Mutant huntingtin alters MAPK signaling pathways in PC12 and striatal cells: ERK1/2 protects against mutant huntingtin-associated toxicity

Human Molecular Genetics

Volumn 15, Issue 2, 2006, Pages 273-285

  Apostol, Barbara L ^a   Illes, Katalin ^b   Pallos, Judit ^b   Bodai, Laszlo ^b   Wu, Jun ^c   Strand, Andrew ^d   Schweitzer, Erik S ^c   Olson, James M ^d   Kazantsev, Aleksey ^e   Marsh, J Lawrence ^b   Thompson, Leslie Michels ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CEP 11004; HUNTINGTIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MIXED LINEAGE KINASE; MUTANT PROTEIN; NEUROPROTECTIVE AGENT; POLYGLUTAMINE; PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN; CELL SURVIVAL; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; HUNTINGTON CHOREA; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; STRIATE CORTEX; UNINDEXED SEQUENCE;

ANIMALS; BLOTTING, NORTHERN; CELL LINE; CELL SURVIVAL; DNA PRIMERS; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; HUNTINGTON DISEASE; MICROARRAY ANALYSIS; MITOGEN-ACTIVATED PROTEIN KINASES; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; RATS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 31144472414     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi443     Document Type: Article

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