Constitutively active mutants of the α(1B)-adrenergic receptor: Role of highly conserved polar amino acids in receptor activation

EMBO Journal

Volumn 15, Issue 14, 1996, Pages 3566-3578

  Scheer, Alexander ^a   Fanelli, Francesca ^b   Costa, Tommaso ^c   De Benedetti, Pier G ^b   Cotecchia, Susanna ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Computational simulations; Constitutively active receptors; G protein coupled receptors; Molecular dynamics

Indexed keywords

ALPHA 1B ADRENERGIC RECEPTOR; MUTANT PROTEIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; MODEL; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTON TRANSPORT; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0029897495     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00726.x     Document Type: Article

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