-
1
-
-
0030733023
-
FMR1 premutation allele (CGG)81 is stable in mice
-
Bontekoe C.J., de Graaff E., Nieuwenhuizen I.M., Willemsen R., and Oostra B.A. FMR1 premutation allele (CGG)81 is stable in mice. Eur. J. Hum. Genet. 5 (1997) 293-298
-
(1997)
Eur. J. Hum. Genet.
, vol.5
, pp. 293-298
-
-
Bontekoe, C.J.1
de Graaff, E.2
Nieuwenhuizen, I.M.3
Willemsen, R.4
Oostra, B.A.5
-
2
-
-
0035423079
-
Instability of a (CGG)98 repeat in the Fmr1 promoter
-
Bontekoe C.J., Bakker C.E., Nieuwenhuizen I.M., van der Linde H., Lans H., de Lange D., Hirst M.C., and Oostra B.A. Instability of a (CGG)98 repeat in the Fmr1 promoter. Hum. Mol. Genet. 10 (2001) 1693-1699
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 1693-1699
-
-
Bontekoe, C.J.1
Bakker, C.E.2
Nieuwenhuizen, I.M.3
van der Linde, H.4
Lans, H.5
de Lange, D.6
Hirst, M.C.7
Oostra, B.A.8
-
3
-
-
33846002696
-
Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation
-
Brouwer J.R., Mientjes E.J., Bakker C.E., Nieuwenhuizen I.M., Severijnen L.A., Van der Linde H.C., Nelson D.L., Oostra B.A., and Willemsen R. Elevated Fmr1 mRNA levels and reduced protein expression in a mouse model with an unmethylated Fragile X full mutation. Exp. Cell Res. 313 (2007) 244-253
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 244-253
-
-
Brouwer, J.R.1
Mientjes, E.J.2
Bakker, C.E.3
Nieuwenhuizen, I.M.4
Severijnen, L.A.5
Van der Linde, H.C.6
Nelson, D.L.7
Oostra, B.A.8
Willemsen, R.9
-
4
-
-
0032695779
-
Fully expanded FMR1 CGG repeats exhibit a length- and differentiation-dependent instability in cell hybrids that is independent of DNA methylation
-
Burman R.W., Popovich B.W., Jacky P.B., and Turker M.S. Fully expanded FMR1 CGG repeats exhibit a length- and differentiation-dependent instability in cell hybrids that is independent of DNA methylation. Hum. Mol. Genet. 8 (1999) 2293-2302
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 2293-2302
-
-
Burman, R.W.1
Popovich, B.W.2
Jacky, P.B.3
Turker, M.S.4
-
5
-
-
0032905253
-
Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells
-
Coffee B., Zhang F., Warren S.T., and Reines D. Acetylated histones are associated with FMR1 in normal but not fragile X-syndrome cells. Nat. Genet. 22 (1999) 98-101
-
(1999)
Nat. Genet.
, vol.22
, pp. 98-101
-
-
Coffee, B.1
Zhang, F.2
Warren, S.T.3
Reines, D.4
-
6
-
-
0036782129
-
Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome
-
Coffee B., Zhang F., Ceman S., Warren S.T., and Reines D. Histone modifications depict an aberrantly heterochromatinized FMR1 gene in fragile x syndrome. Am. J. Hum. Genet. 71 (2002) 923-932
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 923-932
-
-
Coffee, B.1
Zhang, F.2
Ceman, S.3
Warren, S.T.4
Reines, D.5
-
7
-
-
0035746538
-
FMR1 and the fragile X syndrome: human genome epidemiology review
-
Crawford D.C., Acuna J.M., and Sherman S.L. FMR1 and the fragile X syndrome: human genome epidemiology review. Genet. Med. 3 (2001) 359-371
-
(2001)
Genet. Med.
, vol.3
, pp. 359-371
-
-
Crawford, D.C.1
Acuna, J.M.2
Sherman, S.L.3
-
8
-
-
33645751438
-
Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features
-
Darr H., Mayshar Y., and Benvenisty N. Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features. Development 133 (2006) 1193-1201
-
(2006)
Development
, vol.133
, pp. 1193-1201
-
-
Darr, H.1
Mayshar, Y.2
Benvenisty, N.3
-
9
-
-
10944226097
-
Human embryonic stem cells as a model for early human development
-
Dvash T., and Benvenisty N. Human embryonic stem cells as a model for early human development. Best Pract. Res. Clin. Obstet. Gynaecol. 18 (2004) 929-940
-
(2004)
Best Pract. Res. Clin. Obstet. Gynaecol.
, vol.18
, pp. 929-940
-
-
Dvash, T.1
Benvenisty, N.2
-
10
-
-
19944386909
-
Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies
-
Dvash T., Mayshar Y., Darr H., McElhaney M., Barker D., Yanuka O., Kotkow K.J., Rubin L.L., Benvenisty N., and Eiges R. Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies. Hum. Reprod. 19 (2004) 2875-2883
-
(2004)
Hum. Reprod.
, vol.19
, pp. 2875-2883
-
-
Dvash, T.1
Mayshar, Y.2
Darr, H.3
McElhaney, M.4
Barker, D.5
Yanuka, O.6
Kotkow, K.J.7
Rubin, L.L.8
Benvenisty, N.9
Eiges, R.10
-
11
-
-
33748037728
-
Human embryonic stem cells as a powerful tool for studying human embryogenesis
-
Dvash T., Ben-Yosef D., and Eiges R. Human embryonic stem cells as a powerful tool for studying human embryogenesis. Pediatr. Res. 60 (2006) 111-117
-
(2006)
Pediatr. Res.
, vol.60
, pp. 111-117
-
-
Dvash, T.1
Ben-Yosef, D.2
Eiges, R.3
-
12
-
-
0030440796
-
Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus
-
Eberhart D.E., and Warren S.T. Nuclease sensitivity of permeabilized cells confirms altered chromatin formation at the fragile X locus. Somat. Cell Mol. Genet. 22 (1996) 435-441
-
(1996)
Somat. Cell Mol. Genet.
, vol.22
, pp. 435-441
-
-
Eberhart, D.E.1
Warren, S.T.2
-
13
-
-
0037010158
-
A molecular view on pluripotent stem cells
-
Eiges R., and Benvenisty N. A molecular view on pluripotent stem cells. FEBS Lett. 529 (2002) 135-141
-
(2002)
FEBS Lett.
, vol.529
, pp. 135-141
-
-
Eiges, R.1
Benvenisty, N.2
-
14
-
-
0035799309
-
Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells
-
Eiges R., Schuldiner M., Drukker M., Yanuka O., Itskovitz-Eldor J., and Benvenisty N. Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells. Curr. Biol. 11 (2001) 514-518
-
(2001)
Curr. Biol.
, vol.11
, pp. 514-518
-
-
Eiges, R.1
Schuldiner, M.2
Drukker, M.3
Yanuka, O.4
Itskovitz-Eldor, J.5
Benvenisty, N.6
-
15
-
-
33645132331
-
G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis
-
Feldman N., Gerson A., Fang J., Li E., Zhang Y., Shinkai Y., Cedar H., and Bergman Y. G9a-mediated irreversible epigenetic inactivation of Oct-3/4 during early embryogenesis. Nat. Cell Biol. 8 (2006) 188-194
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 188-194
-
-
Feldman, N.1
Gerson, A.2
Fang, J.3
Li, E.4
Zhang, Y.5
Shinkai, Y.6
Cedar, H.7
Bergman, Y.8
-
16
-
-
0028989063
-
Translational suppression by trinucleotide repeat expansion at FMR1
-
Feng Y., Zhang F., Lokey L.K., Chastain J.L., Lakkis L., Eberhart D., and Warren S.T. Translational suppression by trinucleotide repeat expansion at FMR1. Science 268 (1995) 731-734
-
(1995)
Science
, vol.268
, pp. 731-734
-
-
Feng, Y.1
Zhang, F.2
Lokey, L.K.3
Chastain, J.L.4
Lakkis, L.5
Eberhart, D.6
Warren, S.T.7
-
17
-
-
33845755946
-
Heterochromatin revisited
-
Grewal S.I., and Jia S. Heterochromatin revisited. Nat. Rev. Genet. 8 (2007) 35-46
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 35-46
-
-
Grewal, S.I.1
Jia, S.2
-
18
-
-
0034136393
-
Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers
-
Itskovitz-Eldor J., Schuldiner M., Karsenti D., Eden A., Yanuka O., Amit M., Soreq H., and Benvenisty N. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Mol. Med. 6 (2000) 88-95
-
(2000)
Mol. Med.
, vol.6
, pp. 88-95
-
-
Itskovitz-Eldor, J.1
Schuldiner, M.2
Karsenti, D.3
Eden, A.4
Yanuka, O.5
Amit, M.6
Soreq, H.7
Benvenisty, N.8
-
19
-
-
0030931869
-
Trinucleotide repeats (CGG)22TGG(CGG)43TGG(CGG)21 from the fragile X gene remain stable in transgenic mice
-
Lavedan C.N., Garrett L., and Nussbaum R.L. Trinucleotide repeats (CGG)22TGG(CGG)43TGG(CGG)21 from the fragile X gene remain stable in transgenic mice. Hum. Genet. 100 (1997) 407-414
-
(1997)
Hum. Genet.
, vol.100
, pp. 407-414
-
-
Lavedan, C.N.1
Garrett, L.2
Nussbaum, R.L.3
-
20
-
-
0032104278
-
Long uninterrupted CGG repeats within the first exon of the human FMR1 gene are not intrinsically unstable in transgenic mice
-
Lavedan C., Grabczyk E., Usdin K., and Nussbaum R.L. Long uninterrupted CGG repeats within the first exon of the human FMR1 gene are not intrinsically unstable in transgenic mice. Genomics 50 (1998) 229-240
-
(1998)
Genomics
, vol.50
, pp. 229-240
-
-
Lavedan, C.1
Grabczyk, E.2
Usdin, K.3
Nussbaum, R.L.4
-
21
-
-
0023657424
-
Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation
-
Lock L.F., Takagi N., and Martin G.R. Methylation of the Hprt gene on the inactive X occurs after chromosome inactivation. Cell 48 (1987) 39-46
-
(1987)
Cell
, vol.48
, pp. 39-46
-
-
Lock, L.F.1
Takagi, N.2
Martin, G.R.3
-
22
-
-
34247169864
-
Preimplantation genetic diagnosis (PGD) for fragile X syndrome using multiplex nested PCR of the FMR1 CGG-repeat region, the SRY gender marker and flanking polymorphic markers
-
Malcov M., Naiman T., Ben Yosef D., Carmon A., Mey-Raz N., Amit A., Vagman I., and Yaron Y. Preimplantation genetic diagnosis (PGD) for fragile X syndrome using multiplex nested PCR of the FMR1 CGG-repeat region, the SRY gender marker and flanking polymorphic markers. Reprod. Biomed. Online 14 (2007) 515-521
-
(2007)
Reprod. Biomed. Online
, vol.14
, pp. 515-521
-
-
Malcov, M.1
Naiman, T.2
Ben Yosef, D.3
Carmon, A.4
Mey-Raz, N.5
Amit, A.6
Vagman, I.7
Yaron, Y.8
-
23
-
-
19244362362
-
Familial transmission of the FMR1 CGG repeat
-
Nolin S.L., Lewis III F.A., Ye L.L., Houck Jr. G.E., Glicksman A.E., Limprasert P., Li S.Y., Zhong N., Ashley A.E., Feingold E., et al. Familial transmission of the FMR1 CGG repeat. Am. J. Hum. Genet. 59 (1996) 1252-1261
-
(1996)
Am. J. Hum. Genet.
, vol.59
, pp. 1252-1261
-
-
Nolin, S.L.1
Lewis III, F.A.2
Ye, L.L.3
Houck Jr., G.E.4
Glicksman, A.E.5
Limprasert, P.6
Li, S.Y.7
Zhong, N.8
Ashley, A.E.9
Feingold, E.10
-
24
-
-
0026339303
-
Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome
-
Oberle I., Rousseau F., Heitz D., Kretz C., Devys D., Hanauer A., Boue J., Bertheas M.F., and Mandel J.L. Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252 (1991) 1097-1102
-
(1991)
Science
, vol.252
, pp. 1097-1102
-
-
Oberle, I.1
Rousseau, F.2
Heitz, D.3
Kretz, C.4
Devys, D.5
Hanauer, A.6
Boue, J.7
Bertheas, M.F.8
Mandel, J.L.9
-
25
-
-
0036301947
-
A decade of molecular studies of fragile X syndrome
-
O'Donnell W.T., and Warren S.T. A decade of molecular studies of fragile X syndrome. Annu. Rev. Neurosci. 25 (2002) 315-338
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 315-338
-
-
O'Donnell, W.T.1
Warren, S.T.2
-
27
-
-
0036417439
-
Instability of a premutation-sized CGG repeat in FMR1 YAC transgenic mice
-
Peier A.M., and Nelson D.L. Instability of a premutation-sized CGG repeat in FMR1 YAC transgenic mice. Genomics 80 (2002) 423-432
-
(2002)
Genomics
, vol.80
, pp. 423-432
-
-
Peier, A.M.1
Nelson, D.L.2
-
28
-
-
14944386646
-
Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis
-
Pickering S.J., Minger S.L., Patel M., Taylor H., Black C., Burns C.J., Ekonomou A., and Braude P.R. Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis. Reprod. Biomed. Online 10 (2005) 390-397
-
(2005)
Reprod. Biomed. Online
, vol.10
, pp. 390-397
-
-
Pickering, S.J.1
Minger, S.L.2
Patel, M.3
Taylor, H.4
Black, C.5
Burns, C.J.6
Ekonomou, A.7
Braude, P.R.8
-
29
-
-
0037100616
-
Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine
-
Pietrobono R., Pomponi M.G., Tabolacci E., Oostra B., Chiurazzi P., and Neri G. Quantitative analysis of DNA demethylation and transcriptional reactivation of the FMR1 gene in fragile X cells treated with 5-azadeoxycytidine. Nucleic Acids Res. 30 (2002) 3278-3285
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3278-3285
-
-
Pietrobono, R.1
Pomponi, M.G.2
Tabolacci, E.3
Oostra, B.4
Chiurazzi, P.5
Neri, G.6
-
30
-
-
19944431036
-
Molecular dissection of the events leading to inactivation of the FMR1 gene
-
Pietrobono R., Tabolacci E., Zalfa F., Zito I., Terracciano A., Moscato U., Bagni C., Oostra B., Chiurazzi P., and Neri G. Molecular dissection of the events leading to inactivation of the FMR1 gene. Hum. Mol. Genet. 14 (2005) 267-277
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 267-277
-
-
Pietrobono, R.1
Tabolacci, E.2
Zalfa, F.3
Zito, I.4
Terracciano, A.5
Moscato, U.6
Bagni, C.7
Oostra, B.8
Chiurazzi, P.9
Neri, G.10
-
31
-
-
0034633526
-
Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells
-
Schuldiner M., Yanuka O., Itskovitz-Eldor J., Melton D.A., and Benvenisty N. Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci. USA 97 (2000) 11307-11312
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11307-11312
-
-
Schuldiner, M.1
Yanuka, O.2
Itskovitz-Eldor, J.3
Melton, D.A.4
Benvenisty, N.5
-
32
-
-
0028857169
-
Normal phenotype in two brothers with a full FMR1 mutation
-
Smeets H.J., Smits A.P., Verheij C.E., Theelen J.P., Willemsen R., van de Burgt I., Hoogeveen A.T., Oosterwijk J.C., and Oostra B.A. Normal phenotype in two brothers with a full FMR1 mutation. Hum. Mol. Genet. 4 (1995) 2103-2108
-
(1995)
Hum. Mol. Genet.
, vol.4
, pp. 2103-2108
-
-
Smeets, H.J.1
Smits, A.P.2
Verheij, C.E.3
Theelen, J.P.4
Willemsen, R.5
van de Burgt, I.6
Hoogeveen, A.T.7
Oosterwijk, J.C.8
Oostra, B.A.9
-
33
-
-
0026922707
-
DNA methylation represses FMR-1 transcription in fragile X syndrome
-
Sutcliffe J.S., Nelson D.L., Zhang F., Pieretti M., Caskey C.T., Saxe D., and Warren S.T. DNA methylation represses FMR-1 transcription in fragile X syndrome. Hum. Mol. Genet. 1 (1992) 397-400
-
(1992)
Hum. Mol. Genet.
, vol.1
, pp. 397-400
-
-
Sutcliffe, J.S.1
Nelson, D.L.2
Zhang, F.3
Pieretti, M.4
Caskey, C.T.5
Saxe, D.6
Warren, S.T.7
-
34
-
-
18844398832
-
Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments
-
Tabolacci E., Pietrobono R., Moscato U., Oostra B.A., Chiurazzi P., and Neri G. Differential epigenetic modifications in the FMR1 gene of the fragile X syndrome after reactivating pharmacological treatments. Eur. J. Hum. Genet. 13 (2005) 641-648
-
(2005)
Eur. J. Hum. Genet.
, vol.13
, pp. 641-648
-
-
Tabolacci, E.1
Pietrobono, R.2
Moscato, U.3
Oostra, B.A.4
Chiurazzi, P.5
Neri, G.6
-
35
-
-
0028246435
-
Fmr1 knockout mice: a model to study fragile X mental retardation
-
The Dutch-Belgian Fragile X Consortium
-
The Dutch-Belgian Fragile X Consortium. Fmr1 knockout mice: a model to study fragile X mental retardation. Cell 78 (1994) 23-33
-
(1994)
Cell
, vol.78
, pp. 23-33
-
-
-
36
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson J.A., Itskovitz-Eldor J., Shapiro S.S., Waknitz M.A., Swiergiel J.J., Marshall V.S., and Jones J.M. Embryonic stem cell lines derived from human blastocysts. Science 282 (1998) 1145-1147
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
37
-
-
3543030995
-
Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells
-
Urbach A., Schuldiner M., and Benvenisty N. Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells. Stem Cells 22 (2004) 635-641
-
(2004)
Stem Cells
, vol.22
, pp. 635-641
-
-
Urbach, A.1
Schuldiner, M.2
Benvenisty, N.3
-
38
-
-
0025905795
-
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome
-
Verkerk A.J., Pieretti M., Sutcliffe J.S., Fu Y.H., Kuhl D.P., Pizzuti A., Reiner O., Richards S., Victoria M.F., Zhang F.P., et al. Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in fragile X syndrome. Cell 65 (1991) 905-914
-
(1991)
Cell
, vol.65
, pp. 905-914
-
-
Verkerk, A.J.1
Pieretti, M.2
Sutcliffe, J.S.3
Fu, Y.H.4
Kuhl, D.P.5
Pizzuti, A.6
Reiner, O.7
Richards, S.8
Victoria, M.F.9
Zhang, F.P.10
-
39
-
-
11944264980
-
Human embryonic stem cell lines with genetic disorders
-
Verlinsky Y., Strelchenko N., Kukharenko V., Rechitsky S., Verlinsky O., Galat V., and Kuliev A. Human embryonic stem cell lines with genetic disorders. Reprod. Biomed. Online 10 (2005) 105-110
-
(2005)
Reprod. Biomed. Online
, vol.10
, pp. 105-110
-
-
Verlinsky, Y.1
Strelchenko, N.2
Kukharenko, V.3
Rechitsky, S.4
Verlinsky, O.5
Galat, V.6
Kuliev, A.7
-
40
-
-
0036626521
-
Timing of the absence of FMR1 expression in full mutation chorionic villi
-
Willemsen R., Bontekoe C.J., Severijnen L.A., and Oostra B.A. Timing of the absence of FMR1 expression in full mutation chorionic villi. Hum. Genet. 110 (2002) 601-605
-
(2002)
Hum. Genet.
, vol.110
, pp. 601-605
-
-
Willemsen, R.1
Bontekoe, C.J.2
Severijnen, L.A.3
Oostra, B.A.4
-
41
-
-
0034882704
-
Demethylation, reactivation, and destabilization of human fragile X full-mutation alleles in mouse embryocarcinoma cells
-
Wohrle D., Salat U., Hameister H., Vogel W., and Steinbach P. Demethylation, reactivation, and destabilization of human fragile X full-mutation alleles in mouse embryocarcinoma cells. Am. J. Hum. Genet. 69 (2001) 504-515
-
(2001)
Am. J. Hum. Genet.
, vol.69
, pp. 504-515
-
-
Wohrle, D.1
Salat, U.2
Hameister, H.3
Vogel, W.4
Steinbach, P.5
|