Dysfunctional hippocampal inhibition in the Ts65Dn mouse model of Down syndrome

Experimental Neurology

Volumn 233, Issue 2, 2012, Pages 749-757

  Best, Tyler K ^a   Cramer, Nathan P ^a   Chakrabarti, Lina ^b,c   Haydar, Tarik F ^b,c   Galdzicki, Zygmunt ^a,b,c  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Down syndrome; GABA B; GABAergic modulation; GIRK; Hippocampus; Mental retardation; Ts65Dn

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL DISRUPTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN SYNDROME; EVOKED RESPONSE; GABAERGIC TRANSMISSION; HIPPOCAMPAL CA1 REGION; INHIBITORY POSTSYNAPTIC POTENTIAL; MOUSE; NERVE CELL INHIBITION; NERVE CELL NETWORK; NERVE CELL PLASTICITY; NERVE STIMULATION; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STRATUM LACUNOSUM MOLECULARE; STRATUM RADIATUM; SYNAPTIC INHIBITION;

ANIMALS; CA1 REGION, HIPPOCAMPAL; DISEASE MODELS, ANIMAL; DOWN SYNDROME; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; INHIBITORY POSTSYNAPTIC POTENTIALS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURAL INHIBITION; ORGAN CULTURE TECHNIQUES; RECEPTORS, GABA-A; RECEPTORS, GABA-B; SIGNAL TRANSDUCTION;

EID: 84856535551     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.11.033     Document Type: Article

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