The pRb/E2F cell-cycle pathway mediates cell death in Parkinson's disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 9, 2007, Pages 3585-3590

  Höglinger, Günter U ^a,b,c   Breunig, Joshua J ^d   Depboylu, Candan ^a   Rouaux, Caroline ^b   Michel, Patrick P ^a,b   Alvarez Fischer, Daniel ^a   Boutillier, Anne Laurence ^b   DeGregori, James ^e   Oertel, Wolfgang H ^a   Rakic, Pasko ^d   Hirsch, Etienne C ^a,b   Hunot, Stéphane ^a,b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b INSERM   (France)

^c SORBONNE UNIVERSITÉ   (France)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Adult neurogenesis; Apoptosis; Dopamine; Neurodegeneration; Retinoblastoma

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; 1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; BROXURIDINE; CELL NUCLEUS DNA; NEUROTOXIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR E2F1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIVISION; CONTROLLED STUDY; DNA REPLICATION; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN TISSUE; MALE; MESENCEPHALON; MITOSIS; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INTERNEURONS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OLIGONUCLEOTIDES, ANTISENSE; PARKINSON DISEASE; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

MUS;

EID: 33847610595     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0611671104     Document Type: Article

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