메뉴 건너뛰기




Volumn 215, Issue 4, 2008, Pages 355-368

Neural commitment of embryonic stem cells: Molecules, pathways and potential for cell therapy

Author keywords

Cell therapy; Embryonic stem cells; Growth factors; Neuronal differentiation; Small molecules

Indexed keywords

CELL DIFFERENTIATION; CENTRAL NERVOUS SYSTEM DISEASE; EMBRYONIC STEM CELL; GLIA; HUMAN; IN VITRO STUDY; NERVOUS SYSTEM DEVELOPMENT; NEURAL STEM CELL; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; REGENERATIVE MEDICINE; REVIEW; STEM CELL TRANSPLANTATION; TECHNIQUE;

EID: 49449102627     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2380     Document Type: Review
Times cited : (34)

References (120)
  • 2
    • 33750632535 scopus 로고    scopus 로고
    • Neural induction: 10 years on since the 'default model'
    • Stern CD. Neural induction: 10 years on since the 'default model'. Curr Opin Cell Biol 2006;18:692-697.
    • (2006) Curr Opin Cell Biol , vol.18 , pp. 692-697
    • Stern, C.D.1
  • 3
    • 3242723843 scopus 로고    scopus 로고
    • Lineage development and polar asymmetries in the peri-implantation mouse blastocyst
    • Rossant J. Lineage development and polar asymmetries in the peri-implantation mouse blastocyst. Semin Cell Dev Biol 2004;15:573-581.
    • (2004) Semin Cell Dev Biol , vol.15 , pp. 573-581
    • Rossant, J.1
  • 4
    • 15744401970 scopus 로고    scopus 로고
    • Conserved patterns of cell movements during vertebrate gastrulation
    • Solnica-Krezel L. Conserved patterns of cell movements during vertebrate gastrulation. Curr Biol 2005;15:R213-228.
    • (2005) Curr Biol , vol.15
    • Solnica-Krezel, L.1
  • 5
    • 33646726733 scopus 로고    scopus 로고
    • Notch promotes neural lineage entry by pluripotent embryonic stem cells
    • Lowell S, Benchoua A, Heavey B, Smith AG. Notch promotes neural lineage entry by pluripotent embryonic stem cells. PLoS Biol 2006;4:e121.
    • (2006) PLoS Biol , vol.4
    • Lowell, S.1    Benchoua, A.2    Heavey, B.3    Smith, A.G.4
  • 6
    • 0037313844 scopus 로고    scopus 로고
    • Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    • Ying QL, Stavridis M, Griffiths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 2003;21:183-186.
    • (2003) Nat Biotechnol , vol.21 , pp. 183-186
    • Ying, Q.L.1    Stavridis, M.2    Griffiths, D.3    Li, M.4    Smith, A.5
  • 7
    • 23244432429 scopus 로고    scopus 로고
    • BMP signalling and stem cell regulation
    • Zhang J, Li L. BMP signalling and stem cell regulation. Dev Biol 2005;284:1-11.
    • (2005) Dev Biol , vol.284 , pp. 1-11
    • Zhang, J.1    Li, L.2
  • 8
    • 30644458570 scopus 로고    scopus 로고
    • Balancing cell adhesion and Wnt signalling; the key role of β-catenin
    • Brembeck FH, Rosario M, Birchmeier W. Balancing cell adhesion and Wnt signalling; the key role of β-catenin. Curr Opin Genet Dev 2006;16:51-59.
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 51-59
    • Brembeck, F.H.1    Rosario, M.2    Birchmeier, W.3
  • 9
    • 19744364989 scopus 로고    scopus 로고
    • Neural induction: Old problem, new findings, yet more questions
    • Stern CD. Neural induction: old problem, new findings, yet more questions. Development 2005;132:2007-2021.
    • (2005) Development , vol.132 , pp. 2007-2021
    • Stern, C.D.1
  • 10
    • 34248139757 scopus 로고    scopus 로고
    • The Hes gene family: Repressors and oscillators that orchestrate embryogenesis
    • Kageyama R, Ohtsuka T, Kobayashi T. The Hes gene family: repressors and oscillators that orchestrate embryogenesis. Development 2007;134:1243-1251.
    • (2007) Development , vol.134 , pp. 1243-1251
    • Kageyama, R.1    Ohtsuka, T.2    Kobayashi, T.3
  • 11
    • 32244438527 scopus 로고    scopus 로고
    • Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1
    • Takemoto T, Uchikawa M, Kamachi Y, Kondoh H. Convergence of Wnt and FGF signals in the genesis of posterior neural plate through activation of the Sox2 enhancer N-1. Development 2006;133:297-306.
    • (2006) Development , vol.133 , pp. 297-306
    • Takemoto, T.1    Uchikawa, M.2    Kamachi, Y.3    Kondoh, H.4
  • 12
    • 13844250648 scopus 로고    scopus 로고
    • SOX genes and neural progenitor identity
    • Pevny L, Placzek M. SOX genes and neural progenitor identity. Curr Opin Neurobiol 2005;15:7-13.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 7-13
    • Pevny, L.1    Placzek, M.2
  • 13
    • 7244242408 scopus 로고    scopus 로고
    • SoxB transcription factors specify neuroectodermal lineage choice in ES cells
    • Zhao S, Nichols J, Smith AG, Li M. SoxB transcription factors specify neuroectodermal lineage choice in ES cells. Mol Cell Neurosci 2004;27:332-342.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 332-342
    • Zhao, S.1    Nichols, J.2    Smith, A.G.3    Li, M.4
  • 14
    • 0037023492 scopus 로고    scopus 로고
    • The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification
    • Zhou Q, Anderson DJ. The bHLH transcription factors OLIG2 and OLIG1 couple neuronal and glial subtype specification. Cell 2002;109:61-73.
    • (2002) Cell , vol.109 , pp. 61-73
    • Zhou, Q.1    Anderson, D.J.2
  • 15
    • 0036920566 scopus 로고    scopus 로고
    • Induction and patterning of the telencephalon in Xenopus laevis
    • Lupo G, Harris WA, Barsacchi G, Vignali R. Induction and patterning of the telencephalon in Xenopus laevis. Development 2002;129:5421- 5436.
    • (2002) Development , vol.129 , pp. 5421-5436
    • Lupo, G.1    Harris, W.A.2    Barsacchi, G.3    Vignali, R.4
  • 16
    • 0032556910 scopus 로고    scopus 로고
    • Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
    • Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 1998;391:357-362.
    • (1998) Nature , vol.391 , pp. 357-362
    • Glinka, A.1    Wu, W.2    Delius, H.3    Monaghan, A.P.4    Blumenstock, C.5    Niehrs, C.6
  • 17
    • 0026759308 scopus 로고
    • Nested expression domains of four homeobox genes in developing rostral brain
    • Simeone A, Acampora D, Gulisano M, Stornaiuolo A, Boncinelli E. Nested expression domains of four homeobox genes in developing rostral brain. Nature 1992;358:687-690.
    • (1992) Nature , vol.358 , pp. 687-690
    • Simeone, A.1    Acampora, D.2    Gulisano, M.3    Stornaiuolo, A.4    Boncinelli, E.5
  • 18
    • 0001007610 scopus 로고
    • Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA 1981;78:7634-7638.
    • (1981) Proc Natl Acad Sci USA , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 21
    • 0018591935 scopus 로고
    • A procedure for purifying neuron-like cells in cultures from central nervous tissue with a defined medium
    • Skaper SD, Adler R, Varon S. A procedure for purifying neuron-like cells in cultures from central nervous tissue with a defined medium. Dev Neurosci 1979;2:233-237.
    • (1979) Dev Neurosci , vol.2 , pp. 233-237
    • Skaper, S.D.1    Adler, R.2    Varon, S.3
  • 22
    • 0023103339 scopus 로고
    • Brain neurons develop in a serum and glial free environment: Effects of transferrin, insulin, insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation
    • Aizenman Y, de Vellis J. Brain neurons develop in a serum and glial free environment: effects of transferrin, insulin, insulin-like growth factor-I and thyroid hormone on neuronal survival, growth and differentiation. Brain Res 1987;406:32-42.
    • (1987) Brain Res , vol.406 , pp. 32-42
    • Aizenman, Y.1    de Vellis, J.2
  • 23
    • 0037104645 scopus 로고    scopus 로고
    • Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro
    • Cai D, Deng K, Mellado W, Lee J, Ratan RR, Filbin MT. Arginase I and polyamines act downstream from cyclic AMP in overcoming inhibition of axonal growth MAG and myelin in vitro. Neuron 2002;35:711-719.
    • (2002) Neuron , vol.35 , pp. 711-719
    • Cai, D.1    Deng, K.2    Mellado, W.3    Lee, J.4    Ratan, R.R.5    Filbin, M.T.6
  • 24
    • 0023836269 scopus 로고
    • Early polyamine treatment enhances survival of sympathetic neurons after postnatal axonal injury or immunosympathectomy
    • Gilad GM, Gilad VH. Early polyamine treatment enhances survival of sympathetic neurons after postnatal axonal injury or immunosympathectomy. Brain Res 1988;466:175-181.
    • (1988) Brain Res , vol.466 , pp. 175-181
    • Gilad, G.M.1    Gilad, V.H.2
  • 25
    • 0029950597 scopus 로고    scopus 로고
    • Accelerated recovery following polyamines and aminoguanidine treatment after facial nerve injury in rats
    • Gilad VH, Tetzlaff WG, Rabey JM, Gilad GM. Accelerated recovery following polyamines and aminoguanidine treatment after facial nerve injury in rats. Brain Res 1996;724:141-144.
    • (1996) Brain Res , vol.724 , pp. 141-144
    • Gilad, V.H.1    Tetzlaff, W.G.2    Rabey, J.M.3    Gilad, G.M.4
  • 26
    • 0019961369 scopus 로고
    • Ornithine decarboxylase and polyamines in tissues of the neonatal rat: Effects of α-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase
    • Slotkin TA, Seidler FJ, Trepanier PA, Whitmore WL, Lerea L, Barnes GA, et al. Ornithine decarboxylase and polyamines in tissues of the neonatal rat: effects of α-difluoromethylornithine, a specific, irreversible inhibitor of ornithine decarboxylase. J Pharmacol Exp Ther 1982;222:741-745.
    • (1982) J Pharmacol Exp Ther , vol.222 , pp. 741-745
    • Slotkin, T.A.1    Seidler, F.J.2    Trepanier, P.A.3    Whitmore, W.L.4    Lerea, L.5    Barnes, G.A.6
  • 27
    • 0031564631 scopus 로고    scopus 로고
    • Polyamines prevent apoptotic cell death in cultured cerebellar granule neurons
    • Harada J, Sugimoto M. Polyamines prevent apoptotic cell death in cultured cerebellar granule neurons. Brain Res 1997;753:251-259.
    • (1997) Brain Res , vol.753 , pp. 251-259
    • Harada, J.1    Sugimoto, M.2
  • 29
    • 0032213309 scopus 로고    scopus 로고
    • Purification from bovine serum of a survival-promoting factor for cultured central neurons and its identification as selenoprotein-P
    • Yan J, Barrett JN. Purification from bovine serum of a survival-promoting factor for cultured central neurons and its identification as selenoprotein-P. J Neurosci 1998;18:8682-8691.
    • (1998) J Neurosci , vol.18 , pp. 8682-8691
    • Yan, J.1    Barrett, J.N.2
  • 30
    • 0036141071 scopus 로고    scopus 로고
    • Impact of progestins on estrogen-induced neuroprotection: Synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate
    • Nilsen J, Brinton RD. Impact of progestins on estrogen-induced neuroprotection: synergy by progesterone and 19-norprogesterone and antagonism by medroxyprogesterone acetate. Endocrinology 2002;143:205-212.
    • (2002) Endocrinology , vol.143 , pp. 205-212
    • Nilsen, J.1    Brinton, R.D.2
  • 31
    • 0028868824 scopus 로고
    • Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus
    • Brewer GJ. Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus. J Neurosci Res 1995;42:674-683.
    • (1995) J Neurosci Res , vol.42 , pp. 674-683
    • Brewer, G.J.1
  • 33
    • 33846971644 scopus 로고    scopus 로고
    • Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures
    • Nat R, Nilbratt M, Narkilahti S, Winblad B, Hovatta O, Nordberg A. Neurogenic neuroepithelial and radial glial cells generated from six human embryonic stem cell lines in serum-free suspension and adherent cultures. Glia 2007;55:385-399.
    • (2007) Glia , vol.55 , pp. 385-399
    • Nat, R.1    Nilbratt, M.2    Narkilahti, S.3    Winblad, B.4    Hovatta, O.5    Nordberg, A.6
  • 34
    • 25844465546 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signalling
    • Gerrard L, Rodgers L, Cui W. Differentiation of human embryonic stem cells to neural lineages in adherent culture by blocking bone morphogenetic protein signalling. Stem Cells 2005;23:1234-1241.
    • (2005) Stem Cells , vol.23 , pp. 1234-1241
    • Gerrard, L.1    Rodgers, L.2    Cui, W.3
  • 35
    • 0030248408 scopus 로고    scopus 로고
    • Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro
    • Okabe S, Forsberg-Nilsson K, Spiro AC, Segal M, McKay RD. Development of neuronal precursor cells and functional postmitotic neurons from embryonic stem cells in vitro. Mech Dev 1996;59:89-102.
    • (1996) Mech Dev , vol.59 , pp. 89-102
    • Okabe, S.1    Forsberg-Nilsson, K.2    Spiro, A.C.3    Segal, M.4    McKay, R.D.5
  • 36
    • 29944443025 scopus 로고    scopus 로고
    • Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences
    • Smukler SR, Runciman SB, Xu S, van der Kooy D. Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences. J Cell Biol 2006;172:79-90.
    • (2006) J Cell Biol , vol.172 , pp. 79-90
    • Smukler, S.R.1    Runciman, S.B.2    Xu, S.3    van der Kooy, D.4
  • 38
    • 0035025619 scopus 로고    scopus 로고
    • Direct neural fate specification from embryonic stem cells: A primitive mammalian neural stem cell stage acquired through a default mechanism
    • Tropepe V, Hitoshi S, Sirard C, Mak TW, Rossant J, van der Kooy D. Direct neural fate specification from embryonic stem cells: a primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron 2001;30:65-78.
    • (2001) Neuron , vol.30 , pp. 65-78
    • Tropepe, V.1    Hitoshi, S.2    Sirard, C.3    Mak, T.W.4    Rossant, J.5    van der Kooy, D.6
  • 39
    • 33745012950 scopus 로고    scopus 로고
    • Neural subtype specification from embryonic stem cells
    • Zhang SC. Neural subtype specification from embryonic stem cells. Brain Pathol 2006;16:132-142.
    • (2006) Brain Pathol , vol.16 , pp. 132-142
    • Zhang, S.C.1
  • 40
    • 10744229091 scopus 로고    scopus 로고
    • Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
    • Barberi T, Klivenyi P, Calingasan NY, Lee H, Kawamata H, Loonam K, et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 2003;21:1200-1207.
    • (2003) Nat Biotechnol , vol.21 , pp. 1200-1207
    • Barberi, T.1    Klivenyi, P.2    Calingasan, N.Y.3    Lee, H.4    Kawamata, H.5    Loonam, K.6
  • 42
    • 10444246723 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture
    • Schulz TC, Noggle SA, Palmarini GM, Weiler DA, Lyons IG, Pensa KA, et al. Differentiation of human embryonic stem cells to dopaminergic neurons in serum-free suspension culture. Stem Cells 2004;22:1218-1238.
    • (2004) Stem Cells , vol.22 , pp. 1218-1238
    • Schulz, T.C.1    Noggle, S.A.2    Palmarini, G.M.3    Weiler, D.A.4    Lyons, I.G.5    Pensa, K.A.6
  • 43
    • 85047689727 scopus 로고    scopus 로고
    • Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model
    • Takagi Y, Takahashi J, Saiki H, Morizane A, Hayashi T, Kishi Y, et al. Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model. J Clin Invest 2005;115:102-109.
    • (2005) J Clin Invest , vol.115 , pp. 102-109
    • Takagi, Y.1    Takahashi, J.2    Saiki, H.3    Morizane, A.4    Hayashi, T.5    Kishi, Y.6
  • 44
    • 33749041337 scopus 로고    scopus 로고
    • Induction of midbrain dopaminergic neurons from primate embryonic stem cells by co-culture with Sertoli cells
    • Yue F, Cui L, Johkura K, Ogiwara N, Sasaki K. Induction of midbrain dopaminergic neurons from primate embryonic stem cells by co-culture with Sertoli cells. Stem Cells 2006;24:1695-1706.
    • (2006) Stem Cells , vol.24 , pp. 1695-1706
    • Yue, F.1    Cui, L.2    Johkura, K.3    Ogiwara, N.4    Sasaki, K.5
  • 46
    • 34547858511 scopus 로고    scopus 로고
    • Directed differentiation and transplantation of human embryonic stem cell-derived motor neurons
    • Lee H, Shamy GA, Elkabetz Y, Schofield CM, Harrsion NL, Panagiotakos G, et al. Directed differentiation and transplantation of human embryonic stem cell-derived motor neurons. Stem Cells 2007;25:1931-1939.
    • (2007) Stem Cells , vol.25 , pp. 1931-1939
    • Lee, H.1    Shamy, G.A.2    Elkabetz, Y.3    Schofield, C.M.4    Harrsion, N.L.5    Panagiotakos, G.6
  • 47
    • 0026550179 scopus 로고
    • Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motor neurons in vitro
    • Martinou JC, Martinou I, Kato AC. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motor neurons in vitro. Neuron 1992;8:737-744.
    • (1992) Neuron , vol.8 , pp. 737-744
    • Martinou, J.C.1    Martinou, I.2    Kato, A.C.3
  • 48
    • 33846909499 scopus 로고    scopus 로고
    • Efficient induction of oligodendrocytes from human embryonic stem cells
    • Kang SM, Cho MS, Seo H, Yoon CJ, Oh SK, Choi YM, et al. Efficient induction of oligodendrocytes from human embryonic stem cells. Stem Cells 2007;25:419-424.
    • (2007) Stem Cells , vol.25 , pp. 419-424
    • Kang, S.M.1    Cho, M.S.2    Seo, H.3    Yoon, C.J.4    Oh, S.K.5    Choi, Y.M.6
  • 49
    • 33847678638 scopus 로고    scopus 로고
    • Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation
    • Chen SS, Fitzgerald W, Zimmerberg J, Kleinman HK, Margolis L. Cell-cell and cell-extracellular matrix interactions regulate embryonic stem cell differentiation. Stem Cells 2007;25:553-561.
    • (2007) Stem Cells , vol.25 , pp. 553-561
    • Chen, S.S.1    Fitzgerald, W.2    Zimmerberg, J.3    Kleinman, H.K.4    Margolis, L.5
  • 51
    • 33746642085 scopus 로고    scopus 로고
    • Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells
    • Goetz AK, Scheffler B, Chen HX, Wang S, Suslov O, Xiang H, et al. Temporally restricted substrate interactions direct fate and specification of neural precursors derived from embryonic stem cells. Proc Natl Acad Sci USA 2006;103:11063-11068.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 11063-11068
    • Goetz, A.K.1    Scheffler, B.2    Chen, H.X.3    Wang, S.4    Suslov, O.5    Xiang, H.6
  • 53
    • 0033638174 scopus 로고    scopus 로고
    • Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
    • Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 2000;28:31-40.
    • (2000) Neuron , vol.28 , pp. 31-40
    • Kawasaki, H.1    Mizuseki, K.2    Nishikawa, S.3    Kaneko, S.4    Kuwana, Y.5    Nakanishi, S.6
  • 54
    • 0023001022 scopus 로고
    • MC3T3-G2/PA6 preadipocytes support in vitro proliferation of hemopoietic stem cells through a mechanism different from that of interleukin 3
    • Kodama H, Hagiwara H, Sudo H, Amagai Y, Yokota T, Arai N, et al. MC3T3-G2/PA6 preadipocytes support in vitro proliferation of hemopoietic stem cells through a mechanism different from that of interleukin 3. J Cell Physiol 1986;129:20-26.
    • (1986) J Cell Physiol , vol.129 , pp. 20-26
    • Kodama, H.1    Hagiwara, H.2    Sudo, H.3    Amagai, Y.4    Yokota, T.5    Arai, N.6
  • 55
    • 0037022299 scopus 로고    scopus 로고
    • Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity
    • Kawasaki H, Suemori H, Mizuseki K, Watanabe K, Urano F, Ichinose H, et al. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci USA 2002;99:1580-1585.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1580-1585
    • Kawasaki, H.1    Suemori, H.2    Mizuseki, K.3    Watanabe, K.4    Urano, F.5    Ichinose, H.6
  • 56
    • 33646771766 scopus 로고    scopus 로고
    • Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells
    • Guo XM, Zhao YS, Chang HX, Wang CY, E LL, Zhang XA, et al. Creation of engineered cardiac tissue in vitro from mouse embryonic stem cells. Circulation 2006;113:2229-2237.
    • (2006) Circulation , vol.113 , pp. 2229-2237
    • Guo, X.M.1    Zhao, Y.S.2    Chang, H.X.3    Wang4    CY, E.L.5    Zhang, X.A.6
  • 57
    • 33845647995 scopus 로고    scopus 로고
    • Embryonic stem cells utilize reactive oxygen species as transducers of mechanical strain-induced cardiovascular differentiation
    • Schmelter M, Ateghang B, Helmig S, Wartenberg M, Sauer H. Embryonic stem cells utilize reactive oxygen species as transducers of mechanical strain-induced cardiovascular differentiation. FASEB J 2006;20:1182-1184.
    • (2006) FASEB J , vol.20 , pp. 1182-1184
    • Schmelter, M.1    Ateghang, B.2    Helmig, S.3    Wartenberg, M.4    Sauer, H.5
  • 58
    • 23744442185 scopus 로고    scopus 로고
    • Differentiation from embryonic stem cells to vascular wall cells under in vitro pulsatile flow loading
    • Huang H, Nakayama Y, Qin K, Yamamoto K, Ando J, Yamashita J, et al. Differentiation from embryonic stem cells to vascular wall cells under in vitro pulsatile flow loading. J Artif Organs 2005;8:110-118.
    • (2005) J Artif Organs , vol.8 , pp. 110-118
    • Huang, H.1    Nakayama, Y.2    Qin, K.3    Yamamoto, K.4    Ando, J.5    Yamashita, J.6
  • 59
    • 33646249946 scopus 로고    scopus 로고
    • Effect of oxygen on in vitro differentiation of mouse embryonic stem cells
    • Kurosawa H, Kimura M, Noda T, Amano Y. Effect of oxygen on in vitro differentiation of mouse embryonic stem cells. J Biosci Bioeng 2006;101:26-30.
    • (2006) J Biosci Bioeng , vol.101 , pp. 26-30
    • Kurosawa, H.1    Kimura, M.2    Noda, T.3    Amano, Y.4
  • 60
    • 33847638153 scopus 로고    scopus 로고
    • Electrical stimulation modulates fate determination of differentiating embryonic stem cells
    • Yamada M, Tanemura K, Okada S, Iwanami A, Nakamura M, Mizuno H, et al. Electrical stimulation modulates fate determination of differentiating embryonic stem cells. Stem Cells 2007;25:562-570.
    • (2007) Stem Cells , vol.25 , pp. 562-570
    • Yamada, M.1    Tanemura, K.2    Okada, S.3    Iwanami, A.4    Nakamura, M.5    Mizuno, H.6
  • 61
    • 33745396456 scopus 로고    scopus 로고
    • Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells
    • Ben-Dor I, Itsykson P, Goldenberg D, Galun E, Reubinoff BE. Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells. Mol Ther 2006;14:255-267.
    • (2006) Mol Ther , vol.14 , pp. 255-267
    • Ben-Dor, I.1    Itsykson, P.2    Goldenberg, D.3    Galun, E.4    Reubinoff, B.E.5
  • 62
  • 64
    • 0036835342 scopus 로고    scopus 로고
    • Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons
    • Chung S, Sonntag KC, Andersson T, Bjorklund LM, Park JJ, Kim DW, et al. Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons. Eur J Neurosci 2002;16:1829-1838.
    • (2002) Eur J Neurosci , vol.16 , pp. 1829-1838
    • Chung, S.1    Sonntag, K.C.2    Andersson, T.3    Bjorklund, L.M.4    Park, J.J.5    Kim, D.W.6
  • 65
    • 33750534954 scopus 로고    scopus 로고
    • Establishment of the gene-inducible system in primate embryonic stem cell lines
    • Adachi K, Kawase E, Yasuchika K, Sumi T, Nakatsuji N, Suemori H. Establishment of the gene-inducible system in primate embryonic stem cell lines. Stem Cells 2006;24:2566-2572.
    • (2006) Stem Cells , vol.24 , pp. 2566-2572
    • Adachi, K.1    Kawase, E.2    Yasuchika, K.3    Sumi, T.4    Nakatsuji, N.5    Suemori, H.6
  • 66
    • 33847642244 scopus 로고    scopus 로고
    • Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer
    • Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L. Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer. Stem Cells 2007;25:779-789.
    • (2007) Stem Cells , vol.25 , pp. 779-789
    • Zhou, B.Y.1    Ye, Z.2    Chen, G.3    Gao, Z.P.4    Zhang, Y.A.5    Cheng, L.6
  • 67
    • 49449109903 scopus 로고    scopus 로고
    • A tetracycline-inducible lentivector system based on EF1-α promoter and native tetracycline repressor allows in vivo gene induction in implanted ES cells
    • Suter DM, Montet X, Tirefort D, Cartier L, Krause KH. A tetracycline-inducible lentivector system based on EF1-α promoter and native tetracycline repressor allows in vivo gene induction in implanted ES cells. J Stem Cells 2007; 2:73-90.
    • (2007) J Stem Cells , vol.2 , pp. 73-90
    • Suter, D.M.1    Montet, X.2    Tirefort, D.3    Cartier, L.4    Krause, K.H.5
  • 68
    • 0141483083 scopus 로고    scopus 로고
    • Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice
    • Aubert J, Stavridis MP, Tweedie S, O'Reilly M, Vierlinger K, Li M, et al. Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice. Proc Natl Acad Sci USA 2003;100(suppl 1):11836-11841.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.SUPPL. 1 , pp. 11836-11841
    • Aubert, J.1    Stavridis, M.P.2    Tweedie, S.3    O'Reilly, M.4    Vierlinger, K.5    Li, M.6
  • 70
    • 27744438009 scopus 로고    scopus 로고
    • Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells
    • Singh Roy N, Nakano T, Xuing L, Kang J, Nedergaard M, Goldman SA. Enhancer-specified GFP-based FACS purification of human spinal motor neurons from embryonic stem cells. Exp Neurol 2005;196:224-234.
    • (2005) Exp Neurol , vol.196 , pp. 224-234
    • Singh Roy, N.1    Nakano, T.2    Xuing, L.3    Kang, J.4    Nedergaard, M.5    Goldman, S.A.6
  • 71
    • 33749367585 scopus 로고    scopus 로고
    • Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium
    • Kolossov E, Bostani T, Roell W, Breitbach M, Pillekamp F, Nygren JM, et al. Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium. J Exp Med 2006;203:2315-2327.
    • (2006) J Exp Med , vol.203 , pp. 2315-2327
    • Kolossov, E.1    Bostani, T.2    Roell, W.3    Breitbach, M.4    Pillekamp, F.5    Nygren, J.M.6
  • 72
    • 0034044317 scopus 로고    scopus 로고
    • Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
    • Lee SH, Lumelsky N, Studer L, Auerbach JM, McKay RD. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 2000;18:675-679.
    • (2000) Nat Biotechnol , vol.18 , pp. 675-679
    • Lee, S.H.1    Lumelsky, N.2    Studer, L.3    Auerbach, J.M.4    McKay, R.D.5
  • 75
    • 33947583867 scopus 로고    scopus 로고
    • NO-cGMP signalling and regenerative medicine involving stem cells
    • Madhusoodanan KS, Murad F. NO-cGMP signalling and regenerative medicine involving stem cells. Neurochem Res 2007;32:681-694.
    • (2007) Neurochem Res , vol.32 , pp. 681-694
    • Madhusoodanan, K.S.1    Murad, F.2
  • 76
    • 5644276383 scopus 로고    scopus 로고
    • Delivery of bioactive molecules into the cell: The Trojan horse approach
    • Dietz GP, Bahr M. Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol Cell Neurosci 2004;27:85-131.
    • (2004) Mol Cell Neurosci , vol.27 , pp. 85-131
    • Dietz, G.P.1    Bahr, M.2
  • 77
    • 0344413639 scopus 로고    scopus 로고
    • In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein
    • Krosl J, Austin P, Beslu N, Kroon E, Humphries RK, Sauvageau G. In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein. Nat Med 2003;9:1428-1432.
    • (2003) Nat Med , vol.9 , pp. 1428-1432
    • Krosl, J.1    Austin, P.2    Beslu, N.3    Kroon, E.4    Humphries, R.K.5    Sauvageau, G.6
  • 78
    • 20844449780 scopus 로고    scopus 로고
    • Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction
    • Kwon YD, Oh SK, Kim HS, Ku SY, Kim SH, Choi YM, et al. Cellular manipulation of human embryonic stem cells by TAT-PDX1 protein transduction. Mol Ther 2005;12:28-32.
    • (2005) Mol Ther , vol.12 , pp. 28-32
    • Kwon, Y.D.1    Oh, S.K.2    Kim, H.S.3    Ku, S.Y.4    Kim, S.H.5    Choi, Y.M.6
  • 79
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Adv Drug Deliv Rev 2001;46:3-26.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 80
    • 0037446546 scopus 로고    scopus 로고
    • Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes
    • Takahashi T, Lord B, Schulze PC, Fryer RM, Sarang SS, Gullans SR, et al. Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes. Circulation 2003;107:1912-1916.
    • (2003) Circulation , vol.107 , pp. 1912-1916
    • Takahashi, T.1    Lord, B.2    Schulze, P.C.3    Fryer, R.M.4    Sarang, S.S.5    Gullans, S.R.6
  • 81
    • 33645523196 scopus 로고    scopus 로고
    • Exploring stem cell biology with small molecules
    • Chen S, Hilcove S, Ding S. Exploring stem cell biology with small molecules. Mol Biosyst 2006;2:18-24.
    • (2006) Mol Biosyst , vol.2 , pp. 18-24
    • Chen, S.1    Hilcove, S.2    Ding, S.3
  • 84
    • 20344382031 scopus 로고    scopus 로고
    • No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses
    • Amit M, Winkler ME, Menke S, Bruning E, Buscher K, Denner J, et al. No evidence for infection of human embryonic stem cells by feeder cell-derived murine leukemia viruses. Stem Cells 2005;23:761-771.
    • (2005) Stem Cells , vol.23 , pp. 761-771
    • Amit, M.1    Winkler, M.E.2    Menke, S.3    Bruning, E.4    Buscher, K.5    Denner, J.6
  • 85
    • 13844267152 scopus 로고    scopus 로고
    • Human embryonic stem cells express an immunogenic nonhuman sialic acid
    • Martin MJ, Muotri A, Gage F, Varki A. Human embryonic stem cells express an immunogenic nonhuman sialic acid. Nat Med 2005;11:228-232.
    • (2005) Nat Med , vol.11 , pp. 228-232
    • Martin, M.J.1    Muotri, A.2    Gage, F.3    Varki, A.4
  • 87
    • 33646474117 scopus 로고    scopus 로고
    • Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions
    • Yao S, Chen S, Clark J, Hao E, Beattie GM, Hayek A, et al. Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. Proc Natl Acad Sci USA 2006;103:6907-6912.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6907-6912
    • Yao, S.1    Chen, S.2    Clark, J.3    Hao, E.4    Beattie, G.M.5    Hayek, A.6
  • 89
    • 33745108790 scopus 로고    scopus 로고
    • Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration
    • Montini E, Cesana D, Schmidt M, Sanvito F, Ponzoni M, Bartholomae C, et al. Hematopoietic stem cell gene transfer in a tumor-prone mouse model uncovers low genotoxicity of lentiviral vector integration. Nat Biotechnol 2006;24:687-696.
    • (2006) Nat Biotechnol , vol.24 , pp. 687-696
    • Montini, E.1    Cesana, D.2    Schmidt, M.3    Sanvito, F.4    Ponzoni, M.5    Bartholomae, C.6
  • 90
    • 34250851635 scopus 로고    scopus 로고
    • Comparison of HIV-derived lentiviral and MLV-based gamma;-retroviral vector integration sites in primate repopulating cells
    • Beard BC, Dickerson D, Beebe K, Gooch C, Fletcher J, Okbinoglu T, et al. Comparison of HIV-derived lentiviral and MLV-based gamma;-retroviral vector integration sites in primate repopulating cells. Mol Ther 2007;1356-1365.
    • (2007) Mol Ther , pp. 1356-1365
    • Beard, B.C.1    Dickerson, D.2    Beebe, K.3    Gooch, C.4    Fletcher, J.5    Okbinoglu, T.6
  • 92
    • 4344601961 scopus 로고    scopus 로고
    • Differentiation of mouse embryonic stem cells into a defined neuronal lineage
    • Bibel M, Richter J, Schrenk K, Tucker KL, Staiger V, Korte M, et al. Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nat Neurosci 2004;7:1003-1009.
    • (2004) Nat Neurosci , vol.7 , pp. 1003-1009
    • Bibel, M.1    Richter, J.2    Schrenk, K.3    Tucker, K.L.4    Staiger, V.5    Korte, M.6
  • 93
    • 0038700553 scopus 로고    scopus 로고
    • Selective ablation of human embryonic stem cells expressing a 'suicide' gene
    • Schuldiner M, Itskovitz-Eldor J, Benvenisty N. Selective ablation of human embryonic stem cells expressing a 'suicide' gene. Stem Cells 2003;21:257-265.
    • (2003) Stem Cells , vol.21 , pp. 257-265
    • Schuldiner, M.1    Itskovitz-Eldor, J.2    Benvenisty, N.3
  • 94
    • 33750706917 scopus 로고    scopus 로고
    • Functional engraftment of human ES cell-derived dopaminergic neurons enriched by co-culture with telomerase-immortalized midbrain astrocytes
    • Roy NS, Cleren C, Singh SK, Yang L, Beal MF, Goldman SA. Functional engraftment of human ES cell-derived dopaminergic neurons enriched by co-culture with telomerase-immortalized midbrain astrocytes. Nat Med 2006;12:1259-1268.
    • (2006) Nat Med , vol.12 , pp. 1259-1268
    • Roy, N.S.1    Cleren, C.2    Singh, S.K.3    Yang, L.4    Beal, M.F.5    Goldman, S.A.6
  • 95
    • 22444450988 scopus 로고    scopus 로고
    • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism
    • Pluchino S, Zanotti L, Rossi B, Brambilla E, Ottoboni L, Salani G, et al. Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism. Nature 2005;436:266-271.
    • (2005) Nature , vol.436 , pp. 266-271
    • Pluchino, S.1    Zanotti, L.2    Rossi, B.3    Brambilla, E.4    Ottoboni, L.5    Salani, G.6
  • 96
    • 0021000270 scopus 로고
    • Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites
    • Bjorklund A, Stenevi U, Schmidt RH, Dunnett SB, Gage FH. Intracerebral grafting of neuronal cell suspensions. II. Survival and growth of nigral cell suspensions implanted in different brain sites. Acta Physiol Scand Suppl 1983;522:9-18.
    • (1983) Acta Physiol Scand Suppl , vol.522 , pp. 9-18
    • Bjorklund, A.1    Stenevi, U.2    Schmidt, R.H.3    Dunnett, S.B.4    Gage, F.H.5
  • 97
    • 0024392390 scopus 로고
    • Nigrostriatal reconstruction after 6-OHDA lesions in rats: Combination of dopamine-rich nigral grafts and nigrostriatal 'bridge' grafts
    • Dunnett SB, Rogers DC, Richards SJ. Nigrostriatal reconstruction after 6-OHDA lesions in rats: combination of dopamine-rich nigral grafts and nigrostriatal 'bridge' grafts. Exp Brain Res 1989;75:523-535.
    • (1989) Exp Brain Res , vol.75 , pp. 523-535
    • Dunnett, S.B.1    Rogers, D.C.2    Richards, S.J.3
  • 98
    • 0028360140 scopus 로고
    • Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model
    • Nikkhah G, Bentlage C, Cunningham MG, Bjorklund A. Intranigral fetal dopamine grafts induce behavioral compensation in the rat Parkinson model. J Neurosci 1994;14:3449-3461.
    • (1994) J Neurosci , vol.14 , pp. 3449-3461
    • Nikkhah, G.1    Bentlage, C.2    Cunningham, M.G.3    Bjorklund, A.4
  • 99
    • 0026458624 scopus 로고    scopus 로고
    • Widner H, Tetrud J, Rehncrona S, Snow B, Brundin P, Gustavii B, et al. Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). N Engl J Med 1992;327:1556-1563.
    • Widner H, Tetrud J, Rehncrona S, Snow B, Brundin P, Gustavii B, et al. Bilateral fetal mesencephalic grafting in two patients with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). N Engl J Med 1992;327:1556-1563.
  • 100
    • 20344368813 scopus 로고    scopus 로고
    • Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells
    • Yan Y, Yang D, Zarnowska ED, Du Z, Werbel B, Valliere C, et al. Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells 2005;23:781-790.
    • (2005) Stem Cells , vol.23 , pp. 781-790
    • Yan, Y.1    Yang, D.2    Zarnowska3    ED, D.Z.4    Werbel, B.5    Valliere, C.6
  • 102
    • 42149107420 scopus 로고    scopus 로고
    • Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells
    • Cho MS, Lee YE, Kim JY, Chung S, Cho YH, Kim DS, et al. Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells. Proc Natl Acad Sci USA 2008;105:3392-3397.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 3392-3397
    • Cho, M.S.1    Lee, Y.E.2    Kim, J.Y.3    Chung, S.4    Cho, Y.H.5    Kim, D.S.6
  • 103
    • 38349004470 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in Parkinsonian rats
    • Yang D, Zhang ZJ, Oldenburg M, Ayala M, Zhang SC. Human embryonic stem cell-derived dopaminergic neurons reverse functional deficit in Parkinsonian rats. Stem Cells 2008;26:55-63.
    • (2008) Stem Cells , vol.26 , pp. 55-63
    • Yang, D.1    Zhang, Z.J.2    Oldenburg, M.3    Ayala, M.4    Zhang, S.C.5
  • 104
    • 20244366112 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells over-expressing Bcl-2 promotes functional recovery after transient cerebral ischaemia
    • Wei L, Cui L, Snider BJ, Rivkin M, Yu SS, Lee CS, et al. Transplantation of embryonic stem cells over-expressing Bcl-2 promotes functional recovery after transient cerebral ischaemia. Neurobiol Dis 2005;19:183-193.
    • (2005) Neurobiol Dis , vol.19 , pp. 183-193
    • Wei, L.1    Cui, L.2    Snider, B.J.3    Rivkin, M.4    Yu, S.S.5    Lee, C.S.6
  • 105
    • 33845325474 scopus 로고    scopus 로고
    • Neuronal differentiation of transplanted embryonic stem cell-derived precursors in stroke lesions of adult rats
    • Buhnemann C, Scholz A, Bernreuther C, Malik CY, Braun H, Schachner M, et al. Neuronal differentiation of transplanted embryonic stem cell-derived precursors in stroke lesions of adult rats. Brain 2006;129:3238-3248.
    • (2006) Brain , vol.129 , pp. 3238-3248
    • Buhnemann, C.1    Scholz, A.2    Bernreuther, C.3    Malik, C.Y.4    Braun, H.5    Schachner, M.6
  • 106
    • 0037059050 scopus 로고    scopus 로고
    • Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat
    • Hoehn M, Kustermann E, Blunk J, Wiedermann D, Trapp T, Wecker S, et al. Monitoring of implanted stem cell migration in vivo: a highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat. Proc Natl Acad Sci USA 2002;99:16267-16272.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 16267-16272
    • Hoehn, M.1    Kustermann, E.2    Blunk, J.3    Wiedermann, D.4    Trapp, T.5    Wecker, S.6
  • 107
    • 22444449591 scopus 로고    scopus 로고
    • Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
    • Tabar V, Panagiotakos G, Greenberg ED, Chan BK, Sadelain M, Gutin PH, et al. Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nat Biotechnol 2005;23:601-606.
    • (2005) Nat Biotechnol , vol.23 , pp. 601-606
    • Tabar, V.1    Panagiotakos, G.2    Greenberg, E.D.3    Chan, B.K.4    Sadelain, M.5    Gutin, P.H.6
  • 108
    • 0036715222 scopus 로고    scopus 로고
    • Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage
    • Modo M, Stroemer RP, Tang E, Patel S, Hodges H. Effects of implantation site of stem cell grafts on behavioral recovery from stroke damage. Stroke 2002;33:2270-2278.
    • (2002) Stroke , vol.33 , pp. 2270-2278
    • Modo, M.1    Stroemer, R.P.2    Tang, E.3    Patel, S.4    Hodges, H.5
  • 109
  • 110
    • 0034705056 scopus 로고    scopus 로고
    • Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation
    • Liu S, Qu Y, Stewart TJ, Howard MJ, Chakrabortty S, Holekamp TF, et al. Embryonic stem cells differentiate into oligodendrocytes and myelinate in culture and after spinal cord transplantation. Proc Natl Acad Sci USA 2000;97:6126-6131.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 6126-6131
    • Liu, S.1    Qu, Y.2    Stewart, T.J.3    Howard, M.J.4    Chakrabortty, S.5    Holekamp, T.F.6
  • 111
    • 11244351576 scopus 로고    scopus 로고
    • Generation of purified oligodendrocyte progenitors from embryonic stem cells
    • Glaser T, Perez-Bouza A, Klein K, Brustle O. Generation of purified oligodendrocyte progenitors from embryonic stem cells. FASEB J 2005;19:112-114.
    • (2005) FASEB J , vol.19 , pp. 112-114
    • Glaser, T.1    Perez-Bouza, A.2    Klein, K.3    Brustle, O.4
  • 112
    • 13544264789 scopus 로고    scopus 로고
    • Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation
    • Nistor GI, Totoiu MO, Haque N, Carpenter MK, Keirstead HS. Human embryonic stem cells differentiate into oligodendrocytes in high purity and myelinate after spinal cord transplantation. Glia 2005;49:385-396.
    • (2005) Glia , vol.49 , pp. 385-396
    • Nistor, G.I.1    Totoiu, M.O.2    Haque, N.3    Carpenter, M.K.4    Keirstead, H.S.5
  • 113
    • 34547186776 scopus 로고    scopus 로고
    • Easy and rapid differentiation of embryonic stem cells into functional motor neurons using sonic hedgehog-producing cells
    • Soundararajan P, Lindsey BW, Leopold C, Rafuse VF. Easy and rapid differentiation of embryonic stem cells into functional motor neurons using sonic hedgehog-producing cells. Stem Cells 2007;25:1697-1706.
    • (2007) Stem Cells , vol.25 , pp. 1697-1706
    • Soundararajan, P.1    Lindsey, B.W.2    Leopold, C.3    Rafuse, V.F.4
  • 114
    • 34249694635 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived oligodendrocyte progenitors into rat spinal cord injuries does not cause harm
    • Cloutier F, Siegenthaler MM, Nistor G, Keirstead HS. Transplantation of human embryonic stem cell-derived oligodendrocyte progenitors into rat spinal cord injuries does not cause harm. Regen Med 2006;1:469-479.
    • (2006) Regen Med , vol.1 , pp. 469-479
    • Cloutier, F.1    Siegenthaler, M.M.2    Nistor, G.3    Keirstead, H.S.4
  • 115
    • 33644967927 scopus 로고    scopus 로고
    • Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: A long-term follow-up study
    • Bachoud-Levi AC, Gaura V, Brugieres P, Lefaucheur JP, Boisse MF, Maison P, et al. Effect of fetal neural transplants in patients with Huntington's disease 6 years after surgery: a long-term follow-up study. Lancet Neurol 2006;5:303-309.
    • (2006) Lancet Neurol , vol.5 , pp. 303-309
    • Bachoud-Levi, A.C.1    Gaura, V.2    Brugieres, P.3    Lefaucheur, J.P.4    Boisse, M.F.5    Maison, P.6
  • 116
  • 117
    • 34249694599 scopus 로고    scopus 로고
    • Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants
    • Li T, Steinbeck JA, Lusardi T, Koch P, Lan JQ, Wilz A, et al. Suppression of kindling epileptogenesis by adenosine releasing stem cell-derived brain implants. Brain 2007;130:1276-1288.
    • (2007) Brain , vol.130 , pp. 1276-1288
    • Li, T.1    Steinbeck, J.A.2    Lusardi, T.3    Koch, P.4    Lan, J.Q.5    Wilz, A.6
  • 118
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007;131:861-872.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5    Tomoda, K.6
  • 120
    • 38049028459 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
    • Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008;26:101-106.
    • (2008) Nat Biotechnol , vol.26 , pp. 101-106
    • Nakagawa, M.1    Koyanagi, M.2    Tanabe, K.3    Takahashi, K.4    Ichisaka, T.5    Aoi, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.