Down's syndrome-like cardiac developmental defects in embryos of the transchromosomic Tc1 mouse

Cardiovascular Research

Volumn 88, Issue 2, 2010, Pages 287-295

  Dunlevy, Louisa ^a   Bennett, Mike ^a   Slender, Amy ^a   Lana Elola, Eva ^a   Tybulewicz, Victor L ^a   Fisher, Elizabeth M C ^b   Mohun, Timothy ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

3D modelling; AVSD; Down syndrome; Mouse model

Indexed keywords

DSCAM PROTEIN; DYRK1A PROTEIN; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME 21; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DIPLOIDY; DOWN SYNDROME; EMBRYO; ENDOCARDIAL CUSHION DEFECT; FEMALE; GENOME; HEART LEFT VENTRICLE OUTFLOW TRACT; HEART RIGHT VENTRICLE OUTFLOW TRACT; HEART SEPTUM DEFECT; HEART VALVE; HEART VENTRICLE SEPTUM DEFECT; HIGH RESOLUTION EPISCOPIC MICROSCOPY; MALE; MICROSCOPY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; SYNTENY; TC1 MOUSE; THREE DIMENSIONAL IMAGING; TRISOMY; VALVULAR HEART DISEASE;

ABNORMALITIES, MULTIPLE; ANIMALS; AORTA; CHROMOSOMES, HUMAN, PAIR 21; DISEASE MODELS, ANIMAL; DOWN SYNDROME; EMBRYO, MAMMALIAN; ENDOCARDIAL CUSHION DEFECTS; FETAL HEART; GENOTYPE; GESTATIONAL AGE; HEART SEPTAL DEFECTS, ATRIAL; HEART SEPTAL DEFECTS, VENTRICULAR; HUMANS; IMAGING, THREE-DIMENSIONAL; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICROSCOPY; MORPHOGENESIS; PHENOTYPE;

EID: 77958094945     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvq193     Document Type: Article

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