Environmental enrichment decreases gabaergic inhibition and improves cognitive abilities, synaptic plasticity and visual functions in a mouse model of down syndrome

Frontiers in Cellular Neuroscience

Volumn , Issue DECEMBER, 2011, Pages 1-22

  Begenisic, Tatjana ^a   Spolidoro, Maria ^a   Braschi, Chiara ^b   Baroncelli, Laura ^c   Milanese, Marco ^d   Pietra, Gianluca ^c   Fabbri, Maria Elena ^c   Bonanno, Giambattista ^d   Cioni, Giovanni ^e   Maffei, Lamberto ^a,c   Sale, Alessandro ^c  

^a SCUOLA NORMALE SUPERIORE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c CNR   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

^e DEPARTMENT OF DEVELOPMENTAL NEUROSCIENCE   (Italy)

Author keywords

Cerebral plasticity; Down syndrome; Environmental enrichment; GABAergic inhibition; Ts65Dn mice

Indexed keywords

4 AMINOBUTYRIC ACID; AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN B; MYXOVIRUS RESISTANCE PROTEIN;

4 AMINOBUTYRIC ACID BRAIN LEVEL; 4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN SYNAPTOSOME; CHROMOSOME MAP; COGNITION; CONTROLLED STUDY; DOWN SYNDROME; ENVIRONMENTAL ENRICHMENT; EVOKED VISUAL RESPONSE; FEMALE; GABAERGIC INHIBITION; GENOTYPE; MALE; MAZE TEST; MOUSE; NERVE CELL PLASTICITY; NERVOUS SYSTEM FUNCTION; NONHUMAN; SENSORIMOTOR FUNCTION; SPATIAL MEMORY; VISION; VISUAL STIMULATION;

EID: 84859104981     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2011.00029     Document Type: Article

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