Human embryonic stem cells carrying mutations for severe genetic disorders

In Vitro Cellular and Developmental Biology - Animal

Volumn 46, Issue 3-4, 2010, Pages 327-336

  Frumkin, Tsvia ^a,c   Malcov, Mira ^a,c   Telias, Michael ^a,c   Gold, Veronica ^a,c   Schwartz, Tamar ^a,c   Azem, Foad ^a,c   Amit, Ami ^a,c   Yaron, Yuval ^b   Ben Yosef, Dalit ^a,c  

^a LIS MATERNITY HOSPITAL   (Israel)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Human embryonic stem cells; Preimplantation genetic diagnosis (PGD)

Indexed keywords

ARTICLE; BLASTOCYST; CELL DIFFERENTIATION; CELL LINE; CLONOGENIC ASSAY; CYTOLOGY; EMBRYONIC STEM CELL; GENE EXPRESSION REGULATION; GENETIC DISORDER; GENETICS; HUMAN; METABOLISM; METHODOLOGY; MUTATION; PLURIPOTENT STEM CELL; PRENATAL DIAGNOSIS; REPRODUCIBILITY;

BLASTOCYST; CELL DIFFERENTIATION; CELL LINE; COLONY-FORMING UNITS ASSAY; EMBRYONIC STEM CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC DISEASES, INBORN; HUMANS; MUTATION; PLURIPOTENT STEM CELLS; PREIMPLANTATION DIAGNOSIS; REPRODUCIBILITY OF RESULTS;

EID: 77952094754     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11626-010-9275-5     Document Type: Article

References (24)

1. D Ben-Yosef M Malcov R Eiges 2008 PGD-derived human embryonic stem cell lines as a powerful tool for the study of human genetic disorders Mol. Cell. Endocrinol. 282 153 158 10.1016/j.mce.2007.11.010 1:CAS:528:DC%2BD1cXitVegt7o%3D 18180094
2. JS Draper K Smith P Gokhale HD Moore E Maltby J Johnson L Meisner TP Zwaka JA Thomson PW Andrews 2004 Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells Nat. Biotechnol. 22 53 54 10.1038/nbt922 1:CAS:528:DC%2BD2cXls1eh 14661028 (Pubitemid 38057956)
3. T Dvash D Ben-Yosef R Eiges 2006 Human embryonic stem cells as a powerful tool for studying human embryogenesis Pediatr. Res. 60 111 117 10.1203/01.pdr.0000228349.24676.17 16864688 (Pubitemid 44297577)
4. T Dvash Y Mayshar H Darr M McElhaney D Barker O Yanuka KJ Kotkow LL Rubin N Benvenisty R Eiges 2004 Temporal gene expression during differentiation of human embryonic stem cells and embryoid bodies Hum. Reprod. 19 2875 2883 10.1093/humrep/deh529 1:CAS:528:DC%2BD2cXhtVSru7rO 15375076 (Pubitemid 40028961)
5. R Eiges M Schuldiner M Drukker O Yanuka J Itskovitz-Eldor N Benvenisty 2001 Establishment of human embryonic stem cell-transfected clones carrying a marker for undifferentiated cells Curr. Biol. 11 514 518 10.1016/S0960-9822(01) 00144-0 1:CAS:528:DC%2BD3MXjt1ajurk%3D 11413002 (Pubitemid 32305031)
6. R Eiges A Urbach M Malcov T Frumkin T Schwartz A Amit Y Yaron A Eden O Yanuka N Benvenisty D Ben-Yosef 2007 Developmental study of fragile X syndrome using human embryonic stem cells derived from preimplantation genetically diagnosed embryos Cell Stem Cell 1 568 577 10.1016/j.stem.2007.09.001 1:CAS:528:DC%2BD2sXhsVahtrjM 18371394 (Pubitemid 350079966)
7. N Findikli NZ Candan S Kahraman 2006 Human embryonic stem cell culture: current limitations and novel strategies Reprod. Biomed. Online 13 581 590 1:STN:280:DC%2BD28rnvFWquw%3D%3D 17007685
8. J Itskovitz-Eldor M Schuldiner D Karsenti A Eden O Yanuka M Amit H Soreq N Benvenisty 2000 Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers Mol. Med. 6 88 95 1:STN:280:DC%2BD3cvgt1WksA%3D%3D 10859025
9. K Keymolen V Goossens M De Rycke K Sermon K Boelaert M Bonduelle A Van Steirteghem I Liebaers 2007 Clinical outcome of preimplantation genetic diagnosis for cystic fibrosis: the Brussels' experience Eur. J. Hum. Genet. 15 752 758 10.1038/sj.ejhg.5201834 1:CAS:528:DC%2BD2sXmslSrtrY%3D 17440499 (Pubitemid 46965408)
10. HS Kim SK Oh YB Park HJ Ahn KC Sung MJ Kang LA Lee CS Suh SH Kim DW Kim SY Moon 2005 Methods for derivation of human embryonic stem cells Stem Cells 23 1228 1233 10.1634/stemcells.2004-0296 16051988 (Pubitemid 41504910)
11. N Lavon K Narwani T Golan-Lev N Buehler D Hill N Benvenisty 2008 Derivation of euploid human embryonic stem cells from aneuploid embryos Stem Cells 26 1874 1882 10.1634/stemcells.2008-0156 1:CAS:528:DC%2BD1cXpvV2lsrw%3D 18450823
12. M Malcov T Schwartz N Mei-Raz DB Yosef A Amit JB Lessing R Shomrat A Orr-Urtreger Y Yaron 2004 Multiplex nested PCR for preimplantation genetic diagnosis of spinal muscular atrophy Fetal. Diagn. Ther. 19 199 206 10.1159/000075151 14764971 (Pubitemid 38209783)
13. I Mateizel N De Temmerman U Ullmann G Cauffman K Sermon H Van de Velde M De Rycke E Degreef P Devroey I Liebaers A Van Steirteghem 2006 Derivation of human embryonic stem cell lines from embryos obtained after IVF and after PGD for monogenic disorders Hum. Reprod. 21 503 511 10.1093/humrep/dei345 1:STN:280:DC%2BD28%2FosVaksw%3D%3D 16284066 (Pubitemid 43159929)
14. TT Peura A Bosman T Stojanov 2007 Derivation of human embryonic stem cell lines Theriogenology 67 32 42 10.1016/j.theriogenology.2006.09.031 17074383 (Pubitemid 44854150)
15. SJ Pickering SL Minger M Patel H Taylor C Black CJ Burns A Ekonomou PR Braude 2005 Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis Reprod. Biomed. Online 10 390 397 15820050
16. BE Reubinoff MF Pera CY Fong A Trounson A Bongso 2000 Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro Nat. Biotechnol. 18 399 404 10.1038/74447 1:CAS:528:DC%2BD3cXis1Gmt74%3D 10748519 (Pubitemid 30217526)
17. M Schuldiner O Yanuka J Itskovitz-Eldor DA Melton N Benvenisty 2000 Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells Proc. Natl. Acad. Sci. U S A 97 11307 11312 10.1073/pnas.97.21.11307 1:CAS:528:DC%2BD3cXnsF2ruro%3D 11027332
18. Sullivan S.; Cowan C. A.; Eggan K. Human embryonic stem cells; the practical handbook. Wiley, West Sussex; 2007.
19. JA Thomson J Itskovitz-Eldor SS Shapiro MA Waknitz JJ Swiergiel VS Marshall JM Jones 1998 Embryonic stem cell lines derived from human blastocysts Science. 282 1145 1147 10.1126/science.282.5391.1145 1:CAS:528: DyaK1cXntleisLg%3D 9804556
20. A Trounson 2006 The production and directed differentiation of human embryonic stem cells Endocr. Rev. 27 208 219 10.1210/er.2005-0016 16434509
21. T Turetsky E Aizenman Y Gil N Weinberg Y Shufaro A Revel N Laufer A Simon D Abeliovich BE Reubinoff 2008 Laser-assisted derivation of human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis Hum. Reprod. 23 46 53 10.1093/humrep/dem351 1:CAS:528:DC%2BD2sXhsVWgsb3N 17989069 (Pubitemid 351767322)
22. A Urbach M Schuldiner N Benvenisty 2004 Modeling for Lesch-Nyhan disease by gene targeting in human embryonic stem cells Stem Cells 22 635 641 10.1634/stemcells.22-4-635 1:CAS:528:DC%2BD2cXntFGksLo%3D 15277709 (Pubitemid 39014579)
23. Y Verlinsky N Strelchenko V Kukharenko S Rechitsky O Verlinsky V Galat A Kuliev 2005 Human embryonic stem cell lines with genetic disorders Reprod. Biomed. Online 10 105 110 1:STN:280:DC%2BD2M%2FnslWntg%3D%3D 15705304
24. TP Zwaka JA Thomson 2003 Homologous recombination in human embryonic stem cells Nat. Biotechnol. 21 319 321 10.1038/nbt788 1:CAS:528:DC%2BD3sXhsFajs70%3D 12577066 (Pubitemid 36314818)