메뉴 건너뛰기




Volumn 138, Issue 2, 2003, Pages 121-131

Behavioral comparison of 4 and 6 month-old Ts65Dn mice: Age-related impairments in working and reference memory

Author keywords

Down's syndrome; Radial arm maze; Reference memory; Ts65Dn; Working memory; Working memory load

Indexed keywords

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CHOLINERGIC SYSTEM; COGNITION; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; LEARNING; MALE; MAZE TEST; MEMORY DISORDER; MOUSE; NONHUMAN; PRIORITY JOURNAL; TASK PERFORMANCE; WORKING MEMORY;

EID: 0037460101     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(02)00275-9     Document Type: Article
Times cited : (98)

References (40)
  • 1
    • 0033978891 scopus 로고    scopus 로고
    • Discovery and genetic localization of Down Syndrome cerebellar phenotypes using the Ts65Dn mouse
    • Baxter L.L., Moran T.H., Richtmeier J.T., Troncoso J., Reeves R.H. Discovery and genetic localization of Down Syndrome cerebellar phenotypes using the Ts65Dn mouse. Hum. Mol. Genet. 9:(2):2000;195-202.
    • (2000) Hum. Mol. Genet. , vol.9 , Issue.2 , pp. 195-202
    • Baxter, L.L.1    Moran, T.H.2    Richtmeier, J.T.3    Troncoso, J.4    Reeves, R.H.5
  • 2
    • 0344490570 scopus 로고    scopus 로고
    • Frontal cortex BDNF levels correlate with working memory in an animal model of Down's Syndrome
    • in press
    • Bimonte HA, Hunter CL, Nelson ME, Granholm Ach. Frontal cortex BDNF levels correlate with working memory in an animal model of Down's Syndrome, Behav Brain Res 2002; in press.
    • (2002) Behav Brain Res
    • Bimonte, H.A.1    Hunter, C.L.2    Nelson, M.E.3    Granholm, A.4
  • 3
    • 0033826237 scopus 로고    scopus 로고
    • In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze
    • Bimonte H., Hyde L., Hoplight B., Denenberg V. In two species, females exhibit superior working memory and inferior reference memory on the water radial-arm maze. Physiol. Behav. 70:2000;311-317.
    • (2000) Physiol. Behav. , vol.70 , pp. 311-317
    • Bimonte, H.1    Hyde, L.2    Hoplight, B.3    Denenberg, V.4
  • 4
    • 0005760032 scopus 로고    scopus 로고
    • Age-related deficits as working memory load increases: Relationships with growth factors
    • in press
    • Bimonte HA, Nelson ME, Granholm Ach. Age-related deficits as working memory load increases: relationships with growth factors, Neurobiol Aging 2002; in press.
    • (2002) Neurobiol Aging
    • Bimonte, H.A.1    Nelson, M.E.2    Granholm, A.3
  • 7
    • 0033407499 scopus 로고    scopus 로고
    • Motor dysfunction in a mouse model for Down syndrome
    • Costa A.C.S., Walsh K., Davisson M.T. Motor dysfunction in a mouse model for Down syndrome. Physiol. Behav. 68:1999;211-220.
    • (1999) Physiol. Behav. , vol.68 , pp. 211-220
    • Costa, A.C.S.1    Walsh, K.2    Davisson, M.T.3
  • 8
    • 0030045921 scopus 로고    scopus 로고
    • Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: Altered behavior in the elevated plus maze and open field
    • Coussons-Read M.E., Crinic L.S. Behavioral assessment of the Ts65Dn mouse, a model for Down syndrome: altered behavior in the elevated plus maze and open field. Behav. Genet. 26:(1):1996;7-13.
    • (1996) Behav. Genet. , vol.26 , Issue.1 , pp. 7-13
    • Coussons-Read, M.E.1    Crinic, L.S.2
  • 9
    • 0003043137 scopus 로고    scopus 로고
    • Contributions of mouse models to understanding Down's syndrome
    • Crnic L.S., Pennington B.F. Contributions of mouse models to understanding Down's syndrome. Prog. Infancy Res. 1:2000;69-111.
    • (2000) Prog. Infancy Res. , vol.1 , pp. 69-111
    • Crnic, L.S.1    Pennington, B.F.2
  • 10
    • 0025663975 scopus 로고
    • Segmental trisomy of murine chromosome 16: A new model system for studying Down syndrome
    • Davisson M.T., Schmidt C., Akeson E.C. Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome. Prog. Clin. Biol. Res. 360:1990;263-280.
    • (1990) Prog. Clin. Biol. Res. , vol.360 , pp. 263-280
    • Davisson, M.T.1    Schmidt, C.2    Akeson, E.C.3
  • 12
    • 0031890117 scopus 로고    scopus 로고
    • Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice
    • Demas G.E., Nelson R.J., Krueger B.K., Yarowsky P.J. Impaired spatial working and reference memory in segmental trisomy (Ts65Dn) mice. Behav. Brain Res. 90:1998;199-201.
    • (1998) Behav. Brain Res. , vol.90 , pp. 199-201
    • Demas, G.E.1    Nelson, R.J.2    Krueger, B.K.3    Yarowsky, P.J.4
  • 13
    • 0000876182 scopus 로고    scopus 로고
    • A primer for behavioral research
    • Denenberg V.H. A primer for behavioral research. Dev. Disab. Res. Rev. 2:1996;209-215.
    • (1996) Dev. Disab. Res. Rev. , vol.2 , pp. 209-215
    • Denenberg, V.H.1
  • 16
    • 0015965912 scopus 로고
    • Human memory and the cholinergic system
    • Drachman D., Leavitt J. Human memory and the cholinergic system. Arch. Neurol. 30:1974;113-121.
    • (1974) Arch. Neurol. , vol.30 , pp. 113-121
    • Drachman, D.1    Leavitt, J.2
  • 19
    • 0035022091 scopus 로고    scopus 로고
    • On the cause of mental retardation on Down syndrome: Extrapolation from full and segmental trisomy 16 mouse models
    • Galdzicki Z., Siarey R., Pearce R., Stoll J., Rapoport S. On the cause of mental retardation on Down syndrome: extrapolation from full and segmental trisomy 16 mouse models. Brain Res. Rev. 35:2001;115-145.
    • (2001) Brain Res. Rev. , vol.35 , pp. 115-145
    • Galdzicki, Z.1    Siarey, R.2    Pearce, R.3    Stoll, J.4    Rapoport, S.5
  • 20
    • 0034097607 scopus 로고    scopus 로고
    • Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome
    • Granholm A.-Ch, Sanders L.A., Crnic L.S. Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome. Exp. Neurol. 161:2000;647-663.
    • (2000) Exp. Neurol. , vol.161 , pp. 647-663
    • Granholm, A.-Ch.1    Sanders, L.A.2    Crnic, L.S.3
  • 21
    • 0035029836 scopus 로고    scopus 로고
    • Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down's syndrome
    • Head E., Azizeh B.Y., Lott I.T., Tenner A.J., Cotman C.W., Cribbs D.H. Complement association with neurons and beta-amyloid deposition in the brains of aged individuals with Down's syndrome. Neurobiol. Dis. 8:2001;252-265.
    • (2001) Neurobiol. Dis. , vol.8 , pp. 252-265
    • Head, E.1    Azizeh, B.Y.2    Lott, I.T.3    Tenner, A.J.4    Cotman, C.W.5    Cribbs, D.H.6
  • 23
    • 0035208315 scopus 로고    scopus 로고
    • Age-related deficits in context discrimination learning in Ts65Dn mice that model Down's syndrome and Alzheimer's disease
    • Hyde L.A., Crnic L.S. Age-related deficits in context discrimination learning in Ts65Dn mice that model Down's syndrome and Alzheimer's disease. Behav. Neurosci. 115:(6):2001;1239-1246.
    • (2001) Behav. Neurosci. , vol.115 , Issue.6 , pp. 1239-1246
    • Hyde, L.A.1    Crnic, L.S.2
  • 24
    • 0032473584 scopus 로고    scopus 로고
    • Water version of the radial-arm maze: Learning in three inbred strains of mice
    • Hyde L.A., Hoplight B.J., Denenberg V.H. Water version of the radial-arm maze: learning in three inbred strains of mice. Brain Res. 785:(2):1998;236-244.
    • (1998) Brain Res. , vol.785 , Issue.2 , pp. 236-244
    • Hyde, L.A.1    Hoplight, B.J.2    Denenberg, V.H.3
  • 25
    • 0034725155 scopus 로고    scopus 로고
    • Non-spatial water radial-arm maze learning in mice
    • Hyde L., Sherman G., Denenberg V. Non-spatial water radial-arm maze learning in mice. Brain Res. 863:2000;151-159.
    • (2000) Brain Res. , vol.863 , pp. 151-159
    • Hyde, L.1    Sherman, G.2    Denenberg, V.3
  • 26
    • 0021687512 scopus 로고
    • On the role of hippocampal connections in the performance of place and cue tasks: Comparisons with damage to hippocampus
    • Jarrard L., Okaichi H., Steward O., Goldschmidt R. On the role of hippocampal connections in the performance of place and cue tasks: comparisons with damage to hippocampus. Behav. Neurosci. 98:(6):1984;946-954.
    • (1984) Behav. Neurosci. , vol.98 , Issue.6 , pp. 946-954
    • Jarrard, L.1    Okaichi, H.2    Steward, O.3    Goldschmidt, R.4
  • 27
    • 0033970177 scopus 로고    scopus 로고
    • Synaptic deficit in the temporal cortex of partial trisomy 16 [Ts65Dn] mice
    • Kurt M.A., Davies D.C., Kidd M., Dierssen M., Florez J. Synaptic deficit in the temporal cortex of partial trisomy 16 [Ts65Dn] mice. Brain Res. 858:2000;191-197.
    • (2000) Brain Res. , vol.858 , pp. 191-197
    • Kurt, M.A.1    Davies, D.C.2    Kidd, M.3    Dierssen, M.4    Florez, J.5
  • 28
    • 0024503377 scopus 로고
    • The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's Syndrome
    • Mann D.M., Esiri M.M. The pattern of acquisition of plaques and tangles in the brains of patients under 50 years of age with Down's Syndrome. J. Neurol. Sci. 89:1989;169-179.
    • (1989) J. Neurol. Sci. , vol.89 , pp. 169-179
    • Mann, D.M.1    Esiri, M.M.2
  • 29
    • 0030709340 scopus 로고    scopus 로고
    • Cholinergic, serotonergic, and catecholaminergic neurons are not affected in Ts65Dn mice
    • Megias M., Verduga R., Diersson M., Florez J., Insausti R., Crespo D. Cholinergic, serotonergic, and catecholaminergic neurons are not affected in Ts65Dn mice. Neuroreport. 8:1997;3475-3478.
    • (1997) Neuroreport , vol.8 , pp. 3475-3478
    • Megias, M.1    Verduga, R.2    Diersson, M.3    Florez, J.4    Insausti, R.5    Crespo, D.6
  • 30
    • 0032904490 scopus 로고    scopus 로고
    • Distrisbution and retrograde transport of trophic factors in the central nervous system: Functional implications for the treatment of neurodegenerative diseases
    • Mufson E.J., Kroin J.S., Sendera T.J., Sobreviela T. Distrisbution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases. Prog. Neurobiol. 57:(4):1999;451-484.
    • (1999) Prog. Neurobiol. , vol.57 , Issue.4 , pp. 451-484
    • Mufson, E.J.1    Kroin, J.S.2    Sendera, T.J.3    Sobreviela, T.4
  • 31
    • 0000432897 scopus 로고
    • Neural and cognitive development in Down syndrome
    • L. Nadel, & D.M. Rosenthal. New York: Wiley-Liss
    • Nadel L. Neural and cognitive development in Down syndrome. Nadel L., Rosenthal D.M. Down Syndrome: Living and Learning in the Community. 1994;219-241 Wiley-Liss, New York.
    • (1994) Down Syndrome: Living and Learning in the Community , pp. 219-241
    • Nadel, L.1
  • 32
    • 0028969073 scopus 로고
    • Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports
    • Ohkura T., Isse K., Akazawa K., Hamamoto M., Yaoi Y., Hagino N. Long-term estrogen replacement therapy in female patients with dementia of the Alzheimer type: 7 case reports. Dementia. 6:(2):1995;99-107.
    • (1995) Dementia , vol.6 , Issue.2 , pp. 99-107
    • Ohkura, T.1    Isse, K.2    Akazawa, K.3    Hamamoto, M.4    Yaoi, Y.5    Hagino, N.6
  • 34
    • 0033980511 scopus 로고    scopus 로고
    • Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice
    • Richtsmeier J.T., Baxter L.L., Reeves R.H. Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice. Dev. Dyn. 217:2000;137-145.
    • (2000) Dev. Dyn. , vol.217 , pp. 137-145
    • Richtsmeier, J.T.1    Baxter, L.L.2    Reeves, R.H.3
  • 35
    • 0031414807 scopus 로고    scopus 로고
    • Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down syndrome
    • Siarey R.J., Stoll J., Rapoport S.I., Galdzicki Z. Altered long-term potentiation in the young and old Ts65Dn mouse, a model for Down syndrome. Neuropharmacology. 36:1997;1549-1554.
    • (1997) Neuropharmacology , vol.36 , pp. 1549-1554
    • Siarey, R.J.1    Stoll, J.2    Rapoport, S.I.3    Galdzicki, Z.4
  • 36
    • 0032729863 scopus 로고    scopus 로고
    • Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome
    • Siarey R.J., Carlson E.J., Epstein C.J., Balbo A., Rapoport S.I., Galdzicki Z. Increased synaptic depression in the Ts65Dn mouse, a model for mental retardation in Down syndrome. Neropharmocology. 38:1999;1917-1920.
    • (1999) Neropharmocology , vol.38 , pp. 1917-1920
    • Siarey, R.J.1    Carlson, E.J.2    Epstein, C.J.3    Balbo, A.4    Rapoport, S.I.5    Galdzicki, Z.6
  • 37
    • 0034941330 scopus 로고    scopus 로고
    • Nerve growth factor signaling, neuroprotection, and neural repair
    • Sofroniew M., Howe C., Mobley W.C. Nerve growth factor signaling, neuroprotection, and neural repair. Ann. Rev. Neurosci. 24:2001;1217-1281.
    • (2001) Ann. Rev. Neurosci. , vol.24 , pp. 1217-1281
    • Sofroniew, M.1    Howe, C.2    Mobley, W.C.3
  • 38
    • 0027248034 scopus 로고
    • The development of learning difficulties in children with Down's syndrome
    • Wishart J.G. The development of learning difficulties in children with Down's syndrome. J. Intell. Disabil. Res. 37:1993;389-403.
    • (1993) J. Intell. Disabil. Res. , vol.37 , pp. 389-403
    • Wishart, J.G.1
  • 39
    • 0021956826 scopus 로고
    • The cholinergic deficit in Alzheimer's disease
    • Wisnieski K.E., Wisnieski H.M., Wen G.Y. The cholinergic deficit in Alzheimer's disease. Ann. Neurol. 17:1985;278-282.
    • (1985) Ann. Neurol. , vol.17 , pp. 278-282
    • Wisnieski, K.E.1    Wisnieski, H.M.2    Wen, G.Y.3
  • 40
    • 0021049766 scopus 로고
    • Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome
    • Yates C.M., Simpson A., Gordon A.F., Maloney J., Allison Y., Ritchie I.M., Urquart A. Catecholamines and cholinergic enzymes in pre-senile and senile Alzheimer-type dementia and Down's syndrome. Brain Res. 280:1983;119-126.
    • (1983) Brain Res. , vol.280 , pp. 119-126
    • Yates, C.M.1    Simpson, A.2    Gordon, A.F.3    Maloney, J.4    Allison, Y.5    Ritchie, I.M.6    Urquart, A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.