From abnormal hippocampal synaptic plasticity in down syndrome mouse models to cognitive disability in down syndrome

Neural Plasticity

Volumn 2012, Issue , 2012, Pages

  Cramer, Nathan ^a   Galdzicki, Zygmunt ^a  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID B RECEPTOR BLOCKING AGENT; AMPA RECEPTOR; BILOBALIDE; BRAIN DERIVED NEUROTROPHIC FACTOR; CALCINEURIN; CALCINEURIN INHIBITOR; CALCIUM; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CYCLIC AMP DEPENDENT PROTEIN KINASE; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL 2; MAMMALIAN TARGET OF RAPAMYCIN; MEMANTINE; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; OLIG1 PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; PENTETRAZOLE; PICROTOXIN; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE B; RCAN1 PROTEIN; REGULATOR PROTEIN; RG 1662; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ADAPTATION; ALZHEIMER DISEASE; BEHAVIOR THERAPY; BRAIN CORTEX; CALCIUM CELL LEVEL; CELL PROLIFERATION; CELL STRUCTURE; CLINICAL RESEARCH; COGNITION; COGNITIVE DEFECT; DEMENTIA; DENDRITE; DISEASE ASSOCIATION; DOWN SYNDROME; DRUG EFFICACY; DRUG SAFETY; DRUG TARGETING; EXCITATORY JUNCTION POTENTIAL; FACILITATION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE DELETION; GENE DOSAGE; GENE EXPRESSION; GENE OVEREXPRESSION; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; LONG TERM DEPRESSION; LONG TERM POTENTIATION; LOW DRUG DOSE; MOSAICISM; MOUSE; MOUSE STRAIN; NERVE CELL; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NEUROIMAGING; NEUROPATHOLOGY; NEUROPHYSIOLOGY; NONHUMAN; POSTSYNAPTIC DENSITY; PROTEIN BLOOD LEVEL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; REVIEW; RISK FACTOR; SHORT TERM MEMORY; SIGNAL TRANSDUCTION; SYNAPSE; SYNAPTIC TRANSMISSION; SYNAPTOGENESIS; TRISOMY; ANIMAL; BIOLOGICAL MODEL; COGNITIVE THERAPY; HUMAN; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGICAL ASPECT;

ANIMALS; COGNITION DISORDERS; COGNITIVE THERAPY; DOWN SYNDROME; HIPPOCAMPUS; HUMANS; MICE; MODELS, NEUROLOGICAL; NEURONAL PLASTICITY; SIGNAL TRANSDUCTION; SYNAPSES;

EID: 84864932030     PISSN: 20905904     EISSN: 16875443     Source Type: Journal    
DOI: 10.1155/2012/101542     Document Type: Review

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