메뉴 건너뛰기




Volumn 366, Issue 1, 2008, Pages 42-47

Complementary roles of the DRY motif and C-terminus tail of GPCRS for G protein coupling and β-arrestin interaction

Author keywords

arrestin; Dopamine D2 and D3 receptor; DRY motif; G protein

Indexed keywords

BETA ARRESTIN; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; VASOPRESSIN V2 RECEPTOR;

EID: 37349060671     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.11.055     Document Type: Article
Times cited : (41)

References (28)
  • 1
    • 0025352299 scopus 로고
    • Beta-arrestin: a protein that regulates beta-adrenergic receptor function
    • Lohse M.J., Benovic J.L., Codina J., Caron M.G., and Lefkowitz R.J. Beta-arrestin: a protein that regulates beta-adrenergic receptor function. Science 248 (1990) 1547-1550
    • (1990) Science , vol.248 , pp. 1547-1550
    • Lohse, M.J.1    Benovic, J.L.2    Codina, J.3    Caron, M.G.4    Lefkowitz, R.J.5
  • 3
    • 0030593035 scopus 로고    scopus 로고
    • Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
    • Ferguson S.S., Downey W.E., Colapietro A.M., Barak L.S., Menard L., and Caron M.G. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271 (1996) 363-366
    • (1996) Science , vol.271 , pp. 363-366
    • Ferguson, S.S.1    Downey, W.E.2    Colapietro, A.M.3    Barak, L.S.4    Menard, L.5    Caron, M.G.6
  • 4
    • 0033527663 scopus 로고    scopus 로고
    • Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
    • Oakley R.H., Laporte S.A., Holt J.A., Barak L.S., and Caron M.G. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J. Biol. Chem. 274 (1999) 32248-32257
    • (1999) J. Biol. Chem. , vol.274 , pp. 32248-32257
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 5
    • 0029897495 scopus 로고    scopus 로고
    • Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation
    • Scheer A., Fanelli F., Costa T., De Benedetti P.G., and Cotecchia S. Constitutively active mutants of the alpha 1B-adrenergic receptor: role of highly conserved polar amino acids in receptor activation. Embo. J. 15 (1996) 3566-3578
    • (1996) Embo. J. , vol.15 , pp. 3566-3578
    • Scheer, A.1    Fanelli, F.2    Costa, T.3    De Benedetti, P.G.4    Cotecchia, S.5
  • 6
    • 0033974265 scopus 로고    scopus 로고
    • Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation
    • Scheer A., Costa T., Fanelli F., De Benedetti P.G., Mhaouty-Kodja S., Abuin L., Nenniger-Tosato M., and Cotecchia S. Mutational analysis of the highly conserved arginine within the Glu/Asp-Arg-Tyr motif of the alpha(1b)-adrenergic receptor: effects on receptor isomerization and activation. Mol. Pharmacol. 57 (2000) 219-231
    • (2000) Mol. Pharmacol. , vol.57 , pp. 219-231
    • Scheer, A.1    Costa, T.2    Fanelli, F.3    De Benedetti, P.G.4    Mhaouty-Kodja, S.5    Abuin, L.6    Nenniger-Tosato, M.7    Cotecchia, S.8
  • 7
    • 0034112037 scopus 로고    scopus 로고
    • The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor
    • Alewijnse A.E., Timmerman H., Jacobs E.H., Smit M.J., Roovers E., Cotecchia S., and Leurs R. The effect of mutations in the DRY motif on the constitutive activity and structural instability of the histamine H(2) receptor. Mol. Pharmacol. 57 (2000) 890-898
    • (2000) Mol. Pharmacol. , vol.57 , pp. 890-898
    • Alewijnse, A.E.1    Timmerman, H.2    Jacobs, E.H.3    Smit, M.J.4    Roovers, E.5    Cotecchia, S.6    Leurs, R.7
  • 8
    • 22344436511 scopus 로고    scopus 로고
    • A GPCR that is not "DRY"
    • Flanagan C.A. A GPCR that is not "DRY". Mol. Pharmacol. 68 (2005) 1-3
    • (2005) Mol. Pharmacol. , vol.68 , pp. 1-3
    • Flanagan, C.A.1
  • 9
    • 0025605252 scopus 로고
    • Gene cloning of human dopaminergic D3 receptor and identification of its chromosome
    • Giros B., Martres M.P., Sokoloff P., and Schwartz J.C. Gene cloning of human dopaminergic D3 receptor and identification of its chromosome. C R Acad. Sci. III 311 (1990) 501-508
    • (1990) C R Acad. Sci. III , vol.311 , pp. 501-508
    • Giros, B.1    Martres, M.P.2    Sokoloff, P.3    Schwartz, J.C.4
  • 10
    • 0035813153 scopus 로고    scopus 로고
    • Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins
    • Kim K.M., Valenzano K.J., Robinson S.R., Yao W.D., Barak L.S., and Caron M.G. Differential regulation of the dopamine D2 and D3 receptors by G protein-coupled receptor kinases and beta-arrestins. J. Biol. Chem. 276 (2001) 37409-37414
    • (2001) J. Biol. Chem. , vol.276 , pp. 37409-37414
    • Kim, K.M.1    Valenzano, K.J.2    Robinson, S.R.3    Yao, W.D.4    Barak, L.S.5    Caron, M.G.6
  • 12
    • 3142652042 scopus 로고    scopus 로고
    • Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase
    • Beom S., Cheong D., Torres G., Caron M.G., and Kim K.M. Comparative studies of molecular mechanisms of dopamine D2 and D3 receptors for the activation of extracellular signal-regulated kinase. J. Biol. Chem. 279 (2004) 28304-28314
    • (2004) J. Biol. Chem. , vol.279 , pp. 28304-28314
    • Beom, S.1    Cheong, D.2    Torres, G.3    Caron, M.G.4    Kim, K.M.5
  • 13
    • 16844377622 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation
    • Kim K.M., Gainetdinov R.R., Laporte S.A., Caron M.G., and Barak L.S. G protein-coupled receptor kinase regulates dopamine D3 receptor signaling by modulating the stability of a receptor-filamin-beta-arrestin complex. A case of autoreceptor regulation. J. Biol. Chem. 280 (2005) 12774-12780
    • (2005) J. Biol. Chem. , vol.280 , pp. 12774-12780
    • Kim, K.M.1    Gainetdinov, R.R.2    Laporte, S.A.3    Caron, M.G.4    Barak, L.S.5
  • 14
    • 0029666441 scopus 로고    scopus 로고
    • Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells
    • Robinson S.W., and Caron M.G. Chimeric D2/D3 dopamine receptors efficiently inhibit adenylyl cyclase in HEK 293 cells. J. Neurochem. 67 (1996) 212-219
    • (1996) J. Neurochem. , vol.67 , pp. 212-219
    • Robinson, S.W.1    Caron, M.G.2
  • 16
    • 0037458614 scopus 로고    scopus 로고
    • The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
    • Tohgo A., Choy E.W., Gesty-Palmer D., Pierce K.L., Laporte S., Oakley R.H., Caron M.G., Lefkowitz R.J., and Luttrell L.M. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J. Biol. Chem. 278 (2003) 6258-6567
    • (2003) J. Biol. Chem. , vol.278 , pp. 6258-6567
    • Tohgo, A.1    Choy, E.W.2    Gesty-Palmer, D.3    Pierce, K.L.4    Laporte, S.5    Oakley, R.H.6    Caron, M.G.7    Lefkowitz, R.J.8    Luttrell, L.M.9
  • 17
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by beta-arrestins
    • Lefkowitz R.J., and Shenoy S.K. Transduction of receptor signals by beta-arrestins. Science 308 (2005) 512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 18
    • 0030736417 scopus 로고    scopus 로고
    • A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
    • Barak L.S., Ferguson S.S., Zhang J., and Caron M.G. A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. J. Biol. Chem. 272 (1997) 27497-27500
    • (1997) J. Biol. Chem. , vol.272 , pp. 27497-27500
    • Barak, L.S.1    Ferguson, S.S.2    Zhang, J.3    Caron, M.G.4
  • 19
    • 0030775397 scopus 로고    scopus 로고
    • Selective inhibition of adenylyl cyclase type V by the dopamine D3 receptor
    • Robinson S.W., and Caron M.G. Selective inhibition of adenylyl cyclase type V by the dopamine D3 receptor. Mol. Pharmacol. 52 (1997) 508-514
    • (1997) Mol. Pharmacol. , vol.52 , pp. 508-514
    • Robinson, S.W.1    Caron, M.G.2
  • 20
    • 33947381686 scopus 로고    scopus 로고
    • The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state
    • Rovati G.E., Capra V., and Neubig R.R. The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state. Mol. Pharmacol. 71 (2007) 959-964
    • (2007) Mol. Pharmacol. , vol.71 , pp. 959-964
    • Rovati, G.E.1    Capra, V.2    Neubig, R.R.3
  • 21
    • 4344646417 scopus 로고    scopus 로고
    • Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation
    • Barak L.S., Wilbanks A.M., and Caron M.G. Constitutive desensitization: a new paradigm for g protein-coupled receptor regulation. Assay Drug Dev. Technol. 1 (2003) 339-346
    • (2003) Assay Drug Dev. Technol. , vol.1 , pp. 339-346
    • Barak, L.S.1    Wilbanks, A.M.2    Caron, M.G.3
  • 22
    • 0037088585 scopus 로고    scopus 로고
    • Beta-arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation
    • Tohgo A., Pierce K.L., Choy E.W., Lefkowitz R.J., and Luttrell L.M. Beta-arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation. J. Biol. Chem. 277 (2002) 9429-9436
    • (2002) J. Biol. Chem. , vol.277 , pp. 9429-9436
    • Tohgo, A.1    Pierce, K.L.2    Choy, E.W.3    Lefkowitz, R.J.4    Luttrell, L.M.5
  • 23
    • 1542350042 scopus 로고    scopus 로고
    • Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2
    • Ahn S., Wei H., Garrison T.R., and Lefkowitz R.J. Reciprocal regulation of angiotensin receptor-activated extracellular signal-regulated kinases by beta-arrestins 1 and 2. J. Biol. Chem. 279 (2004) 7807-7811
    • (2004) J. Biol. Chem. , vol.279 , pp. 7807-7811
    • Ahn, S.1    Wei, H.2    Garrison, T.R.3    Lefkowitz, R.J.4
  • 24
    • 4143070533 scopus 로고    scopus 로고
    • Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor
    • Ahn S., Shenoy S.K., Wei H., and Lefkowitz R.J. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. J. Biol. Chem. 279 (2004) 35518-35525
    • (2004) J. Biol. Chem. , vol.279 , pp. 35518-35525
    • Ahn, S.1    Shenoy, S.K.2    Wei, H.3    Lefkowitz, R.J.4
  • 26
    • 0034595860 scopus 로고    scopus 로고
    • Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
    • Oakley R.H., Laporte S.A., Holt J.A., Caron M.G., and Barak L.S. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J. Biol. Chem. 275 (2000) 17201-17210
    • (2000) J. Biol. Chem. , vol.275 , pp. 17201-17210
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Caron, M.G.4    Barak, L.S.5
  • 27
    • 0037044297 scopus 로고    scopus 로고
    • Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors
    • Wilbanks A.M., Laporte S.A., Bohn L.M., Barak L.S., and Caron M.G. Apparent loss-of-function mutant GPCRs revealed as constitutively desensitized receptors. Biochemistry 41 (2002) 11981-11989
    • (2002) Biochemistry , vol.41 , pp. 11981-11989
    • Wilbanks, A.M.1    Laporte, S.A.2    Bohn, L.M.3    Barak, L.S.4    Caron, M.G.5
  • 28
    • 22344450701 scopus 로고    scopus 로고
    • High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3
    • Rosenkilde M.M., Kledal T.N., and Schwartz T.W. High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3. Mol. Pharmacol. 68 (2005) 11-19
    • (2005) Mol. Pharmacol. , vol.68 , pp. 11-19
    • Rosenkilde, M.M.1    Kledal, T.N.2    Schwartz, T.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.