Cdk5 is a major regulator of p38 cascade: Relevance to neurotoxicity in Alzheimer's disease

Journal of Neurochemistry

Volumn 113, Issue 5, 2010, Pages 1221-1229

  Chang, Kuei Hua ^a   De Pablo, Yolanda ^a   Lee, Hyun Pil ^b   Lee, Hyoung Gon ^b   Smith, Mark A ^b   Shah, Kavita ^a  

^a PURDUE UNIVERSITY   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; C Jun; Cdk5; Oxidative stress; P38

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; GLUTAMIC ACID; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; SYNAPTOPHYSIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CALPAIN; COLORING AGENTS; CYCLIN-DEPENDENT KINASE 5; GLUTAMIC ACID; HUMANS; IMMUNOHISTOCHEMISTRY; MAP KINASE KINASE 6; MICE; MICE, TRANSGENIC; NEURONS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TETRAZOLIUM SALTS; THIAZOLES;

MUS MUSCULUS;

EID: 77951932919     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06687.x     Document Type: Article

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