Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca2+ receptor

Journal of Bone and Mineral Research

Volumn 22, Issue 4, 2007, Pages 601-608

  Hu, Jianxin ^a,c   Reyes Cruz, Guadalupe ^a   Goldsmith, Paul K ^a   Gantt, Nicole M ^b   Miller, Jeffery L ^b   Spiegel, Allen M ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Chimeric receptor; Extracellular domain; Human Ca2+ receptor; Monoclonal antibodies; Venus flytrap like domain

Indexed keywords

CALCIUM; CHIMERIC PROTEIN; CYSTEINE; EPITOPE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 1A8; MONOCLONAL ANTIBODY 5C8; MONOCLONAL ANTIBODY 7F8; PHOSPHATIDYLINOSITIDE; RECEPTOR; UNCLASSIFIED DRUG; CALCIUM SENSING RECEPTOR; HYBRID PROTEIN;

AMINO TERMINAL SEQUENCE; ANTIGEN BINDING; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; EXTRACELLULAR MATRIX; FLOW CYTOMETRY; HOMEOSTASIS; HUMAN; HUMAN CELL; HYDROLYSIS; HYPERPARATHYROIDISM; OSTEOPOROSIS; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PURIFICATION; RECEPTOR BINDING; RECEPTOR SENSITIVITY; REGULATORY MECHANISM; SEQUENCE HOMOLOGY; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; METABOLISM; MOUSE; MUTATION; PROTEIN TERTIARY STRUCTURE; PUFFER FISH;

ANIMALS; ANTIBODIES, MONOCLONAL; CALCIUM; CELL LINE; HUMANS; MICE; MODELS, MOLECULAR; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CALCIUM-SENSING; RECOMBINANT FUSION PROTEINS; TAKIFUGU;

EID: 34249718528     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.070111     Document Type: Article

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