-
1
-
-
33750461663
-
P27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: A proof-of-concept study
-
DOI 10.1007/s00018-006-6194-4
-
H Akashiba N Matsuki N Nishiyama 2006 p27 small interfering RNA induces cell death through elevating cell cycle activity in cultured cortical neurons: a proof-of-concept study Cell Mol Life Sci 63 2397 2404 17006629 1:CAS:528:DC%2BD28XhtFyrtrvL (Pubitemid 44653049)
-
(2006)
Cellular and Molecular Life Sciences
, vol.63
, Issue.19-20
, pp. 2397-2404
-
-
Akashiba, H.1
Matsuki, N.2
Nishiyama, N.3
-
2
-
-
44449105174
-
Differential involvement of cell cycle reactivation between striatal and cortical neurons in cell death induced by 3-nitropropionic acid
-
18182390 1:CAS:528:DC%2BD1cXisFOkt7k%3D
-
H Akashiba Y Ikegaya N Nishiyama N Matsuki 2008 Differential involvement of cell cycle reactivation between striatal and cortical neurons in cell death induced by 3-nitropropionic acid J Biol Chem 283 6594 6606 18182390 1:CAS:528:DC%2BD1cXisFOkt7k%3D
-
(2008)
J Biol Chem
, vol.283
, pp. 6594-6606
-
-
Akashiba, H.1
Ikegaya, Y.2
Nishiyama, N.3
Matsuki, N.4
-
3
-
-
34247490197
-
Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
-
DOI 10.1016/j.neuroscience.2007.01.042, PII S0306452207000802
-
D Alvira M Tajes E Verdaguer SG de Arriba C Allgaier C Matute R Trullas A Jiménez M Pallàs A Camins 2007 Inhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons Neuroscience 146 350 365 17343987 1:CAS:528:DC%2BD2sXkslais7g%3D (Pubitemid 46654625)
-
(2007)
Neuroscience
, vol.146
, Issue.1
, pp. 350-365
-
-
Alvira, D.1
Tajes, M.2
Verdaguer, E.3
De Arriba, S.G.4
Allgaier, C.5
Matute, C.6
Trullas, R.7
Jimenez, A.8
Pallas, M.9
Camins, A.10
-
4
-
-
44249113558
-
Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease
-
DOI 10.1016/j.parkreldis.2007.09.005, PII S1353802007002052
-
D Alvira I Ferrer J Gutierrez-Cuesta B Garcia-Castro M Pallàs A Camins 2008 Activation of the calpain/cdk5/p25 pathway in the girus cinguli in Parkinson's disease Parkinsonism Relat Disord 14 309 313 17977053 (Pubitemid 351726515)
-
(2008)
Parkinsonism and Related Disorders
, vol.14
, Issue.4
, pp. 309-313
-
-
Alvira, D.1
Ferrer, I.2
Gutierrez-Cuesta, J.3
Garcia-Castro, B.4
Pallas, M.5
Camins, A.6
-
5
-
-
33744982418
-
Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons
-
DOI 10.1016/j.lfs.2006.01.032, PII S0024320506000798
-
A Appert-Collin B Hugel R Levy N Niederhoffer G Coupin Y Lombard P André P Poindron JP Gies 2006 Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons Life Sci 79 484 490 16530228 1:CAS:528:DC%2BD28XlsFGktr4%3D (Pubitemid 43866127)
-
(2006)
Life Sciences
, vol.79
, Issue.5
, pp. 484-490
-
-
Appert-Collin, A.1
Hugel, B.2
Levy, R.3
Niederhoffer, N.4
Coupin, G.5
Lombard, Y.6
Andre, P.7
Poindron, P.8
Gies, J.P.9
-
6
-
-
67349213205
-
Synaptic degeneration in Alzheimer's disease
-
19390859
-
T Arendt 2009 Synaptic degeneration in Alzheimer's disease Acta Neuropathol 118 167 179 19390859
-
(2009)
Acta Neuropathol
, vol.118
, pp. 167-179
-
-
Arendt, T.1
-
7
-
-
0030454478
-
Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease
-
T Arendt L Rödel U Gärtner M Holzer 1996 Expression of the cyclin-dependent kinase inhibitor p16 in Alzheimer's disease Neuroreport 7 3047 3049 9116237 1:STN:280:DyaK2s7ms1ertA%3D%3D (Pubitemid 26426387)
-
(1996)
NeuroReport
, vol.7
, Issue.18
, pp. 3047-3049
-
-
Arendt, T.1
Rodel, L.2
Gartner, U.3
Holzer, M.4
-
8
-
-
0031737550
-
Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease
-
DOI 10.1007/s007020050104
-
T Arendt M Holzer U Gärtner 1998 Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease J Neural Transm 105 949 960 9869328 1:CAS:528:DyaK1MXhsVOluw%3D%3D (Pubitemid 28539839)
-
(1998)
Journal of Neural Transmission
, vol.105
, Issue.8-9
, pp. 949-960
-
-
Arendt, T.1
Holzer, M.2
Gartner, U.3
-
9
-
-
84855712104
-
Pin1 inhibition activates cyclin D and produces neurodegenerative pathology
-
Mar 28. doi: 10.1111/j.1471-4159.2011.07259.x.[Epubaheadofprint]
-
Atabay KD, Karabay A. Pin1 inhibition activates cyclin D and produces neurodegenerative pathology. J Neurochem. 2011 Mar 28. doi: 10.1111/j.1471-4159. 2011.07259.x. [Epub ahead of print]
-
(2011)
J Neurochem.
-
-
Atabay, K.D.1
Karabay, A.2
-
10
-
-
9144269626
-
Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons: Modulation during neuronal apoptosis
-
DOI 10.1016/j.mcn.2003.08.002
-
C Barbato N Corbi N Canu M Fanciulli A Serafino M Ciotti V Libri T Bruno G Amadoro R De Angelis P Calissano C Passananti 2003 Rb binding protein Che-1 interacts with Tau in cerebellar granule neurons. Modulation during neuronal apoptosis Mol Cell Neurosci 24 1038 1050 14697667 1:CAS:528:DC%2BD3sXpvFymtrc%3D (Pubitemid 38091515)
-
(2003)
Molecular and Cellular Neuroscience
, vol.24
, Issue.4
, pp. 1038-1050
-
-
Barbato, C.1
Corbi, N.2
Canu, N.3
Fanciulli, M.4
Serafino, A.5
Ciotti, M.6
Libri, V.7
Bruno, T.8
Amadoro, G.9
De Angelis, R.10
Calissano, P.11
Passananti, C.12
-
11
-
-
77957767952
-
JNK activation is regulated by E2F and promotes E2F1-induced apoptosis
-
20800677 1:CAS:528:DC%2BC3cXht12lu7zF
-
D Bashari D Hacohen D Ginsberg 2011 JNK activation is regulated by E2F and promotes E2F1-induced apoptosis Cell Signal 23 65 70 20800677 1:CAS:528:DC%2BC3cXht12lu7zF
-
(2011)
Cell Signal
, vol.23
, pp. 65-70
-
-
Bashari, D.1
Hacohen, D.2
Ginsberg, D.3
-
12
-
-
0027757042
-
Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5
-
DOI 10.1016/0014-5793(93)80849-P
-
K Baumann EM Mandelkow J Biernat H Piwnica-Worms E Mandelkow 1993 Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5 FEBS Lett 336 417 424 8282104 1:CAS:528:DyaK2cXhtlWgsb8%3D (Pubitemid 24036992)
-
(1993)
FEBS Letters
, vol.336
, Issue.3
, pp. 417-424
-
-
Baumann, K.1
-
13
-
-
1542381057
-
Cell cycle regulation of neuronal apoptosis in development and disease
-
DOI 10.1016/j.pneurobio.2003.12.005, PII S0301008203002053
-
Becker EB, Bonni A (2004) Cell cycle regulation of neuronal apoptosis in development and disease. Prog Neurobiol 72:1-25 (Pubitemid 38294359)
-
(2004)
Progress in Neurobiology
, vol.72
, Issue.1
, pp. 1-25
-
-
Becker, E.B.E.1
Bonni, A.2
-
14
-
-
24944474714
-
Bim is a direct target of a neuronal E2F-dependent apoptotic pathway
-
DOI 10.1523/JNEUROSCI.1570-05.2005
-
SC Biswas DX Liu LA Greene 2005 Bim is a direct target of a neuronal E2F-dependent apoptotic pathway J Neurosci 25 8349 8358 16162916 1:CAS:528:DC%2BD2MXhtVert7nN (Pubitemid 41324721)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.37
, pp. 8349-8358
-
-
Biswas, S.C.1
Liu, D.X.2
Greene, L.A.3
-
15
-
-
44949238447
-
The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
-
18456574 1:CAS:528:DC%2BD1cXnt1aksbk%3D
-
S Biton A Barzilai Y Shiloh 2008 The neurological phenotype of ataxia-telangiectasia: solving a persistent puzzle DNA Repair 7 1028 1038 18456574 1:CAS:528:DC%2BD1cXnt1aksbk%3D
-
(2008)
DNA Repair
, vol.7
, pp. 1028-1038
-
-
Biton, S.1
Barzilai, A.2
Shiloh, Y.3
-
16
-
-
77949884756
-
Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease
-
1:CAS:528:DC%2BD1MXht1GkurnK
-
DJ Bonda TA Evans C Santocanale JC Llosá J Viña VP Bajic RJ Castellani SL Siedlak G Perry MA Smith HG Lee 2009 Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease Aging (Albany NY) 1 382 388 1:CAS:528:DC%2BD1MXht1GkurnK
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 382-388
-
-
Bonda, D.J.1
Evans, T.A.2
Santocanale, C.3
Llosá, J.C.4
Viña, J.5
Bajic, V.P.6
Castellani, R.J.7
Siedlak, S.L.8
Perry, G.9
Smith, M.A.10
Lee, H.G.11
-
18
-
-
0032815680
-
Replicating Huntington's disease phenotype in experimental animals
-
DOI 10.1016/S0301-0082(99)00005-2, PII S0301008299000052
-
E Brouillet F Condé MF Beal P Hantraye 1999 Replicating Huntington's disease phenotype in experimental animals Prog Neurobiol 59 427 468 10515664 1:CAS:528:DyaK1MXmsFOhs7c%3D (Pubitemid 29392967)
-
(1999)
Progress in Neurobiology
, vol.59
, Issue.5
, pp. 427-468
-
-
Brouillet, E.1
Conde, F.2
Beal, M.F.3
Hantraye, P.4
-
19
-
-
29144468251
-
3-Nitropropionic acid: A mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease
-
DOI 10.1111/j.1471-4159.2005.03515.x
-
E Brouillet C Jacquard N Bizat D Blum 2005 3-Nitropropionic acid: a mitochondrial toxin to uncover physiopathological mechanisms underlying striatal degeneration in Huntington's disease J Neurochem 95 1521 1540 16300642 1:CAS:528:DC%2BD28XhsVKjtQ%3D%3D (Pubitemid 41804051)
-
(2005)
Journal of Neurochemistry
, vol.95
, Issue.6
, pp. 1521-1540
-
-
Brouillet, E.1
Jacquard, C.2
Bizat, N.3
Blum, D.4
-
20
-
-
35348889576
-
Inhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis
-
DOI 10.2174/138920007782109814
-
A Camins E Verdaguer J Folch C Beas-Zarate AM Canudas M Pallàs 2007 Inhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis Curr Drug Metab 8 709 715 17979659 1:CAS:528:DC%2BD2sXhtFKjsbbN (Pubitemid 47578119)
-
(2007)
Current Drug Metabolism
, vol.8
, Issue.7
, pp. 709-715
-
-
Camins, A.1
Verdaguer, E.2
Folch, J.3
Beas-Zarate, C.4
Canudas, A.M.5
Pallas, M.6
-
21
-
-
78149467894
-
Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease
-
20502937 1:CAS:528:DC%2BC3cXht12qurrK
-
A Camins JG Pizarro D Alvira J Gutierrez-Cuesta AV de la Torre J Folch FX Sureda E Verdaguer F Junyent J Jordán I Ferrer M Pallàs 2010 Activation of ataxia telangiectasia muted under experimental models and human Parkinson's disease Cell Mol Life Sci 67 3865 3882 20502937 1:CAS:528: DC%2BC3cXht12qurrK
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3865-3882
-
-
Camins, A.1
Pizarro, J.G.2
Alvira, D.3
Gutierrez-Cuesta, J.4
De La Torre, A.V.5
Folch, J.6
Sureda, F.X.7
Verdaguer, E.8
Junyent, F.9
Jordán, J.10
Ferrer, I.11
Pallàs, M.12
-
22
-
-
25444457320
-
Role of the cell cycle in the pathobiology of central nervous system trauma
-
I Cernak B Stoica KR Byrnes S Di Giovanni AI Faden 2005 Role of the cell cycle in the pathobiology of central nervous system trauma Cell Cycle 4 1286 1293 16082214 1:CAS:528:DC%2BD28XktVCgtbY%3D (Pubitemid 41365402)
-
(2005)
Cell Cycle
, vol.4
, Issue.9
, pp. 1286-1293
-
-
Cernak, I.1
Stoica, B.2
Byrnes, K.R.3
Di Giovanni, S.4
Faden, A.I.5
-
23
-
-
77951932919
-
Cdk5 is a major regulator of p38 cascade: Relevance to neurotoxicity in Alzheimer's disease
-
20345761 1:CAS:528:DC%2BC3cXnt1Gnsb4%3D
-
KH Chang Y de Pablo HP Lee HG Lee MA Smith K Shah 2010 Cdk5 is a major regulator of p38 cascade: relevance to neurotoxicity in Alzheimer's disease J Neurochem 113 1221 1229 20345761 1:CAS:528:DC%2BC3cXnt1Gnsb4%3D
-
(2010)
J Neurochem
, vol.113
, pp. 1221-1229
-
-
Chang, K.H.1
De Pablo, Y.2
Lee, H.P.3
Lee, H.G.4
Smith, M.A.5
Shah, K.6
-
24
-
-
18844440792
-
Employing new cellular therapeutic targets for Alzheimer's disease: A change for the better?
-
DOI 10.2174/1567202052773508
-
ZZ Chong F Li K Maiese 2005 Employing new cellular therapeutic targets for Alzheimer's disease: a change for the better? Curr Neurovasc Res 2 55 72 16181100 1:CAS:528:DC%2BD2MXitFyktrk%3D (Pubitemid 41419946)
-
(2005)
Current Neurovascular Research
, vol.2
, Issue.1
, pp. 55-72
-
-
Chong, Z.Z.1
Li, F.2
Maiese, K.3
-
25
-
-
0032787503
-
Mitotic signaling by beta-amyloid causes neuronal death
-
10593870 1:CAS:528:DyaK1MXotVKitb4%3D
-
A Copani F Condorelli A Caruso C Vancheri A Sala AM Giuffrida Stella PL Canonico F Nicoletti MA Sortino 1999 Mitotic signaling by beta-amyloid causes neuronal death FASEB J 13 2225 2234 10593870 1:CAS:528:DyaK1MXotVKitb4%3D
-
(1999)
FASEB J
, vol.13
, pp. 2225-2234
-
-
Copani, A.1
Condorelli, F.2
Caruso, A.3
Vancheri, C.4
Sala, A.5
Giuffrida Stella, A.M.6
Canonico, P.L.7
Nicoletti, F.8
Sortino, M.A.9
-
26
-
-
0035058466
-
Activation of cell-cycle-associated proteins in neuronal death: A mandatory or dispensable path?
-
DOI 10.1016/S0166-2236(00)01663-5, PII S0166223600016635
-
A Copani D Uberti MA Sortino V Bruno F Nicoletti M Memo 2001 Activation of cell-cycle-associated proteins in neuronal death: a mandatory or dispensable path? Trends Neurosci 24 25 31 11163884 1:CAS:528:DC%2BD3MXktl2rtQ%3D%3D (Pubitemid 32332893)
-
(2001)
Trends in Neurosciences
, vol.24
, Issue.1
, pp. 25-31
-
-
Copani, A.1
Ubertia, D.2
Sortino, M.A.3
Bruno, V.4
Nicoletti, F.5
Memo, M.6
-
27
-
-
0036884184
-
Erratic expression of DNA polymerases by beta-amyloid causes neuronal death
-
12397084 1:CAS:528:DC%2BD38Xps1OjsbY%3D
-
A Copani MA Sortino A Caricasole S Chiechio M Chisari G Battaglia AM Giuffrida-Stella C Vancheri F Nicoletti 2002 Erratic expression of DNA polymerases by beta-amyloid causes neuronal death FASEB J 16 2006 2008 12397084 1:CAS:528:DC%2BD38Xps1OjsbY%3D
-
(2002)
FASEB J
, vol.16
, pp. 2006-2008
-
-
Copani, A.1
Sortino, M.A.2
Caricasole, A.3
Chiechio, S.4
Chisari, M.5
Battaglia, G.6
Giuffrida-Stella, A.M.7
Vancheri, C.8
Nicoletti, F.9
-
28
-
-
33947185406
-
The nature of the cell cycle in neurons: Focus on a "non- canonical" pathway of DNA replication causally related to death
-
DOI 10.1016/j.bbadis.2006.10.016, PII S0925443906002328
-
A Copani F Caraci JJ Hoozemans M Calafiore MA Sortino F Nicoletti 2007 The nature of the cell cycle in neurons: focus on a "non-canonical" pathway of DNA replication causally related to death Biochim Biophys Acta 1772 409 412 17196375 1:CAS:528:DC%2BD2sXjtVahur0%3D (Pubitemid 46400384)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.4
, pp. 409-412
-
-
Copani, A.1
Caraci, F.2
Hoozemans, J.J.M.3
Calafiore, M.4
Angela Sortino, M.5
Nicoletti, F.6
-
29
-
-
55249091338
-
The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development
-
18855671 1:CAS:528:DC%2BD1cXhtFCqsLbP
-
A Copani S Guccione L Giurato F Caraci M Calafiore MA Sortino F Nicoletti 2008 The cell cycle molecules behind neurodegeneration in Alzheimer's disease: perspectives for drug development Curr Med Chem 15 2420 2432 18855671 1:CAS:528:DC%2BD1cXhtFCqsLbP
-
(2008)
Curr Med Chem
, vol.15
, pp. 2420-2432
-
-
Copani, A.1
Guccione, S.2
Giurato, L.3
Caraci, F.4
Calafiore, M.5
Sortino, M.A.6
Nicoletti, F.7
-
30
-
-
7744244181
-
P53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death
-
DOI 10.1523/JNEUROSCI.2114-04.2004
-
SP Cregan NA Arbour JG Maclaurin SM Callaghan A Fortin EC Cheung DS Guberman DS Park RS Slack 2004 p53 activation domain 1 is essential for PUMA upregulation and p53-mediated neuronal cell death J Neurosci 24 10003 10012 15525786 1:CAS:528:DC%2BD2cXhtVWht7%2FL (Pubitemid 39463582)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.44
, pp. 10003-10012
-
-
Cregan, S.P.1
Arbour, N.A.2
MacLaurin, J.G.3
Callaghan, S.M.4
Fortin, A.5
Cheung, E.C.C.6
Guberman, D.S.7
Park, D.S.8
Slack, R.S.9
-
31
-
-
85047698254
-
Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter
-
DOI 10.1038/sj/onc/1205232
-
Croxton R, Ma Y, Cress WD (2002) Differences in DNA binding properties between E2F1 and E2F4 specify repression of the Mcl-1 promoter. Oncogene 21:1563-1570 (Pubitemid 34226144)
-
(2002)
Oncogene
, vol.21
, Issue.10
, pp. 1563-1570
-
-
Croxton, R.1
Ma, Y.2
Cress, W.D.3
-
32
-
-
4444262625
-
Cdk5 deregulation in the pathogenesis of Alzheimer's disease
-
DOI 10.1016/j.molmed.2004.07.001, PII S1471491404001807
-
JC Cruz LH Tsai 2004 Cdk5 deregulation in the pathogenesis of Alzheimer's disease Trends Mol Med 10 452 458 15350898 1:CAS:528:DC%2BD2cXntlGhur0%3D (Pubitemid 39209212)
-
(2004)
Trends in Molecular Medicine
, vol.10
, Issue.9
, pp. 452-458
-
-
Cruz, J.C.1
Tsai, L.-H.2
-
33
-
-
0345405447
-
Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles
-
DOI 10.1016/S0896-6273(03)00627-5
-
Cruz JC, Tseng HC, Goldman JA, Shih H, Tsai LH (2003) Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron 40:471-483 (Pubitemid 37494698)
-
(2003)
Neuron
, vol.40
, Issue.3
, pp. 471-483
-
-
Cruz, J.C.1
Tseng, H.-C.2
Goldman, J.A.3
Shih, H.4
Tsai, L.-H.5
-
34
-
-
71949108518
-
Mitochondria in Huntington's disease
-
19682570 1:CAS:528:DC%2BD1MXhsFanurbM
-
M Damiano L Galvan N Déglon E Brouillet 2010 Mitochondria in Huntington's disease Biochim Biophys Acta 1802 52 61 19682570 1:CAS:528:DC%2BD1MXhsFanurbM
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 52-61
-
-
Damiano, M.1
Galvan, L.2
Déglon, N.3
Brouillet, E.4
-
35
-
-
20444427615
-
Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury
-
DOI 10.1073/pnas.0500989102
-
S Di Giovanni V Movsesyan F Ahmed I Cernak S Schinelli B Stoica AI Faden 2005 Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury Proc Natl Acad Sci USA 102 8333 8338 15923260 1:CAS:528:DC%2BD2MXlsV2mtbw%3D (Pubitemid 40800089)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.23
, pp. 8333-8338
-
-
Di Giovanni, S.1
Movsesyan, V.2
Ahmed, F.3
Cernak, I.4
Schinelli, S.5
Stoica, B.6
Faden, A.I.7
-
36
-
-
18344393150
-
The E2F transcriptional network: Old acquaintances with new faces
-
DOI 10.1038/sj.onc.1208612
-
DK Dimova NJ Dyson 2005 The E2F transcriptional network: old acquaintances with new faces Oncogene 24 2810 2826 15838517 1:CAS:528: DC%2BD2MXjtlehs7g%3D (Pubitemid 40638092)
-
(2005)
Oncogene
, vol.24
, Issue.17
, pp. 2810-2826
-
-
Dimova, D.K.1
Dyson, N.J.2
-
37
-
-
0035950521
-
Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1
-
DOI 10.1038/sj.onc.1204892
-
CM Eischen G Packham J Nip BE Fee SW Hiebert GP Zambetti JL Cleveland 2001 Bcl-2 is an apoptotic target suppressed by both c-Myc and E2F-1 Oncogene 20 6983 6993 11704823 1:CAS:528:DC%2BD3MXotlCgtbc%3D (Pubitemid 33052191)
-
(2001)
Oncogene
, vol.20
, Issue.48
, pp. 6983-6993
-
-
Eischen, C.M.1
Packham, G.2
Nip, J.3
Fee, B.E.4
Hiebert, S.W.5
Zambetti, G.P.6
Cleveland, J.L.7
-
38
-
-
78349312360
-
Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease
-
20732420
-
MR Fernandez-Fernandez I Ferrer JJ Lucas 2011 Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease Neurobiol Dis 41 23 32 20732420
-
(2011)
Neurobiol Dis
, vol.41
, pp. 23-32
-
-
Fernandez-Fernandez, M.R.1
Ferrer, I.2
Lucas, J.J.3
-
39
-
-
18644381327
-
Apaf-1 is a mediator of E2F-1-induced apoptosis
-
DOI 10.1074/jbc.M200805200
-
Y Furukawa N Nishimura Y Furukawa M Satoh H Endo S Iwase H Yamada M Matsuda Y Kano M Nakamura 2002 Apaf-1 is a mediator of E2F-1-induced apoptosis J Biol Chem 277 39760 39768 12149244 1:CAS:528:DC%2BD38XnvVeiu7Y%3D (Pubitemid 35190959)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39760-39768
-
-
Furukawa, Y.1
Nishimura, N.2
Furukawa, Y.3
Satoh, M.4
Endo, H.5
Iwase, S.6
Yamada, H.7
Matsuda, M.8
Kano, Y.9
Nakamura, M.10
-
40
-
-
0034697299
-
E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3
-
DOI 10.1074/jbc.275.16.11553
-
A Giovanni E Keramaris EJ Morris ST Hou M O'Hare N Dyson GS Robertson RS Slack DS Park 2000 E2F1 mediates death of B-amyloid-treated cortical neurons in a manner independent of p53 and dependent on Bax and caspase 3 J Biol Chem 275 11553 11560 10766769 1:CAS:528:DC%2BD3cXislyqur0%3D (Pubitemid 30237711)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.16
, pp. 11553-11560
-
-
Giovanni, A.1
Keramaris, E.2
Morris, E.J.3
Hou, S.T.4
O'Hare, M.5
Dyson, N.6
Robertson, G.S.7
Slack, R.S.8
Park, D.S.9
-
41
-
-
7044237034
-
Divide and die: Cell cycle events as triggers of nerve cell death
-
DOI 10.1523/JNEUROSCI.3347-04.2004
-
K Herrup R Neve SL Ackerman A Copani 2004 Divide and die: cell cycle events as triggers of nerve cell death J Neurosci 24 9232 9239 15496657 1:CAS:528:DC%2BD2cXpsVWgsrs%3D (Pubitemid 39426158)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.42
, pp. 9232-9239
-
-
Herrup, K.1
Neve, R.2
Ackerman, S.L.3
Copani, A.4
-
42
-
-
1542305653
-
Up-regulation of Bcl-2 Homology 3 (BH3)-only Proteins by E2F1 Mediates Apoptosis
-
DOI 10.1074/jbc.M312866200
-
Hershko T, Ginsberg D (2004) Up-regulation of Bcl-2 homology 3 (BH3)-only proteins by E2F1 mediates apoptosis. J Biol Chem 279:8627-8634 (Pubitemid 38295917)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.10
, pp. 8627-8634
-
-
Hershko, T.1
Ginsberg, D.2
-
43
-
-
33847610595
-
The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease
-
DOI 10.1073/pnas.0611671104
-
GU Höglinger JJ Breunig C Depboylu C Rouaux PP Michel D Alvarez-Fischer AL Boutillier J Degregori WH Oertel P Rakic EC Hirsch S Hunot 2007 The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease Proc Natl Acad Sci USA 104 3585 3590 17360686 (Pubitemid 46364202)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.9
, pp. 3585-3590
-
-
Hoglinger, G.U.1
Breunig, J.J.2
Depboylu, C.3
Rouaux, C.4
Michel, P.P.5
Alvarez-Fischer, D.6
Boutillier, A.-L.7
DeGregori, J.8
Oertel, W.H.9
Rakic, P.10
Hirsch, E.C.11
Hunot, S.12
-
44
-
-
0034086552
-
The transcription factor E2f1 modulates apoptosis of neurons
-
DOI 10.1046/j.1471-4159.2000.0750091.x
-
ST Hou D Callaghan MC Fournier I Hill L Kang B Massie P Morley C Murray I Rasquinha R Slack JP MacManus 2000 The transcription factor E2F1 modulates apoptosis of neurons J Neurochem 75 91 100 10854251 1:CAS:528: DC%2BD3cXkt12qtr0%3D (Pubitemid 30418173)
-
(2000)
Journal of Neurochemistry
, vol.75
, Issue.1
, pp. 91-100
-
-
Hou, S.T.1
Callaghan, D.2
Fournier, M.-C.3
Hill, I.4
Kang, L.5
Massie, B.6
Morley, P.7
Murray, C.8
Rasquinha, I.9
Slack, R.10
MacManus, J.P.11
-
45
-
-
0034913318
-
The transcription factor E2F1 promotes dopamine-evoked neuronal apoptosis by a mechanism independent of transcriptional activation
-
DOI 10.1046/j.1471-4159.2001.00402.x
-
ST Hou E Cowan T Walker N Ohan M Dove I Rasqinha JP MacManus 2001 The transcription factor E2F1 promotes dopamine-evoked neuronal apoptosis by a mechanism independent of transcriptional activation J Neurochem 78 287 297 11461964 1:CAS:528:DC%2BD3MXlsVeisbk%3D (Pubitemid 32664410)
-
(2001)
Journal of Neurochemistry
, vol.78
, Issue.2
, pp. 287-297
-
-
Hou, S.T.1
Cowan, E.2
Walker, T.3
Ohan, N.4
Dove, M.5
Rasqinha, I.6
MacManus, J.P.7
-
46
-
-
77955735085
-
Cdk5: Links to DNA damage
-
20724832 1:CAS:528:DC%2BC3MXhs12hug%3D%3D
-
E Huang D Qu DS Park 2010 Cdk5: links to DNA damage Cell Cycle 9 3142 3143 20724832 1:CAS:528:DC%2BC3MXhs12hug%3D%3D
-
(2010)
Cell Cycle
, vol.9
, pp. 3142-3143
-
-
Huang, E.1
Qu, D.2
Park, D.S.3
-
47
-
-
77953121792
-
The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death
-
20473298 1:CAS:528:DC%2BC3cXmslShtbk%3D
-
E Huang D Qu Y Zhang K Venderova ME Haque MW Rousseaux RS Slack JM Woulfe DS Park 2010 The role of Cdk5-mediated apurinic/apyrimidinic endonuclease 1 phosphorylation in neuronal death Nat Cell Biol 12 563 571 20473298 1:CAS:528:DC%2BC3cXmslShtbk%3D
-
(2010)
Nat Cell Biol
, vol.12
, pp. 563-571
-
-
Huang, E.1
Qu, D.2
Zhang, Y.3
Venderova, K.4
Haque, M.E.5
Rousseaux, M.W.6
Slack, R.S.7
Woulfe, J.M.8
Park, D.S.9
-
48
-
-
0034609798
-
Role for the p53 homologue p73 in E2F-1-induced apoptosis
-
Irwin M, Marin MC, Phillips AC, Seelan RS, Smith DI, Liu W, Flores ER, Tsai KY, Jacks T, Vousden KH, Kaelin WG (2000) Role for the p53 homologue p73 in E2F-1-induced apoptosis. Nature 407:645-648
-
(2000)
Nature
, vol.407
, pp. 645-648
-
-
Irwin, M.1
Marin, M.C.2
Phillips, A.C.3
Seelan, R.S.4
Smith, D.I.5
Liu, W.6
Flores, E.R.7
Tsai, K.Y.8
Jacks, T.9
Vousden, K.H.10
Kaelin, W.G.11
-
49
-
-
4344622376
-
Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains
-
DOI 10.1016/j.molbrainres.2004.05.023, PII S0169328X04002554
-
E Jacobsen T Beach Y Shen R Li Y Chang 2004 Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains Brain Res Mol Brain Res 128 1 7 15337312 1:CAS:528:DC%2BD2cXntFWrsLs%3D (Pubitemid 39158875)
-
(2004)
Molecular Brain Research
, vol.128
, Issue.1
, pp. 1-7
-
-
Jacobsen, E.1
Beach, T.2
Shen, Y.3
Li, R.4
Chang, Y.5
-
50
-
-
78049262912
-
The RB-E2F1 pathway regulates autophagy
-
20807803 1:CAS:528:DC%2BC3cXht1yqs7nM
-
H Jiang V Martin C Gomez-Manzano DG Johnson M Alonso E White J Xu TJ McDonnell N Shinojima J Fueyo 2010 The RB-E2F1 pathway regulates autophagy Cancer Res 70 7882 7893 20807803 1:CAS:528:DC%2BC3cXht1yqs7nM
-
(2010)
Cancer Res
, vol.70
, pp. 7882-7893
-
-
Jiang, H.1
Martin, V.2
Gomez-Manzano, C.3
Johnson, D.G.4
Alonso, M.5
White, E.6
Xu, J.7
McDonnell, T.J.8
Shinojima, N.9
Fueyo, J.10
-
51
-
-
0033293460
-
Increased cyclin G1 immunoreactivity during Alzheimer's disease
-
12214116 1:CAS:528:DC%2BD3cXisFSmtLg%3D
-
KL Jordan-Sciutto K Morgan R Bowser 1999 Increased cyclin G1 immunoreactivity during Alzheimer's disease J Alzheimers Dis 1 409 417 12214116 1:CAS:528:DC%2BD3cXisFSmtLg%3D
-
(1999)
J Alzheimers Dis
, vol.1
, pp. 409-417
-
-
Jordan-Sciutto, K.L.1
Morgan, K.2
Bowser, R.3
-
53
-
-
0034793625
-
Altered subcellular distribution of transcriptional regulators in response to Aβ peptide and during Alzheimer's disease
-
DOI 10.1016/S0047-6374(01)00334-7, PII S0047637401003347
-
K Jordan-Sciutto J Rhodes R Bowser 2001 Altered subcellular distribution of transcriptional regulators in response to Abeta peptide and during Alzheimer's disease Mech Ageing Dev 123 11 20 11640947 1:CAS:528: DC%2BD3MXnsF2hurs%3D (Pubitemid 32972254)
-
(2001)
Mechanisms of Ageing and Development
, vol.123
, Issue.1
, pp. 11-20
-
-
Jordan-Sciutto, K.1
Rhodes, J.2
Bowser, R.3
-
55
-
-
0037088922
-
Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis
-
KL Jordan-Sciutto G Wang M Murphey-Corb CA Wiley 2002 Cell cycle proteins exhibit altered expression patterns in lentiviral-associated encephalitis J Neurosci 22 2185 2195 11896158 1:CAS:528:DC%2BD38XisVerur0%3D (Pubitemid 35386518)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.6
, pp. 2185-2195
-
-
Jordan-Sciutto, K.L.1
Wang, G.2
Murphey-Corb, M.3
Wiley, C.A.4
-
57
-
-
0035879076
-
Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death
-
J Katchanov C Harms K Gertz L Hauck C Waeber L Hirt J Priller R von Harsdorf W Bruck H Hortnagl U Dirnagl PG Bhide M Endres 2000 Mild cerebral ischemia induces loss of cyclin-dependent kinase inhibitors and activation of cell cycle machinery before delayed neuronal cell death J Neurosci 2001 21 5045 5053 (Pubitemid 32622930)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.14
, pp. 5045-5053
-
-
Katchanov, J.1
Harms, C.2
Gertz, K.3
Hauck, L.4
Waeber, C.5
Hirt, L.6
Priller, J.7
Von Harsdorf, R.8
Bruck, W.9
Hortnagl, H.10
Dirnagl, U.11
Bhide, P.G.12
Endres, M.13
-
58
-
-
57049177826
-
Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity
-
19081376 1:CAS:528:DC%2BD1cXhsFahs7rE
-
D Kim CL Frank MM Dobbin RK Tsunemoto W Tu PL Peng JS Guan BH Lee LY Moy P Giusti N Broodie R Mazitschek I Delalle SJ Haggarty RL Neve Y Lu LH Tsai 2008 Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity Neuron 60 803 817 19081376 1:CAS:528:DC%2BD1cXhsFahs7rE
-
(2008)
Neuron
, vol.60
, pp. 803-817
-
-
Kim, D.1
Frank, C.L.2
Dobbin, M.M.3
Tsunemoto, R.K.4
Tu, W.5
Peng, P.L.6
Guan, J.S.7
Lee, B.H.8
Moy, L.Y.9
Giusti, P.10
Broodie, N.11
Mazitschek, R.12
Delalle, I.13
Haggarty, S.J.14
Neve, R.L.15
Lu, Y.16
Tsai, L.H.17
-
59
-
-
78751639833
-
6-Hydroxydopamine-induced PC12 cell death is mediated by MEF2D down-regulation
-
21057871
-
MK Kim SC Kim JI Kang JH Hyun HJ Boo SY Eun DB Park ES Yoo HK Kang JH Kang 2011 6-Hydroxydopamine-induced PC12 cell death is mediated by MEF2D down-regulation Neurochem Res 36 223 231 21057871
-
(2011)
Neurochem Res
, vol.36
, pp. 223-231
-
-
Kim, M.K.1
Kim, S.C.2
Kang, J.I.3
Hyun, J.H.4
Boo, H.J.5
Eun, S.Y.6
Park, D.B.7
Yoo, E.S.8
Kang, H.K.9
Kang, J.H.10
-
60
-
-
0037366104
-
Oxidative stress, cell cycle, and neurodegeneration
-
DOI 10.1172/JCI200318182
-
JA Klein SL Ackerman 2003 Oxidative stress, cell cycle, and neurodegeneration J Clin Invest 111 785 793 12639981 1:CAS:528: DC%2BD3sXitlOjsbw%3D (Pubitemid 37074950)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.6
, pp. 785-793
-
-
Klein, J.A.1
Ackerman, S.L.2
-
61
-
-
0037179691
-
The harlequin mouse mutation downregulates apoptosis-inducing factor
-
12353028 1:CAS:528:DC%2BD38XntlGgsb8%3D
-
JA Klein CM Longo-Guess MP Rossmann KL Seburn RE Hurd WN Frankel RT Bronson SL Ackerman 2002 The harlequin mouse mutation downregulates apoptosis-inducing factor Nature 419 367 374 12353028 1:CAS:528: DC%2BD38XntlGgsb8%3D
-
(2002)
Nature
, vol.419
, pp. 367-374
-
-
Klein, J.A.1
Longo-Guess, C.M.2
Rossmann, M.P.3
Seburn, K.L.4
Hurd, R.E.5
Frankel, W.N.6
Bronson, R.T.7
Ackerman, S.L.8
-
62
-
-
0037335443
-
The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons
-
Y Konishi A Bonni 2003 The E2F-Cdc2 cell-cycle pathway specifically mediates activity deprivation-induced apoptosis of postmitotic neurons J Neurosci 23 1649 1658 12629169 1:CAS:528:DC%2BD3sXjtFyltLo%3D (Pubitemid 36314720)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.5
, pp. 1649-1658
-
-
Konishi, Y.1
Bonni, A.2
-
63
-
-
0035112978
-
NF-κB is involved in the survival of cerebellar granule neurons: Association of Iκβ phosphorylation with cell survival
-
DOI 10.1046/j.1471-4159.2001.00134.x
-
E Koulich T Nguyen K Johnson C Giardina S D'mello 2001 NF-kappaB is involved in the survival of cerebellar granule neurons: association of Ikappa β phosphorylation with cell survival J Neurochem 76 1188 1198 11181838 1:CAS:528:DC%2BD3MXhs12nsr8%3D (Pubitemid 32167392)
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.4
, pp. 1188-1198
-
-
Koulich, E.1
Nguyen, T.2
Johnson, K.3
Giardina, C.A.4
D'Mello, S.R.5
-
64
-
-
13244249527
-
Why do neurons enter the cell cycle?
-
II Kruman 2004 Why do neurons enter the cell cycle? Cell Cycle 3 769 773 15136759 1:CAS:528:DC%2BD2MXmtVCmsw%3D%3D (Pubitemid 40187909)
-
(2004)
Cell Cycle
, vol.3
, Issue.6
, pp. 769-773
-
-
Kruman, I.I.1
-
65
-
-
1342333775
-
Cell cycle activation linked to neuronal cell death initiated by DNA damage
-
DOI 10.1016/S0896-6273(04)00017-0
-
II Kruman RP Wersto F Cardozo-Pelaez L Smilenov SL Chan FJ Chrest R Emokpae Jr M Gorospe MP Mattson 2004 Cell cycle activation linked to neuronal cell death initiated by DNA damage Neuron 41 549 561 14980204 1:CAS:528:DC%2BD2cXhvFOrsLg%3D (Pubitemid 38253067)
-
(2004)
Neuron
, vol.41
, Issue.4
, pp. 549-561
-
-
Kruman, I.I.1
Wersto, R.P.2
Cardozo-Pelaez, F.3
Smilenov, L.4
Chan, S.L.5
Chrest, F.J.6
Emokpae Jr., R.7
Gorospe, M.8
Mattson, M.P.9
-
66
-
-
60649083945
-
Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease
-
19114068 1:CAS:528:DC%2BD1MXit1KrtLw%3D
-
HG Lee G Casadesus X Zhu RJ Castellani A McShea G Perry RB Petersen V Bajic MA Smith 2009 Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease Neurochem Int 54 84 88 19114068 1:CAS:528:DC%2BD1MXit1KrtLw%3D
-
(2009)
Neurochem Int
, vol.54
, pp. 84-88
-
-
Lee, H.G.1
Casadesus, G.2
Zhu, X.3
Castellani, R.J.4
McShea, A.5
Perry, G.6
Petersen, R.B.7
Bajic, V.8
Smith, M.A.9
-
67
-
-
78651066554
-
Cyclin D1 immunoreactivity changes in CA1 pyramidal neurons and dentate granule cells in the gerbil hippocampus after transient forebrain ischemia
-
20546683
-
CH Lee KY Yoo JH Choi OK Park IK Hwang SY Choi DH Kim MH Won 2011 Cyclin D1 immunoreactivity changes in CA1 pyramidal neurons and dentate granule cells in the gerbil hippocampus after transient forebrain ischemia Neurol Res 33 93 100 20546683
-
(2011)
Neurol Res
, vol.33
, pp. 93-100
-
-
Lee, C.H.1
Yoo, K.Y.2
Choi, J.H.3
Park, O.K.4
Hwang, I.K.5
Choi, S.Y.6
Kim, D.H.7
Won, M.H.8
-
68
-
-
0242551307
-
Cyclin-dependent kinases in neural development and degeneration
-
AC Lim RZ Qi 2003 Cyclin-dependent kinases in neural development and degeneration J Alzheimers Dis 5 329 335 14624029 1:CAS:528:DC%2BD3sXos1Cls7Y%3D (Pubitemid 37411781)
-
(2003)
Journal of Alzheimer's Disease
, vol.5
, Issue.4
, pp. 329-335
-
-
Lim, A.C.B.1
Qi, R.Z.2
-
69
-
-
0035829650
-
Regulation of neuronal survival and death by E2F-dependent gene repression and derepression
-
DOI 10.1016/S0896-6273(01)00495-0
-
DX Liu LA Greene 2001 Regulation of neuronal survival and death by E2F-dependent gene repression and derepression Neuron 32 425 438 11709154 1:CAS:528:DC%2BD3MXovVehtrY%3D (Pubitemid 33082044)
-
(2001)
Neuron
, vol.32
, Issue.3
, pp. 425-438
-
-
Liu, D.X.1
Greene, L.A.2
-
70
-
-
5444227823
-
B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage
-
DOI 10.1523/JNEUROSCI.1821-04.2004
-
DX Liu SC Biswas LA Greene 2004 B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage J Neurosci 24 8720 8725 15470138 1:CAS:528:DC%2BD2cXovVOltbs%3D (Pubitemid 39362967)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.40
, pp. 8720-8725
-
-
Liu, D.X.1
Biswas, S.C.2
Greene, L.A.3
-
71
-
-
4344594807
-
Apoptosis, autophagy and more
-
15325581 1:CAS:528:DC%2BD2cXmvFemu78%3D
-
RA Lockshin Z Zakari 2004 Apoptosis, autophagy and more Int J Biochem Cell Biol 36 2405 2419 15325581 1:CAS:528:DC%2BD2cXmvFemu78%3D
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2405-2419
-
-
Lockshin, R.A.1
Zakari, Z.2
-
72
-
-
79955109480
-
Cdk5: Multitasking between physiological and pathological conditions
-
21473899 1:CAS:528:DC%2BC3MXmtFeju74%3D
-
JP Lopes P Agostinho 2011 Cdk5: multitasking between physiological and pathological conditions Prog Neurobiol 94 49 63 21473899 1:CAS:528: DC%2BC3MXmtFeju74%3D
-
(2011)
Prog Neurobiol
, vol.94
, pp. 49-63
-
-
Lopes, J.P.1
Agostinho, P.2
-
73
-
-
60749123603
-
Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides
-
19158499 1:CAS:528:DC%2BD1MXlvFSqtrc%3D
-
JP Lopes CR Oliveira P Agostinho 2009 Cdk5 acts as a mediator of neuronal cell cycle re-entry triggered by amyloid-beta and prion peptides Cell Cycle 8 97 104 19158499 1:CAS:528:DC%2BD1MXlvFSqtrc%3D
-
(2009)
Cell Cycle
, vol.8
, pp. 97-104
-
-
Lopes, J.P.1
Oliveira, C.R.2
Agostinho, P.3
-
74
-
-
76249103674
-
Neurodegeneration in an Abeta-induced model of Alzheimer's disease: The role of Cdk5
-
19895631 1:CAS:528:DC%2BC3cXhtlKntrY%3D
-
JP Lopes CR Oliveira P Agostinho 2010 Neurodegeneration in an Abeta-induced model of Alzheimer's disease: the role of Cdk5 Aging Cell 9 64 77 19895631 1:CAS:528:DC%2BC3cXhtlKntrY%3D
-
(2010)
Aging Cell
, vol.9
, pp. 64-77
-
-
Lopes, J.P.1
Oliveira, C.R.2
Agostinho, P.3
-
75
-
-
0344851640
-
Neuronal expression of cell cycle-related proteins after brain ischaemia in man
-
DOI 10.1016/j.neulet.2003.09.004
-
S Love 2003 Neuronal expression of cell cycle-related proteins after brain ischaemia in man Neurosci Lett 353 29 32 14642430 1:CAS:528: DC%2BD3sXpt1ersb0%3D (Pubitemid 37464612)
-
(2003)
Neuroscience Letters
, vol.353
, Issue.1
, pp. 29-32
-
-
Love, S.1
-
76
-
-
0032766155
-
Intrastriatal dopamine injection induces apoptosis through oxidation- involved activation of transcription factors AP-1 and NF-κB in rats
-
Luo Y, Hattori A, Munoz J, Qin ZH, Roth GS (1999) Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats. Mol Pharmacol 56:254-264 (Pubitemid 29347600)
-
(1999)
Molecular Pharmacology
, vol.56
, Issue.2
, pp. 254-264
-
-
Luo, Y.1
Hattori, A.2
Munoz, J.3
Qin, Z.-H.4
Roth, G.S.5
-
77
-
-
0034829801
-
The molecular bases of Alzheimer's disease and other neurodegenerative disorders
-
DOI 10.1016/S0188-4409(01)00316-2, PII S0188440901003162
-
RB Maccioni JP Munoz L Barbeito 2001 The molecular bases of Alzheimer's disease and other neurodegenerative disorders Arch Med Res 32 367 381 11578751 1:CAS:528:DC%2BD3MXnslKhtrk%3D (Pubitemid 32918139)
-
(2001)
Archives of Medical Research
, vol.32
, Issue.5
, pp. 367-381
-
-
Maccioni, R.B.1
Munoz, J.P.2
Barbeito, L.3
-
78
-
-
0033538996
-
Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1
-
JP MacManus CJ Koch M Jian T Walker B Zurakowski 1999 Decreased brain infarct following focal ischemia in mice lacking the transcription factor E2F1 Neuroreport 10 2711 2714 10511428 1:CAS:528:DyaK1MXmsFOnurk%3D (Pubitemid 30004093)
-
(1999)
NeuroReport
, vol.10
, Issue.13
, pp. 2711-2714
-
-
MacManus, J.P.1
Koch, C.J.2
Jian, M.3
Walker, T.4
Zurakowski, B.5
-
81
-
-
9244239811
-
G1 cell-cycle control and cancer
-
DOI 10.1038/nature03094
-
J Massagué 2004 G1 cell-cycle control and cancer Nature 432 298 306 15549091 (Pubitemid 39551657)
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 298-306
-
-
Massague, J.1
-
83
-
-
77953801296
-
Genetic determinants at the interface of cancer and neurodegenerative disease
-
20418918 1:CAS:528:DC%2BC3cXltFKls7g%3D
-
LG Morris S Veeriah TA Chan 2010 Genetic determinants at the interface of cancer and neurodegenerative disease Oncogene 29 3453 34564 20418918 1:CAS:528:DC%2BC3cXltFKls7g%3D
-
(2010)
Oncogene
, vol.29
, pp. 3453-34564
-
-
Morris, L.G.1
Veeriah, S.2
Chan, T.A.3
-
84
-
-
0035968055
-
Up-regulation of E2F-1 in Down's syndrome brain exhibiting neuropathological features of Alzheimer-type dementia
-
DOI 10.1016/S0006-8993(01)02535-5, PII S0006899301025355
-
K Motonaga M Itoh A Hirayama S Hirano LE Becker Y Goto S Takashima 2001 Up-regulation of E2F1 in Down's syndrome brain exhibiting neuropathological features of Alzheimer-type dementia Brain Res 905 250 253 11423103 1:CAS:528:DC%2BD3MXksVyks7g%3D (Pubitemid 32553862)
-
(2001)
Brain Research
, vol.905
, Issue.1-2
, pp. 250-253
-
-
Motonaga, K.1
Itoh, M.2
Hirayama, A.3
Hirano, S.4
Becker, L.E.5
Goto, Y.-I.6
Takashima, S.7
-
85
-
-
0031661968
-
The cell division cycle and the pathophysiology of Alzheimer's disease
-
DOI 10.1016/S0306-4522(98)00293-0, PII S0306452298002930
-
Z Nagy MM Esiri AD Smith 1998 The cell division cycle and the pathophysiology of Alzheimer's disease Neuroscience 87 731 739 9759963 1:CAS:528:DyaK1cXmtVWrs7w%3D (Pubitemid 28400347)
-
(1998)
Neuroscience
, vol.87
, Issue.4
, pp. 731-739
-
-
Nagy, Zs.1
Esiri, M.M.2
Smith, A.D.3
-
86
-
-
85006277004
-
Direct coupling of the cell cycle and cell death machinery by E2F
-
DOI 10.1038/ncb868
-
Z Nahle J Polakoff RV Davuluri ME McCurrach MD Jacobson M Narita MQ Zhang Y Lazebnik D Bar-Sagi SW Lowe 2002 Direct coupling of the cell cycle and cell death machinery by E2F Nat Cell Biol 4 859 864 12389032 1:CAS:528: DC%2BD3sXhtVKmsA%3D%3D (Pubitemid 35331360)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.11
, pp. 859-864
-
-
Nahle, Z.1
Polakoff, J.2
Davuluri, R.V.3
McCurrach, M.E.4
Jacobson, M.D.5
Narita, M.6
Zhang, M.Q.7
Lazebnik, Y.8
Bar-Sagi, D.9
Lowe, S.W.10
-
87
-
-
33745010726
-
Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease
-
DOI 10.1007/s10495-006-6316-3
-
VD Nair 2006 Activation of p53 signaling initiates apoptotic death in a cellular model of Parkinson's disease Apoptosis 11 955 966 16544096 1:CAS:528:DC%2BD28XlsV2ksbw%3D (Pubitemid 43876826)
-
(2006)
Apoptosis
, vol.11
, Issue.6
, pp. 955-966
-
-
Nair, V.D.1
-
88
-
-
33646876851
-
The cell cycle as a therapeutic target for Alzheimer's disease
-
DOI 10.1016/j.pharmthera.2005.09.005, PII S0163725805002081
-
RL Neve DL McPhie 2006 The cell cycle as a therapeutic target for Alzheimer's disease Pharmacol Ther 111 99 113 16274748 1:CAS:528: DC%2BD28XltVekt7Y%3D (Pubitemid 43786202)
-
(2006)
Pharmacology and Therapeutics
, vol.111
, Issue.1
, pp. 99-113
-
-
Neve, R.L.1
McPhie, D.L.2
-
89
-
-
41749088686
-
Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases
-
DOI 10.2174/187152707783399201
-
A Nunomura PI Moreira HG Lee X Zhu RJ Castellani MA Smith G Perry 2007 Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases CNS Neurol Disord Drug Targets 6 411 423 18220780 1:CAS:528: DC%2BD1cXitF2ku78%3D (Pubitemid 351486255)
-
(2007)
CNS and Neurological Disorders - Drug Targets
, vol.6
, Issue.6
, pp. 411-423
-
-
Nunomura, A.1
Moreira, P.I.2
Lee, H.G.3
Zhu, X.4
Castellani, R.J.5
Smith, M.A.6
Perry, G.7
-
91
-
-
0034730122
-
Cyclin-dependent kinases as a therapeutic target for stroke
-
10944192 1:CAS:528:DC%2BD3cXmtlehtL8%3D
-
H Osuga S Osuga F Wang R Fetni MJ Hogan RS Slack AM Hakim JE Ikeda DS Park 2000 Cyclin-dependent kinases as a therapeutic target for stroke Proc Natl Acad Sci USA 97 10254 10259 10944192 1:CAS:528:DC%2BD3cXmtlehtL8%3D
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10254-10259
-
-
Osuga, H.1
Osuga, S.2
Wang, F.3
Fetni, R.4
Hogan, M.J.5
Slack, R.S.6
Hakim, A.M.7
Ikeda, J.E.8
Park, D.S.9
-
92
-
-
67649213878
-
Acetylation status of E2F-1 has an important role in the regulation of E2F-1-mediated transactivation of tumor suppressor p73
-
19523927 1:CAS:528:DC%2BD1MXnvVagurc%3D
-
T Ozaki R Okoshi M Sang N Kubo A Nakagawara 2009 Acetylation status of E2F-1 has an important role in the regulation of E2F-1-mediated transactivation of tumor suppressor p73 Biochem Biophys Res Commun 386 207 211 19523927 1:CAS:528:DC%2BD1MXnvVagurc%3D
-
(2009)
Biochem Biophys Res Commun
, vol.386
, pp. 207-211
-
-
Ozaki, T.1
Okoshi, R.2
Sang, M.3
Kubo, N.4
Nakagawara, A.5
-
93
-
-
0033570320
-
Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis
-
J Padmanabhan DS Park LA Greene ML Shelanski 1999 Role of cell cycle regulatory proteins in cerebellar granule neuron apoptosis J Neurosci 19 8747 8756 10516294 1:CAS:528:DyaK1MXms1ahtL4%3D (Pubitemid 30226696)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.20
, pp. 8747-8756
-
-
Padmanabhan, J.1
Park, D.S.2
Greene, L.A.3
Shelanski, M.L.4
-
94
-
-
77949902091
-
Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B
-
20040599 1:CAS:528:DC%2BC3cXit1ais78%3D
-
JC Paik B Wang K Liu JK Lue WC Lin 2010 Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B J Biol Chem 285 6348 6363 20040599 1:CAS:528:DC%2BC3cXit1ais78%3D
-
(2010)
J Biol Chem
, vol.285
, pp. 6348-6363
-
-
Paik, J.C.1
Wang, B.2
Liu, K.3
Lue, J.K.4
Lin, W.C.5
-
95
-
-
7944234762
-
Flavopiridol: An antitumor drug with potential application in the treatment of neurodegenerative diseases
-
DOI 10.1016/j.mehy.2004.03.047, PII S0306987704003445
-
M Pallas E Verdaguer EG Jorda A Jimenez AM Canudas A Camins 2005 Flavopiridol: an antitumor drug with potential application in the treatment of neurodegenerative diseases Med Hypotheses 64 120 123 15533627 1:CAS:528:DC%2BD2cXpsV2ru7Y%3D (Pubitemid 39469250)
-
(2005)
Medical Hypotheses
, vol.64
, Issue.1
, pp. 120-123
-
-
Pallas, M.1
Verdaguer, E.2
Jorda, E.G.3
Jimenez, A.4
Canudas, A.M.5
Camins, A.6
-
96
-
-
0031016498
-
G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis
-
DS Park EJ Morris LA Greene HM Geller 1997 G1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis J Neurosci 17 1256 1270 9006970 1:CAS:528:DyaK2sXhtVGlurg%3D (Pubitemid 27073728)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.4
, pp. 1256-1270
-
-
Park, D.S.1
Morris, E.J.2
Greene, L.A.3
Geller, H.M.4
-
97
-
-
0031915545
-
Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress
-
DS Park EJ Morris L Stefanis CM Troy ML Shelanski HM Geller LA Greene 1998 Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress J Neurosci 18 830 840 9437005 1:CAS:528:DyaK1cXmtFGguw%3D%3D (Pubitemid 28112906)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.3
, pp. 830-840
-
-
Park, D.S.1
Morris, E.J.2
Stefanis, L.3
Troy, C.M.4
Shelanski, M.L.5
Geller, H.M.6
Greene, L.A.7
-
98
-
-
0033636761
-
Cell cycle regulators in neuronal death evoked by excitotoxic stress: Implications for neurodegeneration and its treatment
-
11124421 1:CAS:528:DC%2BD3cXovFGqu78%3D
-
DS Park A Obeidat A Giovanni LA Greene 2000 Cell cycle regulators in neuronal death evoked by excitotoxic stress: implications for neurodegeneration and its treatment Neurobiol Aging 21 771 871 11124421 1:CAS:528: DC%2BD3cXovFGqu78%3D
-
(2000)
Neurobiol Aging
, vol.21
, pp. 771-871
-
-
Park, D.S.1
Obeidat, A.2
Giovanni, A.3
Greene, L.A.4
-
99
-
-
0033540060
-
Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration
-
GN Patrick L Zukerberg M Nikolic S de la Monte P Dikkes LH Tsai 1999 Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration Nature 402 615 622 10604467 1:CAS:528:DC%2BD3cXjsVGq (Pubitemid 129516324)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 615-622
-
-
Patrick, G.N.1
Zukerberg, L.2
Nikolic, M.3
De La Monte, S.4
Dikkes, P.5
Tsai, L.-H.6
-
100
-
-
0037040934
-
Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29
-
DOI 10.1074/jbc.M109645200
-
H Patzke LH Tsai 2002 Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29 J Biol Chem 277 8054 8060 11784720 1:CAS:528:DC%2BD38XitFymsL0%3D (Pubitemid 34968258)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.10
, pp. 8054-8060
-
-
Patzke, H.1
Tsai, L.-H.2
-
101
-
-
53049106429
-
Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
-
18768156
-
C Pelegrí J Duran-Vilaregut J del Valle N Crespo-Biel I Ferrer M Pallàs A Camins J Vilaplana 2008 Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid Int J Dev Neurosci 26 665 671 18768156
-
(2008)
Int J Dev Neurosci
, vol.26
, pp. 665-671
-
-
Pelegrí, C.1
Duran-Vilaregut, J.2
Del Valle, J.3
Crespo-Biel, N.4
Ferrer, I.5
Pallàs, M.6
Camins, A.7
Vilaplana, J.8
-
102
-
-
0033231615
-
E2F1 potentiates cell death by blocking antiapoptotic signaling pathways
-
10619024 1:CAS:528:DyaK1MXnslOisr0%3D
-
AC Phillips MK Ernst S Bates NR Rice KH Vousden 1999 E2F1 potentiates cell death by blocking antiapoptotic signaling pathways Mol Cell 4 771 781 10619024 1:CAS:528:DyaK1MXnslOisr0%3D
-
(1999)
Mol Cell
, vol.4
, pp. 771-781
-
-
Phillips, A.C.1
Ernst, M.K.2
Bates, S.3
Rice, N.R.4
Vousden, K.H.5
-
103
-
-
77950629978
-
Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells
-
20080185 1:CAS:528:DC%2BC3cXktlCit7o%3D
-
JG Pizarro F Junyent E Verdaguer J Jordan C Beas-Zarate M Pallàs A Camins J Folch 2010 Effects of MPP+ on the molecular pathways involved in cell cycle control in B65 neuroblastoma cells Pharmacol Res 61 391 399 20080185 1:CAS:528:DC%2BC3cXktlCit7o%3D
-
(2010)
Pharmacol Res
, vol.61
, pp. 391-399
-
-
Pizarro, J.G.1
Junyent, F.2
Verdaguer, E.3
Jordan, J.4
Beas-Zarate, C.5
Pallàs, M.6
Camins, A.7
Folch, J.8
-
104
-
-
54049120956
-
E2F - At the crossroads of life and death
-
Polager S, Ginsberg D (2008) E2F - at the crossroads of life and death. Trends Cell Biol 18:528-535
-
(2008)
Trends Cell Biol
, vol.18
, pp. 528-535
-
-
Polager, S.1
Ginsberg, D.2
-
105
-
-
70349437076
-
P53 and E2f: Partners in life and death
-
19776743 1:CAS:528:DC%2BD1MXhtFKmsb%2FO
-
S Polager D Ginsberg 2009 p53 and E2f: partners in life and death Nat Rev Cancer 9 738 748 19776743 1:CAS:528:DC%2BD1MXhtFKmsb%2FO
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 738-748
-
-
Polager, S.1
Ginsberg, D.2
-
106
-
-
49649121765
-
E2F1 regulates autophagy and the transcription of autophagy genes
-
18408756 1:CAS:528:DC%2BD1cXpvVSqtbo%3D
-
S Polager M Ofir D Ginsberg 2008 E2F1 regulates autophagy and the transcription of autophagy genes Oncogene 27 4860 4864 18408756 1:CAS:528:DC%2BD1cXpvVSqtbo%3D
-
(2008)
Oncogene
, vol.27
, pp. 4860-4864
-
-
Polager, S.1
Ofir, M.2
Ginsberg, D.3
-
107
-
-
0038751809
-
Increased DeltaN-p73 expression in tumors by upregulation of the E2F1-regulated, TA-promoter-derived DeltaN'-p73 transcript
-
12728260 1:STN:280:DC%2BD3s3gs1Sksw%3D%3D
-
BM Putzer S Tuve A Tannapfel T Stiewe 2003 Increased DeltaN-p73 expression in tumors by upregulation of the E2F1-regulated, TA-promoter-derived DeltaN'-p73 transcript Cell Death Differ 10 612 624 12728260 1:STN:280:DC%2BD3s3gs1Sksw%3D%3D
-
(2003)
Cell Death Differ
, vol.10
, pp. 612-624
-
-
Putzer, B.M.1
Tuve, S.2
Tannapfel, A.3
Stiewe, T.4
-
108
-
-
0037372292
-
1 to S phase cell-cycle regulators during amyotrophic lateral sclerosis
-
S Ranganathan R Bowser 2003 Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis Am J Pathol 162 823 835 12598317 1:CAS:528:DC%2BD3sXit1GksL8%3D (Pubitemid 36237491)
-
(2003)
American Journal of Pathology
, vol.162
, Issue.3
, pp. 823-835
-
-
Ranganathan, S.1
Bowser, R.2
-
109
-
-
84860428058
-
P53 and cell cycle proteins participate in spinal motor neuron cell death in ALS
-
21572928 1:CAS:528:DC%2BC3cXls1Kjsrc%3D
-
S Ranganathan R Bowser 2010 p53 and cell cycle proteins participate in spinal motor neuron cell death in ALS Open Pathol J 4 11 22 21572928 1:CAS:528:DC%2BC3cXls1Kjsrc%3D
-
(2010)
Open Pathol J
, vol.4
, pp. 11-22
-
-
Ranganathan, S.1
Bowser, R.2
-
110
-
-
25444460165
-
Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo
-
DOI 10.1073/pnas.0500099102
-
J Rashidian G Iyirhiaro H Aleyasin M Rios I Vincent S Callaghan RJ Bland RS Slack MJ During DS Park 2005 Multiple cyclin-dependent kinases signals are critical mediators of ischemia/hypoxic neuronal death in vitro and in vivo Proc Natl Acad Sci USA 102 14080 14085 16166266 1:CAS:528:DC%2BD2MXhtVOqsbbF (Pubitemid 41377706)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.39
, pp. 14080-14085
-
-
Rashidian, J.1
Iyirhiaro, G.2
Aleyasin, H.3
Rios, M.4
Vincent, I.5
Callaghan, S.6
Bland, R.J.7
Slack, R.S.8
During, M.J.9
Park, D.S.10
-
112
-
-
1842576577
-
Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity
-
DOI 10.1016/j.nbd.2003.11.003, PII S0969996103002407
-
K Sakai Y Kitagawa S Saiki M Saiki G Hirose 2004 Effect of a paraneoplastic cerebellar degeneration-associated neural protein on B-myb promoter activity Neurobiol Dis 15 529 533 15056460 1:CAS:528: DC%2BD2cXivVKnu7g%3D (Pubitemid 38429967)
-
(2004)
Neurobiology of Disease
, vol.15
, Issue.3
, pp. 529-533
-
-
Sakai, K.1
Kitagawa, Y.2
Saiki, S.3
Saiki, M.4
Hirose, G.5
-
113
-
-
30844469526
-
short
-
DOI 10.1038/sj.cdd.4401739, PII 4401739
-
C Salon B Eymin O Micheau L Chaperot J Plumas C Brambilla E Brambilla S Gazzeri 2006 E2F1 induces apoptosis and sensitizes human lung adenocarcinoma cells to death-receptor-mediated apoptosis through specific downregulation of c-FLIP(short) Cell Death Differ 13 260 272 16052233 1:CAS:528: DC%2BD28XjtVyrtg%3D%3D (Pubitemid 43102209)
-
(2006)
Cell Death and Differentiation
, vol.13
, Issue.2
, pp. 260-272
-
-
Salon, C.1
Eymin, B.2
Micheau, O.3
Chaperot, L.4
Plumas, J.5
Brambilla, C.6
Brambilla, E.7
Gazzeri, S.8
-
114
-
-
34547689195
-
Constitutive expression of functionally active cyclin-dependent kinases and their binding partners suggests noncanonical functions of cell cycle regulators in differentiated neurons
-
DOI 10.1093/cercor/bhl091
-
S Schmetsdorf U Gärtner T Arendt 2007 Constitutive expression of functionally active cyclin-dependent kinases and their binding partners suggests noncanonical functions of cell cycle regulators in differentiated neurons Cereb Cortex 17 1821 1829 17050646 (Pubitemid 47216499)
-
(2007)
Cerebral Cortex
, vol.17
, Issue.8
, pp. 1821-1829
-
-
Schmetsdorf, S.1
Gartner, U.2
Arendt, T.3
-
115
-
-
61849146919
-
A putative role for cell cycle-related proteins in microtubule-based neuroplasticity
-
19302146
-
S Schmetsdorf E Arnold M Holzer T Arendt U Gärtner 2009 A putative role for cell cycle-related proteins in microtubule-based neuroplasticity Eur J Neurosci 29 1096 1107 19302146
-
(2009)
Eur J Neurosci
, vol.29
, pp. 1096-1107
-
-
Schmetsdorf, S.1
Arnold, E.2
Holzer, M.3
Arendt, T.4
Gärtner, U.5
-
116
-
-
33847018111
-
Cell cycle activation in postmitotic neurons is essential for DNA repair
-
17297309 1:CAS:528:DC%2BD2sXnvFygtL0%3D
-
EI Schwartz LB Smilenov MA Price T Osredkar RA Baker S Ghosh FD Shi TL Vollmer A Lencinas DM Stearns M Gorospe II Kruman 2007 Cell cycle activation in postmitotic neurons is essential for DNA repair Cell Cycle 6 318 329 17297309 1:CAS:528:DC%2BD2sXnvFygtL0%3D
-
(2007)
Cell Cycle
, vol.6
, pp. 318-329
-
-
Schwartz, E.I.1
Smilenov, L.B.2
Price, M.A.3
Osredkar, T.4
Baker, R.A.5
Ghosh, S.6
Shi, F.D.7
Vollmer, T.L.8
Lencinas, A.9
Stearns, D.M.10
Gorospe, M.11
Kruman, I.I.12
-
117
-
-
0344823864
-
Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease
-
DOI 10.1073/pnas.2232515100
-
PD Smith SJ Crocker V Jackson-Lewis KL Jordan-Sciutto S Hayley MP Mount MJ O'Hare S Callaghan RS Slack S Przedborski H Anisman DS Park 2003 Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease Proc Natl Acad Sci USA 100 13650 13655 14595022 1:CAS:528:DC%2BD3sXptFOitbo%3D (Pubitemid 37444794)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.23
, pp. 13650-13655
-
-
Smith, P.D.1
Crocker, S.J.2
Jackson-Lewis, V.3
Jordan-Sciutto, K.L.4
Hayley, S.5
Mount, M.P.6
O'Hare, M.J.7
Callaghan, S.8
Slack, R.S.9
Przedborski, S.10
Anisman, H.11
Park, D.S.12
-
118
-
-
0042020021
-
Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells
-
DOI 10.1016/S0169-328X(03)00253-5
-
RA Smith T Walker X Xie ST Hou 2003 Involvement of the transcription factor E2F1/Rb in kainic acid-induced death of murine cerebellar granule cells Brain Res Mol Brain Res 116 70 79 12941462 1:CAS:528:DC%2BD3sXms1ylsbY%3D (Pubitemid 36993698)
-
(2003)
Molecular Brain Research
, vol.116
, Issue.1-2
, pp. 70-79
-
-
Smith, R.A.1
Walker, T.2
Xie, X.3
Hou, S.T.4
-
119
-
-
16544361999
-
Emerging pathogenic role for cyclin dependent kinases in neurodegeneration
-
PD Smith MJ O'Hare DS Park 2004 Emerging pathogenic role for cyclin dependent kinases in neurodegeneration Cell Cycle 3 289 291 14726693 1:CAS:528:DC%2BD2cXltFKrtrg%3D (Pubitemid 41359077)
-
(2004)
Cell Cycle
, vol.3
, Issue.3
, pp. 289-291
-
-
Smith, P.D.1
O'Hare, M.J.2
Park, D.S.3
-
120
-
-
33646047403
-
E2F1-induced apoptosis: Turning killers into therapeutics
-
16530485 1:CAS:528:DC%2BD28XjvFWltr0%3D
-
J Stanelle BM Putzer 2006 E2F1-induced apoptosis: turning killers into therapeutics Trends Mol Med 12 177 185 16530485 1:CAS:528:DC%2BD28XjvFWltr0%3D
-
(2006)
Trends Mol Med
, vol.12
, pp. 177-185
-
-
Stanelle, J.1
Putzer, B.M.2
-
121
-
-
17144371344
-
A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53
-
DOI 10.1038/sj.cdd.4401532
-
J Stanelle H Tu-Rapp BM Putzer 2005 A novel mitochondrial protein DIP mediates E2F1-induced apoptosis independently of p53 Cell Death Differ 12 347 357 15565177 1:CAS:528:DC%2BD2MXitlCms7k%3D (Pubitemid 40520686)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.4
, pp. 347-357
-
-
Stanelle, J.1
Tu-Rapp, H.2
Putzer, B.M.3
-
122
-
-
27644472289
-
E2F1 induces cell death, calpain activation, and MDMX degradation in a transcription independent manner implicating a novel role for E2F1 in neuronal loss in SIV encephalitis
-
DOI 10.1002/jcb.20574
-
GD Strachan MA Koike R Siman DJ Hall KL Jordan-Sciutto 2005 E2F1 induces cell death, calpain activation, and MDMX degradation in a transcription independent manner implicating a novel role for E2F1 in neuronal loss in SIV encephalitis J Cell Biochem 96 728 740 16088944 1:CAS:528:DC%2BD2MXhtFyhsLnM (Pubitemid 41567544)
-
(2005)
Journal of Cellular Biochemistry
, vol.96
, Issue.4
, pp. 728-740
-
-
Strachan, G.D.1
Koike, M.A.2
Siman, R.3
Hall, D.J.4
Jordan-Sciutto, K.L.5
-
123
-
-
51849133140
-
Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction
-
18691386 1:CAS:528:DC%2BD1cXht1Kgtb%2FN
-
KH Sun Y de Pablo F Vincent K Shah 2008 Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction J Neurochem 107 265 278 18691386 1:CAS:528:DC%2BD1cXht1Kgtb%2FN
-
(2008)
J Neurochem
, vol.107
, pp. 265-278
-
-
Sun, K.H.1
De Pablo, Y.2
Vincent, F.3
Shah, K.4
-
124
-
-
73949151138
-
Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: Relevance to neurotoxic insults in Alzheimer's disease
-
KH Sun HG Lee MA Smith K Shah 2009 Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease Mol Biol Cell 2021 4611 4619
-
(2009)
Mol Biol Cell
, vol.2021
, pp. 4611-4619
-
-
Sun, K.H.1
Lee, H.G.2
Smith, M.A.3
Shah, K.4
-
126
-
-
0027978170
-
P35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5
-
DOI 10.1038/371419a0
-
Tsai LH, Delalle I, Caviness VS Jr, Chae T, Harlow E (1994) p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature 371(6496):419-423 (Pubitemid 24302556)
-
(1994)
Nature
, vol.371
, Issue.6496
, pp. 419-423
-
-
Teai, L.-H.1
Delalle, I.2
Cavness Jr., V.S.3
Chae, T.4
Harlow, E.5
-
128
-
-
19944386244
-
The expression of cell cycle proteins in neurons and its relevance for Alzheimer's disease
-
DOI 10.2174/1568007054038175
-
U Ueberham T Arendt 2005 The expression of cell cycle proteins in neurons and its relevance for Alzheimer's disease Curr Drug Targets CNS Neurol Disord 4 293 306 15975031 1:CAS:528:DC%2BD2MXkvF2ls7k%3D (Pubitemid 40754164)
-
(2005)
Current Drug Targets: CNS and Neurological Disorders
, vol.4
, Issue.3
, pp. 293-306
-
-
Ueberham, U.1
Arendt, T.2
-
129
-
-
77953553525
-
The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin e
-
20372088 1:CAS:528:DC%2BC3cXht12qs7fM
-
S Veeriah L Morris D Solit TA Chan 2010 The familial Parkinson disease gene PARK2 is a multisite tumor suppressor on chromosome 6q25.2-27 that regulates cyclin E Cell Cycle 9 1451 1452 20372088 1:CAS:528:DC%2BC3cXht12qs7fM
-
(2010)
Cell Cycle
, vol.9
, pp. 1451-1452
-
-
Veeriah, S.1
Morris, L.2
Solit, D.3
Chan, T.A.4
-
130
-
-
0037171105
-
Kainic acid-induced apoptosis in cerebellar granule neurons: An attempt at cell cycle re-entry
-
E Verdaguer E Garcia-Jorda AM Canudas E Dominguez A Jimenez D Pubill E Escubedo J Camarasa M Pallas A Camins 2002 Kainic acid-induced apoptosis in cerebellar granule neurons: an attempt at cell cycle re-entry Neuroreport 13 413 416 11930151 1:CAS:528:DC%2BD38XnsFKkurk%3D (Pubitemid 34293180)
-
(2002)
NeuroReport
, vol.13
, Issue.4
, pp. 413-416
-
-
Verdaguer, E.1
Garcia-Jorda, E.2
Canudas, A.M.3
Dominguez, E.4
Jimenez, A.5
Pubill, D.6
Escubedo, E.7
Pallas, J.C.M.8
Camins, A.9
-
131
-
-
1642538995
-
Inhibition of Cell Cycle Pathway by Flavopiridol Promotes Survival of Cerebellar Granule Cells after an Excitotoxic Treatment
-
DOI 10.1124/jpet.103.057497
-
E Verdaguer A Jimenez AM Canudas EG Jorda FX Sureda M Pallas A Camins 2004 Inhibition of cell cycle pathway by flavopiridol promotes survival of cerebellar granule cells after an excitotoxic treatment J Pharmacol Exp Ther 308 609 616 14610234 1:CAS:528:DC%2BD2cXhtlSquro%3D (Pubitemid 38134223)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.308
, Issue.2
, pp. 609-616
-
-
Verdaguer, E.1
Jimenez, A.2
Canudas, A.M.3
Jorda, E.G.4
Sureda, F.X.5
Pallas, M.6
Camins, A.7
-
132
-
-
22344449621
-
Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons
-
DOI 10.1385/JMN:26:03:71
-
E Verdaguer EG Jorda D Alvira A Jimenez AM Canudas J Folch V Rimbau M Pallas A Camins 2005 Inhibition of multiple pathways accounts for the antiapoptotic effects of flavopiridol on potassium withdrawal-induced apoptosis in neurons J Mol Neurosci 26 71 84 15968087 1:CAS:528:DC%2BD2MXmsVaku70%3D (Pubitemid 41003428)
-
(2005)
Journal of Molecular Neuroscience
, vol.26
, Issue.1
, pp. 71-84
-
-
Verdaguer, E.1
Jorda, E.G.2
Alvira, D.3
Jimenez, A.4
Canudas, A.M.5
Folch, J.6
Rimbau, V.7
Pallas, M.8
Camins, A.9
-
133
-
-
0030062245
-
Mitotic mechanisms in Alzheimer's disease?
-
DOI 10.1083/jcb.132.3.413
-
I Vincent M Rosado P Davies 1996 Mitotic mechanisms in Alzheimer's disease? J Cell Biol 132 413 425 8636218 1:CAS:528:DyaK28XpsVejtw%3D%3D (Pubitemid 26053445)
-
(1996)
Journal of Cell Biology
, vol.132
, Issue.3
, pp. 413-425
-
-
Vincent, I.1
Rosado, M.2
Davies, P.3
-
134
-
-
63849135934
-
Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661 W cells and the retina
-
18951482 1:CAS:528:DC%2BD1MXivVamtLk%3D
-
DM Wallace TG Cotter 2009 Histone deacetylase activity in conjunction with E2F-1 and p53 regulates Apaf-1 expression in 661 W cells and the retina J Neurosci Res 87 887 905 18951482 1:CAS:528:DC%2BD1MXivVamtLk%3D
-
(2009)
J Neurosci Res
, vol.87
, pp. 887-905
-
-
Wallace, D.M.1
Cotter, T.G.2
-
135
-
-
0036167643
-
Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat
-
F Wang D Corbett H Osuga S Osuga JE Ikeda RS Slack MJ Hogan AM Hakim DS Park 2002 Inhibition of cyclin-dependent kinases improves CA1 neuronal survival and behavioral performance after global ischemia in the rat J Cereb Blood Flow Metab 22 171 182 11823715 1:CAS:528:DC%2BD38XhsVKrs74%3D (Pubitemid 34135648)
-
(2002)
Journal of Cerebral Blood Flow and Metabolism
, vol.22
, Issue.2
, pp. 171-182
-
-
Wang, F.1
Corbett, D.2
Osuga, H.3
Osuga, S.4
Ikeda, J.-E.5
Slack, R.S.6
Hogan, M.J.7
Hakim, A.M.8
Park, D.S.9
-
136
-
-
11144241301
-
A role for 14-3-3τ in E2F1 stabilization and DNA damage-induced apoptosis
-
DOI 10.1074/jbc.M410493200
-
B Wang K Liu FT Lin WC Lin 2004 A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis J Biol Chem 279 54140 54152 15494392 1:CAS:528:DC%2BD2cXhtVyltb7M (Pubitemid 40053150)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54140-54152
-
-
Wang, B.1
Liu, K.2
Lin, F.-T.3
Lin, W.-C.4
-
137
-
-
24344476294
-
The cell cycle in Alzheimer disease: A unique target for neuropharmacology
-
DOI 10.1016/j.mad.2005.03.024, PII S004763740500103X
-
KM Webber AK Raina MW Marlatt X Zhu MI Prat L Morelli G Casadesus G Perry MA Smith 2005 The cell cycle in Alzheimer disease: a unique target for neuropharmacology Mech Ageing Dev 126 1019 1025 15936057 1:CAS:528: DC%2BD2MXpvFeisbs%3D (Pubitemid 41253852)
-
(2005)
Mechanisms of Ageing and Development
, vol.126
, Issue.10
, pp. 1019-1025
-
-
Webber, K.M.1
Raina, A.K.2
Marlatt, M.W.3
Zhu, X.4
Prat, M.I.5
Morelli, L.6
Casadesus, G.7
Perry, G.8
Smith, M.A.9
-
138
-
-
24044481621
-
Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats
-
DOI 10.1016/j.febslet.2005.07.028, PII S0014579305008719
-
Y Wen S Yang R Liu JW Simpkins 2005 Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats FEBS Lett 579 4591 4599 16098510 1:CAS:528:DC%2BD2MXpt1eku7c%3D (Pubitemid 41218632)
-
(2005)
FEBS Letters
, vol.579
, Issue.21
, pp. 4591-4599
-
-
Wen, Y.1
Yang, S.2
Liu, R.3
Simpkins, J.W.4
-
139
-
-
8844263102
-
Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo
-
DOI 10.1016/j.molbrainres.2004.08.020, PII S0169328X04004176
-
R Wu Chen Y Zhang ME Rose SH Graham 2004 Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo Brain Res Mol Brain Res 132 31 37 15548426 (Pubitemid 39531349)
-
(2004)
Molecular Brain Research
, vol.132
, Issue.1
, pp. 31-37
-
-
Wu Chen, R.1
Zhang, Y.2
Rose, M.E.3
Graham, S.H.4
-
140
-
-
33645925293
-
Novel link between E2F1 and Smac/DIABLO: Proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1
-
16617145 1:CAS:528:DC%2BD28Xks1SltLw%3D
-
W Xie P Jiang L Miao Y Zhao Z Zhimin L Qing WG Zhu M Wu 2006 Novel link between E2F1 and Smac/DIABLO: proapoptotic Smac/DIABLO is transcriptionally upregulated by E2F1 Nucleic Acids Res 34 2046 2255 16617145 1:CAS:528: DC%2BD28Xks1SltLw%3D
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 2046-2255
-
-
Xie, W.1
Jiang, P.2
Miao, L.3
Zhao, Y.4
Zhimin, Z.5
Qing, L.6
Zhu, W.G.7
Wu, M.8
-
141
-
-
0035871660
-
DNA replication precedes neuronal cell death in Alzheimer's disease
-
Y Yang DS Geldmacher K Herrup 2001 DNA replication precedes neuronal cell death in Alzheimer's disease J Neurosci 21 2661 2668 11306619 1:CAS:528:DC%2BD3MXjtVWku7s%3D (Pubitemid 32298208)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.8
, pp. 2661-2668
-
-
Yang, Y.1
Geldmacher, D.S.2
Herrup, K.3
-
142
-
-
0344241479
-
Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease
-
Y Yang EJ Mufson K Herrup 2003 Neuronal cell death is preceded by cell cycle events at all stages of Alzheimer's disease J Neurosci 23 2557 2563 12684440 1:CAS:528:DC%2BD3sXjtFCnsbg%3D (Pubitemid 36418589)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.7
, pp. 2557-2563
-
-
Yang, Y.1
Mufson, E.J.2
Herrup, K.3
-
143
-
-
24644489720
-
DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells
-
Yu X, Caltagarone J, Smith MA, Bowser R (2005) DNA damage induces cdk2 protein levels and histone H2B phosphorylation in SH-SY5Y neuroblastoma cells. J Alzheimers Dis 8:7-21 (Pubitemid 41267319)
-
(2005)
Journal of Alzheimer's Disease
, vol.8
, Issue.1
, pp. 7-21
-
-
Yu, X.1
Caltagarone, J.2
Smith, M.A.3
Bowser, R.4
-
144
-
-
4344637728
-
Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice
-
M Zhang J Li P Chakrabarty B Bu I Vincent 2004 Cyclin-dependent kinase inhibitors attenuate protein hyperphosphorylation, cytoskeletal lesion formation, and motor defects in Niemann-Pick Type C mice Am J Pathol 165 843 853 15331409 1:CAS:528:DC%2BD2cXnvFKitrs%3D (Pubitemid 39129292)
-
(2004)
American Journal of Pathology
, vol.165
, Issue.3
, pp. 843-853
-
-
Zhang, M.1
Li, J.2
Chakrabarty, P.3
Bu, B.4
Vincent, I.5
-
145
-
-
0034797352
-
Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: The 'two hit' hypothesis
-
DOI 10.1016/S0047-6374(01)00342-6, PII S0047637401003426
-
X Zhu RJ Castellani A Takeda A Nunomura CS Atwood G Perry MA Smith 2001 Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis Mech Ageing Dev 123 39 46 11640950 1:CAS:528: DC%2BD3MXnsF2hurc%3D (Pubitemid 32972257)
-
(2001)
Mechanisms of Ageing and Development
, vol.123
, Issue.1
, pp. 39-46
-
-
Zhu, X.1
Castellani, R.J.2
Takeda, A.3
Nunomura, A.4
Atwood, C.S.5
Perry, G.6
Smith, M.A.7
-
146
-
-
1642358352
-
Alzheimer's disease: The two-hit hypothesis
-
DOI 10.1016/S1474-4422(04)00707-0, PII S1474442204007070
-
X Zhu AK Raina G Perry MA Smith 2004 Alzheimer's disease: the two-hit hypothesis Lancet Neurol 3 219 226 15039034 1:CAS:528:DC%2BD2cXjvFyisbo%3D (Pubitemid 38373660)
-
(2004)
Lancet Neurology
, vol.3
, Issue.4
, pp. 219-226
-
-
Zhu, X.1
Raina, A.K.2
Perry, G.3
Smith, M.A.4
-
147
-
-
33947178563
-
Alzheimer disease, the two-hit hypothesis: An update
-
DOI 10.1016/j.bbadis.2006.10.014, PII S0925443906002304
-
X Zhu HG Lee G Perry MA Smith 2007 Alzheimer disease, the two-hit hypothesis: an update Biochim Biophys Acta 1772 494 502 17142016 1:CAS:528:DC%2BD2sXjtVahu70%3D (Pubitemid 46400383)
-
(2007)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1772
, Issue.4
, pp. 494-502
-
-
Zhu, X.1
Lee, H.-g.2
Perry, G.3
Smith, M.A.4
-
148
-
-
80053107856
-
Cdk5: Mediator of neuronal development, death and the response to DNA damage
-
May 11. [Epub ahead of print]
-
Zhu J, Li W, Mao Z. (2011) Cdk5: Mediator of neuronal development, death and the response to DNA damage. Mech Ageing Dev. May 11. [Epub ahead of print]
-
(2011)
Mech Ageing Dev.
-
-
Zhu, J.1
Li, W.2
Mao, Z.3
|