Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome

Brain Pathology

Volumn 18, Issue 2, 2008, Pages 180-197

  Guidi, Sandra ^a   Bonasoni, Paola ^b   Ceccarelli, Claudio ^b   Santini, Donatella ^b   Gualtieri, Fabio ^a   Ciani, Elisabetta ^a   Bartesaghi, Renata ^a,c  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c Dipartimento di Fisiologia Umana e Generale   (Italy)

Author keywords

Dentate gyrus; Hippocampus; Mental retardation; Neurogenesis; Trisomy 21

Indexed keywords

KI 67 ANTIGEN;

APOPTOSIS; ARTICLE; ASTROCYTE; BODY WEIGHT; CELL COUNT; CELL CYCLE; CELL DEATH; CELL PROLIFERATION; CELL VOLUME; CLINICAL ARTICLE; CONTROLLED STUDY; CROWN RUMP LENGTH; DOWN SYNDROME; FEMALE; FETUS; GESTATIONAL AGE; HIPPOCAMPUS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVOUS SYSTEM DEVELOPMENT; NEUROPATHOLOGY; PHENOTYPE; SUBICULUM;

BODY WEIGHT; CASE-CONTROL STUDIES; CASPASE 3; CELL COUNT; CELL DEATH; CELL DIFFERENTIATION; CELL PROLIFERATION; DOWN SYNDROME; FEMALE; FETUS; GLIAL FIBRILLARY ACIDIC PROTEIN; HIPPOCAMPUS; HUMANS; INFANT; KI-67 ANTIGEN; MALE; NEURONS; PHOSPHOPYRUVATE HYDRATASE;

EID: 41149164894     PISSN: 10156305     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2007.00113.x     Document Type: Article

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