The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome

Journal of Neuroscience

Volumn 29, Issue 18, 2009, Pages 5938-5948

  Belichenko, Nadia P ^a   Belichenko, Pavel V ^a   Kleschevnikov, Alexander M ^a   Salehi, Ahmad ^a   Reeves, Roger H ^b   Mobley, William C ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID;

ARTICLE; CHROMOSOME 16; COGNITION; DENDRITIC SPINE; DENTATE GYRUS; DOWN SYNDROME; LONG TERM POTENTIATION; NEUROBIOLOGY; NEUROTRANSMISSION; PHENOTYPE; PRIORITY JOURNAL; SYNAPSE;

ANIMALS; BEHAVIOR, ANIMAL; BODY WEIGHT; BRAIN; DENDRITIC SPINES; DISEASE MODELS, ANIMAL; DOWN SYNDROME; EXPLORATORY BEHAVIOR; HIPPOCAMPUS; LONG-TERM POTENTIATION; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MOTOR ACTIVITY; NEURONS; ORGAN SIZE; PATTERN RECOGNITION, VISUAL; PHENOTYPE; SYNAPSES; TRISOMY;

EID: 65949098892     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1547-09.2009     Document Type: Article

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