. P., Van Gorp, S., Nazor, K. L., Boscolo, F. S., Carson, C. T., Laurent, L. C., Marsala, M., Gage, F. H., Remes, A. M., Koo, E. H., and Goldstein, L. S. (2012). Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. Nature 482, 216-220.
-
(2012)
Nature
, vol.482
, pp. 216-220
-
-
Israel, M.A.1
Yuan, S.H.2
Bardy, C.3
Reyna, S.M.4
Mu, Y.5
Herrera, C.6
Hefferan, M.P.7
Van Gorp, S.8
Nazor, K.L.9
Boscolo, F.S.10
Carson, C.T.11
Laurent, L.C.12
Marsala, M.13
Gage, F.H.14
Remes, A.M.15
Koo, E.H.16
Goldstein, L.S.17
-
85
-
-
39149130361
-
Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming
-
Jaenisch, R., and Young, R. (2008). Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming. Cell 132, 567-582.
-
(2008)
Cell
, vol.132
, pp. 567-582
-
-
Jaenisch, R.1
Young, R.2
-
86
-
-
80052579389
-
Induced pluripotent stem cell models from X-linked adrenoleukody-strophy patients
-
Jang, J., Kang, H. C., Kim, H. S., Kim, J. Y., Huh, Y. J., Kim, D. S., Yoo, J. E., Lee, J. A., Lim, B., Lee, J., Yoon, T. M., Park, I. H., Hwang, D. Y., Daley, G. Q., and Kim, D. W. (2011). Induced pluripotent stem cell models from X-linked adrenoleukody-strophy patients. Ann. Neurol. 70, 402-409.
-
(2011)
Ann. Neurol.
, vol.70
, pp. 402-409
-
-
Jang, J.1
Kang, H.C.2
Kim, H.S.3
Kim, J.Y.4
Huh, Y.J.5
Kim, D.S.6
Yoo, J.E.7
Lee, J.A.8
Lim, B.9
Lee, J.10
Yoon, T.M.11
Park, I.H.12
Hwang, D.Y.13
Daley, G.Q.14
Kim, D.W.15
-
87
-
-
79951849153
-
Modeling retinal degeneration using patient-specific induced pluripotent stem cells
-
doi:10.1371/journal.pone.0017084
-
Jin, Z. B., Okamoto, S., Osakada, F., Homma, K., Assawachananont, J., Hirami, Y., Iwata, T., and Takahashi, M. (2011). Modeling retinal degeneration using patient-specific induced pluripotent stem cells. PLoS ONE 6, e 17084. doi:10.1371/journal.pone.0017084
-
(2011)
PLoS ONE
, vol.6
-
-
Jin, Z.B.1
Okamoto, S.2
Osakada, F.3
Homma, K.4
Assawachananont, J.5
Hirami, Y.6
Iwata, T.7
Takahashi, M.8
-
88
-
-
20144387207
-
Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations
-
Kachergus, J., Mata, I. F., Hulihan, M., Taylor, J. P., Lincoln, S., Aasly, J., Gibson, J. M., Ross, O. A., Lynch, T., Wiley, J., Payami, H., Nutt, J., Maraganore, D. M., Czyzewski, K., Styczynska, M., Wszolek, Z. K., Far-rer, M. J., and Toft, M. (2005). Identification of a novel LRRK2 mutation linked to autosomal dominant parkinsonism: evidence of a common founder across European populations. Am. J. Hum. Genet. 76, 672-680.
-
(2005)
Am. J. Hum. Genet.
, vol.76
, pp. 672-680
-
-
Kachergus, J.1
Mata, I.F.2
Hulihan, M.3
Taylor, J.P.4
Lincoln, S.5
Aasly, J.6
Gibson, J.M.7
Ross, O.A.8
Lynch, T.9
Wiley, J.10
Payami, H.11
Nutt, J.12
Maraganore, D.M.13
Czyzewski, K.14
Styczynska, M.15
Wszolek, Z.K.16
Far-rer, M.J.17
Toft, M.18
-
89
-
-
64749111225
-
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
-
Kaji, K., Norrby, K., Paca, A., Mileikovsky, M., Mohseni, P., and Woltjen, K. (2009). Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458, 771-775.
-
(2009)
Nature
, vol.458
, pp. 771-775
-
-
Kaji, K.1
Norrby, K.2
Paca, A.3
Mileikovsky, M.4
Mohseni, P.5
Woltjen, K.6
-
90
-
-
18644384444
-
Human embryonic stem cell-derived oligo-dendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury
-
Keirstead, H. S., Nistor, G., Bernal, G., Totoiu, M., Cloutier, F., Sharp, K., and Steward, O. (2005). Human embryonic stem cell-derived oligo-dendrocyte progenitor cell transplants remyelinate and restore locomotion after spinal cord injury. J. Neurosci. 25, 4694-4705.
-
(2005)
J. Neurosci.
, vol.25
, pp. 4694-4705
-
-
Keirstead, H.S.1
Nistor, G.2
Bernal, G.3
Totoiu, M.4
Cloutier, F.5
Sharp, K.6
Steward, O.7
-
91
-
-
18844396119
-
Embryonic stem cell differentiation: emergence of a new era in biology and medicine
-
Keller, G. (2005). Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev. 19, 1129-1155.
-
(2005)
Genes Dev
, vol.19
, pp. 1129-1155
-
-
Keller, G.1
-
92
-
-
66049143859
-
Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins
-
Kim, D., Kim, C. H., Moon, J. I., Chung, Y. G., Chang, M. Y., Han, B. S., Ko, S., Yang, E., Cha, K. Y., Lanza, R., and Kim, K. S. (2009). Generation of human induced pluripotent stem cells by direct delivery of reprogramming proteins. Cell Stem Cell 4, 472-476.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.H.2
Moon, J.I.3
Chung, Y.G.4
Chang, M.Y.5
Han, B.S.6
Ko, S.7
Yang, E.8
Cha, K.Y.9
Lanza, R.10
Kim, K.S.11
-
93
-
-
79952601242
-
Investigating synapse formation and function using human pluripotent stem cell-derived neurons
-
Kim, J. E., O'Sullivan, M. L., Sanchez, C. A., Hwang, M., Israel, M. A., Bren-nand, K., Deerinck, T. J., Goldstein, L. S., Gage, F. H., Ellisman, M. H., and Ghosh, A. (2011). Investigating synapse formation and function using human pluripotent stem cell-derived neurons. Proc. Natl. Acad. Sci. U.S.A. 108, 3005-3010.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 3005-3010
-
-
Kim, J.E.1
O'Sullivan, M.L.2
Sanchez, C.A.3
Hwang, M.4
Israel, M.A.5
Bren-nand, K.6
Deerinck, T.J.7
Goldstein, L.S.8
Gage, F.H.9
Ellisman, M.H.10
Ghosh, A.11
-
94
-
-
83255177149
-
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
-
Kim, K., Zhao, R., Doi, A., Ng, K., Unternaehrer, J., Cahan, P., Hong-guang, H., Loh, Y H., Aryee, M. J., Lensch, M. W., Li, H., Collins, J. J., Feinberg, A. P., and Daley, G. Q. (2011). Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat. Biotechnol. 29, 1117-1119.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 1117-1119
-
-
Kim, K.1
Zhao, R.2
Doi, A.3
Ng, K.4
Unternaehrer, J.5
Cahan, P.6
Hong-guang, H.7
Loh, Y.H.8
Aryee, M.J.9
Lensch, M.W.10
Li, H.11
Collins, J.J.12
Feinberg, A.P.13
Daley, G.Q.14
-
95
-
-
80052155858
-
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
-
Kim, K. Y., Hysolli, E., and Park, I. H. (2011). Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome. Proc. Natl. Acad. Sci. U.S.A. 108, 14169-14174.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 14169-14174
-
-
Kim, K.Y.1
Hysolli, E.2
Park, I.H.3
-
96
-
-
0033051815
-
Neuroprotective effects of creatine in atransgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi, P., Ferrante, R. J., Matthews, R. T., Bogdanov, M. B., Klein, A. M., Andreassen, O. A., Mueller, G., Wer-mer, M., Kaddurah-Daouk, R., and Beal, M. F. (1999). Neuroprotective effects of creatine in atransgenic animal model of amyotrophic lateral sclerosis. Nat. Med. 5, 347-350.
-
(1999)
Nat. Med.
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wer-mer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
97
-
-
66149179125
-
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine
-
Knoepfler, P. S. (2009). Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells 27, 1050-1056.
-
(2009)
Stem Cells
, vol.27
, pp. 1050-1056
-
-
Knoepfler, P.S.1
-
98
-
-
84355161952
-
Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease
-
Koch, P., Breuer, P., Peitz, M., Jungver-dorben, J., Kesavan, J., Poppe, D., Doerr, J., Ladewig, J., Mertens, J., Tüting, T., Hoffmann, P., Klock-gether, T., Evert, B. O., Wüll-ner, U., and Brüstle, O. (2011). Excitation-induced ataxin-3 aggregation in neurons from patients with Machado-Joseph disease. Nature 480, 543-546.
-
(2011)
Nature
, vol.480
, pp. 543-546
-
-
Koch, P.1
Breuer, P.2
Peitz, M.3
Jungver-dorben, J.4
Kesavan, J.5
Poppe, D.6
Doerr, J.7
Ladewig, J.8
Mertens, J.9
Tüting, T.10
Hoffmann, P.11
Klock-gether, T.12
Evert, B.O.13
Wüll-ner, U.14
Brüstle, O.15
-
99
-
-
79958128131
-
Specification of transplantable astroglial subtypes from human pluripotent stem cells
-
Krencik, R., Weick, J. P., Liu, Y., Zhang, Z. J., and Zhang, S.C. (2011).Specification of transplantable astroglial subtypes from human pluripotent stem cells. Nat. Biotechnol. 29, 528-534.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 528-534
-
-
Krencik, R.1
Weick, J.P.2
Liu, Y.3
Zhang, Z.J.4
Zhang, S.C.5
-
100
-
-
84355166561
-
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease
-
Kriks, S., Shim, J. W., Piao, J., Ganat, Y M., Wakeman, D. R., Xie, Z., Carrillo-Reid, L., Auyeung, G., Antonacci, C., Buch, A., Yang, L., Beal, M. F., Surmeier, D. J., Kordower, J. H., Tabar, V., and Studer, L. (2011). Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease. Nature 480, 547-551.
-
(2011)
Nature
, vol.480
, pp. 547-551
-
-
Kriks, S.1
Shim, J.W.2
Piao, J.3
Ganat, Y.M.4
Wakeman, D.R.5
Xie, Z.6
Carrillo-Reid, L.7
Auyeung, G.8
Antonacci, C.9
Buch, A.10
Yang, L.11
Beal, M.F.12
Surmeier, D.J.13
Kordower, J.H.14
Tabar, V.15
Studer, L.16
-
101
-
-
78049512763
-
Friedreich's ataxia induced pluripotent stem cells model intergenerational GAAATTC triplet repeat instability
-
Ku, S., Soragni, E., Campau, E., Thomas, E. A., Altun, G., Laurent, L. C., Loring, J. F., Napierala, M., and Gottesfeld, J. M. (2010). Friedreich's ataxia induced pluripotent stem cells model intergenerational GAAATTC triplet repeat instability. Cell Stem Cell 7, 631-637.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 631-637
-
-
Ku, S.1
Soragni, E.2
Campau, E.3
Thomas, E.A.4
Altun, G.5
Laurent, L.C.6
Loring, J.F.7
Napierala, M.8
Gottesfeld, J.M.9
-
102
-
-
79960176338
-
Microarray characterization of human embryonic stem cell-derived retinal cultures
-
Lamba, D. A., and Reh, T. A. (2011). Microarray characterization of human embryonic stem cell-derived retinal cultures. Invest. Oph-thalmol. Vis. Sci. 52, 4897-4906.
-
(2011)
Invest. Oph-thalmol. Vis. Sci.
, vol.52
, pp. 4897-4906
-
-
Lamba, D.A.1
Reh, T.A.2
-
103
-
-
77954060569
-
Derivation of neural crest cells from human pluripotent stem cells
-
Lee, G., Chambers, S. M., Tomishima, M. J., and Studer, L. (2010). Derivation of neural crest cells from human pluripotent stem cells. Nat. Protoc. 5, 688-701.
-
(2010)
Nat. Protoc.
, vol.5
, pp. 688-701
-
-
Lee, G.1
Chambers, S.M.2
Tomishima, M.J.3
Studer, L.4
-
104
-
-
36849062137
-
Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells
-
Lee, G., Kim, H., Elkabetz, Y., Al-Shamy, G., Panagiotakos, G., Barberi, T., Tabar,V., and Studer, L. (2007). Isolation and directed differentiation of neural crest stem cells derived from human embryonic stem cells. Nat. Biotechnol. 25, 1468-1475.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1468-1475
-
-
Lee, G.1
Kim, H.2
Elkabetz, Y.3
Al-Shamy, G.4
Panagiotakos, G.5
Barberi, T.6
Tabar, V.7
Studer, L.8
-
105
-
-
34547858511
-
Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons
-
Lee, H., Shamy, G. A., Elkabetz, Y., Schofield, C. M., Harrsion, N. L., Panagiotakos, G., Socci, N. D., Tabar, V., and Studer, L. (2007). Directed differentiation and transplantation of human embryonic stem cell-derived motoneurons. Stem Cells 25, 1931-1939.
-
(2007)
Stem Cells
, vol.25
, pp. 1931-1939
-
-
Lee, H.1
Shamy, G.A.2
Elkabetz, Y.3
Schofield, C.M.4
Harrsion, N.L.5
Panagiotakos, G.6
Socci, N.D.7
Tabar, V.8
Studer, L.9
-
106
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
Lee, G., Papapetrou, E. P., Kim, H., Chambers, S. M., Tomishima, M. J., Fasano, C. A., Ganat, Y. M., Menon, J., Shimizu, F., Viale, A., Tabar, V., Sadelain, M., and Studer, L. (2009). Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 461, 402-406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
Chambers, S.M.4
Tomishima, M.J.5
Fasano, C.A.6
Ganat, Y.M.7
Menon, J.8
Shimizu, F.9
Viale, A.10
Tabar, V.11
Sadelain, M.12
Studer, L.13
-
107
-
-
74049083797
-
Induced pluripotent stem cell technology for the study of human disease
-
Lee, G., and Studer, L. (2010). Induced pluripotent stem cell technology for the study of human disease. Nat. Methods 7, 25-27.
-
(2010)
Nat. Methods
, vol.7
, pp. 25-27
-
-
Lee, G.1
Studer, L.2
-
108
-
-
75649139194
-
Human embryonic stem cells and genomic instability
-
Lefort, N.,Perrier,A. L., Laâbi,Y.,Varela, C., and Peschanski, M. (2009). Human embryonic stem cells and genomic instability. Regen. Med. 4, 899-909.
-
(2009)
Regen. Med.
, vol.4
, pp. 899-909
-
-
Lefort, N.1
Perrier, A.L.2
Laâbi, Y.3
Varela, C.4
Peschanski, M.5
-
109
-
-
77952732489
-
Derivation of pre-X inacti-vation human embryonic stem cells under physiological oxygen concentrations
-
Lengner, C. J., Gimelbrant, A. A., Erwin, J. A., Cheng, A. W., Guenther, M. G., Welstead, G. G., Alagappan, R., Frampton, G. M., Xu, P., Muffat, J., Santagata, S., Powers, D., Barrett, C. B., Young, R. A., Lee, J. T., Jaenisch, R., and Mitalipova, M. (2010). Derivation of pre-X inacti-vation human embryonic stem cells under physiological oxygen concentrations. Cell 141, 872-883.
-
(2010)
Cell
, vol.141
, pp. 872-883
-
-
Lengner, C.J.1
Gimelbrant, A.A.2
Erwin, J.A.3
Cheng, A.W.4
Guenther, M.G.5
Welstead, G.G.6
Alagappan, R.7
Frampton, G.M.8
Xu, P.9
Muffat, J.10
Santagata, S.11
Powers, D.12
Barrett, C.B.13
Young, R.A.14
Lee, J.T.15
Jaenisch, R.16
Mitalipova, M.17
-
110
-
-
79251647135
-
Neuronal chromatin dynamics of imprinting in development and disease
-
Leung, K. N., Chamberlain, S. J., Lalande, M., and Lasalle, J. M. (2011). Neuronal chromatin dynamics of imprinting in development and disease. J. Cell. Biochem. 112, 365-373.
-
(2011)
J. Cell. Biochem.
, vol.112
, pp. 365-373
-
-
Leung, K.N.1
Chamberlain, S.J.2
Lalande, M.3
Lasalle, J.M.4
-
111
-
-
34547700773
-
Proposal of amodel of mammalian neural induction
-
Levine, A. J., and Brivanlou, A. H. (2007). Proposal of amodel of mammalian neural induction. Dev. Biol. 308, 247-256.
-
(2007)
Dev. Biol.
, vol.308
, pp. 247-256
-
-
Levine, A.J.1
Brivanlou, A.H.2
-
112
-
-
83455213526
-
Modeling abnormal early development with induced pluripotent stem cells from aneu-ploid syndromes
-
Li, W., Wang, X., Fan, W., Zhao, P., Chan, Y. C., Chen, S., Zhang, S., Guo, X., Zhang, Y., Li, Y., Cai, J., Qin, D., Li, X., Yang, J., Peng, T., Zychlinski, D., Hoffmann, D., Zhang, R., Deng, K., Ng, K. M., Menten, B., Zhong, M., Wu, J., Li, Z., Chen, Y., Scham-bach, A., Tse, H. F., Pei, D., and Este-ban, M. A. (2012). Modeling abnormal early development with induced pluripotent stem cells from aneu-ploid syndromes. Hum. Mol. Genet. 21, 32-45.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 32-45
-
-
Li, W.1
Wang, X.2
Fan, W.3
Zhao, P.4
Chan, Y.C.5
Chen, S.6
Zhang, S.7
Guo, X.8
Zhang, Y.9
Li, Y.10
Cai, J.11
Qin, D.12
Li, X.13
Yang, J.14
Peng, T.15
Zychlinski, D.16
Hoffmann, D.17
Zhang, R.18
Deng, K.19
Ng, K.M.20
Menten, B.21
Zhong, M.22
Wu, J.23
Li, Z.24
Chen, Y.25
Scham-bach, A.26
Tse, H.F.27
Pei, D.28
Este-ban, M.A.29
more..
-
113
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogram-ming in human induced pluripotent stem cells
-
Lister, R., Pelizzola, M., Kida, Y. S., Hawkins, R. D., Nery, J. R., Hon, G., Antosiewicz-Bourget, J., O'Malley, R., Castanon, R., Klugman, S., Downes, M., Yu, R., Stewart, R., Ren, B., Thomson, J. A., Evans, R. M., and Ecker, J. R. (2011). Hotspots of aberrant epigenomic reprogram-ming in human induced pluripotent stem cells. Nature 471, 68-73.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
Hawkins, R.D.4
Nery, J.R.5
Hon, G.6
Antosiewicz-Bourget, J.7
O'Malley, R.8
Castanon, R.9
Klugman, S.10
Downes, M.11
Yu, R.12
Stewart, R.13
Ren, B.14
Thomson, J.A.15
Evans, R.M.16
Ecker, J.R.17
-
114
-
-
82255175070
-
Specification of neuronal and glial subtypes from human pluripotent stem cells
-
Liu, H., and Zhang, S. C. (2011). Specification of neuronal and glial subtypes from human pluripotent stem cells. Cell. Mol. Life Sci. 68, 3995-4008.
-
(2011)
Cell. Mol. Life Sci.
, vol.68
, pp. 3995-4008
-
-
Liu, H.1
Zhang, S.C.2
-
115
-
-
79960331887
-
Generation of induced pluripotent stem cell lines from Friedreich ataxia patients
-
Liu, J., Verma, P. J., Evans-Galea, M. V., Delatycki, M. B., Michalska, A., Leung, J., Crombie, D., Sarsero, J. P., Williamson, R., Dottori, M., and Pébay A. (2011). Generation of induced pluripotent stem cell lines from Friedreich ataxia patients. Stem Cell Rev. 7, 703-713.
-
(2011)
Stem Cell Rev
, vol.7
, pp. 703-713
-
-
Liu, J.1
Verma, P.J.2
Evans-Galea, M.V.3
Delatycki, M.B.4
Michalska, A.5
Leung, J.6
Crombie, D.7
Sarsero, J.P.8
Williamson, R.9
Dottori, M.10
Pébay, A.11
-
116
-
-
67049164945
-
Generation of induced pluripotent stem cells from human blood
-
Loh, Y H., Agarwal, S., Park, I. H., Urbach, A., Huo, H., Heffner, G. C., Kim, K., Miller, J. D., Ng, K., and Daley, G. Q. (2009). Generation of induced pluripotent stem cells from human blood. Blood 113, 5476-5479.
-
(2009)
Blood
, vol.113
, pp. 5476-5479
-
-
Loh, Y.H.1
Agarwal, S.2
Park, I.H.3
Urbach, A.4
Huo, H.5
Heffner, G.C.6
Kim, K.7
Miller, J.D.8
Ng, K.9
Daley, G.Q.10
-
117
-
-
35948946526
-
Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery
-
Lombardo, A. (2007). Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery. Nat. Biotechnol. 25, 1298-1306.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1298-1306
-
-
Lombardo, A.1
-
118
-
-
70349873363
-
Long-term safety and function of RPE from human embryonic stem cells in pre-clinical models of macular degeneration
-
Lu, B., Malcuit, C., Wang, S., Girman, S., Francis, P., Lemieux, L., Lanza, R., and Lund, R. (2009). Long-term safety and function of RPE from human embryonic stem cells in pre-clinical models of macular degeneration. Stem Cells 27, 2126-2135.
-
(2009)
Stem Cells
, vol.27
, pp. 2126-2135
-
-
Lu, B.1
Malcuit, C.2
Wang, S.3
Girman, S.4
Francis, P.5
Lemieux, L.6
Lanza, R.7
Lund, R.8
-
119
-
-
45249106162
-
Spinal muscular atrophy
-
Lunn, M. R., and Wang, C. H. (2008). Spinal muscular atrophy. Lancet 371, 2120-2133.
-
(2008)
Lancet
, vol.371
, pp. 2120-2133
-
-
Lunn, M.R.1
Wang, C.H.2
-
120
-
-
56549127713
-
Guidelines and techniques for the generation of induced pluripotent stem cells
-
Maherali, N., and Hochedlinger, K. (2008). Guidelines and techniques for the generation of induced pluripotent stem cells. Cell Stem Cell 3, 595-605.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 595-605
-
-
Maherali, N.1
Hochedlinger, K.2
-
121
-
-
27144538978
-
Genomic alterations in cultured human embryonic stem cells
-
Maitra, A., Arking, D. E., Shivapurkar, N., Ikeda, M., Stastny, V., Kassauei, K., Sui, G., Cutler, D. J., Liu, Y., Brimble, S. N., Noaksson, K., Hyll-ner, J., Schulz, T. C., Zeng, X., Freed, W. J., Crook, J., Abraham, S., Colman, A., Sartipy, P., Mat-sui, S. I., Carpenter, M., Gazdar, A. F., Rao, M., and Chakravarti, A. (2005). Genomic alterations in cultured human embryonic stem cells. Nat. Genet. 37, 1099-1103.
-
(2005)
Nat. Genet.
, vol.37
, pp. 1099-1103
-
-
Maitra, A.1
Arking, D.E.2
Shivapurkar, N.3
Ikeda, M.4
Stastny, V.5
Kassauei, K.6
Sui, G.7
Cutler, D.J.8
Liu, Y.9
Brimble, S.N.10
Noaksson, K.11
Hyll-ner, J.12
Schulz, T.C.13
Zeng, X.14
Freed, W.J.15
Crook, J.16
Abraham, S.17
Colman, A.18
Sartipy, P.19
Mat-sui, S.I.20
Carpenter, M.21
Gazdar, A.F.22
Rao, M.23
Chakravarti, A.24
more..
-
122
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto, M. C. N., Carromeu, C., Acab, A., Yu, D., Yeo, G. W., Mu, Y., Chen, G., Gage, F. H., and Muotri, A. R. (2010). A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 143, 527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.N.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
Chen, G.7
Gage, F.H.8
Muotri, A.R.9
-
123
-
-
56549115885
-
Non-cell-autonomous sffect of human SOD1G37R astrocytes on motor neurons derived from human embryonic stem cells
-
Marchetto, M. C. N., Muotri, A. R., Mu, Y., Smith, A. M., Cezar, G. G., and Gage, F. H. (2008). Non-cell-autonomous sffect of human SOD1G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell 3, 649-657.
-
(2008)
Cell Stem Cell
, vol.3
, pp. 649-657
-
-
Marchetto, M.C.N.1
Muotri, A.R.2
Mu, Y.3
Smith, A.M.4
Cezar, G.G.5
Gage, F.H.6
-
124
-
-
59849092634
-
Transgenic mice with defined combinations of drug-inducible reprogramming factors
-
Markoulaki, S., Hanna, J., Beard, C., Carey, B. W., Cheng, A. W., Lengner, C. J., Dausman, J. A., Fu, D., Gao, Q., Wu, S., Cassady, J. P., and Jaenisch, R. (2009). Transgenic mice with defined combinations of drug-inducible reprogramming factors. Nat. Biotechnol. 27, 169-171.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 169-171
-
-
Markoulaki, S.1
Hanna, J.2
Beard, C.3
Carey, B.W.4
Cheng, A.W.5
Lengner, C.J.6
Dausman, J.A.7
Fu, D.8
Gao, Q.9
Wu, S.10
Cassady, J.P.11
Jaenisch, R.12
-
125
-
-
77950688386
-
Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells
-
Maroof, A. M., Brown, K., Shi, S. H., Studer, L., and Anderson, S. A. (2010). Prospective isolation of cortical interneuron precursors from mouse embryonic stem cells. J. Neu-rosci. 30, 4667-4675.
-
(2010)
J. Neu-rosci.
, vol.30
, pp. 4667-4675
-
-
Maroof, A.M.1
Brown, K.2
Shi, S.H.3
Studer, L.4
Anderson, S.A.5
-
126
-
-
84866270039
-
Generation and applications of human pluripotent stem cells induced into neural lineages and neural tissues
-
doi:10.3389/fphys.2012.00047
-
Martinez, Y., Dubois-Dauphin, M., and Krause, K. H. (2012). Generation and applications of human pluripotent stem cells induced into neural lineages and neural tissues. Front. Physiol. 3:47. doi:10.3389/fphys.2012.00047
-
(2012)
Front. Physiol.
, vol.3
, pp. 47
-
-
Martinez, Y.1
Dubois-Dauphin, M.2
Krause, K.H.3
-
127
-
-
31544441632
-
Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders
-
Mateizel, I., De Temmerman, N., Ullmann, U., Cauffman, G., Sermon, K., Van De Velde, H., De Rycke, M., Degreef, E., Devroey, P., Liebaers, I., and Van Steirteghem, A. (2006). Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders. Hum. Reprod. 21, 503-511.
-
(2006)
Hum. Reprod.
, vol.21
, pp. 503-511
-
-
Mateizel, I.1
De Temmerman, N.2
Ullmann, U.3
Cauffman, G.4
Sermon, K.5
Van De Velde, H.6
De Rycke, M.7
Degreef, E.8
Devroey, P.9
Liebaers, I.10
Van Steirteghem, A.11
-
128
-
-
79952710923
-
Induced pluripotent stem cells: a new revolution for clinical neurology?
-
Mattis,V.B.,and Svendsen,C.N. (2011). Induced pluripotent stem cells: a new revolution for clinical neurology? LancetNeurol. 10, 383-394.
-
(2011)
LancetNeurol
, vol.10
, pp. 383-394
-
-
Mattis, V.B.1
Svendsen, C.N.2
-
129
-
-
77957334627
-
Identification and classification of chromosomal aberrations in human induced pluripotent stem cells
-
Mayshar, Y., Ben-David, U., Lavon, N., Biancotti, J. C., Yakir, B., Clark, A. T., Plath, K., Lowry, W E., and Ben-venisty, N. (2010). Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell 7, 521-531.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 521-531
-
-
Mayshar, Y.1
Ben-David, U.2
Lavon, N.3
Biancotti, J.C.4
Yakir, B.5
Clark, A.T.6
Plath, K.7
Lowry, W.E.8
Ben-venisty, N.9
-
130
-
-
79960880834
-
Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment
-
Meyer, J. S., Howden, S. E., Wallace, K. A., Verhoeven, A. D., Wright, L. S., Capowski, E. E., Pinilla, I., Martin, J. M., Tian, S., Stewart, R., Pattnaik, B., Thomson, J. A., and Gamm, D. M. (2011). Optic vesicle-like structures derived from human pluripotent stem cells facilitate a customized approach to retinal disease treatment. Stem Cells 29, 1206-1218.
-
(2011)
Stem Cells
, vol.29
, pp. 1206-1218
-
-
Meyer, J.S.1
Howden, S.E.2
Wallace, K.A.3
Verhoeven, A.D.4
Wright, L.S.5
Capowski, E.E.6
Pinilla, I.7
Martin, J.M.8
Tian, S.9
Stewart, R.10
Pattnaik, B.11
Thomson, J.A.12
Gamm, D.M.13
-
131
-
-
70349750277
-
Modeling early retinal development with human embryonic and induced pluripotent stem cells
-
Meyer, J. S., Shearer, R. L., Capowski, E. E., Wright, L. S., Wallace, K. A., Mcmillan, E. L., Zhang, S. C., and Gamm, D. M. (2009). Modeling early retinal development with human embryonic and induced pluripotent stem cells. Proc. Natl. Acad. Sci. U.S.A. 106, 16698-16703.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 16698-16703
-
-
Meyer, J.S.1
Shearer, R.L.2
Capowski, E.E.3
Wright, L.S.4
Wallace, K.A.5
Mcmillan, E.L.6
Zhang, S.C.7
Gamm, D.M.8
-
132
-
-
46449094276
-
Dissecting direct reprogramming through integrative genomic analysis
-
Mikkelsen, T. S., Hanna, J., Zhang, X., Ku, M., Wernig, M., Schorderet, P., Bernstein, B. E., Jaenisch, R., Lander, E. S., and Meissner, A. (2008). Dissecting direct reprogramming through integrative genomic analysis. Nature 454, 49-55.
-
(2008)
Nature
, vol.454
, pp. 49-55
-
-
Mikkelsen, T.S.1
Hanna, J.2
Zhang, X.3
Ku, M.4
Wernig, M.5
Schorderet, P.6
Bernstein, B.E.7
Jaenisch, R.8
Lander, E.S.9
Meissner, A.10
-
133
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller, J. C. (2007). An improved zinc-finger nuclease architecture for highly specific genome editing. Nat. Biotechnol. 25, 778-785.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
-
134
-
-
17044364465
-
Preserving the genetic integrity of human embryonic stem cells
-
Mitalipova, M. M., Rao, R. R., Hoyer, D. M., Johnson, J. A., Meisner, L. F., Jones, K. L., Dalton, S., and Stice, S. L. (2005). Preserving the genetic integrity of human embryonic stem cells. Nat. Biotechnol. 23, 19-20.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 19-20
-
-
Mitalipova, M.M.1
Rao, R.R.2
Hoyer, D.M.3
Johnson, J.A.4
Meisner, L.F.5
Jones, K.L.6
Dalton, S.7
Stice, S.L.8
-
135
-
-
80052225992
-
Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients
-
Mitne-Neto, M., Machado-Costa, M., Marchetto, M. C. N., Bengtson, M. H., Joazeiro, C. A., Tsuda, H., Bellen, H. J., Silva, H. C. A., Oliveira, A. S. B., Lazar, M., Muotri, A. R.,and Zatz, M. (2011). Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum. Mol. Genet. 20, 3642-3652.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 3642-3652
-
-
Mitne-Neto, M.1
Machado-Costa, M.2
Marchetto, M.C.N.3
Bengtson, M.H.4
Joazeiro, C.A.5
Tsuda, H.6
Bellen, H.J.7
Silva, H.C.A.8
Oliveira, A.S.B.9
Lazar, M.10
Muotri, A.R.11
and Zatz, M.12
-
136
-
-
33847682924
-
Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases
-
Moehle, E. A. (2007). Targeted gene addition into a specified location in the human genome using designed zinc finger nucleases. Proc. Natl. Acad. Sci. U.S.A. 104, 3055-3060.
-
(2007)
Proc. Natl. Acad. Sci. U. S. A.
, vol.104
, pp. 3055-3060
-
-
Moehle, E.A.1
-
137
-
-
0036546980
-
Neural induction, the default model and embryonic stem cells
-
Munoz-Sanjuan, I., and Brivanlou, A. H. (2002). Neural induction, the default model and embryonic stem cells. Nat. Rev. Neurosci. 3, 271-280.
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 271-280
-
-
Munoz-Sanjuan, I.1
Brivanlou, A.H.2
-
138
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by MeCP2
-
Muotri, A. R., Marchetto, M. C. N., Coufal, N. G., Oefner, R., Yeo, G., Nakashima, K., and Gage, F. H. (2010). L1 retrotransposition in neurons is modulated by MeCP2. Nature 468, 443-446.
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
Marchetto, M.C.N.2
Coufal, N.G.3
Oefner, R.4
Yeo, G.5
Nakashima, K.6
Gage, F.H.7
-
139
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development
-
Murry, C. E., and Keller, G. (2008). Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132, 661-680.
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
140
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa, M., Koyanagi, M., Tanabe, K., Takahashi, K., Ichisaka, T., Aoi, T., Okita, K., Mochiduki, Y., Takizawa, N., and Yamanaka, S. (2008). Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26, 101-106.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
Koyanagi, M.2
Tanabe, K.3
Takahashi, K.4
Ichisaka, T.5
Aoi, T.6
Okita, K.7
Mochiduki, Y.8
Takizawa, N.9
Yamanaka, S.10
-
141
-
-
78650903501
-
Rett syndrome: revised diagnostic criteria and nomenclature
-
Neul, J. L., Kaufmann, W. E., Glaze, D. G., Christodoulou, J., Clarke, A. J., Bahi-Buisson, N., Leonard, H., Bailey, M. E. S., Schanen, N. C., Zap-pella, M., Renieri, A., Huppke, P., and Percy, A. K. (2010). Rett syndrome: revised diagnostic criteria and nomenclature. Ann. Neurol. 68, 944-950.
-
(2010)
Ann. Neurol.
, vol.68
, pp. 944-950
-
-
Neul, J.L.1
Kaufmann, W.E.2
Glaze, D.G.3
Christodoulou, J.4
Clarke, A.J.5
Bahi-Buisson, N.6
Leonard, H.7
Bailey, M.E.S.8
Schanen, N.C.9
Zap-pella, M.10
Renieri, A.11
Huppke, P.12
Percy, A.K.13
-
142
-
-
79952172335
-
LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
-
Nguyen, H. N., Byers, B., Cord, B., Shcheglovitov, A., Byrne, J., Gujar, P., Kee, K., Schüle, B., Dolmetsch, R. E., Langston, W., Palmer, T. D., and Pera, R. R. (2011). LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. Cell Stem Cell 8, 267-280.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 267-280
-
-
Nguyen, H.N.1
Byers, B.2
Cord, B.3
Shcheglovitov, A.4
Byrne, J.5
Gujar, P.6
Kee, K.7
Schüle, B.8
Dolmetsch, R.E.9
Langston, W.10
Palmer, T.D.11
Pera, R.R.12
-
143
-
-
68149162402
-
Human embryonic stem cell models of Huntington disease
-
Niclis, J. C., Trounson, A. O., Dottori, M., Ellisdon, A. M., Bottomley, S. P., Verlinsky, Y., and Cram, D. S. (2009). Human embryonic stem cell models of Huntington disease. Reprod. Biomed. Online 19, 106-113.
-
(2009)
Reprod. Biomed. Online
, vol.19
, pp. 106-113
-
-
Niclis, J.C.1
Trounson, A.O.2
Dottori, M.3
Ellisdon, A.M.4
Bottomley, S.P.5
Verlinsky, Y.6
Cram, D.S.7
-
144
-
-
80053628732
-
Grafted human-induced pluripotent stem-cell-derived neu-rospheres promote motor functional recovery after spinal cord injury in mice
-
Nori, S., Okada, Y., Yasuda, A., Tsuji, O., Takahashi, Y., Kobayashi, Y., Fujiyoshi, K., Koike, M., Uchiyama, Y., Ikeda, E., Toyama, Y., Yamanaka, S., Nakamura, M., and Okano, H. (2011). Grafted human-induced pluripotent stem-cell-derived neu-rospheres promote motor functional recovery after spinal cord injury in mice. Proc. Natl. Acad. Sci. U.S.A. 108, 16825-16830.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 16825-16830
-
-
Nori, S.1
Okada, Y.2
Yasuda, A.3
Tsuji, O.4
Takahashi, Y.5
Kobayashi, Y.6
Fujiyoshi, K.7
Koike, M.8
Uchiyama, Y.9
Ikeda, E.10
Toyama, Y.11
Yamanaka, S.12
Nakamura, M.13
Okano, H.14
-
145
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita, K., Ichisaka, T., and Yamanaka, S. (2007). Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317.
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
146
-
-
73149094719
-
Modelingtheevolution of culture-adapted human embryonic stem cells
-
Olariu, V., Harrison, N. J., Coca, D., Gokhale, P. J., Baker, D., Billings, S., Kadirkamanathan, V., and Andrews, P.W. (2010).Modelingtheevolution of culture-adapted human embryonic stem cells. Stem Cell Res. 4, 50-56.
-
(2010)
Stem Cell Res
, vol.4
, pp. 50-56
-
-
Olariu, V.1
Harrison, N.J.2
Coca, D.3
Gokhale, P.J.4
Baker, D.5
Billings, S.6
Kadirkamanathan, V.7
Andrews, P.W.8
-
147
-
-
70349347145
-
In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction
-
Osakada, F., Jin, Z. B., Hirami, Y., Ikeda, H., Danjyo, T., Watanabe, K., Sasai, Y., and Takahashi, M. (2009). In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. J. Cell Sci. 122, 3169-3179.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3169-3179
-
-
Osakada, F.1
Jin, Z.B.2
Hirami, Y.3
Ikeda, H.4
Danjyo, T.5
Watanabe, K.6
Sasai, Y.7
Takahashi, M.8
-
148
-
-
69149110152
-
Sto-ichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
-
Papapetrou, E. P., Tomishima, M. J., Chambers, S. M., Mica, Y., Reed, E., Menon, J., Tabar, V., Mo, Q., Studer, L., and Sadelain, M. (2009). Sto-ichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc. Natl. Acad. Sci. U.S.A. 106, 12759-12764.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 12759-12764
-
-
Papapetrou, E.P.1
Tomishima, M.J.2
Chambers, S.M.3
Mica, Y.4
Reed, E.5
Menon, J.6
Tabar, V.7
Mo, Q.8
Studer, L.9
Sadelain, M.10
-
149
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park, I. H., Arora, N., Huo, H., Maher-ali, N., Ahfeldt, T., Shimamura, A., Lensch, M. W., Cowan, C., Hochedlinger, K., and Daley, G. Q. (2008). Disease-specific induced pluripotent stem cells. Cell 134, 877-886.
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maher-ali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
150
-
-
34147131206
-
Dominantly inherited ataxias: lessons learned from Machado-Joseph dis-ease/spinocerebellar ataxia type 3
-
Paulson, H. L. (2007). Dominantly inherited ataxias: lessons learned from Machado-Joseph dis-ease/spinocerebellar ataxia type 3. Semin. Neurol. 27, 133-142.
-
(2007)
Semin. Neurol.
, vol.27
, pp. 133-142
-
-
Paulson, H.L.1
-
151
-
-
1842426937
-
Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin
-
Pera, M. F., Andrade, J., Houssami, S., Reubinoff, B., Trounson, A., Stanley, E. G., Oostwaard, D. W. V., and Mummery, C. (2004). Regulation of human embryonic stem cell differentiation by BMP-2 and its antagonist noggin. J. Cell Sci. 117, 1269-1280.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 1269-1280
-
-
Pera, M.F.1
Andrade, J.2
Houssami, S.3
Reubinoff, B.4
Trounson, A.5
Stanley, E.G.6
Oostwaard, D.W.V.7
Mummery, C.8
-
152
-
-
81855194037
-
Stem cell sources for regenerative medicine: the immunological point of view
-
Preynat-Seauve, O., and Krause, K. H. (2011). Stem cell sources for regenerative medicine: the immunological point of view. Semin. Immunopathol. 33, 519-524.
-
(2011)
Semin. Immunopathol.
, vol.33
, pp. 519-524
-
-
Preynat-Seauve, O.1
Krause, K.H.2
-
154
-
-
77957598016
-
iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability
-
Ramos-Mejia, V., Munoz-Lopez, M., Garcia-Perez, J. L., and Menendez, P. (2010). iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability. Cell Res. 20, 1092-1095.
-
(2010)
Cell Res
, vol.20
, pp. 1092-1095
-
-
Ramos-Mejia, V.1
Munoz-Lopez, M.2
Garcia-Perez, J.L.3
Menendez, P.4
-
155
-
-
0035203881
-
Neural progenitors from human embryonic stem cells
-
Reubinoff, B. E., Itsykson, P., Turetsky, T., Pera, M. F., Reinhartz, E., Itzik, A., and Ben-Hur, T. (2001). Neural progenitors from human embryonic stem cells. Nat. Biotechnol. 19, 1134-1140.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 1134-1140
-
-
Reubinoff, B.E.1
Itsykson, P.2
Turetsky, T.3
Pera, M.F.4
Reinhartz, E.5
Itzik, A.6
Ben-Hur, T.7
-
156
-
-
79957913513
-
Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease
-
Rhee, Y H., Ko, J. Y., Chang, M. Y., Yi, S. H., Kim, D., Kim, C. H., Shim, J. W., Jo, A. Y., Kim, B. W., Lee, H., Lee, S. H., Suh, W., Park, C. H., Koh, H. C., Lee, Y. S., Lanza, R., Kim, K. S., and Lee, S. H. (2011). Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease. J. Clin. Invest. 121, 2326-2335.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 2326-2335
-
-
Rhee, Y.H.1
Ko, J.Y.2
Chang, M.Y.3
Yi, S.H.4
Kim, D.5
Kim, C.H.6
Shim, J.W.7
Jo, A.Y.8
Kim, B.W.9
Lee, H.10
Lee, S.H.11
Suh, W.12
Park, C.H.13
Koh, H.C.14
Lee, Y.S.15
Lanza, R.16
Kim, K.S.17
Lee, S.H.18
-
157
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismu-tase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., Donaldson, D., Goto, J., O'Regan, J. P., Deng, H. X., Rahmani, Z., Krizus, A., Mckenna-Yasek, D., Cayabyab, A., Gaston, S. M., Berger, R., Tanzi, R. E., Halperin, J. J., Herzfeldt, B., Van Den Bergh, R., Hung, W. Y., Bird, T., Deng, G., Mulder, D. W., Smyth, C., Laing, N. G., Soriano, E., Pericak-Vance, M. A., Haines, J., Rouleau, G. A., Gusella, J. S., Horvitz, H. R., and Brown, R. H. (1993). Mutations in Cu/Zn superoxide dismu-tase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
Rahmani, Z.11
Krizus, A.12
Mckenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.M.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
Van Den Bergh, R.20
Hung, W.Y.21
Bird, T.22
Deng, G.23
Mulder, D.W.24
Smyth, C.25
Laing, N.G.26
Soriano, E.27
Pericak-Vance, M.A.28
Haines, J.29
Rouleau, G.A.30
Gusella, J.S.31
Horvitz, H.R.32
Brown, R.H.33
more..
-
158
-
-
33750706917
-
Functional engraftment of human ES cell-derived dopamin-ergic neurons enriched by cocul-ture with telomerase-immortalized midbrain astrocytes
-
Roy, N. S., Cleren, C., Singh, S. K., Yang, L., Beal, M. F., and Goldman, S. A. (2006). Functional engraftment of human ES cell-derived dopamin-ergic neurons enriched by cocul-ture with telomerase-immortalized midbrain astrocytes. Nat. Med. 12, 1259-1268.
-
(2006)
Nat. Med.
, vol.12
, pp. 1259-1268
-
-
Roy, N.S.1
Cleren, C.2
Singh, S.K.3
Yang, L.4
Beal, M.F.5
Goldman, S.A.6
-
159
-
-
71549120380
-
The role of Myc-induced protein synthesis in cancer
-
Ruggero, D. (2009). The role of Myc-induced protein synthesis in cancer. Cancer Res. 69, 8839-8843.
-
(2009)
Cancer Res
, vol.69
, pp. 8839-8843
-
-
Ruggero, D.1
-
160
-
-
49649095887
-
Neuroscience: standard model
-
Schnabel, J. (2008). Neuroscience: standard model. Nature 454, 682-685.
-
(2008)
Nature
, vol.454
, pp. 682-685
-
-
Schnabel, J.1
-
161
-
-
34247139885
-
Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation
-
Schneider, B. L., Seehus, C. R., Capowski, E. E.,Aebischer, P.,Zhang, S. C., and Svendsen, C. N. (2007). Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation. Hum. Mol. Genet. 16, 651-666.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 651-666
-
-
Schneider, B.L.1
Seehus, C.R.2
Capowski, E.E.3
Aebischer, P.4
Zhang, S.C.5
Svendsen, C.N.6
-
162
-
-
67649213875
-
Diagnosis and treatment of Friedreich ataxia: a European perspective
-
Schulz, J. B., Boesch, S., Burk, K., Durr, A., Giunti, P., Mariotti, C., Pousset, F., Schols, L., Vankan, P., and Pandolfo, M. (2009). Diagnosis and treatment of Friedreich ataxia: a European perspective. Nat. Rev. Neurol. 5, 222-234.
-
(2009)
Nat. Rev. Neurol.
, vol.5
, pp. 222-234
-
-
Schulz, J.B.1
Boesch, S.2
Burk, K.3
Durr, A.4
Giunti, P.5
Mariotti, C.6
Pousset, F.7
Schols, L.8
Vankan, P.9
Pandolfo, M.10
-
163
-
-
84857643783
-
Embryonic stem cell trials for macular degeneration: a prelim inary report
-
Schwartz, S. D., Hubschman, J. P., Heil-well, G., Franco-Cardenas, V., Pan, C. K., Ostrick, R. M., Mickunas, E., Gay, R., Klimanskaya, I., and Lanza, R. (2012). Embryonic stem cell trials for macular degeneration: a prelim inary report. Lancet 379, 713-720.
-
(2012)
Lancet
, vol.379
, pp. 713-720
-
-
Schwartz, S.D.1
Hubschman, J.P.2
Heil-well, G.3
Franco-Cardenas, V.4
Pan, C.K.5
Ostrick, R.M.6
Mickunas, E.7
Gay, R.8
Klimanskaya, I.9
Lanza, R.10
-
164
-
-
39349107014
-
Design, power, and interpretation of studies in the standard murine model of ALS
-
Scott, S., Kranz, J. E., Cole, J., Lince-cum, J. M., Thompson, K., Kelly, N., Bostrom, A., Theodoss, J., Al-Nakhala, B. M., Vieira, E G., Rama-subbu, J.,andHeywood, J.A. (2008). Design, power, and interpretation of studies in the standard murine model of ALS. Amyotroph. Lateral Scler. 9, 4-15.
-
(2008)
Amyotroph. Lateral Scler.
, vol.9
, pp. 4-15
-
-
Scott, S.1
Kranz, J.E.2
Cole, J.3
Lince-cum, J.M.4
Thompson, K.5
Kelly, N.6
Bostrom, A.7
Theodoss, J.8
Al-Nakhala, B.M.9
Vieira, E.G.10
Rama-subbu, J.11
Heywood, J.A.12
-
165
-
-
80054918967
-
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases
-
Sebastiano, V., Maeder, M. L., Angst-man, J. F., Haddad, B., Khayter, C., Yeo, D. T., Goodwin, M. J., Hawkins, J. S., Ramirez, C. L., Batista, L. E Z., Artandi, S. E., Wernig, M., and Joung, J. K. (2011). In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells 29, 1717-1726.
-
(2011)
Stem Cells
, vol.29
, pp. 1717-1726
-
-
Sebastiano, V.1
Maeder, M.L.2
Angst-man, J.F.3
Haddad, B.4
Khayter, C.5
Yeo, D.T.6
Goodwin, M.J.7
Hawkins, J.S.8
Ramirez, C.L.9
Batista, L.E.Z.10
Artandi, S.E.11
Wernig, M.12
Joung, J.K.13
-
166
-
-
79955786943
-
Mitochondrial Parkin recruitment is impaired in neu rons derived from mutant PINK1 induced pluripotent stem cells
-
Seibler, P., Graziotto, J., Jeong, H., Simunovic, F., Klein, C., and Krainc, D. (2011). Mitochondrial Parkin recruitment is impaired in neu rons derived from mutant PINK1 induced pluripotent stem cells. J. Neurosci. 31, 5970-5976.
-
(2011)
J. Neurosci
, vol.31
, pp. 5970-5976
-
-
Seibler, P.1
Graziotto, J.2
Jeong, H.3
Simunovic, F.4
Klein, C.5
Krainc, D.6
-
167
-
-
79956016292
-
Huntington's and myotonic dystrophy hESCs: down-regulated trinu-cleotide repeat instability and mismatch repair machinery expression upon differentiation
-
Seriola, A., Spits, C., Simard, J. P., Hilven, P., Haentjens, P., Pearson, C. E., and Sermon, K. (2011). Huntington's and myotonic dystrophy hESCs: down-regulated trinu-cleotide repeat instability and mismatch repair machinery expression upon differentiation. Hum. Mol. Genet. 20, 176-185.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 176-185
-
-
Seriola, A.1
Spits, C.2
Simard, J.P.3
Hilven, P.4
Haentjens, P.5
Pearson, C.E.6
Sermon, K.7
-
168
-
-
79953797190
-
Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells
-
Sharon, N., Mor, I., Golan-Lev, T., Fainsod, A., and Benvenisty, N. (2011). Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells. Stem Cells 29, 600-608.
-
(2011)
Stem Cells
, vol.29
, pp. 600-608
-
-
Sharon, N.1
Mor, I.2
Golan-Lev, T.3
Fainsod, A.4
Benvenisty, N.5
-
169
-
-
8644289377
-
Neals Consortium A clinical trial of creatine in ALS
-
Shefner, J. M., Cudkowicz, M. E., Schoenfeld, D., Conrad, T., Taft, J., Chilton, M., Urbinelli, L., Qureshi, M., Zhang, H., Pestronk, A., Caress, J., Donofrio, P., Sorenson, E., Bradley, W., Lomen-Hoerth, C., Pioro, E., Rezania, K., Ross, M., Pas-cuzzi, R., Heiman-Patterson, T., Tan-dan, R., Mitsumoto, H., Rothstein, J., Smith-Palmer, T., Macdonald, D., Burke, D., and Neals Consortium. (2004). A clinical trial of creatine in ALS. Neurology 63, 1656-1661.
-
(2004)
Neurology
, vol.63
, pp. 1656-1661
-
-
Shefner, J.M.1
Cudkowicz, M.E.2
Schoenfeld, D.3
Conrad, T.4
Taft, J.5
Chilton, M.6
Urbinelli, L.7
Qureshi, M.8
Zhang, H.9
Pestronk, A.10
Caress, J.11
Donofrio, P.12
Sorenson, E.13
Bradley, W.14
Lomen-Hoerth, C.15
Pioro, E.16
Rezania, K.17
Ross, M.18
Pas-cuzzi, R.19
Heiman-Patterson, T.20
Tan-dan, R.21
Mitsumoto, H.22
Rothstein, J.23
Smith-Palmer, T.24
Macdonald, D.25
Burke, D.26
more..
-
170
-
-
80053948646
-
Epige-netic characterization of the FMR1 gene and aberrant neurodevelop-ment in human induced pluripotent stem cell models of fragile X syndrome
-
doi:10.1371/journal.pone.0026203
-
Sheridan, S. D., Theriault, K. M., Reis, S. A., Zhou, F., Madison, J. M., Daheron, L., Loring, J. F., and Haggarty S. J. (2011). Epige-netic characterization of the FMR1 gene and aberrant neurodevelop-ment in human induced pluripotent stem cell models of fragile X syndrome. PLoS ONE 6, e26203. doi:10.1371/journal.pone.0026203
-
(2011)
PLoS ONE
, vol.6
-
-
Sheridan, S.D.1
Theriault, K.M.2
Reis, S.A.3
Zhou, F.4
Madison, J.M.5
Daheron, L.6
Loring, J.F.7
Haggarty, S.J.8
-
171
-
-
44349103591
-
A combined chemical and genetic approach for the generation of induced pluripotent stem cells
-
Shi, Y., Do, J. T., Desponts, C., Hahm, H. S., Schöler, H. R., and Ding, S. (2008). A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell 2, 525-528.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 525-528
-
-
Shi, Y.1
Do, J.T.2
Desponts, C.3
Hahm, H.S.4
Schöler, H.R.5
Ding, S.6
-
172
-
-
37349052866
-
Inhibition of activin/nodal signaling promotes specification of human embryonic stem cells into neuroectoderm
-
Smith, J. R., Vallier, L., Lupo, G., Alexander, M., Harris, W. A., and Pedersen, R. A. (2008). Inhibition of activin/nodal signaling promotes specification of human embryonic stem cells into neuroectoderm. Dev. Biol. 313, 107-117.
-
(2008)
Dev. Biol.
, vol.313
, pp. 107-117
-
-
Smith, J.R.1
Vallier, L.2
Lupo, G.3
Alexander, M.4
Harris, W.A.5
Pedersen, R.A.6
-
173
-
-
61349100729
-
Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
-
Soldner, F., Hockemeyer, D., Beard, C., Gao, Q., Bell, G. W., Cook, E. G., Hargus, G., Blak, A., Cooper, O., Mitalipova, M., Isacson, O., and Jaenisch, R. (2009). Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136, 964-977.
-
(2009)
Cell
, vol.136
, pp. 964-977
-
-
Soldner, F.1
Hockemeyer, D.2
Beard, C.3
Gao, Q.4
Bell, G.W.5
Cook, E.G.6
Hargus, G.7
Blak, A.8
Cooper, O.9
Mitalipova, M.10
Isacson, O.11
Jaenisch, R.12
-
174
-
-
75349095926
-
Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector
-
Sommer, C. A., Sommer, A. G., Long-mire, T. A., Christodoulou, C., Thomas, D. D., Gostissa, M., Alt, E W., Murphy, G. J., Kotton, D. N., and Mostoslavsky, G. (2010). Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells 28, 64-74.
-
(2010)
Stem Cells
, vol.28
, pp. 64-74
-
-
Sommer, C.A.1
Sommer, A.G.2
Long-mire, T.A.3
Christodoulou, C.4
Thomas, D.D.5
Gostissa, M.6
Alt, E.W.7
Murphy, G.J.8
Kotton, D.N.9
Mostoslavsky, G.10
-
175
-
-
57449090630
-
Recurrent chromosomal abnormalities in human embryonic stem cells
-
Spits, C., Mateizel, I., Geens, M., Mertzanidou, A., Staessen, C., Van-deskelde, Y., Van Der Elst, J., Liebaers, I., and Sermon, K. (2008). Recurrent chromosomal abnormalities in human embryonic stem cells. Nat. Biotechnol. 26, 1361-1363.
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 1361-1363
-
-
Spits, C.1
Mateizel, I.2
Geens, M.3
Mertzanidou, A.4
Staessen, C.5
Van-deskelde, Y.6
Van Der Elst, J.7
Liebaers, I.8
Sermon, K.9
-
176
-
-
45449094570
-
Repro-gramming of pancreatic beta cells into induced pluripotent stem cells
-
Stadtfeld, M., Brennand, K., and Hochedlinger, K. (2008). Repro-gramming of pancreatic beta cells into induced pluripotent stem cells. Curr. Biol. 18, 890-894.
-
(2008)
Curr. Biol.
, vol.18
, pp. 890-894
-
-
Stadtfeld, M.1
Brennand, K.2
Hochedlinger, K.3
-
177
-
-
57449109722
-
Preimplanta-tion genetic diagnosis as a source of human embryonic stem cells for disease research and drug discovery
-
Stephenson, E. L., Mason, C., and Braude, P. R. (2009). Preimplanta-tion genetic diagnosis as a source of human embryonic stem cells for disease research and drug discovery. BJOG 116, 158-165.
-
(2009)
BJOG
, vol.116
, pp. 158-165
-
-
Stephenson, E.L.1
Mason, C.2
Braude, P.R.3
-
178
-
-
19744364989
-
Neural induction: old problem, new findings, yet more questions
-
Stern, C. D. (2005). Neural induction: old problem, new findings, yet more questions. Development 132, 2007-2021.
-
(2005)
Development
, vol.132
, pp. 2007-2021
-
-
Stern, C.D.1
-
179
-
-
33750632535
-
Neural induction: 10 years on since the 'default model'
-
Stern, C. D. (2006). Neural induction: 10 years on since the 'default model.' Curr. Opin. Cell Biol. 18, 692-697.
-
(2006)
Curr. Opin. Cell Biol.
, vol.18
, pp. 692-697
-
-
Stern, C.D.1
-
180
-
-
49449102627
-
Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy
-
Suter, D. M., and Krause, K. H. (2008). Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy. J. Pathol. 215, 355-368.
-
(2008)
J. Pathol.
, vol.215
, pp. 355-368
-
-
Suter, D.M.1
Krause, K.H.2
-
181
-
-
0032409396
-
A new method for the rapid and long term growth of human neural precursor cells
-
Svendsen, C. N., Ter Borg, M. G., Armstrong, R. J., Rosser, A. E., Chandran, S., Ostenfeld, T., and Caldwell, M. A. (1998). A new method for the rapid and long term growth of human neural precursor cells. J. Neurosci. Methods 85, 141-152.
-
(1998)
J. Neurosci. Methods
, vol.85
, pp. 141-152
-
-
Svendsen, C.N.1
Ter Borg, M.G.2
Armstrong, R.J.3
Rosser, A.E.4
Chandran, S.5
Ostenfeld, T.6
Caldwell, M.A.7
-
182
-
-
79953854769
-
Karyotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells
-
Taapken, S. M., Nisler, B. S., Newton, M. A., Sampsell-Barron, T. L., Leonhard, K. A., Mcintire, E. M., and Montgomery, K. D. (2011). Karyotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells. Nat. Biotechnol. 29, 313-314.
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 313-314
-
-
Taapken, S.M.1
Nisler, B.S.2
Newton, M.A.3
Sampsell-Barron, T.L.4
Leonhard, K.A.5
Mcintire, E.M.6
Montgomery, K.D.7
-
183
-
-
22444449591
-
Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
-
Tabar, V., Panagiotakos, G., Green-berg, E. D., Chan, B. K., Sadelain, M., Gutin, P. H., and Studer, L. (2005). Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nat. Biotechnol. 23, 601-606.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 601-606
-
-
Tabar, V.1
Panagiotakos, G.2
Green-berg, E.D.3
Chan, B.K.4
Sadelain, M.5
Gutin, P.H.6
Studer, L.7
-
184
-
-
41849093685
-
Therapeutic cloning in individual parkinsonian mice
-
Tabar, V., Tomishima, M., Panagiotakos, G., Wakayama, S., Menon, J., Chan, B., Mizutani, E., Al-Shamy, G., Ohta, H., Wakayama, T., and Studer, L. (2008). Therapeutic cloning in individual parkinsonian mice. Nat. Med. 14, 379-381.
-
(2008)
Nat. Med.
, vol.14
, pp. 379-381
-
-
Tabar, V.1
Tomishima, M.2
Panagiotakos, G.3
Wakayama, S.4
Menon, J.5
Chan, B.6
Mizutani, E.7
Al-Shamy, G.8
Ohta, H.9
Wakayama, T.10
Studer, L.11
-
185
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibrob-lasts by defined factors
-
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibrob-lasts by defined factors. Cell 131, 861-872.
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
186
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K., and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
187
-
-
0032491416
-
Embryonic stem cell lines derived from human blas-tocysts
-
Thomson, J. A., Itskovitz-Eldor, J., Shapiro, S. S., Waknitz, M. A., Swiergiel, J. J., Marshall, V. S., and Jones, J. M. (1998). Embryonic stem cell lines derived from human blas-tocysts. Science 282, 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
188
-
-
79956124889
-
Optimal reprogram-ming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells
-
Tiemann, U., Sgodda, M., Warlich, E., Ballmaier, M., Schöler, H. R., Schambach, A., and Cantz, T. (2011). Optimal reprogram-ming factor stoichiometry increases colony numbers and affects molecular characteristics of murine induced pluripotent stem cells. Cytometry A 79A, 426-435.
-
(2011)
Cytometry A
, vol.79 A
, pp. 426-435
-
-
Tiemann, U.1
Sgodda, M.2
Warlich, E.3
Ballmaier, M.4
Schöler, H.R.5
Schambach, A.6
Cantz, T.7
-
189
-
-
77952098043
-
High-efficiency derivation of human embryonic stem cell lines following pre-implantation genetic diagnosis
-
Tropel, P., Tournois, J., Côme, J., Varela, C., Moutou, C., Fragner, P., Cailleret, M., Laâbi, Y., Peschanski, M., and Viville, S. (2010). High-efficiency derivation of human embryonic stem cell lines following pre-implantation genetic diagnosis. In vitro Cell. Dev. Biol. Anim. 46, 376-385.
-
(2010)
In vitro Cell. Dev. Biol. Anim.
, vol.46
, pp. 376-385
-
-
Tropel, P.1
Tournois, J.2
Côme, J.3
Varela, C.4
Moutou, C.5
Fragner, P.6
Cailleret, M.7
Laâbi, Y.8
Peschanski, M.9
Viville, S.10
-
190
-
-
0035025619
-
Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism
-
Tropepe, V., Hitoshi, S., Sirard, C., Mak, T. W., Rossant, J., and Van Der Kooy, D. (2001). Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 30, 65-78.
-
(2001)
Neuron
, vol.30
, pp. 65-78
-
-
Tropepe, V.1
Hitoshi, S.2
Sirard, C.3
Mak, T.W.4
Rossant, J.5
Van Der Kooy, D.6
-
191
-
-
80052143586
-
Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pig-mentosa
-
Tucker, B. A., Scheetz, T. E., Mullins, R. F., Deluca, A. P., Hoffmann, J. M., Johnston, R. M., Jacobson, S. G., Sheffield, V. C., and Stone, E. M. (2011). Exome sequencing and analysis of induced pluripotent stem cells identify the cilia-related gene male germ cell-associated kinase (MAK) as a cause of retinitis pig-mentosa. Proc. Natl. Acad. Sci. U.S.A. 108, E569-E576.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
-
-
Tucker, B.A.1
Scheetz, T.E.2
Mullins, R.F.3
Deluca, A.P.4
Hoffmann, J.M.5
Johnston, R.M.6
Jacobson, S.G.7
Sheffield, V.C.8
Stone, E.M.9
-
192
-
-
77956214743
-
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
-
Urbach, A., Bar-Nur, O., Daley, G. Q., and Benvenisty, N. (2010). Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 6, 407-411.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 407-411
-
-
Urbach, A.1
Bar-Nur, O.2
Daley, G.Q.3
Benvenisty, N.4
-
193
-
-
3543030995
-
Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells
-
Urbach, A., Schuldiner, M., and Benvenisty, N. (2004). Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. Stem Cells 22, 635-641.
-
(2004)
Stem Cells
, vol.22
, pp. 635-641
-
-
Urbach, A.1
Schuldiner, M.2
Benvenisty, N.3
-
195
-
-
11944264980
-
Human embryonic stem cell lines with genetic disorders
-
Verlinsky, Y., Strelchenko, N., Kukharenko, V., Rechitsky, S., Verlinsky, O., Galat, V., and Kuliev, A. (2005). Human embryonic stem cell lines with genetic disorders. Reprod. Biomed. Online 10, 105-110.
-
(2005)
Reprod. Biomed. Online
, vol.10
, pp. 105-110
-
-
Verlinsky, Y.1
Strelchenko, N.2
Kukharenko, V.3
Rechitsky, S.4
Verlinsky, O.5
Galat, V.6
Kuliev, A.7
-
196
-
-
0032994516
-
Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation
-
Vescovi, A. L., Parati, E. A., Gritti, A., Poulin, P., Ferrario, M., Wanke, E., Frölichsthal-Schoeller, P., Cova, L., Arcellana-Panlilio, M., Colombo, A., and Galli, R. (1999). Isolation and cloning of multipotential stem cells from the embryonic human CNS and establishment of transplantable human neural stem cell lines by epigenetic stimulation. Exp. Neurol. 156, 71-83.
-
(1999)
Exp. Neurol.
, vol.156
, pp. 71-83
-
-
Vescovi, A.L.1
Parati, E.A.2
Gritti, A.3
Poulin, P.4
Ferrario, M.5
Wanke, E.6
Frölichsthal-Schoeller, P.7
Cova, L.8
Arcellana-Panlilio, M.9
Colombo, A.10
Galli, R.11
-
197
-
-
77952368672
-
Protein transduction from retroviral Gag precursors
-
Voelkel, C., Galla, M., Maetzig, T., Warlich, E., Kuehle, J., Zychlinski, D., Bode, J., Cantz, T., Schambach, A., and Baum, C. (2010). Protein transduction from retroviral Gag precursors. Proc. Natl. Acad. Sci. U.S.A. 107, 7805-7810.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 7805-7810
-
-
Voelkel, C.1
Galla, M.2
Maetzig, T.3
Warlich, E.4
Kuehle, J.5
Zychlinski, D.6
Bode, J.7
Cantz, T.8
Schambach, A.9
Baum, C.10
-
198
-
-
33846225133
-
Huntington's disease
-
Walker, F. O. (2007). Huntington's disease. Lancet 369, 218-228.
-
(2007)
Lancet
, vol.369
, pp. 218-228
-
-
Walker, F.O.1
-
199
-
-
77958536106
-
Highly efficient reprogramming to pluripo-tency and directed differentiation of human cells with synthetic modified mRNA
-
Warren, L., Manos, P. D., Ahfeldt, T., Loh, Y H., Li, H., Lau, F., Ebina, W., Mandal, P. K., Smith, Z. D., Meiss-ner, A., Daley, G. Q., Brack, A. S., Collins, J. J., Cowan, C., Schlaeger, T. M., and Rossi, D. J. (2010). Highly efficient reprogramming to pluripo-tency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7, 618-630.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
Ebina, W.7
Mandal, P.K.8
Smith, Z.D.9
Meiss-ner, A.10
Daley, G.Q.11
Brack, A.S.12
Collins, J.J.13
Cowan, C.14
Schlaeger, T.M.15
Rossi, D.J.16
-
200
-
-
14544296563
-
Directed differentiation of telen-cephalic precursors from embryonic stem cells
-
Watanabe, K., Kamiya, D., Nishiyama, A., Katayama, T., Nozaki, S., Kawasaki, H., Watanabe, Y., Mizuseki, K., and Sasai, Y. (2005). Directed differentiation of telen-cephalic precursors from embryonic stem cells. Nat. Neurosci. 8, 288-296.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 288-296
-
-
Watanabe, K.1
Kamiya, D.2
Nishiyama, A.3
Katayama, T.4
Nozaki, S.5
Kawasaki, H.6
Watanabe, Y.7
Mizuseki, K.8
Sasai, Y.9
-
201
-
-
34250206996
-
A ROCK inhibitor permits survival of dissociated human embryonic stem cells
-
Watanabe, K., Ueno, M., Kamiya, D., Nishiyama, A., Matsumura, M., Wataya, T., Takahashi, J. B., Nishikawa, S., Nishikawa, S. I., Muguruma, K., and Sasai, Y (2007). A ROCK inhibitor permits survival of dissociated human embryonic stem cells. Nat. Biotechnol. 25, 681-686.
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 681-686
-
-
Watanabe, K.1
Ueno, M.2
Kamiya, D.3
Nishiyama, A.4
Matsumura, M.5
Wataya, T.6
Takahashi, J.B.7
Nishikawa, S.8
Nishikawa, S.I.9
Muguruma, K.10
Sasai, Y.11
-
202
-
-
60149083711
-
Characterization of human embryonic stem cells with features of neoplastic progression
-
Werbowetski-Ogilvie, T. E., Bosse, M., Stewart, M., Schnerch, A., Ramos-Mejia, V., Rouleau, A., Wynder, T., Smith, M. J., Dingwall, S., Carter, T., Williams, C., Harris, C., Dolling, J., Wynder, C., Boreham, D., and Bha-tia, M. (2009). Characterization of human embryonic stem cells with features of neoplastic progression. Nat. Biotechnol. 27, 91-97.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 91-97
-
-
Werbowetski-Ogilvie, T.E.1
Bosse, M.2
Stewart, M.3
Schnerch, A.4
Ramos-Mejia, V.5
Rouleau, A.6
Wynder, T.7
Smith, M.J.8
Dingwall, S.9
Carter, T.10
Williams, C.11
Harris, C.12
Dolling, J.13
Wynder, C.14
Boreham, D.15
Bha-tia, M.16
-
203
-
-
37549008674
-
c-Myc is dispensable for direct reprogramming of mouse fibroblasts
-
Wernig, M., Meissner, A., Cassady, J. P., and Jaenisch, R. (2008). c-Myc is dispensable for direct reprogramming of mouse fibroblasts. Cell Stem Cell 2, 10-12.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 10-12
-
-
Wernig, M.1
Meissner, A.2
Cassady, J.P.3
Jaenisch, R.4
-
204
-
-
42649130264
-
Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
-
Wernig, M., Zhao, J. P., Pruszak, J., Hedlund, E., Fu, D., Soldner, E, Broccoli, V., Constantine-Paton, M., Isacson, O., and Jaenisch, R. (2008). Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease. Proc. Natl. Acad. Sci. U.S.A. 105, 5856-5861.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 5856-5861
-
-
Wernig, M.1
Zhao, J.P.2
Pruszak, J.3
Hedlund, E.4
Fu, D.5
Soldner, E.6
Broccoli, V.7
Constantine-Paton, M.8
Isacson, O.9
Jaenisch, R.10
-
205
-
-
0037047320
-
Directed differentiation of embryonic stem cells into motor neurons
-
Wichterle, H., Lieberam, I., Porter, J. A., and Jessell, T. M. (2002). Directed differentiation of embryonic stem cells into motor neurons. Cell 110, 385-397.
-
(2002)
Cell
, vol.110
, pp. 385-397
-
-
Wichterle, H.1
Lieberam, I.2
Porter, J.A.3
Jessell, T.M.4
-
206
-
-
79952579942
-
Neurodegenerative disease and adult neurogenesis
-
Winner, B., Kohl, Z., and Gage, F. H. (2011). Neurodegenerative disease and adult neurogenesis. Eur. J. Neurosci. 33, 1139-1151.
-
(2011)
Eur. J. Neurosci.
, vol.33
, pp. 1139-1151
-
-
Winner, B.1
Kohl, Z.2
Gage, F.H.3
-
207
-
-
64749083939
-
piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
-
Woltjen, K., Michael, I. P., Mohseni, P., Desai, R., Mileikovsky, M., Hamalainen, R., Cowling, R., Wang, W., Liu, P., Gertsenstein, M., Kaji, K., Sung, H. K., and Nagy, A. (2009). piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature 458, 766-770.
-
(2009)
Nature
, vol.458
, pp. 766-770
-
-
Woltjen, K.1
Michael, I.P.2
Mohseni, P.3
Desai, R.4
Mileikovsky, M.5
Hamalainen, R.6
Cowling, R.7
Wang, W.8
Liu, P.9
Gertsenstein, M.10
Kaji, K.11
Sung, H.K.12
Nagy, A.13
-
208
-
-
0034794417
-
Feeder-free growth of undifferentiated human embryonic stem cells
-
Xu, C., Inokuma, M. S., Denham, J., Golds, K., Kundu, P., Gold, J. D., and Carpenter, M. K. (2001). Feeder-free growth of undifferentiated human embryonic stem cells. Nat. Biotechnol. 19, 971-974.
-
(2001)
Nat. Biotechnol.
, vol.19
, pp. 971-974
-
-
Xu, C.1
Inokuma, M.S.2
Denham, J.3
Golds, K.4
Kundu, P.5
Gold, J.D.6
Carpenter, M.K.7
-
209
-
-
81255169342
-
Modeling familial Alzheimer's disease with induced pluripotent stem cells
-
Yagi, T., Ito, D., Okada, Y., Aka-matsu, W., Nihei, Y., Yoshizaki, T., Yamanaka, S., Okano, H., and Suzuki, N. (2011). Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum. Mol. Genet. 20,4530-4539.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 4530-4539
-
-
Yagi, T.1
Ito, D.2
Okada, Y.3
Aka-matsu, W.4
Nihei, Y.5
Yoshizaki, T.6
Yamanaka, S.7
Okano, H.8
Suzuki, N.9
-
210
-
-
77953466536
-
Nuclear reprogramming to a pluripotent state by three approaches
-
Yamanaka, S., and Blau, H. M. (2010). Nuclear reprogramming to a pluripotent state by three approaches. Nature 465, 704-712.
-
(2010)
Nature
, vol.465
, pp. 704-712
-
-
Yamanaka, S.1
Blau, H.M.2
-
211
-
-
20344368813
-
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells
-
Yan, Y., Yang, D., Zarnowska, E. D., Du, Z., Werbel, B., Valliere, C., Pearce, R. A., Thomson, J. A., and Zhang, S. C. (2005). Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 23, 781-790.
-
(2005)
Stem Cells
, vol.23
, pp. 781-790
-
-
Yan, Y.1
Yang, D.2
Zarnowska, E.D.3
Du, Z.4
Werbel, B.5
Valliere, C.6
Pearce, R.A.7
Thomson, J.A.8
Zhang, S.C.9
-
212
-
-
78650051022
-
Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome
-
Yang, J., Cai, J., Zhang, Y., Wang, X., Li, W., Xu, J., Li, F., Guo, X., Deng, K., Zhong, M., Chen, Y., Lai, L., Pei, D., and Esteban, M. A. (2010). Induced pluripotent stem cells can be used to model the genomic imprinting disorder Prader-Willi syndrome. J. Biol. Chem. 285, 40303-40311.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 40303-40311
-
-
Yang, J.1
Cai, J.2
Zhang, Y.3
Wang, X.4
Li, W.5
Xu, J.6
Li, F.7
Guo, X.8
Deng, K.9
Zhong, M.10
Chen, Y.11
Lai, L.12
Pei, D.13
Esteban, M.A.14
-
213
-
-
45349085487
-
Tumor progression of culture-adapted human embryonic stem cells during long-term culture
-
Yang, S., Lin, G., Tan, Y Q., Zhou, D., Deng, L. Y., Cheng, D. H., Luo, S. W., Liu, T. C., Zhou, X. Y., Sun, Z., Xiang, Y., Chen, T. J., Wen, J. F., and Lu, G. X. (2008). Tumor progression of culture-adapted human embryonic stem cells during long-term culture. Genes Chromosomes Cancer 47, 665-679.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 665-679
-
-
Yang, S.1
Lin, G.2
Tan, Y.Q.3
Zhou, D.4
Deng, L.Y.5
Cheng, D.H.6
Luo, S.W.7
Liu, T.C.8
Zhou, X.Y.9
Sun, Z.10
Xiang, Y.11
Chen, T.J.12
Wen, J.F.13
Lu, G.X.14
-
214
-
-
0037313844
-
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
-
Ying, Q. L., Stavridis, M., Griffiths, D., Li, M., and Smith, A. (2003). Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotech-nol.21, 183-186.
-
(2003)
Nat. Biotech-nol
, vol.21
, pp. 183-186
-
-
Ying, Q.L.1
Stavridis, M.2
Griffiths, D.3
Li, M.4
Smith, A.5
-
215
-
-
65649116572
-
Human induced pluripotent stem cells free of vector and transgene sequences
-
Yu, J., Hu, K., Smuga-Otto, K., Tian, S., Stewart, R., Slukvin, I.I., and Thomson, J. A. (2009). Human induced pluripotent stem cells free of vector and transgene sequences. Science 324, 797-801.
-
(2009)
Science
, vol.324
, pp. 797-801
-
-
Yu, J.1
Hu, K.2
Smuga-Otto, K.3
Tian, S.4
Stewart, R.5
Slukvin, I.I.6
Thomson, J.A.7
-
216
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J., Vodyanik, M. A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J. L., Tian, S., Nie, J., Jonsdottir, G. A., Ruotti, V., Stewart, R., Slukvin, I. I., and Thomson, J. A. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
Slukvin, I.I.11
Thomson, J.A.12
-
217
-
-
80054987997
-
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
-
Yusa, K., Rashid, S. T., Strick-Marchand, H., Varela, I., Liu, P. Q., Paschon, D. E., Miranda, E., Ordonez, A., Hannan, N. R. F., Rouhani, E J., Darche, S., Alexander, G., Marciniak, S. J., Fusaki, N., Hasegawa, M., Holmes, M. C., Di Santo, J. P., Lomas, D. A., Bradley, A., and Vallier, L. (2011). Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature 478, 391-394.
-
(2011)
Nature
, vol.478
, pp. 391-394
-
-
Yusa, K.1
Rashid, S.T.2
Strick-Marchand, H.3
Varela, I.4
Liu, P.Q.5
Paschon, D.E.6
Miranda, E.7
Ordonez, A.8
Hannan, N.R.F.9
Rouhani, E.J.10
Darche, S.11
Alexander, G.12
Marciniak, S.J.13
Fusaki, N.14
Hasegawa, M.15
Holmes, M.C.16
Di Santo, J.P.17
Lomas, D.A.18
Bradley, A.19
Vallier, L.20
more..
-
218
-
-
84873337576
-
Characterization of human Huntington's disease cell model from induced pluripotent stem cells
-
doi:10.1371/currents.RRN1193
-
Zhang, N., An, M. C., Montoro, D., and Ellerby, L. M. (2010). Characterization of human Huntington's disease cell model from induced pluripotent stem cells. PLoS Curr. 28, RRN1193. doi:10.1371/currents.RRN1193
-
(2010)
PLoS Curr
, vol.28
-
-
Zhang, N.1
An, M.C.2
Montoro, D.3
Ellerby, L.M.4
-
219
-
-
66049135249
-
Generation of induced pluripotent stem cells using recombinant proteins
-
Zhou, H., Wu, S., Joo, J. Y., Zhu, S., Han, D. W., Lin, T., Trauger, S., Bien, G., Yao, S., Zhu, Y., Siuz-dak, G., Schöler, H. R., Duan, L., and Ding, S. (2009). Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4, 381-384.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
Trauger, S.7
Bien, G.8
Yao, S.9
Zhu, Y.10
Siuz-dak, G.11
Schöler, H.R.12
Duan, L.13
Ding, S.14
-
220
-
-
79952898021
-
Investigating monogenic and complex diseases with pluripotent stem cells
-
Zhu, H., Lensch, M. W., Cahan, P., and Daley, G. Q. (2011). Investigating monogenic and complex diseases with pluripotent stem cells. Nat. Rev. Genet. 12, 266-275.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 266-275
-
-
Zhu, H.1
Lensch, M.W.2
Cahan, P.3
Daley, G.Q.4
-
221
-
-
67649170378
-
Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells
-
Zou, J., Maeder, M. L., Mali, P., Pruett-Miller, S. M., Thibodeau-Beganny, S., Chou, B. K., Chen, G., Ye, Z., Park, I. H., Daley, G. Q., Porteus, M. H., Joung, J. K., and Cheng, L. (2009). Gene targeting of a disease-related gene in human induced pluripotent stem and embryonic stem cells. Cell Stem Cell. 5, 97-110.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 97-110
-
-
Zou, J.1
Maeder, M.L.2
Mali, P.3
Pruett-Miller, S.M.4
Thibodeau-Beganny, S.5
Chou, B.K.6
Chen, G.7
Ye, Z.8
Park, I.H.9
Daley, G.Q.10
Porteus, M.H.11
Joung, J.K.12
Cheng, L.13
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