-
1
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J.T., Schols, L. and Riess, O. (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat. Genet., 18, 106-108.
-
(1998)
Nat. Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
2
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M.H., Lavedan, C., Leroy, E., Ide, S.E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R. et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
-
3
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz, J.J., Alegre, J., Gomez-Esteban, J.C., Lezcano, E., Ros, R., Ampuero, I., Vidal, L., Hoenicka, J., Rodriguez, O., Atares, B. et al (2004) The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann. Neurol., 55, 164-173.
-
(2004)
Ann. Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
-
4
-
-
4644236043
-
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease
-
Ibanez, P., Bonnet, A.M., Debarges, B., Lohmann, E., Tison, F., Pollak, P., Agid, Y., Durr, A. and Brice, A. (2004) Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. Lancet, 364, 1169-1171.
-
(2004)
Lancet
, vol.364
, pp. 1169-1171
-
-
Ibanez, P.1
Bonnet, A.M.2
Debarges, B.3
Lohmann, E.4
Tison, F.5
Pollak, P.6
Agid, Y.7
Durr, A.8
Brice, A.9
-
5
-
-
0242300619
-
alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton, A.B., Farrer, M., Johnson, J., Singleton, A., Hague, S., Kachergus, J., Hulihan, M., Peuralinna, T., Dutra, A., Nussbaum, R. et al. (2003) alpha-Synuclein locus triplication causes Parkinson's disease. Science, 302, 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
-
6
-
-
0032568534
-
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini, M.G., Crowther, R.A., Jakes, R., Hasegawa, M. and Goedert, M. (1998) alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc. Natl. Acad. Sci. USA, 95, 6469-6473.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
7
-
-
17544403675
-
Neural expression profile of alpha-synuclein in developing human cortex
-
Bayer, T.A., Jakala, P., Hartmann, T., Egensperger, R., Buslei, R., Falkai, P. and Beyreuther, K. (1999) Neural expression profile of alpha-synuclein in developing human cortex. Neuroreport, 10, 2799-2803.
-
(1999)
Neuroreport
, vol.10
, pp. 2799-2803
-
-
Bayer, T.A.1
Jakala, P.2
Hartmann, T.3
Egensperger, R.4
Buslei, R.5
Falkai, P.6
Beyreuther, K.7
-
8
-
-
0035069311
-
Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra
-
Galvin, J.E., Schuck, T.M., Lee, V.M. and Trojanowski, J.Q. (2001) Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra. Exp. Neurol., 168, 347-355.
-
(2001)
Exp. Neurol
, vol.168
, pp. 347-355
-
-
Galvin, J.E.1
Schuck, T.M.2
Lee, V.M.3
Trojanowski, J.Q.4
-
9
-
-
16644365520
-
-
Raghavan, R., Kruijff, L., Sterrenburg, M.D., Rogers, B.B., Hladik, C.L. and White, C.L., 3rd. (2004) Alpha-synuclein expression in the developing human brain. Pediatr. Dev. Pathol., 7, 506-516.
-
Raghavan, R., Kruijff, L., Sterrenburg, M.D., Rogers, B.B., Hladik, C.L. and White, C.L., 3rd. (2004) Alpha-synuclein expression in the developing human brain. Pediatr. Dev. Pathol., 7, 506-516.
-
-
-
-
10
-
-
0034077041
-
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
-
Abeliovich, A., Schmitz, Y., Farinas, I., Choi-Lundberg, D., Ho, W.H., Castillo, P.E., Shinsky, N., Verdugo, J.M., Armanini, M., Ryan, A. et al. (2000) Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system. Neuron, 25, 239-252.
-
(2000)
Neuron
, vol.25
, pp. 239-252
-
-
Abeliovich, A.1
Schmitz, Y.2
Farinas, I.3
Choi-Lundberg, D.4
Ho, W.H.5
Castillo, P.E.6
Shinsky, N.7
Verdugo, J.M.8
Armanini, M.9
Ryan, A.10
-
11
-
-
0345189364
-
Yeast cells provide insight into alpha-synuclein biology and pathobiology
-
Outeiro, T.F. and Lindquist, S. (2003) Yeast cells provide insight into alpha-synuclein biology and pathobiology. Science, 302, 1772-1775.
-
(2003)
Science
, vol.302
, pp. 1772-1775
-
-
Outeiro, T.F.1
Lindquist, S.2
-
12
-
-
0037971209
-
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein
-
Lakso, M., Vartiainen, S., Moilanen, A.M., Sirvio, J., Thomas, J.H., Nass, R., Blakely, R.D. and Wong, G. (2003) Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein. J. Neurochem., 86, 165-172.
-
(2003)
J. Neurochem
, vol.86
, pp. 165-172
-
-
Lakso, M.1
Vartiainen, S.2
Moilanen, A.M.3
Sirvio, J.4
Thomas, J.H.5
Nass, R.6
Blakely, R.D.7
Wong, G.8
-
13
-
-
0034704752
-
A Drosophila model of Parkinson's disease
-
Feany, M.B. and Bender, W.W. (2000) A Drosophila model of Parkinson's disease. Nature, 404, 394-398.
-
(2000)
Nature
, vol.404
, pp. 394-398
-
-
Feany, M.B.1
Bender, W.W.2
-
14
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson, B.I., Duda, J.E., Quinn, S.M., Zhang, B., Trojanowski, J.Q. and Lee, V.M. (2002) Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron, 34, 521-533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
15
-
-
0037173006
-
Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 -> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice
-
Lee, M.K., Stirling, W., Xu, Y., Xu, X., Qui, D., Mandir, A.S., Dawson, T.M., Copeland, N.G., Jenkins, N.A. and Price, D.L. (2002) Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 -> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice. Proc. Natl. Acad. Sci. USA, 99 8968-8973.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8968-8973
-
-
Lee, M.K.1
Stirling, W.2
Xu, Y.3
Xu, X.4
Qui, D.5
Mandir, A.S.6
Dawson, T.M.7
Copeland, N.G.8
Jenkins, N.A.9
Price, D.L.10
-
16
-
-
0034663176
-
Neuropathology in mice expressing human alpha-synuclein
-
van der Putten, H., Wiederhold, K.H., Probst, A., Barbieri, S., Mistl, C., Danner, S., Kauffmann, S., Hofele, K., Spooren, W.P., Ruegg, M.A. et al. (2000) Neuropathology in mice expressing human alpha-synuclein. J. Neurosci., 20, 6021-6029.
-
(2000)
J. Neurosci
, vol.20
, pp. 6021-6029
-
-
van der Putten, H.1
Wiederhold, K.H.2
Probst, A.3
Barbieri, S.4
Mistl, C.5
Danner, S.6
Kauffmann, S.7
Hofele, K.8
Spooren, W.P.9
Ruegg, M.A.10
-
17
-
-
0036550101
-
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system
-
Kirik, D., Rosenblad, C., Burger, C., Lundberg, C., Johansen, T.E., Muzyczka, N., Mandel, R.J. and Bjorklund, A. (2002) Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. J. Neurosci., 22, 2780-2791.
-
(2002)
J. Neurosci
, vol.22
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
Muzyczka, N.6
Mandel, R.J.7
Bjorklund, A.8
-
18
-
-
0036679197
-
alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
-
Lo Bianco, C., Ridet, J.L., Schneider, B.L., Deglon, N. and Aebischer, P. (2002) alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc. Natl. Acad. Sci. USA, 99, 10813-10818.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 10813-10818
-
-
Lo Bianco, C.1
Ridet, J.L.2
Schneider, B.L.3
Deglon, N.4
Aebischer, P.5
-
19
-
-
0345269757
-
Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of Parkinson's disease
-
Kirik, D., Annett, L.E., Burger, C., Muzyczka, N., Mandel, R.J. and Bjorklund, A. (2003) Nigrostriatal alpha-synucleinopathy induced by viral vector-mediated overexpression of human alpha-synuclein: A new primate model of Parkinson's disease. Proc. Natl. Acad. Sci. USA, 100, 2884-2889.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2884-2889
-
-
Kirik, D.1
Annett, L.E.2
Burger, C.3
Muzyczka, N.4
Mandel, R.J.5
Bjorklund, A.6
-
20
-
-
0742305862
-
Using human neural stem cells to model neurological disease
-
Jakel, R.J., Schneider, B.L. and Svendsen, C.N. (2004) Using human neural stem cells to model neurological disease. Nat. Rev. Genet., 5, 136-144.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 136-144
-
-
Jakel, R.J.1
Schneider, B.L.2
Svendsen, C.N.3
-
21
-
-
0032409396
-
A new method for the rapid and long term growth of human neural precursor cells
-
Svendsen, C.N., ter Borg, M.G., Armstrong, R.J., Rosser, A.E., Chandran, S., Ostenfeld, T. and Caldwell, M.A. (1998) A new method for the rapid and long term growth of human neural precursor cells. J. Neurosci. Methods, 85, 141-152.
-
(1998)
J. Neurosci. Methods
, vol.85
, pp. 141-152
-
-
Svendsen, C.N.1
ter Borg, M.G.2
Armstrong, R.J.3
Rosser, A.E.4
Chandran, S.5
Ostenfeld, T.6
Caldwell, M.A.7
-
22
-
-
33744903140
-
Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro
-
Wright, L.S., Prowse, K.R., Wallace, K., Linskens, M.H. and Svendsen, C.N. (2006) Human progenitor cells isolated from the developing cortex undergo decreased neurogenesis and eventual senescence following expansion in vitro. Exp. Cell Res., 312, 2107-2120.
-
(2006)
Exp. Cell Res
, vol.312
, pp. 2107-2120
-
-
Wright, L.S.1
Prowse, K.R.2
Wallace, K.3
Linskens, M.H.4
Svendsen, C.N.5
-
23
-
-
0032491416
-
Embryonic stem cell lines derived from human blastocysts
-
Thomson, J.A., Itskovitz-Eldor, J., Shapiro, S.S., Waknitz, M.A., Swiergiel, J.J., Marshall, V.S. and Jones, J.M. (1998) Embryonic stem cell lines derived from human blastocysts. Science, 282, 1145-1147.
-
(1998)
Science
, vol.282
, pp. 1145-1147
-
-
Thomson, J.A.1
Itskovitz-Eldor, J.2
Shapiro, S.S.3
Waknitz, M.A.4
Swiergiel, J.J.5
Marshall, V.S.6
Jones, J.M.7
-
24
-
-
13844271605
-
Specification of motoneurons from human embryonic stem cells
-
Li, X.J., Du, Z.W., Zarnowska, E.D., Pankratz, M., Hansen, L.O., Pearce, R.A. and Zhang, S.C. (2005) Specification of motoneurons from human embryonic stem cells. Nat. Biotechnol., 23, 215-221.
-
(2005)
Nat. Biotechnol
, vol.23
, pp. 215-221
-
-
Li, X.J.1
Du, Z.W.2
Zarnowska, E.D.3
Pankratz, M.4
Hansen, L.O.5
Pearce, R.A.6
Zhang, S.C.7
-
25
-
-
4344592974
-
Derivation of midbrain dopamine neurons from human embryonic stem cells
-
Perrier, A.L., Tabar, V., Barberi, T., Rubio, M.E., Bruses, J., Topf, N., Harrison, N.L. and Studer, L. (2004) Derivation of midbrain dopamine neurons from human embryonic stem cells. Proc. Natl. Acad. Sci. USA 101, 12543-12548.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 12543-12548
-
-
Perrier, A.L.1
Tabar, V.2
Barberi, T.3
Rubio, M.E.4
Bruses, J.5
Topf, N.6
Harrison, N.L.7
Studer, L.8
-
26
-
-
20344368813
-
Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells
-
Yan, Y., Yang, D., Zarnowska, E.D., Du, Z., Werbel, B., Valliere, C., Pearce, R.A., Thomson, J.A. and Zhang, S.C. (2005) Directed differentiation of dopaminergic neuronal subtypes from human embryonic stem cells. Stem Cells, 23, 781-790.
-
(2005)
Stem Cells
, vol.23
, pp. 781-790
-
-
Yan, Y.1
Yang, D.2
Zarnowska, E.D.3
Du, Z.4
Werbel, B.5
Valliere, C.6
Pearce, R.A.7
Thomson, J.A.8
Zhang, S.C.9
-
27
-
-
13844320376
-
Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations
-
Li, W., West, N., Colla, E., Pletnikova, O., Troncoso, J.C., Marsh, L., Dawson, T.M., Jakala, P., Hartmann, T., Price, D.L. et al. (2005) Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations. Proc. Natl. Acad. Sci. USA, 102, 2162-2167.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 2162-2167
-
-
Li, W.1
West, N.2
Colla, E.3
Pletnikova, O.4
Troncoso, J.C.5
Marsh, L.6
Dawson, T.M.7
Jakala, P.8
Hartmann, T.9
Price, D.L.10
-
28
-
-
33749570292
-
Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease
-
Anderson, J.P., Walker, D.E., Goldstein, J.M., de Laat, R., Banducci, K., Caccavello, R.J., Barbour, R., Huang, J., Kling, K., Lee, M. et al. (2006) Phosphorylation of Ser-129 is the dominant pathological modification of alpha-synuclein in familial and sporadic Lewy body disease. J. Biol. Chem., 281, 29739-29752.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 29739-29752
-
-
Anderson, J.P.1
Walker, D.E.2
Goldstein, J.M.3
de Laat, R.4
Banducci, K.5
Caccavello, R.J.6
Barbour, R.7
Huang, J.8
Kling, K.9
Lee, M.10
-
29
-
-
0037155197
-
Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein
-
Cole, N.B., Murphy, D.D., Grider, T., Rueter, S., Brasaemle, D. and Nussbaum, R.L. (2002) Lipid droplet binding and oligomerization properties of the Parkinson's disease protein alpha-synuclein. J. Biol. Chem., 277, 6344-6352.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 6344-6352
-
-
Cole, N.B.1
Murphy, D.D.2
Grider, T.3
Rueter, S.4
Brasaemle, D.5
Nussbaum, R.L.6
-
30
-
-
0032500599
-
Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation
-
Jensen, P.H., Nielsen, M.S., Jakes, R., Dotti, C.G. and Goedert, M. (1998) Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. J. Biol. Chem., 273, 26292-26294.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 26292-26294
-
-
Jensen, P.H.1
Nielsen, M.S.2
Jakes, R.3
Dotti, C.G.4
Goedert, M.5
-
31
-
-
0029874398
-
Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system
-
Svendsen, C.N., Clarke, D.J., Rosser, A.E. and Dunnett, S.B. (1996) Survival and differentiation of rat and human epidermal growth factor-responsive precursor cells following grafting into the lesioned adult central nervous system. Exp. Neurol., 137, 376-388.
-
(1996)
Exp. Neurol
, vol.137
, pp. 376-388
-
-
Svendsen, C.N.1
Clarke, D.J.2
Rosser, A.E.3
Dunnett, S.B.4
-
32
-
-
0037204598
-
Regional specification of rodent and human neurospheres
-
Ostenfeld, T., Joly, E., Tai, Y.T., Peters, A., Caldwell, M., Jauniaux, E. and Svendsen, C.N. (2002) Regional specification of rodent and human neurospheres. Brain Res. Dev. Brain Res., 134, 43-55.
-
(2002)
Brain Res. Dev. Brain Res
, vol.134
, pp. 43-55
-
-
Ostenfeld, T.1
Joly, E.2
Tai, Y.T.3
Peters, A.4
Caldwell, M.5
Jauniaux, E.6
Svendsen, C.N.7
-
33
-
-
0036278335
-
Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease
-
Xu, J., Kao, S.Y., Lee, F.J., Song, W., Jin, L.W. and Yankner, B.A. (2002) Dopamine-dependent neurotoxicity of alpha-synuclein: A mechanism for selective neurodegeneration in Parkinson disease. Nat. Med., 8, 600-606.
-
(2002)
Nat. Med
, vol.8
, pp. 600-606
-
-
Xu, J.1
Kao, S.Y.2
Lee, F.J.3
Song, W.4
Jin, L.W.5
Yankner, B.A.6
-
34
-
-
14944342522
-
The degeneration of dopamine neurons in Parkinson's disease: Insights from embryology and evolution of the mesostriatocortical system
-
Vernier, P., Moret, F., Callier, S., Snapyan, M., Wersinger, C. and Sidhu, A. (2004) The degeneration of dopamine neurons in Parkinson's disease: Insights from embryology and evolution of the mesostriatocortical system. Ann. N.Y. Acad. Sci., 1035, 231-249.
-
(2004)
Ann. N.Y. Acad. Sci
, vol.1035
, pp. 231-249
-
-
Vernier, P.1
Moret, F.2
Callier, S.3
Snapyan, M.4
Wersinger, C.5
Sidhu, A.6
-
35
-
-
1542613781
-
alpha-Synuclein A53T substitution associated with Parkinson disease also marks the divergence of Old World and New World primates
-
Hamilton, B.A. (2004) alpha-Synuclein A53T substitution associated with Parkinson disease also marks the divergence of Old World and New World primates. Genomics, 83, 739-742.
-
(2004)
Genomics
, vol.83
, pp. 739-742
-
-
Hamilton, B.A.1
-
36
-
-
0035109909
-
Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult
-
Lee, M., Hyun, D., Halliwell, B. and Jenner, P. (2001) Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult. J. Neurochem., 76, 998-1009.
-
(2001)
J. Neurochem
, vol.76
, pp. 998-1009
-
-
Lee, M.1
Hyun, D.2
Halliwell, B.3
Jenner, P.4
-
37
-
-
27544507306
-
Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration
-
Chandra, S., Gallardo, G., Fernandez-Chacon, R., Schluter, O.M. and Sudhof, T.C. (2005) Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration. Cell, 123, 383-396.
-
(2005)
Cell
, vol.123
, pp. 383-396
-
-
Chandra, S.1
Gallardo, G.2
Fernandez-Chacon, R.3
Schluter, O.M.4
Sudhof, T.C.5
-
38
-
-
0031866281
-
Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development
-
Hsu, L.J., Mallory, M., Xia, Y., Veinbergs, I., Hashimoto, M., Yoshimoto, M., Thal, L.J., Saitoh, T. and Masliah, E. (1998) Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development. J. Neurochem., 71, 338-344.
-
(1998)
J. Neurochem
, vol.71
, pp. 338-344
-
-
Hsu, L.J.1
Mallory, M.2
Xia, Y.3
Veinbergs, I.4
Hashimoto, M.5
Yoshimoto, M.6
Thal, L.J.7
Saitoh, T.8
Masliah, E.9
-
39
-
-
0032960760
-
Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex
-
Petersen, K., Olesen, O.F. and Mikkelsen, J.D. (1999) Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex. Neuroscience, 91, 651-659.
-
(1999)
Neuroscience
, vol.91
, pp. 651-659
-
-
Petersen, K.1
Olesen, O.F.2
Mikkelsen, J.D.3
-
40
-
-
0023722437
-
Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminal
-
Maroteaux, L., Campanelli, J.T. and Scheller, R.H. (1988) Synuclein: A neuron-specific protein localized to the nucleus and presynaptic nerve terminal. J. Neurosci., 8, 2804-2815.
-
(1988)
J. Neurosci
, vol.8
, pp. 2804-2815
-
-
Maroteaux, L.1
Campanelli, J.T.2
Scheller, R.H.3
-
41
-
-
0038456964
-
Nuclear localization of alpha-synuclein and its interaction with histones
-
Goers, J., Manning-Bog, A.B., McCormack, A.L., Millett, I.S., Doniach, S., Di Monte, D.A., Uversky, V.N. and Fink, A.L. (2003) Nuclear localization of alpha-synuclein and its interaction with histones. Biochemistry, 42, 8465-8471.
-
(2003)
Biochemistry
, vol.42
, pp. 8465-8471
-
-
Goers, J.1
Manning-Bog, A.B.2
McCormack, A.L.3
Millett, I.S.4
Doniach, S.5
Di Monte, D.A.6
Uversky, V.N.7
Fink, A.L.8
-
42
-
-
33746338256
-
Linker Histone H1 Binds to Disease Associated Amyloid-like Fibrils
-
Duce, J.A., Smith, D.P., Blake, R.E., Crouch, P.J., Li, Q.X., Masters, C.L. and Trounce, I.A. (2006) Linker Histone H1 Binds to Disease Associated Amyloid-like Fibrils. J. Mol. Biol., 361, 493-505.
-
(2006)
J. Mol. Biol
, vol.361
, pp. 493-505
-
-
Duce, J.A.1
Smith, D.P.2
Blake, R.E.3
Crouch, P.J.4
Li, Q.X.5
Masters, C.L.6
Trounce, I.A.7
-
43
-
-
33744790040
-
Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein
-
Vartiainen, S., Pehkonen, P., Lakso, M., Nass, R. and Wong, G. (2006) Identification of gene expression changes in transgenic C. elegans overexpressing human alpha-synuclein. Neurobiol. Dis., 22, 477-486.
-
(2006)
Neurobiol. Dis
, vol.22
, pp. 477-486
-
-
Vartiainen, S.1
Pehkonen, P.2
Lakso, M.3
Nass, R.4
Wong, G.5
-
44
-
-
33749583553
-
-
alpha}-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity
-
Kontopoulos, E., Parvin, J.D. and Feany, M.B. (2006) {alpha}-synuclein acts in the nucleus to inhibit histone acetylation and promote neurotoxicity. Hum. Mol. Genet., 15, 3012-3023.
-
(2006)
Hum. Mol. Genet
, vol.15
, pp. 3012-3023
-
-
Kontopoulos, E.1
Parvin, J.D.2
Feany, M.B.3
-
45
-
-
33751118534
-
Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
-
Chu, Y. and Kordower, J.H. (2006) Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease? Neurobiol. Dis., 25, 134-149.
-
(2006)
Neurobiol. Dis
, vol.25
, pp. 134-149
-
-
Chu, Y.1
Kordower, J.H.2
-
46
-
-
0033669319
-
In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies
-
Gai, W.P., Yuan, H.X., Li, X.Q., Power, J.T., Blumbergs, P.C. and Jensen, P.H. (2000) In situ and in vitro study of colocalization and segregation of alpha-synuclein, ubiquitin, and lipids in Lewy bodies. Exp. Neurol., 166, 324-333.
-
(2000)
Exp. Neurol
, vol.166
, pp. 324-333
-
-
Gai, W.P.1
Yuan, H.X.2
Li, X.Q.3
Power, J.T.4
Blumbergs, P.C.5
Jensen, P.H.6
-
47
-
-
0038673084
-
Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex
-
Viti, J., Feathers, A., Phillips, J. and Lillien, L. (2003) Epidermal growth factor receptors control competence to interpret leukemia inhibitory factor as an astrocyte inducer in developing cortex. J. Neurosci., 23, 3385-3393.
-
(2003)
J. Neurosci
, vol.23
, pp. 3385-3393
-
-
Viti, J.1
Feathers, A.2
Phillips, J.3
Lillien, L.4
-
48
-
-
20944442861
-
A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis
-
He, F., Ge, W., Martinowich, K., Becker-Catania, S., Coskun, V., Zhu, W., Wu, H., Castro, D., Guillemot, F., Fan, G. et al. (2005) A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis. Nat. Neurosci., 8, 616-625.
-
(2005)
Nat. Neurosci
, vol.8
, pp. 616-625
-
-
He, F.1
Ge, W.2
Martinowich, K.3
Becker-Catania, S.4
Coskun, V.5
Zhu, W.6
Wu, H.7
Castro, D.8
Guillemot, F.9
Fan, G.10
-
49
-
-
32544442518
-
Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology
-
Braak, H., de Vos, R.A., Bohl, J. and Del Tredici, K. (2006) Gastric alpha-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology. Neurosci. Lett., 396, 67-72.
-
(2006)
Neurosci. Lett
, vol.396
, pp. 67-72
-
-
Braak, H.1
de Vos, R.A.2
Bohl, J.3
Del Tredici, K.4
-
50
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak, H., Del Tredici, K., Rub, U., de Vos, R.A., Jansen Steur, E.N. and Braak, E. (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol. Aging, 24, 197-211.
-
(2003)
Neurobiol. Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
Braak, E.6
-
51
-
-
0037019332
-
Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
-
Kim, J.H., Auerbach, J.M., Rodriguez-Gomez, J.A., Velasco, I., Gavin, D., Lumelsky, N., Lee, S.H., Nguyen, J., Sanchez-Pernaute, R., Bankiewicz, K. et al. (2002) Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature, 418, 50-56.
-
(2002)
Nature
, vol.418
, pp. 50-56
-
-
Kim, J.H.1
Auerbach, J.M.2
Rodriguez-Gomez, J.A.3
Velasco, I.4
Gavin, D.5
Lumelsky, N.6
Lee, S.H.7
Nguyen, J.8
Sanchez-Pernaute, R.9
Bankiewicz, K.10
-
52
-
-
31044445499
-
Identification of intrinsic determinants of midbrain dopamine neurons
-
Andersson, E., Tryggvason, U., Deng, Q., Friling, S., Alekseenko, Z., Robert, B., Perlmann, T. and Ericson, J. (2006) Identification of intrinsic determinants of midbrain dopamine neurons. Cell, 124 393-405.
-
(2006)
Cell
, vol.124
, pp. 393-405
-
-
Andersson, E.1
Tryggvason, U.2
Deng, Q.3
Friling, S.4
Alekseenko, Z.5
Robert, B.6
Perlmann, T.7
Ericson, J.8
-
53
-
-
33745063639
-
Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death
-
Yamashita, H., Nakamura, T., Takahashi, T., Nagano, Y., Hiji, M., Hirabayashi, T., Amano, T., Yagi, T., Sakai, N., Kohriyama, T. et al. (2006) Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death. J. Neurochem., 98, 45-56.
-
(2006)
J. Neurochem
, vol.98
, pp. 45-56
-
-
Yamashita, H.1
Nakamura, T.2
Takahashi, T.3
Nagano, Y.4
Hiji, M.5
Hirabayashi, T.6
Amano, T.7
Yagi, T.8
Sakai, N.9
Kohriyama, T.10
-
54
-
-
0032577445
-
FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
-
Ye, W., Shimamura, K., Rubenstein, J.L., Hynes, M.A. and Rosenthal, A. (1998) FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate. Cell, 93, 755-766.
-
(1998)
Cell
, vol.93
, pp. 755-766
-
-
Ye, W.1
Shimamura, K.2
Rubenstein, J.L.3
Hynes, M.A.4
Rosenthal, A.5
-
55
-
-
0036468957
-
Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture
-
Zhou, W., Schaack, J., Zawada, W.M. and Freed, C.R. (2002) Overexpression of human alpha-synuclein causes dopamine neuron death in primary human mesencephalic culture. Brain Res., 926, 42-50.
-
(2002)
Brain Res
, vol.926
, pp. 42-50
-
-
Zhou, W.1
Schaack, J.2
Zawada, W.M.3
Freed, C.R.4
-
56
-
-
0038701729
-
Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines
-
Baptista, M.J., O'Farrell, C., Daya, S., Ahmad, R., Miller, D.W., Hardy, J., Farrer, M.J. and Cookson, M.R. (2003) Co-ordinate transcriptional regulation of dopamine synthesis genes by alpha-synuclein in human neuroblastoma cell lines. J. Neurochem., 85, 957-968.
-
(2003)
J. Neurochem
, vol.85
, pp. 957-968
-
-
Baptista, M.J.1
O'Farrell, C.2
Daya, S.3
Ahmad, R.4
Miller, D.W.5
Hardy, J.6
Farrer, M.J.7
Cookson, M.R.8
-
57
-
-
0035957754
-
Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
-
Wakayama, T., Tabar, V., Rodriguez, I., Perry, A.C., Studer, L. and Mombaerts, P. (2001) Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science, 292, 740-743.
-
(2001)
Science
, vol.292
, pp. 740-743
-
-
Wakayama, T.1
Tabar, V.2
Rodriguez, I.3
Perry, A.C.4
Studer, L.5
Mombaerts, P.6
-
58
-
-
4544319823
-
Lentiviral-mediated gene transfer to model triplet repeat disorders
-
Regulier, E., Zala, D., Aebischer, P. and Deglon, N. (2004) Lentiviral-mediated gene transfer to model triplet repeat disorders. Methods Mol. Biol., 277, 199-213.
-
(2004)
Methods Mol. Biol
, vol.277
, pp. 199-213
-
-
Regulier, E.1
Zala, D.2
Aebischer, P.3
Deglon, N.4
-
59
-
-
0037431266
-
Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression
-
Lizee, G., Aerts, J.L., Gonzales, M.I., Chinnasamy, N., Morgan, R.A. and Topalian, S.L. (2003) Real-time quantitative reverse transcriptase-polymerase chain reaction as a method for determining lentiviral vector titers and measuring transgene expression. Hum. Gene Ther., 14, 497-507.
-
(2003)
Hum. Gene Ther
, vol.14
, pp. 497-507
-
-
Lizee, G.1
Aerts, J.L.2
Gonzales, M.I.3
Chinnasamy, N.4
Morgan, R.A.5
Topalian, S.L.6
|