Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor

Current Pharmaceutical Biotechnology

Volumn 10, Issue 3, 2009, Pages 270-281

  Brennan, Sarah C ^a   Conigrave, Arthur D ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CALCITONIN; CALCIUM; CALCIUM SENSING RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PARATHYROID HORMONE; PARATHYROID HORMONE RELATED PROTEIN; PHENYLALKYLAMINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL KINASE; PHOSPHOLIPASE A2; PHOSPHOLIPASE C; PHOSPHOLIPASE D; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; STRESS ACTIVATED PROTEIN KINASE;

CALCIUM METABOLISM; CALCIUM MOBILIZATION; CALCIUM TRANSPORT; CELL FUNCTION; CELL MATURATION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; EXTRACELLULAR MATRIX; HUMAN; KIDNEY COLLECTING TUBULE; KIDNEY CORTEX; LIGAND BINDING; LIPID MEMBRANE; MOLECULAR CLONING; NONHUMAN; PARATHYROID HORMONE RELEASE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; SIGNAL TRANSDUCTION; STOMACH ACID SECRETION; WATER TRANSPORT;

ANIMALS; CALCIUM SIGNALING; CELL PROLIFERATION; CELL SURVIVAL; EPITHELIUM; EXTRACELLULAR SPACE; HUMANS; LIPID METABOLISM; NUTRITIONAL PHYSIOLOGICAL PHENOMENA; PEPTIDE HORMONES; PROTEIN KINASES; RECEPTORS, CALCIUM-SENSING; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 65949090315     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920109787847484     Document Type: Review

References (166)

1. Pierce, K.L.; Premont, R.T. and Lefkowitz, R.J. (2002) Nature Rev. Mol. Cell Biol., 3, 639-650.
2. Gurevich, V.V. and Gurevich, E.V. (2008) Trends Neurosci., 31, 74-81.
3. Kobilka, B.K. (2007) Biochim. Biophys. Acta., 1768, 794-807.
4. O'Hara, P.J.; Sheppard, P.O.; Thogersen, H.; Venezia, D.; Haldeman, B.A.; McGrane, V.; Houamed, K.M.; Thomsen, C.; Gilbert, T.L. and Mulvihill, E.R. (1993) Neuron, 11, 41-52.
5. Conklin, B.R. and Bourne, H.R. (1994) Nature, 367, 22.
6. Kaupmann, K.; Huggel, K.; Heid, J.; Flor, P.J.; Bischoff, S.; Mickel, S.J.; McMaster, G.; Angst, C.; Bittiger, H.; Froestl, W. and Bettler, B. (1997) Nature, 386, 239-246.
7. Brown, E.M. and MacLeod, R.J. (2001) Physiol. Rev., 81, 239-297.
8. Matsunami, H. and Buck, L.B. (1997) Cell, 90, 775-784.
9. Wellendorph, P.; Hansen, K.B.; Balsgaard, A.; Greenwood, J.R.; Egebjerg, J. and Brauner-Osborne, H. (2005) Mol. Pharmacol., 67, 589-597.
10. Kuang, D.; Yao, Y.; Lam, J.; Tsushima, R.G. and Hampson, D.R. (2005) J. Neurochem., 93, 383-391.
11. Wellendorph, P. and Brauner-Osborne, H. (2004) Gene, 335, 37-46.
12. Speca, D.; Lin, D.; Sorensen, P.; Isacoff, E.; Ngai, J. and Dittman, A. (1999) Neuron, 23, 487-498.
13. Cao, Y.; Oh, B.C. and Stryer, L. (1998) Proc. Natl. Acad. Sci. USA, 95, 11987-11992.
14. Conigrave, A.D. and Hampson, D.R. (2006) Trends Endocrinol. Metab., 17, 398-407.
15. Hu, J.; Hauache, O. and Spiegel, A.M. (2000) J. Biol. Chem., 275, 6382-16389.
16. Hu, J. and Spiegel, A.M. (2007) J. Cell Mol. Med., 11, 908-922.
17. Bai, M.; Trivedi, S. and Brown, E.M. (1998) J. Biol. Chem., 273, 23605-23610.
18. Jones, K.A.; Borowsky, B.; Tamm, J.A.; Craig, D.A.; Durkin, M.M.; Dai, M.; Yao, W.J.; Johnson, M.; Gunwaldsen, C.; Huang, L.Y.; Tang, C.; Shen, Q.; Salon, J.A.; Morse, K.; Laz, T.; Smith, K.E.; Nagarathnam, D.; Noble, S.A.; Branchek, T.A. and Gerald, C. (1998) Nature, 396, 674-679.
19. Kaupmann, K.; Malitschek, B.; Schuler, V.; Heid, J.; Froestl, W.; Beck, P.; Mosbacher, J.; Bischoff, S.; Kulik, A.; Shigemoto, R.; Karschin, A. and Bettler, B. (1998) Nature, 396, 683-687.
20. White, J.H.; Wise, A.; Main, M.J.; Green, A.; Fraser, N.J.; Disney, G.H.; Barnes, A.A.; Emson, P.; Foord, S.M. and Marshall, F.H. (1998) Nature, 396, 679-682.
21. Jiang, Y.; Minet, E.; Zhang, Z.; Silver, P.A. and Bai, M. (2004) J. Biol. Chem., 279, 14147-14156.
22. Ray, K.; Hauschild, B.C.; Steinbach, P.J.; Goldsmith, P.K.; Hauache, O. and Spiegel, A.M. (1999) J. Biol. Chem., 274, 27642-27650.
23. Bai, M.; Trivedi, S.; Kifor, O.; Quinn, S.J. and Brown, E.M. (1999) Proc. Natl. Acad. Sci. USA, 96, 2834-2839.
24. Bouschet, T.; Martin, S. and Henley, J.M. (2008) Trends Pharmacol. Sci., 29, 633-639.
25. Parameswaran, N. and Spielman, W.S. (2006) Trends Biochem. Sci., 31, 631-638.
26. Huang, C. and Miller, R.T. (2007) J. Cell Mol. Med., 11, 923-934.
27. Bouschet, T.; Martin, S. and Henley, J.M. (2005) J. Cell Sci., 118, 4709-4720.
28. Brown, E.M.; Gamba, G.; Riccardi, D.; Lombardi, M.; Butters, R.; Kifor, O.; Sun, A.; Hediger, M.A.; Lytton, J. and Hebert, S.C. (1993) Nature, 366, 575-580.
29. Brown, E.M. (2007) Nat. Clin. Pract. Endocrinol. Metab., 3, 122-133.
30. Silve, C.; Petrel, C.; Leroy, C.; Bruel, H.; Mallet, E.; Rognan, D. and Ruat, M. (2005) J. Biol. Chem., 280, 37917-37923.
31. Huang, Y.; Zhou, Y.; Yang, W.; Butters, R.; Lee, H-W.; Li, S.; Castiblanco, A.; Brown, E.M. and Yang, J.J. (2007) J. Biol. Chem., 282, 19000-19010.
32. Mun, H.C.; Franks, A.H.; Culverston, E.L.; Krapcho, K.; Nemeth, E.F. and Conigrave, A.D. (2004) J. Biol. Chem., 279, 51739-51744.
33. Miedlich, S.U.; Gama, L.; Seuwen, K.; Wolf, R.M. and Breitwieser, G.E. (2004) J. Biol. Chem., 279, 7254-7263.
34. Hauache, O.M.; Hu, J.; Ray, K.; Xie, R.; Jacobson, K.A. and Spiegel, A.M. (2000) Endocrinology, 141, 4156-4163.
35. Conigrave, A.D. and Brown, E.M. (2006) Am. J. Physiol., 291, G753-G761.
36. Quinn, S.J.; Ye, C.P.; Diaz, R.; Kifor, O.; Bai, M.; Vassilev, P. and Brown, E. (1997) Am. J. Physiol., 273, C1315-1323.
37. Nemeth, E.F. and Scarpa, A. (1987) Spermine evokes the rapid mobilization of cellular Ca2+ in parathyroid cells. In: Norman AW, Vanaman TC, Means AR, Eds. Calcium-binding proteins in health and disease. San Diego, Academic Press; 33-35.
38. Ward, D.T.; Maldonado-Perez, D.; Hollins, L. and Riccardi, D. (2005) J. Am. Soc. Nephrol., 16, 1236-1244.
39. Gibbons, C.E.; Maldonado-Pérez, D.; Shah, A.N.; Riccardi, D. and Ward, D.T. (2008) Biochim. Biophys. Acta., 1782, 188-195.
40. McLarnon, S.; Holden, D.; Ward, D.; Jones, M.; Elliott, A. and Riccardi, D. (2002) Biochem. Biophys. Res. Commun., 297, 71-77.
41. Quinn, S.J.; Kifor, O.; Trivedi, S.; Diaz, R.; Vassilev, P. and Brown, E.M. (1998) J. Biol. Chem., 273, 19579-19586.
42. Quinn, S.J.; Bai, M. and Brown, E.M. (2004) J. Biol. Chem., 279, 37241-37249.
43. Ward, D.T. (2004) Cell Calcium, 35, 217-228.
44. Chang, W.; Chen, T.H.; Pratt, S. and Shoback, D. (2000) J. Biol. Chem., 275, 19955-19963.
45. Chang, W.; Pratt, S.; Chen, T.H.; Bourguignon, L. and Shoback, D. (2001) J. Biol. Chem., 276, 44129-44136.
46. Jiang, Y.F.; Zhang, Z.; Kifor, O.; Lane, C.R.; Quinn, S.J. and Bai, M. (2002) J. Biol. Chem., 277, 50543-50549.
47. Bai, M.; Trivedi, S.; Lane, C.R.; Yang, Y.; Quinn, S.J. and Brown, E.M. (1998) J. Biol. Chem., 273, 21267-21275.
48. Hjalm, G.; MacLeod, R.J.; Kifor, O.; Chattopadhyay, N. and Brown, E.M. (2001) J. Biol. Chem., 276, 34880-34887.
49. Awata, H.; Huang, C.; Handlogten, M.E. and Miller, R.T. (2001) J. Biol. Chem., 276, 34871-34879.
50. Huang, Y.; Niwa, J.; Sobue, G. and Breitwieser, G.E. (2006) J. Biol. Chem., 281, 11610-11617.
51. Herrera-Vigenor, F.; Hernández-García, R.; Valadez-Sánchez, M.; Vázquez-Prado, J. and Reyes-Cruz, G. (2006) Biochem. Biophys. Res. Commun., 347, 924-930.
52. Huang, C.; Wu, Z.; Hujer, K.M. and Miller, R.T. (2006) FEBS Lett., 580, 1795-1800.
53. Kifor, O.; Diaz, R.; Butters, R.; Kifor, I. and Brown, E.M. (1998) J. Biol. Chem., 273, 21708-21713.
54. Stahlhut, M. and Deurs, B.V. (2000) Mol. Biol. Cell, 11, 325-337.
55. Pi, M.; Spurney, R.F.; Tu, Q.; Hinson, T. and Quarles, L.D. (2002) Endocrinology, 143, 3830-3838.
56. Huang, C.; Hujer, K.M.; Wu, Z. and Miller, R.T. (2004) Am. J. Physiol. Cell Physiol., 286, C22-C30.
57. Mamillapalli, R.;VanHouten, J.; Zawalich, W. and Wysolmerski, J. (2008) J. Biol. Chem., 283, 24435-24447.
58. Hofer, A.M. and Brown, E.M. (2003) Nat. Rev. Mol. Cell Biol., 4, 530-538.
59. Yamaguchi, T. (2008) J. Bone Miner. Metab., 26, 301-311.
60. Wettschureck, N.; Lee, E.; Libutti, S.K.; Offermanns, S.; Robey, P.G. and Spiegel, A.M. (2007) Mol. Endocrinol., 21, 74-280.
61. Ho, C.; Conner, D.A.; Pollak, M.R.; Ladd, D.J.; Kifor, O.; Warren, H.B.; Brown, E.M.; Seidman, J.G. and Seidman, C.E. (1995) Nat. Genet., 11, 389-394.
62. Ray, K.; Fan, G.F.; Goldsmith, P.K. and Spiegel, A.M. (1997) J. Biol. Chem., 272, 31355-31361.
63. Brown, E.M. and MacLeod, R.J. (2001) Physiol. Rev., 81, 239-297.
64. Chen, C.J.; Barnett, J.V.; Congo, D.A. and Brown, E.M. (1989) Endocrinology, 124, 233-239.
65. Chang, W, Pratt, S.; Chen, T.H.; Nemeth, E.; Huang, Z. and Shoback, D. (1998) J. Bone Miner. Res., 13, 570-580.
66. Firsov, D.; Aarab, L.; Mandon, B.; Siaume-Perez, S.; de Rouffignac, C. and Chabardes, D. (1995) Pflugers Arch., 429, 636-646.
67. Ferreira, M.C.dJ.; Héliès-Toussaint, C.; Imbert-Teboul, M.; Bailly, C.; Verbavatz, J.M.; Bellanger, A.C. and Chabardès, D. (1998) J. Biol. Chem., 15192-15202.
68. Huang, C.; Hujer, K.M.; Wu, Z. and Miller, R.T. (2004) Am. J. Physiol. Cell Physiol., 286, C22-30.
69. Rey, O.; Young, S.H.; Yuan, J.; Slice, L. and Rozengurt, E. (2005) J. Biol. Chem., 280, 22875-22882.
70. Bhattacharya, M.; Babwah, A.V. and Ferguson, S.S. (2004) Biochem. Soc. Trans., 32, 1040-1044.
71. Gohla, A.; Offermanns, S.; Wilkie, T.M. and Schultz, G. (1999) J. Biol. Chem., 274, 17901-17907.
72. Davies, S.L.; Gibbons, C.E.; Vizard, T. and Ward, D.T. (2006) Am. J. Physiol. Cell Physiol., 290, 1543-1551.
73. Huang, C.; Handlogten, M.E. and Miller, R.T. (2002) J. Biol. Chem., 277, 20293-20300.
74. Bouschet, T.; Martin, S.; Kanamarlapudi, V.; Mundell, S. and Henley, J.M. (2007) J. Cell Sci., 120, 2489-2497.
75. Hobson, S.A.; Wright, J.; Lee, F.; McNeil, S.E.; Bilderback, T. and Rodland, K.D. (2003) Mol. Cell Endocrinol., 200, 189-198.
76. Hobson, S.A.; McNeil, S.E.; Lee, F. and Rodland, K.D. (2000) Exp. Cell Res., 258, 1-11.
77. Kifor, O.; MacLeod, R.J.; Diaz, R.; Bai, M.; Yamaguchi, T.; Yao, T.; Kifor, I. and Brown, E.M. (2001) Am. J. Physiol. Renal Physiol., 280, F291-F302.
78. Crespo, P.; Xu, N.; Simonds, W.F. and Gutkind, J.S. (1994) Nature, 369, 418-420.
79. MacLeod, R.J.; Yano, S.; Chattopadhyay, N. and Brown, E.M. (2004) Biochem. Biophys. Res. Commun, 320, 455-460.
80. Reyes-Ibarra, A.P.; García-Regalado, A.; Ramírez-Range, I.; Esparza-Silva, A.L.; Valadez-Sánchez, M.; Vázquez-Prado, J. and Reyes-Cruz, G. (2007) Mol. Endocrinol., 21, 1394-1407.
81. Bai, M.; Quinn, S.; Trivedi, S.; Kifor, O.; Pearce, S.H.S.; Pollak, M.R.; Krapcho, K.; Hebert, S.C. and Brown, E.M. (1996) J. Biol. Chem., 271, 19537-19545.
82. Nemeth, E.F. and Scarpa, A. (1987) J. Biol. Chem., 262, 5188-5196.
83. Brown, E.M.; Enyedi, P.; Leboff, M.; Rotberg, J.; Preston, J. and Chen, C. (1987) FEBS Lett., 218, 113-118.
84. Cheng, I.; Qureshi, I.; Chattopadhyay, N.; Qureshi, A.; Butters, R.R.; Hall, A.E.; Cima, R.R.; Rogers, K.V.; Hebert, S.C.; Geibel, J.P.; Brown, E.M. and Soybel, D.I. (1999) Gastroenterology, 116, 118-126.
85. Arthur, J.M.; Collinsworth, G.P.; Gettys, T.W.; Quarles, L.D. and Raymond, J.R. (1997) Am. J. Physiol., 273, F129-F135.
86. Ogata, S.; Kubota, Y.; Satoh, S.; Ito, S.; Takeuchi, H.; Ashizuka, M. and Shirasuna, K. (2006) Biochem. Biophys. Res. Commun., 351, 808-814.
87. Blankenship, K.A.; Williams, J.J.; Lawrence, M.S.; McLeish, K.R.; Dean, W.L. and Arthur, J.M. (2001) Am. J. Physiol. Renal. Physiol., 280, F815-F822.
88. Godwin, S.L. and Soltoff, S.P. (1997) J. Biol. Chem., 272, 11307-11312.
89. Kifor, O.; Diaz, R.; Butters, R. and Brown, E.M. (1997) J. Bone Miner. Res., 12, 715-725.
90. Wang, W.; Lu, M.; Balazy, M. and Hebert, S.C. (1997) Am. J. Physiol., 273, F421-429.
91. Handlogten, M.E.; Shiraishi, N.; Awata, H.; Huang, C. and Miller, R.T. (2001) Am. J. Physiol. Renal Physiol., 279, F1083-F1091.
92. Bourdeau, A.; Souberbielle, J.C.; Bonnet, P.; Herviaux, P.; Sachs, C. and Lieberherr, M. (1992) Endocrinology, 130, 1339-1344.
93. Tfelt-Hansen, J.; Chattopadhyay, N.; Yano, S.; Kanuparthi, D.; Rooney, P.; Schwarz, P. and Brown, E.M. (2004) Endocrinology, 145, 1211-1217.
94. Bilderback, T.R.; Lee, F.; Auersperg, N. and Rodland, K.D. (2002) Am. J. Physiol. Cell Physiol., 283, C282-C288.
95. Tu, C.L.; Chang, W.; Xie, Z. and Bikle, D.D. (2008) J. Biol. Chem., 283, 3519-3528.
96. Liu, K.P.; Russo, A.F.; Hsiung, S.C.; Adlersberg, M.; Franke, T.F.; Gershon, M.D. and Tamir, H. (2003) J. Neurosci., 23, 2049-2057.
97. Ward, D.T. (2004) Cell Calcium, 35, 217-228.
98. Breitwieser, G.E. (2006) Curr. Top. Dev. Biol., 73, 85-114.
99. Lorenz, S.; Frenzel, R.; Paschke, R.; Breitwieser, G.E. and Miedlich, S.U. (2007) Endocrinology, 148, 2398-2404.
100. Pi, M.; Oakley, R.H.; Gesty-Palmer, D.; Cruickshank, R.D.; Spurney, R.F.; Luttrell, L.M. and Quarles, L.D. (2005) Mol. Endocrinol., 19, 1078-1087.
101. Steinberg, S.F. (2008) Physiol. Rev., 88, 1341-1378.
102. Sakwe, A.M.; Larsson, M. and Rask, L. (2004) Exp. Cell Res., 297, 560-573.
103. Liu, K.; Hsiung, S.; Adlersberg, M.; Sacktor, T.; Gershon, M.D. and Tamir, H. (2000) J. Neurosci., 20, 1365-1373.
104. Davies, S.L.; Ozawa, A.; McCormick, W.D.; Dvorak, M.M. and Ward, D.T. (2007) J. Biol. Chem., 282, 15048-15056.
105. Johnson, G.L. and Lapadat, R. (2002) Science, 298, 1911-1912.
106. Lee, H.J.; Mun, H.C.; Lewis, N.C.; Crouch, M.F.; Culverston, E.L.; Mason, R.S. and Conigrave, A.D. (2007) Biochem. J., 404, 141-149.
107. MacLeod, R.J.; Chattopadhyay, N. and Brown, E.M. (2003) Am. J. Physiol. Endocrinol. Metab., 284, E435-442.
108. Corbetta, S.; Lania, A.; Filopanti, M.; Vicentini, L.; Ballare, E. and Spada, A. (2002) J. Clin. Endocrinol. Metab., 87, 2201-2205.
109. Yamaguchi, T.; Chattopadhyay, N.; Kifor, O.; Sanders, J.L. and Brown, E.M. (2000) Biochem. Biophys. Res. Commun., 279, 363-368.
110. Arthur, J.M.; Lawrence, M.S.; Payne, C.R.; Rane, M.J. and McLeish, K.R. (2000) Biochem. Biophys. Res. Commun., 275, 538-541.
111. Daub, H.; Weiss, F.U.; Wallasch, C. and Ullrich, A. (1996) Nature, 379, 557-560.
112. Luttrell, L.M.; Daaka, Y. and Lefkowitz, R.J. (1999) Curr. Opin. Cell Biol., 11, 177-183.
113. MacLeod, R.J.; Yano, S.; Chattopadhyay, N. and Brown, E.M. (2004) Biochem. Biophys. Res. Commun., 320, 455-460.
114. Yano, S.; Macleod, R.J.; Chattopadhyay, N.; Tfelt-Hansen, J.; Kifor, O.; Butters, R.R. and Brown, E.M. (2004) Bone, 35, 664-672.
115. Breitwieser, G.E. and Gama, L. (2001) Am. J. Physiol. Cell. Physiol., 280, C1412-1421.
116. Miki, H.; Maercklein, P.B. and Fitzpatrick, L.A. (1995) Endocrinology, 136, 2954-2959.
117. Ridefelt, P.; Björklund, E.; Akerström, G.; Olsson, M.J.; Rastad, J. and Gylfe, E. (1995) Biochem. Biophys. Res. Commun., 215, 903-909.
118. Breitwieser, G.E. (2006) Curr. Top. Dev. Biol., 73, 85-114.
119. Miedlich, S.; Gama, L. and Breitwieser, G.E. (2002) J. Biol. Chem., 277, 49691-49699.
120. Breitwieser, G.E. and Gama, L. (2001) Am. J. Physiol., 280, C1412-C1421.
121. Berridge, M.J.; Bootman, M.D. and Roderick, H.L. (2003) Nat. Rev. Mol. Cell Biol., 4, 517-529.
122. Rey, O.; Young, S.H.; Papazyan, R.; Shapiro, M.S. and Rozengurt, E. (2006) J. Biol. Chem., 281, 38730-38737.
123. Chang, W.; Tu, C.; Chen, T.H.; Bikle, D. and Shoback, D. (2008) Signalling, 1, ra1.
124. Corbetta, S.; Lania, A.; Filopanti, M.; Vicentini, L.; Ballare, E. and Spada, A. (2002) J. Clin. Endocrinol. Metab., 87, 2201-2205.
125. Bourdeau, A.; Moutahir, M.; Souberbielle, J.C.; Bonnet, P.; Herviaux, P.; Sachs, C. and Lieberherr, M. (1994) Endocrinology, 135, 1109-1112.
126. Quinn, S.J.; Kifor, O.; Kifor, I.; Butters, R.R. and Brown, E.M. (2007) Biochem. Biophys. Res. Commun., 354, 8-13.
127. Lu, M.; Forsberg, L.; Jühlin, C.C.; Vukojevic, V.; Larsson, C.; Conigrave, A.D.; Delbridge, L.W.; Gill, A.; Farnebo, L-O. and Branstrom, R. (2008) Mol. Cell Endocrinol., 287, 72-80.
128. Davey, R.A.; Turner, A.G.; McManus, J.F.; Chiu, W.S.; Tjahyono, F.; Moore, A.J.; Atkins, G.J.; Anderson, P.H.; Ma, C.; Glatt, V.; MacLean, H.E.; Vincent, C.; Bouxsein, M.; Morris, H.A.; Findlay, D.M. and Zajac, J.D. (2008) J. Bone Miner. Res., 23, 1182-1193.
129. Fajtova, V.T.; Quinn, S.J. and Brown, E.M. (1991) Am. J. Physiol., 261, E151-E158.
130. Muff, R.; Nemeth, E.F.; Haller-Brem, S. and Fischer, J.A. (1988) Arch. Biochem. Biophys., 265, 128-135.
131. Garrett, J.E.; Tamir, H.; Kifor, O.; Simin, R.T.; Rogers, K.V.; Mithal, A.; Gagel, R.F. and Brown, E.M. (1995) Endocrinol., 136, 5202-5211.
132. Fox, J.; Lowe, S.H.; Petty, B.A. and Nemeth, E.F. (1999) J. Pharmacol. Exp. Ther., 290, 473-479.
133. VanHouten, J.; Dann, P.; McGeoh, G.; Brown, E.M.; Krapcho, K.; Neville, M. and Wysolmerski, J.J. (2004) J. Clin. Invest., 113, 598-608.
134. Ardeshirpour, L.; Dann, P.; Pollak, M.; Wysolmerski, J. and Van-Houten, J. (2006) Bone, 38, 787-793.
135. Miao, D.; He, B.; Jiang, Y.; Kobayashi, T.; Sorocéanu, M.A.; Zhao, J.; Su, H.; Tong, X.; Amizuka, N.; Gupta, A.; Genant, H.K.; Kronenberg, H.M.; Goltzman, D. and Karaplis, A.C. (2005) J. Clin. Invest., 115, 2322-2324.
136. Rankin, W.; Grill, V. and Martin, T.J. (1997) Cancer, 80, 1564-1571.
137. Chattopadhyay, N. (2006) Am. J. Physiol., 290, E761-E770.
138. Tfelt-Hansen, J.; MacLeod, R.J.; Chattopadhyay, N.; Yano, S.; Quinn, S.; Ren, X.; Terwilliger, E.F.; Schwarz, P. and Brown, E.M. (2003) Am. J. Physiol. Endocrinol. Metab., 285, E329-E337.
139. Gamba, G. and Friedman, P.A. (2008) Pflugers Arch Epub ahead of print.
140. Wang, W.H.; Lu, M. and Hebert, S.C. (1996) Am. J. Physiol., 271, C103-C111.
141. Motoyama, H.I. and Friedman, P.A. (2002) Am. J. Physiol. Renal Physiol., 283, F399-F406.
142. Desfleurs, E.; Wittner, M.; Pajaud, S.; Nitschke, R.; Rajerison, R.M. and Stefano, A.D. (1999) Pflügers Arch., 437, 716-723.
143. Valenti, G.; procina, G.; Tamma, G.; Carmosino, M. and Svelto, M. (2005) Endocrinology, 146, 5063-5070.
144. Valenti, G.; Laera, A.; Gouraud, S.; Pace, G.; Aceto, G.; Penza, R.; Selvaggi, F.P. and Svelto, M. (2002) Am. J. Physiol. Renal Physiol., 283, F895-F903.
145. Valenti, G.; Laera, A.; Pace, G.; Aceto, G.; Lospalluti, M.L.; Penza, R.; Selvaggi, F.P.; Chiozza, M.L. and Svelto, M. (2000) J. Am. Soc. Nephrol., 10, 1873-1881.
146. Sands, J.M.; Naruse, M.; Baum, M.; Jo, I.; Hebert, S.C.; Brown, E.M. and Harris, H.W. (1997) J. Clin. Invest., 99, 1399-1405.
147. Butters, R.R.; Chattopadhyay, N.; Nielsen, P.; Smith, C.P.; Mithal, A.; Kifor, O.; Bai, M.; Quinn, S.; Goldsmith, P.; Hurwitz, S.; Krapcho, K.; Busby, J. and Brown, E.M. (1997) J. Bone Miner. Res., 12, 568-579.
148. Marx, S.J.; Attie, M.F.; Stock, J.L.; Spiegel, A.M. and Mal, M.A. (1981) J. Clin. Endocrinol. Metab., 52, 736-740.
149. Pearce, S.H.; Williamson, C.; Kifor, O.; Bai, M.; Coulthard, M.G.; Davies, M.; Lewis-Barned, N.; McCredie, D.; Powell, H.; Kendall-Taylor, P.; Brown, E.M. and Thakker, R.V. (1996) N. Engl. J. Med., 335, 1115-1122.
150. Sands, J.M.; Flores, F.X.; Kato, A.; Baum, M.A.; Brown, E.M.; Ward, D.T.; Hebert, S.C. and Harris, H.W. (1998) Am. J. Physiol., 274, F978-F985.
151. Procino, G.; Carmosino, M.; Tamma, G.; Gouraud, S.; Laera, A.; Riccardi, D.; Svelto, M. and Valenti, G. (2004) Kidney Int., 66, 2245-2255.
152. MacNeil, S.E.; Hobson, S.A.; Nipper, V. and Rodland, K.D. (1998) J. Biol. Chem., 273, 1114-1120.
153. Chang, W.; Tu, C.; Bajra, R.; Komuves, L.; Miller, S.; Strewler, G. and Shoback, D. (1999). Endocrinology, 140, 1911-1919.
154. Chang, W.; Tu, C.; Pratt, S.; Chen, T.H. and Shoback, D. (2002) Endocrinology, 143, 1467-1474.
155. Chang, W.; Tu, C.; Chen, T.H.; Komuves, L.; Oda, Y.; Pratt, S.A.; Miller, S. and Shoback, D. (1999) Endocrinology, 140, 5883-5893.
156. Yamaguchi, T.; Chattopadhyay, N.; Kifor, O. and Brown, E.M. (1998) Endocrinology, 139, 3561-3568.
157. Yamaguchi, T.; Chattopadhyay, N.; Kifor, O.; Ye, C.; Vassilev, P.M.; Sanders, J.L. and Brown, E.M. (2001) Am. J. Physiol., 280, C382-C393.
158. Dvorak, M.M.; Siddiqua, A.; Ward, D.T.; Carter, D.H.; Dallas, S.L.; Nemeth, E.F. and Riccardi, D. (2004) Proc. Natl. Acad. Sci. USA, 101, 5140-5145.
159. Adams, G.B.; Chabner, K.T.; Alley, I.R.; Olson, D.P.; Szczepiorkowski, Z.M.; Poznansky, M.C.; Kos, C.H.; Pollak; M.R.; Brown, E.M. and Scadden. D.T. (2006) Nature, 439, 599-603.
160. Tomlins, S.A.; Bolllinger, N.; Creim, J. and Rodland, K.D. (2005) Exp. Cell Res., 308, 439-445.
161. Brauner-Osborne, H.; Jensen, A.A.; Sheppard, P.O.; O'Hara, P. and Krogsgaard-Larsen, P. (1999) J. Biol. Chem., 274, 18382-18386.
162. Conigrave, A.D.; Quinn, S.J. and Brown, E.M. (2000) Proc. Natl. Acad. Sci. USA, 97, 4814-4819.
163. Conigrave, A.D.; Mun, H-C.; Delbridge, L.; Quinn, S.J.; Wilkinson, M. and Brown, E.M. (2004) J. Biol. Chem., 279, 38151-38159.
164. Ray, J.; Squires, P.; Curtis, S.; Meloche, M. and Buchan, A. (1997) J. Clin. Invest., 99, 2328-2333.
165. Buchan, A.; Squires, P.; Ring, M. and Meloche, R. (2001) Gastroenterology, 120, 1128-1139.
166. Tu, C.L.; Oda, Y.; Komuves, L. and Bikle, D.D. (2004) Cell Calcium, 35, 265-273.