-
1
-
-
0038662595
-
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors
-
Pin JP, Galvez T, Prezeau L 2003 Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptors. Pharmacol Ther 98:325-354
-
(2003)
Pharmacol Ther
, vol.98
, pp. 325-354
-
-
Pin, J.P.1
Galvez, T.2
Prezeau, L.3
-
2
-
-
0033600911
-
Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca2+ receptor critical for dimerization. Implications for function of monomeric Ca2+ receptor
-
Ray K, Hauschild BC, Steinbach PJ, Goldsmith PK, Hauache O, Spiegel AM 1999 Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca2+ receptor critical for dimerization. Implications for function of monomeric Ca2+ receptor. J Biol Chem 274:27642-27650
-
(1999)
J Biol Chem
, vol.274
, pp. 27642-27650
-
-
Ray, K.1
Hauschild, B.C.2
Steinbach, P.J.3
Goldsmith, P.K.4
Hauache, O.5
Spiegel, A.M.6
-
3
-
-
0035895907
-
The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions
-
Zhang Z, Sun S, Quinn SJ, Brown EM, Bai M 2001 The extracellular calcium-sensing receptor dimerizes through multiple types of intermolecular interactions. J Biol Chem 276:5316-5322
-
(2001)
J Biol Chem
, vol.276
, pp. 5316-5322
-
-
Zhang, Z.1
Sun, S.2
Quinn, S.J.3
Brown, E.M.4
Bai, M.5
-
4
-
-
1842689987
-
Modulation of interprotomer relationships is important for activation of dimeric calcium-sensing receptor
-
Jiang Y, Minet E, Zhang Z, Silver PA, Bai M 2004 Modulation of interprotomer relationships is important for activation of dimeric calcium-sensing receptor. J Biol Chem 279:14147-14156
-
(2004)
J Biol Chem
, vol.279
, pp. 14147-14156
-
-
Jiang, Y.1
Minet, E.2
Zhang, Z.3
Silver, P.A.4
Bai, M.5
-
5
-
-
33748291578
-
Biophysical properties of the extracellular domain of the calcium-sensing receptor
-
Ryan ZC, Craig TA, Venyaminov SY, Thompson JR, Kumar R 2006 Biophysical properties of the extracellular domain of the calcium-sensing receptor. Biochem Biophys Res Commun 349:339344
-
(2006)
Biochem Biophys Res Commun
, vol.349
, pp. 339344
-
-
Ryan, Z.C.1
Craig, T.A.2
Venyaminov, S.Y.3
Thompson, J.R.4
Kumar, R.5
-
6
-
-
0032917158
-
Domains determining ligand specificity for Ca2+ receptors
-
Hammerland LG, Krapcho KJ, Garrett JE, Alasti N, Hung BC, Simin RT, Levinthal C, Nemeth EF, Fuller FH 1999 Domains determining ligand specificity for Ca2+ receptors. Mol Pharmacol 55:642-648
-
(1999)
Mol Pharmacol
, vol.55
, pp. 642-648
-
-
Hammerland, L.G.1
Krapcho, K.J.2
Garrett, J.E.3
Alasti, N.4
Hung, B.C.5
Simin, R.T.6
Levinthal, C.7
Nemeth, E.F.8
Fuller, F.H.9
-
7
-
-
0037650260
-
The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain
-
Brauner-Osborne H, Jensen AA, Sheppard PO, O'Hara P, Krogs-gaard-Larsen P 1999 The agonist-binding domain of the calcium-sensing receptor is located at the amino-terminal domain. J Biol Chem 274:18382-18386
-
(1999)
J Biol Chem
, vol.274
, pp. 18382-18386
-
-
Brauner-Osborne, H.1
Jensen, A.A.2
Sheppard, P.O.3
O'Hara, P.4
Krogs-gaard-Larsen, P.5
-
8
-
-
34547131843
-
Identification and dissection of Ca2+-binding sites in the extracellular domain of Ca2+-sensing receptor
-
Huang Y, Zhou Y, Yang W, Butters R, Lee HW, Li S, Castiblanco A, Brown EM, Yang JJ 2007 Identification and dissection of Ca2+-binding sites in the extracellular domain of Ca2+-sensing receptor. J Biol Chem 282:19000-19010
-
(2007)
J Biol Chem
, vol.282
, pp. 19000-19010
-
-
Huang, Y.1
Zhou, Y.2
Yang, W.3
Butters, R.4
Lee, H.W.5
Li, S.6
Castiblanco, A.7
Brown, E.M.8
Yang, J.J.9
-
9
-
-
27844587815
-
Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor
-
Silve C, Petrel C, Leroy C, Bruel H, Mallet E, Rognan D, Ruat M 2005 Delineating a Ca2+ binding pocket within the venus flytrap module of the human calcium-sensing receptor. J Biol Chem 280: 37917-37923
-
(2005)
J Biol Chem
, vol.280
, pp. 37917-37923
-
-
Silve, C.1
Petrel, C.2
Leroy, C.3
Bruel, H.4
Mallet, E.5
Rognan, D.6
Ruat, M.7
-
10
-
-
20344362178
-
Amino acid recognition by venus flytrap domains is encoded in an 8-residue motif
-
Acher FC, Bertrand HO 2005 Amino acid recognition by venus flytrap domains is encoded in an 8-residue motif. Biopolymers 80: 357-366
-
(2005)
Biopolymers
, vol.80
, pp. 357-366
-
-
Acher, F.C.1
Bertrand, H.O.2
-
11
-
-
23844491861
-
A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing
-
Mun HC, Culverston EL, Franks AH, Collyer CA, Clifton-Bligh RJ, Conigrave AD 2005 A double mutation in the extracellular Ca2+-sensing receptor's venus flytrap domain that selectively disables L-amino acid sensing. J Biol Chem 280:29067-29072
-
(2005)
J Biol Chem
, vol.280
, pp. 29067-29072
-
-
Mun, H.C.1
Culverston, E.L.2
Franks, A.H.3
Collyer, C.A.4
Clifton-Bligh, R.J.5
Conigrave, A.D.6
-
12
-
-
80053057994
-
Interdomain movements in metabotropic glutamate receptor activation
-
Huang S, CaoJ, Jiang M, Labesse G, LiuJ, PinJP, Rondard P2011 Interdomain movements in metabotropic glutamate receptor activation. Proc Natl Acad Sci USA 108:15480-15485
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 15480-15485
-
-
Huang, S.1
Cao, J.2
Jiang, M.3
Labesse, G.4
Liu, J.5
Pin, J.P.6
Rondard, P.7
-
13
-
-
0034716854
-
Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors
-
Hu J, Hauache O, Spiegel AM 2000 Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors. J Biol Chem 275:16382-16389
-
(2000)
J Biol Chem
, vol.275
, pp. 16382-16389
-
-
Hu, J.1
Hauache, O.2
Spiegel, A.M.3
-
14
-
-
35948951986
-
Molecular genetic analysis of the calcium sensing receptor gene in patients clinically suspected to have familial hypocalciuric hypercalcemia: Phenotypic variation and mutation spectrum in a Danish population
-
Nissen PH, Christensen SE, Heickendorff L, Brixen K, Mosekilde L 2007 Molecular genetic analysis of the calcium sensing receptor gene in patients clinically suspected to have familial hypocalciuric hypercalcemia: phenotypic variation and mutation spectrum in a Danish population. J Clin Endocrinol Metab 92:4373-4379
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 4373-4379
-
-
Nissen, P.H.1
Christensen, S.E.2
Heickendorff, L.3
Brixen, K.4
Mosekilde, L.5
-
15
-
-
57349098264
-
Novel inactivating mutations of the calcium-sensing receptor: The calcimimetic NPS R-568 improves signal transduction of mutant receptors
-
Rus R, Haag C, Bumke-Vogt C, Bahr V, Mayr B, Mohlig M, Schulze E, Frank-Raue K, Raue F, Schofl C 2008 Novel inactivating mutations of the calcium-sensing receptor: the calcimimetic NPS R-568 improves signal transduction of mutant receptors. J Clin Endocrinol Metab 93:4797-4803
-
(2008)
J Clin Endocrinol Metab
, vol.93
, pp. 4797-4803
-
-
Rus, R.1
Haag, C.2
Bumke-Vogt, C.3
Bahr, V.4
Mayr, B.5
Mohlig, M.6
Schulze, E.7
Frank-Raue, K.8
Raue, F.9
Schofl, C.10
-
16
-
-
0029897495
-
Constitutively active mutants of the a1B-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation
-
Scheer A, Fanelli F, Costa T, De Benedetti PG, Cotecchia S 1996 Constitutively active mutants of the a1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation. EMBO J 15:3566-3578
-
(1996)
EMBO J
, vol.15
, pp. 3566-3578
-
-
Scheer, A.1
Fanelli, F.2
Costa, T.3
de Benedetti, P.G.4
Cotecchia, S.5
-
17
-
-
33947381686
-
The highly conserved DRY motif of class A G protein-coupled receptors: Beyond the ground state
-
Rovati GE, Capra V, Neubig RR 2007 The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol Pharmacol 71:959-964
-
(2007)
Mol Pharmacol
, vol.71
, pp. 959-964
-
-
Rovati, G.E.1
Capra, V.2
Neubig, R.R.3
-
18
-
-
37349060671
-
Complementary roles of the DRY motif and C-terminus tail of GPCRs for G protein coupling and β-arrestin interaction
-
Kim KM, Caron MG 2008 Complementary roles of the DRY motif and C-terminus tail of GPCRs for G protein coupling and β-arrestin interaction. Biochem Biophys Res Commun 366:42-47
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 42-47
-
-
Kim, K.M.1
Caron, M.G.2
-
19
-
-
0037166287
-
Evidence for distinct cation and calcimi-metic compound (NPS 568) recognition domains in the transmembrane regions of the human Ca2+ receptor
-
Ray K, Northup JK 2002 Evidence for distinct cation and calcimi-metic compound (NPS 568) recognition domains in the transmembrane regions of the human Ca2+ receptor. J Biol Chem 277: 18908-18913
-
(2002)
J Biol Chem
, vol.277
, pp. 18908-18913
-
-
Ray, K.1
Northup, J.K.2
-
20
-
-
0033679325
-
Effects of a calcimimetic compound and naturally activating mutation on the human Ca2+ receptor and on Ca2+ receptor/metabo-tropic glutamate chimeric receptors
-
Hauache OM, Hu J, Ray K, Xie R, Jacobson KA, Spiegel AM 2000 Effects of a calcimimetic compound and naturally activating mutation on the human Ca2+ receptor and on Ca2+ receptor/metabo-tropic glutamate chimeric receptors. Endocrinology 141:41564163
-
(2000)
Endocrinology
, vol.141
, pp. 41564163
-
-
Hauache, O.M.1
Hu, J.2
Ray, K.3
Xie, R.4
Jacobson, K.A.5
Spiegel, A.M.6
-
21
-
-
1342346546
-
Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site
-
Miedlich SU, Gama L, Seuwen K, Wolf RM, Breitwieser GE 2004 Homology modeling of the transmembrane domain of the human calcium sensing receptor and localization of an allosteric binding site. J Biol Chem 279:7254-7263
-
(2004)
J Biol Chem
, vol.279
, pp. 7254-7263
-
-
Miedlich, S.U.1
Gama, L.2
Seuwen, K.3
Wolf, R.M.4
Breitwieser, G.E.5
-
22
-
-
2442548717
-
Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain
-
Petrel C, Kessler A, Dauban P, Dodd RH, Rognan D, Ruat M 2004 Positive and negative allosteric modulators of the Ca2+-sensing receptor interact within overlapping but not identical binding sites in the transmembrane domain. J Biol Chem 279:18990-18997
-
(2004)
J Biol Chem
, vol.279
, pp. 18990-18997
-
-
Petrel, C.1
Kessler, A.2
Dauban, P.3
Dodd, R.H.4
Rognan, D.5
Ruat, M.6
-
24
-
-
0030612562
-
The Ca2+-sensing receptor (CaR) activates phospholipases C, A2, and D in bovine parathyroid and CaR-transfected human embryonic kidney (HEK293) cells
-
Kifor O, Diaz R, Butters R, Brown EM 1997 The Ca2+-sensing receptor (CaR) activates phospholipases C, A2, and D in bovine parathyroid and CaR-transfected human embryonic kidney (HEK293) cells. J Bone Miner Res 12:715-725
-
(1997)
J Bone Miner Res
, vol.12
, pp. 715-725
-
-
Kifor, O.1
Diaz, R.2
Butters, R.3
Brown, E.M.4
-
25
-
-
0037036446
-
Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor
-
Huang C, Handlogten ME, Miller RT 2002 Parallel activation of phosphatidylinositol 4-kinase and phospholipase C by the extracellular calcium-sensing receptor. J Biol Chem 277:20293-20300
-
(2002)
J Biol Chem
, vol.277
, pp. 20293-20300
-
-
Huang, C.1
Handlogten, M.E.2
Miller, R.T.3
-
26
-
-
0032510839
-
Co-expression of a Ca2+-inhibitable adenylyl cyclase and of a Ca2+-sensing receptor in the cortical thick ascending limb cell of the rat kidney. Inhibition of hormone-dependent cAMP accumulation by extracellular Ca2+
-
deJesus Ferreira MC, Helies-Toussaint C, Imbert-TeboulM, Bailly C, Verbavatz JM, Bellanger AC, Chabardes D 1998 Co-expression of a Ca2+-inhibitable adenylyl cyclase and of a Ca2+-sensing receptor in the cortical thick ascending limb cell of the rat kidney. Inhibition of hormone-dependent cAMP accumulation by extracellular Ca2+. J Biol Chem 273:15192-15202
-
(1998)
J Biol Chem
, vol.273
, pp. 15192-15202
-
-
deJesus Ferreira, M.C.1
Helies-Toussaint, C.2
Imbert-Teboul, M.3
Bailly, C.4
Verbavatz, J.M.5
Bellanger, A.C.6
Chabardes, D.7
-
27
-
-
27544486835
-
Termination of cAMP signals by Ca2+ and Gai via extracellular Ca2+ sensors: A link to intracellular Ca2+ oscillations
-
Gerbino A, Ruder WC, Curci S, Pozzan T, Zaccolo M, Hofer AM 2005 Termination of cAMP signals by Ca2+ and Gai via extracellular Ca2+ sensors: a link to intracellular Ca2+ oscillations. J Cell Biol 171:303-312
-
(2005)
J Cell Biol
, vol.171
, pp. 303-312
-
-
Gerbino, A.1
Ruder, W.C.2
Curci, S.3
Pozzan, T.4
Zaccolo, M.5
Hofer, A.M.6
-
28
-
-
0037469737
-
Activation of the MAP kinase cascade by exogenous calcium-sensing receptor
-
Hobson SA, Wright J, Lee F, McNeil SE, Bilderback T, Rodland KD 2003 Activation of the MAP kinase cascade by exogenous calcium-sensing receptor. Mol Cell Endocrinol 200:189-198
-
(2003)
Mol Cell Endocrinol
, vol.200
, pp. 189-198
-
-
Hobson, S.A.1
Wright, J.2
Lee, F.3
McNeil, S.E.4
Bilderback, T.5
Rodland, K.D.6
-
29
-
-
4344565323
-
Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in pros tate cancer cells: Role of epidermal growth factor receptor transactivation
-
Yano S, Macleod RJ, Chattopadhyay N, Tfelt-Hansen J, Kifor O, Butters RR, Brown EM 2004 Calcium-sensing receptor activation stimulates parathyroid hormone-related protein secretion in pros tate cancer cells: role of epidermal growth factor receptor transactivation. Bone 35:664-672
-
(2004)
Bone
, vol.35
, pp. 664-672
-
-
Yano, S.1
Macleod, R.J.2
Chattopadhyay, N.3
Tfelt-Hansen, J.4
Kifor, O.5
Butters, R.R.6
Brown, E.M.7
-
30
-
-
33744800246
-
Ca2+-sensing receptor induces Rho kinase-mediated actin stress fiber assembly and altered cell morphology, but not in response to aromatic amino acids
-
Davies SL, Gibbons CE, Vizard T, Ward DT 2006 Ca2+-sensing receptor induces Rho kinase-mediated actin stress fiber assembly and altered cell morphology, but not in response to aromatic amino acids. Am J Physiol Cell Physiol 290:C1543-C1551
-
(2006)
Am J Physiol Cell Physiol
, vol.290
-
-
Davies, S.L.1
Gibbons, C.E.2
Vizard, T.3
Ward, D.T.4
-
31
-
-
70349786422
-
Activation of choline kinase by extracellular Ca2+ is Ca2+-sensing receptor, Ga12 and Rho-dependent in breast cancer cells
-
Huang C, Hydo LM, Liu S, Miller RT 2009 Activation of choline kinase by extracellular Ca2+ is Ca2+-sensing receptor, Ga12 and Rho-dependent in breast cancer cells. Cell Signal 21:1894-1900
-
(2009)
Cell Signal
, vol.21
, pp. 1894-1900
-
-
Huang, C.1
Hydo, L.M.2
Liu, S.3
Miller, R.T.4
-
32
-
-
54049137686
-
Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells
-
Mamillapalli R, VanHouten J, Zawalich W, Wysolmerski J 2008 Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. J Biol Chem 283:2443524447
-
(2008)
J Biol Chem
, vol.283
, pp. 2443524447
-
-
Mamillapalli, R.1
VanHouten, J.2
Zawalich, W.3
Wysolmerski, J.4
-
33
-
-
76649136659
-
The calcium-sensing receptor couples to Ga (s) and regulates PTHrP and ACTH secretion in pituitary cells
-
Mamillapalli R, Wysolmerski J 2010 The calcium-sensing receptor couples to Ga (s) and regulates PTHrP and ACTH secretion in pituitary cells. J Endocrinol 204:287-297
-
(2010)
J Endocrinol
, vol.204
, pp. 287-297
-
-
Mamillapalli, R.1
Wysolmerski, J.2
-
34
-
-
79951606631
-
The calcium-sensing receptor: A molecular perspective
-
Magno AL, Ward BK, Ratajczak T 2011 The calcium-sensing receptor: a molecular perspective. Endocr Rev 32:3-30
-
(2011)
Endocr Rev
, vol.32
, pp. 3-30
-
-
Magno, A.L.1
Ward, B.K.2
Ratajczak, T.3
-
35
-
-
65949090315
-
Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor
-
Brennan SC, Conigrave AD 2009 Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor. Curr Pharm Biotechnol 10:270-281
-
(2009)
Curr Pharm Biotechnol
, vol.10
, pp. 270-281
-
-
Brennan, S.C.1
Conigrave, A.D.2
-
36
-
-
0021960391
-
Regulation of parathyroid hormone release and cytosolic calcium by extracellular calcium in dispersed and cultured bovine and pathological human parathyroid cells
-
LeBoff MS, Shoback D, Brown EM, Thatcher J, Leombruno R, Beaudoin D, Henry M, Wilson R, Pallotta J, Marynick S, Stock J, Leight G 1985 Regulation of parathyroid hormone release and cytosolic calcium by extracellular calcium in dispersed and cultured bovine and pathological human parathyroid cells. J Clin Invest 75:49-57
-
(1985)
J Clin Invest
, vol.75
, pp. 49-57
-
-
LeBoff, M.S.1
Shoback, D.2
Brown, E.M.3
Thatcher, J.4
Leombruno, R.5
Beaudoin, D.6
Henry, M.7
Wilson, R.8
Pallotta, J.9
Marynick, S.10
Stock, J.11
Leight, G.12
-
37
-
-
0020675794
-
Four-parameter model of sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue
-
Brown EM 1983 Four-parameter model of sigmoidal relationship between parathyroid hormone release and extracellular calcium concentration in normal and abnormal parathyroid tissue. J Clin Endocrinol Metab 56:572-581
-
(1983)
J Clin Endocrinol Metab
, vol.56
, pp. 572-581
-
-
Brown, E.M.1
-
38
-
-
0345171002
-
Disorders of calcium homeostasis
-
Carmeliet G, Van Cromphaut S, Daci E, Maes C, Bouillon R 2003 Disorders of calcium homeostasis. Best Pract Res Clin Endocrinol Metab 17:529-546
-
(2003)
Best Pract Res Clin Endocrinol Metab
, vol.17
, pp. 529-546
-
-
Carmeliet, G.1
van Cromphaut, S.2
Daci, E.3
Maes, C.4
Bouillon, R.5
-
39
-
-
33748966446
-
Role of calcium-sensing receptor in mineral ion metabolism and inherited disorders of calcium-sensing
-
Chattopadhyay N, Brown EM 2006 Role of calcium-sensing receptor in mineral ion metabolism and inherited disorders of calcium-sensing. Mol Genet Metab 89:189-202
-
(2006)
Mol Genet Metab
, vol.89
, pp. 189-202
-
-
Chattopadhyay, N.1
Brown, E.M.2
-
40
-
-
79551670370
-
The regulation of parathyroid hormone secretion and synthesis
-
Kumar R, Thompson JR 2011 The regulation of parathyroid hormone secretion and synthesis. J Am Soc Nephrol 22:216-224
-
(2011)
J Am Soc Nephrol
, vol.22
, pp. 216-224
-
-
Kumar, R.1
Thompson, J.R.2
-
41
-
-
0034947319
-
Human parathyroid cell proliferation in response to calcium, NPS R-467, calcitriol and phosphate
-
Roussanne MC, Lieberherr M, Souberbielle JC, Sarfati E, Drueke T, Bourdeau A 2001 Human parathyroid cell proliferation in response to calcium, NPS R-467, calcitriol and phosphate. Eur J Clin Invest 31:610-616
-
(2001)
Eur J Clin Invest
, vol.31
, pp. 610-616
-
-
Roussanne, M.C.1
Lieberherr, M.2
Souberbielle, J.C.3
Sarfati, E.4
Drueke, T.5
Bourdeau, A.6
-
42
-
-
0036095974
-
Mitogen-activated protein kinase cascade in human normal and tumoral parathyroid cells
-
Corbetta S, Lania A, Filopanti M, Vicentini L, Ballare E, Spada A 2002 Mitogen-activated protein kinase cascade in human normal and tumoral parathyroid cells. J Clin Endocrinol Metab 87:22012205
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 22012205
-
-
Corbetta, S.1
Lania, A.2
Filopanti, M.3
Vicentini, L.4
Ballare, E.5
Spada, A.6
-
43
-
-
0034023688
-
Calcium-sensing receptor expression and signaling in human parathyroid adenomas and primary hyperplasia
-
Corbetta S, Mantovani G, Lania A, Borgato S, Vicentini L, Beretta E, Faglia G, Di Blasio AM, Spada A 2000 Calcium-sensing receptor expression and signaling in human parathyroid adenomas and primary hyperplasia. Clin Endocrinol 52:339-348
-
(2000)
Clin Endocrinol
, vol.52
, pp. 339-348
-
-
Corbetta, S.1
Mantovani, G.2
Lania, A.3
Borgato, S.4
Vicentini, L.5
Beretta, E.6
Faglia, G.7
Di Blasio, A.M.8
Spada, A.9
-
44
-
-
79955748231
-
Regulator of G protein signaling 5 is highly expressed in parathyroid tunors and inhibits signaling by the calcium-sensing receptor
-
Koh J, Dar M, Untch BR, Dixit D, Shi Y, Yang Z, Adam MA, Dressman H, Wang X, Gesty-Palmer D, Marks JR, Spurney R, Druey KM, Olson Jr JA 2011 Regulator of G protein signaling 5 is highly expressed in parathyroid tunors and inhibits signaling by the calcium-sensing receptor. Mol Endocrinol 25:867-876
-
(2011)
Mol Endocrinol
, vol.25
, pp. 867-876
-
-
Koh, J.1
Dar, M.2
Untch, B.R.3
Dixit, D.4
Shi, Y.5
Yang, Z.6
Adam, M.A.7
Dressman, H.8
Wang, X.9
Gesty-Palmer, D.10
Marks, J.R.11
Spurney, R.12
Druey, K.M.13
Olson Jr, J.A.14
-
45
-
-
2442689139
-
Role of the calcium-sensing receptor in parathyroid gland physiology
-
Chen RA, Goodman WG 2004 Role of the calcium-sensing receptor in parathyroid gland physiology. AM J Physiol Renal Physiol 286: F1005-F1011
-
(2004)
AM J Physiol Renal Physiol
, vol.286
-
-
Chen, R.A.1
Goodman, W.G.2
-
46
-
-
27744578945
-
Calcium-sensing receptor expression and parathyroid hormone secretion in hyperplastic parathyroid glands from humans
-
Canadillas S, Canalejo A, Santamaria R, Rodriguez ME, EstepaJC, Martin-Malo A, Bravo J, Ramos B, Aguilera-Tejero E, Rodriguez M, Almaden Y 2005 Calcium-sensing receptor expression and parathyroid hormone secretion in hyperplastic parathyroid glands from humans. J Am Soc Nephrol 16:2190-2197
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2190-2197
-
-
Canadillas, S.1
Canalejo, A.2
Santamaria, R.3
Rodriguez, M.E.4
Estepa, J.C.5
Martin-Malo, A.6
Bravo, J.7
Ramos, B.8
Aguilera-Tejero, E.9
Rodriguez, M.10
Almaden, Y.11
-
47
-
-
65949123580
-
The role of the calcium-sensing receptor in bone biology and pathophysiology
-
Theman TA, Collins MT 2009 The role of the calcium-sensing receptor in bone biology and pathophysiology. Curr Pharm Bio-technol 10:289-301
-
(2009)
Curr Pharm Bio-technol
, vol.10
, pp. 289-301
-
-
Theman, T.A.1
Collins, M.T.2
-
49
-
-
0346363825
-
In vitro studies with the calcimimetic, cinacalcet HCl, on normal human adult osteoblastic and osteoclastic cells
-
Shalhoub V, Grisanti M, Padagas J, Scully S, Rattan A, Qi M, Varnum B, Vezina C, Lacey D, Martin D 2003 In vitro studies with the calcimimetic, cinacalcet HCl, on normal human adult osteoblastic and osteoclastic cells. Crit Rev Eukaryot Gene Expr 13:89106
-
(2003)
Crit Rev Eukaryot Gene Expr
, vol.13
, pp. 89106
-
-
Shalhoub, V.1
Grisanti, M.2
Padagas, J.3
Scully, S.4
Rattan, A.5
Qi, M.6
Varnum, B.7
Vezina, C.8
Lacey, D.9
Martin, D.10
-
50
-
-
2942519523
-
Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G protein-coupled receptor
-
Wellendorph P, Brauner-Osborne H 2004 Molecular cloning, expression, and sequence analysis of GPRC6A, a novel family C G protein-coupled receptor. Gene 335:37-46
-
(2004)
Gene
, vol.335
, pp. 37-46
-
-
Wellendorph, P.1
Brauner-Osborne, H.2
-
51
-
-
14944341203
-
Deorphanization of GPRC6A: A promiscuous L-a-amino acid receptor with preference for basic amino acids
-
Wellendorph P, Hansen KB, Balsgaard A, GreenwoodJR, Egebjerg J, Brauner-Osborne H 2005 Deorphanization of GPRC6A: a promiscuous L-a-amino acid receptor with preference for basic amino acids. Mol Pharmacol 67:589-597
-
(2005)
Mol Pharmacol
, vol.67
, pp. 589-597
-
-
Wellendorph, P.1
Hansen, K.B.2
Balsgaard, A.3
Greenwood, J.R.4
Egebjerg, J.5
Brauner-Osborne, H.6
-
52
-
-
77953508447
-
Impaired osteoblast function in GPRC6A null mice
-
Pi M, Zhang L, Lei SF, Huang MZ, Zhu W, ZhangJ, Shen H, Deng HW, Quarles LD 2010 Impaired osteoblast function in GPRC6A null mice. J Bone Miner Res 25:1092-1102
-
(2010)
J Bone Miner Res
, vol.25
, pp. 1092-1102
-
-
Pi, M.1
Zhang, L.2
Lei, S.F.3
Huang, M.Z.4
Zhu, W.5
Zhang, J.6
Shen, H.7
Deng, H.W.8
Quarles, L.D.9
-
53
-
-
78049317365
-
Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion
-
Feng J, Petersen CD, Coy DH, Jiang JK, Thomas CJ, Pollak MR, Wank SA 2010 Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion. Proc Natl Acad Sci USA 107:17791-17796
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 17791-17796
-
-
Feng, J.1
Petersen, C.D.2
Coy, D.H.3
Jiang, J.K.4
Thomas, C.J.5
Pollak, M.R.6
Wank, S.A.7
-
54
-
-
67651184136
-
The functions and roles of the extracellular Ca2+-sensing receptor along the gastrointestinal tract
-
Geibel JP, Hebert SC 2009 The functions and roles of the extracellular Ca2+-sensing receptor along the gastrointestinal tract. Annu Rev Physiol 71:205-217
-
(2009)
Annu Rev Physiol
, vol.71
, pp. 205-217
-
-
Geibel, J.P.1
Hebert, S.C.2
-
55
-
-
77956510723
-
Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition
-
Rey O, Young SH, Jacamo R, Moyer MP, Rozengurt E 2010 Extracellular calcium sensing receptor stimulation in human colonic epithelial cells induces intracellular calcium oscillations and proliferation inhibition. J Cell Physiol 225:73-83
-
(2010)
J Cell Physiol
, vol.225
, pp. 73-83
-
-
Rey, O.1
Young, S.H.2
Jacamo, R.3
Moyer, M.P.4
Rozengurt, E.5
-
56
-
-
84855502399
-
Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium
-
Rey O, Chang W, Bikle D, Rozengurt N, Young SH, Rozengurt E 2012 Negative cross-talk between calcium-sensing receptor and β-catenin signaling systems in colonic epithelium. J Biol Chem287: 1158-1167
-
(2012)
J Biol Chem
, vol.287
, pp. 1158-1167
-
-
Rey, O.1
Chang, W.2
Bikle, D.3
Rozengurt, N.4
Young, S.H.5
Rozengurt, E.6
-
57
-
-
77649147285
-
Physiology and pathophysiology of the calcium-sensing receptor in the kidney
-
Riccardi D, Brown EM 2010 Physiology and pathophysiology of the calcium-sensing receptor in the kidney. Am J Physiol Renal Physiol 298:F485-F499
-
(2010)
Am J Physiol Renal Physiol
, vol.298
-
-
Riccardi, D.1
Brown, E.M.2
-
58
-
-
33745367478
-
Expression of PTHrP, PTH/PTHrP receptor, and Ca2+-sensing mRNAs along the rat nephron
-
Yang T, Hassan S, Huang YG, Smart AM, Briggs JP, Schnermann JB 1997 Expression of PTHrP, PTH/PTHrP receptor, and Ca2+-sensing mRNAs along the rat nephron. Am J Physiol 272:F751-F758
-
(1997)
Am J Physiol
, vol.272
-
-
Yang, T.1
Hassan, S.2
Huang, Y.G.3
Smart, A.M.4
Briggs, J.P.5
Schnermann, J.B.6
-
59
-
-
0029859514
-
Localization of the extracellular Ca2+-sensing receptor and PTH/ PTHrP receptor in rat kidney
-
Riccardi D, Lee WS, Lee K, Segre GV, Brown EM, Hebert SC 1996 Localization of the extracellular Ca2+-sensing receptor and PTH/ PTHrP receptor in rat kidney. Am J Physiol 271:F951-F956
-
(1996)
Am J Physiol
, vol.271
-
-
Riccardi, D.1
Lee, W.S.2
Lee, K.3
Segre, G.V.4
Brown, E.M.5
Hebert, S.C.6
-
60
-
-
0032014951
-
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in the rat kidney
-
Riccardi D, Hall AE, Chattopadhyay N, Xu JZ, Brown EM, Hebert SC 1998 Localization of the extracellular Ca2+/polyvalent cation-sensing protein in the rat kidney. Am J Physiol 274:F611-F622
-
(1998)
Am J Physiol
, vol.274
-
-
Riccardi, D.1
Hall, A.E.2
Chattopadhyay, N.3
Xu, J.Z.4
Brown, E.M.5
Hebert, S.C.6
-
61
-
-
0242665678
-
Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport
-
Ba J, Brown D, Friedman PA 2003 Calcium-sensing receptor regulation of PTH-inhibitable proximal tubule phosphate transport. Am J Physiol Renal Physiol 285:F1233-F1243
-
(2003)
Am J Physiol Renal Physiol
, vol.285
-
-
Ba, J.1
Brown, D.2
Friedman, P.A.3
-
62
-
-
64149091308
-
Thick ascending limb: The Na+:K+: 2Cl_ cotransporter, NKCC2, and the calcium-sensing receptor, CaSR
-
Gamba G, Friedman PA 2009 Thick ascending limb: the Na+:K+: 2Cl_ cotransporter, NKCC2, and the calcium-sensing receptor, CaSR. Pflugers Arch 458:61-76
-
(2009)
Pflugers Arch
, vol.458
, pp. 61-76
-
-
Gamba, G.1
Friedman, P.A.2
-
63
-
-
62549137372
-
Activation of the Ca2+-sensing receptor stimulates the activity of the epithelial Ca2+ channel TRPV5
-
Topala CN, Schoeber JP, Searchfield LE, Riccardi D, Hoenderop JG, Bindels RJ 2009 Activation of the Ca2+-sensing receptor stimulates the activity of the epithelial Ca2+ channel TRPV5. Cell Calcium 45:331-339
-
(2009)
Cell Calcium
, vol.45
, pp. 331-339
-
-
Topala, C.N.1
Schoeber, J.P.2
Searchfield, L.E.3
Riccardi, D.4
Hoenderop, J.G.5
Bindels, R.J.6
-
64
-
-
21644471863
-
Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells
-
Procino G, Carmosino M, Tamma G, Gouraud S, Laera A, Riccardi D, Svelto M, Valenti G 2004 Extracellular calcium antagonizes forskolin-induced aquaporin 2 trafficking in collecting duct cells. Kidney Int 66:2245-2255
-
(2004)
Kidney Int
, vol.66
, pp. 2245-2255
-
-
Procino, G.1
Carmosino, M.2
Tamma, G.3
Gouraud, S.4
Laera, A.5
Riccardi, D.6
Svelto, M.7
Valenti, G.8
-
65
-
-
0030944936
-
Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medulary collecting duct
-
Sands JM, Naruse M, Baum M, Jo I, Hebert SC, Brown EM, Harris HW 1997 Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medulary collecting duct. J Clin Invest99:1399-1405
-
(1997)
J Clin Invest
, vol.99
, pp. 1399-1405
-
-
Sands, J.M.1
Naruse, M.2
Baum, M.3
Jo, I.4
Hebert, S.C.5
Brown, E.M.6
Harris, H.W.7
-
66
-
-
68049128243
-
The calcium-sensing receptor promotes urinary acidification to prevent nephrolithiasis
-
1705-1513
-
Renkema KY, Velic A, Dijkman HB, Verkaart S, van der Kemp AW, Nowik M, Timmermans K, Doucet A, Wagner CA, Bindels RJ, Hoenderop JG 2009 The calcium-sensing receptor promotes urinary acidification to prevent nephrolithiasis. J AM Soc Nephrol 20:1705-1513
-
(2009)
J AM Soc Nephrol
, vol.20
-
-
Renkema, K.Y.1
Velic, A.2
Dijkman, H.B.3
Verkaart, S.4
van der Kemp, A.W.5
Nowik, M.6
Timmermans, K.7
Doucet, A.8
Wagner, C.A.9
Bindels, R.J.10
Hoenderop, J.G.11
-
67
-
-
0030944936
-
Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct
-
Sands JM, Naruse M, Baum M, Jo I, Hebert SC, Brown EM, Harris HW 1997 Apical extracellular calcium/polyvalent cation-sensing receptor regulates vasopressin-elicited water permeability in rat kidney inner medullary collecting duct. J Clin Invest 99:1399-1405
-
(1997)
J Clin Invest
, vol.99
, pp. 1399-1405
-
-
Sands, J.M.1
Naruse, M.2
Baum, M.3
Jo, I.4
Hebert, S.C.5
Brown, E.M.6
Harris, H.W.7
-
68
-
-
73849089953
-
Novel Ca receptor signaling pathways for control of renal ion transport
-
Huang C, Miller RT 2010 Novel Ca receptor signaling pathways for control of renal ion transport. Curr Opin Nephrol Hypertens 19:106-112
-
(2010)
Curr Opin Nephrol Hypertens
, vol.19
, pp. 106-112
-
-
Huang, C.1
Miller, R.T.2
-
69
-
-
38849145209
-
The calcium-sensing receptor: Physiology, pathophysiology and CaR-based therapeutics
-
Brown EM 2007 The calcium-sensing receptor: physiology, pathophysiology and CaR-based therapeutics. Subcell Biochem 45:139167
-
(2007)
Subcell Biochem
, vol.45
, pp. 139167
-
-
Brown, E.M.1
-
71
-
-
80855144843
-
Activating mutations in the calcium-sensing receptor: Genetic and clinical spectrum in 25 patients with autosomal dominant hypocalcaemia-a German survey
-
Raue F, Pichl J, Dorr HG, Schnabel D, Heidemann P, Hammersen G, Jaursch-Hancke C, Santen R, Schofl C, Wabitsch M, Haag C, Schulze E, Frank-Raue K 2011 Activating mutations in the calcium-sensing receptor: genetic and clinical spectrum in 25 patients with autosomal dominant hypocalcaemia-a German survey. Clin Endocrinol 75:760-765
-
(2011)
Clin Endocrinol
, vol.75
, pp. 760-765
-
-
Raue, F.1
Pichl, J.2
Dorr, H.G.3
Schnabel, D.4
Heidemann, P.5
Hammersen, G.6
Jaursch-Hancke, C.7
Santen, R.8
Schofl, C.9
Wabitsch, M.10
Haag, C.11
Schulze, E.12
Frank-Raue, K.13
-
73
-
-
34249718528
-
Structure and function of the human calcium-sensing receptor: Insights from natural and engineered mutations and allosteric modulators
-
Hu J, Spiegel AM 2007 Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators. J Bone Miner Res 22:601-608
-
(2007)
J Bone Miner Res
, vol.22
, pp. 601-608
-
-
Hu, J.1
Spiegel, A.M.2
-
74
-
-
0042233567
-
Naturally occurring mutations of the extracellular Ca2+-sensing receptor: Implications for its structure and function
-
Hu J, Spiegel AM 2003 Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function. Trends Endocrinol Metab 14:282-288
-
(2003)
Trends Endocrinol Metab
, vol.14
, pp. 282-288
-
-
Hu, J.1
Spiegel, A.M.2
-
75
-
-
3442886787
-
CASRdb: Calcium-sensing receptor locus-specific database for mutations causing familial (benign) hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia
-
Pidasheva S, D'Souza-Li L, Canaff L, Cole DE, Hendy GN 2004 CASRdb: calcium-sensing receptor locus-specific database for mutations causing familial (benign) hypocalciuric hypercalcemia, neonatal severe hyperparathyroidism, and autosomal dominant hypocalcemia. Hum Mutat 24:107-111
-
(2004)
Hum Mutat
, vol.24
, pp. 107-111
-
-
Pidasheva, S.1
D'Souza-Li, L.2
Canaff, L.3
Cole, D.E.4
Hendy, G.N.5
-
76
-
-
0028260585
-
Familial benign hypercalcemia-from clinical description to molecular genetics
-
Heath 3rd H 1994 Familial benign hypercalcemia-from clinical description to molecular genetics. West J Med 160:554-561
-
(1994)
West J Med
, vol.160
, pp. 554-561
-
-
Heath III, H.1
-
77
-
-
33846429183
-
Clinical lessons from the calcium-sensing receptor
-
Brown EM 2007 Clinical lessons from the calcium-sensing receptor. Nat Clin Pract Endocrinol Metab 3:122-133
-
(2007)
Nat Clin Pract Endocrinol Metab
, vol.3
, pp. 122-133
-
-
Brown, E.M.1
-
79
-
-
9644255750
-
Clinical and laboratory features of calcium-sensing receptor disorders: A systematic review
-
Gunn IR, Gaffney D 2004 Clinical and laboratory features of calcium-sensing receptor disorders: a systematic review. Ann Clin Biochem 41:441-458
-
(2004)
Ann Clin Biochem
, vol.41
, pp. 441-458
-
-
Gunn, I.R.1
Gaffney, D.2
-
80
-
-
0141839700
-
Extracellular calcium-sensing receptor dysfunction is associated with two new phenotypes
-
Sayer JA, Pearce SHS 2003 Extracellular calcium-sensing receptor dysfunction is associated with two new phenotypes. Clin Endocrinol 59:419-421
-
(2003)
Clin Endocrinol
, vol.59
, pp. 419-421
-
-
Sayer, J.A.1
Pearce, S.H.S.2
-
81
-
-
0030453451
-
Calcium-sensing receptor mutations in familial hy-pocalciuric hypercalcemia with recurrent pancreatitis
-
Pearce SH, Wooding C, Davies M, Tollefsen SE, Whyte MP, Thak-ker RV 1996 Calcium-sensing receptor mutations in familial hy-pocalciuric hypercalcemia with recurrent pancreatitis. Clin Endocrinol 45:675-680
-
(1996)
Clin Endocrinol
, vol.45
, pp. 675-680
-
-
Pearce, S.H.1
Wooding, C.2
Davies, M.3
Tollefsen, S.E.4
Whyte, M.P.5
Thak-ker, R.V.6
-
82
-
-
33644589788
-
Mutations in the calcium-sensing receptor: A new genetic risk factor for chronic pancreatitis?
-
Felderbauer P, Klein W, Bulut K, Ansorge N, Dekomien G, Werner I, Epplen JT, Schmitz F, Schmidt WE 2006 Mutations in the calcium-sensing receptor: a new genetic risk factor for chronic pancreatitis? Scand J Gastroenterol 41:343-348
-
(2006)
Scand J Gastroenterol
, vol.41
, pp. 343-348
-
-
Felderbauer, P.1
Klein, W.2
Bulut, K.3
Ansorge, N.4
Dekomien, G.5
Werner, I.6
Epplen, J.T.7
Schmitz, F.8
Schmidt, W.E.9
-
83
-
-
77951920963
-
Genetic aspects ofpancreatitis
-
Whitcomb DC 2010Genetic aspects ofpancreatitis. AnnuRev Med 61:413-424
-
(2010)
AnnuRev Med
, vol.61
, pp. 413-424
-
-
Whitcomb, D.C.1
-
84
-
-
0035176619
-
Activating mutations of the calcium-sensing receptor: Management of hypocalcemia
-
Lienhardt A, Bai M, Lagarde JP, Rigaud M, Zhang Z, Jiang Y, Kottler ML, Brown EM, Garabedian M 2001 Activating mutations of the calcium-sensing receptor: management of hypocalcemia. J Clin Endocrinol Metab 86:5313-5323
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 5313-5323
-
-
Lienhardt, A.1
Bai, M.2
Lagarde, J.P.3
Rigaud, M.4
Zhang, Z.5
Jiang, Y.6
Kottler, M.L.7
Brown, E.M.8
Garabedian, M.9
-
85
-
-
77957870933
-
Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels
-
O'Seaghdha CM, Yang Q, Glazer NL, Leak TS, Dehghan A, Smith AV, Kao WH, Lohman K, Hwang SJ, Johnson AD, Hofman A, Uitterlinden AG, Chen YD, Brown EM, Siscovick DS, Harris TB, Psaty BM, Coresh J, Gudnason V, Witteman JC, Liu YM, Kesten-baum BR, Fox CS, Kottgen A 2010 Common variants in the calcium-sensing receptor gene are associated with total serum calcium levels. Hum Mol Genet 19:4296-4303
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4296-4303
-
-
O'Seaghdha, C.M.1
Yang, Q.2
Glazer, N.L.3
Leak, T.S.4
Dehghan, A.5
Smith, A.V.6
Kao, W.H.7
Lohman, K.8
Hwang, S.J.9
Johnson, A.D.10
Hofman, A.11
Uitterlinden, A.G.12
Chen, Y.D.13
Brown, E.M.14
Siscovick, D.S.15
Harris, T.B.16
Psaty, B.M.17
Coresh, J.18
Gudnason, V.19
Witteman, J.C.20
Liu, Y.M.21
Kesten-baum, B.R.22
Fox, C.S.23
Kottgen, A.24
more..
-
86
-
-
34347237294
-
Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause and cardiovascular mortality
-
Marz W, Seelhorst U, Wellnitz B, Tiran B, Obermayer-Pietsch B, Renner W, Boehm BO, Ritz E, Hoffmann MM 2007 Alanine to serine polymorphism at position 986 of the calcium-sensing receptor associated with coronary heart disease, myocardial infarction, all-cause and cardiovascular mortality. J Clin Endocrinol Metab 92:2363-2369
-
(2007)
J Clin Endocrinol Metab
, vol.92
, pp. 2363-2369
-
-
Marz, W.1
Seelhorst, U.2
Wellnitz, B.3
Tiran, B.4
Obermayer-Pietsch, B.5
Renner, W.6
Boehm, B.O.7
Ritz, E.8
Hoffmann, M.M.9
-
88
-
-
81455162137
-
Calcium-sensing receptor and calcium kidney stones
-
Vezzoli G, Terranegra A, Rainone F, Arcidiacono T, Cozzolino M, Aloia A, Dogliotti E, Cusi D, Soldati L 2011 Calcium-sensing receptor and calcium kidney stones. J Transl Med 9:201
-
(2011)
J Transl Med
, vol.9
, pp. 201
-
-
Vezzoli, G.1
Terranegra, A.2
Rainone, F.3
Arcidiacono, T.4
Cozzolino, M.5
Aloia, A.6
Dogliotti, E.7
Cusi, D.8
Soldati, L.9
-
89
-
-
80051572183
-
Role of the calcium-sensing receptor in reducing the risk for calcium stones
-
Renkema KY, Bindels RJ, Hoenderop JG 2011 Role of the calcium-sensing receptor in reducing the risk for calcium stones. Clin J Am Soc Nephrol 6:2076-2082
-
(2011)
Clin J Am Soc Nephrol
, vol.6
, pp. 2076-2082
-
-
Renkema, K.Y.1
Bindels, R.J.2
Hoenderop, J.G.3
-
90
-
-
4544240827
-
Calcium-sensing receptor autoantibodies are relevant markers of acquired hypoparathyroidism
-
Mayer A, Ploix C, Orgiazzi J, Desbos A, Moreira A, Vidal H, Monier JC, Bienvenu J, Fabien N 2004 Calcium-sensing receptor autoantibodies are relevant markers of acquired hypoparathyroidism. J Clin Endocrinol Metab 89:4484-4488
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 4484-4488
-
-
Mayer, A.1
Ploix, C.2
Orgiazzi, J.3
Desbos, A.4
Moreira, A.5
Vidal, H.6
Monier, J.C.7
Bienvenu, J.8
Fabien, N.9
-
91
-
-
1442327820
-
Activating antibodies to the calcium-sensing receptor in two patients with autoimmune hypoparathyroidism
-
Kifor O, McElduff A, LeBoff MS, Moore Jr FD, Butters R, Gao P, Cantor TL, Kifor I, Brown EM 2004 Activating antibodies to the calcium-sensing receptor in two patients with autoimmune hypoparathyroidism. J Clin Endocrinol Metab 89:548-556
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 548-556
-
-
Kifor, O.1
McElduff, A.2
LeBoff, M.S.3
Moore Jr, F.D.4
Butters, R.5
Gao, P.6
Cantor, T.L.7
Kifor, I.8
Brown, E.M.9
-
92
-
-
0030051024
-
Autoantibodies to the extracellular domain of the calcium-sensing receptor in patients with acquired hypoparathyroidism
-
Li Y, Song YH, Rais N, Connor E, Schatz D, Muir A, Maclaren N 1996 Autoantibodies to the extracellular domain of the calcium-sensing receptor in patients with acquired hypoparathyroidism. J Clin Invest 97:910-914
-
(1996)
J Clin Invest
, vol.97
, pp. 910-914
-
-
Li, Y.1
Song, Y.H.2
Rais, N.3
Connor, E.4
Schatz, D.5
Muir, A.6
Maclaren, N.7
-
93
-
-
34248393065
-
An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations
-
Makita N, Sato J, Manaka K, Shoji Y, Oishi A, Hashimoto M, Fujita T, Iiri T 2007 An acquired hypocalciuric hypercalcemia autoantibody induces allosteric transition among active human Ca-sensing receptor conformations. Proc Natl Acad Sci USA 104: 5443-5448
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 5443-5448
-
-
Makita, N.1
Sato, J.2
Manaka, K.3
Shoji, Y.4
Oishi, A.5
Hashimoto, M.6
Fujita, T.7
Iiri, T.8
-
94
-
-
77953416752
-
Mapping of human autoantibody binding sites on the calcium-sensing receptor
-
Kemp EH, Gavalas NG, Akhtar S, Krohn KJ, Pallais JC, Brown EM, Watson PF, Weetman AP 2010 Mapping of human autoantibody binding sites on the calcium-sensing receptor. J Bone Miner Res 25:132-140
-
(2010)
J Bone Miner Res
, vol.25
, pp. 132-140
-
-
Kemp, E.H.1
Gavalas, N.G.2
Akhtar, S.3
Krohn, K.J.4
Pallais, J.C.5
Brown, E.M.6
Watson, P.F.7
Weetman, A.P.8
-
95
-
-
79959553911
-
Benign familial hypocalciuric hypercalcemia
-
Varghese J, Rich T, Jiminez C 2011 Benign familial hypocalciuric hypercalcemia. Endocr Pract 17(Suppl 1):13-17
-
(2011)
Endocr Pract
, vol.17
, Issue.SUPPL. 1
, pp. 13-17
-
-
Varghese, J.1
Rich, T.2
Jiminez, C.3
-
96
-
-
70350365883
-
The clinical significance of parathyroid tissue calcium sensing receptor gene polymorphisms and expression levels in end-stage renal disease
-
Eren PA, Turan K, Berber I, Canbakan M, Kara M, Tellioglu G, Bugan U, Sevin C, Turkmen F, Titiz MI 2009 The clinical significance of parathyroid tissue calcium sensing receptor gene polymorphisms and expression levels in end-stage renal disease. Clin Nephrol 72:114-121
-
(2009)
Clin Nephrol
, vol.72
, pp. 114-121
-
-
Eren, P.A.1
Turan, K.2
Berber, I.3
Canbakan, M.4
Kara, M.5
Tellioglu, G.6
Bugan, U.7
Sevin, C.8
Turkmen, F.9
Titiz, M.I.10
-
97
-
-
65249144951
-
The role of the calcium-sensing receptor in the development and progression of cancer
-
Saidak Z, Mentaverri R, Brown EM 2009 The role of the calcium-sensing receptor in the development and progression of cancer. Endocr Rev 30:178-195
-
(2009)
Endocr Rev
, vol.30
, pp. 178-195
-
-
Saidak, Z.1
Mentaverri, R.2
Brown, E.M.3
-
99
-
-
58549086726
-
Calcium, calcium-sensing receptor and colon cancer
-
Whitfield JF 2009 Calcium, calcium-sensing receptor and colon cancer. Cancer Lett 275:9-16
-
(2009)
Cancer Lett
, vol.275
, pp. 9-16
-
-
Whitfield, J.F.1
-
100
-
-
0038069520
-
Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas
-
Yano S, Sugimoto T, Tsukamoto T, Chihara K, Kobayashi A, Kitazawa S, Maeda S, Kitazawa R 2003 Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas. Eur J Endocrinol 148:403-411
-
(2003)
Eur J Endocrinol
, vol.148
, pp. 403-411
-
-
Yano, S.1
Sugimoto, T.2
Tsukamoto, T.3
Chihara, K.4
Kobayashi, A.5
Kitazawa, S.6
Maeda, S.7
Kitazawa, R.8
-
101
-
-
79957904432
-
Epigenetic inactivation of calcium-sensing receptor in colorectal carcinoma
-
Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y 2011 Epigenetic inactivation of calcium-sensing receptor in colorectal carcinoma. Mod Pathol 24:876-884
-
(2011)
Mod Pathol
, vol.24
, pp. 876-884
-
-
Hizaki, K.1
Yamamoto, H.2
Taniguchi, H.3
Adachi, Y.4
Nakazawa, M.5
Tanuma, T.6
Kato, N.7
Sukawa, Y.8
Sanchez, J.V.9
Suzuki, H.10
Sasaki, S.11
Imai, K.12
Shinomura, Y.13
-
102
-
-
67349148557
-
Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor
-
Saidak Z, Boudot C, Abdoune R, Petit L, Brazier M, Mentaverri R, Kamel S 2009 Extracellular calcium promotes the migration of breast cancer cells through the activation of the calcium sensing receptor. Exp Cell Res 315:2072-2080
-
(2009)
Exp Cell Res
, vol.315
, pp. 2072-2080
-
-
Saidak, Z.1
Boudot, C.2
Abdoune, R.3
Petit, L.4
Brazier, M.5
Mentaverri, R.6
Kamel, S.7
-
103
-
-
33646386892
-
Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy
-
Chattopadhyay N 2006 Effects of calcium-sensing receptor on the secretion of parathyroid hormone-related peptide and its impact on humoral hypercalcemia of malignancy. Am J Physiol Endocrinol Metab 290:E761-E770
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Chattopadhyay, N.1
-
104
-
-
0037119447
-
Human calcium-sensing receptor gene, vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D
-
Canaff L, Hendy GN 2002 Human calcium-sensing receptor gene, vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D. J Biol Chem 277:30337-30350
-
(2002)
J Biol Chem
, vol.277
, pp. 30337-30350
-
-
Canaff, L.1
Hendy, G.N.2
-
105
-
-
70349116510
-
Calcium-sensing receptor is regulated by glial cells missing-2 in human parathyroid cells
-
Mizobuchi M, Ritter CS, Krits I, Slatopolsky E, Sicard G, Brown AJ 2009 Calcium-sensing receptor is regulated by glial cells missing-2 in human parathyroid cells. J Bone Miner Res 24:11731179
-
(2009)
J Bone Miner Res
, vol.24
, pp. 11731179
-
-
Mizobuchi, M.1
Ritter, C.S.2
Krits, I.3
Slatopolsky, E.4
Sicard, G.5
Brown, A.J.6
-
106
-
-
17144375994
-
Calcium-sensing receptor gene transcription is up-regulated by the proinflammatory cytokine, interleukin-10. Role of the NF-KB pathway and KB elements
-
Canaff L, Hendy GN 2005 Calcium-sensing receptor gene transcription is up-regulated by the proinflammatory cytokine, interleukin-10. Role of the NF-KB pathway and KB elements. J Biol Chem 280:14177-14188
-
(2005)
J Biol Chem
, vol.280
, pp. 14177-14188
-
-
Canaff, L.1
Hendy, G.N.2
-
107
-
-
46649107165
-
The proinflammatory cytokine, interleukin-6, up-regulates calcium-sensing receptor gene transcription via Stat1/3 and Sp1/3
-
Canaff L, Zhou X, Hendy GN 2008 The proinflammatory cytokine, interleukin-6, up-regulates calcium-sensing receptor gene transcription via Stat1/3 and Sp1/3. J Biol Chem 283:1358613600
-
(2008)
J Biol Chem
, vol.283
, pp. 1358613600
-
-
Canaff, L.1
Zhou, X.2
Hendy, G.N.3
-
108
-
-
0034678069
-
Cloning and characterization of two promoters for the human calcium-sensing receptor (CaSR) and changes of CaSR expression in parathyroid adenomas
-
Chikatsu N, Fukumoto S, Takeuchi Y, Suzawa M, Obara T, Ma-tsumoto T, Fujita T 2000 Cloning and characterization of two promoters for the human calcium-sensing receptor (CaSR) and changes of CaSR expression in parathyroid adenomas. J Biol Chem 275:7553-7557
-
(2000)
J Biol Chem
, vol.275
, pp. 7553-7557
-
-
Chikatsu, N.1
Fukumoto, S.2
Takeuchi, Y.3
Suzawa, M.4
Obara, T.5
Ma-tsumoto, T.6
Fujita, T.7
-
109
-
-
0035947035
-
Calcium-and vitamin D-regulated keratinocyte differentiation
-
Bikle DD, Ng D, Tu CL, Oda Y, Xie Z 2001 Calcium-and vitamin D-regulated keratinocyte differentiation. Mol Cell Endocrinol 177:161-171
-
(2001)
Mol Cell Endocrinol
, vol.177
, pp. 161-171
-
-
Bikle, D.D.1
Ng, D.2
Tu, C.L.3
Oda, Y.4
Xie, Z.5
-
110
-
-
1442277004
-
The role of the calcium-sensing receptor in epidermal differentiation
-
Tu CL, Oda Y, Komuves L, Bikle DD 2004 The role of the calcium-sensing receptor in epidermal differentiation. Cell Calcium 35:265-273
-
(2004)
Cell Calcium
, vol.35
, pp. 265-273
-
-
Tu, C.L.1
Oda, Y.2
Komuves, L.3
Bikle, D.D.4
-
111
-
-
15444340724
-
The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation
-
Oda Y, Tu CL, Pillai S, Bikle DD 1998 The calcium sensing receptor and its alternatively spliced form in keratinocyte differentiation. J BIol Chem 273:23344-23352
-
(1998)
J BIol Chem
, vol.273
, pp. 23344-23352
-
-
Oda, Y.1
Tu, C.L.2
Pillai, S.3
Bikle, D.D.4
-
112
-
-
0033966937
-
The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation
-
Oda Y, Tu CL, Chang W, Crumrine D, Komuves L, Mauro T, Elias PM, Bikle DD 2000 The calcium sensing receptor and its alternatively spliced form in murine epidermal differentiation. J Biol Chem 275:1183-1190
-
(2000)
J Biol Chem
, vol.275
, pp. 1183-1190
-
-
Oda, Y.1
Tu, C.L.2
Chang, W.3
Crumrine, D.4
Komuves, L.5
Mauro, T.6
Elias, P.M.7
Bikle, D.D.8
-
113
-
-
0035798614
-
The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes
-
Tu CL, Chang W, Bikle DD 2001 The extracellular calcium-sensing receptor is required for calcium-induced differentiation in human keratinocytes. J Biol Chem 276:41079-41085
-
(2001)
J Biol Chem
, vol.276
, pp. 41079-41085
-
-
Tu, C.L.1
Chang, W.2
Bikle, D.D.3
-
114
-
-
0035163266
-
An acceptor splice site mutation in the calcium-sensing receptor (CASR) gene in familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism
-
D'Souza-Li L, Canaff L, Janicic N, Cole DE, Hendy GN 2001 An acceptor splice site mutation in the calcium-sensing receptor (CASR) gene in familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Hum Mutat 18:411-421
-
(2001)
Hum Mutat
, vol.18
, pp. 411-421
-
-
D'Souza-Li, L.1
Canaff, L.2
Janicic, N.3
Cole, D.E.4
Hendy, G.N.5
-
115
-
-
33646820680
-
Expression of the calcium receptor in human breast cancer-a potential new marker predicting risk of bone metastases
-
Mihai R, Stevens J, McKinney C, Ibrahim NB 2006 Expression of the calcium receptor in human breast cancer-a potential new marker predicting risk of bone metastases. Eur J Surg Oncol 32: 511-515
-
(2006)
Eur J Surg Oncol
, vol.32
, pp. 511-515
-
-
Mihai, R.1
Stevens, J.2
McKinney, C.3
Ibrahim, N.B.4
-
116
-
-
77955049339
-
Quality and quantity control at the endoplasmic reticulum
-
Hegde RS, Ploegh HL 2010 Quality and quantity control at the endoplasmic reticulum. Curr Opin Cell Biol 22:437-446
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 437-446
-
-
Hegde, R.S.1
Ploegh, H.L.2
-
117
-
-
79959481888
-
Protein folding and modification in the mammalian endoplasmic reticulum
-
Braakman I, Bulleid NJ 2011 Protein folding and modification in the mammalian endoplasmic reticulum. Annu Rev Biochem 80: 71-99
-
(2011)
Annu Rev Biochem
, vol.80
, pp. 71-99
-
-
Braakman, I.1
Bulleid, N.J.2
-
118
-
-
34248139121
-
Rescue of calcium-sensing receptor mutants by allosteric modulators reveals a conformational checkpoint in receptor biogenesis
-
Huang Y, Breitwieser GE 2007 Rescue of calcium-sensing receptor mutants by allosteric modulators reveals a conformational checkpoint in receptor biogenesis. J Biol Chem 282:9517-9525
-
(2007)
J Biol Chem
, vol.282
, pp. 9517-9525
-
-
Huang, Y.1
Breitwieser, G.E.2
-
119
-
-
67649619319
-
Phar-macochaperone-mediated rescue of calcium-sensing receptor loss-of-function mutants
-
White E, McKenna J, Cavanaugh A, Breitwieser GE 2009 Phar-macochaperone-mediated rescue of calcium-sensing receptor loss-of-function mutants. Mol Endocrinol 23:1115-1123
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1115-1123
-
-
White, E.1
McKenna, J.2
Cavanaugh, A.3
Breitwieser, G.E.4
-
120
-
-
63849209036
-
Targeting of G protein-coupled receptor to the plasma membrane in health and disease
-
Ulloa-Aguirre A, Conn PM 2009 Targeting of G protein-coupled receptor to the plasma membrane in health and disease. Front Biosci 14:973-994
-
(2009)
Front Biosci
, vol.14
, pp. 973-994
-
-
Ulloa-Aguirre, A.1
Conn, P.M.2
-
121
-
-
34748871331
-
G protein-coupled receptor trafficking in health and disease: Lessons learned to prepare for therapeutic mutant rescue in vivo
-
Conn PM, Ulloa-Aguirre A, Ito J, Janovick JA 2007 G protein-coupled receptor trafficking in health and disease: lessons learned to prepare for therapeutic mutant rescue in vivo. Pharmacol Rev 59:225-250
-
(2007)
Pharmacol Rev
, vol.59
, pp. 225-250
-
-
Conn, P.M.1
Ulloa-Aguirre, A.2
Ito, J.3
Janovick, J.A.4
-
122
-
-
33745167938
-
Protein-misfolding diseases and chaperone-based therapeutic approaches
-
1331-1249
-
Chaudhuri TK, Paul S 2006 Protein-misfolding diseases and chaperone-based therapeutic approaches. FEBS J 273:1331-1249
-
(2006)
FEBS J
, vol.273
-
-
Chaudhuri, T.K.1
Paul, S.2
-
123
-
-
34547105186
-
Chemical and pharmacological chaperones as the new therapeutic agents
-
Loo TW, Clarke DM 2007 Chemical and pharmacological chaperones as the new therapeutic agents. Expert Rev Mol Med 9:1-18
-
(2007)
Expert Rev Mol Med
, vol.9
, pp. 1-18
-
-
Loo, T.W.1
Clarke, D.M.2
-
124
-
-
16644366865
-
Pharmacological chaperone action on G-protein-coupled receptors
-
Bernier V, Bichet DG, Bouvier M 2004 Pharmacological chaperone action on G-protein-coupled receptors. Curr Opin Pharmacol 4:528-533
-
(2004)
Curr Opin Pharmacol
, vol.4
, pp. 528-533
-
-
Bernier, V.1
Bichet, D.G.2
Bouvier, M.3
-
125
-
-
34548159460
-
Opioid receptor pharmacological chaperones act by binding and stabilizing newly synthesized receptor in the endoplasmic reticulum
-
Leskela TT, Markkanen PM, Pietila EM, Tuusa JT, Petaja-Repo UE 2007 Opioid receptor pharmacological chaperones act by binding and stabilizing newly synthesized receptor in the endoplasmic reticulum. J Biol Chem 282:23171-23183
-
(2007)
J Biol Chem
, vol.282
, pp. 23171-23183
-
-
Leskela, T.T.1
Markkanen, P.M.2
Pietila, E.M.3
Tuusa, J.T.4
Petaja-Repo, U.E.5
-
126
-
-
8744236215
-
Pharma-cochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors
-
Wuller S, Wiesner B, Loffler A, FurkertJ, Krause G, Hermosilla R, Schaefer M, Schulein R, Rosenthal W, Oksche A 2004 Pharma-cochaperones post-translationally enhance cell surface expression by increasing conformational stability of wild-type and mutant vasopressin V2 receptors. J Biol Chem 279:47254-47263
-
(2004)
J Biol Chem
, vol.279
, pp. 47254-47263
-
-
Wuller, S.1
Wiesner, B.2
Loffler, A.3
Furkert, J.4
Krause, G.5
Hermosilla, R.6
Schaefer, M.7
Schulein, R.8
Rosenthal, W.9
Oksche, A.10
-
127
-
-
34249712933
-
Pharmacological chaperones in nephrogenic diabetes insipidus: Possibilities for clinical application
-
Robben JH, Deen PM 2007 Pharmacological chaperones in nephrogenic diabetes insipidus: possibilities for clinical application. BioDrugs 21:157-166
-
(2007)
BioDrugs
, vol.21
, pp. 157-166
-
-
Robben, J.H.1
Deen, P.M.2
-
128
-
-
77956119735
-
Potential of nonpeptide (an-t)agonists to rescue vasopressin V2 receptor mutants for the treatment of X-linked diabetes insipidus
-
Los EL, Deen PM, Robben JH 2010 Potential of nonpeptide (an-t)agonists to rescue vasopressin V2 receptor mutants for the treatment of X-linked diabetes insipidus. J Neuroendocrinol 22:393399
-
(2010)
J Neuroendocrinol
, vol.22
, pp. 393399
-
-
Los, E.L.1
Deen, P.M.2
Robben, J.H.3
-
129
-
-
20444375156
-
Nicotine upregulates its own receptor through enhanced intracellular maturation
-
Sallette J, Pons S, Devillers-Thiery A, Soudant M, Prado de Carvalho L, Changeux JP, Corringer PJ 2005 Nicotine upregulates its own receptor through enhanced intracellular maturation. Neuron 46:595-607
-
(2005)
Neuron
, vol.46
, pp. 595-607
-
-
Sallette, J.1
Pons, S.2
Devillers-Thiery, A.3
Soudant, M.4
de Prado Carvalho, L.5
Changeux, J.P.6
Corringer, P.J.7
-
130
-
-
78650873492
-
Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning
-
Srinivasan R, Pantoja R, Moss FJ, Mackey ED, Son CD, Miwa J, Lester HA 2011 Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning. J Gen Physiol 137:59-79
-
(2011)
J Gen Physiol
, vol.137
, pp. 59-79
-
-
Srinivasan, R.1
Pantoja, R.2
Moss, F.J.3
Mackey, E.D.4
Son, C.D.5
Miwa, J.6
Lester, H.A.7
-
131
-
-
14644444154
-
Glutamate receptor trafficking: Endoplasmic reticulum quality control involves ligand binding and receptor function
-
Mah SJ, Cornell E, Mitchell NA, Fleck MW 2005 Glutamate receptor trafficking: endoplasmic reticulum quality control involves ligand binding and receptor function. J Neurosci 25:22152225
-
(2005)
J Neurosci
, vol.25
, pp. 22152225
-
-
Mah, S.J.1
Cornell, E.2
Mitchell, N.A.3
Fleck, M.W.4
-
132
-
-
56549086986
-
Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum
-
Penn AC, Williams SR, Greger IH 2008 Gating motions underlie AMPA receptor secretion from the endoplasmic reticulum. EMBO J 27:3056-3068
-
(2008)
EMBO J
, vol.27
, pp. 3056-3068
-
-
Penn, A.C.1
Williams, S.R.2
Greger, I.H.3
-
133
-
-
33646846296
-
Activation of family C G-protein-coupled receptors by tripeptide glutathione
-
Wang M, Yao Y, Kuang D, Hampson DR 2006 Activation of family C G-protein-coupled receptors by tripeptide glutathione. J Biol Chem 281:8864-8870
-
(2006)
J Biol Chem
, vol.281
, pp. 8864-8870
-
-
Wang, M.1
Yao, Y.2
Kuang, D.3
Hampson, D.R.4
-
134
-
-
33645784167
-
The role of glutathione in disulfide bond formation and endoplasmic-reticulum-generated oxidative stress
-
Chakravarthi S, Jessop CE, Bulleid NJ 2006 The role of glutathione in disulfide bond formation and endoplasmic-reticulum-generated oxidative stress. EMBO Rep 7:271-275
-
(2006)
EMBO Rep
, vol.7
, pp. 271-275
-
-
Chakravarthi, S.1
Jessop, C.E.2
Bulleid, N.J.3
-
135
-
-
33645980003
-
Endoplasmic reticulum: A metabolic compartment
-
Csala M, Banhegyi G, BenedettiA 2006 Endoplasmic reticulum: a metabolic compartment. FEBS Lett 580:2160-2165
-
(2006)
FEBS Lett
, vol.580
, pp. 2160-2165
-
-
Csala, M.1
Banhegyi, G.2
Benedetti, A.3
-
136
-
-
79953199013
-
Allosteric modulation of the calcium-sensing receptor by γ-glutamyl peptides: Inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids
-
Broadhead GK, Mun HC, Avlani VA, Jourdon O, Church WB, Christopoulos A, Delbridge L, Conigrave AD 2011 Allosteric modulation of the calcium-sensing receptor by γ-glutamyl peptides: inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids. J Biol Chem 286:8786-8797
-
(2011)
J Biol Chem
, vol.286
, pp. 8786-8797
-
-
Broadhead, G.K.1
Mun, H.C.2
Avlani, V.A.3
Jourdon, O.4
Church, W.B.5
Christopoulos, A.6
Delbridge, L.7
Conigrave, A.D.8
-
137
-
-
79960247207
-
Calcium homeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress
-
Gallego-Sandin S, Alonso MT, Garcia-Sancho J 2011 Calcium homeostasis modulator 1 (CALHM1) reduces the calcium content of the endoplasmic reticulum (ER) and triggers ER stress. Biochem J 437:469-475
-
(2011)
Biochem J
, vol.437
, pp. 469-475
-
-
Gallego-Sandin, S.1
Alonso, M.T.2
Garcia-Sancho, J.3
-
138
-
-
80054776671
-
Endoplasmic reticulum calcium depletion and disease
-
pii:a004317
-
Mekahli D, Bultynck G, Parys JB, De Smedt H, Missiaen L 2011 Endoplasmic reticulum calcium depletion and disease. Cold Spring Harb Perspect Biol 3:pii:a004317
-
(2011)
Cold Spring Harb Perspect Biol
, vol.3
-
-
Mekahli, D.1
Bultynck, G.2
Parys, J.B.3
de Smedt, H.4
Missiaen, L.5
-
139
-
-
38349049487
-
S-glutathionylation: Indicator of cell stress and regulator of the unfolded protein response
-
Townsend DM 2007 S-glutathionylation: indicator of cell stress and regulator of the unfolded protein response. Mol Interv 7:313324
-
(2007)
Mol Interv
, vol.7
, pp. 313324
-
-
Townsend, D.M.1
-
140
-
-
51349088530
-
Molecular mechanisms and clinical implications of reversible protein S-glutathionylation
-
Mieyal JJ, Gallogly MM, Qanungo S, Savens EA, Shelton MD 2008 Molecular mechanisms and clinical implications of reversible protein S-glutathionylation. Antiox Redox Signal 10:19411988
-
(2008)
Antiox Redox Signal
, vol.10
, pp. 19411988
-
-
Mieyal, J.J.1
Gallogly, M.M.2
Qanungo, S.3
Savens, E.A.4
Shelton, M.D.5
-
141
-
-
79953899942
-
Allosteric modulation of family C G-protein-coupled receptors: From molecular insights to therapeutic perspectives
-
Urwyler S 2011 Allosteric modulation of family C G-protein-coupled receptors: from molecular insights to therapeutic perspectives. Pharmacol Rev 63:59-126
-
(2011)
Pharmacol Rev
, vol.63
, pp. 59-126
-
-
Urwyler, S.1
-
142
-
-
73349103466
-
Effect of the calcimimetic R-568 [3-(2-chlorophenyl)-N-(1R)-1-(3-methylphenyl)ethyl)-1-propanamine] on correcting inactivating mutations in the human calcium-sensing receptor
-
Lu JY, Yang Y, Gnacadja G, Christopoulos A, Reagan JD 2009 Effect of the calcimimetic R-568 [3-(2-chlorophenyl)-N-(1R)-1-(3-methylphenyl)ethyl)-1-propanamine] on correcting inactivating mutations in the human calcium-sensing receptor. J Pharmacol Ther 331:775-786
-
(2009)
J Pharmacol Ther
, vol.331
, pp. 775-786
-
-
Lu, J.Y.1
Yang, Y.2
Gnacadja, G.3
Christopoulos, A.4
Reagan, J.D.5
-
143
-
-
33745893799
-
Normalization of serum calcium by cinacalcet in a patient with hypercalcaemia due to a de novo inactivating mutation of the calcium-sensing receptor
-
Timmers HJ, Karperien M, Hamdy NA, de Boer H, Hermus AR 2006 Normalization of serum calcium by cinacalcet in a patient with hypercalcaemia due to a de novo inactivating mutation of the calcium-sensing receptor. J Intern Med 260:177-182
-
(2006)
J Intern Med
, vol.260
, pp. 177-182
-
-
Timmers, H.J.1
Karperien, M.2
Hamdy, N.A.3
de Boer, H.4
Hermus, A.R.5
-
144
-
-
77954978874
-
Beneficial effect of cinacalcet in a child with familial hypocalciuric hypercalcemia
-
Alon US, VandeVoorde RG 2010 Beneficial effect of cinacalcet in a child with familial hypocalciuric hypercalcemia. Pediatr Nephrol 25:1747-1750
-
(2010)
Pediatr Nephrol
, vol.25
, pp. 1747-1750
-
-
Alon, U.S.1
VandeVoorde, R.G.2
-
145
-
-
77957785182
-
Novel activating mutations of the calcium-sensing receptor: The calcilytic NPS-2143 mitigates excessive signal transduction of mutant receptors
-
Letz S, Rus R, Haag C, Dorr HG, Schnabel D, Mohlig M, Schulze E, Frank-Raue K, Raue F, Mayr B, Schofl C 2010 Novel activating mutations of the calcium-sensing receptor: the calcilytic NPS-2143 mitigates excessive signal transduction of mutant receptors. J Clin Endocrinol Metab 95:E229-E233
-
(2010)
J Clin Endocrinol Metab
, vol.95
-
-
Letz, S.1
Rus, R.2
Haag, C.3
Dorr, H.G.4
Schnabel, D.5
Mohlig, M.6
Schulze, E.7
Frank-Raue, K.8
Raue, F.9
Mayr, B.10
Schofl, C.11
-
146
-
-
77953361682
-
Clinical utility of calcimimetics targeting the extracellular calcium-sensing receptor (CaSR)
-
Brown EM 2010 Clinical utility of calcimimetics targeting the extracellular calcium-sensing receptor (CaSR). Biochem Pharmacol 80:297-307
-
(2010)
Biochem Pharmacol
, vol.80
, pp. 297-307
-
-
Brown, E.M.1
-
147
-
-
84863115494
-
Behind the curtain: Cellular mechanisms for allosteric modulation of calcium sensing receptors
-
Cavanaugh A, Huang Y, Breitwieser GE 2012 Behind the curtain: cellular mechanisms for allosteric modulation of calcium sensing receptors. Br J Pharmacol 6:1670-1677
-
(2012)
Br J Pharmacol
, vol.6
, pp. 1670-1677
-
-
Cavanaugh, A.1
Huang, Y.2
Breitwieser, G.E.3
-
148
-
-
80052683888
-
Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones
-
Huang Y, Cavanaugh A, Breitwieser GE 2011 Regulation of stability and trafficking of calcium-sensing receptors by pharmacologic chaperones. Adv Pharmacol 62:143-173
-
(2011)
Adv Pharmacol
, vol.62
, pp. 143-173
-
-
Huang, Y.1
Cavanaugh, A.2
Breitwieser, G.E.3
-
149
-
-
18244363907
-
The calcium-sensing receptor in normal physiology and pathophysiology: A review
-
Tfelt-Hansen J, Brown EM 2005 The calcium-sensing receptor in normal physiology and pathophysiology: a review. Crit Rev Clin Lab Sci 42:35-70
-
(2005)
Crit Rev Clin Lab Sci
, vol.42
, pp. 35-70
-
-
Tfelt-Hansen, J.1
Brown, E.M.2
-
150
-
-
0032491497
-
A carboxyl-terminal domain controls the cooperativity for extracellular Ca2+ activation of the human calcium sensing receptor: A study with receptor-green fluorescent protein fusions
-
Gama L, Breitwieser GE 1998 A carboxyl-terminal domain controls the cooperativity for extracellular Ca2+ activation of the human calcium sensing receptor: a study with receptor-green fluorescent protein fusions. J BIol Chem 273:29712-29718
-
(1998)
J BIol Chem
, vol.273
, pp. 29712-29718
-
-
Gama, L.1
Breitwieser, G.E.2
-
151
-
-
0037147216
-
Calcium sensing receptor activation by a calcimimetic suggests a link between coop-erativity and intracellular calcium oscillations
-
Miedlich SU, Gama L, Breitwieser GE 2002 Calcium sensing receptor activation by a calcimimetic suggests a link between coop-erativity and intracellular calcium oscillations. J Biol Chem 277: 29591-29599
-
(2002)
J Biol Chem
, vol.277
, pp. 29591-29599
-
-
Miedlich, S.U.1
Gama, L.2
Breitwieser, G.E.3
-
152
-
-
1442350459
-
Calcium-sensing receptors as integrators of multiple metabolic signals
-
Breitwieser GE, Miedlich SU, Zhang M 2004 Calcium-sensing receptors as integrators of multiple metabolic signals. Cell Calcium 35:209-216
-
(2004)
Cell Calcium
, vol.35
, pp. 209-216
-
-
Breitwieser, G.E.1
Miedlich, S.U.2
Zhang, M.3
-
153
-
-
15444378518
-
β-Arrestin-and G protein receptor kinase-mediated calcium-sensing receptor desensitization
-
Pi M, Oakley RH, Gesty-Palmer D, Cruickshank RD, Spurney RF, Luttrell LM, Quarles LD 2005 β-Arrestin-and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol 19:1078-1087
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1078-1087
-
-
Pi, M.1
Oakley, R.H.2
Gesty-Palmer, D.3
Cruickshank, R.D.4
Spurney, R.F.5
Luttrell, L.M.6
Quarles, L.D.7
-
154
-
-
34249824302
-
Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinct mechanisms: Role of G protein-coupled receptor kinases, protein kinase C and β-arrestins
-
LorenzS, FrenzelR, Paschke R, BreitwieserGE, MiedlichSU 2007 Functional desensitization of the extracellular calcium-sensing receptor is regulated via distinct mechanisms: role of G protein-coupled receptor kinases, protein kinase C and β-arrestins. Endocrinology 148:2398-2404
-
(2007)
Endocrinology
, vol.148
, pp. 2398-2404
-
-
Lorenz, S.1
Frenzel, R.2
Paschke, R.3
Breitwieser, G.E.4
Miedlich, S.U.5
-
155
-
-
34247269159
-
The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes
-
Tu CL, Chang W, Bikle DD 2007 The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol 127:1074-1083
-
(2007)
J Invest Dermatol
, vol.127
, pp. 1074-1083
-
-
Tu, C.L.1
Chang, W.2
Bikle, D.D.3
-
156
-
-
0034495967
-
Dietary phosphate and parathyroid hormone alter the expression of the calcium-sensing receptor (CaR) and the Na+-dependent Pi transporter (NaPi-2) in the ratproximal tubule
-
Riccardi D, Traebert M, Ward DT, Kaissling B, Biber J, Hebert SC, Murer H 2000 Dietary phosphate and parathyroid hormone alter the expression of the calcium-sensing receptor (CaR) and the Na+-dependent Pi transporter (NaPi-2) in the ratproximal tubule. Pflugers Arch 441:379-387
-
(2000)
Pflugers Arch
, vol.441
, pp. 379-387
-
-
Riccardi, D.1
Traebert, M.2
Ward, D.T.3
Kaissling, B.4
Biber, J.5
Hebert, S.C.6
Murer, H.7
-
157
-
-
18544399263
-
Calcium-sensing receptor in rat hippocampus: A developmental study
-
Chattopadhyay N, Legradi G, Bai M, Kifor O, YeC, Vassilev PM, Brown EM, Lechan RM 1997 Calcium-sensing receptor in rat hippocampus: a developmental study. Dev Brain Res 100:13-21
-
(1997)
Dev Brain Res
, vol.100
, pp. 13-21
-
-
Chattopadhyay, N.1
Legradi, G.2
Bai, M.3
Kifor, O.4
Ye, C.5
Vassilev, P.M.6
Brown, E.M.7
Lechan, R.M.8
-
158
-
-
0032014951
-
Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney
-
Riccardi D, Hall AE, Chattopadhyay N, Xu JZ, Brown EM, Hebert SC 1998 Localization of the extracellular Ca2+/polyvalent cation-sensing protein in rat kidney. AM J Physiol Renal Physiol 274:F611-F622
-
(1998)
AM J Physiol Renal Physiol
, vol.274
-
-
Riccardi, D.1
Hall, A.E.2
Chattopadhyay, N.3
Xu, J.Z.4
Brown, E.M.5
Hebert, S.C.6
-
159
-
-
0033575259
-
Molecular and functional identification of a Ca2+ (polyvalent cation)-sensing receptor in rat pancreas
-
Bruce JI, Yang X, Ferguson CJ, Elliott AC, Steward MC, Case RM, Riccardi D 1999 Molecular and functional identification of a Ca2+ (polyvalent cation)-sensing receptor in rat pancreas. J Biol Chem 274:20561-20568
-
(1999)
J Biol Chem
, vol.274
, pp. 20561-20568
-
-
Bruce, J.I.1
Yang, X.2
Ferguson, C.J.3
Elliott, A.C.4
Steward, M.C.5
Case, R.M.6
Riccardi, D.7
-
160
-
-
1642292051
-
Desensitization of G protein-coupled receptors and neuronal functions
-
Gainetdinov RR, Premont RT, Bohn LM, Lefkowitz RJ, Caron MG 2004 Desensitization of G protein-coupled receptors and neuronal functions. Annu Rev Neurosci 27:107-144
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 107-144
-
-
Gainetdinov, R.R.1
Premont, R.T.2
Bohn, L.M.3
Lefkowitz, R.J.4
Caron, M.G.5
-
161
-
-
77952415656
-
Beyond desensitization: Physiological relevance of arrestin-dependent signaling
-
Luttrell LM, Gesty-Palmer D 2010 Beyond desensitization: physiological relevance of arrestin-dependent signaling. Pharmacol Rev 62:305-330
-
(2010)
Pharmacol Rev
, vol.62
, pp. 305-330
-
-
Luttrell, L.M.1
Gesty-Palmer, D.2
-
162
-
-
28844478334
-
Genetic variation in G-protein-coupled receptors-consequences for G-protein-coupled receptors as drug targets
-
Tang CM, Insel PA 2005 Genetic variation in G-protein-coupled receptors-consequences for G-protein-coupled receptors as drug targets. Expert Opin Ther Targets 9:1247-1265
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 1247-1265
-
-
Tang, C.M.1
Insel, P.A.2
-
163
-
-
79951970393
-
Transcriptional and epigenetic regulation of opioid receptor genes: Present and future
-
Wei LN, Loh HH 2011 Transcriptional and epigenetic regulation of opioid receptor genes: present and future. Annu Rev Pharmacol Toxicol 51:75-97
-
(2011)
Annu Rev Pharmacol Toxicol
, vol.51
, pp. 75-97
-
-
Wei, L.N.1
Loh, H.H.2
-
164
-
-
65549119281
-
Regulation of transcription factors by heterotrimeric G proteins
-
Ho MK, Su Y, Yeung WW, Wong YH 2009 Regulation of transcription factors by heterotrimeric G proteins. Curr Mol Pharmacol 2:19-31
-
(2009)
Curr Mol Pharmacol
, vol.2
, pp. 19-31
-
-
Ho, M.K.1
Su, Y.2
Yeung, W.W.3
Wong, Y.H.4
-
165
-
-
33846998992
-
β-Arrestin signaling and regulation of transcription
-
Ma L, Pei G 2007 β-Arrestin signaling and regulation of transcription. J Cell Sci 120:213-218
-
(2007)
J Cell Sci
, vol.120
, pp. 213-218
-
-
Ma, L.1
Pei, G.2
-
166
-
-
8844266127
-
Disease-causing V2 vasopressin receptors are retained in different compartments of the early secretory pathway
-
Hermosilla R, Oueslati M, Donalies U. Schonenberger E, Krause E, Oksche A, Rosenthal W, Schulein R 2004 Disease-causing V2 vasopressin receptors are retained in different compartments of the early secretory pathway. Traffic 4:993-1005
-
(2004)
Traffic
, vol.4
, pp. 993-1005
-
-
Hermosilla, R.1
Oueslati, M.2
Donalies, U.3
Schonenberger, E.4
Krause, E.5
Oksche, A.6
Rosenthal, W.7
Schulein, R.8
-
167
-
-
0037099080
-
The cellular fate of mutant rhodopsin: Quality control, degradation and aggresome formation
-
Saliba RS, Munro PM, Luthert PJ, Cheetham ME 2002 The cellular fate of mutant rhodopsin: quality control, degradation and aggresome formation. J Cell Sci 115:2907-2918
-
(2002)
J Cell Sci
, vol.115
, pp. 2907-2918
-
-
Saliba, R.S.1
Munro, P.M.2
Luthert, P.J.3
Cheetham, M.E.4
-
168
-
-
57649139756
-
N-glycan-mediated quality control in the endoplasmic reticulum is required for expression of correctly folded δ-opioid receptors at the cell surface
-
Markkanen PM, Petaja-Repo UE 2008 N-glycan-mediated quality control in the endoplasmic reticulum is required for expression of correctly folded δ-opioid receptors at the cell surface. J Biol Chem 283:29086-29098
-
(2008)
J Biol Chem
, vol.283
, pp. 29086-29098
-
-
Markkanen, P.M.1
Petaja-Repo, U.E.2
-
169
-
-
40849147267
-
Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasporessin receptors
-
Schwieger I, Lautz K, Krause E, Rosenthal W, Wiesner B, Her-mosilla R 2008 Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasporessin receptors. Mol Pharmacol 73:697-708
-
(2008)
Mol Pharmacol
, vol.73
, pp. 697-708
-
-
Schwieger, I.1
Lautz, K.2
Krause, E.3
Rosenthal, W.4
Wiesner, B.5
Her-mosilla, R.6
-
170
-
-
34648833641
-
N-glycosylation of the human κ-opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway
-
Li JG, Chen C, Liu-Chen LY 2007 N-glycosylation of the human κ-opioid receptor enhances its stability but slows its trafficking along the biosynthesis pathway. Biochemistry 46:10960-10970
-
(2007)
Biochemistry
, vol.46
, pp. 10960-10970
-
-
Li, J.G.1
Chen, C.2
Liu-Chen, L.Y.3
-
171
-
-
80053929969
-
Inhibition of biosynthesis of human endothelin B receptor by the cyclodepsipeptide cotransin
-
Westendorf C, Schmidt A, Coin I, FurkertJ, Ridelis I, Zampatis D, Rutz C, Wiesner B, Rosenthal W, Beyermann M, Schulein R 2011 Inhibition of biosynthesis of human endothelin B receptor by the cyclodepsipeptide cotransin. J Biol Chem 286:35588-35600
-
(2011)
J Biol Chem
, vol.286
, pp. 35588-35600
-
-
Westendorf, C.1
Schmidt, A.2
Coin, I.3
Furkert, J.4
Ridelis, I.5
Zampatis, D.6
Rutz, C.7
Wiesner, B.8
Rosenthal, W.9
Beyermann, M.10
Schulein, R.11
-
173
-
-
41149090339
-
Regulation of GPCRs by endocytic membrane trafficking and its potential implications
-
Hanyaloglu AC, von Zastrow M 2008 Regulation of GPCRs by endocytic membrane trafficking and its potential implications. Annu Rev Pharmacol Toxicol 48:537-568
-
(2008)
Annu Rev Pharmacol Toxicol
, vol.48
, pp. 537-568
-
-
Hanyaloglu, A.C.1
von Zastrow, M.2
-
174
-
-
77955706561
-
G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors
-
Moser E, Kargl J, Whistler JL, Waldhoer M, Tschische P 2010 G protein-coupled receptor-associated sorting protein 1 regulates the postendocytic sorting of seven-transmembrane-spanning G protein-coupled receptors. Pharmacology 85:22-29
-
(2010)
Pharmacology
, vol.85
, pp. 22-29
-
-
Moser, E.1
Kargl, J.2
Whistler, J.L.3
Waldhoer, M.4
Tschische, P.5
-
175
-
-
79959333069
-
Can-nabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway
-
Grimsey NL, Goodfellow CE, Dragunow M, Glass M 2011 Can-nabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway. Biochim BIophys Acta 1813:1554-1560
-
(2011)
Biochim BIophys Acta
, vol.1813
, pp. 1554-1560
-
-
Grimsey, N.L.1
Goodfellow, C.E.2
Dragunow, M.3
Glass, M.4
-
176
-
-
0037155272
-
Rapid internalization and recycling of the human neuropeptide YY1 receptor
-
Gicquiaux H, Lecat S, Gaire M, Dieterlen A, Mely Y, Takeda K, Bucher B, Galzi JL 2002 Rapid internalization and recycling of the human neuropeptide YY1 receptor. J Biol Chem 277:6645-6655
-
(2002)
J Biol Chem
, vol.277
, pp. 6645-6655
-
-
Gicquiaux, H.1
Lecat, S.2
Gaire, M.3
Dieterlen, A.4
Mely, Y.5
Takeda, K.6
Bucher, B.7
Galzi, J.L.8
-
177
-
-
0035952645
-
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
-
Pierce KL, Luttrell LM, Lefkowitz RJ 2001 New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades. Oncogene 20:1532-1539
-
(2001)
Oncogene
, vol.20
, pp. 1532-1539
-
-
Pierce, K.L.1
Luttrell, L.M.2
Lefkowitz, R.J.3
-
178
-
-
0034711397
-
β-Arrestin 2: A receptor-regulated MAPK scaffold for the activation of JNK3
-
McDonald PH, Chow CW, Miller WE, Laporte SA, Field ME, Lin FT, Davis RJ, Lefkowitz RJ 2000 β-Arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3. Science 290: 1574-1577
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
Chow, C.W.2
Miller, W.E.3
Laporte, S.A.4
Field, M.E.5
Lin, F.T.6
Davis, R.J.7
Lefkowitz, R.J.8
-
179
-
-
0141483377
-
A β-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced che-motaxis
-
Ge L, Ly Y, Hollenberg M, DeFea K 2003 A β-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced che-motaxis. J Biol Chem 278:34418-34426
-
(2003)
J Biol Chem
, vol.278
, pp. 34418-34426
-
-
Ge, L.1
Ly, Y.2
Hollenberg, M.3
DeFea, K.4
-
180
-
-
77951892842
-
The cargo receptor p24A facilitates calcium sensing receptor maturation and stabilization in the early secretory pathway
-
Stepanchick A, Breitwieser GE 2010 The cargo receptor p24A facilitates calcium sensing receptor maturation and stabilization in the early secretory pathway. Biochem Biophys Res Commun 395: 136-140
-
(2010)
Biochem Biophys Res Commun
, vol.395
, pp. 136-140
-
-
Stepanchick, A.1
Breitwieser, G.E.2
-
181
-
-
78650014998
-
Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif
-
Stepanchick A, McKenna J, McGovern O, Huang Y, Breitwieser GE 2010 Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif. Cell Physiol Biochem 25:363-374
-
(2010)
Cell Physiol Biochem
, vol.25
, pp. 363-374
-
-
Stepanchick, A.1
McKenna, J.2
McGovern, O.3
Huang, Y.4
Breitwieser, G.E.5
-
182
-
-
77953769770
-
Calcium-sensing receptor biosynthesis includes a contranslational conformational checkpoint and endoplasmic reticulum retention
-
Cavanaugh A, McKenna J, Stepanchick A, Breitwieser GE 2010 Calcium-sensing receptor biosynthesis includes a contranslational conformational checkpoint and endoplasmic reticulum retention. J Biol Chem 285:19854-19864
-
(2010)
J Biol Chem
, vol.285
, pp. 19854-19864
-
-
Cavanaugh, A.1
McKenna, J.2
Stepanchick, A.3
Breitwieser, G.E.4
-
183
-
-
33744958957
-
Calcium sensing receptor ubiquitination and degradation mediated by the E3 ubiq-uitin ligase dorfin
-
Huang Y, Niwa J, Sobue G, Breitwieser GE 2006 Calcium sensing receptor ubiquitination and degradation mediated by the E3 ubiq-uitin ligase dorfin. J Biol Chem 281:11610-11617
-
(2006)
J Biol Chem
, vol.281
, pp. 11610-11617
-
-
Huang, Y.1
Niwa, J.2
Sobue, G.3
Breitwieser, G.E.4
-
184
-
-
81855173512
-
Agonist-driven maturation and plasma membrane insertion of calcium-sensing receptors dynamically controls signal amplitude
-
Grant MP, Stepanchick A, Cavanaugh A, Breitwieser GE 2011 Agonist-driven maturation and plasma membrane insertion of calcium-sensing receptors dynamically controls signal amplitude. Sci Signal 4:ra78
-
(2011)
Sci Signal
, vol.4
-
-
Grant, M.P.1
Stepanchick, A.2
Cavanaugh, A.3
Breitwieser, G.E.4
-
185
-
-
84856710439
-
A large putative PEST-like sequence motif at the carboxyl-tail of the human calcium receptor directs lysosomal degradation and regulates cell surface receptor level
-
Zhuang X, Northup JK, Ray K 2012 A large putative PEST-like sequence motif at the carboxyl-tail of the human calcium receptor directs lysosomal degradation and regulates cell surface receptor level. J Biol Chem 287:4165-4176
-
(2012)
J Biol Chem
, vol.287
, pp. 4165-4176
-
-
Zhuang, X.1
Northup, J.K.2
Ray, K.3
-
186
-
-
17744364491
-
A large homozygous or heterozygous in-frame deletion within the calcium-sensing receptor's carboxylterminal cytoplasmic tail that causes autosomal dominant hypocalcemia
-
Lienhardt A, Garabedian M, Bai M, Sinding C, Zhang Z, Lagarde JP, Boulesteix J, Rigaud M, Brown EM, Kottler ML 2000 A large homozygous or heterozygous in-frame deletion within the calcium-sensing receptor's carboxylterminal cytoplasmic tail that causes autosomal dominant hypocalcemia. J Clin Endocrinol Metab 85:1695-1702
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 1695-1702
-
-
Lienhardt, A.1
Garabedian, M.2
Bai, M.3
Sinding, C.4
Zhang, Z.5
Lagarde, J.P.6
Boulesteix, J.7
Rigaud, M.8
Brown, E.M.9
Kottler, M.L.10
-
187
-
-
34250836803
-
Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism
-
Reyes-Ibarra AP, Garcia-Regalado A, Ramirez-Rangel I, Esparza-Silva AL, Valadez-Sanchez M, Vazquez-Prado J, Reyes-Cruz G 2007 Calcium-sensing receptor endocytosis links extracellular calcium signaling to parathyroid hormone-related peptide secretion via a Rab11a-dependent and AMSH-sensitive mechanism. Mol Endocrinol 21:1394-1407
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1394-1407
-
-
Reyes-Ibarra, A.P.1
Garcia-Regalado, A.2
Ramirez-Rangel, I.3
Esparza-Silva, A.L.4
Valadez-Sanchez, M.5
Vazquez-Prado, J.6
Reyes-Cruz, G.7
-
188
-
-
66049118120
-
Direct upregulation of parathyroid calcium-sensing receptor and vitamin D receptor by calcimi-metics in uremic rats
-
Mendoza FJ, Lopez I, Canalejo R, Almaden Y, Martin D, Aguil-era-Tejero E, Rodriguez M 2009 Direct upregulation of parathyroid calcium-sensing receptor and vitamin D receptor by calcimi-metics in uremic rats. Am J Physiol Renal Physiol 296:F605-F613
-
(2009)
Am J Physiol Renal Physiol
, vol.296
-
-
Mendoza, F.J.1
Lopez, I.2
Canalejo, R.3
Almaden, Y.4
Martin, D.5
Aguil-era-Tejero, E.6
Rodriguez, M.7
-
189
-
-
16644401755
-
Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency
-
Mizobuchi M, Hatamura I, Ogata H, Saji F, Uda S, Shiizaki K, Sakaguchi T, Negi S, Kinugasa E, Koshikawa S, Akizawa T 2004 Calcimimetic compound upregulates decreased calcium-sensing receptor expression level in parathyroid glands of rats with chronic renal insufficiency. J Am Soc Nephrol 15:2579-2587
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2579-2587
-
-
Mizobuchi, M.1
Hatamura, I.2
Ogata, H.3
Saji, F.4
Uda, S.5
Shiizaki, K.6
Sakaguchi, T.7
Negi, S.8
Kinugasa, E.9
Koshikawa, S.10
Akizawa, T.11
-
190
-
-
33747120931
-
Biosynthesis and trafficking of seven transmembrane receptor signaling complexes
-
Dupre DJ, Hebert TE 2006 Biosynthesis and trafficking of seven transmembrane receptor signaling complexes. Cell Signal 18: 1549-1559
-
(2006)
Cell Signal
, vol.18
, pp. 1549-1559
-
-
Dupre, D.J.1
Hebert, T.E.2
-
191
-
-
33845926059
-
Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking
-
Dupre DJ, Robitaille M, Ethier N, Villeneuve LR, Mamarbachi AM, Hebert TE 2006 Seven transmembrane receptor core signaling complexes are assembled prior to plasma membrane trafficking. J Biol Chem 281:34561-34573
-
(2006)
J Biol Chem
, vol.281
, pp. 34561-34573
-
-
Dupre, D.J.1
Robitaille, M.2
Ethier, N.3
Villeneuve, L.R.4
Mamarbachi, A.M.5
Hebert, T.E.6
-
192
-
-
33846234212
-
Signalling complexes associated with adenylyl cyclase are assembled during their biosynthesis
-
Dupre DJ, Baragli A, Rebois RV, Ethier N, Hebert TE 2007 Signalling complexes associated with adenylyl cyclase are assembled during their biosynthesis. Cell Signal 19:481-489
-
(2007)
Cell Signal
, vol.19
, pp. 481-489
-
-
Dupre, D.J.1
Baragli, A.2
Rebois, R.V.3
Ethier, N.4
Hebert, T.E.5
-
193
-
-
59849092871
-
Multiple Ca2+-binding sites in the extracellular domain of the Ca2+-sensing receptor corresponding to cooperative Ca2+ response
-
Huang Y, Zhou Y, Castiblanco A, Yang W, Brown EM, Yang JJ 2009 Multiple Ca2+-binding sites in the extracellular domain of the Ca2+-sensing receptor corresponding to cooperative Ca2+ response. Biochemistry 48:388-398
-
(2009)
Biochemistry
, vol.48
, pp. 388-398
-
-
Huang, Y.1
Zhou, Y.2
Castiblanco, A.3
Yang, W.4
Brown, E.M.5
Yang, J.J.6
-
194
-
-
84861734350
-
Identification of 70 calcium-sensing receptor mutations in hyper-and hypo-calcemic pa tients: Evidence for clustering of extracellular domain mutations at calcium-binding sites
-
Hannan FM, Nesbit MA, Zhang C, Cranston T, Curley AJ, Harding B, Fratter C, Rust N, Christie PT, Turner JJ, Lemos MC, Bowl MR, Bouillon R, Brain C, Bridges N, Burren C, Connell JM, Jung H, Marks E, McCredie D, Mughal Z, Rodda C, Tollefsen S, Brown EM, Yang JJ, Thakker RV 2012 Identification of 70 calcium-sensing receptor mutations in hyper-and hypo-calcemic pa tients: evidence for clustering of extracellular domain mutations at calcium-binding sites. Hum Mol Genet 21:2768-2778
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2768-2778
-
-
Hannan, F.M.1
Nesbit, M.A.2
Zhang, C.3
Cranston, T.4
Curley, A.J.5
Harding, B.6
Fratter, C.7
Rust, N.8
Christie, P.T.9
Turner, J.J.10
Lemos, M.C.11
Bowl, M.R.12
Bouillon, R.13
Brain, C.14
Bridges, N.15
Burren, C.16
Connell, J.M.17
Jung, H.18
Marks, E.19
McCredie, D.20
Mughal, Z.21
Rodda, C.22
Tollefsen, S.23
Brown, E.M.24
Yang, J.J.25
Thakker, R.V.26
more..
-
195
-
-
0035860795
-
Interaction of the calcium-sensing receptor with filamin, a potential scaffolding protein
-
Awata H, Huang C, Handlogten ME, Miller RT 2001 Interaction of the calcium-sensing receptor with filamin, a potential scaffolding protein. J Biol Chem 276:34871-34879
-
(2001)
J Biol Chem
, vol.276
, pp. 34871-34879
-
-
Awata, H.1
Huang, C.2
Handlogten, M.E.3
Miller, R.T.4
-
196
-
-
0035860748
-
Filamin A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase
-
Hjalm G, MacLeod RJ, Kifor O, Chattopadhyay N, Brown EM 2001 Filamin A binds to the carboxyl-terminal tail of the calcium-sensing receptor, an interaction that participates in CaR-mediated activation of mitogen-activated protein kinase. J Biol Chem 276: 34880-34887
-
(2001)
J Biol Chem
, vol.276
, pp. 34880-34887
-
-
Hjalm, G.1
MacLeod, R.J.2
Kifor, O.3
Chattopadhyay, N.4
Brown, E.M.5
-
197
-
-
27844496106
-
Receptor-activity-modifying proteins are required for forward trafficking of the calcium-sensing receptor to the plasma membrane
-
Bouschet T, Martin S, Henley JM 2005 Receptor-activity-modifying proteins are required for forward trafficking of the calcium-sensing receptor to the plasma membrane. J Cell Sci 118:47094720
-
(2005)
J Cell Sci
, vol.118
, pp. 47094720
-
-
Bouschet, T.1
Martin, S.2
Henley, J.M.3
-
198
-
-
80052645238
-
Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling
-
Magno AL, Ingley E, Brown SJ, Conigrave AD, Ratajczak T, Ward BK 2011 Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling. Biochem Biophys Res Commun 412:584-589
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 584-589
-
-
Magno, A.L.1
Ingley, E.2
Brown, S.J.3
Conigrave, A.D.4
Ratajczak, T.5
Ward, B.K.6
-
199
-
-
81755189015
-
Calcium-sensing receptor modulates cell adhesion and migration via integrins
-
Tharmalingam S, Daulat AM, Antflick JE, Ahmed SM, Nemeth EF, Angers S, Conigrave AD, Hampson DR 2011 Calcium-sensing receptor modulates cell adhesion and migration via integrins. J Biol Chem 286:40922-40933
-
(2011)
J Biol Chem
, vol.286
, pp. 40922-40933
-
-
Tharmalingam, S.1
Daulat, A.M.2
Antflick, J.E.3
Ahmed, S.M.4
Nemeth, E.F.5
Angers, S.6
Conigrave, A.D.7
Hampson, D.R.8
-
201
-
-
79960925570
-
Checks and balances: Interplay of RTKs and PTPs in cancer progression
-
Sastry SK, Elferink LA 2011 Checks and balances: interplay of RTKs and PTPs in cancer progression. Biochem Pharmacol 82: 435-440
-
(2011)
Biochem Pharmacol
, vol.82
, pp. 435-440
-
-
Sastry, S.K.1
Elferink, L.A.2
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